Primary Site >> Liver Cancer

Gene >> FGFR2

Journal: Hepatology. 1996 Jul;24(1):198-205.
Title: Expressions of basic fibroblast growth factor and its receptors and their relationship to proliferation of human hepatocellular carcinoma cell lines.
Author: Ogasawara, S|Yano, H|Iemura, A|Hisaka, T|Kojiro, M
PMID: 8707262
Journal: World J Gastroenterol. 2013 Apr 28;19(16):2481-91.
Title: Emodin regulating excision repair cross-complementation group 1 through fibroblast growth factor receptor 2 signaling.
Author: Chen, Gang|Qiu, Hong|Ke, Shan-Dong|Hu, Shao-Ming|Yu, Shi-Ying|Zou, Sheng-Quan
PMID: 23674849
Journal: Biomed Rep. 2013 Jul;1(4):604-608.
Title: The fibroblast growth factor receptor 2-mediated extracellular signal-regulated kinase 1/2 signaling pathway plays is important in regulating excision repair cross-complementary gene 1 expression in hepatocellular carcinoma.
Author: Chen, Gang|Qiu, Hong|Ke, Shandong|Hu, Shaoming|Yu, Shiying|Zou, Shengquan
PMID: 24648994
Journal: Hepatology. 2014 Apr;59(4):1427-34.
Title: Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.
Author: Arai, Yasuhito|Totoki, Yasushi|Hosoda, Fumie|Shirota, Tomoki|Hama, Natsuko|Nakamura, Hiromi|Ojima, Hidenori|Furuta, Koh|Shimada, Kazuaki|Okusaka, Takuji|Kosuge, Tomoo|Shibata, Tatsuhiro
PMID: 24122810
Journal: Oncogene. 2014 Sep 25;33(39):4786-94.
Title: Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing.
Author: Lin, K-T|Shann, Y-J|Chau, G-Y|Hsu, C-N|Huang, C-Y F
PMID: 24141781
Journal: Oncologist. 2014 Mar;19(3):235-42.
Title: New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.
Author: Ross, Jeffrey S|Wang, Kai|Gay, Laurie|Al-Rohil, Rami|Rand, Janne V|Jones, David M|Lee, Hwa J|Sheehan, Christine E|Otto, Geoff A|Palmer, Gary|Yelensky, Roman|Lipson, Doron|Morosini, Deborah|Hawryluk, Matthew|Catenacci, Daniel V T|Miller, Vincent A|Churi, C
PMID: 24563076
Journal: Int J Cancer. 2014 Dec 15;135(12):2972-83.
Title: A preclinical evaluation of a novel multikinase inhibitor, SKLB-329, as a therapeutic agent against hepatocellular carcinoma.
Author: Zhong, Lei|Fu, Xiao-Yu|Zou, Chan|Yang, Ling-Ling|Zhou, Shu|Yang, Jiao|Tang, Yun|Cheng, Chuan|Li, Lin-Li|Xiang, Rong|Chen, Li-Juan|Chen, Yu-Zong|Wei, Yu-Quan|Yang, Sheng-Yong
PMID: 24789676
Journal: Tumour Biol. 2014 Nov;35(11):11005-11.
Title: Inhibition of fibroblast growth factor receptor signaling impairs metastasis of hepatocellular carcinoma.
Author: Wang, Jiajun|Su, Hongying|Han, Xiangjun|Xu, Ke
PMID: 25091573
Journal: Mol Cancer Ther. 2015 Nov;14(11):2613-22.
Title: Targeting FGFR Pathway in Human Hepatocellular Carcinoma: Expressing pFGFR and pMET for Antitumor Activity.
Author: Jo, Jae-Cheol|Choi, Eun Kyoung|Shin, Jae-Sik|Moon, Jai-Hee|Hong, Seung-Woo|Lee, Ha-Reum|Kim, Seung-Mi|Jung, Soo-A|Lee, Dae-Hee|Jung, Seang Hwan|Lee, Sun-Hye|Kim, Jeong Eun|Kim, Kyu-pyo|Hong, Yong Sang|Suh, Young-Ah|Jang, Se Jin|Choi, Eun Kyung|Lee, Jung S
PMID: 26351320
Journal: Clin Mol Hepatol. 2015 Mar;21(1):60-70.
Title: Fibroblast growth factor receptor isotype expression and its association with overall survival in patients with hepatocellular carcinoma.
Author: Lee, Hyo Jeong|Kang, Hyo Jeong|Kim, Kang Mo|Yu, Eun Sil|Kim, Ki Hun|Kim, Seung-Mi|Kim, Tae Won|Shim, Ju Hyun|Lim, Young-Suk|Lee, Han Chu|Chung, Young-Hwa|Lee, Yung Sang
PMID: 25834803
Journal: Nat Commun. 2015 Jan 22;6:6087.
