Primary Site >> Stomach Cancer
Gene >> ERBB4
| 1. | |||||||||||
| Journal: | Gastroenterology. 1999 Nov;117(5):1119-27. | ||||||||||
| Title: | Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells. | ||||||||||
| Author: | Noguchi, H|Sakamoto, C|Wada, K|Akamatsu, T|Uchida, T|Tatsuguchi, A|Matsui, H|Fukui, H|Fujimori, T|Kasuga, M | ||||||||||
| PMID: | 10535875 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2001 Apr 19;20(17):2101-11. | ||||||||||
| Title: | Expression of a truncated 100 kDa HER2 splice variant acts as an endogenous inhibitor of tumour cell proliferation. | ||||||||||
| Author: | Aigner, A|Juhl, H|Malerczyk, C|Tkybusch, A|Benz, C C|Czubayko, F | ||||||||||
| PMID: | 11360194 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 2006 Mar 15;118(6):1426-9. | ||||||||||
| Title: | Somatic mutations of the ERBB4 kinase domain in human cancers. | ||||||||||
| Author: | Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Wang, Young Pil|Jo, Keon Hyun|Moon, Seok Whan|Park, Won Sang|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 16187281 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Dec 1;14(23):7843-9. | ||||||||||
| Title: | High expression of HER3 is associated with a decreased survival in gastric cancer. | ||||||||||
| Author: | Hayashi, Mikiko|Inokuchi, Mikito|Takagi, Yoko|Yamada, Hiroyuki|Kojima, Kazuyuki|Kumagai, Jiro|Kawano, Tatsuyuki|Sugihara, Kenichi | ||||||||||
| PMID: | 19047113 | ||||||||||
| 5. | |||||||||||
| Journal: | J Mol Med (Berl). 2010 Nov;88(11):1113-21. | ||||||||||
| Title: | Targeting the epidermal growth factor receptor (HER) family by T cell receptor gene-modified T lymphocytes. | ||||||||||
| Author: | Meyerhuber, Peter|Conrad, Heinke|Starck, Lilian|Leisegang, Matthias|Busch, Dirk H|Uckert, Wolfgang|Bernhard, Helga | ||||||||||
| PMID: | 20700725 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Oncol. 2010 Nov;37(5):1219-28. | ||||||||||
| Title: | Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer. | ||||||||||
| Author: | Lo Nigro, Cristiana|Monteverde, Martino|Riba, Michela|Lattanzio, Laura|Tonissi, Federica|Garrone, Ornella|Heouaine, Abdelhamid|Gallo, Fabio|Ceppi, Marcello|Borghi, Felice|Comino, Alberto|Merlano, Marco | ||||||||||
| PMID: | 20878069 | ||||||||||
| 7. | |||||||||||
| Journal: | J Clin Oncol. 2011 Aug 1;29(22):3030-6. | ||||||||||
| Title: | Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome. | ||||||||||
| Author: | Begnami, Maria D|Fukuda, Emy|Fregnani, Jose H T G|Nonogaki, Suely|Montagnini, Andre L|da Costa, Wilson L Jr|Soares, Fernando A | ||||||||||
| PMID: | 21709195 | ||||||||||
| 8. | |||||||||||
| Journal: | Mol Med Rep. 2011 Nov-Dec;4(6):1151-5. | ||||||||||
| Title: | The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma. | ||||||||||
| Author: | Ebi, Masahide|Kataoka, Hiromi|Shimura, Takaya|Hirata, Yoshikazu|Mizushima, Takashi|Mizoshita, Tsutomu|Tanaka, Mamoru|Tsukamoto, Hironobu|Ozeki, Keiji|Tanida, Satoshi|Kamiya, Takeshi|Inagaki, Hiroshi|Joh, Takashi | ||||||||||
