Primary Site >> Stomach Cancer

Gene >> FLT1

Journal: Clin Cancer Res. 1996 Oct;2(10):1679-84.
Title: Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer.
Author: Takahashi, Y|Cleary, K R|Mai, M|Kitadai, Y|Bucana, C D|Ellis, L M
PMID: 9816116
Journal: Cancer Res Treat. 2001 Aug;33(4):309-17.
Title: Genetic Alterations in Gastric Carcinomas and Adjacent Mucosa Detected by Comparative Genomic Hybridization (CGH).
Author: Kim, D W|Choi, S J|Lee, J Y|Kim, K J|Park, M I|Park, S J|Koo, S H|Koo, J Y
PMID: 26680801
Journal: World J Gastroenterol. 2002 Dec;8(6):994-8.
Title: Expression of vascular endothelial growth factor and its receptors KDR and Flt-1 in gastric cancer cells.
Author: Zhang, Hua|Wu, Jian|Meng, Lin|Shou, Cheng-Chao
PMID: 12439912
Journal: Zhonghua Yi Xue Za Zhi. 2003 May 10;83(9):782-6.
Title: [Expression of MMP-9 and MMP-9 mRNA in gastric carcinoma and its correlation with angiogenesis].
Author: Wang, Lu|Zhang, Li-hong|Li, Yu-lin|Li, Yi-lei|Liu, Zhan
PMID: 12899759
Journal: Cancer Res. 2004 May 15;64(10):3624-8.
Title: Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer.
Author: Sako, Akihiro|Kitayama, Joji|Koyama, Hiroyuki|Ueno, Hikaru|Uchida, Hiroaki|Hamada, Hirofumi|Nagawa, Hirokazu
PMID: 15150121
Journal: Int J Cancer. 2004 Aug 20;111(2):165-73.
Title: Suppression of tumor growth and metastasis by a VEGFR-1 antagonizing peptide identified from a phage display library.
Author: An, Ping|Lei, Hetian|Zhang, Jianzhi|Song, Shumei|He, Luowen|Jin, Genglin|Liu, Xiaoying|Wu, Jian|Meng, Lin|Liu, Meisheng|Shou, Chengchao
PMID: 15197767
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-quantum dot-vascular endothelial growth factor
Author: Zhang, Huiming
PMID: 20641777
Journal: World J Gastroenterol. 2005 Feb 21;11(7):938-42.
Title: Effect of Weikangning on gastric cancer cell growth and expression of vascular endothelial growth factor and its receptors KDR and Flt-1.
Author: Li, Qing-Ming|Kan, Fang-Ju|Min, Cun-Yun
PMID: 15742392
Journal: Mol Cancer Res. 2005 Nov;3(11):607-15.
Title: Nicotine induces cyclooxygenase-2 and vascular endothelial growth factor receptor-2 in association with tumor-associated invasion and angiogenesis in gastric cancer.
Author: Shin, Vivian Y|Wu, William K K|Chu, Kent-Man|Wong, Helen P S|Lam, Emily K Y|Tai, Emily K K|Koo, Marcel W L|Cho, Chi-Hin
PMID: 16317086
Journal: Oncology. 2006;70(1):63-70.
Title: A phase II study of infusional 5-fluorouracil and low-dose leucovorin with docetaxel for advanced gastric cancer.
Author: Jeung, H-C|Rha, Sun Young|Kim, Yong Tae|Noh, Sung Hoon|Roh, Jae Kyung|Chung, Hyun Cheol
PMID: 16446551
Journal: World J Gastroenterol. 2006 Sep 14;12(34):5465-72.
Title: H pylori status and angiogenesis factors in human gastric carcinoma.
Author: Mangia, Anita|Chiriatti, Annalisa|Ranieri, Girolamo|Abbate, Ines|Coviello, Maria|Simone, Giovanni|Zito, Francesco Alfredo|Montemurro, Severino|Rucci, Antonello|Di Leo, Alfredo|Tommasi, Stefania|Berloco, Pasquale|Xu, Jian Ming|Paradiso, Angelo
PMID: 17006982
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Jun;26 Suppl:88-92.
Title: [Effects of weikangning contained serum on growth of gastric cancer cell, expression of vascular endothelial growth factor and its receptors including KDR and fit-1].
Author: Li, Qing-ming|Kan, Fang-ju|Min, Cun-yun
PMID: 17569358
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2007 May;10(3):269-73.
Title: [Relationship between the expression of vascular endothelial growth factor, fms-like tyrosine kinase-1 and biological behavior in gastric carcinoma].
Author: Wang, Yuan-yu|Ye, Zai-yuan|Zhao, Zhong-sheng|Tao, Hou-quan
PMID: 17633783
Journal: World J Gastroenterol. 2007 Dec 28;13(48):6498-505.
