Primary Site >> Liver Cancer
Gene >> FGF19
| 1. | |||||||||||
| Journal: | Am J Pathol. 2002 Jun;160(6):2295-307. | ||||||||||
| Title: | A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice. | ||||||||||
| Author: | Nicholes, Katrina|Guillet, Susan|Tomlinson, Elizabeth|Hillan, Kenneth|Wright, Barbara|Frantz, Gretchen D|Pham, Thinh A|Dillard-Telm, Lisa|Tsai, Siao Ping|Stephan, Jean-Philippe|Stinson, Jeremy|Stewart, Timothy|French, Dorothy M | ||||||||||
| PMID: | 12057932 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Oncol. 2005 Jul;27(1):281-5. | ||||||||||
| Title: | Comparative genomics on mammalian Fgf3-Fgf4 locus. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 15942670 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2008 Jan 3;27(1):85-97. | ||||||||||
| Title: | Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. | ||||||||||
| Author: | Desnoyers, L R|Pai, R|Ferrando, R E|Hotzel, K|Le, T|Ross, J|Carano, R|D'Souza, A|Qing, J|Mohtashemi, I|Ashkenazi, A|French, D M | ||||||||||
| PMID: | 17599042 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Pharm. 2008 Jan-Feb;5(1):42-8. | ||||||||||
| Title: | Mini-review: endocrine actions of fibroblast growth factor 19. | ||||||||||
| Author: | Jones, Stacey | ||||||||||
| PMID: | 18179175 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2010 Feb 19;285(8):5165-70. | ||||||||||
| Title: | FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation. | ||||||||||
| Author: | Wu, Xinle|Ge, Hongfei|Lemon, Bryan|Vonderfecht, Steven|Weiszmann, Jennifer|Hecht, Randy|Gupte, Jamila|Hager, Todd|Wang, Zhulun|Lindberg, Richard|Li, Yang | ||||||||||
| PMID: | 20018895 | ||||||||||
| 6. | |||||||||||
| Journal: | J Biol Chem. 2010 Sep 24;285(39):30069-78. | ||||||||||
| Title: | Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation. | ||||||||||
| Author: | Luo, Yongde|Yang, Chaofeng|Lu, Weiqin|Xie, Rui|Jin, Chengliu|Huang, Peng|Wang, Fen|McKeehan, Wallace L | ||||||||||
| PMID: | 20657013 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Cell. 2011 Mar 8;19(3):347-58. | ||||||||||
| Title: | Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening. | ||||||||||
| Author: | Sawey, Eric T|Chanrion, Maia|Cai, Chunlin|Wu, Guanming|Zhang, Jianping|Zender, Lars|Zhao, Alice|Busuttil, Ronald W|Yee, Herman|Stein, Lincoln|French, Dorothy M|Finn, Richard S|Lowe, Scott W|Powers, Scott | ||||||||||
| PMID: | 21397858 | ||||||||||
| 8. | |||||||||||
| Journal: | Toxicol Sci. 2012 Apr;126(2):446-56. | ||||||||||
| Title: | Antibody-mediated inhibition of fibroblast growth factor 19 results in increased bile acids synthesis and ileal malabsorption of bile acids in cynomolgus monkeys. | ||||||||||
| Author: | Pai, Rama|French, Dorothy|Ma, Ning|Hotzel, Kathy|Plise, Emile|Salphati, Laurent|Setchell, Kenneth D R|Ware, Joseph|Lauriault, Veronique|Schutt, Leah|Hartley, Dylan|Dambach, Donna | ||||||||||
| PMID: | 22268002 | ||||||||||
| 9. | |||||||||||
| Journal: | BMC Cancer. 2012 Feb 6;12:56. | ||||||||||
| Title: | Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma. | ||||||||||
