Primary Site >> Colorectal Cancer

Gene >> ERCC1

Journal: Cancer Res. 1998 Feb 15;58(4):604-8.
Title: Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.
Author: Shen, M R|Jones, I M|Mohrenweiser, H
PMID: 9485007
Journal: Clin Cancer Res. 2000 Mar;6(3):773-81.
Title: Expression of ERCC1 antisense RNA abrogates gemicitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair.
Author: Yang, L Y|Li, L|Jiang, H|Shen, Y|Plunkett, W
PMID: 10741696
Journal: Oncology (Williston Park). 2001 Mar;15(3 Suppl 6):52-60.
Title: Novel approaches in the treatment of non-small-cell lung cancer.
Author: Rosell, R|Sanchez, J M|Taron, M|O'Brate, A|Gutierrez, J L|Monzo, M|Felip, E|Sanchez, J J|Alberola, V
PMID: 11301850
Journal: Anticancer Drugs. 2001 Oct;12(9):741-51.
Title: Combination of oxaliplatin and irinotecan on human colon cancer cell lines: activity in vitro and in vivo.
Author: Guichard, S|Arnould, S|Hennebelle, I|Bugat, R|Canal, P
PMID: 11593056
Journal: J Clin Oncol. 2001 Dec 1;19(23):4298-304.
Title: ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy.
Author: Shirota, Y|Stoehlmacher, J|Brabender, J|Xiong, Y P|Uetake, H|Danenberg, K D|Groshen, S|Tsao-Wei, D D|Danenberg, P V|Lenz, H J
PMID: 11731512
Journal: Semin Oncol. 2002 Apr;29(2 Suppl 5):23-9.
Title: Pemetrexed combination therapy in the treatment of non-small cell lung cancer.
Author: Rosell, Rafael|Crino, Lucio
PMID: 12023789
Journal: Cancer Res. 2002 Aug 1;62(15):4339-45.
Title: A sucrose-rich diet induces mutations in the rat colon.
Author: Dragsted, Lars O|Daneshvar, Bahram|Vogel, Ulla|Autrup, Herman N|Wallin, Hakan|Risom, Lotte|Moller, Peter|Molck, Anne M|Hansen, Max|Poulsen, Henrik E|Loft, Steffen
PMID: 12154038
Journal: Pharmacogenomics. 2002 Nov;3(6):763-80.
Title: Pharmacogenomic strategies for developing customized chemotherapy in non-small cell lung cancer.
Author: Sarries, Carme|Haura, Eric B|Roig, Barbara|Taron, Miquel|Abad, Albert|Scagliotti, Giorgio|Rosell, Rafael
PMID: 12437479
Journal: Lung Cancer. 2002 Dec;38 Suppl 4:43-9.
Title: Molecular markers and targeted therapy with novel agents: prospects in the treatment of non-small cell lung cancer.
Author: Rosell, Rafael|Fossella, Frank|Milas, Luka
PMID: 12480194
Journal: Eur J Cancer. 2003 Jan;39(1):112-9.
Title: Cellular determinants of oxaliplatin sensitivity in colon cancer cell lines.
Author: Arnould, S|Hennebelle, I|Canal, P|Bugat, R|Guichard, S
PMID: 12504667
Journal: Am J Pharmacogenomics. 2003;3(2):73-88.
Title: Implications of genetic testing in the management of colorectal cancer.
Author: Stoehlmacher, Jan|Lenz, Heinz-Josef
PMID: 12749725
Journal: Br J Cancer. 2003 Jul 21;89(2):333-7.
Title: Lack of involvement of nucleotide excision repair gene polymorphisms in colorectal cancer.
Author: Mort, R|Mo, L|McEwan, C|Melton, D W
PMID: 12865926
Journal: Arch Toxicol. 2003 Nov;77(11):651-6.
Title: Dietary elevated sucrose modulation of diesel-induced genotoxicity in the colon and liver of Big Blue rats.
Author: Risom, Lotte|Moller, Peter|Hansen, Max|Autrup, Herman|Bornholdt, Jette|Vogel, Ulla|Wallin, Hakan|Poulsen, Henrik E|Dragsted, Lars O|Loft, Steffen
PMID: 12937889
Journal: Clin Adv Hematol Oncol. 2003 Mar;1(3):162-6.
Title: ERCC1 gene polymorphism as a predictor for clinical outcome in advanced colorectal cancer patients treated with platinum-based chemotherapy.
Author: Park, David J|Zhang, Wu|Stoehlmacher, Jan|Tsao-Wei, Denice|Groshen, Susan|Gil, Ji|Yun, Jim|Sones, Erin|Mallik, Nalin|Lenz, Heinz-Josef
PMID: 16224397
Journal: Clin Cancer Res. 2004 Mar 15;10(6):2158-67.
Title: Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan.
Author: Boyer, John|McLean, Estelle G|Aroori, Somaiah|Wilson, Peter|McCulla, Andrea|Carey, P Declan|Longley, Daniel B|Johnston, Patrick G
PMID: 15041737
Journal: Br J Cancer. 2004 Jul 19;91(2):344-54.
Title: A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer.
Author: Stoehlmacher, J|Park, D J|Zhang, W|Yang, D|Groshen, S|Zahedy, S|Lenz, H-J
PMID: 15213713
Journal: Cancer Invest. 2004;22(5):762-73.
Title: Tailored chemotherapy for colorectal cancer: a new approach to therapy.
Author: Iqbal, Syma|Stoehlmacher, Jan|Lenz, Heinz-Josef
PMID: 15581057
Journal: Br J Cancer. 2005 Jan 31;92(2):259-64.
Title: Unfavourable expression of pharmacologic markers in mucinous colorectal cancer.
Author: Glasgow, S C|Yu, J|Carvalho, L P|Shannon, W D|Fleshman, J W|McLeod, H L
PMID: 15655543
Journal: Am J Pharmacogenomics. 2005;5(1):21-33.
Title: Pharmacogenomics of fluorouracil, irinotecan, and oxaliplatin in hepatic metastases of colorectal cancer: clinical implications.
Author: Lentz, Frederike|Tran, Agnes|Rey, Elisabeth|Pons, Gerard|Treluyer, Jean-Marc
PMID: 15727486
Journal: Expert Rev Mol Diagn. 2005 May;5(3):353-75.
Title: Molecular markers that predict response to colon cancer therapy.
Author: Ahmed, Farid E
PMID: 15934813
Journal: Clin Cancer Res. 2005 Sep 1;11(17):6212-7.
Title: ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer.
Author: Viguier, Jerome|Boige, Valerie|Miquel, Catherine|Pocard, Marc|Giraudeau, Bruno|Sabourin, Jean-Christophe|Ducreux, Michel|Sarasin, Alain|Praz, Francoise
PMID: 16144923
Journal: Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2101-8.
Title: Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.
Author: Moreno, Victor|Gemignani, Federica|Landi, Stefano|Gioia-Patricola, Lydie|Chabrier, Amelie|Blanco, Ignacio|Gonzalez, Sara|Guino, Elisabet|Capella, Gabriel|Canzian, Federico
PMID: 16609022
Journal: BMC Cancer. 2006 Jul 3;6:175.
Title: Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study.
Author: Skjelbred, Camilla F|Saebo, Mona|Nexo, Bjorn A|Wallin, Hakan|Hansteen, Inger-Lise|Vogel, Ulla|Kure, Elin H
PMID: 16817948
Journal: Int J Cancer. 2006 Nov 15;119(10):2435-42.
Title: Molecular determinants of irinotecan efficacy.
Author: Vallbohmer, Daniel|Iqbal, Syma|Yang, Dong Yun|Rhodes, Katrin E|Zhang, Wu|Gordon, Michael|Fazzone, William|Schultheis, Anne M|Sherrod, Andy E|Danenberg, Kathleen D|Lenz, Heinz-Josef
PMID: 16894565
Journal: BMC Cancer. 2006 Aug 16;6:208.
Title: Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas.
Author: Saebo, Mona|Skjelbred, Camilla Furu|Nexo, Bjorn Andersen|Wallin, Hakan|Hansteen, Inger-Lise|Vogel, Ulla|Kure, Elin H
PMID: 16914027
Journal: Oncol Rep. 2006 Nov;16(5):1085-91.
Title: The optimal schedule for 5-fluorouracil radiosensitization in colon cancer cell lines.