Title: Effect of arsenic trioxide on vascular endothelial cell proliferation and expression of vascular endothelial growth factor receptors Flt-1 and KDR in gastric cancer in nude mice.
Author: Xiao, Yan-Feng|Wu, De-Dong|Liu, Shan-Xi|Chen, Xi|Ren, Li-Fen
PMID: 18161919
Journal: Cancer Chemother Pharmacol. 2008 Feb;61(2):315-21.
Title: A phase II study of paclitaxel combined with infusional 5-fluorouracil and low-dose leucovorin for advanced gastric cancer.
Author: Im, Chong Kun|Jeung, Hei-Cheul|Rha, Sun Young|Yoo, Nae Choon|Noh, Sung Hoon|Roh, Jae Kyung|Chung, Hyun Cheol
PMID: 18026677
Journal: World J Gastroenterol. 2008 Jun 28;14(24):3879-83.
Title: Measurement of circulating levels of VEGF-A, -C, and -D and their receptors, VEGFR-1 and -2 in gastric adenocarcinoma.
Author: Al-Moundhri, Mansour-S|Al-Shukaili, A|Al-Nabhani, M|Al-Bahrani, B|Burney, I-A|Rizivi, A|Ganguly, S-S
PMID: 18609713
Journal: Cancer Sci. 2009 Feb;100(2):310-5.
Title: Impact of vascular endothelial growth factor receptor 1, 2, and 3 expression on the outcome of patients with gastric cancer.
Author: Hirashima, Yoshinori|Yamada, Yasuhide|Matsubara, Junichi|Takahari, Daisuke|Okita, Natsuko|Takashima, Atsuo|Kato, Ken|Hamaguchi, Tetsuya|Shirao, Kuniaki|Shimada, Yasuhiro|Taniguchi, Hirokazu|Shimoda, Tadakazu
PMID: 19068081
Journal: Epigenetics. 2009 Jul 1;4(5):313-21. Epub 2009 Jul 3.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Hwang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 19633424
Journal: Epigenetics. 2009 Jul 1;4(5):313-321.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Whang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 28001118
Journal: Life Sci. 2010 Jun 19;86(25-26):936-41.
Title: Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG.
Author: Manikandan, Palrasu|Murugan, Ramalingam Senthil|Priyadarsini, Ramamurthi Vidya|Vinothini, Govindarajah|Nagini, Siddavaram
PMID: 20434464
Journal: Gan To Kagaku Ryoho. 2010 Aug;37(8):1489-96.
Title: [Impact of HER2, EGFR, IGF-1R, and VEGFR expressions on the outcome of chemotherapy for advanced gastric cancer].
Author: Matsubara, Junichi|Hirashima, Yoshinori|Yamada, Yasuhide
PMID: 20716873
Journal: Nuklearmedizin. 2010;49 Suppl 1:S41-5.
Title: [Tracers in oncology - preclinical and clinical evaluation].
Author: Krause, B J|Schwarzenbock, S|Schwaiger, M
PMID: 21152689
Journal: Hepatogastroenterology. 2011 Jul-Aug;58(109):1425-30.
Title: A randomized trial of somatostatin to regulate the VEGFs/VEGFRs in patients with gastric cancer.
Author: Zhao, Bin|Yang, Peimin|Yang, Jing|Cai, Duan
PMID: 21937420
Journal: J Exp Clin Cancer Res. 2011 Jan 25;30:13.
Title: The function and mechanism of COX-2 in angiogenesis of gastric cancer cells.
Author: Yao, Liping|Liu, Fei|Hong, Liu|Sun, Li|Liang, Shuhui|Wu, Kaichun|Fan, Daiming
PMID: 21266034
Journal: J Clin Oncol. 2012 Jun 10;30(17):2119-27.
Title: Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a biomarker evaluation from the AVAGAST randomized phase III trial.
Author: Van Cutsem, Eric|de Haas, Sanne|Kang, Yoon-Koo|Ohtsu, Atsushi|Tebbutt, Niall C|Ming Xu, Jian|Peng Yong, Wei|Langer, Bernd|Delmar, Paul|Scherer, Stefan J|Shah, Manish A
PMID: 22565005
Journal: PLoS One. 2012;7(7):e38192.
Title: Role of vascular endothelial growth factor (VEGF) and VEGF-R genotyping in guiding the metastatic process in pT4a resected gastric cancer patients.
Author: Scartozzi, Mario|Loretelli, Cristian|Galizia, Eva|Mandolesi, Alessandra|Pistelli, Mirco|Bittoni, Alessandro|Giampieri, Riccardo|Faloppi, Luca|Bianconi, Maristella|Del Prete, Michela|Bianchi, Francesca|Belvederesi, Laura|Bearzi, Italo|Cascinu, Stefano
PMID: 22808003
Journal: Int J Oncol. 2012 Oct;41(4):1297-304.
