Literatures

Primary Site >> Stomach Cancer

Gene >> FGFR2

1.
Journal:	Proc Natl Acad Sci U S A. 1990 Aug;87(15):5983-7.
Title:	K-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genes.
Author:	Hattori, Y\|Odagiri, H\|Nakatani, H\|Miyagawa, K\|Naito, K\|Sakamoto, H\|Katoh, O\|Yoshida, T\|Sugimura, T\|Terada, M
PMID:	2377625

2.
Journal:	Cancer Genet Cytogenet. 1993 Feb;65(2):111-4.
Title:	DNA amplification in human gastric carcinomas.
Author:	Mor, O\|Ranzani, G N\|Ravia, Y\|Rotman, G\|Gutman, M\|Manor, A\|Amadori, D\|Houldsworth, J\|Hollstein, M\|Schwab, M\|Shiloh, Y
PMID:	8453595

3.
Journal:	Biochem Biophys Res Commun. 1994 Aug 15;202(3):1387-94.
Title:	A soluble form of K-sam/FGFR2 protein in the culture medium of human gastric cancer cells.
Author:	Kishi, T\|Yoshida, T\|Terada, M
PMID:	8060318

4.
Journal:	Cancer Res. 1994 Jun 15;54(12):3237-41.
Title:	Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity.
Author:	Itoh, H\|Hattori, Y\|Sakamoto, H\|Ishii, H\|Kishi, T\|Sasaki, H\|Yoshida, T\|Koono, M\|Sugimura, T\|Terada, M
PMID:	8205545

5.
Journal:	Cancer Res. 1994 Jan 15;54(2):518-22.
Title:	Preferential expression of the third immunoglobulin-like domain of K-sam product provides keratinocyte growth factor-dependent growth in carcinoma cell lines.
Author:	Ishii, H\|Hattori, Y\|Itoh, H\|Kishi, T\|Yoshida, T\|Sakamoto, H\|Oh, H\|Yoshida, S\|Sugimura, T\|Terada, M
PMID:	8275490

6.
Journal:	Mol Cell Biol. 1995 Jul;15(7):3664-71.
Title:	A truncated K-sam product lacking the distal carboxyl-terminal portion provides a reduced level of autophosphorylation and greater resistance against induction of differentiation.
Author:	Ishii, H\|Yoshida, T\|Oh, H\|Yoshida, S\|Terada, M
PMID:	7791773

7.
Journal:	Clin Cancer Res. 1996 Aug;2(8):1373-81.
Title:	Immunohistochemical detection of K-sam protein in stomach cancer.
Author:	Hattori, Y\|Itoh, H\|Uchino, S\|Hosokawa, K\|Ochiai, A\|Ino, Y\|Ishii, H\|Sakamoto, H\|Yamaguchi, N\|Yanagihara, K\|Hirohashi, S\|Sugimura, T\|Terada, M
PMID:	9816310

8.
Journal:	Cancer Res. 1999 Dec 15;59(24):6080-6.
Title:	Deletion of the carboxyl-terminal exons of K-sam/FGFR2 by short homology-mediated recombination, generating preferential expression of specific messenger RNAs.
Author:	Ueda, T\|Sasaki, H\|Kuwahara, Y\|Nezu, M\|Shibuya, T\|Sakamoto, H\|Ishii, H\|Yanagihara, K\|Mafune, K\|Makuuchi, M\|Terada, M
PMID:	10626794

9.
Journal:	J Cancer Res Clin Oncol. 2000 Sep;126(9):519-28.
Title:	Up-regulation and co-expression of fibroblast growth factor receptors in human gastric cancer.
Author:	Shin, E Y\|Lee, B H\|Yang, J H\|Shin, K S\|Lee, G K\|Yun, H Y\|Song, Y J\|Park, S C\|Kim, E G
PMID:	11003564

10.
Journal:	Cancer Res. 2001 May 1;61(9):3541-3.
Title:	Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.
Author:	Jang, J H\|Shin, K H\|Park, J G
PMID:	11325814

11.
Journal:	Int J Oncol. 2003 May;22(5):1155-9.
Title:	FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	12684685

12.
Journal:	Int J Mol Med. 2003 May;11(5):579-83.
Title:	Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	12684693

13.
Journal:	Int J Oncol. 2003 Jun;22(6):1369-74.
Title:	MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	12739007

14.
Journal:	J Pathol. 2003 Nov;201(3):439-50.
Title:	Alterations of chromosomal copy number during progression of diffuse-type gastric carcinomas: metaphase- and array-based comparative genomic hybridization analyses of multiple samples from individual tumours.
Author:	Peng, Dun-Fa\|Sugihara, Hiroyuki\|Mukaisho, Ken-ichi\|Tsubosa, Yasuhiro\|Hattori, Takanori
PMID:	14595756

15.
Journal:	FEBS Lett. 2004 Dec 3;578(1-2):21-5.
Title:	FIGC, a novel FGF-induced ubiquitin-protein ligase in gastric cancers.
Author:	Jang, Jun-Hyeog
PMID:	15581609

16.
Journal:	Int J Oncol. 2005 Apr;26(4):1129-33.
Title:	Comparative genomics on Wnt8a and Wnt8b genes.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	15754011

17.
Journal:	Cancer Genet Cytogenet. 2005 Apr 15;158(2):142-7.
Title:	Allelic loss at 10q26 in osteosarcoma in the region of the BUB3 and FGFR2 genes.
Author:	Mendoza, Susana\|David, Heldi\|Gaylord, Grace M\|Miller, Carl W
PMID:	15796961

18.
Journal:	Int J Mol Med. 2005 Jul;16(1):181-5.
Title:	Comparative genomics on Shisa orthologs.
Author:	Katoh, Yuriko\|Katoh, Masaru
PMID:	15942696

19.
Journal:	Int J Oncol. 2005 Dec;27(6):1677-83.
Title:	Epithelial-mesenchymal transition in gastric cancer (Review).
Author:	Katoh, Masaru
PMID:	16273224

20.
Journal:	Int J Oncol. 2006 Feb;28(2):307-14.
Title:	Expression of keratinocyte growth factor receptor correlates with expansive growth and early stage of gastric cancer.
Author:	Matsunobu, Tetsuro\|Ishiwata, Toshiyuki\|Yoshino, Masanori\|Watanabe, Masanori\|Kudo, Mitsuhiro\|Matsumoto, Koshi\|Tokunaga, Akira\|Tajiri, Takashi\|Naito, Zenya
PMID:	16391783

21.
Journal:	Int J Oncol. 2006 Jul;29(1):163-8.
Title:	FGF signaling network in the gastrointestinal tract (review).
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	16773196

22.
Journal:	Biochem Biophys Res Commun. 2007 Jun 15;357(4):1011-5. Epub 2007 Apr 18.
Title:	Aberrant hypermethylation of the FGFR2 gene in human gastric cancer cell lines.
Author:	Park, Soonok\|Kim, Ji-Hyun\|Jang, Jun-Hyeog
PMID:	17459342

