Primary Site >> Liver Cancer

Gene >> GADD45A

Journal: Mol Biol Rep. 2003 Dec;30(4):249-53.
Title: GADD45gamma, down-regulated in 65% hepatocellular carcinoma (HCC) from 23 chinese patients, inhibits cell growth and induces cell cycle G2/M arrest for hepatoma Hep-G2 cell lines.
Author: Sun, Luhong|Gong, Ruomu|Wan, Bo|Huang, Xinghua|Wu, Chaoqun|Zhang, Xirang|Zhao, Shouyuan|Yu, Long
PMID: 14672412
Journal: Int J Environ Res Public Health. 2005 Aug;2(2):355-61.
Title: Cytotoxicity and expression of c-fos, HSP70, and GADD45/153 proteins in human liver carcinoma (HepG2) cells exposed to dinitrotoluenes.
Author: Glass, Konsuela Y|Newsome, Cecilia R|Tchounwou, Paul B
PMID: 16705839
Journal: J Cell Biochem. 2008 Aug 15;104(6):2174-84.
Title: Gliotoxin enhances radiotherapy via inhibition of radiation-induced GADD45a, p38, and NFkappaB activation.
Author: Hur, Jung-Mu|Yun, Hye-Jeong|Yang, Soo-Hyung|Lee, Woo-Yiel|Joe, Min-Ho|Kim, Dongho
PMID: 18425744
Journal: BMC Genomics. 2008 Oct 16;9:487.
Title: Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT.
Author: Kiyosawa, Naoki|Kwekel, Joshua C|Burgoon, Lyle D|Dere, Edward|Williams, Kurt J|Tashiro, Colleen|Chittim, Brock|Zacharewski, Timothy R
PMID: 18925944
Journal: Int J Cancer. 2009 Feb 15;124(4):816-26.
Title: Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility.
Author: Liao, Yi-Jen|Liu, Shih-Ping|Lee, Cheng-Ming|Yen, Chia-Hung|Chuang, Pei-Chun|Chen, Chia-Yen|Tsai, Ting-Fen|Huang, Shiu-Feng|Lee, Yan-Hwa Wu|Chen, Yi-Ming Arthur
PMID: 19035462
Journal: Mol Biol Rep. 2009 Nov;36(8):2075-85.
Title: Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells.
Author: Zhu, Na|Shao, Yan|Xu, Lin|Yu, Long|Sun, Luhong
PMID: 19048389
Journal: Toxicol In Vitro. 2013 Sep;27(6):1809-19.
Title: Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells.
Author: Straser, Alja|Filipic, Metka|Zegura, Bojana
PMID: 23726867
Journal: Adv Exp Med Biol. 2013;793:69-80.
Title: Gadd45 in the liver: signal transduction and transcriptional mechanisms.
Author: Tian, Jianmin|Locker, Joseph
PMID: 24104474
Journal: Cancer Res. 2014 Mar 1;74(5):1452-62.
Title: Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes.
Author: Ma, Leina|Liu, Jia|Liu, Limei|Duan, Guangjie|Wang, Qingliang|Xu, Yanmin|Xia, Feng|Shan, Juanjuan|Shen, Junjie|Yang, Zhi|Bie, Ping|Cui, Youhong|Bian, Xiu-Wu|Prieto, Jesus|Avila, Matias A|Qian, Cheng
PMID: 24390737
Journal: Dig Dis Sci. 2014 Aug;59(8):1798-809.
Title: Downregulating sCLU enhances the sensitivity of hepatocellular carcinoma cells to gemcitabine by activating the intrinsic apoptosis pathway.
Author: Xiu, Peng|Xu, Zongzhen|Liu, Feng|Li, Ziqiang|Li, Tao|Zou, Fang|Sun, Xueying|Li, Jie
PMID: 24671452
Journal: Oncotarget. 2015 Sep 29;6(29):27953-65.
Title: Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma.
Author: Ou, Da-Liang|Shyue, Song-Kun|Lin, Liang-In|Feng, Zi-Rui|Liou, Jun-Yang|Fan, Hsiang-Hsuan|Lee, Bin-Shyun|Hsu, Chiun|Cheng, Ann-Lii
PMID: 26172295
Journal: Environ Sci Pollut Res Int. 2016 Aug;23(15):14751-61.
Title: Influence of selected anti-cancer drugs on the induction of DNA double-strand breaks and changes in gene expression in human hepatoma HepG2 cells.
Author: Novak, Matjaz|Zegura, Bojana|Baebler, Spela|Stern, Alja|Rotter, Ana|Stare, Katja|Filipic, Metka
PMID: 26392091
Journal: Tumour Biol. 2016 May;37(5):5951-61.
Title: Derivate isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis.
Author: Chen, Lijuan|Tian, Hua|Li, Meng|Ge, Chao|Zhao, Fangyu|Zhang, Lixing|Li, Hong|Liu, Junxi|Wang, Tingpu|Yao, Ming|Li, Jinjun
PMID: 26596832
Journal: J Cancer. 2018 Apr 6;9(8):1403-1413.
Title: Secretory Clusterin Mediates Oxaliplatin Resistance via the Gadd45a/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma.
Author: Wang, Xin|Zou, Fang|Zhong, Jingtao|Yue, Longtao|Wang, Fuhai|Wei, Honglong|Yang, Guangsheng|Jin, Tao|Dong, Xiaofeng|Li, Jie|Xiu, Peng
PMID: 29721050
Journal: PeerJ. 2018 Jul 18;6:e5203.
Title: Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity.
Author: Kabir, Mohammad Faujul|Mohd Ali, Johari|Haji Hashim, Onn
PMID: 30042885