| PMID: | 21805036 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Cancer Ther. 2012 Feb;11(2):439-51. | ||||||||||
| Title: | Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer. | ||||||||||
| Author: | Nam, Hyun-Jin|Ching, Keith A|Kan, Julie|Kim, Hwang-Phill|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Christensen, James G|Oh, Do-Youn|Bang, Yung-Jue | ||||||||||
| PMID: | 22135232 | ||||||||||
| 10. | |||||||||||
| Journal: | Jpn J Clin Oncol. 2012 Apr;42(4):278-86. | ||||||||||
| Title: | Safety, efficacy and pharmacokinetics of neratinib (HKI-272) in Japanese patients with advanced solid tumors: a Phase 1 dose-escalation study. | ||||||||||
| Author: | Ito, Yoshinori|Suenaga, Mitsukuni|Hatake, Kiyohiko|Takahashi, Shunji|Yokoyama, Masahiro|Onozawa, Yusuke|Yamazaki, Kentaro|Hironaka, Shuichi|Hashigami, Kiyoshi|Hasegawa, Hirotaka|Takenaka, Nobuko|Boku, Narikazu | ||||||||||
| PMID: | 22371427 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Mol Sci. 2012;13(4):4714-26. | ||||||||||
| Title: | Frequent gene amplification predicts poor prognosis in gastric cancer. | ||||||||||
| Author: | Shi, Jing|Yao, Demao|Liu, Wei|Wang, Na|Lv, Hongjun|He, Nongyue|Shi, Bingyin|Hou, Peng|Ji, Meiju | ||||||||||
| PMID: | 22606006 | ||||||||||
| 12. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jul;16(7):668-72. | ||||||||||
| Title: | [Clinical significance of human epidermal growth factor receptor family molecules expression in gastric cancer]. | ||||||||||
| Author: | Li, Gang|Gu, Rong-min|Wen, Xu|Ming, Xue-zhi|Xia, Lei|Xu, Xin-yu|Zhang, Ji|Chen, Huan-qiu | ||||||||||
| PMID: | 23888453 | ||||||||||
| 13. | |||||||||||
| Journal: | Gastric Cancer. 2014 Jan;17(1):76-86. | ||||||||||
| Title: | Prognostic value of epidermal growth factor receptors in gastric cancer: a survival analysis by Weibull model incorporating long-term survivors. | ||||||||||
| Author: | Jacome, Alexandre Andrade Anjos|Wohnrath, Durval R|Scapulatempo Neto, Cristovam|Carneseca, Estela C|Serrano, Sergio V|Viana, Luciano Souza|Nunes, Joao S|Martinez, Edson Z|Santos, Jose Sebastiao | ||||||||||
| PMID: | 23455716 | ||||||||||
| 14. | |||||||||||
| Journal: | J Hematol Oncol. 2014 Mar 11;7:22. | ||||||||||
| Title: | A phase I study of AST1306, a novel irreversible EGFR and HER2 kinase inhibitor, in patients with advanced solid tumors. | ||||||||||
| Author: | Zhang, Jian|Cao, Junning|Li, Jin|Zhang, Yifan|Chen, Zhiyu|Peng, Wei|Sun, Si|Zhao, Naiqing|Wang, Jiachen|Zhong, Dafang|Zhang, Xiaofang|Zhang, Jing | ||||||||||
| PMID: | 24612546 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2014 Apr 11;9(4):e94606. | ||||||||||
| Title: | Expression of the EGF family in gastric cancer: downregulation of HER4 and its activating ligand NRG4. | ||||||||||
| Author: | Nielsen, Trine Ostergaard|Friis-Hansen, Lennart|Poulsen, Steen Seier|Federspiel, Birgitte|Sorensen, Boe Sandahl | ||||||||||
| PMID: | 24728052 | ||||||||||
| 16. | |||||||||||
| Journal: | Biomed Pharmacother. 2014 Jul;68(6):809-12. | ||||||||||