23.
Journal:	Clin Cancer Res. 2007 May 15;13(10):3051-7.
Title:	AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor.
Author:	Takeda, Masayuki\|Arao, Tokuzo\|Yokote, Hideyuki\|Komatsu, Teruo\|Yanagihara, Kazuyoshi\|Sasaki, Hiroki\|Yamada, Yasuhide\|Tamura, Tomohide\|Fukuoka, Kazuya\|Kimura, Hiroshi\|Saijo, Nagahiro\|Nishio, Kazuto
PMID:	17505008

24.
Journal:	Int J Cancer. 2007 Sep 15;121(6):1265-73.
Title:	Transforming properties of TC-1 in human breast cancer: interaction with FGFR2 and beta-catenin signaling pathways.
Author:	Yang, Zeng-Quan\|Moffa, Allison B\|Haddad, Ramsi\|Streicher, Katie L\|Ethier, Stephen P
PMID:	17520678

25.
Journal:	Differentiation. 2007 Nov;75(9):831-42. Epub 2007 Aug 14.
Title:	Aberrant fibroblast growth factor receptor signaling in bladder and other cancers.
Author:	Chaffer, Christine L\|Dopheide, Bonnie\|Savagner, Pierre\|Thompson, Erik W\|Williams, Elizabeth D
PMID:	17697126

26.
Journal:	Cancer Res. 2008 Apr 1;68(7):2340-8.
Title:	FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.
Author:	Kunii, Kaiko\|Davis, Lenora\|Gorenstein, Julie\|Hatch, Harold\|Yashiro, Masakazu\|Di Bacco, Alessandra\|Elbi, Cem\|Lutterbach, Bart
PMID:	18381441

27.
Journal:	Int J Oncol. 2008 Aug;33(2):233-7.
Title:	Cancer genomics and genetics of FGFR2 (Review).
Author:	Katoh, Masaru
PMID:	18636142

28.
Journal:	Int J Mol Med. 2009 Mar;23(3):307-11.
Title:	FGFR2-related pathogenesis and FGFR2-targeted therapeutics (Review).
Author:	Katoh, Yuriko\|Katoh, Masaru
PMID:	19212647

29.
Journal:	J Invest Dermatol. 2009 Aug;129(8):1861-7.
Title:	FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies.
Author:	Katoh, Masaru
PMID:	19387476

30.
Journal:	Int J Cancer. 2010 Feb 15;126(4):1004-16.
Title:	Synergistic antitumor effects of FGFR2 inhibitor with 5-fluorouracil on scirrhous gastric carcinoma.
Author:	Yashiro, Masakazu\|Shinto, Osamu\|Nakamura, Kazunori\|Tendo, Masashige\|Matsuoka, Tasuku\|Matsuzaki, Taro\|Kaizaki, Ryoji\|Miwa, Atsushi\|Hirakawa, Kosei
PMID:	19621385

31.
Journal:	Cancer Res. 2010 Feb 15;70(4):1524-33.
Title:	MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.
Author:	Pan, Bo-Sheng\|Chan, Grace K Y\|Chenard, Melissa\|Chi, An\|Davis, Lenora J\|Deshmukh, Sujal V\|Gibbs, Jackson B\|Gil, Susana\|Hang, Gaozhen\|Hatch, Harold\|Jewell, James P\|Kariv, Ilona\|Katz, Jason D\|Kunii, Kaiko\|Lu, Wei\|Lutterbach, Bart A\|Paweletz, Cloud P\|Qu, Xian
PMID:	20145145

32.
Journal:	Biochem Biophys Res Commun. 2010 Apr 16;394(4):1042-6.
Title:	Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion.
Author:	Asaoka, Yoshinari\|Tada, Motohisa\|Ikenoue, Tsuneo\|Seto, Motoko\|Imai, Mitsuho\|Miyabayashi, Koji\|Yamamoto, Keisuke\|Yamamoto, Shinzo\|Kudo, Yotaro\|Mohri, Dai\|Isomura, Yoshihiro\|Ijichi, Hideaki\|Tateishi, Keisuke\|Kanai, Fumihiko\|Ogawa, Seishi\|Omata, Masao\|Koike,
PMID:	20331976

33.
Journal:	Clin Cancer Res. 2010 Dec 1;16(23):5750-8.
Title:	Monoclonal antibodies to fibroblast growth factor receptor 2 effectively inhibit growth of gastric tumor xenografts.
Author:	Zhao, Wei-meng\|Wang, Lihong\|Park, Hangil\|Chhim, Sophea\|Tanphanich, Melanie\|Yashiro, Masakazu\|Kim, K Jin
PMID:	20670946

34.
Journal:	Cancer Res. 2010 Oct 1;70(19):7630-9.
Title:	GP369, an FGFR2-IIIb-specific antibody, exhibits potent antitumor activity against human cancers driven by activated FGFR2 signaling.
Author:	Bai, Ailin\|Meetze, Kristan\|Vo, Nhi Y\|Kollipara, Sriram\|Mazsa, Elizabeth K\|Winston, William M\|Weiler, Solly\|Poling, Laura L\|Chen, Ting\|Ismail, Nesreen S\|Jiang, Jinwei\|Lerner, Lorena\|Gyuris, Jeno\|Weng, Zhigang
PMID:	20709759

35.
Journal:	Expert Rev Anticancer Ther. 2010 Sep;10(9):1375-9.
Title:	Genetic alterations of FGF receptors: an emerging field in clinical cancer diagnostics and therapeutics.
Author:	Katoh, Masaru
PMID:	20836672

36.
Journal:	Expert Opin Investig Drugs. 2011 May;20(5):595-604.
Title:	New targeted therapies for gastric cancer.
Author:	Asaoka, Yoshinari\|Ikenoue, Tsuneo\|Koike, Kazuhiko
PMID:	21406037

37.
Journal:	Cancer Lett. 2011 Aug 1;307(1):47-52.
Title:	A FGFR2 inhibitor, Ki23057, enhances the chemosensitivity of drug-resistant gastric cancer cells.
Author:	Qiu, Hong\|Yashiro, Masakazu\|Zhang, Xiaotian\|Miwa, Atsushi\|Hirakawa, Kosei
PMID:	21482024

38.
Journal:	Pharmacogenomics J. 2012 Apr;12(2):119-27.
Title:	Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy.
Author:	Kim, H K\|Choi, I J\|Kim, C G\|Kim, H S\|Oshima, A\|Yamada, Y\|Arao, T\|Nishio, K\|Michalowski, A\|Green, J E
PMID:	21173787

39.
Journal:	Invest New Drugs. 2012 Aug;30(4):1352-60.
Title:	Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks.
Author:	Kataoka, Yu\|Mukohara, Toru\|Tomioka, Hideo\|Funakoshi, Yohei\|Kiyota, Naomi\|Fujiwara, Yutaka\|Yashiro, Masakazu\|Hirakawa, Kosei\|Hirai, Midori\|Minami, Hironobu
PMID:	21655918

40.
Journal:	Cancer Sci. 2012 Feb;103(2):221-7.
Title:	Integrated analysis of whole genome exon array and array-comparative genomic hybridization in gastric and colorectal cancer cells.
Author:	Furuta, Kazuyuki\|Arao, Tokuzo\|Sakai, Kazuko\|Kimura, Hideharu\|Nagai, Tomoyuki\|Tamura, Daisuke\|Aomatsu, Keiichi\|Kudo, Kanae\|Kaneda, Hiroyasu\|Fujita, Yoshihiko\|Matsumoto, Kazuko\|Yamada, Yasuhide\|Yanagihara, Kazuyoshi\|Sekijima, Masaru\|Nishio, Kazuto
PMID:	22034905

