Primary Site >> Pancreatic Cancer

Gene >> GDNF

Journal: Int J Cancer. 1999 Mar 31;81(1):67-73.
Title: Experimental implication of celiac ganglionotropic invasion of pancreatic-cancer cells bearing c-ret proto-oncogene with reference to glial-cell-line-derived neurotrophic factor (GDNF).
Author: Okada, Y|Takeyama, H|Sato, M|Morikawa, M|Sobue, K|Asai, K|Tada, T|Kato, T|Manabe, T
PMID: 10077155
Journal: Pancreas. 2003 Aug;27(2):190-6.
Title: Alteration of integrin expression by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cells.
Author: Funahashi, Hitoshi|Takeyama, Hiromitsu|Sawai, Hirozumi|Furuta, Akiyoshi|Sato, Mikinori|Okada, Yuji|Hayakawa, Tetsushi|Tanaka, Moritsugu|Manabe, Tadao
PMID: 12883269
Journal: Pancreas. 2004 Jul;29(1):22-7.
Title: Glial cell line-derived neurotrophic factor enhances nuclear factor-kappaB activity and invasive potential in human pancreatic cancer cells.
Author: Takahashi, Hiroki|Funahashi, Hitoshi|Sawai, Hirozumi|Sakamoto, Masaki|Matsuo, Yoichi|Yamamoto, Minoru|Okada, Yuji|Hayakawa, Tetsushi|Manabe, Tadao
PMID: 15211107
Journal: Cancer Res. 2004 Aug 1;64(15):5291-300.
Title: Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells.
Author: Veit, Christine|Genze, Felicitas|Menke, Andre|Hoeffert, Silke|Gress, Thomas M|Gierschik, Peter|Giehl, Klaudia
PMID: 15289335
Journal: J Surg Oncol. 2005 Jul 1;91(1):77-83.
Title: The role of glial cell line-derived neurotrophic factor (GDNF) and integrins for invasion and metastasis in human pancreatic cancer cells.
Author: Funahashi, Hitoshi|Okada, Yuji|Sawai, Hirozumi|Takahashi, Hiroki|Matsuo, Yoichi|Takeyama, Hiromitsu|Manabe, Tadao
PMID: 15999351
Journal: Surgery. 2005 Oct;138(4):788-94.
Title: Expression of glial cell line-derived neurotrophic factor family members and their receptors in pancreatic cancers.
Author: Ito, Yoshinori|Okada, Yuji|Sato, Mikinori|Sawai, Hirozumi|Funahashi, Hitoshi|Murase, Takayuki|Hayakawa, Tetsushi|Manabe, Tadao
PMID: 16269310
Journal: Cancer Res. 2005 Dec 15;65(24):11536-44.
Title: The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.
Author: Sawai, Hirozumi|Okada, Yuji|Kazanjian, Kevork|Kim, Joseph|Hasan, Sascha|Hines, Oscar J|Reber, Howard A|Hoon, Dave S B|Eibl, Guido
PMID: 16357163
Journal: JOP. 2007 Jul 9;8(4 Suppl):501-8.
Title: Antiproteases in preventing the invasive potential of pancreatic cancer cells.
Author: Takahashi, Hiroki|Sawai, Hirozumi|Funahashi, Hitoshi|Matsuo, Yoichi|Yasuda, Akira|Ochi, Nobuo|Sato, Mikinori|Okada, Yuji|Takeyama, Hiromitsu
PMID: 17625307
Journal: J Int Med Res. 2008 Jul-Aug;36(4):656-64.
Title: The relationship between overexpression of glial cell-derived neurotrophic factor and its RET receptor with progression and prognosis of human pancreatic cancer.
Author: Zeng, Q|Cheng, Y|Zhu, Q|Yu, Z|Wu, X|Huang, K|Zhou, M|Han, S|Zhang, Q
PMID: 18652760
Journal: Int J Oncol. 2009 Dec;35(6):1237-45.
Title: Activation of two distinct MAPK pathways governs constitutive expression of matrix metalloproteinase-1 in human pancreatic cancer cell lines.
Author: Endo, Hitoshi|Watanabe, Tetsu|Sugioka, Yoshihiko|Niioka, Maki|Inagaki, Yutaka|Okazaki, Isao
PMID: 19885545
Journal: Mol Cell Biol. 2009 Apr;29(8):2264-77.