Author: Ojima, Eiki|Inoue, Yasuhiro|Watanabe, Hideki|Hiro, Junichiro|Toiyama, Yuji|Miki, Chikao|Kusunoki, Masato
PMID: 17016597
Journal: Adv Exp Med Biol. 2006;587:211-31.
Title: Pharmacogenomics and colorectal cancer.
Author: Lenz, Heinz-Josef
PMID: 17163168
Journal: Clin Colorectal Cancer. 2006 Nov;6(4):305-11.
Title: Gene expression levels of epidermal growth factor receptor, survivin, and vascular endothelial growth factor as molecular markers of lymph node involvement in patients with locally advanced rectal cancer.
Author: Yang, Dongyun|Schneider, Sylke|Azuma, Mizutomo|Iqbal, Syma|El-Khoueiry, Anthony|Groshen, Susan|Agafitei, Dana|Danenberg, Kathleen D|Danenberg, Peter V|Ladner, Robert D|Lenz, Heinz-Josef
PMID: 17241515
Journal: Br J Cancer. 2007 Jan 29;96(2):231-40.
Title: Mechanism of trifluorothymidine potentiation of oxaliplatin-induced cytotoxicity to colorectal cancer cells.
Author: Temmink, O H|Hoebe, E K|van der Born, K|Ackland, S P|Fukushima, M|Peters, G J
PMID: 17242697
Journal: J Clin Oncol. 2007 Apr 1;25(10):1247-54.
Title: Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy.
Author: Ruzzo, Annamaria|Graziano, Francesco|Loupakis, Fotios|Rulli, Eliana|Canestrari, Emanuele|Santini, Daniele|Catalano, Vincenzo|Ficarelli, Rita|Maltese, Paolo|Bisonni, Renato|Masi, Gianluca|Schiavon, Gaia|Giordani, Paolo|Giustini, Lucio|Falcone, Alfredo|Toni
PMID: 17401013
Journal: Oncology. 2007;72(5-6):364-70.
Title: Single nucleotide polymorphisms in nucleotide excision repair genes XPA, XPD, XPG and ERCC1 in advanced colorectal cancer patients treated with first-line oxaliplatin/fluoropyrimidine.
Author: Monzo, Mariano|Moreno, Isabel|Navarro, Alfons|Ibeas, Rafael|Artells, Rosa|Gel, Bernat|Martinez, Francisco|Moreno, Jose|Hernandez, Raquel|Navarro-Vigo, Marta
PMID: 18204222
Journal: Pharmacogenomics J. 2008 Aug;8(4):278-88.
Title: Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy.
Author: Ruzzo, A|Graziano, F|Loupakis, F|Santini, D|Catalano, V|Bisonni, R|Ficarelli, R|Fontana, A|Andreoni, F|Falcone, A|Canestrari, E|Tonini, G|Mari, D|Lippe, P|Pizzagalli, F|Schiavon, G|Alessandroni, P|Giustini, L|Maltese, P|Testa, E|Menichetti, E T|Magnani, M
PMID: 17549067
Journal: Br J Cancer. 2008 Jan 15;98(1):120-8.
Title: Cetuximab potentiates oxaliplatin cytotoxic effect through a defect in NER and DNA replication initiation.
Author: Balin-Gauthier, D|Delord, J-P|Pillaire, M-J|Rochaix, P|Hoffman, J-S|Bugat, R|Cazaux, C|Canal, P|Allal, B C
PMID: 18182978
Journal: BMC Cancer. 2008 Feb 20;8:54.
Title: A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study.
Author: Hansen, Rikke D|Sorensen, Mette|Tjonneland, Anne|Overvad, Kim|Wallin, Hakan|Raaschou-Nielsen, Ole|Vogel, Ulla
PMID: 18289367
Journal: Cancer. 2008 Jun 15;112(12):2765-73.
Title: Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer.
Author: Zheng, Zhong|Li, Xueli|Schell, Michael J|Chen, Tingan|Boulware, David|Robinson, Lary|Sommers, Eric|Bepler, Gerold
PMID: 18442042
Journal: Eur J Cancer. 2008 Jun;44(9):1229-37.
Title: Pharmacogenetic approach for capecitabine or 5-fluorouracil selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer.
Author: Martinez-Balibrea, Eva|Abad, Albert|Aranda, Enrique|Sastre, Javier|Manzano, Jose Luis|Diaz-Rubio, Eduardo|Gomez-Espana, Auxiliadora|Aparicio, Jorge|Garcia, Teresa|Maestu, Inmaculada|Martinez-Cardus, Anna|Gines, Alba|Guino, Elisabet
PMID: 18448328
Journal: Int J Oncol. 2008 Jun;32(6):1305-10.
Title: Mechanism of resistance to chemoradiation in p53 mutant human colon cancer.
Author: Hiro, Junichiro|Inoue, Yasuhiro|Toiyama, Yuji|Miki, Chikao|Kusunoki, Masato
PMID: 18497992
Journal: J Clin Oncol. 2008 Jun 1;26(16):2690-8.
Title: Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.
Author: Braun, Michael S|Richman, Susan D|Quirke, Philip|Daly, Catherine|Adlard, Julian W|Elliott, Faye|Barrett, Jennifer H|Selby, Peter|Meade, Angela M|Stephens, Richard J|Parmar, Mahesh K B|Seymour, Matthew T
PMID: 18509181
Journal: Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):650-7.
Title: Phase II study of weekly intravenous oxaliplatin combined with oral daily capecitabine and radiotherapy with biologic correlates in neoadjuvant treatment of rectal adenocarcinoma.
Author: Fakih, Marwan G|Bullarddunn, Kelli|Yang, Gary Y|Pendyala, Lakshmi|Toth, Karoly|Andrews, Chris|Rustum, Youcef M|Ross, Mary Ellen|Levea, Charles|Puthillath, Ajithkumar|Park, Young-Mee|Rajput, Ashwani
PMID: 18565686
Journal: Br J Cancer. 2008 Oct 7;99(7):1050-5.
Title: Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy.
Author: Pare, L|Marcuello, E|Altes, A|del Rio, E|Sedano, L|Salazar, J|Cortes, A|Barnadas, A|Baiget, M
PMID: 18797464
Journal: Int J Oncol. 2008 Dec;33(6):1257-62.
Title: Messenger RNA expression of TS and ERCC1 in colorectal cancer and matched liver metastasis.
Author: Kobayashi, Hirotoshi|Sugihara, Kenichi|Uetake, Hiroyuki|Higuchi, Tetsuro|Yasuno, Masamichi|Enomoto, Masayuki|Iida, Satoru|Azuma, Mizutomo|Mori, Ryutaro|Omori, Akiko|Lenz, Heinz-Josef|Danenberg, Kathleen D|Danenberg, Peter V
PMID: 19020759
Journal: BMC Cancer. 2008 Dec 23;8:386.
Title: Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine.
Author: Uchida, Kazumi|Danenberg, Peter V|Danenberg, Kathleen D|Grem, Jean L
PMID: 19105824
Journal: Carcinogenesis. 2009 Mar;30(3):472-9.
Title: Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.
Author: Joshi, Amit D|Corral, Roman|Siegmund, Kimberly D|Haile, Robert W|Le Marchand, Loic|Martinez, Maria Elena|Ahnen, Dennis J|Sandler, Robert S|Lance, Peter|Stern, Mariana C
PMID: 19029193
Journal: Int J Cancer. 2009 Mar 1;124(5):1220-6.
Title: Molecular determinants of efficacy for 5-FU-based treatments in advanced colorectal cancer: mRNA expression for 18 chemotherapy-related genes.
Author: Gustavsson, Bengt|Kaiser, Christopher|Carlsson, Goran|Wettergren, Yvonne|Odin, Elisabeth|Lindskog, Elinor Bexe|Niyikiza, Clet|Ma, Doreen
PMID: 19051292
Journal: Cancer Sci. 2009 Feb;100(2):278-83.
Title: ERCC1 codon 118 C-->T polymorphism associated with ERCC1 expression and outcome of FOLFOX-4 treatment in Asian patients with metastatic colorectal carcinoma.
Author: Chang, Peter Mu-Hsin|Tzeng, Cheng-Hwai|Chen, Po-Min|Lin, Jen-Kou|Lin, Tzu-Chen|Chen, Wei-Shone|Jiang, Jeng-Kae|Wang, Huann-Sheng|Wang, Wei-Shu
PMID: 19068092
Journal: Am J Clin Oncol. 2009 Feb;32(1):38-43.