| Title: | The role of HER3 in gastric cancer. | ||||||||||
| Author: | Wang, Liying|Yuan, Hengheng|Li, Yanjing|Han, Yu | ||||||||||
| PMID: | 25194439 | ||||||||||
| 17. | |||||||||||
| Journal: | Anticancer Res. 2014 Nov;34(11):6405-15. | ||||||||||
| Title: | High-density array comparative genomic hybridization detects novel copy number alterations in gastric adenocarcinoma. | ||||||||||
| Author: | Seabra, Aline Damasceno|Araujo, Taissa Maira Thomaz|Mello Junior, Fernando Augusto Rodrigues|Di Felipe Avila Alcantara, Diego|De Barros, Amanda Paiva|De Assumpcao, Paulo Pimentel|Montenegro, Raquel Carvalho|Guimaraes, Adriana Costa|Demachki, Samia|Burbano | ||||||||||
| PMID: | 25368240 | ||||||||||
| 18. | |||||||||||
| Journal: | J Clin Pathol. 2015 May;68(5):374-80. | ||||||||||
| Title: | Protein expression of HER2, 3, 4 in gastric cancer: correlation with clinical features and survival. | ||||||||||
| Author: | He, Xiao Xiao|Ding, Li|Lin, Yuan|Shu, Man|Wen, Jian Ming|Xue, Ling | ||||||||||
| PMID: | 25731189 | ||||||||||
| 19. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1107-12. | ||||||||||
| Title: | Mutational landscape of gastric adenocarcinoma in Chinese: implications for prognosis and therapy. | ||||||||||
| Author: | Chen, Kexin|Yang, Da|Li, Xiangchun|Sun, Baocun|Song, Fengju|Cao, Wenfeng|Brat, Daniel J|Gao, Zhibo|Li, Haixin|Liang, Han|Zhao, Yanrui|Zheng, Hong|Li, Miao|Buckner, Jan|Patterson, Scott D|Ye, Xiang|Reinhard, Christoph|Bhathena, Anahita|Joshi, Deepa|Mischel | ||||||||||
| PMID: | 25583476 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncotarget. 2016 Feb 16;7(7):8055-66. | ||||||||||
| Title: | Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites. | ||||||||||
| Author: | Lim, Byungho|Kim, Chan|Kim, Jeong-Hwan|Kwon, Woo Sun|Lee, Won Seok|Kim, Jeong Min|Park, Jun Yong|Kim, Hyo Song|Park, Kyu Hyun|Kim, Tae Soo|Park, Jong-Lyul|Chung, Hyun Cheol|Rha, Sun Young|Kim, Seon-Young | ||||||||||
| PMID: | 26811494 | ||||||||||
| 21. | |||||||||||
| Journal: | Lancet Oncol. 2016 Mar;17(3):367-77. | ||||||||||
| Title: | Neratinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (ExteNET): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. | ||||||||||
| Author: | Chan, Arlene|Delaloge, Suzette|Holmes, Frankie A|Moy, Beverly|Iwata, Hiroji|Harvey, Vernon J|Robert, Nicholas J|Silovski, Tajana|Gokmen, Erhan|von Minckwitz, Gunter|Ejlertsen, Bent|Chia, Stephen K L|Mansi, Janine|Barrios, Carlos H|Gnant, Michael|Buyse, Ma | ||||||||||
| PMID: | 26874901 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2016 Apr 5;7(14):18424-39. | ||||||||||
| Title: | Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer. | ||||||||||
| Author: | Arienti, Chiara|Zanoni, Michele|Pignatta, Sara|Del Rio, Alberto|Carloni, Silvia|Tebaldi, Michela|Tedaldi, Gianluca|Tesei, Anna | ||||||||||
| PMID: | 26919099 | ||||||||||
| 23. | |||||||||||
| Journal: | Anticancer Res. 2016 Apr;36(4):1581-90. | ||||||||||