| Author: | Miura, Seiki|Mitsuhashi, Noboru|Shimizu, Hiroaki|Kimura, Fumio|Yoshidome, Hiroyuki|Otsuka, Masayuki|Kato, Atsushi|Shida, Takashi|Okamura, Daiki|Miyazaki, Masaru | ||||||||||
| PMID: | 22309595 | ||||||||||
| 10. | |||||||||||
| Journal: | Adv Exp Med Biol. 2012;728:183-94. | ||||||||||
| Title: | FGF19 and cancer. | ||||||||||
| Author: | Lin, Benjamin C|Desnoyers, Luc R | ||||||||||
| PMID: | 22396170 | ||||||||||
| 11. | |||||||||||
| Journal: | Adv Exp Med Biol. 2012;728:195-213. | ||||||||||
| Title: | Understanding the structure-function relationship between FGF19 and its mitogenic and metabolic activities. | ||||||||||
| Author: | Wu, Xinle|Li, Yang | ||||||||||
| PMID: | 22396171 | ||||||||||
| 12. | |||||||||||
| Journal: | PLoS One. 2012;7(5):e36713. | ||||||||||
| Title: | Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models. | ||||||||||
| Author: | French, Dorothy M|Lin, Benjamin C|Wang, Manping|Adams, Camellia|Shek, Theresa|Hotzel, Kathy|Bolon, Brad|Ferrando, Ronald|Blackmore, Craig|Schroeder, Kurt|Rodriguez, Luis A|Hristopoulos, Maria|Venook, Rayna|Ashkenazi, Avi|Desnoyers, Luc R | ||||||||||
| PMID: | 22615798 | ||||||||||
| 13. | |||||||||||
| Journal: | PLoS One. 2012;7(12):e52711. | ||||||||||
| Title: | Regulation of amphiregulin gene expression by beta-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system. | ||||||||||
| Author: | Latasa, Maria U|Salis, Fabiana|Urtasun, Raquel|Garcia-Irigoyen, Oihane|Elizalde, Maria|Uriarte, Iker|Santamaria, Monica|Feo, Francesco|Pascale, Rosa M|Prieto, Jesus|Berasain, Carmen|Avila, Matias A | ||||||||||
| PMID: | 23285165 | ||||||||||
| 14. | |||||||||||
| Journal: | Dig Dis Sci. 2013 Jul;58(7):1916-22. | ||||||||||
| Title: | Expression of fibroblast growth factor 19 is associated with recurrence and poor prognosis of hepatocellular carcinoma. | ||||||||||
| Author: | Hyeon, Jiyeon|Ahn, Soomin|Lee, Jae Jun|Song, Dae Hyun|Park, Cheol-Keun | ||||||||||
| PMID: | 23456506 | ||||||||||
| 15. | |||||||||||
| Journal: | World J Gastroenterol. 2013 Dec 21;19(47):8873-9. | ||||||||||
| Title: | Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. | ||||||||||
| Author: | Gu, De-Leung|Chen, Yen-Hsieh|Shih, Jou-Ho|Lin, Chi-Hung|Jou, Yuh-Shan|Chen, Chian-Feng | ||||||||||
| PMID: | 24379610 | ||||||||||
| 16. | |||||||||||
| Journal: | Liver Int. 2014 Jul;34(6):e1-9. | ||||||||||
| Title: | Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations. | ||||||||||
| Author: | Mellor, Howard R | ||||||||||
| PMID: | 24393342 | ||||||||||
| 17. | |||||||||||
| Journal: | Curr Opin Lipidol. 2014 Apr;25(2):140-7. | ||||||||||
| Title: | Regulation of bile acid homeostasis by the intestinal Diet1-FGF15/19 axis. | ||||||||||
| Author: | Reue, Karen|Lee, Jessica M|Vergnes, Laurent | ||||||||||
| PMID: | 24535283 | ||||||||||
| 18. | |||||||||||
| Journal: | Clin Cancer Res. 2014 Apr 15;20(8):2072-9. | ||||||||||
| Title: | Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial design. | ||||||||||
| Author: | Llovet, Josep M|Hernandez-Gea, Virginia | ||||||||||
| PMID: | 24589894 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Res. 2014 Jun 15;74(12):3306-16. | ||||||||||
| Title: | Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19. | ||||||||||