Title: Prognostic value of ERCC1, thymidylate synthase, and glutathione S-transferase pi for 5-FU/oxaliplatin chemotherapy in advanced colorectal cancer.
Author: Kim, Sung-Hyun|Kwon, Hyuk-Chan|Oh, Sung Yong|Lee, Dong Mee|Lee, Suee|Lee, Jong-Hoon|Roh, Mee-Sook|Kim, Dae-Cheol|Park, Ki-Jae|Choi, Hong-Jo|Kim, Hyo-Jin
PMID: 19194123
Journal: Hum Pathol. 2009 May;40(5):639-44.
Title: Prognostic value of aspartyl (asparaginyl)-beta-hydroxylase/humbug expression in non-small cell lung carcinoma.
Author: Luu, Martin|Sabo, Edmond|de la Monte, Suzanne M|Greaves, Wesley|Wang, JiYi|Tavares, Rosemarie|Simao, Lelia|Wands, Jack R|Resnick, Murray B|Wang, LiJuan
PMID: 19200576
Journal: Int J Cancer. 2009 Jun 15;124(12):2997-3001.
Title: Functional evidence for Eme1 as a marker of cisplatin resistance.
Author: Tomoda, Yoshitaka|Katsura, Mari|Okajima, Miyuki|Hosoya, Noriko|Kohno, Nobuoki|Miyagawa, Kiyoshi
PMID: 19267403
Journal: Best Pract Res Clin Gastroenterol. 2009;23(2):257-73.
Title: Pharmacogenetics in chemotherapy of colorectal cancer.
Author: Henriette Tanja, Lieke|Guchelaar, Henk-Jan|Gelderblom, Hans
PMID: 19414151
Journal: Eur J Cancer. 2009 Jul;45(11):1999-2006.
Title: Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study.
Author: Koopman, Miriam|Venderbosch, Sabine|van Tinteren, Harm|Ligtenberg, Marjolijn J|Nagtegaal, Iris|Van Krieken, Johan H|Punt, Cornelis J
PMID: 19457654
Journal: JOP. 2009 Jul 6;10(4):357-60.
Title: Pharmacogenetics in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009.
Author: Strimpakos, Alexios S|Syrigos, Kostas N|Saif, Muhammad Wasif
PMID: 19581734
Journal: Cancer Biol Ther. 2009 Oct;8(20):1914-21. Epub 2009 Oct 6.
Title: The overexpression of ERCC-1 is involved in the resistance of lung cancer cells to cetuximab combined with DDP.
Author: Li, Jing-Jing|Ding, Ya|Li, Dan-Dan|Peng, Rui-Qing|Feng, Gong-Kan|Zeng, Yi-Xin|Zhu, Xiao-Feng|Zhang, Xiao-Shi
PMID: 20009541
Journal: Ecancermedicalscience. 2009;3:153.
Title: Oxaliplatin: pre-clinical perspectives on the mechanisms of action, response and resistance.
Author: Seetharam, Rn|Sood, A|Goel, S
PMID: 22276017
Journal: Cancer Sci. 2010 Feb;101(2):530-5.
Title: Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma.
Author: Chen, Yen-Chung|Tzeng, Cheng-Hwai|Chen, Po-Min|Lin, Jen-Kou|Lin, Tzu-Chen|Chen, Wei-Shone|Jiang, Jeng-Kae|Wang, Huann-Sheng|Wang, Wei-Shu
PMID: 19922504
Journal: Int J Cancer. 2010 Sep 1;127(5):1028-37.
Title: Evidence of heterogeneity within colorectal liver metastases for allelic losses, mRNA level expression and in vitro response to chemotherapeutic agents.
Author: Goasguen, Nicolas|de Chaisemartin, Cecile|Brouquet, Antoine|Julie, Catherine|Prevost, Gregoire P|Laurent-Puig, Pierre|Penna, Christophe
PMID: 20017140
Journal: Cancer Chemother Pharmacol. 2010 Aug;66(3):547-58.
Title: Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines.
Author: Nannizzi, Sara|Veal, Gareth J|Giovannetti, Elisa|Mey, Valentina|Ricciardi, Simona|Ottley, Christopher J|Del Tacca, Mario|Danesi, Romano
PMID: 20020129
Journal: Br J Clin Pharmacol. 2010 Jan;69(1):58-66.
Title: Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and FOLFOX response in colorectal cancer patients.
Author: Etienne-Grimaldi, Marie-Christine|Milano, Gerard|Maindrault-Goebel, Frederique|Chibaudel, Benoist|Formento, Jean-Louis|Francoual, Mireille|Lledo, Gerard|Andre, Thierry|Mabro, May|Mineur, Laurent|Flesch, Michel|Carola, Elisabeth|de Gramont, Aimery
PMID: 20078613
Journal: Int J Mol Med. 2010 Mar;25(3):321-9.
Title: Expression profile of significant immortalization genes in colon cancer.
Author: Witkowska, Agnieszka|Gumprecht, Janusz|Glogowska-Ligus, Joanna|Wystrychowski, Grzegorz|Owczarek, Aleksander|Stachowicz, Malgorzata|Bocianowska, Alina|Nowakowska-Zajdel, Ewa|Mazurek, Urszula
PMID: 20127035
Journal: Pharmacogenomics. 2010 Jun;11(6):747-61.
Title: Pharmacogenetic analysis in neoadjuvant chemoradiation for rectal cancer: high incidence of somatic mutations and their relation with response.
Author: Balboa, Emilia|Duran, Goretti|Lamas, Maria Jesus|Gomez-Caamano, Antonio|Celeiro-Munoz, Catuxa|Lopez, Rafael|Carracedo, Angel|Barros, Francisco
PMID: 20504250
Journal: Anticancer Res. 2010 Jul;30(7):2531-8.
Title: Oxaliplatin resistance induced by ERCC1 up-regulation is abrogated by siRNA-mediated gene silencing in human colorectal cancer cells.
Author: Seetharam, Raviraja N|Sood, Arjun|Basu-Mallick, Atrayee|Augenlicht, Leonard H|Mariadason, John M|Goel, Sanjay
PMID: 20682979
Journal: J Vis Exp. 2010 Jul 28;(41). pii: 1931.
Title: Deficient Pms2, ERCC1, Ku86, CcOI in field defects during progression to colon cancer.
Author: Nguyen, Huy|Loustaunau, Cristy|Facista, Alexander|Ramsey, Lois|Hassounah, Nadia|Taylor, Hilary|Krouse, Robert|Payne, Claire M|Tsikitis, V Liana|Goldschmid, Steve|Banerjee, Bhaskar|Perini, Rafael F|Bernstein, Carol
PMID: 20689513
Journal: Int J Clin Pharmacol Ther. 2010 Nov;48(11):729-34.
Title: Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genes.
Author: Inada, M|Sato, M|Morita, S|Kitagawa, K|Kawada, K|Mitsuma, A|Sawaki, M|Fujita, K|Ando, Y
PMID: 20979931
Journal: Exp Ther Med. 2010 Mar;1(2):331-336.
Title: Gene expression and effects of orally active derivatives of fluoropyrimidine on gastric and colorectal cancer.
Author: Arakawa, Satoshi|Ozawa, Soji|Kawase, Jin|Oshima, Hisanori|Nagata, Hidetoshi|Atsuta, Koji|Umemoto, Shunji
PMID: 22993546
Journal: Pharmacogenomics J. 2011 Jun;11(3):214-26.
Title: Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.
Author: Cecchin, E|Agostini, M|Pucciarelli, S|De Paoli, A|Canzonieri, V|Sigon, R|De Mattia, E|Friso, M L|Biason, P|Visentin, M|Nitti, D|Toffoli, G
PMID: 20368715
Journal: Clin Cancer Res. 2011 Mar 15;17(6):1632-40.
Title: ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis.
Author: Yin, Ming|Yan, Jingrong|Martinez-Balibrea, Eva|Graziano, Francesco|Lenz, Heinz-Josef|Kim, Hyo-Jin|Robert, Jacques|Im, Seock-Ah|Wang, Wei-Shu|Etienne-Grimaldi, Marie-Christine|Wei, Qingyi
PMID: 21278243
Journal: Clin Cancer Res. 2011 May 15;17(10):3469-77.
