Primary Site >> Colorectal Cancer

Gene >> GAB1

Journal: Cancer Res. 2004 Apr 1;64(7):2601-9.
Title: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.
Author: Jackson, James G|St Clair, Patricia|Sliwkowski, Mark X|Brattain, Michael G
PMID: 15059917
Journal: J Biol Chem. 2004 Oct 8;279(41):43261-72. Epub 2004 Aug 4.
Title: Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Author: Moran, Amy E|Hunt, Daniel H|Javid, Sara H|Redston, Mark|Carothers, Adelaide M|Bertagnolli, Monica M
PMID: 15294912
Journal: Carcinogenesis. 2008 Mar;29(3):647-55.
Title: Gab1 but not Grb2 mediates tumor progression in Met overexpressing colorectal cancer cells.
Author: Seiden-Long, Isolde|Navab, Roya|Shih, Warren|Li, Ming|Chow, Jane|Zhu, Chang Qi|Radulovich, Nikolina|Saucier, Caroline|Tsao, Ming-Sound
PMID: 18192688
Journal: Oncogene. 2014 Apr 17;33(16):2123-33.
Title: Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.
Author: Cardoso, A P|Pinto, M L|Pinto, A T|Oliveira, M I|Pinto, M T|Goncalves, R|Relvas, J B|Figueiredo, C|Seruca, R|Mantovani, A|Mareel, M|Barbosa, M A|Oliveira, M J
PMID: 23644655
Journal: Int J Cancer. 2015 Nov 15;137(10):2310-22.
Title: MicroRNA-409-3p suppresses colorectal cancer invasion and metastasis partly by targeting GAB1 expression.
Author: Bai, Rongpan|Weng, Chunhua|Dong, Haojie|Li, Siqi|Chen, Guangdi|Xu, Zhengping
PMID: 25991585
Journal: Biochim Biophys Acta. 2016 Oct;1862(10):1926-37.
Title: Novel miR-5582-5p functions as a tumor suppressor by inducing apoptosis and cell cycle arrest in cancer cells through direct targeting of GAB1, SHC1, and CDK2.
Author: An, Hyun-Ju|Kwak, Seo-Young|Yoo, Je-Ok|Kim, Jae-Sung|Bae, In-Hwa|Park, Myung-Jin|Cho, Mee-Yon|Kim, Joon|Han, Young-Hoon
PMID: 27475256