Primary Site >> Stomach Cancer

Gene >> ERBB3

Journal: Biochem Biophys Res Commun. 1993 May 14;192(3):1189-97.
Title: c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase.
Author: Katoh, M|Yazaki, Y|Sugimura, T|Terada, M
PMID: 7685162
Journal: Gastroenterology. 1999 Nov;117(5):1119-27.
Title: Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells.
Author: Noguchi, H|Sakamoto, C|Wada, K|Akamatsu, T|Uchida, T|Tatsuguchi, A|Matsui, H|Fukui, H|Fujimori, T|Kasuga, M
PMID: 10535875
Journal: J Biol Chem. 2002 Apr 5;277(14):11918-26.
Title: Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.
Author: Pero, Stephanie C|Oligino, Lyn|Daly, Roger J|Soden, Amy L|Liu, Chen|Roller, Peter P|Li, Peng|Krag, David N
PMID: 11809769
Journal: Oncogene. 2003 Mar 6;22(9):1294-301.
Title: Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas.
Author: Kobayashi, Michimoto|Iwamatsu, Akihiro|Shinohara-Kanda, Azusa|Ihara, Sayoko|Fukui, Yasuhisa
PMID: 12618754
Journal: Int J Cancer. 2006 Mar 15;118(6):1426-9.
Title: Somatic mutations of the ERBB4 kinase domain in human cancers.
Author: Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Wang, Young Pil|Jo, Keon Hyun|Moon, Seok Whan|Park, Won Sang|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 16187281
Journal: Carcinogenesis. 2008 Apr;29(4):704-12.
Title: Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells.
Author: Kim, Kwang-Kyu|Lee, Jung Joon|Yang, Young|You, Kwan-Hee|Lee, Jeong-Hyung
PMID: 18258606
Journal: Cancer Res. 2008 Apr 1;68(7):2340-8.
Title: FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.
Author: Kunii, Kaiko|Davis, Lenora|Gorenstein, Julie|Hatch, Harold|Yashiro, Masakazu|Di Bacco, Alessandra|Elbi, Cem|Lutterbach, Bart
PMID: 18381441
Journal: Clin Cancer Res. 2008 Dec 1;14(23):7843-9.
Title: High expression of HER3 is associated with a decreased survival in gastric cancer.
Author: Hayashi, Mikiko|Inokuchi, Mikito|Takagi, Yoko|Yamada, Hiroyuki|Kojima, Kazuyuki|Kumagai, Jiro|Kawano, Tatsuyuki|Sugihara, Kenichi
PMID: 19047113
Journal: Anat Rec (Hoboken). 2009 Feb;292(2):262-70.
Title: Gene expression profiling in TWIST-depleted gastric cancer cells.
Author: Feng, Mei-Yan|Wang, Kuan|Shi, Qing-Tao|Yu, Xiu-Wen|Geng, Jing-Shu
PMID: 19051271
Journal: World J Surg. 2009 Oct;33(10):2112-8.
Title: Comparative study on overexpression of HER2/neu and HER3 in gastric cancer.
Author: Zhang, Xiu Li|Yang, Yun Sheng|Xu, Dong Ping|Qu, Jian Hui|Guo, Ming Zhou|Gong, Yan|Huang, Jin
PMID: 19636613
Journal: Mol Cancer Ther. 2009 Sep;8(9):2526-36.
Title: Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells.
Author: Yoon, Young-Kwang|Kim, Hwang-Phill|Han, Sae-Won|Hur, Hyung-Seok|Oh, Do Youn|Im, Seock-Ah|Bang, Yung-Jue|Kim, Tae-You
PMID: 19755509
Journal: Mol Cancer. 2010 May 26;9:121.
Title: Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition.
Author: Corso, Simona|Ghiso, Elena|Cepero, Virna|Sierra, J Rafael|Migliore, Cristina|Bertotti, Andrea|Trusolino, Livio|Comoglio, Paolo M|Giordano, Silvia
PMID: 20500904
Journal: J Mol Med (Berl). 2010 Nov;88(11):1113-21.
