Primary Site >> Liver Cancer

Gene >> FLT1

Journal: Oncol Rep. 2000 Jul-Aug;7(4):725-9.
Title: Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues.
Author: Yamaguchi, R|Yano, H|Nakashima, Y|Ogasawara, S|Higaki, K|Akiba, J|Hicklin, D J|Kojiro, M
PMID: 10854533
Journal: Am J Clin Pathol. 2001 Dec;116(6):838-45.
Title: Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma.
Author: Ng, I O|Poon, R T|Lee, J M|Fan, S T|Ng, M|Tso, W K
PMID: 11764072
Journal: Anticancer Res. 2002 Jan-Feb;22(1A):379-86.
Title: Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: a comparison with angiopoietin/Tie pathway.
Author: Dhar, Dipok Kumar|Naora, Hiroyuki|Yamanoi, Akira|Ono, Takashi|Kohno, Hitoshi|Otani, Hiroki|Nagasue, Naofumi
PMID: 12017318
Journal: Hepatology. 2004 Jun;39(6):1517-24.
Title: Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice.
Author: Yoshiji, Hitoshi|Kuriyama, Shigeki|Yoshii, Junichi|Ikenaka, Yasuhide|Noguchi, Ryuichi|Hicklin, Daniel J|Wu, Yan|Yanase, Koji|Namisaki, Tadashi|Kitade, Mitsuteru|Yamazaki, Masaharu|Tsujinoue, Hirohisa|Masaki, Tsutomu|Fukui, Hiroshi
PMID: 15185292
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-quantum dot-vascular endothelial growth factor
Author: Zhang, Huiming
PMID: 20641777
Journal:
Title: Anti-vascular endothelial growth factor polylactic acid-polyethylene glycol-poly-L-Lys/gadolinium-diethylenetriamine pentaacetic acid nanoparticles
Author: Leung, Kam
PMID: 22812022
Journal: Anticancer Drugs. 2005 Jun;16(5):515-24.
Title: 11,11'-dideoxy-verticillin: a natural compound possessing growth factor receptor tyrosine kinase-inhibitory effect with anti-tumor activity.
Author: Zhang, Yi-Xiang|Chen, Yi|Guo, Xiao-Ning|Zhang, Xiong-Wen|Zhao, Wei-Min|Zhong, Li|Zhou, Jin|Xi, Yong|Lin, Li-Ping|Ding, Jian
PMID: 15846117
Journal: Oncol Rep. 2006 Jul;16(1):3-10.
Title: Expression of vascular endothelial growth factor receptors is closely related to the histological grade of hepatocellular carcinoma.
Author: Amaoka, Nozomi|Saio, Masanao|Nonaka, Kenichi|Imai, Hisashi|Tomita, Hiroyuki|Sakashita, Fumio|Takahashi, Takao|Sugiyama, Yasuyuki|Takami, Tsuyoshi|Adachi, Yosuke
PMID: 16786116
Journal: Pathol Int. 2006 Dec;56(12):717-23.
Title: Organ-specific endoglin (CD105) expression in the angiogenesis of human cancers.
Author: Minhajat, Rahmawati|Mori, Daisuke|Yamasaki, Fumio|Sugita, Yasuo|Satoh, Toshimi|Tokunaga, Osamu
PMID: 17096728
Journal: Gan To Kagaku Ryoho. 2006 Nov;33(12):1841-4.
Title: [The relationship between plasma level of VEGF or soluble Flt-1 and efficacy of hepatic arterial chemotherapy in patients with liver metastasis of colorectal cancer].
Author: Gonda, Tsuyoshi|Okada, Norimichi|Nakada, Hiroshi|Yokoyama, Masaru|Miyazaki, Tatsuya|Ishibashi, Keiichiro|Ishida, Hideyuki|Matsumoto, Yoshiro|Miura, Tsuyoshi
PMID: 17212123
Journal: Acad Radiol. 2007 Sep;14(9):1084-91.
Title: Multiphase contrast-enhanced CT imaging in hepatocellular carcinoma correlation with immunohistochemical angiogenic activities.
Author: Kim, Young Il|Chung, Jin Wook|Park, Jae Hyung|Kang, Gyeong Hoon|Lee, Minjin|Suh, Kyung-Suk|Kim, Kwang Gi
PMID: 17707316
Journal: J Nucl Med. 2008 Jan;49(1):135-41.