| Author: | Zhou, Mei|Wang, Xueyan|Phung, Van|Lindhout, Darrin A|Mondal, Kalyani|Hsu, Jer-Yuan|Yang, Hong|Humphrey, Mark|Ding, Xunshan|Arora, Taruna|Learned, R Marc|DePaoli, Alex M|Tian, Hui|Ling, Lei | ||||||||||
| PMID: | 24728076 | ||||||||||
| 20. | |||||||||||
| Journal: | Hepatology. 2014 Dec;60(6):1972-82. | ||||||||||
| Title: | Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification. | ||||||||||
| Author: | Ahn, Sung-Min|Jang, Se Jin|Shim, Ju Hyun|Kim, Deokhoon|Hong, Seung-Mo|Sung, Chang Ohk|Baek, Daehyun|Haq, Farhan|Ansari, Adnan Ahmad|Lee, Sun Young|Chun, Sung-Min|Choi, Seongmin|Choi, Hyun-Jeung|Kim, Jongkyu|Kim, Sukjun|Hwang, Shin|Lee, Young-Joo|Lee, Jong | ||||||||||
| PMID: | 24798001 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2014 May 30;5(10):3012-22. | ||||||||||
| Title: | Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing. | ||||||||||
| Author: | Janku, Filip|Kaseb, Ahmed O|Tsimberidou, Apostolia M|Wolff, Robert A|Kurzrock, Razelle | ||||||||||
| PMID: | 24931142 | ||||||||||
| 22. | |||||||||||
| Journal: | Diseases. 2015 Oct 28;3(4):294-305. | ||||||||||
| Title: | Targeting FGF19/FGFR4 Pathway: A Novel Therapeutic Strategy for Hepatocellular Carcinoma. | ||||||||||
| Author: | Repana, Dimitra|Ross, Paul | ||||||||||
| PMID: | 28943626 | ||||||||||
| 23. | |||||||||||
| Journal: | Clin Res Hepatol Gastroenterol. 2015 Sep;39 Suppl 1:S80-5. | ||||||||||
| Title: | New molecular therapies for hepatocellular carcinoma. | ||||||||||
| Author: | Torrecilla, S|Llovet, J M | ||||||||||
| PMID: | 26206572 | ||||||||||
| 24. | |||||||||||
| Journal: | Gastroenterology. 2015 Oct;149(5):1226-1239.e4. | ||||||||||
| Title: | Genetic Landscape and Biomarkers of Hepatocellular Carcinoma. | ||||||||||
| Author: | Zucman-Rossi, Jessica|Villanueva, Augusto|Nault, Jean-Charles|Llovet, Josep M | ||||||||||
| PMID: | 26099527 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Discov. 2015 Apr;5(4):355-7. | ||||||||||
| Title: | Paralog-Specific Kinase Inhibition of FGFR4: Adding to the Arsenal of Anti-FGFR Agents. | ||||||||||
| Author: | Packer, Leisl M|Pollock, Pamela M | ||||||||||
| PMID: | 25847957 | ||||||||||
| 26. | |||||||||||
| Journal: | Nat Genet. 2015 May;47(5):505-511. | ||||||||||
| Title: | Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets. | ||||||||||
| Author: | Schulze, Kornelius|Imbeaud, Sandrine|Letouze, Eric|Alexandrov, Ludmil B|Calderaro, Julien|Rebouissou, Sandra|Couchy, Gabrielle|Meiller, Clement|Shinde, Jayendra|Soysouvanh, Frederic|Calatayud, Anna-Line|Pinyol, Roser|Pelletier, Laura|Balabaud, Charles|Lau | ||||||||||
| PMID: | 25822088 | ||||||||||
| 27. | |||||||||||
| Journal: | Hepatology. 2015 Oct;62(4):1324. | ||||||||||
| Title: | Targeting FGF19 binding to its receptor system: a novel therapeutic approach for hepatocellular carcinoma. | ||||||||||
| Author: | Panera, Nadia|Ceccarelli, Sara|Nobili, Valerio|Alisi, Anna | ||||||||||
| PMID: | 25677789 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Discov. 2015 Apr;5(4):424-37. | ||||||||||
| Title: | First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway. | ||||||||||
