Primary Site >> Colorectal Cancer

Gene >> FLT1

Journal: Cancer Res. 1993 Oct 1;53(19):4727-35.
Title: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract.
Author: Brown, L F|Berse, B|Jackman, R W|Tognazzi, K|Manseau, E J|Senger, D R|Dvorak, H F
PMID: 8402650
Journal: J Clin Invest. 1995 Apr;95(4):1789-97.
Title: Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis.
Author: Warren, R S|Yuan, H|Matli, M R|Gillett, N A|Ferrara, N
PMID: 7535799
Journal: Cancer Res. 1995 Sep 15;55(18):3964-8.
Title: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer.
Author: Takahashi, Y|Kitadai, Y|Bucana, C D|Cleary, K R|Ellis, L M
PMID: 7664263
Journal: Pathobiology. 1998;66(5):247-52.
Title: Regulation of vascular endothelial growth factor receptor KDR in vitro by a soluble factor in confluent endothelial cells.
Author: Liu, W|Ellis, L M
PMID: 9732240
Journal: Am J Gastroenterol. 1999 Apr;94(4):1070-6.
Title: Increased expression of angiogenic factors in human colonic angiodysplasia.
Author: Junquera, F|Saperas, E|de Torres, I|Vidal, M T|Malagelada, J R
PMID: 10201485
Journal: Cell Res. 1999 Mar;9(1):11-25.
Title: A novel gene delivery system targeting cells expressing VEGF receptors.
Author: Li, J M|Han, J S|Huang, Y|Tain, P K|Qu, S M|Yao, M|Jiang, H Q|Wan, D F|Luo, J C|Gu, C X|Gu, J R
PMID: 10321685
Journal: Int J Cancer. 2000 Apr 15;86(2):174-81.
Title: Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa.
Author: Andre, T|Kotelevets, L|Vaillant, J C|Coudray, A M|Weber, L|Prevot, S|Parc, R|Gespach, C|Chastre, E
PMID: 10738243
Journal: Dis Colon Rectum. 2000 Jul;43(7):980-6.
Title: Angiogenesis of liver metastases: role of sinusoidal endothelial cells.
Author: Gervaz, P|Scholl, B|Mainguene, C|Poitry, S|Gillet, M|Wexner, S
PMID: 10910247
Journal: Oncogene. 2002 Apr 25;21(18):2896-900.
Title: Enhanced expression of vascular endothelial growth factor (VEGF) plays a critical role in the tumor progression potential induced by simian virus 40 large T antigen.
Author: Catalano, Alfonso|Romano, Mario|Martinotti, Stefano|Procopio, Antonio
PMID: 11973650
Journal: Anticancer Res. 2002 May-Jun;22(3):1877-80.
Title: Soluble FLT-1 is detectable in the sera of colorectal and breast cancer patients.
Author: Kumar, Harish|Heer, Kamal|Greenman, John|Kerin, Michael J|Monson, John R T
PMID: 12168886
Journal: Eur J Nucl Med Mol Imaging. 2003 Jul;30(7):988-94.
Title: Potential impact of [18F]3'-deoxy-3'-fluorothymidine versus [18F]fluoro-2-deoxy-D-glucose in positron emission tomography for colorectal cancer.
Author: Francis, D L|Visvikis, D|Costa, D C|Arulampalam, T H A|Townsend, C|Luthra, S K|Taylor, I|Ell, P J
PMID: 12739071
Journal: J Pathol. 2003 Jun;200(2):183-94.
Title: The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression.
Author: Hanrahan, Vickie|Currie, Margaret J|Gunningham, Sarah P|Morrin, Helen R|Scott, Prudence A E|Robinson, Bridget A|Fox, Stephen B
PMID: 12754739
Journal: Curr Biol. 2003 Sep 30;13(19):1721-7.
Title: Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids.
Author: Bates, Richard C|Goldsmith, Jeffrey D|Bachelder, Robin E|Brown, Courtney|Shibuya, Masabumi|Oettgen, Peter|Mercurio, Arthur M
PMID: 14521839
Journal: Cancer Res. 2003 Sep 15;63(18):5978-91.
Title: CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.
Author: Ruggeri, Bruce|Singh, Jasbir|Gingrich, Diane|Angeles, Thelma|Albom, Mark|Yang, Shi|Chang, Hong|Robinson, Candy|Hunter, Kathryn|Dobrzanski, Pawel|Jones-Bolin, Susan|Pritchard, Sonya|Aimone, Lisa|Klein-Szanto, Andres|Herbert, Jean-Marc|Bono, Francoise|Schae
PMID: 14522925
Journal: Gut. 2003 Nov;52(11):1602-6.
Title: In vivo imaging of cellular proliferation in colorectal cancer using positron emission tomography.
Author: Francis, D L|Freeman, A|Visvikis, D|Costa, D C|Luthra, S K|Novelli, M|Taylor, I|Ell, P J
PMID: 14570730
Journal: Anticancer Res. 2004 Jul-Aug;24(4):2353-7.
Title: Changes in serum soluble VEGFR-1 and Tie-2 receptors in colorectal cancer patients following surgical resections.
Author: Chin, Kin-Fah|Greenman, John|Reusch, Petra|Gardiner, Eric|Marme, Dieter|Monson, John
PMID: 15330184
Journal: Oncol Res. 2004;14(11-12):611-5.
Title: Concentrations of VEGF and VEGFR1 in paired tumor arteries and veins in patients with rectal cancer.
Author: Svendsen, Mads N|Lykke, Jakob|Werther, Kim|Christensen, Ib J|Nielsen, Hans J
PMID: 15667002
Journal:
Title: (125)I-Vascular endothelial growth factor-121
Author: Leung, Kam
PMID: 20641207
Journal:
Title: (111)In-Diethylenetriamine pentaacetic acid-bevacizumab
Author: Leung, Kam
PMID: 20641545
Journal:
Title: Alexa Fluor 680-Bevacizumab
Author: Leung, Kam
PMID: 20641728
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-quantum dot-vascular endothelial growth factor
Author: Zhang, Huiming
PMID: 20641777
Journal:
Title: (89)Zr-N-Succinyldesferrioxamine-bevacizumab
Author: Leung, Kam
PMID: 20641842
Journal:
Title: (86)Y-CHX-A''-Diethylenetriamine pentaacetic acid-bevacizumab
Author: Leung, Kam
PMID: 21433411
Journal:
Title: Anti-vascular endothelial growth factor polylactic acid-polyethylene glycol-poly-L-Lys/gadolinium-diethylenetriamine pentaacetic acid nanoparticles
Author: Leung, Kam
PMID: 22812022
Journal:
Title: (64)Cu-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-bevacizumab-IRDye 800CW
Author: Leung, Kam
PMID: 23534080
Journal: Cancer Res. 2005 Jan 1;65(1):195-202.
Title: Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -- and vascular endothelial growth factor-mediated cellular invasion and tumor growth.
Author: Rivat, Christine|Rodrigues, Sylvie|Bruyneel, Erik|Pietu, Genevieve|Robert, Amelie|Redeuilh, Gerard|Bracke, Marc|Gespach, Christian|Attoub, Samir
PMID: 15665295
Journal: Oncogene. 2005 Apr 14;24(16):2647-53.
Title: Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells.
Author: Fan, Fan|Wey, Jane S|McCarty, Marya F|Belcheva, Anna|Liu, Wenbiao|Bauer, Todd W|Somcio, Ray J|Wu, Yan|Hooper, Andrea|Hicklin, Daniel J|Ellis, Lee M
PMID: 15735759
Journal: Mol Ther. 2005 Apr;11(4):553-62.
Title: Suppression of tumor growth by oncolytic adenovirus-mediated delivery of an antiangiogenic gene, soluble Flt-1.
Author: Zhang, Zilai|Zou, Weiguo|Wang, Jinhui|Gu, Jinfa|Dang, Yunkun|Li, Binghua|Zhao, Lili|Qian, Cheng|Qian, Qijun|Liu, Xinyuan
PMID: 15771958
Journal: Cancer Biol Ther. 2005 Apr;4(4):365-70. Epub 2005 Apr 4.