Title: Targeting the epidermal growth factor receptor (HER) family by T cell receptor gene-modified T lymphocytes.
Author: Meyerhuber, Peter|Conrad, Heinke|Starck, Lilian|Leisegang, Matthias|Busch, Dirk H|Uckert, Wolfgang|Bernhard, Helga
PMID: 20700725
Journal: Surg Today. 2011 Jan;41(1):24-38.
Title: Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications.
Author: Yamashita, Keishi|Sakuramoto, Shinichi|Watanabe, Masahiko
PMID: 21191688
Journal: Clin Cancer Res. 2011 Aug 1;17(15):5060-70.
Title: Pertuzumab in combination with trastuzumab shows significantly enhanced antitumor activity in HER2-positive human gastric cancer xenograft models.
Author: Yamashita-Kashima, Yoriko|Iijima, Shigeyuki|Yorozu, Keigo|Furugaki, Koh|Kurasawa, Mitsue|Ohta, Masateru|Fujimoto-Ouchi, Kaori
PMID: 21700765
Journal: J Clin Oncol. 2011 Aug 1;29(22):3030-6.
Title: Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome.
Author: Begnami, Maria D|Fukuda, Emy|Fregnani, Jose H T G|Nonogaki, Suely|Montagnini, Andre L|da Costa, Wilson L Jr|Soares, Fernando A
PMID: 21709195
Journal: Gastroenterology. 2011 Nov;141(5):1738-48.e1-2.
Title: DARPP-32 increases interactions between epidermal growth factor receptor and ERBB3 to promote tumor resistance to gefitinib.
Author: Zhu, Shoumin|Belkhiri, Abbes|El-Rifai, Wael
PMID: 21741919
Journal: Mol Cancer Ther. 2012 Feb;11(2):439-51.
Title: Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer.
Author: Nam, Hyun-Jin|Ching, Keith A|Kan, Julie|Kim, Hwang-Phill|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Christensen, James G|Oh, Do-Youn|Bang, Yung-Jue
PMID: 22135232
Journal: Invest New Drugs. 2012 Aug;30(4):1352-60.
Title: Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks.
Author: Kataoka, Yu|Mukohara, Toru|Tomioka, Hideo|Funakoshi, Yohei|Kiyota, Naomi|Fujiwara, Yutaka|Yashiro, Masakazu|Hirakawa, Kosei|Hirai, Midori|Minami, Hironobu
PMID: 21655918
Journal: Curr Pharm Des. 2013;19(5):958-64.
Title: Irinotecan resistance is accompanied by upregulation of EGFR and Src signaling in human cancer models.
Author: Petitprez, Amelie|Larsen, Annette K
PMID: 22973964
Journal: Gut Microbes. 2013 Nov-Dec;4(6):454-74.
Title: Signal transduction of Helicobacter pylori during interaction with host cell protein receptors of epithelial and immune cells.
Author: Pachathundikandi, Suneesh Kumar|Tegtmeyer, Nicole|Backert, Steffen
PMID: 24280762
Journal: Nat Rev Clin Oncol. 2013 Nov;10(11):643-55.
Title: Gastric cancer-molecular and clinical dimensions.
Author: Wadhwa, Roopma|Song, Shumei|Lee, Ju-Seog|Yao, Yixin|Wei, Qingyi|Ajani, Jaffer A
PMID: 24061039
Journal: Cancer Res. 2013 Oct 1;73(19):6013-23.
Title: Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110alpha inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers.
Author: Garrett, Joan T|Sutton, Cammie R|Kurupi, Richard|Bialucha, Carl Uli|Ettenberg, Seth A|Collins, Scott D|Sheng, Qing|Wallweber, Jerry|Defazio-Eli, Lisa|Arteaga, Carlos L
PMID: 23918797
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jul;16(7):668-72.
Title: [Clinical significance of human epidermal growth factor receptor family molecules expression in gastric cancer].
Author: Li, Gang|Gu, Rong-min|Wen, Xu|Ming, Xue-zhi|Xia, Lei|Xu, Xin-yu|Zhang, Ji|Chen, Huan-qiu
PMID: 23888453
Journal: J Biol Chem. 2013 Aug 30;288(35):25254-64.