| Author: | Hagel, Margit|Miduturu, Chandra|Sheets, Michael|Rubin, Nooreen|Weng, Weifan|Stransky, Nicolas|Bifulco, Neil|Kim, Joseph L|Hodous, Brian|Brooijmans, Natasja|Shutes, Adam|Winter, Christopher|Lengauer, Christoph|Kohl, Nancy E|Guzi, Timothy | ||||||||||
| PMID: | 25776529 | ||||||||||
| 29. | |||||||||||
| Journal: | Int J Cancer. 2015 May 15;136(10):2469-75. | ||||||||||
| Title: | Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development. | ||||||||||
| Author: | Uriarte, Iker|Latasa, M Ujue|Carotti, Simone|Fernandez-Barrena, Maite G|Garcia-Irigoyen, Oihane|Elizalde, Maria|Urtasun, Raquel|Vespasiani-Gentilucci, Umberto|Morini, Sergio|de Mingo, Alvaro|Mari, Montserrat|Corrales, Fernando J|Prieto, Jesus|Berasain, Ca | ||||||||||
| PMID: | 25346390 | ||||||||||
| 30. | |||||||||||
| Journal: | Expert Opin Ther Targets. 2015 May;19(5):675-85. | ||||||||||
| Title: | Targeting fibroblast growth factor 19 in liver disease: a potential biomarker and therapeutic target. | ||||||||||
| Author: | Liu, Wen-Yue|Xie, Dong-Mei|Zhu, Gui-Qi|Huang, Gui-Qian|Lin, Yi-Qian|Wang, Li-Ren|Shi, Ke-Qing|Hu, Bin|Braddock, Martin|Chen, Yong-Ping|Zheng, Ming-Hua | ||||||||||
| PMID: | 25547779 | ||||||||||
| 31. | |||||||||||
| Journal: | Nat Commun. 2015 Jan 22;6:6087. | ||||||||||
| Title: | Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Sia, Daniela|Losic, Bojan|Moeini, Agrin|Cabellos, Laia|Hao, Ke|Revill, Kate|Bonal, Dennis|Miltiadous, Oriana|Zhang, Zhongyang|Hoshida, Yujin|Cornella, Helena|Castillo-Martin, Mireia|Pinyol, Roser|Kasai, Yumi|Roayaie, Sasan|Thung, Swan N|Fuster, Josep|Schw | ||||||||||
| PMID: | 25608663 | ||||||||||
| 32. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 22;7(12):13575-86. | ||||||||||
| Title: | FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3beta/beta- catenin signaling cascade via FGFR4 activation. | ||||||||||
| Author: | Zhao, Huakan|Lv, Fenglin|Liang, Guizhao|Huang, Xiaobin|Wu, Gang|Zhang, Wenfa|Yu, Le|Shi, Lei|Teng, Yong | ||||||||||
| PMID: | 26498355 | ||||||||||
| 33. | |||||||||||
| Journal: | Hepatology. 2016 Oct;64(4):1289-301. | ||||||||||
| Title: | Mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast growth factor 19 in hepatoma cells. | ||||||||||
| Author: | Wan, Zhi Yi|Tian, Johann Shane|Tan, Hayden Weng Siong|Chow, Ai Lee|Sim, Arthur Yi Loong|Ban, Kenneth Hon Kim|Long, Yun Chau | ||||||||||
| PMID: | 27178107 | ||||||||||
| 34. | |||||||||||
| Journal: | Int J Oncol. 2016 Aug;49(2):589-602. | ||||||||||
| Title: | Whole-genome DNA methylation and hydroxymethylation profiling for HBV-related hepatocellular carcinoma. | ||||||||||
| Author: | Ye, Chao|Tao, Ran|Cao, Qingyi|Zhu, Danhua|Wang, Yini|Wang, Jie|Lu, Juan|Chen, Ermei|Li, Lanjuan | ||||||||||
| PMID: | 27221337 | ||||||||||
| 35. | |||||||||||
| Journal: | Genes Cancer. 2016 Mar;7(3-4):125-35. | ||||||||||
| Title: | FGF19 functions as autocrine growth factor for hepatoblastoma. | ||||||||||
| Author: | Elzi, David J|Song, Meihua|Blackman, Barron|Weintraub, Susan T|Lopez-Terrada, Dolores|Chen, Yidong|Tomlinson, Gail E|Shiio, Yuzuru | ||||||||||