Title: The epithelial-mesenchymal transition (EMT) and colorectal cancer progression.
Author: Bates, Richard C|Mercurio, Arthur M
PMID: 15846061
Journal: J Surg Res. 2005 Sep;128(1):140-6.
Title: Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation.
Author: Yang, Shung-Haur|Lin, Jen-Kou|Huang, Chi-Jung|Chen, Wei-Shone|Li, Shih-Yun|Chiu, Jen-Hwey
PMID: 15993897
Journal: Am J Respir Cell Mol Biol. 2005 Dec;33(6):629-35. Epub 2005 Sep 8.
Title: Gene transfer of the vascular endothelial growth factor receptor flt-1 suppresses pulmonary metastasis associated with lung growth.
Author: Mae, Masahiro|O'Connor, Timothy P|Crystal, Ronald G
PMID: 16151052
Journal: Virchows Arch. 2006 Feb;448(2):127-34. Epub 2005 Sep 22.
Title: Endoglin (CD105) expression in angiogenesis of colon cancer: analysis using tissue microarrays and comparison with other endothelial markers.
Author: Minhajat, Rahmawati|Mori, Daisuke|Yamasaki, Fumio|Sugita, Yasuo|Satoh, Toshimi|Tokunaga, Osamu
PMID: 16177881
Journal: Br J Cancer. 2006 Jun 5;94(11):1710-7.
Title: Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases.
Author: Lesslie, D P|Summy, J M|Parikh, N U|Fan, F|Trevino, J G|Sawyer, T K|Metcalf, C A|Shakespeare, W C|Hicklin, D J|Ellis, L M|Gallick, G E
PMID: 16685275
Journal: Cancer Res. 2006 Aug 1;66(15):7621-9.
Title: In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.
Author: Leyton, Julius|Alao, John P|Da Costa, Marco|Stavropoulou, Alexandra V|Latigo, John R|Perumal, Meg|Pillai, Radhakrishna|He, Qimin|Atadja, Peter|Lam, Eric W-F|Workman, Paul|Vigushin, David M|Aboagye, Eric O
PMID: 16885362
Journal: Mol Cancer Ther. 2006 Aug;5(8):2070-7.
Title: Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts.
Author: Nguyen, Quang-De|Rodrigues, Sylvie|Rodrigue, Christelle M|Rivat, Christine|Grijelmo, Clara|Bruyneel, Erik|Emami, Shahin|Attoub, Samir|Gespach, Christian
PMID: 16928828
Journal: Pathol Int. 2006 Dec;56(12):717-23.
Title: Organ-specific endoglin (CD105) expression in the angiogenesis of human cancers.
Author: Minhajat, Rahmawati|Mori, Daisuke|Yamasaki, Fumio|Sugita, Yasuo|Satoh, Toshimi|Tokunaga, Osamu
PMID: 17096728
Journal: Nucl Med Biol. 2006 Nov;33(8):963-9.
Title: Radioiodinated VEGF to image tumor angiogenesis in a LS180 tumor xenograft model.
Author: Yoshimoto, Mitsuyoshi|Kinuya, Seigo|Kawashima, Atsuhiro|Nishii, Ryuichi|Yokoyama, Kunihiko|Kawai, Keiichi
PMID: 17127168
Journal: Cancer Metastasis Rev. 2006 Dec;25(4):521-9.
Title: Bone marrow cells in the 'pre-metastatic niche': within bone and beyond.
Author: Kaplan, Rosandra N|Psaila, Bethan|Lyden, David
PMID: 17186383
Journal: Gan To Kagaku Ryoho. 2006 Nov;33(12):1841-4.
Title: [The relationship between plasma level of VEGF or soluble Flt-1 and efficacy of hepatic arterial chemotherapy in patients with liver metastasis of colorectal cancer].
Author: Gonda, Tsuyoshi|Okada, Norimichi|Nakada, Hiroshi|Yokoyama, Masaru|Miyazaki, Tatsuya|Ishibashi, Keiichiro|Ishida, Hideyuki|Matsumoto, Yoshiro|Miura, Tsuyoshi
PMID: 17212123
Journal: Cancer Res. 2007 Apr 1;67(7):3286-94.
Title: Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells.
Author: Abdelrahim, Maen|Baker, Cheryl H|Abbruzzese, James L|Sheikh-Hamad, David|Liu, Shengxi|Cho, Sung Dae|Yoon, Kyungsil|Safe, Stephen
PMID: 17409437
Journal: Eur J Surg Oncol. 2007 Dec;33(10):1169-76. Epub 2007 May 18.
Title: Perioperative sargramostim (recombinant human GM-CSF) induces an increase in the level of soluble VEGFR1 in colon cancer patients undergoing minimally invasive surgery.
Author: Kirman, I|Belizon, A|Balik, E|Feingold, D|Arnell, T|Horst, P|Kumara, S|Cekic, V|Jain, S|Nasar, A|Whelan, R L
PMID: 17512160
Journal: Pharmacogenomics. 2007 Dec;8(12):1705-13.
Title: Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients.
Author: Azuma, Mizutomo|Shi, Michael|Danenberg, Kathleen D|Gardner, Humphrey|Barrett, Carl|Jacques, Christian J|Sherod, Andrew|Iqbal, Syma|El-Khoueiry, Anthony|Yang, Dongyun|Zhang, Wu|Danenberg, Peter V|Lenz, Heinz-Josef
PMID: 18086000
Journal: Cancer Res. 2008 Jan 1;68(1):285-91.
Title: Differential involvement of vascular endothelial growth factor in the survival of hypoxic colon cancer cells.
Author: Calvani, Maura|Trisciuoglio, Daniela|Bergamaschi, Cristina|Shoemaker, Robert H|Melillo, Giovanni
PMID: 18172321
Journal: J Natl Cancer Inst. 2008 Jan 16;100(2):109-20.
Title: Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver.
Author: Gray, Michael J|Van Buren, George|Dallas, Nikolaos A|Xia, Ling|Wang, Xuemei|Yang, Anthony D|Somcio, Ray J|Lin, Yvonne G|Lim, Sherry|Fan, Fan|Mangala, Lingegowda S|Arumugam, Thiruvengadam|Logsdon, Craig D|Lopez-Berestein, Gabriel|Sood, Anil K|Ellis, Lee M
PMID: 18182619
Journal: Ann Surg Oncol. 2008 Apr;15(4):1232-8.
Title: Messenger RNA expression of vascular endothelial growth factor and its receptors in primary colorectal cancer and corresponding liver metastasis.
Author: Kobayashi, Hirotoshi|Sugihara, Kenichi|Uetake, Hiroyuki|Higuchi, Tetsuro|Yasuno, Masamichi|Enomoto, Masayuki|Kuramochi, Hidekazu|Lenz, Heinz-Josef|Danenberg, Kathleen D|Danenberg, Peter V
PMID: 18239970
Journal: J Surg Res. 2008 Aug;148(2):158-63.
Title: Hepatic ischemia-reperfusion increases vascular endothelial growth factor and cancer growth in rats.
Author: Tamagawa, Koji|Horiuchi, Tetsuya|Uchinami, Masaru|Doi, Koji|Yoshida, Makoto|Nakamura, Tomoaki|Sasaki, Hisashi|Taniguchi, Masanobu|Tanaka, Kuniyoshi
PMID: 18468635
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2008 May;28(5):696-9.
Title: [Role of vascular endothelial growth factor receptor 1-positive hematopoietic progenitor cell clusters in human colorectal carcinoma metastasis].
Author: Yang, Zhao-hui|Yang, Min|Xiong, Han-zhen|Li, Xue-nong
PMID: 18504182
Journal: Hum Pathol. 2008 Oct;39(10):1483-94.
Title: Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.