Title: Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Author: Grimminger, Peter P|Danenberg, Peter|Dellas, Kathrin|Arnold, Dirk|Rodel, Claus|Machiels, Jean-Pascal|Haustermans, Karin|Debucquoy, Annelies|Velenik, Vaneja|Sempoux, Christine|Bracko, Matej|Holscher, Arnulf H|Semrau, Robert|Yang, Dongyun|Danenberg, Kathlee
PMID: 21558395
Journal: Curr Drug Metab. 2011 Dec;12(10):918-31.
Title: Pharmacokinetic and metabolism determinants of fluoropyrimidines and oxaliplatin activity in treatment of colorectal patients.
Author: Gnoni, Antonio|Russo, Antonio|Silvestris, Nicola|Maiello, Evaristo|Vacca, Angelo|Marech, Ilaria|Numico, Gianmauro|Paradiso, Angelo|Lorusso, Vito|Azzariti, Amalia
PMID: 21787270
Journal: Clin Colorectal Cancer. 2011 Sep;10(3):157-64.
Title: A review of excision repair cross-complementation group 1 in colorectal cancer.
Author: Bohanes, Pierre|Labonte, Melissa J|Lenz, Heinz-Josef
PMID: 21855036
Journal: Anticancer Res. 2011 Sep;31(9):2763-71.
Title: Prognostic significance of thymidylate synthase expression in the adjuvant chemotherapy after resection for pulmonary metastases from colorectal cancer.
Author: Kaira, Kyoichi|Okumura, Takehiro|Ohde, Yasuhisa|Takahashi, Toshiaki|Murakami, Haruyasu|Kondo, Haruhiko|Nakajima, Takashi|Yamamoto, Nobuyuki
PMID: 21868518
Journal: Mol Diagn Ther. 2011 Oct 1;15(5):277-83.
Title: Pharmacogenetics of oxaliplatin as adjuvant treatment in colon carcinoma: are single nucleotide polymorphisms in GSTP1, ERCC1, and ERCC2 good predictive markers?
Author: Farina Sarasqueta, Arantza|van Lijnschoten, Gesina|Lemmens, Valery E P P|Rutten, Harm J T|van den Brule, Adriaan J C
PMID: 21958378
Journal: Anticancer Res. 2011 Nov;31(11):3843-9.
Title: Relationship between TYMS and ERCC1 mRNA expression and in vitro chemosensitivity in colorectal cancer.
Author: Cho, Yong Beom|Chung, Hyuk Jun|Lee, Woo Yong|Choi, Sung Ho|Kim, Hee Cheol|Yun, Seong Hyeon|Chun, Ho-Kyung
PMID: 22110208
Journal: Gan To Kagaku Ryoho. 2011 Nov;38(12):2220-3.
Title: [Prediction of the efficacy of modified FOLFOX6 therapy according to the mRNA levels of thymidylate synthase (TS), excision repair cross-complementing-1 and -2( ERCC-1 and ERCC-2) and methylenetetrahydrofolate dehydrogenase( MTHFD) in the primary lesion o
Author: Ishibashi, Keiichiro|Okada, Norimichi|Tajima, Yusuke|Ishiguro, Toru|Kuwabara, Kouki|Ohsawa, Tomonori|Kumamoto, Kensuke|Tsuji, Yoshitaka|Haga, Norihiro|Iwama, Takeo|Ishida, Hideyuki|Onouchi, Tsuneko|Yakabi, Koji
PMID: 22202336
Journal: Gan To Kagaku Ryoho. 2011 Nov;38(12):2224-7.
Title: [The Relationship between the efficacy of mFOLFOX6 treatment and the expression of TS, DPD, TP, and ERCC-1 in unresectable colorectal cancer].
Author: Kuwabara, Kouki|Kumamoto, Kensuke|Ishibashi, Keiichiro|Okada, Norimichi|Ishiguro, Toru|Ohsawa, Tomonori|Haga, Norihiro|Miura, Ichiro|Ishida, Hideyuki
PMID: 22202337
Journal: Nihon Rinsho. 2011 Apr;69 Suppl 3:494-9.
Title: [Predictive marker for the efficacy of FOLFOX treatment in colon cancer (TS, ERCC1 etc)].
Author: Kumamoto, Kensuke|Ishibashi, Keiichiro|Ishida, Hideyuki
PMID: 22214010
Journal: Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):138-44.
Title: X-ray cross-complementing group 1 and thymidylate synthase polymorphisms might predict response to chemoradiotherapy in rectal cancer patients.
Author: Lamas, Maria J|Duran, Goretti|Gomez, Antonio|Balboa, Emilia|Anido, Urbano|Bernardez, Beatriz|Rana-Diez, Pablo|Lopez, Rafael|Carracedo, Angel|Barros, Francisco
PMID: 21167658
Journal: Mol Biol Rep. 2012 Jan;39(1):527-34.
Title: The C/A polymorphism in intron 11 of the XPC gene plays a crucial role in the modulation of an individual's susceptibility to sporadic colorectal cancer.
Author: Gil, Justyna|Ramsey, Dave|Stembalska, Agnieszka|Karpinski, Pawel|Pesz, Karolina A|Laczmanska, Izabela|Leszczynski, Przemyslaw|Grzebieniak, Zygmunt|Sasiadek, Maria Malgorzata
PMID: 21559836
Journal: Hepatogastroenterology. 2012 Jan-Feb;59(113):130-3.
Title: Predictive value of expression of ERCC 1 and GST-p for 5-fluorouracil/oxaliplatin chemotherapy in advanced colorectal cancer.
Author: Noda, Eiji|Maeda, Kiyoshi|Inoue, Toru|Fukunaga, Shinya|Nagahara, Hisashi|Shibutani, Masatsune|Amano, Ryosuke|Nakata, Bunzo|Tanaka, Hiroaki|Muguruma, Kazuya|Yamada, Nobuya|Yashiro, Masakazu|Ohira, Masaichi|Ishikawa, Tetsuro|Hirakawa, Kosei
PMID: 21940361
Journal: Cancer. 2012 Aug 15;118(16):3882-92.
Title: Exploring biomarkers in head and neck cancer.
Author: Langer, Corey J
PMID: 22281752
Journal: Genome Integr. 2012 Apr 11;3(1):3.
Title: Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer.
Author: Facista, Alexander|Nguyen, Huy|Lewis, Cristy|Prasad, Anil R|Ramsey, Lois|Zaitlin, Beryl|Nfonsam, Valentine|Krouse, Robert S|Bernstein, Harris|Payne, Claire M|Stern, Stephen|Oatman, Nicole|Banerjee, Bhaskar|Bernstein, Carol
PMID: 22494821
Journal: Int J Clin Exp Med. 2012;5(2):186-94. Epub 2012 Apr 6.
Title: ERCC1 C118T associates with response to FOLFOX4 chemotherapy in colorectal cancer patients in Han Chinese.
Author: Chai, Haina|Pan, Jie|Zhang, Xuelin|Zhang, Xiaoyan|Shen, Xiaoying|Li, Hang|Zhang, Kehao|Yang, Changqing|Sheng, Haihui|Gao, Hengjun
PMID: 22567180
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 May;32(5):628-32.
Title: [Study of the correlation between the colorectal cancer Chinese medicine syndrome types and (excision repair cross-complementing 1, ERCC1) gene polymorphisms].
Author: Cui, Tong-Jian|Chen, Yi-Qian|Dai, Yong-Mei
PMID: 22679723
Journal: Oncol Lett. 2012 May;3(5):983-989.
Title: Thymidylate synthase and thymidine phosphorylase mRNA expression in primary lesions using laser capture microdissection is useful for prediction of the efficacy of FOLFOX treatment in colorectal cancer patients with liver metastasis.
Author: Kumamoto, Kensuke|Kuwabara, Koki|Tajima, Yusuke|Amano, Kunihiko|Hatano, Satoshi|Ohsawa, Tomonori|Okada, Norimichi|Ishibashi, Keiichiro|Haga, Norihiro|Ishida, Hideyuki
PMID: 22783377
Journal: Pharmacogenomics. 2012 Jul;13(10):1173-91.
Title: Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients.
Author: Cortejoso, Lucia|Lopez-Fernandez, Luis A
PMID: 22909207
Journal: Clin Transl Oncol. 2012 Sep;14(9):641-58.
Title: Management of colorectal cancer patients after resection of liver metastases: can we offer a tailored treatment?
Author: Lopez-Gomez, Miriam|Cejas, Paloma|Merino, Maria|Fernandez-Luengas, David|Casado, Enrique|Feliu, Jaime
PMID: 22911546
Journal: Asian Pac J Cancer Prev. 2012;13(7):3465-9.