Title: Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer.
Author: Masuzawa, Toru|Fujiwara, Yoshiyuki|Okada, Kaoru|Nakamura, Ayumu|Takiguchi, Shuji|Nakajima, Kiyokazu|Miyata, Hiroshi|Yamasaki, Makoto|Kurokawa, Yukinori|Osawa, Ryuji|Takeda, Kazuyoshi|Yoshida, Koji|Tsunoda, Takuya|Nakamura, Yusuke|Mori, Masaki|Doki, Yuichi
PMID: 22842485
Journal: Nucl Med Commun. 2013 Jul;34(7):694-700.
Title: 18F-FLT PET/CT imaging is not competent for the pretreatment evaluation of metastatic gastric cancer: a comparison with 18F-FDG PET/CT imaging.
Author: Zhou, Min|Wang, Chenchen|Hu, Silong|Zhang, Yongping|Yao, Zhifeng|Li, Jin|Guo, Weijian|Zhang, Yingjian
PMID: 23604223
Journal: Contemp Oncol (Pozn). 2013;17(2):165-70.
Title: Evaluation of FLT-PET/CT usefulness in diagnosis and qualification for surgical treatment of gastric cancer.
Author: Staniuk, Tomasz|Zegarski, Wojciech|Malkowski, Bogdan|Jankowski, Michal|Klag, Michal|Pietrzak, Tomasz
PMID: 23788985
Journal: Med Oncol. 2013;30(3):644.
Title: Evidence for angiogenesis-independent contribution of VEGFR1 (FLT1) in gastric cancer recurrence.
Author: Suspitsin, Evgeny N|Kashyap, Aniruddh|Shelekhova, Kseniya V|Sokolenko, Anna P|Kuligina, Ekatherina Sh|Iyevleva, Aglaya G|Kornilov, Alexandr V|Ehemann, Volker|Yanus, Grigoriy A|Aleksakhina, Svetlana N|Preobrazhenskaya, Elena V|Zaitseva, Olga A|Yatsuk, Olga
PMID: 23801279
Journal: Pharmacogenomics. 2013 Dec;14(16):1991-8.
Title: Tumor angiogenesis genotyping and efficacy of first-line chemotherapy in metastatic gastric cancer patients.
Author: Scartozzi, Mario|Giampieri, Riccardo|Loretelli, Cristian|Bittoni, Alessandro|Mandolesi, Alessandra|Faloppi, Luca|Bianconi, Maristella|Del Prete, Michela|Andrikou, Kalliopi|Bearzi, Italo|Cascinu, Stefano
PMID: 24090479
Journal: Gastroenterol Res Pract. 2013;2013:696423.
Title: (18)F-FLT PET/CT in Patients with Gastric Carcinoma.
Author: Malkowski, Bogdan|Staniuk, Tomasz|Srutek, Ewa|Gorycki, Tomasz|Zegarski, Wojciech|Studniarek, Michal
PMID: 24454342
Journal: Int J Oncol. 2014 Mar;44(3):662-8.
Title: Phase I clinical trial of peptide vaccination with URLC10 and VEGFR1 epitope peptides in patients with advanced gastric cancer.
Author: Higashihara, Yoshie|Kato, Junko|Nagahara, Akihito|Izumi, Kentaro|Konishi, Masae|Kodani, Tomohiro|Serizawa, Nobuko|Osada, Taro|Watanabe, Sumio
PMID: 24398900
Journal: J Oncol. 2014;2014:582140.
Title: Disseminated tumor cells in bone marrow of gastric cancer patients: correlation with tumor hypoxia and clinical relevance.
Author: Bubnovskaya, Larissa|Kovelskaya, Antonina|Gumenyuk, Lilya|Ganusevich, Irina|Mamontova, Lesya|Mikhailenko, Victor|Osinsky, Dmitry|Merentsev, Sergej|Osinsky, Sergej
PMID: 24669218
Journal: Am J Cancer Res. 2015 Oct 15;5(11):3301-10. eCollection 2015.
Title: Radiolabeling and evaluation of (64)Cu-DOTA-F56 peptide targeting vascular endothelial growth factor receptor 1 in the molecular imaging of gastric cancer.
Author: Zhu, Hua|Zhao, Chuanke|Liu, Fei|Wang, Lixin|Feng, Junnan|Zhou, Zheng|Qu, Like|Shou, Chengchao|Yang, Zhi
PMID: 26807312
Journal: Am J Transl Res. 2015 Aug 15;7(8):1429-39. eCollection 2015.
Title: Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes.