Author: Furlan, Daniela|Sahnane, Nora|Carnevali, Ileana|Cerutti, Roberta|Bertoni, Francesco|Kwee, Ivo|Uccella, Silvia|Bertolini, Valentina|Chiaravalli, Anna Maria|Capella, Carlo
PMID: 18619649
Journal: Mol Cancer Ther. 2008 Sep;7(9):3064-70.
Title: Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells.
Author: Fan, Fan|Gray, Michael J|Dallas, Nikolaos A|Yang, Anthony D|Van Buren, George 2nd|Camp, E Ramsay|Ellis, Lee M
PMID: 18790786
Journal: Mol Cancer Ther. 2008 Sep;7(9):3112-21.
Title: Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901.
Author: Leyton, Julius|Smith, Graham|Lees, Mark|Perumal, Meg|Nguyen, Quang-de|Aigbirhio, Franklin I|Golovko, Oksana|He, Quimin|Workman, Paul|Aboagye, Eric O
PMID: 18790789
Journal: Oncol Rep. 2009 Apr;21(4):933-9.
Title: Comparative study of human colonic tumor-derived endothelial cells (HCTEC) and normal colonic microvascular endothelial cells (HCMEC): Hypoxia-induced sVEGFR-1 and sVEGFR-2 levels.
Author: Jayasinghe, Caren|Simiantonaki, Nektaria|Michel-Schmidt, Romi|Kirkpatrick, Charles James
PMID: 19287991
Journal: Int J Cancer. 2009 Oct 15;125(8):1965-74.
Title: Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Abdelrahim, Maen|Abudayyeh, Ala|Jutooru, Indira|Chadalapaka, Gayathri|Wu, Fei|Mertens-Talcott, Susanne|Vanderlaag, Kathy|Cho, Sung Dae|Smith, Roger 3rd|Safe, Stephen
PMID: 19582879
Journal: Epigenetics. 2009 Jul 1;4(5):313-21. Epub 2009 Jul 3.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Hwang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 19633424
Journal: BioDrugs. 2009;23(5):289-304.
Title: Monoclonal antibodies targeting vascular endothelial growth factor: current status and future challenges in cancer therapy.
Author: Hsu, Jerry Y|Wakelee, Heather A
PMID: 19754219
Journal: J Nucl Med. 2009 Nov;50(11):1857-64.
Title: Using dual-tracer PET to predict the biologic behavior of human colorectal cancer.
Author: Wang, Hui|Zhang, Jinming|Tian, Jiahe|Qu, Baolin|Li, Tianran|Chen, Yingmao|Liu, Jian|Wang, Shan
PMID: 19837754
Journal: Mol Cancer Ther. 2009 Nov;8(11):3130-9.
Title: Experimental cancer therapy using restoration of NAD+ -linked 15-hydroxyprostaglandin dehydrogenase expression.
Author: Kaliberova, Lyudmila N|Kusmartsev, Sergei A|Krendelchtchikova, Valentina|Stockard, Cecil R|Grizzle, William E|Buchsbaum, Donald J|Kaliberov, Sergey A
PMID: 19887544
Journal: Clin Cancer Res. 2009 Dec 15;15(24):7529-7537.
Title: Vascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant {beta}-Catenin Activation in Colon Cancer.
Author: Naik, Snehal|Dothager, Robin S|Marasa, Jayne|Lewis, Cory L|Piwnica-Worms, David
PMID: 20008853
Journal: PLoS One. 2009 Dec 21;4(12):e8357.
Title: Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.
Author: Hinoue, Toshinori|Weisenberger, Daniel J|Pan, Fei|Campan, Mihaela|Kim, Myungjin|Young, Joanne|Whitehall, Vicki L|Leggett, Barbara A|Laird, Peter W
PMID: 20027224
Journal: Epigenetics. 2009 Jul 1;4(5):313-321.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Whang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 28001118
Journal: Surg Endosc. 2010 Feb;24(2):283-9.
Title: Minimally invasive colon resection for malignant colonic conditions is associated with a transient early increase in plasma sVEGFR1 and a decrease in sVEGFR2 levels after surgery.
Author: Shantha Kumara, H M C|Cabot, J C|Hoffman, A|Luchtefeld, M|Kalady, M F|Hyman, N|Feingold, D|Baxter, R|Whelan, R L
PMID: 19551437
Journal: Int J Colorectal Dis. 2010 Feb;25(2):181-6.
Title: K-ras mutation status correlates with the expression of VEGFR1, VEGFR2, and PDGFRalpha in colorectal cancer.
Author: Schimanski, Carl C|Zimmermann, Tim|Schmidtmann, Irene|Gockel, Ines|Lang, Hauke|Galle, Peter R|Moehler, Markus|Berger, Martin R
PMID: 19936766
Journal: World J Gastroenterol. 2010 Mar 7;16(9):1086-92.
Title: Blocking effects of siRNA on VEGF expression in human colorectal cancer cells.
Author: Yin, Yu|Cao, Li-Yu|Wu, Wen-Qing|Li, Hao|Jiang, Yan|Zhang, Hong-Fu
PMID: 20205278
Journal: BMC Cancer. 2010 Mar 11;10:93.
Title: Role of the VEGF ligand to receptor ratio in the progression of mismatch repair-proficient colorectal cancer.
Author: Eppenberger, Manuela|Zlobec, Inti|Baumhoer, Daniel|Terracciano, Luigi|Lugli, Alessandro
PMID: 20222950
Journal: IDrugs. 2010 Sep;13(9):636-45.
Title: Tivozanib, a pan-VEGFR tyrosine kinase inhibitor for the potential treatment of solid tumors.
Author: De Luca, Antonella|Normanno, Nicola
PMID: 20799147
Journal: Scand J Clin Lab Invest. 2010 Nov;70(7):503-11.
Title: Biological variations in plasma VEGF and VEGFR-1 may compromise their biomarker value in colorectal cancer.
Author: Svendsen, Mads N|Brunner, Nils|Christensen, Ib J|Ytting, Henriette|Bentsen, Camilla|Lomholt, Anne F|Nielsen, Hans J
PMID: 20873967
Journal: Cancer Res. 2010 Nov 1;70(21):8357-67.
Title: Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment.
Author: Lee, Yoon-Jin|Karl, Daniel L|Maduekwe, Ugwuji N|Rothrock, Courtney|Ryeom, Sandra|D'Amore, Patricia A|Yoon, Sam S
PMID: 20978198
Journal: Nuklearmedizin. 2010;49 Suppl 1:S41-5.
Title: [Tracers in oncology - preclinical and clinical evaluation].
Author: Krause, B J|Schwarzenbock, S|Schwaiger, M
PMID: 21152689
Journal: Oncol Lett. 2010 Mar;1(2):253-259.
Title: Association of plasma VEGF-A, soluble VEGFR-1 and VEGFR-2 levels and clinical response and survival in advanced colorectal cancer patients receiving bevacizumab with modified FOLFOX6.
Author: Aoyagi, Yoshiko|Iinuma, Hisae|Horiuchi, Atsushi|Shimada, Ryu|Watanabe, Toshiaki
PMID: 22966290
Journal: Biochem Pharmacol. 2011 Feb 1;81(3):379-87.
Title: Prostaglandin E(2) regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells.
Author: Fujino, Hiromichi|Toyomura, Kaori|Chen, Xiao-bo|Regan, John W|Murayama, Toshihiko
PMID: 21070749
Journal: Mol Cancer Res. 2011 Feb;9(2):195-202.
Title: GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway.
Author: Pathi, Satya S|Jutooru, Indira|Chadalapaka, Gayathri|Sreevalsan, Sandeep|Anand, S|Thatcher, Gregory Rj|Safe, Stephen
PMID: 21156786
Journal: Mol Cancer Ther. 2011 Mar;10(3):404-15.
Title: sFLT01: a novel fusion protein with antiangiogenic activity.