Title: Carboxyl group footprinting mass spectrometry and molecular dynamics identify key interactions in the HER2-HER3 receptor tyrosine kinase interface.
Author: Collier, Timothy S|Diraviyam, Karthikeyan|Monsey, John|Shen, Wei|Sept, David|Bose, Ron
PMID: 23843458
Journal: Oncol Rep. 2013 Sep;30(3):1087-93.
Title: Enhanced antitumor activity of trastuzumab emtansine (T-DM1) in combination with pertuzumab in a HER2-positive gastric cancer model.
Author: Yamashita-Kashima, Yoriko|Shu, Sei|Harada, Naoki|Fujimoto-Ouchi, Kaori
PMID: 23783223
Journal: Mol Cancer Ther. 2013 May;12(5):737-46.
Title: Y-box binding protein-1 contributes to both HER2/ErbB2 expression and lapatinib sensitivity in human gastric cancer cells.
Author: Shibata, Tomohiro|Kan, Hitoshi|Murakami, Yuichi|Ureshino, Hiroki|Watari, Kosuke|Kawahara, Akihiko|Kage, Masayoshi|Hattori, Satoshi|Ono, Mayumi|Kuwano, Michihiko
PMID: 23445612
Journal: PLoS One. 2013;8(1):e54644.
Title: A novel proteomics-based clinical diagnostics technology identifies heterogeneity in activated signaling pathways in gastric cancers.
Author: Lee, Jeeyun|Kim, Sung|Kim, Phillip|Liu, Xinjun|Lee, Tani|Kim, Kyoung-Mee|Do, In-Gu|Park, Joon Oh|Park, Se Hoon|Jang, Jiryeon|Hoe, Nicholas|Harvie, Gulia|Kuller, Anne|Jain, Anjali|Meyer, Gary|Leesman, Glen|Park, Young Suk|Choi, Min Gew|Sohn, Tae Sung|Bae,
PMID: 23372746
Journal: J Natl Cancer Inst. 2013 Feb 20;105(4):266-73.
Title: HER3 overexpression and survival in solid tumors: a meta-analysis.
Author: Ocana, Alberto|Vera-Badillo, Francisco|Seruga, Bostjan|Templeton, Arnoud|Pandiella, Atanasio|Amir, Eitan
PMID: 23221996
Journal: Cancer Sci. 2014 Dec;105(12):1591-600.
Title: Immunohistochemical analysis of RTKs expression identified HER3 as a prognostic indicator of gastric cancer.
Author: Ema, Akira|Yamashita, Keishi|Ushiku, Hideki|Kojo, Ken|Minatani, Naoko|Kikuchi, Mariko|Mieno, Hiroaki|Moriya, Hiromitsu|Hosoda, Kei|Katada, Natsuya|Kikuchi, Shiro|Watanabe, Masahiko
PMID: 25455899
Journal: Oncotarget. 2014 Nov 15;5(21):10222-36.
Title: Regulation of ERBB3/HER3 signaling in cancer.
Author: Mujoo, Kalpana|Choi, Byung-Kwon|Huang, Zhao|Zhang, Ningyan|An, Zhiqiang
PMID: 25400118
Journal: Mol Clin Oncol. 2014 Nov;2(6):1160-1166.
Title: Expression of acidosis-dependent genes in human cancer nests.
Author: Fukamachi, Toshihiko|Ikeda, Shunsuke|Saito, Hiromi|Tagawa, Masatoshi|Kobayashi, Hiroshi
PMID: 25279216
Journal: Biomed Pharmacother. 2014 Jul;68(6):809-12.
Title: The role of HER3 in gastric cancer.
Author: Wang, Liying|Yuan, Hengheng|Li, Yanjing|Han, Yu
PMID: 25194439
Journal: Clin Cancer Res. 2014 Sep 1;20(17):4559-73.