Author: Li, Shu-Chun|Ma, Rong|Wu, Jian-Zhong|Xiao, Xia|Wu, Wei|Li, Gang|Chen, Bo|Sharma, Ashok|Bai, Shan|Dun, Bo-Ying|She, Jin-Xiong|Tang, Jin-Hai
PMID: 26396673
Journal: Abdom Radiol (NY). 2016 Jul;41(7):1349-56.
Title: Comparison of FLT-PET/CT and CECT in gastric cancer diagnosis.
Author: Staniuk, Tomasz|Malkowski, Bogdan|Srutek, Ewa|Szlezak, Przemyslaw|Zegarski, Wojciech
PMID: 26826089
Journal: Oncol Lett. 2016 Feb;11(2):1043-1050.
Title: Interleukin-8: A potent promoter of angiogenesis in gastric cancer.
Author: Shi, Jun|Wei, Pin-Kang
PMID: 26893688
Journal: Br J Cancer. 2016 Oct 11;115(8):974-982.
Title: Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab.
Author: Fuchs, Charles S|Tabernero, Josep|Tomasek, Jiri|Chau, Ian|Melichar, Bohuslav|Safran, Howard|Tehfe, Mustapha A|Filip, Dumitru|Topuzov, Eldar|Schlittler, Luis|Udrea, Anghel Adrian|Campbell, William|Brincat, Stephen|Emig, Michael|Melemed, Symantha A|Hozak, R
PMID: 27623234
Journal: EJNMMI Res. 2016 Dec;6(1):81.
Title: Evaluation of (18)F-fluorothymidine positron emission tomography ([(18)F]FLT-PET/CT) methodology in assessing early response to chemotherapy in patients with gastro-oesophageal cancer.
Author: Sharma, R|Mapelli, P|Hanna, G B|Goldin, R|Power, D|Al-Nahhas, A|Merchant, S|Ramaswami, R|Challapalli, A|Barwick, T|Aboagye, E O
PMID: 27854031
Journal: Am J Transl Res. 2016 Dec 15;8(12):5729-5740. eCollection 2016.
Title: Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers.
Author: Wu, Jianzhong|Li, Shuchun|Ma, Rong|Sharma, Ashok|Bai, Shan|Dun, Boying|Cao, Haixia|Jing, Changwen|She, Jinxiong|Feng, Jifeng
PMID: 28078044
Journal: ACS Med Chem Lett. 2017 Jan 20;8(2):266-269.
Title: (125)I-F56 Peptide as Radioanalysis Agent Targeting VEGFR1 in Mice Xenografted with Human Gastric Tumor.
Author: Zhu, Hua|Zhao, Chuanke|Liu, Fei|Wang, Lixin|Feng, Junnan|Shou, Chengchao|Yang, Zhi
PMID: 28197324
Journal: Int J Oncol. 2017 May;50(5):1655-1662.
Title: Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Author: Fujiwara, Yoshiyuki|Okada, Kaoru|Omori, Takeshi|Sugimura, Keijiro|Miyata, Hiroshi|Ohue, Masayuki|Kobayashi, Shogo|Takahashi, Hidenori|Nakano, Hiroyuki|Mochizuki, Chie|Shimizu, Katsuji|Yano, Masahiko|Nakamura, Yusuke|Mori, Masaki|Doki, Yuichiro
PMID: 28393243
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: Theranostics. 2018 Mar 7;8(8):2094-2106.
Title: Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy.
Author: Feng, Junnan|Zhao, Chuanke|Wang, Lixin|Qu, Like|Zhu, Hua|Yang, Zhi|An, Guo|Tian, Huifang|Shou, Chengchao
PMID: 29721065
Journal: Int J Oncol. 2018 Aug;53(2):737-749.
Title: Colony-stimulating factor-1 and colony-stimulating factor-1 receptor co-expression is associated with disease progression in gastric cancer.
Author: Okugawa, Yoshinaga|Toiyama, Yuji|Ichikawa, Takashi|Kawamura, Mikio|Yasuda, Hiromi|Fujikawa, Hiroyuki|Saigusa, Susumu|Ohi, Masaki|Araki, Toshimitsu|Tanaka, Koji|Inoue, Yasuhiro|Tanaka, Motoyoshi|Miki, Chikao|Kusunoki, Masato
PMID: 29767252
Journal: Br J Radiol. 2018 Sep;91(1089):20180259.
Title: Imaging peritoneal metastasis of gastric cancer with (18)F-fluorothymidine positron emission tomography/computed tomography: a proof-of-concept study.
Author: Honma, Yoshitaka|Terauchi, Takashi|Tateishi, Ukihide|Kano, Daisuke|Nagashima, Kengo|Shoji, Hirokazu|Iwasa, Satoru|Takashima, Atsuo|Kato, Ken|Hamaguchi, Tetsuya|Boku, Narikazu|Shimada, Yasuhiro|Yamada, Yasuhide
PMID: 29916721