Author: Bagley, Rebecca G|Kurtzberg, Leslie|Weber, William|Nguyen, Tri-Hung|Roth, Stephanie|Krumbholz, Roy|Yao, Min|Richards, Brenda|Zhang, Mindy|Pechan, Peter|Schmid, Steve|Scaria, Abraham|Kaplan, Johanne|Teicher, Beverly A
PMID: 21252283
Journal: Radiother Oncol. 2011 Mar;98(3):357-9.
Title: 18F-FLT-PET for detection of rectal cancer.
Author: Muijs, Christina T|Beukema, Jannet C|Widder, Joachim|van den Bergh, Alphons C M|Havenga, Klaas|Pruim, Jan|Langendijk, Johannes A
PMID: 21295872
Journal: Br J Cancer. 2011 Apr 12;104(8):1270-7.
Title: Chronic exposure of colorectal cancer cells to bevacizumab promotes compensatory pathways that mediate tumour cell migration.
Author: Fan, F|Samuel, S|Gaur, P|Lu, J|Dallas, N A|Xia, L|Bose, D|Ramachandran, V|Ellis, L M
PMID: 21407219
Journal: Anticancer Res. 2011 Mar;31(3):843-7.
Title: Co-localization of prothrombin fragment F1+2 and VEGF-R2-bound VEGF in human colon cancer.
Author: Sierko, Ewa|Wojtukiewicz, Marek Z|Zimnoch, Lech|Thorpe, Philip E|Brekken, Rolf A|Kisiel, Walter
PMID: 21498704
Journal: Clin Cancer Res. 2011 May 15;17(10):3469-77.
Title: Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Author: Grimminger, Peter P|Danenberg, Peter|Dellas, Kathrin|Arnold, Dirk|Rodel, Claus|Machiels, Jean-Pascal|Haustermans, Karin|Debucquoy, Annelies|Velenik, Vaneja|Sempoux, Christine|Bracko, Matej|Holscher, Arnulf H|Semrau, Robert|Yang, Dongyun|Danenberg, Kathlee
PMID: 21558395
Journal: J Biomed Biotechnol. 2011;2011:535902.
Title: Early detection of tumor response by FLT/microPET Imaging in a C26 murine colon carcinoma solid tumor animal model.
Author: Lee, Wan-Chi|Chang, Chih-Hsien|Ho, Chung-Li|Chen, Liang-Cheng|Wu, Yu-Hsien|Chen, Jenn-Tzong|Wang, Ying-Ling|Lee, Te-Wei
PMID: 21869861
Journal: Clin Cancer Res. 2011 Oct 15;17(20):6522-30.
Title: EGFR- and VEGF(R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies.
Author: Poindessous, Virginie|Ouaret, Djamila|El Ouadrani, Karima|Battistella, Aude|Megalophonos, Virginie F|Kamsu-Kom, Nyam|Petitprez, Amelie|Escargueil, Alexandre E|Boudou, Pascaline|Dumont, Sylvie|Cervera, Pascale|Flejou, Jean-Francois|Andre, Thierry|Tournigan
PMID: 21880790
Journal: Nutr Cancer. 2011;63(7):1133-42.
Title: Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells.
Author: Pathi, Satya S|Lei, Ping|Sreevalsan, Sandeep|Chadalapaka, Gayathri|Jutooru, Indira|Safe, Stephen
PMID: 21919647
Journal: PLoS One. 2011;6(12):e28841.
Title: Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors.
Author: Morgillo, Floriana|Martinelli, Erika|Troiani, Teresa|Orditura, Michele|De Vita, Ferdinando|Ciardiello, Fortunato
PMID: 22174910
Journal: Hum Exp Toxicol. 2012 Feb;31(2):117-25.
Title: The relationship among acute-phase responce proteins, cytokines, and hormones in various gastrointestinal cancer types patients with cachectic.
Author: Kemik, Ozgur|Kemik, A S|Begenik, H|Erdur, F M|Emre, H|Sumer, A|Purisa, S|Tuzun, S|Kotan, C
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Journal: Clin Cancer Res. 2012 Jan 15;18(2):454-64.
Title: Targeting tumor-associated endothelial cells: anti-VEGFR2 immunoliposomes mediate tumor vessel disruption and inhibit tumor growth.
Author: Wicki, Andreas|Rochlitz, Christoph|Orleth, Annette|Ritschard, Reto|Albrecht, Imke|Herrmann, Richard|Christofori, Gerhard|Mamot, Christoph
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Journal: Mol Imaging Biol. 2012 Oct;14(5):617-24.
Title: Pharmacodynamic evaluation of irinotecan therapy by FDG and FLT PET/CT imaging in a colorectal cancer xenograft model.
Author: Mudd, Sarah R|Holich, Kimberley D|Voorbach, Martin J|Cole, Todd B|Reuter, David R|Tapang, Paul|Bukofzer, Gail|Chakravartty, Arunava|Donawho, Cherrie K|Palma, Joann P|Fox, Gerard B|Day, Mark|Luo, Yanping
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Journal: Clin Cancer Res. 2012 Feb 1;18(3):688-99.
Title: Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment.
Author: Vermaat, Joost S|Nijman, Isaac J|Koudijs, Marco J|Gerritse, Frank L|Scherer, Stefan J|Mokry, Michal|Roessingh, Wijnand M|Lansu, Nico|de Bruijn, Ewart|van Hillegersberg, Richard|van Diest, Paul J|Cuppen, Edwin|Voest, Emile E
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Journal: Mol Ther. 2012 May;20(5):938-47.
Title: Soluble vascular endothelial growth factor decoy receptor FP3 exerts potent antiangiogenic effects.
Author: Yu, De-Chao|Lee, Jung-Sun|Yoo, Ji Young|Shin, Hyewon|Deng, Hongxin|Wei, Yuquan|Yun, Chae-Ok
PMID: 22273580
Journal: Clin Cancer Res. 2012 May 1;18(9):2658-67.
Title: A phase I dose-escalation study of regorafenib (BAY 73-4506), an inhibitor of oncogenic, angiogenic, and stromal kinases, in patients with advanced solid tumors.
Author: Mross, Klaus|Frost, Annette|Steinbild, Simone|Hedbom, Susanne|Buchert, Martin|Fasol, Ulrike|Unger, Clemens|Kratzschmar, Jorn|Heinig, Roland|Boix, Oliver|Christensen, Olaf
PMID: 22421192
Journal: J Nucl Med. 2012 May;53(5):823-30.
Title: Oxygen breathing affects 3'-deoxy-3'-18F-fluorothymidine uptake in mouse models of arthritis and cancer.
Author: Fuchs, Kerstin|Kukuk, Damaris|Reischl, Gerald|Foller, Michael|Eichner, Martin|Reutershan, Jorg|Lang, Florian|Rocken, Martin|Pichler, Bernd J|Kneilling, Manfred
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Journal: Int J Mol Med. 2012 Jul;30(1):126-32.
Title: Antitumor effect of FP3 in combination with cetuximab on patient-derived tumor tissue xenograft models of primary colon carcinoma and related lymphatic and hepatic metastases.
Author: Dong, Xiaofang|Jin, Ketao|Hu, Xiaoyan|Du, Fangmin|Lan, Huanrong|Han, Na|Ma, Zhaosheng|Xie, Bojian|Cui, Binbin|Teng, Lisong|Cao, Feilin
PMID: 22505231
Journal: Nuklearmedizin. 2012;51(5):163-9.
Title: 18F-FLT and 125I-IdUrd uptake increase in human tumour cell lines induced by the thymidylate synthase inhibitor FdUrd.
Author: Viertl, D|Perillo-Adamer, F|Andre, P-A|Ametamey, S M|Ross, T L|Kosinski, M|Dupertuis, Y M|Bischof Delaloye, A|Buchegger, F
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Journal: Expert Opin Investig Drugs. 2012 Jun;21(6):879-89.
Title: Regorafenib for cancer.
Author: Strumberg, Dirk|Schultheis, Beate
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Journal: Cancer Biol Ther. 2012 Jul;13(9):737-44.
Title: Antitumor effects of FP3 in combination with capecitabine on PDTT xenograft models of primary colon carcinoma and related lymphatic and hepatic metastases.