| PMID: | 27382436 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 2;7(31):49091-49098. | ||||||||||
| Title: | Increased FGF19 copy number is frequently detected in hepatocellular carcinoma with a complete response after sorafenib treatment. | ||||||||||
| Author: | Kaibori, Masaki|Sakai, Kazuko|Ishizaki, Morihiko|Matsushima, Hideyuki|De Velasco, Marco A|Matsui, Kosuke|Iida, Hiroya|Kitade, Hiroaki|Kwon, A-Hon|Nagano, Hiroaki|Wada, Hiroshi|Haji, Seiji|Tsukamoto, Tadashi|Kanazawa, Akishige|Takeda, Yutaka|Takemura, Shig | ||||||||||
| PMID: | 27384874 | ||||||||||
| 37. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 9;7(32):52329-52339. | ||||||||||
| Title: | Up-regulation of fibroblast growth factor 19 and its receptor associates with progression from fatty liver to hepatocellular carcinoma. | ||||||||||
| Author: | Li, Yan|Zhang, Weizhong|Doughtie, Anne|Cui, Guozhen|Li, Xuanyi|Pandit, Harshul|Yang, Yingbin|Li, Suping|Martin, Robert | ||||||||||
| PMID: | 27447573 | ||||||||||
| 38. | |||||||||||
| Journal: | Hepatol Commun. 2017 Oct 16;1(10):1024-1042. | ||||||||||
| Title: | Engineered FGF19 eliminates bile acid toxicity and lipotoxicity leading to resolution of steatohepatitis and fibrosis in mice. | ||||||||||
| Author: | Zhou, Mei|Learned, R Marc|Rossi, Stephen J|DePaoli, Alex M|Tian, Hui|Ling, Lei | ||||||||||
| PMID: | 29404440 | ||||||||||
| 39. | |||||||||||
| Journal: | Cancer Res. 2017 Dec 15;77(24):6999-7013. | ||||||||||
| Title: | H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma. | ||||||||||
| Author: | Joshi, Jaya Julie|Coffey, Heather|Corcoran, Erik|Tsai, Jennifer|Huang, Chia-Ling|Ichikawa, Kana|Prajapati, Sudeep|Hao, Ming-Hong|Bailey, Suzanna|Wu, Jeremy|Rimkunas, Victoria|Karr, Craig|Subramanian, Vanitha|Kumar, Pavan|MacKenzie, Crystal|Hurley, Raelene | ||||||||||
| PMID: | 29247039 | ||||||||||
| 40. | |||||||||||
| Journal: | Cancer Res. 2017 Nov 15;77(22):6215-6225. | ||||||||||
| Title: | FGF19 Protects Hepatocellular Carcinoma Cells against Endoplasmic Reticulum Stress via Activation of FGFR4-GSK3beta-Nrf2 Signaling. | ||||||||||
| Author: | Teng, Yong|Zhao, Huakan|Gao, Lixia|Zhang, Wenfa|Shull, Austin Y|Shay, Chloe | ||||||||||
| PMID: | 28951455 | ||||||||||
| 41. | |||||||||||
| Journal: | J Hepatol. 2017 Oct;67(4):727-738. | ||||||||||
| Title: | Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification. | ||||||||||
| Author: | Calderaro, Julien|Couchy, Gabrielle|Imbeaud, Sandrine|Amaddeo, Giuliana|Letouze, Eric|Blanc, Jean-Frederic|Laurent, Christophe|Hajji, Yacine|Azoulay, Daniel|Bioulac-Sage, Paulette|Nault, Jean-Charles|Zucman-Rossi, Jessica | ||||||||||
| PMID: | 28532995 | ||||||||||
| 42. | |||||||||||
| Journal: | Nat Commun. 2017 May 16;8:15433. | ||||||||||
| Title: | Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis. | ||||||||||
| Author: | Zhou, Mei|Yang, Hong|Learned, R Marc|Tian, Hui|Ling, Lei | ||||||||||
| PMID: | 28508871 | ||||||||||
| 43. | |||||||||||
| Journal: | Dig Dis. 2017;35(3):158-165. | ||||||||||
| Title: | Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis. | ||||||||||