Title: Usefulness of 11C-methionine for differentiating tumors from granulomas in experimental rat models: a comparison with 18F-FDG and 18F-FLT.
Author: Zhao, Songji|Kuge, Yuji|Kohanawa, Masashi|Takahashi, Toshiyuki|Zhao, Yan|Yi, Min|Kanegae, Kakuko|Seki, Koh-Ichi|Tamaki, Nagara
PMID: 18077525
Journal: Liver Int. 2008 Apr;28(4):509-18.
Title: Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis.
Author: Kornek, Miroslaw|Raskopf, Esther|Tolba, Rene|Becker, Ursula|Klockner, Maren|Sauerbruch, Tilman|Schmitz, Volker
PMID: 18339078
Journal: Clin Cancer Res. 2009 Dec 15;15(24):7529-7537.
Title: Vascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant {beta}-Catenin Activation in Colon Cancer.
Author: Naik, Snehal|Dothager, Robin S|Marasa, Jayne|Lewis, Cory L|Piwnica-Worms, David
PMID: 20008853
Journal: Epigenetics. 2009 Jul 1;4(5):313-321.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Whang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 28001118
Journal: J Nucl Med. 2009 Sep;50(9):1441-7.
Title: Imaging of proliferation in hepatocellular carcinoma with the in vivo marker 18F-fluorothymidine.
Author: Eckel, Florian|Herrmann, Ken|Schmidt, Stefan|Hillerer, Claudia|Wieder, Hinrich A|Krause, Bernd-Joachim|Schuster, Tibor|Langer, Rupert|Wester, Hans-Jurgen|Schmid, Roland M|Schwaiger, Markus|Buck, Andreas K
PMID: 19690030
Journal: Epigenetics. 2009 Jul 1;4(5):313-21. Epub 2009 Jul 3.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Hwang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 19633424
Journal: Hepatology. 2010 Jan;51(1):255-66.
Title: Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression.
Author: Quiles-Perez, Rosa|Munoz-Gamez, Jose Antonio|Ruiz-Extremera, Angeles|O'Valle, Francisco|Sanjuan-Nunez, Laura|Martin-Alvarez, Ana Belen|Martin-Oliva, David|Caballero, Trinidad|Munoz de Rueda, Paloma|Leon, Josefa|Gonzalez, Raul|Muntane, Jordi|Oliver, Franci
PMID: 20034026
Journal: Cell Signal. 2012 Mar;24(3):779-93.
Title: Modulation of chemotactic and pro-inflammatory activities of endothelial progenitor cells by hepatocellular carcinoma.
Author: Shih, Yu-Tsung|Wang, Mei-Cun|Peng, Hsin-Hsin|Chen, Ting-Fang|Chen, Linyi|Chang, Jang-Yang|Chiu, Jeng-Jiann
PMID: 22120522
Journal: Mol Ther. 2012 May;20(5):938-47.
Title: Soluble vascular endothelial growth factor decoy receptor FP3 exerts potent antiangiogenic effects.
Author: Yu, De-Chao|Lee, Jung-Sun|Yoo, Ji Young|Shin, Hyewon|Deng, Hongxin|Wei, Yuquan|Yun, Chae-Ok
PMID: 22273580
Journal: Mol Imaging Biol. 2013 Jun;15(3):326-35.
Title: Monitoring tumor response with radiolabeled nucleoside analogs in a hepatoma-bearing mouse model early after doxisome((R)) treatment.
Author: Wu, Chun-Yi|Chou, Lin-Shan|Chan, Pei-Chia|Ho, Chung-Hsien|Lin, Ming-Hsien|Shen, Chih-Chieh|Liu, Ren-Shyan|Lin, Wuu-Jyh|Wang, Hsin-Ell
PMID: 23247923
Journal: Mol Cell Proteomics. 2013 May;12(5):1335-49.
Title: Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma.
Author: Liu, Chia-Hung|Chen, Tzu-Chi|Chau, Gar-Yang|Jan, Yi-Hua|Chen, Chun-Houh|Hsu, Chun-Nan|Lin, Kuan-Ting|Juang, Yue-Li|Lu, Pei-Jung|Cheng, Hui-Chuan|Chen, Ming-Huang|Chang, Chia-Fen|Ting, Yu-Shan|Kao, Cheng-Yan|Hsiao, Michael|Huang, Chi-Ying F
PMID: 23397142
Journal: Cancer Chemother Pharmacol. 2013 Dec;72(6):1183-93.