Title: GSTP1, ERCC1 and ERCC2 polymorphisms, expression and clinical outcome of oxaliplatin-based adjuvant chemotherapy in colorectal cancer in Chinese population.
Author: Li, Hui-Yan|Ge, Xin|Huang, Guang-Ming|Li, Kai-Yu|Zhao, Jing-Quan|Yu, Xi-Miao|Bi, Wen-Si|Wang, Yu-Lin
PMID: 22994779
Journal: PLoS One. 2012;7(11):e50701.
Title: KRAS mutation is a predictor of oxaliplatin sensitivity in colon cancer cells.
Author: Lin, Yu-Lin|Liau, Jau-Yu|Yu, Shan-Chi|Ou, Da-Liang|Lin, Liang-In|Tseng, Li-Hui|Chang, Yih-Leong|Yeh, Kun-Huei|Cheng, Ann-Lii
PMID: 23209813
Journal: PLoS One. 2012;7(12):e51329.
Title: Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction.
Author: Barakat, Khaled H|Jordheim, Lars P|Perez-Pineiro, Rolando|Wishart, David|Dumontet, Charles|Tuszynski, Jack A
PMID: 23272099
Journal: J Clin Lab Anal. 2012 Jan;26(1):10-5.
Title: ERCC1 and XPD/ERCC2 polymorphisms' predictive value of oxaliplatin-based chemotherapies in advanced colorectal cancer has an ethnic discrepancy: a meta-analysis.
Author: Lu, Xiaobo|Xiao, Sha|Jin, Cuihong|van der Straaten, Tahar|Li, Xiaoxia
PMID: 24833529
Journal: Br J Cancer. 2013 Jan 15;108(1):115-20.
Title: KRAS mutational status affects oxaliplatin-based chemotherapy independently from basal mRNA ERCC-1 expression in metastatic colorectal cancer patients.
Author: Basso, M|Strippoli, A|Orlandi, A|Martini, M|Calegari, M A|Schinzari, G|Di Salvatore, M|Cenci, T|Cassano, A|Larocca, L M|Barone, C
PMID: 23175150
Journal: J Cancer Res Clin Oncol. 2013 Mar;139(3):465-73.
Title: PPP1R13L variant associated with prognosis for patients with rectal cancer.
Author: Chae, Yee Soo|Kim, Jong Gwang|Kang, Byung Woog|Lee, Soo Jung|Jeon, Hyo-Sung|Park, Jun Seok|Choi, Gyu Seog|Lee, Won Kee
PMID: 23180017
Journal: Cancer Chemother Pharmacol. 2013 Apr;71(4):843-51.
Title: Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer.
Author: Lee, Kyung-Hun|Chang, Hye Jung|Han, Sae-Won|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Kim, Sun Young|Lee, Keun-Wook|Kim, Jee Hyun|Hong, Yong Sang|Kim, Tae Won|Park, Young Suk|Kang, Won Ki|Shin, Sang Joon|Ahn, Joong Bae|Kang, Gyeong Hoon|Jeong, Seung-Yong|Pa
PMID: 23314736
Journal: Clin Colorectal Cancer. 2013 Jun;12(2):122-7.
Title: Role of conventional chemosensitivity test and tissue biomarker expression in predicting response to treatment of peritoneal carcinomatosis from colon cancer.
Author: Arienti, Chiara|Tesei, Anna|Verdecchia, Giorgio Maria|Framarini, Massimo|Virzi, Salvatore|Grassi, Antonio|Scarpi, Emanuela|Turci, Livia|Silvestrini, Rosella|Amadori, Dino|Zoli, Wainer
PMID: 23332421
Journal: Anticancer Drugs. 2013 Apr;24(4):355-65.
Title: Induction of apoptosis and suppression of ERCC1 expression by the potent amonafide analogue 8-c in human colorectal carcinoma cells.
Author: Wang, Ziyuan|Liang, Xin|Cheng, Zhuoan|Xu, Yufang|Yin, Peihao|Zhu, Huirong|Li, Qi|Qian, Xuhong|Liu, Jianwen
PMID: 23426174
Journal: Int J Mol Sci. 2013 Feb 19;14(2):4121-34.
Title: Polymorphisms in XPD and ERCC1 Associated with Colorectal Cancer Outcome.
Author: Huang, Ming-Yii|Wang, Jaw-Yuan|Huang, Meng-Lin|Chang, Hui-Jen|Lin, Shiu-Ru
PMID: 23429196
Journal: Br J Cancer. 2013 Apr 2;108(6):1238-44.
Title: ERCC1, defective mismatch repair status as predictive biomarkers of survival for stage III colon cancer patients receiving oxaliplatin-based adjuvant chemotherapy.
Author: Li, P|Fang, Y J|Li, F|Ou, Q J|Chen, G|Ma, G
PMID: 23481186
Journal: BMC Cancer. 2013 Mar 6;13:103.
Title: BRCA1 and ERCC1 mRNA levels are associated with lymph node metastasis in Chinese patients with colorectal cancer.
Author: Yuanming, Lu|Lineng, Zhang|Baorong, Song|Junjie, Peng|Sanjun, Cai
PMID: 23496813
Journal: Cancer Chemother Pharmacol. 2013 Jun;71(6):1463-72.
Title: Differential toxicity biomarkers for irinotecan- and oxaliplatin-containing chemotherapy in colorectal cancer.
Author: Cortejoso, Lucia|Garcia, Maria I|Garcia-Alfonso, Pilar|Gonzalez-Haba, Eva|Escolar, Fernando|Sanjurjo, Maria|Lopez-Fernandez, Luis A
PMID: 23543295
Journal: Int J Clin Pharmacol Ther. 2013 Jun;51(6):475-81.
Title: Genetic polymorphisms associated with oxaliplatin-induced peripheral neurotoxicity in Japanese patients with colorectal cancer.
Author: Oguri, Tomoyo|Mitsuma, Ayako|Inada-Inoue, Megumi|Morita, Sachi|Shibata, Takashi|Shimokata, Tomoya|Sugishita, Mihoko|Nakayama, Goro|Uehara, Keisuke|Hasegawa, Yoshinori|Ando, Yuichi
PMID: 23547850
Journal: J Oncol. 2013;2013:386906.
Title: Analysis of the mRNA expression of chemotherapy-related genes in colorectal carcinoma using the danenberg tumor profile method.
Author: Sasaki, Shin|Watanabe, Toshiyuki|Nakayama, Hiroshi
PMID: 23577026
Journal: Cancer Chemother Pharmacol. 2013 Jul;72(1):117-25.
Title: MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.
Author: Tentori, Lucio|Muzi, Alessia|Dorio, Annalisa Susanna|Dolci, Susanna|Campolo, Federica|Vernole, Patrizia|Lacal, Pedro Miguel|Praz, Francoise|Graziani, Grazia
PMID: 23636450
Journal: J Natl Cancer Inst. 2013 Jul 3;105(13):937-46.
Title: MyD88 in DNA repair and cancer cell resistance to genotoxic drugs.
Author: Kfoury, Alain|Le Corf, Katy|El Sabeh, Rana|Journeaux, Alexandra|Badran, Bassam|Hussein, Nader|Lebecque, Serge|Manie, Serge|Renno, Toufic|Coste, Isabelle
PMID: 23766530
Journal: J Surg Oncol. 2013 Dec;108(7):457-64.
Title: Predictive value of ERCC1, ERCC2, and XRCC1 overexpression for stage III colorectal cancer patients receiving FOLFOX-4 adjuvant chemotherapy.
Author: Huang, Ming-Yii|Tsai, Hsiang-Lin|Lin, Chih-Hung|Huang, Ching-Wen|Ma, Cheng-Jen|Huang, Chun-Ming|Chai, Chee-Yin|Wang, Jaw-Yuan
PMID: 23996617
Journal: Oncology (Williston Park). 2013 Aug;27(8):746-54.
Title: Use of molecular biomarkers to inform adjuvant therapy for colon cancer.
Author: Mettu, Niharika B|Hurwitz, Herbert|Hsu, David S
PMID: 24133820
Journal: Oncol Lett. 2013 Sep;6(3):648-654.
Title: Polymorphisms of GSTP1, ERCC2 and TS-3'UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients.