Title: Functional genetic approach identifies MET, HER3, IGF1R, INSR pathways as determinants of lapatinib unresponsiveness in HER2-positive gastric cancer.
Author: Zhang, Zhe|Wang, Jiping|Ji, Dongmei|Wang, Chenchen|Liu, Rujiao|Wu, Zheng|Liu, Lian|Zhu, Dan|Chang, Jinjia|Geng, Ruixuan|Xiong, Lei|Fang, Qiangyi|Li, Jin
PMID: 24973425
Journal: APMIS. 2014 Dec;122(12):1207-12.
Title: Mutational and expressional analysis of ERBB3 gene in common solid cancers.
Author: Choi, Mi Ryoung|An, Chang Hyeok|Chung, Yeun Jun|Choi, Youn Jin|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 24909266
Journal: Int J Clin Exp Pathol. 2014 Mar 15;7(4):1449-58. eCollection 2014.
Title: AKT/ERK activation is associated with gastric cancer cell resistance to paclitaxel.
Author: Wu, Gang|Qin, Xue-Qian|Guo, Jing-Jing|Li, Tian-Yi|Chen, Jin-Hong
PMID: 24817940
Journal: PLoS One. 2014 Apr 11;9(4):e94606.
Title: Expression of the EGF family in gastric cancer: downregulation of HER4 and its activating ligand NRG4.
Author: Nielsen, Trine Ostergaard|Friis-Hansen, Lennart|Poulsen, Steen Seier|Federspiel, Birgitte|Sorensen, Boe Sandahl
PMID: 24728052
Journal: Recent Results Cancer Res. 2014;201:125-43.
Title: Lapatinib.
Author: Nolting, Minna|Schneider-Merck, Tanja|Trepel, Martin
PMID: 24756789
Journal: Gastric Cancer. 2014 Jan;17(1):76-86.
Title: Prognostic value of epidermal growth factor receptors in gastric cancer: a survival analysis by Weibull model incorporating long-term survivors.
Author: Jacome, Alexandre Andrade Anjos|Wohnrath, Durval R|Scapulatempo Neto, Cristovam|Carneseca, Estela C|Serrano, Sergio V|Viana, Luciano Souza|Nunes, Joao S|Martinez, Edson Z|Santos, Jose Sebastiao
PMID: 23455716
Journal: Oncogene. 2014 Jun 19;33(25):3334-41.
Title: Testican-1-mediated epithelial-mesenchymal transition signaling confers acquired resistance to lapatinib in HER2-positive gastric cancer.
Author: Kim, H-P|Han, S-W|Song, S-H|Jeong, E-G|Lee, M-Y|Hwang, D|Im, S-A|Bang, Y-J|Kim, T-Y
PMID: 23873022
Journal: Med Oncol. 2014 Apr;31(4):903.
Title: Her3 is associated with poor survival of gastric adenocarcinoma: Her3 promotes proliferation, survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway.
Author: Wu, Xiaoyu|Chen, Yun|Li, Gang|Xia, Lei|Gu, Rongmin|Wen, Xu|Ming, Xuezhi|Chen, Huanqiu
PMID: 24623015
Journal: Mol Clin Oncol. 2014 Mar;2(2):175-181.
Title: Unraveling trastuzumab and lapatinib inefficiency in gastric cancer: Future steps (Review).
Author: Shimoyama, Shouji
PMID: 24649329
Journal: MAbs. 2014 Mar-Apr;6(2):403-8.
Title: The ErbB2-targeting antibody trastuzumab and the small-molecule SRC inhibitor saracatinib synergistically inhibit ErbB2-overexpressing gastric cancer.
Author: Han, Siqi|Meng, Yanchun|Tong, Qing|Li, Guangchao|Zhang, Xunmin|Chen, Yalin|Hu, Shi|Zheng, Lei|Tan, Wenlong|Li, Hui|Chen, Yang|Zhang, Ge|Li, Bohua|Guo, Yajun
PMID: 24492292
Journal: Int J Mol Sci. 2015 Aug 17;16(8):19447-57.
Title: Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma.