Title: Differential regulation of sunitinib targets predicts its tumor-type-specific effect on endothelial and/or tumor cell apoptosis.
Author: Bousquet, Guilhem|Varna, Mariana|Ferreira, Irmine|Wang, Li|Mongiat-Artus, Pierre|Leboeuf, Christophe|de Bazelaire, Cedric|Faivre, Sandrine|Bertheau, Philippe|Raymond, Eric|Germain, Stephane|Janin, Anne
PMID: 24061866
Journal: Conf Proc IEEE Eng Med Biol Soc. 2013;2013:2700-3.
Title: Differential network biology reveals a positive correlation between a novel protein-protein interaction and cancer cells migration.
Author: Liu, Chia-Hung|Chen, Tzu-Chi|Chen, Chun-Houh|Kao, Cheng-Yan|Huang, Chi-Ying F
PMID: 24110284
Journal: Hepatology. 2014 Oct;60(4):1264-77.
Title: Autocrine vascular endothelial growth factor signaling promotes cell proliferation and modulates sorafenib treatment efficacy in hepatocellular carcinoma.
Author: Peng, Sui|Wang, Ye|Peng, Hong|Chen, Dong|Shen, Shunli|Peng, Baogang|Chen, Minhu|Lencioni, Riccardo|Kuang, Ming
PMID: 24849467
Journal: Vasc Cell. 2014 Sep 6;6:18.
Title: Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage.
Author: Yamamoto, Yuji|Matsui, Junji|Matsushima, Tomohiro|Obaishi, Hiroshi|Miyazaki, Kazuki|Nakamura, Katsuji|Tohyama, Osamu|Semba, Taro|Yamaguchi, Atsumi|Hoshi, Sachi Suzuki|Mimura, Fusayo|Haneda, Toru|Fukuda, Yoshio|Kamata, Jun-Ichi|Takahashi, Keiko|Matsukura,
PMID: 25197551
Journal: EJNMMI Res. 2016 Dec;6(1):63.
Title: The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models.
Author: Heinzmann, Kathrin|Honess, Davina Jean|Lewis, David Yestin|Smith, Donna-Michelle|Cawthorne, Christopher|Keen, Heather|Heskamp, Sandra|Schelhaas, Sonja|Witney, Timothy Howard|Soloviev, Dmitry|Williams, Kaye Janine|Jacobs, Andreas Hans|Aboagye, Eric Ofori|G
PMID: 27515446
Journal: Mol Imaging Biol. 2017 Aug;19(4):540-549.
Title: Response Monitoring with [(18)F]FLT PET and Diffusion-Weighted MRI After Cytotoxic 5-FU Treatment in an Experimental Rat Model for Colorectal Liver Metastases.
Author: Heskamp, Sandra|Heijmen, Linda|Gerrits, Danny|Molkenboer-Kuenen, Janneke D M|Ter Voert, Edwin G W|Heinzmann, Kathrin|Honess, Davina J|Smith, Donna-Michelle|Griffiths, John R|Doblas, Sabrina|Sinkus, Ralph|Laverman, Peter|Oyen, Wim J G|Heerschap, Arend|Boer
PMID: 27798786
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: Mol Med Rep. 2017 Nov;16(5):5799-5806.
Title: Antiangiogenesis gene therapy for hepatocellular carcinoma via systemic injection of mesenchymal stem cells engineered to secrete soluble Flt1.
Author: Li, Guanglin|Miao, Fei|Zhu, Jinhai|Chen, Yanling
PMID: 28849176
Journal: Hepatobiliary Pancreat Dis Int. 2018 Apr;17(2):140-148.
Title: Prediction of tumor biological characteristics in different colorectal cancer liver metastasis animal models using (18)F-FDG and (18)F-FLT.
Author: Xu, Hai-Long|Li, Man|Zhang, Rong-Jun|Jiang, Hui-Jie|Zhang, Ming-Yu|Li, Xin|Wang, Yi-Qiao|Pan, Wen-Bin
PMID: 29571649