41.
Journal:	Br J Cancer. 2012 Feb 14;106(4):727-32.
Title:	FGFR2 gene amplification and clinicopathological features in gastric cancer.
Author:	Matsumoto, K\|Arao, T\|Hamaguchi, T\|Shimada, Y\|Kato, K\|Oda, I\|Taniguchi, H\|Koizumi, F\|Yanagihara, K\|Sasaki, H\|Nishio, K\|Yamada, Y
PMID:	22240789

42.
Journal:	Gut. 2012 May;61(5):673-84.
Title:	A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets.
Author:	Deng, Niantao\|Goh, Liang Kee\|Wang, Hannah\|Das, Kakoli\|Tao, Jiong\|Tan, Iain Beehuat\|Zhang, Shenli\|Lee, Minghui\|Wu, Jeanie\|Lim, Kiat Hon\|Lei, Zhengdeng\|Goh, Glenn\|Lim, Qing-Yan\|Tan, Angie Lay-Keng\|Sin Poh, Dianne Yu\|Riahi, Sudep\|Bell, Sandra\|Shi, Michael M\|
PMID:	22315472

43.
Journal:	Hum Pathol. 2012 Oct;43(10):1559-66.
Title:	Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma.
Author:	Jung, Eun-Jung\|Jung, Eun-Ji\|Min, Sun Young\|Kim, Min A\|Kim, Woo Ho
PMID:	22440694

44.
Journal:	J Proteome Res. 2012 Jun 1;11(6):3405-13.
Title:	Multidimensional identification of tissue biomarkers of gastric cancer.
Author:	Guo, Tiannan\|Fan, Lingling\|Ng, Wai Har\|Zhu, Yi\|Ho, Mengfatt\|Wan, Wei Keat\|Lim, Kiat Hon\|Ong, Whee Sze\|Lee, Sze Sing\|Huang, Shiang\|Kon, Oi Lian\|Sze, Siu Kwan
PMID:	22533479

45.
Journal:	Cancer Res. 2012 Sep 1;72(17):4383-93.
Title:	Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
Author:	Dulak, Austin M\|Schumacher, Steven E\|van Lieshout, Jasper\|Imamura, Yu\|Fox, Cameron\|Shim, Byoungyong\|Ramos, Alex H\|Saksena, Gordon\|Baca, Sylvan C\|Baselga, Jose\|Tabernero, Josep\|Barretina, Jordi\|Enzinger, Peter C\|Corso, Giovanni\|Roviello, Franco\|Lin, Lin\|Ba
PMID:	22751462

46.
Journal:	Nihon Rinsho. 2012 Oct;70(10):1812-6.
Title:	[Mechanisms responsible for the progression of scirrhous gastric cancer].
Author:	Yashiro, Masakazu\|Ohira, Masaichi\|Muguruma, Kazuya\|Shinto, Osamu\|Hirakawa, Kosei
PMID:	23198567

47.
Journal:	Clin Cancer Res. 2013 May 1;19(9):2572-83.
Title:	FGFR2 gene amplification in gastric cancer predicts sensitivity to the selective FGFR inhibitor AZD4547.
Author:	Xie, Liang\|Su, Xinying\|Zhang, Lin\|Yin, Xiaolu\|Tang, Lili\|Zhang, Xiuhua\|Xu, Yanping\|Gao, Zeren\|Liu, Kunji\|Zhou, Minhua\|Gao, Beirong\|Shen, Danping\|Zhang, Lianhai\|Ji, Jiafu\|Gavine, Paul R\|Zhang, Jingchuan\|Kilgour, Elaine\|Zhang, Xiaolin\|Ji, Qunsheng
PMID:	23493349

48.
Journal:	Mol Cancer Ther. 2013 Sep;12(9):1749-62.
Title:	S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Author:	Burbridge, Mike F\|Bossard, Celine J\|Saunier, Carine\|Fejes, Imre\|Bruno, Alain\|Leonce, Stephane\|Ferry, Gilles\|Da Violante, Georges\|Bouzom, Francois\|Cattan, Valerie\|Jacquet-Bescond, Anne\|Comoglio, Paolo M\|Lockhart, Brian P\|Boutin, Jean A\|Cordi, Alex\|Ortuno,
PMID:	23804704

49.
Journal:	Discov Med. 2013 Jun;15(85):333-41.
Title:	Towards the goal of personalized medicine in gastric cancer--time to move beyond HER2 inhibition. Part I: Targeting receptor tyrosine kinase gene amplification.
Author:	Lee, Jeeyun\|Ou, Sai-Hong Ignatius
PMID:	23819947

50.
Journal:	Discov Med. 2013 Aug;16(86):7-14.
Title:	Towards the goal of personalized medicine in gastric cancer--time to move beyond HER2 inhibition. Part II: Targeting gene mutations and gene amplifications and the angiogenesis pathway.
Author:	Lee, Jeeyun\|Ou, Sai-Hong Ignatius
PMID:	23911227

51.
Journal:	Acta Pharm Hung. 2013;83(2):47-56.
Title:	[Developing FGFR inhibitors as potential anti-cancer agents].
Author:	Zsakai, Lilian\|Nemeth, Gabor\|Szantai-Kis, Csaba\|Greff, Zoltan\|Horvath, Zoltan\|Szokol, Balint\|Baska, Ferenc\|Boon, Tin Chuad\|Orfi, Laszlo\|Keri, Gyorgya
PMID:	23926649

52.
Journal:	Expert Rev Gastroenterol Hepatol. 2013 Nov;7(8):759-65.
Title:	Fibroblast growth factor receptor 2: a therapeutic target in gastric cancer.
Author:	Hong, Liu\|Han, Yu\|Liu, Jinqiang\|Brain, Lubi
PMID:	24134151

53.
Journal:	Med Res Rev. 2014 Mar;34(2):280-300.
Title:	FGF receptors: cancer biology and therapeutics.
Author:	Katoh, Masaru\|Nakagama, Hitoshi
PMID:	23696246

54.
Journal:	Hepatology. 2014 Apr;59(4):1427-34.
Title:	Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.
Author:	Arai, Yasuhito\|Totoki, Yasushi\|Hosoda, Fumie\|Shirota, Tomoki\|Hama, Natsuko\|Nakamura, Hiromi\|Ojima, Hidenori\|Furuta, Koh\|Shimada, Kazuaki\|Okusaka, Takuji\|Kosuge, Tomoo\|Shibata, Tatsuhiro
PMID:	24122810

55.
Journal:	Br J Cancer. 2014 Feb 18;110(4):967-75.
Title:	FGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study.
Author:	Su, X\|Zhan, P\|Gavine, P R\|Morgan, S\|Womack, C\|Ni, X\|Shen, D\|Bang, Y-J\|Im, S-A\|Ho Kim, W\|Jung, E-J\|Grabsch, H I\|Kilgour, E
PMID:	24457912