Author: Gonzalez-Alonso, Paula|Chamizo, Cristina|Moreno, Victor|Madoz-Gurpide, Juan|Carvajal, Nerea|Daoud, Lina|Zazo, Sandra|Martin-Aparicio, Ester|Cristobal, Ion|Rincon, Raul|Garcia-Foncillas, Jesus|Rojo, Federico
PMID: 26287187
Journal: Oncotarget. 2015 Dec 15;6(40):42868-78.
Title: HER3 over-expression and overall survival in gastrointestinal cancers.
Author: Wang, Yadong|Yang, Haiyan|Duan, Guangcai
PMID: 26517355
Journal: Clin Cancer Res. 2015 Dec 15;21(24):5519-31.
Title: Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas.
Author: Leto, Simonetta M|Sassi, Francesco|Catalano, Irene|Torri, Valter|Migliardi, Giorgia|Zanella, Eugenia R|Throsby, Mark|Bertotti, Andrea|Trusolino, Livio
PMID: 26296355
Journal: PLoS One. 2015 Jul 28;10(7):e0134493.
Title: Patient-Derived Gastric Carcinoma Xenograft Mouse Models Faithfully Represent Human Tumor Molecular Diversity.
Author: Zhang, Tianwei|Zhang, Lin|Fan, Shuqiong|Zhang, Meizhuo|Fu, Haihua|Liu, Yuanjie|Yin, Xiaolu|Chen, Hao|Xie, Liang|Zhang, Jingchuan|Gavine, Paul R|Gu, Yi|Ni, Xingzhi|Su, Xinying
PMID: 26217940
Journal: J Clin Pathol. 2015 May;68(5):374-80.
Title: Protein expression of HER2, 3, 4 in gastric cancer: correlation with clinical features and survival.
Author: He, Xiao Xiao|Ding, Li|Lin, Yuan|Shu, Man|Wen, Jian Ming|Xue, Ling
PMID: 25731189
Journal: Oncotarget. 2015 Feb 10;6(4):2009-22.
Title: Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer.
Author: Chang, Jinjia|Wang, Shanshan|Zhang, Zhe|Liu, Xinyang|Wu, Zheng|Geng, Ruixuan|Ge, Xiaoxiao|Dai, Congqi|Liu, Rujiao|Zhang, Qunling|Li, Wenhua|Li, Jin
PMID: 25576915
Journal: Onco Targets Ther. 2014 Dec 16;8:7-14.
Title: Assessment and prognostic analysis of EGFR, HER2, and HER3 protein expression in surgically resected gastric adenocarcinomas.
Author: Tang, Daoqiang|Liu, Charles Yj|Shen, Danping|Fan, Shuqiong|Su, Xinying|Ye, Peng|Gavine, Paul R|Yin, Xiaolu
PMID: 25565860
Journal: Mol Carcinog. 2015 Dec;54(12):1700-9.
Title: Essential role of Her3 in two signaling transduction patterns: Her2/Her3 and MET/Her3 in proliferation of human gastric cancer.
Author: Yun, Chen|Gang, Li|Rongmin, Gu|Xu, Wen|Xuezhi, Ming|Huanqiu, Chen
PMID: 25400108
Journal: Mol Oncol. 2015 Feb;9(2):398-408.
Title: Combination of novel HER2-targeting antibody 1E11 with trastuzumab shows synergistic antitumor activity in HER2-positive gastric cancer.
Author: Ko, Bong-Kook|Lee, Sook-Yeon|Lee, Young-Ha|Hwang, In-Sik|Persson, Helena|Rockberg, Johan|Borrebaeck, Carl|Park, Dongeun|Kim, Kyu-Tae|Uhlen, Mathias|Lee, Jong-Seo
PMID: 25306393
Journal: Cell Death Dis. 2016 Oct 27;7(10):e2442.
Title: Increased expression of EHF via gene amplification contributes to the activation of HER family signaling and associates with poor survival in gastric cancer.
Author: Shi, Jing|Qu, Yiping|Li, Xinru|Sui, Fang|Yao, Demao|Yang, Qi|Shi, Bingyin|Ji, Meiju|Hou, Peng
PMID: 27787520
Journal: Oncotarget. 2016 Dec 20;7(51):84860-84871.