Title: Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.
Author: Sia, Daniela|Losic, Bojan|Moeini, Agrin|Cabellos, Laia|Hao, Ke|Revill, Kate|Bonal, Dennis|Miltiadous, Oriana|Zhang, Zhongyang|Hoshida, Yujin|Cornella, Helena|Castillo-Martin, Mireia|Pinyol, Roser|Kasai, Yumi|Roayaie, Sasan|Thung, Swan N|Fuster, Josep|Schw
PMID: 25608663
Journal: Int J Cancer. 2016 Mar 15;138(6):1494-505.
Title: Molecular subclasses of hepatocellular carcinoma predict sensitivity to fibroblast growth factor receptor inhibition.
Author: Schmidt, Benjamin|Wei, Lan|DePeralta, Danielle K|Hoshida, Yujin|Tan, Poh Seng|Sun, Xiaochen|Sventek, Janelle P|Lanuti, Michael|Tanabe, Kenneth K|Fuchs, Bryan C
PMID: 26481559
Journal: Oncotarget. 2016 Jul 19;7(29):46750-46767.
Title: The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets.
Author: Chong, Dawn Q|Zhu, Andrew X
PMID: 27102149
Journal: Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title: Genomic characterization of liver metastases from colorectal cancer patients.
Author: Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant
PMID: 27662660
Journal: J Mol Cell Biol. 2017 Jun 1;9(3):243-255.
Title: SNORD126 promotes HCC and CRC cell growth by activating the PI3K-AKT pathway through FGFR2.
Author: Fang, Xianlong|Yang, Dongmei|Luo, Hongping|Wu, Shuai|Dong, Wenjie|Xiao, Jing|Yuan, Sujing|Ni, Aimin|Zhang, Kang-Jian|Liu, Xin-Yuan|Chu, Liang
PMID: 27913571
Journal: J Cancer. 2017 Feb 25;8(5):730-736.
Title: An investigation of the role of gene copy number variations in sorafenib sensitivity in metastatic hepatocellular carcinoma patients.
Author: Lee, Ji Yun|Hong, Mineui|Lee, Jeeyun|Lee, Sujin|Kim, Kyoung-Mee|Park, Cheolkeun|Lim, Ho Yeong
PMID: 28382134
Journal: Tumour Biol. 2017 Jun;39(6):1010428317707424.
Title: Prognostic role of fibroblast growth factor receptor 2 in human solid tumors: A systematic review and meta-analysis.
Author: Liu, Gang|Xiong, Disheng|Xiao, Rui|Huang, Zhengjie
PMID: 28618942
Journal: Future Oncol. 2018 Mar;14(6):553-566.
Title: Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma.
Author: DeLeon, Thomas T|Ahn, Daniel H|Bogenberger, James M|Anastasiadis, Panos Z|Arora, Mansi|Ramanathan, Ramesh K|Aqel, Bashar A|Vasmatzis, George|Truty, Mark J|Oklu, Rahmi|Bekaii-Saab, Tanios S|Borad, Mitesh J
PMID: 29460642
Journal: Hum Pathol. 2018 Jun;76:100-109.
Title: Low-level clonal FGFR2 amplification defines a unique molecular subtype of intrahepatic cholangiocarcinoma in a Chinese population.
Author: Pu, Xiao-Hong|Ye, Qing|Yang, Jun|Wu, Hong-Yan|Ding, Xi-Wei|Shi, Jiong|Mao, Liang|Fan, Xiang-Shan|Chen, Jun|Qiu, Yu-Dong|Huang, Qin
PMID: 29514108
Journal: BMC Cancer. 2018 Jun 7;18(1):640.
Title: Deep sequencing of human papillomavirus positive loco-regionally advanced oropharyngeal squamous cell carcinomas reveals novel mutational signature.
Author: Gronhoj, Christian|Jensen, David H|Agander, Tina|Kiss, Katalin|Hogdall, Estrid|Specht, Lena|Bagger, Frederik Otzen|Nielsen, Finn Cilius|von Buchwald, Christian
PMID: 29879932
Journal: Oncotarget. 2018 Aug 14;9(63):32204-32218.
Title: FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis.
Author: Fromme, Julia Elisabeth|Schmitz, Katja|Wachter, Astrid|Grzelinski, Marius|Zielinski, Dirk|Koppel, Christina|Conradi, Lena-Christin|Homayounfar, Kia|Hugo, Tabea|Hugo, Sara|Lukat, Laura|Ruschoff, Josef|Strobel, Philipp|Ghadimi, Michael|Beissbarth, Tim|Reute
PMID: 30181810