Primary Site >> Colorectal Cancer

Gene >> GAST

Journal: Cancer Res. 1993 Jun 15;53(12):2919-26.
Title: Expression of the gastrin gene in the normal human colon and colorectal adenocarcinoma.
Author: Finley, G G|Koski, R A|Melhem, M F|Pipas, J M|Meisler, A I
PMID: 8504433
Journal: Gastroenterology. 1993 Apr;104(4):1099-107.
Title: Expression but incomplete maturation of progastrin in colorectal carcinomas.
Author: Van Solinge, W W|Nielsen, F C|Friis-Hansen, L|Falkmer, U G|Rehfeld, J F
PMID: 8462798
Journal: Life Sci. 1994;54(10):671-8.
Title: Gastrin gene expression in human colon cancer cells measured by a simple competitive PCR method.
Author: Xu, Z|Dai, B|Dhruva, B|Singh, P
PMID: 7509020
Journal: Gastroenterology. 1996 Jul;111(1):268-9.
Title: Gastrin gene products and gastrin receptors in colon cancer.
Author: Singh, P
PMID: 8698216
Journal: Cancer Res. 1996 Sep 15;56(18):4111-5.
Title: Gastrin gene expression is required for the proliferation and tumorigenicity of human colon cancer cells.
Author: Singh, P|Owlia, A|Varro, A|Dai, B|Rajaraman, S|Wood, T
PMID: 8797575
Journal: Zhonghua Zhong Liu Za Zhi. 1997 May;19(3):192-5.
Title: [Significance of endocrine cells and their hormones in colorectal cancer].
Author: Yin, J|Liang, Y|Wang, H
PMID: 10920894
Journal: Gastroenterology. 1998 Nov;115(5):1144-53.
Title: Oncogenic ras induces gastrin gene expression in colon cancer.
Author: Nakata, H|Wang, S L|Chung, D C|Westwick, J K|Tillotson, L G
PMID: 9797369
Journal: Mol Med. 1999 Mar;5(3):147-59.
Title: Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells.
Author: Stepan, V M|Sawada, M|Todisco, A|Dickinson, C J
PMID: 10404512
Journal: Gastroenterology. 2000 Jul;119(1):162-71.
Title: Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen.
Author: Singh, P|Velasco, M|Given, R|Varro, A|Wang, T C
PMID: 10889165
Journal: J Biol Chem. 2000 Oct 20;275(42):32491-8.
Title: Autocrine gastrins in colon cancer cells Up-regulate cytochrome c oxidase Vb and down-regulate efflux of cytochrome c and activation of caspase-3.
Author: Wu, H|Rao, G N|Dai, B|Singh, P
PMID: 10915781
Journal: J Clin Invest. 2000 Aug;106(4):533-9.
Title: Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis.
Author: Koh, T J|Bulitta, C J|Fleming, J V|Dockray, G J|Varro, A|Wang, T C
PMID: 10953028
Journal: Int J Colorectal Dis. 2001 Aug;16(4):202-10.
Title: Helicobacter pylori infection, gastrin, cyclooxygenase-2, and apoptosis in colorectal cancer.
Author: Hartwich, A|Konturek, S J|Pierzchalski, P|Zuchowicz, M|Labza, H|Konturek, P C|Karczewska, E|Bielanski, W|Marlicz, K|Starzynska, T|Lawniczak, M|Hahn, E G
PMID: 11515678
Journal: Med Sci Monit. 2001 Nov-Dec;7(6):1171-81.
Title: Molecular basis of colorectal cancer - role of gastrin and cyclooxygenase-2.
Author: Hartwich, J|Konturek, S J|Pierzchalski, P|Zuchowicz, M|Konturek, P C|Bielanski, W|Marlicz, K|Starzynska, T|Lawniczak, M
PMID: 11687726
Journal: Dig Dis Sci. 2002 Sep;47(9):1984-91.
Title: Progastrin and cyclooxygenase-2 in colorectal cancer.
Author: Konturek, Peter C|Bielanski, Wladyslaw|Konturek, Stanislaw J|Hartwich, Artur|Pierzchalski, Piotr|Gonciarz, Macien|Marlicz, Krzysztof|Starzynska, Teresa|Zuchowicz, Monika|Darasz, Zbigniew|Gotze, Jens P|Rehfeld, Jens F|Hahn, Eckhart G
PMID: 12353842
Journal: Eur J Clin Invest. 2004 Feb;34(2):100-6.
Title: K-ras and B-raf gene mutations are not associated with gastrin- and CCK2-receptor mRNA expression in human colorectal tumour tissues.
Author: Monstein, H-J|Fransen, K|Dimberg, J|Soderkvist, P
PMID: 14764072
Journal: Surgeon. 2004 Oct;2(5):251-7.
Title: The role of gastrin in colorectal carcinogenesis.
Author: Takhar, A S|Eremin, O|Watson, S A
PMID: 15570843
Journal: Int J Oncol. 2004 Oct;25(4):1049-56.
Title: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR.