| Title: | HER Family Protein Expression in a Greek Population with Gastric Cancer. A Retrospective Hellenic Cooperative Oncology Group Study. | ||||||||||
| Author: | Makatsoris, Thomas|Tsamandas, Athanassios C|Strimpakos, Alexios|Alexopoulou, Zoi|Dionysopoulos, Dimitrios|Pervana, Stavroula|Konstantara, Athina|Papakostas, Pavlos|Samantas, Epaminontas|Rallis, Grigoris|Dimou, Anastasios|Pentheroudakis, George|Papaparaske | ||||||||||
| PMID: | 27069134 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 12;7(28):43894-43906. | ||||||||||
| Title: | Whole-exome sequencing to identify somatic mutations in peritoneal metastatic gastric adenocarcinoma: A preliminary study. | ||||||||||
| Author: | Liu, Hao|Li, Fengping|Zhu, Yu|Li, Tingting|Huang, Haipeng|Lin, Tian|Hu, Yanfeng|Qi, Xiaolong|Yu, Jiang|Li, Guoxin | ||||||||||
| PMID: | 27270314 | ||||||||||
| 25. | |||||||||||
| Journal: | PLoS One. 2016 Aug 18;11(8):e0161219. | ||||||||||
| Title: | HER3, but Not HER4, Plays an Essential Role in the Clinicopathology and Prognosis of Gastric Cancer: A Meta-Analysis. | ||||||||||
| Author: | Cao, Guo-Dong|Chen, Ke|Xiong, Mao-Ming|Chen, Bo | ||||||||||
| PMID: | 27536774 | ||||||||||
| 26. | |||||||||||
| Journal: | Cell Death Dis. 2016 Oct 27;7(10):e2442. | ||||||||||
| Title: | Increased expression of EHF via gene amplification contributes to the activation of HER family signaling and associates with poor survival in gastric cancer. | ||||||||||
| Author: | Shi, Jing|Qu, Yiping|Li, Xinru|Sui, Fang|Yao, Demao|Yang, Qi|Shi, Bingyin|Ji, Meiju|Hou, Peng | ||||||||||
| PMID: | 27787520 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncotarget. 2017 Jul 11;8(28):45725-45735. | ||||||||||
| Title: | miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression. | ||||||||||
| Author: | Song, Guangyuan|Zhang, Hongcheng|Chen, Chenlin|Gong, Lijie|Chen, Biao|Zhao, Shaoyun|Shi, Ji|Xu, Ji|Ye, Zaiyuan | ||||||||||
| PMID: | 28501849 | ||||||||||
| 28. | |||||||||||
| Journal: | NPJ Precis Oncol. 2017 May 1;1(1):9. | ||||||||||
| Title: | Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival. | ||||||||||
| Author: | Leong, Siew Hong|Lwin, Kyaw Myo|Lee, Sze Sing|Ng, Wai Har|Ng, Kia Min|Tan, Soo Yong|Ng, Bee Ling|Carter, Nigel P|Tang, Carol|Lian Kon, Oi | ||||||||||
| PMID: | 29872697 | ||||||||||
| 29. | |||||||||||
| Journal: | Acta Gastroenterol Belg. 2017 Jan-Mar;80(1):31-37. | ||||||||||
| Title: | Immunohistochemical expression of CDX2, CK7, HER2 and HER4 in periampullary adenocarcinoma : implications for clinicopathology and patient outcomes. | ||||||||||
| Author: | Ugras, Nesrin|Yerci, Omer|Ozgun, Gonca|Deligonul, Adem|Dundar, Halit Ziya|Sarkut, Pinar|Kanat, Ozkan | ||||||||||
| PMID: | 29364095 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 29;8(32):52584-52593. | ||||||||||
| Title: | siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells. | ||||||||||
| Author: | Yuan, Heng-Heng|Yang, Ying-Nan|Zhou, Jian-Hua|Li, Yan-Jing|Wang, Li-Ying|Qin, Jun-Wei|Liu, Tao|Li, Zhen-Zhen|Zhou, Qing-Xin|Wei, Xiao-Li|Zhang, Ting-Ting|Huang, Peng|Zhang, Wen-Jie|Liu, Lei|Du, Xiao-Xue|Han, Yu | ||||||||||