Author: Jin, Ketao|Lan, Huanrong|Xie, Bojian|He, Kuifeng|Xu, Zhenzhen|Li, Guangliang|Han, Na|Teng, Lisong|Cao, Feilin
PMID: 22617773
Journal: Nucl Med Biol. 2012 Oct;39(7):962-9.
Title: New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts.
Author: Persson, Morten|Rasmussen, Palle|Madsen, Jacob|Ploug, Michael|Kjaer, Andreas
PMID: 22739362
Journal: Tokai J Exp Clin Med. 2012 Jul 20;37(2):57-61.
Title: Significant clinical response of advanced colon cancer to peptide vaccine therapy: a case report.
Author: Yasuda, Seiei|Tsuchiya, Izumi|Okada, Kazutake|Tanaka, Akira|Suzuki, Toshiyuki|Sadahiro, Sotaro|Takeda, Kazuyoshi|Yamamoto, Soichiro|Nakui, Minoru
PMID: 22763829
Journal: Life Sci. 2012 Oct 5;91(11-12):429-39.
Title: D-limonene rich volatile oil from blood oranges inhibits angiogenesis, metastasis and cell death in human colon cancer cells.
Author: Chidambara Murthy, Kotamballi N|Jayaprakasha, Guddadarangavvanahally K|Patil, Bhimanagouda S
PMID: 22935404
Journal: BMC Complement Altern Med. 2012 Sep 19;12:160.
Title: Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells.
Author: Law, Pui-Ching|Auyeung, Kathy K|Chan, Lok-Yi|Ko, Joshua K
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Journal: Cell Death Dis. 2012 Oct 11;3:e406.
Title: A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation.
Author: Zhang, Y M|Dai, B L|Zheng, L|Zhan, Y Z|Zhang, J|Smith, W W|Wang, X L|Chen, Y N|He, L C
PMID: 23059825
Journal: PLoS One. 2012;7(10):e48208.
Title: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors.
Author: Pathi, Satya|Jutooru, Indira|Chadalapaka, Gayathri|Nair, Vijayalekshmi|Lee, Syng-Ook|Safe, Stephen
PMID: 23110215
Journal: PLoS One. 2012;7(11):e50618.
Title: [18F]FLT PET for non-invasive assessment of tumor sensitivity to chemotherapy: studies with experimental chemotherapy TP202377 in human cancer xenografts in mice.
Author: Munk Jensen, Mette|Erichsen, Kamille Dumong|Bjorkling, Fredrik|Madsen, Jacob|Jensen, Peter Buhl|Sehested, Maxwell|Hojgaard, Liselotte|Kjaer, Andreas
PMID: 23226334
Journal: Pharmacogenomics J. 2013 Oct;13(5):410-6.
Title: Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).
Author: Wilson, P M|Yang, D|Azuma, M|Shi, M M|Danenberg, K D|Lebwohl, D|Sherrod, A|Ladner, R D|Zhang, W|Danenberg, P V|Trarbach, T|Folprecht, G|Meinhardt, G|Lenz, H-J
PMID: 22664478
Journal: Gut. 2013 Sep;62(9):1315-26.
Title: MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis.
Author: Hur, Keun|Toiyama, Yuji|Takahashi, Masanobu|Balaguer, Francesc|Nagasaka, Takeshi|Koike, Junichi|Hemmi, Hiromichi|Koi, Minoru|Boland, C Richard|Goel, Ajay
PMID: 22735571
Journal: Int J Colorectal Dis. 2013 Mar;28(3):385-98.
Title: Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy.
Author: Wehler, Thomas C|Hamdi, Swaantje|Maderer, Annett|Graf, Claudine|Gockel, Ines|Schmidtmann, Irene|Hainz, Michael|Berger, Martin R|Theobald, Matthias|Galle, Peter R|Moehler, Markus|Schimanski, Carl C
PMID: 22983756
Journal: Cancer Res. 2013 Jan 15;73(2):539-49.
Title: VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer.
Author: Terme, Magali|Pernot, Simon|Marcheteau, Elie|Sandoval, Federico|Benhamouda, Nadine|Colussi, Orianne|Dubreuil, Olivier|Carpentier, Antoine F|Tartour, Eric|Taieb, Julien
PMID: 23108136
Journal: Oncol Rep. 2013 Mar;29(3):951-9.
Title: Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer.
Author: Matsushita, Norimasa|Aruga, Atsushi|Inoue, Yuji|Kotera, Yoshihito|Takeda, Kazuyoshi|Yamamoto, Masakazu
PMID: 23314271
Journal: J Nucl Med. 2013 Feb;54(2):252-8.
Title: Metformin--an adjunct antineoplastic therapy--divergently modulates tumor metabolism and proliferation, interfering with early response prediction by 18F-FDG PET imaging.
Author: Habibollahi, Peiman|van den Berg, Nynke S|Kuruppu, Darshini|Loda, Massimo|Mahmood, Umar
PMID: 23376854
Journal: Histol Histopathol. 2013 May;28(5):647-53.
Title: VEGF-B expression in colorectal carcinomas and its relevance for tumor progression.
Author: Jayasinghe, Caren|Simiantonaki, Nektaria|Kirkpatrick, Charles James
PMID: 23417498
Journal: Cancer Manag Res. 2013 Apr 12;5:49-55.
Title: Critical appraisal of the use of regorafenib in the management of colorectal cancer.
Author: Festino, Lucia|Fabozzi, Alessio|Manzo, Anna|Gambardella, Valentina|Martinelli, Erika|Troiani, Teresa|De Vita, Ferdinando|Orditura, Michele|Ciardiello, Fortunato|Morgillo, Floriana
PMID: 23610528
Journal: BMC Cancer. 2013 May 7;13:229.
Title: Chronic inhibition of tumor cell-derived VEGF enhances the malignant phenotype of colorectal cancer cells.
Author: Yamagishi, Naoko|Teshima-Kondo, Shigetada|Masuda, Kiyoshi|Nishida, Kensei|Kuwano, Yuki|Dang, Duyen T|Dang, Long H|Nikawa, Takeshi|Rokutan, Kazuhito
PMID: 23651517
Journal: Mol Imaging. 2013 Jul-Aug;12(5):277-87.
Title: Impact of anesthetics on 3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) uptake in animal models of cancer and inflammation.
Author: Fuchs, Kerstin|Kukuk, Damaris|Mahling, Moritz|Quintanilla-Martinez, Leticia|Reischl, Gerald|Reutershan, Jorg|Lang, Florian|Rocken, Martin|Pichler, Bernd J|Kneilling, Manfred
PMID: 23759369
Journal: J Biomed Sci. 2013 Jun 21;20:39.
Title: Flt-1 in colorectal cancer cells is required for the tumor invasive effect of placental growth factor through a p38-MMP9 pathway.
Author: Wei, Shu-Chen|Tsao, Po-Nien|Weng, Meng-Tzu|Cao, Zhifang|Wong, Jau-Min
PMID: 23799978
Journal: Mol Imaging Biol. 2013 Dec;15(6):786-7.
Title: Response to the letter to the editor regarding the manuscript entitled "positron emission tomography with [(18)F]-3'-deoxy-3'fluorothymidine (FLT) as a predictor of outcome in patients with locally advanced resectable rectal cancer: a pilot study".
Author: Dehdashti, Farrokh|Grigsby, Perry W|Siegel, Barry A
PMID: 23813333
Journal: Mol Cancer Ther. 2013 Nov;12(11):2483-93.
Title: The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells.
Author: Sreevalsan, Sandeep|Safe, Stephen
PMID: 24030632
Journal: Biomed Res Int. 2013;2013:545983.
Title: Tyrosine phosphorylation modulates the vascular responses of mesenteric arteries from human colorectal tumors.