Title: Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1.
Author: Nonagase, Yoshikane|Yonesaka, Kimio|Kawakami, Hisato|Watanabe, Satomi|Haratani, Koji|Takahama, Takayuki|Takegawa, Naoki|Ueda, Hiroto|Tanizaki, Junko|Hayashi, Hidetoshi|Yoshida, Takeshi|Takeda, Masayuki|Chiba, Yasutaka|Tamura, Takao|Nakagawa, Kazuhiko|Tsur
PMID: 27768588
Journal: Expert Opin Biol Ther. 2016 Dec;16(12):1549-1555.
Title: The prospect of patritumab for treating non-small cell lung cancer.
Author: Horinouchi, Hidehito
PMID: 27744717
Journal: PLoS One. 2016 Aug 18;11(8):e0161219.
Title: HER3, but Not HER4, Plays an Essential Role in the Clinicopathology and Prognosis of Gastric Cancer: A Meta-Analysis.
Author: Cao, Guo-Dong|Chen, Ke|Xiong, Mao-Ming|Chen, Bo
PMID: 27536774
Journal: Mol Cancer Ther. 2016 Sep;15(9):2251-8.
Title: A Phase II Biomarker-Embedded Study of Lapatinib plus Capecitabine as First-line Therapy in Patients with Advanced or Metastatic Gastric Cancer.
Author: LaBonte, Melissa J|Yang, Dongyun|Zhang, Wu|Wilson, Peter M|Nagarwala, Yasir M|Koch, Kevin M|Briner, Colleen|Kaneko, Tomomi|Rha, Sun-Young|Gladkov, Oleg|Urba, Susan G|Sakaeva, Dina|Pishvaian, Michael J|Hsieh, Ruey-Kuen|Lee, Wei-Ping|Lenz, Heinz-Josef
PMID: 27325685
Journal: Cancer Lett. 2016 Sep 28;380(1):20-30.
Title: The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer.
Author: Wang, Qiwei|Zhang, Xiaotian|Shen, Enyun|Gao, Jing|Cao, Fengqi|Wang, Xiaojuan|Li, Yilin|Tian, Tiantian|Wang, Jingyuan|Chen, Zuhua|Wang, Jiayuan|Shen, Lin
PMID: 27317872
Journal: Anticancer Res. 2016 Apr;36(4):1581-90.
Title: HER Family Protein Expression in a Greek Population with Gastric Cancer. A Retrospective Hellenic Cooperative Oncology Group Study.
Author: Makatsoris, Thomas|Tsamandas, Athanassios C|Strimpakos, Alexios|Alexopoulou, Zoi|Dionysopoulos, Dimitrios|Pervana, Stavroula|Konstantara, Athina|Papakostas, Pavlos|Samantas, Epaminontas|Rallis, Grigoris|Dimou, Anastasios|Pentheroudakis, George|Papaparaske
PMID: 27069134
Journal: Oncotarget. 2016 Apr 19;7(16):21601-17.
Title: APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis.
Author: Hong, Se-Hoon|Lee, Won Jae|Kim, Young Doo|Kim, Hyunjoo|Jeon, Young-Jun|Lim, Bitna|Cho, Dong-Hyung|Heo, Won Do|Yang, Doo-Hyun|Kim, Chan-Young|Yang, Han-Kwang|Yang, Jin Kuk|Jung, Yong-Keun
PMID: 26942872
Journal: Oncotarget. 2016 Apr 5;7(14):18424-39.
Title: Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer.
Author: Arienti, Chiara|Zanoni, Michele|Pignatta, Sara|Del Rio, Alberto|Carloni, Silvia|Tebaldi, Michela|Tedaldi, Gianluca|Tesei, Anna
PMID: 26919099
Journal: Expert Opin Biol Ther. 2016;16(2):243-53.
Title: Pertuzumab in gastrointestinal cancer.