56.
Journal:	Hum Pathol. 2014 Apr;45(4):725-34.
Title:	Intratumoral heterogeneous amplification of ERBB2 and subclonal genetic diversity in gastric cancers revealed by multiple ligation-dependent probe amplification and fluorescence in situ hybridization.
Author:	Tajiri, Ryosuke\|Ooi, Akishi\|Fujimura, Takashi\|Dobashi, Yoh\|Oyama, Takeru\|Nakamura, Ritsuko\|Ikeda, Hiroko
PMID:	24491355

57.
Journal:	Br J Cancer. 2014 Mar 4;110(5):1169-78.
Title:	HER2, MET and FGFR2 oncogenic driver alterations define distinct molecular segments for targeted therapies in gastric carcinoma.
Author:	Liu, Y J\|Shen, D\|Yin, X\|Gavine, P\|Zhang, T\|Su, X\|Zhan, P\|Xu, Y\|Lv, J\|Qian, J\|Liu, C\|Sun, Y\|Qian, Z\|Zhang, J\|Gu, Y\|Ni, X
PMID:	24518603

58.
Journal:	Cancer Sci. 2014 May;105(5):528-36.
Title:	Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors.
Author:	Yamaguchi, Hideki\|Takanashi, Miho\|Yoshida, Nachi\|Ito, Yuumi\|Kamata, Reiko\|Fukami, Kiyoko\|Yanagihara, Kazuyoshi\|Sakai, Ryuichi
PMID:	24612061

59.
Journal:	World J Gastroenterol. 2014 Apr 28;20(16):4536-45.
Title:	Targeting receptor tyrosine kinases in gastric cancer.
Author:	Morishita, Asahiro\|Gong, Jian\|Masaki, Tsutomu
PMID:	24782606

60.
Journal:	Genes Chromosomes Cancer. 2014 Nov;53(11):883-94.
Title:	Whole genome gene copy number profiling of gastric cancer identifies PAK1 and KRAS gene amplification as therapy targets.
Author:	Qian, Ziliang\|Zhu, Guanshan\|Tang, Lili\|Wang, Mei\|Zhang, Lianhai\|Fu, Jiangang\|Huang, Chunlei\|Fan, Shuqiong\|Sun, Yun\|Lv, Jing\|Dong, Hua\|Gao, Beirong\|Su, Xinying\|Yu, Dehua\|Zang, Jie\|Zhang, Xiaolin\|Ji, Jiafu\|Ji, Qunsheng
PMID:	24935174

61.
Journal:	Mol Clin Oncol. 2014 Jul;2(4):509-517.
Title:	Prognostic significance of the co-overexpression of fibroblast growth factor receptors 1, 2 and 4 in gastric cancer.
Author:	Murase, Hideaki\|Inokuchi, Mikito\|Takagi, Yoko\|Kato, Keiji\|Kojima, Kazuyuki\|Sugihara, Kenichi
PMID:	24940486

62.
Journal:	PLoS One. 2014 Jun 26;9(6):e98515.
Title:	FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
Author:	Mathur, Anjili\|Ware, Christopher\|Davis, Lenora\|Gazdar, Adi\|Pan, Bo-Sheng\|Lutterbach, Bart
PMID:	24968263

63.
Journal:	Pathol Int. 2014 Jul;64(7):309-14.
Title:	Overexpression of miR-17 in gastric cancer is correlated with proliferation-associated oncogene amplification.
Author:	Park, Dongmin\|Lee, Seok Cheol\|Park, Jun Won\|Cho, Soo Young\|Kim, Hark Kyun
PMID:	25047501

64.
Journal:	Cancer Lett. 2014 Oct 28;353(2):167-75.
Title:	Mutually exclusive FGFR2, HER2, and KRAS gene amplifications in gastric cancer revealed by multicolour FISH.
Author:	Das, Kakoli\|Gunasegaran, Bavani\|Tan, Iain Beehuat\|Deng, Niantao\|Lim, Kiat Hon\|Tan, Patrick
PMID:	25086186

65.
Journal:	Genome Biol. 2014 Aug 27;15(8):444.
Title:	One patient, two lesions, two oncogenic drivers of gastric cancer.
Author:	Alsinet, Clara\|Ranzani, Marco\|Adams, David J
PMID:	25222187

66.
Journal:	Mol Cancer Ther. 2014 Nov;13(11):2527-36.
Title:	Pazopanib, a novel multitargeted kinase inhibitor, shows potent in vitro antitumor activity in gastric cancer cell lines with FGFR2 amplification.
Author:	Kim, Seung Tae\|Jang, Hye-Lim\|Lee, Su Jin\|Lee, Jeeyun\|Choi, Yoon-La\|Kim, Kyoung-Mee\|Cho, Jeonghee\|Park, Se Hoon\|Park, Young Suk\|Lim, Ho Yeong\|Yashiro, Masakazu\|Kang, Won Ki\|Park, Joon Oh
PMID:	25249557

67.
Journal:	Genome Biol. 2014 Aug 27;15(8):428.
Title:	Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer.
Author:	Nadauld, Lincoln D\|Garcia, Sarah\|Natsoulis, Georges\|Bell, John M\|Miotke, Laura\|Hopmans, Erik S\|Xu, Hua\|Pai, Reetesh K\|Palm, Curt\|Regan, John F\|Chen, Hao\|Flaherty, Patrick\|Ootani, Akifumi\|Zhang, Nancy R\|Ford, James M\|Kuo, Calvin J\|Ji, Hanlee P
PMID:	25315765

68.
Journal:	World J Gastroenterol. 2014 Dec 28;20(48):18306-15.
Title:	Twist1 correlates with poor differentiation and progression in gastric adenocarcinoma via elevation of FGFR2 expression.
Author:	Zhu, Dong-Yuan\|Guo, Qi-Sen\|Li, Yan-Liang\|Cui, Bin\|Guo, Jun\|Liu, Ji-Xiao\|Li, Peng
PMID:	25561797

69.
Journal:	Gastric Cancer. 2015 Apr;18(2):227-38.
Title:	Expression profiles of HER2, EGFR, MET and FGFR2 in a large cohort of patients with gastric adenocarcinoma.
Author:	Nagatsuma, Akiko Kawano\|Aizawa, Masaki\|Kuwata, Takeshi\|Doi, Toshihiko\|Ohtsu, Atsushi\|Fujii, Hirofumi\|Ochiai, Atsushi
PMID:	24626858

70.
Journal:	Cancer Med. 2015 Jan;4(1):90-100.
Title:	Identification of EGFR expression status association with metastatic lymph node density (ND) by expression microarray analysis of advanced gastric cancer.
Author:	Ema, Akira\|Waraya, Mina\|Yamashita, Keishi\|Kokubo, Kenichi\|Kobayashi, Hirosuke\|Hoshi, Keika\|Shinkai, Yoshiko\|Kawamata, Hiroshi\|Nakamura, Kazunori\|Nishimiya, Hiroshi\|Katada, Natsuya\|Watanabe, Masahiko
PMID:	25154973

71.
Journal:	Anticancer Drugs. 2015 Apr;26(4):379-87.
Title:	The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer.
Author:	Xu, Chaochao\|Li, Wulan\|Qiu, Peihong\|Xia, Yiqun\|Du, Xiaojing\|Wang, Fen\|Shen, Lailai\|Chen, Qiuxiang\|Zhao, Yunjie\|Jin, Rong\|Wu, Jianzhang\|Liang, Guang\|Li, Xiaokun
PMID:	25521558