| Author: | Alvarez-Sola, Gloria|Uriarte, Iker|Latasa, M Ujue|Urtasun, Raquel|Barcena-Varela, Marina|Elizalde, Maria|Jimenez, Maddalen|Rodriguez-Ortigosa, Carlos M|Corrales, Fernando J|Fernandez-Barrena, Maite G|Berasain, Carmen|Avila, Matias A | ||||||||||
| PMID: | 28249259 | ||||||||||
| 44. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):38592-38601. | ||||||||||
| Title: | Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Yoo, Changhoon|Kang, Jihoon|Kim, Deokhoon|Kim, Kyu-Pyo|Ryoo, Baek-Yeol|Hong, Seung-Mo|Hwang, Jung Jin|Jeong, Seong-Yun|Hwang, Shin|Kim, Ki-Hun|Lee, Young-Joo|Hoeflich, Klaus P|Schmidt-Kittler, Oleg|Miller, Stephen|Choi, Eun Kyung | ||||||||||
| PMID: | 28445152 | ||||||||||
| 45. | |||||||||||
| Journal: | J Hepatol. 2017 Jun;66(6):1182-1192. | ||||||||||
| Title: | Mouse species-specific control of hepatocarcinogenesis and metabolism by FGF19/FGF15. | ||||||||||
| Author: | Zhou, Mei|Luo, Jian|Chen, Michael|Yang, Hong|Learned, R Marc|DePaoli, Alex M|Tian, Hui|Ling, Lei | ||||||||||
| PMID: | 28189755 | ||||||||||
| 46. | |||||||||||
| Journal: | PLoS One. 2017 Feb 8;12(2):e0171185. | ||||||||||
| Title: | Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation. | ||||||||||
| Author: | Massafra, Vittoria|Milona, Alexandra|Vos, Harmjan R|Burgering, Boudewijn M T|van Mil, Saskia W C | ||||||||||
| PMID: | 28178326 | ||||||||||
| 47. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2017 Jan 9;36(1):8. | ||||||||||
| Title: | FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib. | ||||||||||
| Author: | Gao, Lixia|Wang, Xuli|Tang, Yaoliang|Huang, Shuang|Hu, Chien-An Andy|Teng, Yong | ||||||||||
| PMID: | 28069043 | ||||||||||
| 48. | |||||||||||
| Journal: | Mol Cancer Ther. 2017 Jan;16(1):68-75. | ||||||||||
| Title: | ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma. | ||||||||||
| Author: | Futami, Takashi|Okada, Hidetsugu|Kihara, Rumi|Kawase, Tatsuya|Nakayama, Ayako|Suzuki, Tomoyuki|Kameda, Minoru|Shindoh, Nobuaki|Terasaka, Tadashi|Hirano, Masaaki|Kuromitsu, Sadao | ||||||||||
| PMID: | 27837028 | ||||||||||
| 49. | |||||||||||
| Journal: | Gastroenterology. 2017 Jan;152(1):232-242.e4. | ||||||||||
| Title: | Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents. | ||||||||||
| Author: | Gao, Qiang|Wang, Zhi-Chao|Duan, Meng|Lin, Yi-Hui|Zhou, Xue-Ya|Worthley, Daniel L|Wang, Xiao-Ying|Niu, Gang|Xia, Yuchao|Deng, Minghua|Liu, Long-Zi|Shi, Jie-Yi|Yang, Liu-Xiao|Zhang, Shu|Ding, Zhen-Bin|Zhou, Jian|Liang, Chun-Min|Cao, Ya|Xiong, Lei|Xi, Ruibin | ||||||||||
| PMID: | 27639803 | ||||||||||
| 50. | |||||||||||
| Journal: | Cell Oncol (Dordr). 2018 Feb;41(1):85-91. | ||||||||||
| Title: | Implications of FGF19 on sorafenib-mediated nitric oxide production in hepatocellular carcinoma cells - a short report. | ||||||||||
| Author: | Gao, Lixia|Shay, Chloe|Lv, Fenglin|Wang, Xuli|Teng, Yong | ||||||||||
| PMID: | 28983785 | ||||||||||
| 51. | |||||||||||
| Journal: | Gene Expr. 2018 May 18;18(2):103-113. | ||||||||||
| Title: | Endocrine Adiponectin-FGF15/19 Axis in Ethanol-Induced Inflammation and Alcoholic Liver Injury. | ||||||||||
| Author: | You, Min|Zhou, Zhou|Daniels, Michael|Jogasuria, Alvin | ||||||||||
| PMID: | 29096734 | ||||||||||
| 52. | |||||||||||