Author: Solmi, Rossella|De Sanctis, Paola|Zucchini, Cinzia|Ugolini, Giampaolo|Rosati, Giancarlo|Del Governatore, Marco|Coppola, Domenico|Yeatman, Thymothy J|Lenzi, Luca|Caira, Antonello|Zanotti, Simone|Taffurelli, Mario|Carinci, Paolo|Valvassori, Luisa|Strippoli,
PMID: 15375555
Journal: World J Gastroenterol. 2005 Dec 7;11(45):7211-7.
Title: Correlation between the expressions of gastrin, somatostatin and cyclin and cyclin-depend kinase in colorectal cancer.
Author: Wu, Pei|Mao, Jia-Ding|Yan, Jing-Yi|Rui, Jing|Zhao, You-Cai|Li, Xian-Hai|Xu, Guo-Qiang
PMID: 16437675
Journal: Am J Physiol Gastrointest Liver Physiol. 2006 Mar;290(3):G519-27. Epub 2005 Oct
Title: Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice.
Author: Kanda, Naoki|Seno, Hiroshi|Kawada, Mayumi|Sawabu, Tateo|Uenoyoma, Yoshito|Nakajima, Toshio|Konda, Yoshitaka|Fukui, Hirokazu|Takeuchi, Toshiyuki|Chiba, Tsutomu
PMID: 16254046
Journal: Regul Pept. 2007 Dec 4;144(1-3):25-33.
Title: An upstream CRE-E-box element is essential for gastrin-dependent activation of the cyclooxygenase-2 gene in human colon cancer cells.
Author: Ansorge, Nikolaus|Juttner, Stefan|Cramer, Thorsten|Schmidt, Wolfgang E|Hocker, Michael|Schmitz, Frank
PMID: 17604853
Journal: Gastroenterology. 2007 Nov;133(5):1554-68. Epub 2007 Oct 24.
Title: Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.
Author: Pannequin, Julie|Delaunay, Nathalie|Buchert, Michael|Surrel, Fanny|Bourgaux, Jean-Francois|Ryan, Joanne|Boireau, Stephanie|Coelho, Jessica|Pelegrin, Andre|Singh, Pomila|Shulkes, Arthur|Yim, Mildred|Baldwin, Graham S|Pignodel, Christine|Lambeau, Gerard|Jay
PMID: 17920061
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Nov;11(6):554-7.
Title: [Relationships of the mRNA and protein expression of gastrin with Fas/FasL and caspases in colorectal carcinoma].
Author: Mao, Jia-ding|Wu, Pei|Yang, Ying-lin|Wu, Jian|Hu, Ji-qun|Huang, He
PMID: 19031134
Journal: Chirurg. 2009 Apr;80(4):281-93.
Title: [Individualizing treatment for locally advanced rectal cancer].
Author: Liersch, T|Rothe, H|Ghadimi, B M|Becker, H
PMID: 19350305
Journal: Int J Cancer. 2010 Jun 15;126(12):2847-57.
Title: A gastrin precursor, gastrin-gly, upregulates VEGF expression in colonic epithelial cells through an HIF-1-independent mechanism.
Author: Bertrand, Claudine|Kowalski-Chauvel, Aline|Do, Catherine|Resa, Cecile|Najib, Souad|Daulhac, Laurence|Wang, Timothy C|Ferrand, Audrey|Seva, Catherine
PMID: 19876923
Journal: Gastroenterology. 2013 Jan;144(1):155-66.
Title: Mice that express human interleukin-8 have increased mobilization of immature myeloid cells, which exacerbates inflammation and accelerates colon carcinogenesis.
Author: Asfaha, Samuel|Dubeykovskiy, Alexander N|Tomita, Hiroyuki|Yang, Xiangdong|Stokes, Sarah|Shibata, Wataru|Friedman, Richard A|Ariyama, Hiroshi|Dubeykovskaya, Zinaida A|Muthupalani, Sureshkumar|Ericksen, Russell|Frucht, Harold|Fox, James G|Wang, Timothy C
PMID: 23041326
Journal: Surg Today. 2014 Apr;44(4):677-84.
Title: Catheter-associated bloodstream infection after bowel surgery in patients with inflammatory bowel disease.
Author: Uchino, Motoi|Ikeuchi, Hiroki|Matsuoka, Hiroki|Bando, Toshihiro|Ichiki, Kaoru|Nakajima, Kazuhiko|Takahashi, Yoshiko|Tomita, Naohiro|Takesue, Yoshio
PMID: 23959087
Journal: Biochim Biophys Acta. 2014 Nov;1843(11):2471-80.
Title: Gastrin mediates resistance to hypoxia-induced cell death in xenografts of the human colorectal cancer cell line LoVo.
Author: Westwood, David A|Patel, Oneel|Baldwin, Graham S
PMID: 24998603
Journal: Metallomics. 2015 Oct;7(10):1390-8.
Title: Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo.
Author: Marshall, Kathryn M|Laval, Marie|Estacio, Ortis|Hudson, Damien F|Kalitsis, Paul|Shulkes, Arthur|Baldwin, Graham S|Patel, Oneel
PMID: 26404630