72.
Journal:	Oncotarget. 2015 Feb 10;6(4):2009-22.
Title:	Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer.
Author:	Chang, Jinjia\|Wang, Shanshan\|Zhang, Zhe\|Liu, Xinyang\|Wu, Zheng\|Geng, Ruixuan\|Ge, Xiaoxiao\|Dai, Congqi\|Liu, Rujiao\|Zhang, Qunling\|Li, Wenhua\|Li, Jin
PMID:	25576915

73.
Journal:	Mod Pathol. 2015 Jun;28(6):861-71.
Title:	Semi-comprehensive analysis of gene amplification in gastric cancers using multiplex ligation-dependent probe amplification and fluorescence in situ hybridization.
Author:	Ooi, Akishi\|Oyama, Takeru\|Nakamura, Ritsuko\|Tajiri, Ryosuke\|Ikeda, Hiroko\|Fushida, Sachio\|Nakamura, Hiroyuki\|Dobashi, Yoh
PMID:	25743022

74.
Journal:	Oncologist. 2015 May;20(5):499-507.
Title:	Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies.
Author:	Ali, Siraj M\|Sanford, Eric M\|Klempner, Samuel J\|Rubinson, Douglas A\|Wang, Kai\|Palma, Norma A\|Chmielecki, Juliann\|Yelensky, Roman\|Palmer, Gary A\|Morosini, Deborah\|Lipson, Doron\|Catenacci, Daniel V\|Braiteh, Fadi\|Erlich, Rachel\|Stephens, Philip J\|Ross, Jeffr
PMID:	25882375

75.
Journal:	Am J Clin Pathol. 2015 Jun;143(6):865-72.
Title:	FGFR2 Assessment in Gastric Cancer Using Quantitative Real-Time Polymerase Chain Reaction, Fluorescent In Situ Hybridization, and Immunohistochemistry.
Author:	Park, Young Soo\|Na, Young-Soon\|Ryu, Min-Hee\|Lee, Chae-Won\|Park, Hye Jin\|Lee, Ju-Kyung\|Park, Sook Ryun\|Ryoo, Baek-Yeol\|Kang, Yoon-Koo
PMID:	25972329

76.
Journal:	Gastroenterol Res Pract. 2015;2015:796380.
Title:	Therapeutic targeting of fibroblast growth factor receptors in gastric cancer.
Author:	Inokuchi, Mikito\|Fujimori, Yoshitaka\|Otsuki, Sho\|Sato, Yuya\|Nakagawa, Masatoshi\|Kojima, Kazuyuki
PMID:	26000013

77.
Journal:	PLoS One. 2015 Jul 28;10(7):e0134493.
Title:	Patient-Derived Gastric Carcinoma Xenograft Mouse Models Faithfully Represent Human Tumor Molecular Diversity.
Author:	Zhang, Tianwei\|Zhang, Lin\|Fan, Shuqiong\|Zhang, Meizhuo\|Fu, Haihua\|Liu, Yuanjie\|Yin, Xiaolu\|Chen, Hao\|Xie, Liang\|Zhang, Jingchuan\|Gavine, Paul R\|Gu, Yi\|Ni, Xingzhi\|Su, Xinying
PMID:	26217940

78.
Journal:	Anticancer Res. 2015 Sep;35(9):5055-61.
Title:	Amplification of FGFR2 Gene in Patients with Advanced Gastric Cancer Receiving Chemotherapy: Prevalence and Prognostic Significance.
Author:	Shoji, Hirokazu\|Yamada, Yasuhide\|Okita, Natsuko\|Takashima, Atsuo\|Honma, Yoshitaka\|Iwasa, Satoru\|Kato, Ken\|Hamaguchi, Tetsuya\|Shimada, Yasuhiro
PMID:	26254407

79.
Journal:	Tohoku J Exp Med. 2015 Aug;236(4):311-8.
Title:	Expression of Fibroblast Growth Factor 10 Is Correlated with Poor Prognosis in Gastric Adenocarcinoma.
Author:	Sun, Qinli\|Lin, Ping\|Zhang, Jingyu\|Li, Xiaoyan\|Yang, Liguang\|Huang, Jianguo\|Zhou, Zhongjin\|Liu, Pei\|Liu, Naiqing
PMID:	26268776

80.
Journal:	Carcinogenesis. 2015 Dec;36(12):1511-20.
Title:	Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments.
Author:	Kinoshita, Haruhito\|Yashiro, Masakazu\|Fukuoka, Tatsunari\|Hasegawa, Tsuyoshi\|Morisaki, Tamami\|Kasashima, Hiroaki\|Masuda, Go\|Noda, Satoru\|Hirakawa, Kosei
PMID:	26385890

81.
Journal:	Pathobiology. 2015;82(6):269-79.
Title:	Evaluation of Fibroblast Growth Factor Receptor 2 Expression, Heterogeneity and Clinical Significance in Gastric Cancer.
Author:	Han, Nayoung\|Kim, Min A\|Lee, Hye Seung\|Kim, Woo Ho
PMID:	26516773

82.
Journal:	Oncotarget. 2015 Dec 1;6(38):40519-34.
Title:	Identification of short-form RON as a novel intrinsic resistance mechanism for anti-MET therapy in MET-positive gastric cancer.
Author:	Wu, Zheng\|Zhang, Zhe\|Ge, Xiaoxiao\|Lin, Ying\|Dai, Congqi\|Chang, Jinjia\|Liu, Xinyang\|Geng, Ruixuan\|Wang, Chenchen\|Chen, Huan\|Sun, Menghong\|Guo, Weijian\|Li, Jin
PMID:	26528757

83.
Journal:	PLoS One. 2015 Nov 20;10(11):e0143207.
Title:	Intra-Tumoral Heterogeneity of HER2, FGFR2, cMET and ATM in Gastric Cancer: Optimizing Personalized Healthcare through Innovative Pathological and Statistical Analysis.
Author:	Ye, Peng\|Zhang, Meizhuo\|Fan, Shuqiong\|Zhang, Tianwei\|Fu, Haihua\|Su, Xinying\|Gavine, Paul R\|Liu, Qiang\|Yin, Xiaolu
PMID:	26587992

84.
Journal:	Oncol Lett. 2015 Oct;10(4):2003-2008.
Title:	Overexpression of FGFR2 contributes to inherent resistance to MET inhibitors in MET-amplified patient-derived gastric cancer xenografts.
Author:	Liu, Kai\|Song, Xilin\|Zhu, Meirong\|Ma, Heng
PMID:	26622787

85.
Journal:	Gastric Cancer. 2016 Jan;19(1):53-62.
Title:	Epithelial-mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells.
Author:	Grygielewicz, Paulina\|Dymek, Barbara\|Bujak, Anna\|Gunerka, Pawel\|Stanczak, Aleksandra\|Lamparska-Przybysz, Monika\|Wieczorek, Maciej\|Dzwonek, Karolina\|Zdzalik, Daria
PMID:	25407459