Author: Oh, Do-Youn|Bang, Yung-Jue
PMID: 26619359
Journal: J Pathol. 2016 Oct;240(2):137-48.
Title: Comprehensive mutation profiling of mucinous gastric carcinoma.
Author: Rokutan, Hirofumi|Hosoda, Fumie|Hama, Natsuko|Nakamura, Hiromi|Totoki, Yasushi|Furukawa, Eisaku|Arakawa, Erika|Ohashi, Shoko|Urushidate, Tomoko|Satoh, Hironori|Shimizu, Hiroko|Igarashi, Keiko|Yachida, Shinichi|Katai, Hitoshi|Taniguchi, Hirokazu|Fukayama,
PMID: 27313181
Journal: BMC Cancer. 2017 Sep 12;17(1):646.
Title: A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer.
Author: Reynolds, Kerry Lynn|Bedard, Philippe L|Lee, Se-Hoon|Lin, Chia-Chi|Tabernero, Josep|Alsina, Maria|Cohen, Ezra|Baselga, Jose|Blumenschein, George Jr|Graham, Donna M|Garrido-Laguna, Ignacio|Juric, Dejan|Sharma, Sunil|Salgia, Ravi|Seroutou, Abdelkader|Tian,
PMID: 28899363
Journal: BMC Cancer. 2017 Dec 12;17(1):841.
Title: Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients.
Author: Cao, Guo-Dong|Chen, Ke|Chen, Bo|Xiong, Mao-Ming
PMID: 29233126
Journal: Oncotarget. 2017 May 18;8(40):67140-67151.
Title: Prognostic significance of HER3 in patients with malignant solid tumors.
Author: Li, Qin|Zhang, RuiXue|Yan, Han|Zhao, PengFei|Wu, Li|Wang, Hui|Li, Teng|Cao, Bangwei
PMID: 28978022
Journal: Cancer Cell Int. 2017 Sep 13;17:81.
Title: SNP rs3202538 in 3'UTR region of ErbB3 regulated by miR-204 and miR-211 promote gastric cancer development in Chinese population.
Author: Shi, Yaxiang|Chen, Xuan|Xi, Biao|Yu, Xiaowen|Ouyang, Jun|Han, Chunxia|Qin, Yucheng|Wu, Defeng|Shen, Hong
PMID: 28924391
Journal: Oncotarget. 2017 Apr 29;8(32):52584-52593.
Title: siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells.
Author: Yuan, Heng-Heng|Yang, Ying-Nan|Zhou, Jian-Hua|Li, Yan-Jing|Wang, Li-Ying|Qin, Jun-Wei|Liu, Tao|Li, Zhen-Zhen|Zhou, Qing-Xin|Wei, Xiao-Li|Zhang, Ting-Ting|Huang, Peng|Zhang, Wen-Jie|Liu, Lei|Du, Xiao-Xue|Han, Yu
PMID: 28881753
Journal: Gastroenterology. 2017 Aug;153(2):536-549.e26.
Title: Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
Author: Cho, Soo Young|Park, Jun Won|Liu, Yang|Park, Young Soo|Kim, Ju Hee|Yang, Hanna|Um, Hyejin|Ko, Woo Ri|Lee, Byung Il|Kwon, Sun Young|Ryu, Seung Wan|Kwon, Chae Hwa|Park, Do Youn|Lee, Jae-Hyuk|Lee, Sang Il|Song, Kyu Sang|Hur, Hoon|Han, Sang-Uk|Chang, Heekyung
PMID: 28522256
Journal: Pathobiology. 2017;84(4):210-217.
Title: Expression of the ERBB Family of Ligands and Receptors in Gastric Cancer.
Author: Byeon, Sun-Ju|Lee, Hye Seung|Kim, Min-A|Lee, Byung Lan|Kim, Woo Ho
PMID: 28399526
Journal: Cancer Metastasis Rev. 2017 Mar;36(1):141-157.
Title: HER2/HER3 pathway in biliary tract malignancies; systematic review and meta-analysis: a potential therapeutic target?