Author: Kumamoto, Kensuke|Ishibashi, Keiichiro|Okada, Norimichi|Tajima, Yusuke|Kuwabara, Kouki|Kumagai, Yoichi|Baba, Hiroyuki|Haga, Norihiro|Ishida, Hideyuki
PMID: 24137384
Journal: BMC Cancer. 2013 Oct 21;13:489.
Title: An explorative analysis of ERCC1-19q13 copy number aberrations in a chemonaive stage III colorectal cancer cohort.
Author: Smith, David Hersi|Christensen, Ib Jarle|Jensen, Niels Frank|Markussen, Bo|Muller, Sven|Nielsen, Hans Jorgen|Brunner, Nils|Nielsen, Kirsten Vang
PMID: 24144331
Journal: J Natl Compr Canc Netw. 2013 Sep;11 Suppl 4:S9-17.
Title: Multigene assays in metastatic colorectal cancer.
Author: Deeb, Kristin K|Sram, Jakub P|Gao, Hanlin|Fakih, Marwan G
PMID: 24158971
Journal: Zhonghua Yi Xue Za Zhi. 2013 Dec 24;93(48):3852-6.
Title: [Clinical values of detecting excision repair cross complementing 1 and top-isomerase I in individualized therapies of metastatic colorectal cancer].
Author: Qiu, Ji-gang|Shen, Da-ming|Huang, Chun-jin|Tang, Jian-xiong
PMID: 24548447
Journal: Mutat Res. 2014 Jan;759:37-44.
Title: Excision Repair Cross-Complementation group 1 (ERCC1) C118T SNP does not affect cellular response to oxaliplatin.
Author: van Huis-Tanja, Lieke H|Kweekel, Dina M|Lu, Xiaobo|Franken, Kees|Koopman, Miriam|Gelderblom, Hans|Antonini, Ninja F|Punt, Cornelis J A|Guchelaar, Henk-Jan|van der Straaten, Tahar
PMID: 24220697
Journal: Mol Med Rep. 2014 Feb;9(2):669-76.
Title: Cinnamaldehyde/chemotherapeutic agents interaction and drug-metabolizing genes in colorectal cancer.
Author: Yu, Chen|Liu, Shen-Lin|Qi, Ming-Hao|Zou, Xi
PMID: 24276478
Journal: Cancer Res Treat. 2014 Jan;46(1):55-64.
Title: Combination of TRAP1 and ERCC1 Expression Predicts Clinical Outcomes in Metastatic Colorectal Cancer Treated with Oxaliplatin/5-Fluorouracil.
Author: Han, Jae Joon|Baek, Sun Kyung|Lee, Jae Jin|Kim, Gou Young|Kim, Si-Young|Lee, Suk-Hwan
PMID: 24520224
Journal: Sci Rep. 2014 Feb 17;4:4112.
Title: Association of ERCC1 and ERCC2 polymorphisms with colorectal cancer risk in a Chinese population.
Author: Ni, Min|Zhang, Wei-zhong|Qiu, Jin-rong|Liu, Fei|Li, Min|Zhang, Ya-jie|Liu, Qing|Bai, Jin
PMID: 24531312
Journal: Sci Rep. 2014 Mar 7;4:4313.
Title: Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody.
Author: Smith, David Hersi|Fiehn, Anne-Marie Kanstrup|Fogh, Louise|Christensen, Ib Jarle|Hansen, Tine Plato|Stenvang, Jan|Nielsen, Hans Jorgen|Nielsen, Kirsten Vang|Hasselby, Jane Preuss|Brunner, Nils|Jensen, Sussie Steen
PMID: 24603753
Journal: J Cancer. 2014 May 2;5(6):425-32.
Title: ERCC1, XRCC1 and GSTP1 Single Nucleotide Polymorphisms and Survival of Patients with Colon Cancer Receiving Oxaliplatin-Based Adjuvant Chemotherapy.
Author: Zaanan, Aziz|Dalban, Cecile|Emile, Jean-Francois|Blons, Helene|Flejou, Jean-Francois|Goumard, Claire|Istanbullu, Melek|Calmel, Claire|Alhazmi, Khalid|Validire, Pierre|Louvet, Christophe|de Gramont, Aimery|Laurent-Puig, Pierre|Taieb, Julien|Praz, Francoise
PMID: 24847383
Journal: Gene. 2014 Sep 10;548(1):1-5.
Title: Association of single nucleotide polymorphisms of ERCC1 and XPF with colorectal cancer risk and interaction with tobacco use.
Author: Hou, Ruizhi|Liu, Yan|Feng, Ye|Sun, Libo|Shu, Zhenbo|Zhao, Jisheng|Yang, Shujuan
PMID: 24861646
Journal: Med Oncol. 2014 Jul;31(7):72.
Title: CYP1A1 Ile462Val polymorphism and colorectal cancer risk in Polish patients.
Author: Gil, Justyna|Gaj, Pawel|Misiak, Blazej|Ostrowski, Jerzy|Karpinski, Pawel|Jarczynska, Alicja|Kielan, Wojciech|Sasiadek, Maria Malgorzata
PMID: 24939416
Journal: World J Gastrointest Oncol. 2014 Jul 15;6(7):225-43.
Title: Novel diet-related mouse model of colon cancer parallels human colon cancer.
Author: Prasad, Anil R|Prasad, Shilpa|Nguyen, Huy|Facista, Alexander|Lewis, Cristy|Zaitlin, Beryl|Bernstein, Harris|Bernstein, Carol
PMID: 25024814
Journal: Farm Hosp. 2014 Jul 1;38(4):283-90.
Title: [Validation of genetic polymorphisms associated to the toxicity of chemotherapy in colorectal cancer patients].
Author: Cortejoso, L|Garcia, M I|Garcia-Alfonso, P|Gravalos, C|Robles, L|Gonzalez-Haba, E|Sanjurjo, M|Lopez-Fernandez, L A
PMID: 25137161
Journal: BMC Gastroenterol. 2014 Aug 29;14:154.
Title: Association between ERCC1 and TS mRNA levels and disease free survival in colorectal cancer patients receiving oxaliplatin and fluorouracil (5-FU) adjuvant chemotherapy.
Author: Li, Sheng|Zhu, Liangjun|Yao, Li|Xia, Lei|Pan, Liangxi
PMID: 25175730
Journal: Onco Targets Ther. 2014 Oct 4;7:1817-28.
Title: Colorectal cancer in Chinese patients: current and emerging treatment options.
Author: Li, Leung|Ma, Brigette By
PMID: 25336973
Journal: Asian Pac J Cancer Prev. 2014;15(19):8383-90.
Title: The ERCC1 C118T polymorphism predicts clinical outcomes of colorectal cancer patients receiving oxaliplatin-based chemotherapy: a meta-analysis based on 22 studies.
Author: Qian, Ying-Ying|Liu, Xin-You|Wu, Qian|Song, Xian|Chen, Xiao-Feng|Liu, Yi-Qian|Pei, Dong|Shen, Li-Zong|Shu, Yong-Qian
PMID: 25339033
Journal: Sci Rep. 2014 Nov 5;4:6828.
Title: Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients.
Author: Ruzzo, Annamaria|Graziano, Francesco|Galli, Fabio|Giacomini, Elisa|Floriani, Irene|Galli, Francesca|Rulli, Eliana|Lonardi, Sara|Ronzoni, Monica|Massidda, Bruno|Zagonel, Vittorina|Pella, Nicoletta|Mucciarini, Claudia|Labianca, Roberto|Ionta, Maria Teresa|V
PMID: 25370899
Journal: Pharmacogenomics J. 2015 Feb;15(1):77-83.
Title: EGFR ligands and DNA repair genes: genomic predictors of complete response after capecitabine-based chemoradiotherapy in locally advanced rectal cancer.
Author: Sebio, A|Salazar, J|Paez, D|Berenguer-Llergo, A|Del Rio, E|Tobena, M|Martin-Richard, M|Sullivan, I|Targarona, E|Balart, J|Baiget, M|Barnadas, A
PMID: 25026457
Journal: Clin Transl Oncol. 2015 Apr;17(4):322-9.
Title: Gene expression differences in primary colorectal tumors and matched liver metastases: chemotherapy related or tumoral heterogeneity?
Author: Lopez-Gomez, M|Moreno-Rubio, J|Suarez-Garcia, I|Cejas, P|Madero, R|Casado, E|Jimenez, A M|Sereno, M|Gomez-Raposo, C|Zambrana, F|Merino, M|Fernandez-Luengas, D|Feliu, J
PMID: 25301403
Journal: Exp Mol Pathol. 2015 Jun;98(3):375-81.