86.
Journal:	Ann Oncol. 2016 Jan;27(1):127-33.
Title:	Comprehensive analyses using next-generation sequencing and immunohistochemistry enable precise treatment in advanced gastric cancer.
Author:	Kuboki, Y\|Yamashita, S\|Niwa, T\|Ushijima, T\|Nagatsuma, A\|Kuwata, T\|Yoshino, T\|Doi, T\|Ochiai, A\|Ohtsu, A
PMID:	26489445

87.
Journal:	Med Chem. 2016;12(4):303-17.
Title:	Molecular Modeling, de novo Design and Synthesis of a Novel, Extracellular Binding Fibroblast Growth Factor Receptor 2 Inhibitor Alofanib (RPT835).
Author:	Tsimafeyeu, Ilya\|Daeyaert, Frits\|Joos, Jean-Baptiste\|Aken, Koen V\|Ludes-Meyers, John\|Byakhov, Mikhail\|Tjulandin, Sergei
PMID:	26732115

88.
Journal:	Invest New Drugs. 2016 Jun;34(3):378-93.
Title:	Targeted therapies in gastric cancer treatment: where we are and where we are going.
Author:	Tomasello, Gianluca\|Ghidini, Michele\|Liguigli, Wanda\|Ratti, Margherita\|Toppo, Laura\|Passalacqua, Rodolfo
PMID:	26873643

89.
Journal:	J Cancer Res Clin Oncol. 2016 Jun;142(6):1231-7.
Title:	Value of FGFR2 expression for advanced gastric cancer patients receiving pazopanib plus CapeOX (capecitabine and oxaliplatin).
Author:	Kim, Seung Tae\|Ahn, Soomin\|Lee, Jeeyun\|Lee, Su Jin\|Park, Se Hoon\|Park, Young Suk\|Lim, Ho Yeong\|Kang, Won Ki\|Kim, Kyoung-Mee\|Park, Joon Oh
PMID:	26983912

90.
Journal:	Genes Cancer. 2016 Jan;7(1-2):27-35.
Title:	Prognostic impact of KRAS mutant type and MET amplification in metastatic and recurrent gastric cancer patients treated with first-line S-1 plus cisplatin chemotherapy.
Author:	Matsusaka, Satoshi\|Kobunai, Takashi\|Yamamoto, Noriko\|Chin, Keisho\|Ogura, Mariko\|Tanaka, Gotaro\|Matsuoka, Kazuaki\|Ishikawa, Yuichi\|Mizunuma, Nobuyuki\|Yamaguchi, Toshiharu
PMID:	27014419

91.
Journal:	Clin Ther. 2016 Jul;38(7):1589-99.
Title:	Genomic Alterations and Targeted Therapy in Gastric and Esophageal Adenocarcinoma.
Author:	Pectasides, Eirini
PMID:	27041412

92.
Journal:	Oncotarget. 2016 May 10;7(19):28670-83.
Title:	A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth.
Author:	Park, Jihyun\|Kim, Sun Young\|Kim, Ha-Jung\|Kim, Kyoung-Mee\|Choi, Eun Young\|Kang, Myung-Soo
PMID:	27107424

93.
Journal:	Gut Liver. 2016 Sep 15;10(5):731-8.
Title:	Prognosis of Pregnancy-Associated Gastric Cancer: An Age-, Sex-, and Stage-Matched Case-Control Study.
Author:	Song, Min Jeong\|Park, Young Soo\|Song, Ho June\|Park, Se Jeong\|Ahn, Ji Yong\|Choi, Kee Don\|Lee, Gin Hyug\|Jung, Hwoon-Yong\|Yook, Jeong Hwan\|Kim, Byung Sik
PMID:	27114414

94.
Journal:	Cancer Discov. 2016 Aug;6(8):838-851.
Title:	High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial.
Author:	Pearson, Alex\|Smyth, Elizabeth\|Babina, Irina S\|Herrera-Abreu, Maria Teresa\|Tarazona, Noelia\|Peckitt, Clare\|Kilgour, Elaine\|Smith, Neil R\|Geh, Catherine\|Rooney, Claire\|Cutts, Ros\|Campbell, James\|Ning, Jian\|Fenwick, Kerry\|Swain, Amanda\|Brown, Gina\|Chua, Sue
PMID:	27179038

95.
Journal:	Cancer Res. 2016 Jul 1;76(13):3895-903.
Title:	M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers.
Author:	Ohashi, Yoshimi\|Okamura, Mutsumi\|Hirosawa, Asaka\|Tamaki, Naomi\|Akatsuka, Akinobu\|Wu, Kuo-Ming\|Choi, Hyeong-Wook\|Yoshimatsu, Kentaro\|Shiina, Isamu\|Yamori, Takao\|Dan, Shingo
PMID:	27197184

96.
Journal:	Mod Pathol. 2016 Sep;29(9):1095-103.
Title:	FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival.
Author:	Ahn, Soomin\|Lee, Jeeyun\|Hong, Mineui\|Kim, Seung Tae\|Park, Se Hoon\|Choi, Min Gew\|Lee, Jun-Ho\|Sohn, Tae Sung\|Bae, Jae Moon\|Kim, Sung\|Jung, Sin-Ho\|Kang, Won Ki\|Kim, Kyoung-Mee
PMID:	27230412

97.
Journal:	Int J Mol Med. 2016 Jul;38(1):3-15.
Title:	FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).
Author:	Katoh, Masaru
PMID:	27245147

98.
Journal:	Oncotarget. 2016 Aug 23;7(34):54445-54462.
Title:	Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation.
Author:	Saisana, Marina\|Griffin, S Michael\|May, Felicity E B
PMID:	27437872

99.
Journal:	Onco Targets Ther. 2016 Sep 27;9:5919-5929.
Title:	The coexpression and prognostic significance of c-MET, fibroblast growth factor receptor 2, and human epidermal growth factor receptor 2 in resected gastric cancer: a retrospective study.
Author:	Jia, Yong-Xu\|Li, Teng-Fei\|Zhang, Dan-Dan\|Fan, Zong-Min\|Fan, Hui-Jie\|Yan, Jie\|Chen, Li-Juan\|Tang, Hong\|Qin, Yan-Ru\|Li, Xing-Ya
PMID:	27729801

100.
Journal:	Trends Pharmacol Sci. 2016 Dec;37(12):1081-1096.
Title:	Therapeutics Targeting FGF Signaling Network in Human Diseases.
Author:	Katoh, Masaru
PMID:	27992319

101.
Journal:	Oncotarget. 2017 May 16;8(20):33844-33854.
Title:	Prognostic impact of fibroblast growth factor receptor 2 gene amplification in patients receiving fluoropyrimidine and platinum chemotherapy for metastatic and locally advanced unresectable gastric cancers.
Author:	Seo, Seyoung\|Park, Seong Joon\|Ryu, Min-Hee\|Park, Sook Ryun\|Ryoo, Baek-Yeol\|Park, Young Soo\|Na, Young-Soon\|Lee, Chae-Won\|Lee, Ju-Kyung\|Kang, Yoon-Koo
PMID:	27802183