Author: Ferrero, Eduardo|Mauricio, Maria Dolores|Granado, Miriam|Garcia-Villar, Oscar|Aldasoro, Martin|Vila, Jose Maria|Hidalgo, Manuel|Ferrero, Jorge Luis|Fernandez, Nuria|Monge, Luis|Garcia-Villalon, Angel Luis
PMID: 24324963
Journal: PLoS One. 2013 Dec 10;8(12):e81763.
Title: The enhanced in vivo activity of the combination of a MEK and a PI3K inhibitor correlates with [18F]-FLT PET in human colorectal cancer xenograft tumour-bearing mice.
Author: Haagensen, Emma J|Thomas, Huw D|Wilson, Ian|Harnor, Suzannah J|Payne, Sara L|Rennison, Tommy|Smith, Kate M|Maxwell, Ross J|Newell, David R
PMID: 24339963
Journal: Gan To Kagaku Ryoho. 2013 Nov;40(12):1584-6.
Title: [Treatment outcome of peptide vaccination for advanced colorectal cancer].
Author: Sugiura, Fumiaki|Inoue, Keisuke|Kogita, Akihiro|Yoshioka, Yasumasa|Hida, Jinichi|Okuno, Kiyotaka|Sukegawa, Yasushi
PMID: 24393856
Journal: Hepatogastroenterology. 2013 Nov-Dec;60(128):1950-4.
Title: Antitumor effect of FP3 on a patient-derived tumor tissue xenograft model of rectal carcinoma.
Author: Bi, Tienan|Bi, Tienan|Lan, Huanrong|Hu, Xinxia|Zhu, Min|Xu, Zhenzhen|Hu, Jinxi|Teng, Lisong|Jin, Ketao
PMID: 24719933
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E140-50.
Title: VEGFA, FLT1, KDR and colorectal cancer: assessment of disease risk, tumor molecular phenotype, and survival.
Author: Slattery, Martha L|Lundgreen, Abbie|Wolff, Roger K
PMID: 23794399
Journal: Endocr Relat Cancer. 2013 Dec 20;21(1):73-84.
Title: GDNF increases cell motility in human colon cancer through VEGF-VEGFR1 interaction.
Author: Huang, Ssu-Ming|Chen, Tzu-Sheng|Chiu, Chien-Ming|Chang, Leang-Kai|Liao, Kuan-Fu|Tan, Hsiao-Ming|Yeh, Wei-Lan|Chang, Gary Ro-Lin|Wang, Min-Ying|Lu, Dah-Yuu
PMID: 24165321
Journal: Int J Mol Med. 2014 May;33(5):1261-7.
Title: Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer.
Author: Kim, Se-Lim|Lee, Soo-Teik|Trang, Kieu Thi Thu|Kim, Seong Hun|Kim, In Hee|Lee, Seung Ok|Kim, Dae Ghon|Kim, Sang-Wook
PMID: 24573421
Journal: J Transl Med. 2014 Mar 10;12:63.
Title: A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Author: Hazama, Shoichi|Nakamura, Yusuke|Takenouchi, Hiroko|Suzuki, Nobuaki|Tsunedomi, Ryouichi|Inoue, Yuka|Tokuhisa, Yoshihiro|Iizuka, Norio|Yoshino, Shigefumi|Takeda, Kazuyoshi|Shinozaki, Hirokazu|Kamiya, Akira|Furukawa, Hiroyuki|Oka, Masaaki
PMID: 24612787
Journal: BMC Genomics. 2014 Mar 13;15:190.
Title: Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author: Castle, John C|Loewer, Martin|Boegel, Sebastian|de Graaf, Jos|Bender, Christian|Tadmor, Arbel D|Boisguerin, Valesca|Bukur, Thomas|Sorn, Patrick|Paret, Claudia|Diken, Mustafa|Kreiter, Sebastian|Tureci, Ozlem|Sahin, Ugur
PMID: 24621249
Journal: BMC Cancer. 2014 Mar 13;14:178.
Title: Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings.
Author: Bieche, Ivan|Vacher, Sophie|Vallerand, David|Richon, Sophie|Hatem, Rana|De Plater, Ludmilla|Dahmani, Ahmed|Nemati, Fariba|Angevin, Eric|Marangoni, Elisabetta|Roman-Roman, Sergio|Decaudin, Didier|Dangles-Marie, Virginie
PMID: 24625025
Journal: Biochem Cell Biol. 2014 Jun;92(3):206-18.
Title: Targeting angiogenic pathway for chemoprevention of experimental colon cancer using C-phycocyanin as cyclooxygenase-2 inhibitor.
Author: Saini, Manpreet Kaur|Sanyal, Sankar Nath
PMID: 24861078
Journal: Tumour Biol. 2014 Sep;35(9):9045-51.
Title: Prognostic significance of VEGFR1/Flt-1 immunoexpression in colorectal carcinoma.
Author: Al-Maghrabi, Jaudah|Gomaa, Wafaey|Buhmeida, Abdelbaset|Qari, Yousif|Al-Qahtani, Mohammad|Al-Ahwal, Mahmoud
PMID: 24908415
Journal: Gastroenterol Res Pract. 2014;2014:526178.
Title: Targeting angiogenesis and tumor microenvironment in metastatic colorectal cancer: role of aflibercept.
Author: Giordano, Guido|Febbraro, Antonio|Venditti, Michele|Campidoglio, Serena|Olivieri, Nunzio|Raieta, Katia|Parcesepe, Pietro|Imbriani, Giusy Carmen|Remo, Andrea|Pancione, Massimo
PMID: 25136356
Journal: Oncology. 2014;87(5):280-92.
Title: Single-nucleotide polymorphisms in the vascular endothelial growth factor pathway and outcomes of patients treated with first-line cytotoxic chemotherapy combined with bevacizumab for advanced colorectal cancer.
Author: Sohn, Byeong Seok|Park, Seong Joon|Kim, Jeong Eun|Kim, Kyu-Pyo|Hong, Yong Sang|Suh, Cheolwon|Kim, Yong Sung|Kim, Seon Young|Im, Seock-Ah|Kim, Sun Young|Kim, Jee Hyun|Ahn, Joong Bae|Park, Young Suk|Kim, Tae Won
PMID: 25139485
Journal: Gan To Kagaku Ryoho. 2014 Oct;41(10):1276-9.
Title: [Clinical trial of a seven-peptide vaccine and tegafur-uracil/leucovorin as combination therapy for advanced colorectal cancer].
Author: Inoue, Keisuke|Sugiura, Fumiaki|Kogita, Akihiro|Yoshioka, Yasumasa|Sukegawa, Yasushi|Hida, Jinichi|Okuno, Kiyotaka
PMID: 25335716
Journal: Surg Today. 2015 Feb;45(2):215-20.
Title: Soluble VEGFR1 concentration in the serum of patients with colorectal cancer.
Author: Abbasi, Oranus|Mashayekhi, Farhad|Mirzajani, Ebrahim|Fakhriyeh Asl, Saba|Mahmoudi, Touraj|Saeedi Saedi, Hamid
PMID: 24676933
Journal: Ann Nucl Med. 2015 Apr;29(3):284-94.
Title: Assessment of response to neoadjuvant radiochemotherapy with F-18 FLT and F-18 FDG PET/CT in patients with rectal cancer.
Author: Rendl, Gundula|Rettenbacher, Lukas|Holzmannhofer, Johannes|Datz, Lidwina|Hauser-Kronberger, Cornelia|Fastner, Gerd|Ofner, Dietmar|Sedlmayer, Felix|Pirich, Christian
PMID: 25503812
Journal: Org Biomol Chem. 2015 Apr 14;13(14):4296-309.
Title: 3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity.
Author: Mudududdla, Ramesh|Guru, Santosh K|Wani, Abubakar|Sharma, Sadhana|Joshi, Prashant|Vishwakarma, Ram A|Kumar, Ajay|Bhushan, Shashi|Bharate, Sandip B
PMID: 25758415
Journal: Cancer Chemother Pharmacol. 2015 May;75(5):1005-13.
Title: Positron emission tomography imaging of human colon cancer xenografts in mice with [18F]fluorothymidine after TAS-102 treatment.