Title: Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor alpha1 expression.
Author: Kim, Mi-Hwa|Kim, Hong-Beum|Acharya, Samudra|Sohn, Hong-Moon|Jun, Jae Yeoul|Chang, In-Youb|You, Ho Jin
PMID: 19188437
Journal: World J Surg. 2009 Apr;33(4):710-5.
Title: CXCR2 and RET single nucleotide polymorphisms in pancreatic cancer.
Author: Donahue, Timothy R|Hines, O Joe
PMID: 19057948
Journal: J Natl Cancer Inst. 2010 Jan 20;102(2):107-18.
Title: Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves.
Author: Gil, Ziv|Cavel, Oren|Kelly, Kaitlyn|Brader, Peter|Rein, Avigail|Gao, Sizhi P|Carlson, Diane L|Shah, Jatin P|Fong, Yuman|Wong, Richard J
PMID: 20068194
Journal: Ann Surg Oncol. 2010 Aug;17(8):2213-21.
Title: Positive expression of L1-CAM is associated with perineural invasion and poor outcome in pancreatic ductal adenocarcinoma.
Author: Ben, Qi-Wen|Wang, Jian-Cheng|Liu, Jun|Zhu, Ying|Yuan, Fei|Yao, Wei-Yan|Yuan, Yao-Zong
PMID: 20162456
Journal: Mol Cell Biochem. 2011 Jan;347(1-2):95-101.
Title: High glucose promotes cell proliferation and enhances GDNF and RET expression in pancreatic cancer cells.
Author: Liu, Han|Ma, Qingyong|Li, Junhui
PMID: 20960036
Journal: Biochim Biophys Acta. 2012 Aug;1826(1):112-20.
Title: Role of glial cell line-derived neurotrophic factor in perineural invasion of pancreatic cancer.
Author: Liu, Han|Li, Xuqi|Xu, Qinhong|Lv, Shifang|Li, Junhui|Ma, Qingyong
PMID: 22503821
Journal: Front Physiol. 2012 Apr 17;3:97.
Title: Nerve-cancer interactions in the stromal biology of pancreatic cancer.
Author: Demir, Ihsan Ekin|Friess, Helmut|Ceyhan, Guralp O
PMID: 22529816
Journal: PLoS One. 2012;7(6):e39925.
Title: Radiation impairs perineural invasion by modulating the nerve microenvironment.
Author: Bakst, Richard L|Lee, Nancy|He, Shuangba|Chernichenko, Natalya|Chen, Chun-Hao|Linkov, Gary|Le, H Carl|Koutcher, Jason|Vakiani, Efsevia|Wong, Richard J
PMID: 22768171
Journal: Cancer Res. 2012 Nov 15;72(22):5733-43.
Title: Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor.
Author: Cavel, Oren|Shomron, Olga|Shabtay, Ayelet|Vital, Joseph|Trejo-Leider, Leonor|Weizman, Noam|Krelin, Yakov|Fong, Yuman|Wong, Richard J|Amit, Moran|Gil, Ziv
PMID: 22971345
Journal: Asian J Surg. 2013 Jan;36(1):7-12.
Title: GPC-1 may serve as a predictor of perineural invasion and a prognosticator of survival in pancreatic cancer.
Author: Duan, Lian|Hu, Xian-qiao|Feng, De-yun|Lei, Shi-yue|Hu, Guo-huang
PMID: 23270819
Journal: J Magn Reson Imaging. 2014 Nov;40(5):1071-81.
Title: Ultrashort echo time (UTE) imaging of receptor targeted magnetic iron oxide nanoparticles in mouse tumor models.
Author: Wang, Liya|Zhong, Xiaodong|Qian, Weiping|Huang, Jing|Cao, Zehong|Yu, Qiqi|Lipowska, Malgorzata|Lin, Run|Wang, Andrew|Yang, Lily|Mao, Hui
PMID: 25485347
Journal: Oncogene. 2017 Jun 8;36(23):3232-3239.
Title: Upregulation of RET induces perineurial invasion of pancreatic adenocarcinoma.
Author: Amit, M|Na'ara, S|Leider-Trejo, L|Binenbaum, Y|Kulish, N|Fridman, E|Shabtai-Orbach, A|Wong, R J|Gil, Z
PMID: 28092668