102.
Journal:	Oncotarget. 2017 Jan 17;8(3):4888-4900.
Title:	Sprouty2 correlates with favorable prognosis of gastric adenocarcinoma via suppressing FGFR2-induced ERK phosphorylation and cancer progression.
Author:	Xu, Yunfei\|Yang, Xiaoqing\|Li, Zhen\|Li, Shuo\|Guo, Sen\|Ismail, Sayed\|Liu, Hongda\|Huang, Zhihong\|Zhang, Zongli\|Chen, Yuxin\|Sun, Qing
PMID:	28002800

103.
Journal:	World J Surg Oncol. 2017 Jan 5;15(1):2.
Title:	Different clinical significance of FGFR1-4 expression between diffuse-type and intestinal-type gastric cancer.
Author:	Inokuchi, Mikito\|Murase, Hideaki\|Otsuki, Sho\|Kawano, Tatsuyuki\|Kojima, Kazuyuki
PMID:	28056982

104.
Journal:	Oncotarget. 2017 Feb 28;8(9):15014-15022.
Title:	Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion.
Author:	Kim, Sun Young\|Ahn, Taejin\|Bang, Heejin\|Ham, Jun Soo\|Kim, Jusun\|Kim, Seung Tae\|Jang, Jiryeon\|Shim, Moonhee\|Kang, So Young\|Park, Se Hoon\|Min, Byung Hoon\|Lee, Hyuk\|Kang, Won Ki\|Kim, Kyoung-Mee\|Park, Woongyang\|Lee, Jeeyun
PMID:	28122360

105.
Journal:	Oncol Lett. 2017 Jan;13(1):215-221.
Title:	Molecular heterogeneity in the novel fusion gene APIP-FGFR2: Diversity of genomic breakpoints in gastric cancer with high-level amplifications at 11p13 and 10q26.
Author:	Okuda, Takashi\|Taki, Tomohiko\|Nishida, Kazuhiro\|Chinen, Yoshiaki\|Nagoshi, Hisao\|Sakakura, Chouhei\|Taniwaki, Masafumi
PMID:	28123544

106.
Journal:	BMC Cancer. 2017 Mar 14;17(1):191.
Title:	Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways.
Author:	Wang, Haiyong\|Lu, Jun\|Tang, Jian\|Chen, Shitu\|He, Kuifeng\|Jiang, Xiaoxia\|Jiang, Weiqin\|Teng, Lisong
PMID:	28292264

107.
Journal:	Ann Oncol. 2017 Jun 1;28(6):1207-1216.
Title:	Targeting the fibroblast growth factor receptor 2 in gastric cancer: promise or pitfall?
Author:	Hierro, C\|Alsina, M\|Sanchez, M\|Serra, V\|Rodon, J\|Tabernero, J
PMID:	28327938

108.
Journal:	Int J Oncol. 2017 May;50(5):1501-1512.
Title:	FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Author:	Huang, Tingting\|Wang, Lei\|Liu, Dian\|Li, Piao\|Xiong, Huihua\|Zhuang, Liang\|Sun, Li\|Yuan, Xianglin\|Qiu, Hong
PMID:	28339036

109.
Journal:	Oncotarget. 2017 Apr 18;8(16):26281-26287.
Title:	Circulating tumor DNA profiling by next generation sequencing reveals heterogeneity of crizotinib resistance mechanisms in a gastric cancer patient with MET amplification.
Author:	Du, Juan\|Wu, Xue\|Tong, Xiaoling\|Wang, Xiaonan\|Wei, Jia\|Yang, Yang\|Chang, Zhili\|Mao, Yu\|Shao, Yang W\|Liu, Baorui
PMID:	28460431

110.
Journal:	Transl Oncol. 2017 Aug;10(4):469-475.
Title:	Antitumor Effect of AZD4547 in a Fibroblast Growth Factor Receptor 2-Amplified Gastric Cancer Patient-Derived Cell Model.
Author:	Jang, Jiryeon\|Kim, Hee Kyung\|Bang, Heejin\|Kim, Seung Tae\|Kim, Sun Young\|Park, Se Hoon\|Lim, Ho Yeong\|Kang, Won Ki\|Lee, Jeeyun\|Kim, Kyoung-Mee
PMID:	28501555

111.
Journal:	Tumour Biol. 2017 Jun;39(6):1010428317707424.
Title:	Prognostic role of fibroblast growth factor receptor 2 in human solid tumors: A systematic review and meta-analysis.
Author:	Liu, Gang\|Xiong, Disheng\|Xiao, Rui\|Huang, Zhengjie
PMID:	28618942

112.
Journal:	Genome Med. 2017 Jun 19;9(1):57.
Title:	Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases.
Author:	Greer, Stephanie U\|Nadauld, Lincoln D\|Lau, Billy T\|Chen, Jiamin\|Wood-Bouwens, Christina\|Ford, James M\|Kuo, Calvin J\|Ji, Hanlee P
PMID:	28629429

113.
Journal:	Cold Spring Harb Mol Case Stud. 2017 Nov 21;3(6). pii: mcs.a001495.
Title:	FGFR2 amplification in colorectal adenocarcinoma.
Author:	Carter, Jamal H\|Cottrell, Catherine E\|McNulty, Samantha N\|Vigh-Conrad, Katinka A\|Lamp, Stephen\|Heusel, Jonathan W\|Duncavage, Eric J
PMID:	28835367

114.
Journal:	Int J Biol Sci. 2017 Sep 5;13(9):1163-1171.
Title:	Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer.
Author:	Lei, Haipeng\|Deng, Chu-Xia
PMID:	29104507

115.
Journal:	Oncotarget. 2017 Aug 1;8(50):87095-87106.
Title:	Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia.
Author:	Zhou, Juan\|He, Lei\|Pang, Zhijun\|Appelman, Henry D\|Kuick, Rork\|Beer, David G\|Li, Meng\|Wang, Thomas D
PMID:	29152066

116.
Journal:	Ann Oncol. 2017 Jun 1;28(6):1316-1324.
Title:	A randomized, open-label study of the efficacy and safety of AZD4547 monotherapy versus paclitaxel for the treatment of advanced gastric adenocarcinoma with FGFR2 polysomy or gene amplification.
Author:	Van Cutsem, E\|Bang, Y-J\|Mansoor, W\|Petty, R D\|Chao, Y\|Cunningham, D\|Ferry, D R\|Smith, N R\|Frewer, P\|Ratnayake, J\|Stockman, P K\|Kilgour, E\|Landers, D
PMID:	29177434

117.
Journal:	Ann Surg. 2018 Jan;267(1):114-121.
Title:	Frequent Coamplification of Receptor Tyrosine Kinase and Downstream Signaling Genes in Japanese Primary Gastric Cancer and Conversion in Matched Lymph Node Metastasis.
Author:	Silva, Arnaldo N S\|Coffa, Jordy\|Menon, Varsha\|Hewitt, Lindsay C\|Das, Kakoli\|Miyagi, Yohei\|Bottomley, Dan\|Slaney, Hayley\|Aoyama, Toru\|Mueller, Wolfram\|Arai, Tomio\|Tan, Iain B\|Deng, Niantao\|Chan, Xiu B\|Tan, Patrick\|Tsuburaya, Akira\|Sakamaki, Kentaro\|Hayden,
PMID:	27779515