| Journal: | Toxicol Sci. 2018 May 1;163(1):265-278. | ||||||||||
| Title: | Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation. | ||||||||||
| Author: | Schadt, Heiko S|Wolf, Armin|Mahl, Joerg Andreas|Wuersch, Kuno|Couttet, Philippe|Schwald, Marianne|Fischer, Audrey|Lienard, Mathilde|Emotte, Corinne|Teng, Chi-Hse|Skuba, Elizabeth|Richardson, Terrilyn A|Manenti, Luigi|Weiss, Andreas|Graus Porta, Diana|Fair | ||||||||||
| PMID: | 29432567 | ||||||||||
| 53. | |||||||||||
| Journal: | Future Oncol. 2018 Mar;14(6):553-566. | ||||||||||
| Title: | Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma. | ||||||||||
| Author: | DeLeon, Thomas T|Ahn, Daniel H|Bogenberger, James M|Anastasiadis, Panos Z|Arora, Mansi|Ramanathan, Ramesh K|Aqel, Bashar A|Vasmatzis, George|Truty, Mark J|Oklu, Rahmi|Bekaii-Saab, Tanios S|Borad, Mitesh J | ||||||||||
| PMID: | 29460642 | ||||||||||
| 54. | |||||||||||
| Journal: | J Physiol Biochem. 2018 May;74(2):247-260. | ||||||||||
| Title: | The ileal FGF15/19 to hepatic FGFR4 axis regulates liver regeneration after partial hepatectomy in mice. | ||||||||||
| Author: | Li, Qiang|Zhao, Qiang|Zhang, Chuanzhao|Zhang, Peng|Hu, Anbin|Zhang, Longjuan|Schroder, Paul M|Ma, Yi|Guo, Zhiyong|Zhu, Xiaofeng|He, Xiaoshun | ||||||||||
| PMID: | 29468415 | ||||||||||
| 55. | |||||||||||
| Journal: | Oncotarget. 2017 Nov 20;9(15):12471-12478. | ||||||||||
| Title: | Research progress on the forkhead box C1. | ||||||||||
| Author: | Wang, Jinhua|Li, Wan|Zheng, Xiangjin|Pang, Xiaocong|Du, Guanhua | ||||||||||
| PMID: | 29552326 | ||||||||||
| 56. | |||||||||||
| Journal: | Cancer Med. 2018 Jun;7(6):2641-2653. | ||||||||||
| Title: | Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma models. | ||||||||||
| Author: | Matsuki, Masahiro|Hoshi, Taisuke|Yamamoto, Yuji|Ikemori-Kawada, Megumi|Minoshima, Yukinori|Funahashi, Yasuhiro|Matsui, Junji | ||||||||||
| PMID: | 29733511 | ||||||||||
| 57. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2018 Jul 4;37(1):136. | ||||||||||
| Title: | Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver. | ||||||||||
| Author: | Cui, Guozhen|Martin, Robert C|Jin, Hang|Liu, Xingkai|Pandit, Harshul|Zhao, Hengjun|Cai, Lu|Zhang, Ping|Li, Wei|Li, Yan | ||||||||||
| PMID: | 29973237 | ||||||||||
| 58. | |||||||||||
| Journal: | Curr Opin Pharmacol. 2018 Sep 14;43:93-98. | ||||||||||
| Title: | The gut-liver axis in hepatocarcinoma: a focus on the nuclear receptor FXR and the enterokine FGF19. | ||||||||||
| Author: | Piglionica, Marilidia|Cariello, Marica|Moschetta, Antonio | ||||||||||
| PMID: | 30223181 | ||||||||||
| 59. | |||||||||||
| Journal: | Clin Cancer Res. 2018 Oct 29. pii: 1078-0432.CCR-18-2293. | ||||||||||
| Title: | Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next Generation Sequencing for Matching Patients to Targeted and Immune Therapies. | ||||||||||
| Author: | Harding, James J|Nandakumar, Subhiksha|Armenia, Joshua|Khalil, Danny N|Albano, Melanie|Ly, Michele|Shia, Jinru|Hechtman, Jaclyn F|Kundra, Ritika|El Dika, Imane|Do, Richard K|Sun, Yichao|Kingham, T Peter|D'Angelica, Michael I|Berger, Michael F|Hyman, David | ||||||||||
| PMID: | 30373752 | ||||||||||