| PMID: | 28881753 | ||||||||||
| 31. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2017 Mar 4;484(2):248-254. | ||||||||||
| Title: | Development of a highly specific HER2 monoclonal antibody for immunohistochemistry using protein microarray chips. | ||||||||||
| Author: | Qi, Lili|Zhou, Lixin|Lu, Mingmin|Yuan, Kehu|Li, Zhongwu|Wu, Guiyin|Huang, Xiaozheng|Shen, Yi|Zhao, Min|Fu, Wei|Chu, Boyang|Wang, Guangli|Ren, Fangfang|Ma, Donghui|Chen, Jian | ||||||||||
| PMID: | 28111342 | ||||||||||
| 32. | |||||||||||
| Journal: | Gastric Cancer. 2018 Mar;21(2):225-236. | ||||||||||
| Title: | Clinical significance of overexpression of NRG1 and its receptors, HER3 and HER4, in gastric cancer patients. | ||||||||||
| Author: | Yun, Sumi|Koh, Jiwon|Nam, Soo Kyung|Park, Jung Ok|Lee, Sung Mi|Lee, Kyoungyul|Lee, Kyu Sang|Ahn, Sang-Hoon|Park, Do Joong|Kim, Hyung-Ho|Choe, Gheeyoung|Kim, Woo Ho|Lee, Hye Seung | ||||||||||
| PMID: | 28573357 | ||||||||||
| 33. | |||||||||||
| Journal: | Cell Biol Int. 2018 Jan;42(1):53-62. | ||||||||||
| Title: | 4-Phenybutyric acid promotes gastric cancer cell migration via histone deacetylase inhibition-mediated HER3/HER4 up-regulation. | ||||||||||
| Author: | Shi, Xiaonan|Zheng, Chunlei|Li, Ce|Hou, Kezuo|Wang, Xiaoxun|Yang, Zichang|Liu, Chang|Liu, Yunpeng|Che, Xiaofang|Qu, Xiujuan | ||||||||||
| PMID: | 28851073 | ||||||||||
| 34. | |||||||||||
| Journal: | Cancer Res Treat. 2018 Jul;50(3):835-842. | ||||||||||
| Title: | Phase 1 Studies of Poziotinib, an Irreversible Pan-HER Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors. | ||||||||||
| Author: | Kim, Tae Min|Lee, Keun-Wook|Oh, Do-Youn|Lee, Jong-Seok|Im, Seock-Ah|Kim, Dong-Wan|Han, Sae-Won|Kim, Yu Jung|Kim, Tae-You|Kim, Jee Hyun|Han, Hyesun|Kim, Woo Ho|Bang, Yung-Jue | ||||||||||
| PMID: | 28859471 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncogene. 2018 May;37(22):3022-3038. | ||||||||||
| Title: | The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition. | ||||||||||
| Author: | Shi, Jiaolong|Li, Fengping|Yao, Xingxing|Mou, Tingyu|Xu, Zhijun|Han, Zheng|Chen, Siyu|Li, Wende|Yu, Jiang|Qi, Xiaolong|Liu, Hao|Li, Guoxin | ||||||||||
| PMID: | 29535422 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Rep. 2018 Jun;39(6):2892-2898. | ||||||||||
| Title: | ERBB4 promotes the proliferation of gastric cancer cells via the PI3K/Akt signaling pathway. | ||||||||||
| Author: | Xu, Ji|Gong, Lijie|Qian, Zhenyuan|Song, Guangyuan|Liu, Jinming | ||||||||||
| PMID: | 29620274 | ||||||||||
| 37. | |||||||||||
| Journal: | Oncol Lett. 2018 Oct;16(4):4863-4870. | ||||||||||
| Title: | Landscape of somatic mutations in gastric cancer assessed using next-generation sequencing analysis. | ||||||||||
| Author: | Pan, Xuan|Ji, Xiaozhi|Zhang, Renmin|Zhou, Zhaofei|Zhong, Yuejiao|Peng, Wei|Sun, Ning|Xu, Xinyu|Xia, Lei|Li, Pansong|Lu, Jianwei|Tu, Jing | ||||||||||
| PMID: | 30250552 | ||||||||||