118.
Journal:	Gastric Cancer. 2018 May;21(3):401-412.
Title:	In situ analysis of FGFR2 mRNA and comparison with FGFR2 gene copy number by dual-color in situ hybridization in a large cohort of gastric cancer patients.
Author:	Kuboki, Yasutoshi\|Schatz, Christoph A\|Koechert, Karl\|Schubert, Sabine\|Feng, Janine\|Wittemer-Rump, Sabine\|Ziegelbauer, Karl\|Krahn, Thomas\|Nagatsuma, Akiko Kawano\|Ochiai, Atsushi
PMID:	28852882

119.
Journal:	Acta Pharmacol Sin. 2018 Feb;39(2):243-250.
Title:	SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models.
Author:	Jiang, Xi-Fei\|Dai, Yang\|Peng, Xia\|Shen, Yan-Yan\|Su, Yi\|Wei, Man-Man\|Liu, Wei-Ren\|Ding, Zhen-Bin\|Zhang, Ao\|Shi, Ying-Hong\|Ai, Jing
PMID:	28905937

120.
Journal:	Mol Cancer Ther. 2018 Jan;17(1):232-242.
Title:	Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3beta.
Author:	Lau, Wen Min\|Teng, Eileen\|Huang, Kie Kyon\|Tan, Jin Wei\|Das, Kakoli\|Zang, Zhijiang\|Chia, Tania\|Teh, Ming\|Kono, Koji\|Yong, Wei Peng\|Shabbir, Asim\|Tay, Amy\|Phua, Niam Sin\|Tan, Patrick\|Chan, Shing Leng\|So, Jimmy Bok Yan
PMID:	28978722

121.
Journal:	J Pharmacol Exp Ther. 2018 Mar;364(3):494-503.
Title:	Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases.
Author:	Hilberg, Frank\|Tontsch-Grunt, Ulrike\|Baum, Anke\|Le, Anh T\|Doebele, Robert C\|Lieb, Simone\|Gianni, Davide\|Voss, Tilman\|Garin-Chesa, Pilar\|Haslinger, Christian\|Kraut, Norbert
PMID:	29263244

122.
Journal:	Ann Oncol. 2018 Jul 1;29(7):1605.
Title:	Targeting the fibroblast growth factor receptor 2 in gastric cancer: promise or pitfall?
Author:	Hierro, C\|Alsina, M\|Sanchez, M\|Serra, V\|Rodon, J\|Tabernero, J
PMID:	29300805

123.
Journal:	Ann Oncol. 2018 Apr 1;29(4):1037-1048.
Title:	Impact of genomic alterations on lapatinib treatment outcome and cell-free genomic landscape during HER2 therapy in HER2+ gastric cancer patients.
Author:	Kim, S T\|Banks, K C\|Pectasides, E\|Kim, S Y\|Kim, K\|Lanman, R B\|Talasaz, A\|An, J\|Choi, M G\|Lee, J H\|Sohn, T S\|Bae, J M\|Kim, S\|Park, S H\|Park, J O\|Park, Y S\|Lim, H Y\|Kim, N K D\|Park, W\|Lee, H\|Bass, A J\|Kim, K\|Kang, W K\|Lee, J
PMID:	29409051

124.
Journal:	Oncol Lett. 2018 Feb;15(2):1853-1860.
Title:	Prognostic relevance of FGFR2 expression in stage II/III gastric cancer with curative resection and S-1 chemotherapy.
Author:	Hosoda, Kei\|Yamashita, Keishi\|Ushiku, Hideki\|Ema, Akira\|Moriya, Hiromitsu\|Mieno, Hiroaki\|Washio, Marie\|Watanabe, Masahiko
PMID:	29434882

125.
Journal:	J Med Virol. 2018 Jun;90(6):1128-1133.
Title:	TM2D3 rs675436 or FGFR2 rs755793 polymorphisms and susceptibility to Epstein-Barr virus-associated tumors in Chinese Han population.
Author:	Zhang, Qianqian\|Liu, Wen\|Yang, Yang\|Zhao, Zhenzhen\|Luo, Bing
PMID:	29446487

126.
Journal:	Int J Mol Med. 2018 Aug;42(2):998-1007.
Title:	miR494 inhibits cancerinitiating cell phenotypes and reverses resistance to lapatinib by downregulating FGFR2 in HER2positive gastric cancer.
Author:	Yu, Yanxia\|Yu, Xuejuan\|Liu, Hong\|Song, Qingxun\|Yang, Yongmei
PMID:	29786108

127.
Journal:	Hum Cell. 2018 Jun 6. pii: 10.1007/s13577-018-0211-4.
Title:	The significance of scirrhous gastric cancer cell lines: the molecular characterization using cell lines and mouse models.
Author:	Yashiro, Masakazu\|Matsuoka, Tasuku\|Ohira, Masaichi
PMID:	29876827

128.
Journal:	Int J Mol Sci. 2018 Jul 9;19(7). pii: ijms19072005.
Title:	DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells.
Author:	Tajirika, Toshihiro\|Tokumaru, Yoshihisa\|Taniguchi, Kohei\|Sugito, Nobuhiko\|Matsuhashi, Nobuhisa\|Futamura, Manabu\|Yanagihara, Kazuyoshi\|Akao, Yukihiro\|Yoshida, Kazuhiro
PMID:	29987267

129.
Journal:	Int J Biochem Cell Biol. 2018 Sep;102:128-137.
Title:	Upregulation of EphB3 in gastric cancer with acquired resistance to a FGFR inhibitor.
Author:	Lee, Suk-Young\|Na, Yoo Jin\|Jeong, Yoon A\|Kim, Jung Lim\|Oh, Sang Cheul\|Lee, Dae-Hee
PMID:	30044964

130.
Journal:	Mol Cancer Ther. 2018 Jul 25. pii: 1535-7163.MCT-17-1022.
Title:	Acquired JHDM1D-BRAF fusion confers resistance to FGFR inhibition in FGFR2- amplified gastric cancer.
Author:	Sase, Hitoshi\|Nakanishi, Yoshito\|Aida, Satoshi\|Horiguchi-Takei, Kana\|Akiyama, Nukinori\|Fujii, Toshihiko\|Sakata, Kiyoaki\|Mio, Toshiyuki\|Aoki, Masahiro\|Ishii, Nobuya
PMID:	30045926

131.
Journal:	Genes Chromosomes Cancer. 2018 Sep 21.
Title:	Somatic mutational profiles of stage II and III gastric cancer according to tumor microenvironment immune type.
Author:	Koh, Jiwon\|Nam, Soo Kyung\|Roh, Hanseong\|Kim, Jonghyuk\|Lee, Byung-Chul\|Kim, Jin Won\|Ahn, Sang-Hoon\|Park, Do Joong\|Kim, Hyung-Ho\|Park, Kyoung Un\|Chung, Jin Haeng\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	30239046

132.
Journal:	Cell Physiol Biochem. 2018 Oct 24;50(4):1332-1345.
Title:	FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway.
Author:	Huang, Tingting\|Liu, Dian\|Wang, Yihua\|Li, Piao\|Sun, Li\|Xiong, Huihua\|Dai, Yuhong\|Zou, Man\|Yuan, Xianglin\|Qiu, Hong
PMID:	30355943