Author: Lee, Haeng Jung|Oh, Seung Jun|Lee, Eun Jung|Chung, Jin Hwa|Kim, Yeseulmi|Ryu, Jin-Sook|Kim, Seog Young|Lee, Seung Jin|Moon, Dae Hyuk|Kim, Tae Won
PMID: 25776904
Journal: Oncotarget. 2015 Apr 30;6(12):10563-76.
Title: Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models.
Author: Cicatiello, Valeria|Apicella, Ivana|Tudisco, Laura|Tarallo, Valeria|Formisano, Luigi|Sandomenico, Annamaria|Kim, Younghee|Bastos-Carvalho, Ana|Orlandi, Augusto|Ambati, Jayakrishna|Ruvo, Menotti|Bianco, Roberto|De Falco, Sandro
PMID: 25868854
Journal: Tumour Biol. 2015 Sep;36(10):7399-407.
Title: Efficient inhibition of growth of metastatic cancer cells after resection of primary colorectal cancer by soluble Flt-1.
Author: Zhang, Yong|Li, Ao|Peng, Weizhen|Sun, Jue|Xu, Fangming|Xu, Jianhua
PMID: 25895458
Journal: Ann Nucl Med. 2015 Jul;29(6):535-42.
Title: [(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study.
Author: McKinley, Eliot T|Watchmaker, Jennifer M|Chakravarthy, A Bapsi|Meyerhardt, Jeffrey A|Engelman, Jeffrey A|Walker, Ronald C|Washington, M Kay|Coffey, Robert J|Manning, H Charles
PMID: 25899481
Journal: Onco Targets Ther. 2015 Apr 15;8:835-43.
Title: The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab.
Author: Zhang, Shu-Dong|McCrudden, Cian M|Meng, Chen|Lin, Yao|Kwok, Hang Fai
PMID: 25926745
Journal: Mol Cancer Res. 2015 Sep;13(9):1274-82.
Title: VEGFR-1 Pseudogene Expression and Regulatory Function in Human Colorectal Cancer Cells.
Author: Ye, Xiangcang|Fan, Fan|Bhattacharya, Rajat|Bellister, Seth|Boulbes, Delphine R|Wang, Rui|Xia, Ling|Ivan, Cristina|Zheng, Xiaofeng|Calin, George A|Wang, Jing|Lu, Xiongbin|Ellis, Lee M
PMID: 26041938
Journal: J Natl Cancer Inst. 2015 Jun 13;107(9). pii: djv160.
Title: A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival.
Author: Sharafeldin, Noha|Slattery, Martha L|Liu, Qi|Franco-Villalobos, Conrado|Caan, Bette J|Potter, John D|Yasui, Yutaka
PMID: 26072521
Journal: Oncol Lett. 2015 May;9(5):2414-2418.
Title: Expression and clinical significance of vascular endothelial growth factor and fms-related tyrosine kinase 1 in colorectal cancer.
Author: Wen, Linchun|Wang, Rui|Lu, Xiyan|You, Chuanwen
PMID: 26137082
Journal: BMC Cancer. 2015 Sep 22;15:643.
Title: Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival.
Author: Paiva, Tadeu Ferreira Jr|de Jesus, Victor Hugo Fonseca|Marques, Raul Amorim|da Costa, Alexandre Andre Balieiro Anastacio|de Macedo, Mariana Petaccia|Peresi, Patricia Maria|Damascena, Aline|Rossi, Benedito Mauro|Begnami, Maria Dirlei|de Lima, Vladmir Claud
PMID: 26394830
Journal: J BUON. 2015 Sep-Oct;20(5):1193-200.
Title: Is there a correlation between peripheral blood expression of angiogenic transcriptional factors/receptors and colorectal cancer?
Author: Manzat-Saplacan, Roberta M|Balacescu, Loredana|Gherman, Claudia|Visan, Simona|Chira, Romeo I|Bintintan, Adriana|Nagy, Georgiana|Popovici, Cornelia|Valean, Simona D|Anca, Craiu|Bintintan, Vasile|Scurtu, Razvan|Mircea, Petru A|Berindan-Neagoe, Ioana|Ciulean
PMID: 26537064
Journal: Mol Carcinog. 2016 May;55(5):411-9.
Title: LoVo colon cancer cells resistant to oxaliplatin overexpress c-MET and VEGFR-1 and respond to VEGF with dephosphorylation of c-MET.
Author: Mezquita, Belen|Pineda, Estela|Mezquita, Jovita|Mezquita, Pau|Pau, Montserrat|Codony-Servat, Jordi|Martinez-Balibrea, Eva|Mora, Conchi|Maurel, Joan|Mezquita, Cristobal
PMID: 25647613
Journal: J Cell Physiol. 2016 May;231(5):1097-105.
Title: Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells.
Author: Mirone, Giovanna|Perna, Stefania|Shukla, Arvind|Marfe, Gabriella
PMID: 26419617
Journal: Drug Metab Pers Ther. 2016 Jun 1;31(2):83-90.
Title: Predictive biomarkers candidates for patients with metastatic colorectal cancer treated with bevacizumab-containing regimen.
Author: Gonzalez-Vacarezza, Nicolas|Alonso, Isabel|Arroyo, Gustavo|Martinez, Jorge|De Andres, Fernando|LLerena, Adrian|Estevez-Carrizo, Francisco
PMID: 26974145
Journal: Cancer Res. 2016 May 15;76(10):3014-24.
Title: Intracrine VEGF Signaling Mediates the Activity of Prosurvival Pathways in Human Colorectal Cancer Cells.
Author: Bhattacharya, Rajat|Ye, Xiang-Cang|Wang, Rui|Ling, Xia|McManus, Madonna|Fan, Fan|Boulbes, Delphine|Ellis, Lee M
PMID: 26988990
Journal: Clin Nucl Med. 2016 Jun;41(6):510-1.
Title: Fibrous Dysplasia Presenting as a Cold Spot in 18F-FLT PET/CT Imaging.
Author: Rehak, Zdenek|Bencsikova, Beatrix|Zambo, Iva|Kazda, Tomas
PMID: 27055128
Journal: Sci Rep. 2016 Apr 27;6:25195.
Title: Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients.
Author: Giampieri, Riccardo|Salvatore, Lisa|Del Prete, Michela|Prochilo, Tiziana|D'Anzeo, Marco|Loretelli, Cristian|Loupakis, Fotios|Aprile, Giuseppe|Maccaroni, Elena|Andrikou, Kalliopi|Bianconi, Maristella|Bittoni, Alessandro|Faloppi, Luca|Demurtas, Laura|Montir
PMID: 27117754
Journal: Int J Mol Epidemiol Genet. 2016 Mar 23;7(1):45-57. eCollection 2016.
Title: Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality.
Author: Slattery, Martha L|Pellatt, Daniel F|Wolff, Roger K|Lundgreen, Abbie
PMID: 27186328
Journal: Anticancer Res. 2016 Jun;36(6):2683-96.
Title: Heterogeneity of Vascular Endothelial Growth Factor Receptors 1, 2, 3 in Primary Human Colorectal Carcinoma.
Author: Nasir, Aejaz|Reising, Leslie O'Neill|Nedderman, Drew M|Fulford, Angie D|Uhlik, Mark T|Benjamin, Laura E|Schade, Andrew E|Holzer, Timothy R
PMID: 27272777
Journal: Clin Cancer Res. 2016 Oct 15;22(20):5058-5067.
Title: BATON-CRC: A Phase II Randomized Trial Comparing Tivozanib Plus mFOLFOX6 with Bevacizumab Plus mFOLFOX6 in Stage IV Metastatic Colorectal Cancer.
Author: Benson, Al B 3rd|Kiss, Igor|Bridgewater, John|Eskens, Ferry A L M|Sasse, Carolyn|Vossen, Sandra|Chen, Jihong|Van Sant, Chip|Ball, Howard A|Keating, Anne|Krivoshik, Andrew
PMID: 27401244
Journal: Oncotarget. 2016 Sep 27;7(39):63124-63137.