Author: Galdy, Salvatore|Lamarca, Angela|McNamara, Mairead G|Hubner, Richard A|Cella, Chiara A|Fazio, Nicola|Valle, Juan W
PMID: 27981460
Journal: Cancer Chemother Pharmacol. 2017 Jan;79(1):131-138.
Title: LJM716 in Japanese patients with head and neck squamous cell carcinoma or HER2-overexpressing breast or gastric cancer.
Author: Takahashi, Shunji|Kobayashi, Takayuki|Tomomatsu, Junichi|Ito, Yoshinori|Oda, Hisanobu|Kajitani, Tatsuhiro|Kakizume, Tomoyuki|Tajima, Takeshi|Takeuchi, Hiromi|Maacke, Heiko|Esaki, Taito
PMID: 27942917
Journal: Gastric Cancer. 2018 Mar;21(2):225-236.
Title: Clinical significance of overexpression of NRG1 and its receptors, HER3 and HER4, in gastric cancer patients.
Author: Yun, Sumi|Koh, Jiwon|Nam, Soo Kyung|Park, Jung Ok|Lee, Sung Mi|Lee, Kyoungyul|Lee, Kyu Sang|Ahn, Sang-Hoon|Park, Do Joong|Kim, Hyung-Ho|Choe, Gheeyoung|Kim, Woo Ho|Lee, Hye Seung
PMID: 28573357
Journal: Cell Biol Int. 2018 Jan;42(1):53-62.
Title: 4-Phenybutyric acid promotes gastric cancer cell migration via histone deacetylase inhibition-mediated HER3/HER4 up-regulation.
Author: Shi, Xiaonan|Zheng, Chunlei|Li, Ce|Hou, Kezuo|Wang, Xiaoxun|Yang, Zichang|Liu, Chang|Liu, Yunpeng|Che, Xiaofang|Qu, Xiujuan
PMID: 28851073
Journal: J Clin Pathol. 2018 May;71(5):451-462.
Title: Expression and prognostic significance of human epidermal growth factor receptors 1, 2 and 3 in oesophageal and gastric adenocarcinomas preneoadjuvant and postneoadjuvant treatment.
Author: Hedner, Charlotta|Borg, David|Nodin, Bjorn|Karnevi, Emelie|Jirstrom, Karin|Eberhard, Jakob
PMID: 29138285
Journal: Oncol Lett. 2018 Feb;15(2):1758-1762.
Title: Mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways.
Author: Park, Chul Min|Kawasaki, Yuki|Refaat, Alaa|Sakurai, Hiroaki
PMID: 29434871
Journal: Mol Cancer Ther. 2018 Jun;17(6):1259-1270.
Title: Acquired Resistance to a MET Antibody In Vivo Can Be Overcome by the MET Antibody Mixture Sym015.
Author: Pollmann, Sofie Ellebaek|Calvert, Valerie S|Rao, Shruti|Boca, Simina M|Madhavan, Subha|Horak, Ivan D|Kjaer, Andreas|Petricoin, Emanuel F|Kragh, Michael|Poulsen, Thomas Tuxen
PMID: 29545332
Journal: Ann Surg Oncol. 2018 Jul;25(7):2027-2033.
Title: Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.
Author: van Beek, Elke J A H|Hernandez, Jonathan M|Goldman, Debra A|Davis, Jeremy L|McLaughlin, Kaitlin|Ripley, R Taylor|Kim, Teresa S|Tang, Laura H|Hechtman, Jaclyn F|Zheng, Jian|Capanu, Marinela|Schultz, Nikolaus|Hyman, David M|Ladanyi, Marc|Berger, Michael F|S
PMID: 29725898
Journal: Oncol Lett. 2018 Oct;16(4):4863-4870.
Title: Landscape of somatic mutations in gastric cancer assessed using next-generation sequencing analysis.
Author: Pan, Xuan|Ji, Xiaozhi|Zhang, Renmin|Zhou, Zhaofei|Zhong, Yuejiao|Peng, Wei|Sun, Ning|Xu, Xinyu|Xia, Lei|Li, Pansong|Lu, Jianwei|Tu, Jing
PMID: 30250552