Title: Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR.
Author: Wang, Huijuan|Yang, Bobo|Geng, Tingting|Li, Bin|Dai, Penggao|Chen, Chao
PMID: 25445497
Journal: Pharmacogenomics J. 2015 Aug;15(4):354-62.
Title: Distinct gene expression profiles of proximal and distal colorectal cancer: implications for cytotoxic and targeted therapy.
Author: Maus, M K H|Hanna, D L|Stephens, C L|Astrow, S H|Yang, D|Grimminger, P P|Loupakis, F|Hsiang, J H|Zeger, G|Wakatsuki, T|Barzi, A|Lenz, H-J
PMID: 25532759
Journal: J Cancer. 2015 Jan 1;6(1):70-81.
Title: ERCC1 Induction after Oxaliplatin Exposure May Depend on KRAS Mutational Status in Colorectal Cancer Cell Line: In Vitro Veritas.
Author: Orlandi, A|Di Salvatore, M|Bagala, C|Basso, M|Strippoli, A|Plastino, F|Calegari, M A|Cassano, A|Astone, A|Barone, C
PMID: 25553091
Journal: Clin Cancer Res. 2015 Apr 1;21(7):1583-90.
Title: Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation.
Author: Bohanes, Pierre|Rankin, Cathryn J|Blanke, Charles D|Winder, Thomas|Ulrich, Cornelia M|Smalley, Stephen R|Rich, Tyvin A|Martensen, James A|Benson, Al B 3rd|Mayer, Robert J|Cripps, Christine M|Danenberg, Kathleen|Makar, Karen W|Zhang, Wu|Benedetti, Jacqueli
PMID: 25589620
Journal: Cancer Chemother Pharmacol. 2015 Apr;75(4):763-72.
Title: Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy.
Author: Joerger, M|Huitema, A D R|Boot, H|Cats, A|Doodeman, V D|Smits, P H M|Vainchtein, L|Rosing, H|Meijerman, I|Zueger, M|Meulendijks, D|Cerny, T D|Beijnen, J H|Schellens, J H M
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Journal: Asian Pac J Cancer Prev. 2015;16(2):713-8.
Title: DNA repair gene polymorphisms do not predict response to radiotherapy-based multimodality treatment of patients with rectal cancer: a meta-analysis.
Author: Guo, Cheng-Xian|Yang, Guo-Ping|Pei, Qi|Yin, Ji-Ye|Tan, Hong-Yi|Yuan, Hong
PMID: 25684513
Journal: Mutagenesis. 2015 May;30(3):441-9.
Title: XRCC1 and ERCC1 polymorphisms are related to susceptibility and survival of colorectal cancer in the Chinese population.
Author: Dai, Qiong|Luo, Hua|Li, Xing Pu|Huang, Juan|Zhou, Tie Jun|Yang, Zhi-Hui
PMID: 25690281
Journal: Genet Mol Res. 2015 Jan 30;14(1):700-5.
Title: Association between ERCC1 and XPF polymorphisms and risk of colorectal cancer.
Author: Yang, H|Li, G|Li, W F
PMID: 25730007
Journal: Onco Targets Ther. 2015 Mar 16;8:641-8.
Title: Association between the ERCC1 rs11615 polymorphism and clinical outcomes of oxaliplatin-based chemotherapies in gastrointestinal cancer: a meta-analysis.
Author: Ma, Shou-Cheng|Zhao, Yue|Zhang, Tao|Ling, Xiao-Ling|Zhao, Da
PMID: 25834456
Journal: Ann Coloproctol. 2015 Jun;31(3):81.
Title: ERCC1 and the Prognosis for Patients With Colon Cancer Receiving Oxaliplatin-Based Adjuvant Chemotherapy.
Author: Baek, Moo-Jun
PMID: 26161372
Journal: Ann Coloproctol. 2015 Jun;31(3):92-7.
Title: ERCC1 as a Predictive Marker for FOLFOX Chemotherapy in an Adjuvant Setting.
Author: Kim, Chee Young|Seo, Sang Hyuk|An, Min Sung|Kim, Kwang Hee|Bae, Ki Beom|Hwang, Jin Won|Kim, Ji Hyun|Kim, Bo Mi|Kang, Mi Seon|Oh, Min Kyung|Hong, Kwan Hee
PMID: 26161376
Journal: Oncotarget. 2015 Oct 20;6(32):34004-13.
Title: Changes in expression levels of ERCC1, DPYD, and VEGFA mRNA after first-line chemotherapy of metastatic colorectal cancer: results of a multicenter study.
Author: Baba, Hideo|Baba, Yoshifumi|Uemoto, Shinji|Yoshida, Kazuhiro|Saiura, Akio|Watanabe, Masayuki|Maehara, Yoshihiko|Oki, Eiji|Ikeda, Yasuharu|Matsuda, Hiroyuki|Yamamoto, Masakazu|Shimada, Mitsuo|Taketomi, Akinobu|Unno, Michiaki|Sugihara, Kenichi|Ogata, Yutaka
PMID: 26372896
Journal: Am J Clin Oncol. 2016 Jun;39(3):236-42.
Title: Phase II Trial of Target-guided Personalized Chemotherapy in First-line Metastatic Colorectal Cancer.
Author: Cubillo, Antonio|Rodriguez-Pascual, Jesus|Lopez-Rios, Fernando|Plaza, Carlos|Garcia, Elena|Alvarez, Rafael|de Vicente, Emilio|Quijano, Yolanda|Hernando, Ovidio|Rubio, Carmen|Perea, Sofia|Sanchez, Gema|Hidalgo, Manuel
PMID: 24517959
Journal: Int J Biochem Cell Biol. 2016 Feb;71:24-34.
Title: Enhancement of oxaliplatin sensitivity in human colorectal cancer by hypericin mediated photodynamic therapy via ROS-related mechanism.
Author: Lin, Shengchao|Lei, Kecheng|Du, Wenpei|Yang, Liyan|Shi, Haiyang|Gao, Yuwei|Yin, Peihao|Liang, Xin|Liu, Jianwen
PMID: 26673998
Journal: Int J Mol Med. 2016 Feb;37(2):319-28.
Title: Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis.
Author: Shimamoto, Yuji|Nukatsuka, Mamoru|Takechi, Teiji|Fukushima, Masakazu
PMID: 26676887
Journal: Chin Med J (Engl). 2016 Mar 5;129(5):586-93.
Title: Excision Repair Cross-complementation Group 1 is a Prognostic Biomarker in Patients with Colorectal Cancer Receiving Chemotherapy.
Author: Li, Mu-Xing|Bi, Xin-Yu|Zhao, Hong|Huang, Zhen|Han, Yue|Zhao, Dong-Bin|Zhao, Jian-Jun|Cai, Jian-Qiang
PMID: 26904994
Journal: Pharmacogenomics. 2016 Oct;17(15):1725-1732.
Title: Pharmacogenetic and ethnicity influence on oxaliplatin therapy for colorectal cancer: a meta-analysis.
Author: Shahnam, Adel|Ridha, Zainab|Wiese, Michael D|Kichenadasse, Ganessan|Sorich, Michael J
PMID: 27636246
Journal: Exp Mol Pathol. 2017 Feb;102(1):78-85.
Title: ERCC1 and ERCC2 as predictive biomarkers to oxaliplatin-based chemotherapy in colorectal cancer patients from Egypt.
Author: Kassem, Amira B|Salem, Salem Eid|Abdelrahim, Mohamed E|Said, Amira S A|Salahuddin, Ahmad|Hussein, Marwa Mahmoud|Bahnassy, Abeer A
PMID: 28088319
Journal: J Oncol Pract. 2017 Mar;13(3):e185-e196.
Title: Medical Oncologists' Experiences in Using Genomic Testing for Lung and Colorectal Cancer Care.
Author: Gray, Stacy W|Kim, Benjamin|Sholl, Lynette|Cronin, Angel|Parikh, Aparna R|Klabunde, Carrie N|Kahn, Katherine L|Haggstrom, David A|Keating, Nancy L
PMID: 28095174
Journal: J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title: Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author: Borazanci, Erkut|Millis, Sherri Z|Kimbrough, Jeffery|Doll, Nancy|Von Hoff, Daniel|Ramanathan, Ramesh K
PMID: 28280620
Journal: Exp Oncol. 2017 Mar;39(1):17-24.