Title: DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling.
Author: Huang, Shiu-Wen|Lien, Jin-Cherng|Kuo, Sheng-Chu|Huang, Tur-Fu
PMID: 27517319
Journal: Mol Cell Biochem. 2016 Oct;421(1-2):1-18.
Title: Erythropoietin accelerates tumor growth through increase of erythropoietin receptor (EpoR) as well as by the stimulation of angiogenesis in DLD-1 and Ht-29 xenografts.
Author: Tankiewicz-Kwedlo, A|Hermanowicz, J|Surazynski, A|Rozkiewicz, D|Pryczynicz, A|Domaniewski, T|Pawlak, K|Kemona, A|Pawlak, D
PMID: 27543111
Journal: Tumour Biol. 2017 Mar;39(3):1010428317692263.
Title: Colorectal polypoid lesions and expression of vascular endothelial growth factor in a consecutive series of endoscopic and surgical patients.
Author: Ruffolo, Cesare|Toffolatti, Luisa|Canal, Fabio|Kotsafti, Andromachi|Pagura, Giulia|Pozza, Anna|Campo Dell'Orto, Marta|Ferrara, Francesco|Massani, Marco|Dei Tos, Angelo P|Castoro, Carlo|Bassi, Nicolo|Scarpa, Marco
PMID: 28347226
Journal: Mol Clin Oncol. 2017 Feb;6(2):243-248.
Title: VEGF, Flt-1, and microvessel density in primary tumors as predictive factors of colorectal cancer prognosis.
Author: Zygon, Justyna|Szajewski, Mariusz|Kruszewski, Wieslaw Janusz|Rzepko, Robert
PMID: 28357103
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: Br J Cancer. 2017 Sep 5;117(6):848-855.
Title: Intracrine VEGF signalling mediates colorectal cancer cell migration and invasion.
Author: Bhattacharya, Rajat|Fan, Fan|Wang, Rui|Ye, Xiangcang|Xia, Ling|Boulbes, Delphine|Ellis, Lee M
PMID: 28742793
Journal: Eur J Nucl Med Mol Imaging. 2017 Dec;44(13):2158-2168.
Title: A pilot study for texture analysis of (18)F-FDG and (18)F-FLT-PET/CT to predict tumor recurrence of patients with colorectal cancer who received surgery.
Author: Nakajo, Masatoyo|Kajiya, Yoriko|Tani, Atsushi|Jinguji, Megumi|Nakajo, Masayuki|Kitazono, Masaki|Yoshiura, Takashi
PMID: 28770274
Journal: Cancer Res. 2017 Dec 15;77(24):7120-7130.
Title: [(18)F]fluorothymidine PET Informs the Synergistic Efficacy of Capecitabine and Trifluridine/Tipiracil in Colon Cancer.
Author: Kim, Seog-Young|Jung, Jin Hwa|Lee, Haeng Jung|Soh, Hyunsu|Lee, Sang Ju|Oh, Seung Jun|Chae, Sun Young|Lee, Jai Hyuen|Lee, Seung Jin|Hong, Yong Sang|Kim, Tae Won|Moon, Dae Hyuk
PMID: 29055019
Journal: Exp Ther Med. 2017 Nov;14(5):4263-4271.
Title: Vascular endothelial growth receptor 1 acts as a stress-associated protein in the therapeutic response to thalidomide.
Author: Liu, Qin|Yin, Tao|Wang, Guoping|Guo, Fuchun|Ou, Yuhong|Li, Yi|Wang, Yongsheng
PMID: 29075340
Journal: Oncotarget. 2017 Jul 19;8(44):76375-76384.
Title: Flt-1-positive cells are cancer-stem like cells in colorectal carcinoma.
Author: Huang, Ye|Huang, Yinpeng|Liu, Di|Wang, Tianyi|Bai, Guang
PMID: 29100318
Journal: Endosc Ultrasound. 2018 May-Jun;7(3):175-183.
Title: Assessing tumor angiogenesis in colorectal cancer by quantitative contrast-enhanced endoscopic ultrasound and molecular and immunohistochemical analysis.
Author: Cartana, Elena-Tatiana|Gheonea, Dan Ionut|Cherciu, Irina Florina|Streata, Ioana|Uscatu, Constantin-Daniel|Nicoli, Elena-Raluca|Ioana, Mihai|Pirici, Daniel|Georgescu, Claudia-Valentina|Alexandru, Dragos-Ovidiu|Surlin, Valeriu|Gruionu, Gabriel|Saftoiu, Adri
PMID: 28685747
Journal: Pharmacogenomics J. 2018 Jul;18(4):556-564.
Title: Genetic variants in the VEGF pathway as prognostic factors in stages II and III colon cancer.
Author: Riera, Pau|Virgili, Anna C|Salazar, Juliana|Sebio, Ana|Tobena, Maria|Sullivan, Ivana|Paez, David
PMID: 29282362
Journal: Oncol Rep. 2018 May;39(5):2385-2392.
Title: IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides.
Author: Kanekiyo, Shinsuke|Hazama, Shoichi|Takenouchi, Hiroko|Nakajima, Masao|Shindo, Yoshitaro|Matsui, Hiroto|Tokumitsu, Yukio|Tomochika, Shinobu|Tsunedomi, Ryouichi|Tokuhisa, Yoshihiro|Iida, Michihisa|Sakamoto, Kazuhiko|Suzuki, Nobuaki|Takeda, Shigeru|Yamamoto,
PMID: 29498403
Journal: Hepatobiliary Pancreat Dis Int. 2018 Apr;17(2):140-148.
Title: Prediction of tumor biological characteristics in different colorectal cancer liver metastasis animal models using (18)F-FDG and (18)F-FLT.
Author: Xu, Hai-Long|Li, Man|Zhang, Rong-Jun|Jiang, Hui-Jie|Zhang, Ming-Yu|Li, Xin|Wang, Yi-Qiao|Pan, Wen-Bin
PMID: 29571649
Journal: Clin Colorectal Cancer. 2018 Sep;17(3):e471-e488.
Title: Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study.
Author: Hanna, Diana L|Loupakis, Fotios|Yang, Dongyun|Cremolini, Chiara|Schirripa, Marta|Li, Meng|Matsusaka, Satoshi|Berger, Martin D|Miyamoto, Yuji|Zhang, Wu|Ning, Yan|Antoniotti, Carlotta|Salvatore, Lisa|Moran, Miriana|Zeger, Gary|Astrow, Stephanie H|Falcone, A
PMID: 29636300
Journal: Theranostics. 2018 Mar 7;8(8):2094-2106.
Title: Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy.
Author: Feng, Junnan|Zhao, Chuanke|Wang, Lixin|Qu, Like|Zhu, Hua|Yang, Zhi|An, Guo|Tian, Huifang|Shou, Chengchao
PMID: 29721065
Journal: Cancer Control. 2018 Jan-Dec;25(1):1073274818789361.
Title: Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers.
Author: Suyama, Koichi|Iwase, Hirotaka
PMID: 30032643
Journal: J Control Release. 2018 Sep 11;288:161-172.
Title: Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy.
Author: Weyergang, Anette|Fremstedal, Ane S|Skarpen, Ellen|Peng, Qian|Mohamedali, Khalid A|Eng, Marius S|Cheung, Lawrence H|Rosenblum, Michael G|Waltenberger, Johannes|Berg, Kristian
PMID: 30217739
Journal: J Vasc Interv Radiol. 2018 Oct 15. pii: S1051-0443(18)31417-9.
Title: Irinotecan-Eluting 75-150-mum Embolics Lobar Chemoembolization in Patients with Colorectal Cancer Liver Metastases: A Prospective Single-Center Phase I Study.
Author: Fereydooni, Arash|Letzen, Brian|Ghani, Mansur A|Miszczuk, Milena A|Huber, Steffen|Chapiro, Julius|Schlachter, Todd|Geschwind, Jean-Francois|Georgiades, Christos
PMID: 30337148