Title: Effect of antitumor drugs in low concentrationson the biological, immunophenotypic and cytogenetic characteristics of human colon cancer cells in vitro.
Author: Bezdenezhnykh, N|Kovalova, O|Lykhova, O|Kocherga, R|Vorontsova, A|Zhylchuk, V|Maksimyak, G I|Kudryavets, Yu
PMID: 28361849
Journal: Anticancer Res. 2017 May;37(5):2307-2313.
Title: The Contribution of Excision Repair Cross-complementing Group 1 Genotypes to Colorectal Cancer Susceptibility in Taiwan.
Author: Yueh, Te-Cheng|Chou, An-Kuo|Gong, Chi-Li|Fu, Chun-Kai|Pei, Jen-Sheng|Wu, Ming-Hsien|Tsai, Chia-Wen|Chang, Wen-Shin|Hsiao, Chieh-Lun|Yen, Shiou-Ting|Li, Hsin-Ting|Bau, DA-Tian
PMID: 28476796
Journal: World J Surg. 2017 Nov;41(11):2884-2897.
Title: Relationship Between Expression of Proteins ERCC1, ERCC2, and XRCC1 and Clinical Outcomes in Patients with Rectal Cancer Treated with FOLFOX-Based Preoperative Chemoradiotherapy.
Author: Huang, Ming-Yii|Huang, Joh-Jong|Huang, Chun-Ming|Lin, Chih-Hung|Tsai, Hsiang-Lin|Huang, Ching-Wen|Chai, Chee-Yin|Lin, Chia-Yang|Wang, Jaw-Yuan
PMID: 28608017
Journal: PLoS One. 2017 Aug 2;12(8):e0181615.
Title: Systematic immunohistochemical screening for mismatch repair and ERCC1 gene expression from colorectal cancers in China: Clinicopathological characteristics and effects on survival.
Author: Li, Pan|Xiao, Zhitao|Braciak, Todd A|Ou, Qingjian|Chen, Gong|Oduncu, Fuat S
PMID: 28767665
Journal: Int J Mol Med. 2017 Nov;40(5):1457-1465.
Title: Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer.
Author: Toth, Csaba|Sukosd, Farkas|Valicsek, Erzsebet|Herpel, Esther|Schirmacher, Peter|Renner, Marcus|Mader, Christoph|Tiszlavicz, Laszlo|Kriegsmann, Jorg
PMID: 28949378
Journal: Oncol Res Treat. 2017;40(11):702-706.
Title: Evidence for an Association of ERCC1 Expression and Mismatch Repair Status with Overall Survival in Colorectal Cancer Patients.
Author: Li, Pan|Xiao, Zhi-Tao|Braciak, Todd A|Ou, Qing-Jian|Chen, Gong|Oduncu, Fuat S
PMID: 29065415
Journal: Turk J Med Sci. 2017 Nov 13;47(5):1549-1554.
Title: Polymorphisms of cancer-related genes and risk of multipleprimary malignancies involving colorectal cancer
Author: Cao, Peiguo|Yu, Li|Wu, Anshan|Li, Jingjing|Liu, Ling|Liu, Chunlan|Zhou, Jianda|Cao, Ke|Guo, Chengxian
PMID: 29151331
Journal: Cancer Genet. 2017 Dec;218-219:51-57.
Title: Correlations between microsatellite instability, ERCC1/XRCC1 polymorphism and clinical characteristics, and FOLFOX adjuvant chemotherapy effect of colorectal cancer patients.
Author: Zhang, Liping|Zhao, Jiangman|Yu, Bin|Song, Xinjiang|Sun, Guogang|Han, Lijiang|Wang, Lu|Dong, Shu
PMID: 29153096
Journal: Crit Rev Eukaryot Gene Expr. 2017;27(3):267-275.
Title: Association of ERCC1 Polymorphisms with the Risk of Colorectal Cancer: A Meta-Analysis.
Author: Chen, Jianfeng|Sun, Ningjie|Hu, Gang|Chen, Xiansheng|Jiang, Jiansong|Wu, Haiming|Luo, Gaojian
PMID: 29199611
Journal: Gene. 2018 Feb 20;644:66-73.
Title: Promoter methylation and expression of DNA repair genes MGMT and ERCC1 in tissue and blood of rectal cancer patients.
Author: Shalaby, Sally M|El-Shal, Amal S|Abdelaziz, Lobna A|Abd-Elbary, Eman|Khairy, Mostafa M
PMID: 29080834
Journal: Ann Oncol. 2018 Feb 1;29(2):439-444.
Title: Genotype-based selection of treatment of patients with advanced colorectal cancer (SETICC): a pharmacogenetic-based randomized phase II trial.
Author: Abad, A|Martinez-Balibrea, E|Vieitez, J M|Alonso-Orduna, V|Garcia Alfonso, P|Manzano, J L|Massuti, B|Benavides, M|Carrato, A|Zanui, M|Gallego, J|Gravalos, C|Conde, V|Provencio, M|Valladares-Ayerbes, M|Salazar, R|Sastre, J|Montagut, C|Rivera, F|Aranda, E
PMID: 29145602
Journal: Mol Cancer Res. 2018 Mar;16(3):403-416.
Title: Differential Regulation of LET-7 by LIN28B Isoform-Specific Functions.
Author: Mizuno, Rei|Chatterji, Priya|Andres, Sarah|Hamilton, Kathryn|Simon, Lauren|Foley, Shawn W|Jeganathan, Arjun|Gregory, Brian D|Madison, Blair|Rustgi, Anil K
PMID: 29330293
Journal: Oncol Lett. 2018 Mar;15(3):3586-3593.
Title: Loss of CDX2 gene expression is associated with DNA repair proteins and is a crucial member of the Wnt signaling pathway in liver metastasis of colorectal cancer.
Author: Toth, Csaba|Sukosd, Farkas|Valicsek, Erzsebet|Herpel, Esther|Schirmacher, Peter|Tiszlavicz, Laszlo
PMID: 29467879
Journal: Cancer Med. 2018 Apr;7(4):1264-1274.
Title: The polymorphisms of miRNA-binding site in MLH3 and ERCC1 were linked to the risk of colorectal cancer in a case-control study.
Author: Zhang, Qianye|Zheng, Xiao|Li, Xiaoxia|Sun, Deyu|Xue, Ping|Zhang, Guopei|Xiao, Mingyang|Cai, Yuan|Jin, Cuihong|Yang, Jinghua|Wu, Shengwen|Lu, Xiaobo
PMID: 29516665
Journal: Biomed Res Int. 2018 Jan 15;2018:9651320.
Title: The Differential Expression of Core Genes in Nucleotide Excision Repair Pathway Indicates Colorectal Carcinogenesis and Prognosis.
Author: Liu, Jingwei|Li, Hao|Sun, Liping|Feng, Xue|Wang, Zhenning|Yuan, Yuan|Xing, Chengzhong
PMID: 29568775
Journal: J Surg Res. 2018 Jul;227:158-167.
Title: Using patient-derived xenograft models of colorectal liver metastases to predict chemosensitivity.
Author: Brown, Kai M|Xue, Aiqun|Julovi, Sohel M|Gill, Anthony J|Pavlakis, Nick|Samra, Jaswinder S|Smith, Ross C|Hugh, Thomas J
PMID: 29804848
Journal: Mol Clin Oncol. 2018 Jul;9(1):3-10.
Title: Thymidylate synthase expression in primary colorectal cancer as a predictive marker for the response to 5-fluorouracil- and oxaliplatin-based preoperative chemotherapy for liver metastases.
Author: Takeyama, Hiroshi|Wakasa, Tomoko|Inoue, Keisuke|Kitani, Kotaro|Tsujie, Masanori|Ogawa, Takafumi|Yukawa, Masao|Ohta, Yoshio|Inoue, Masatoshi
PMID: 29977534
Journal: Pharmacology. 2018;102(3-4):161-168.
Title: Unexpected Growth-Promoting Effect of Oxaliplatin in Excision Repair Cross-Complementation Group 1 Transfected Human Colon Cancer Cells.
Author: Jordheim, Lars Petter|Chettab, Kamel|Cros-Perrial, Emeline|Matera, Eva-Laure|Dumontet, Charles
PMID: 30048976
Journal: Front Oncol. 2018 Jul 31;8:290.
Title: Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation.
Author: Hu, Liang-Bo|Chen, Yin|Meng, Xiao-Dong|Yu, Pan|He, Xu|Li, Jie
PMID: 30109214