Primary Site >> Colorectal Cancer

Gene >> ERBB3

Journal: Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7792-6.
Title: Differential expression of epidermal growth factor-related proteins in human colorectal tumors.
Author: Ciardiello, F|Kim, N|Saeki, T|Dono, R|Persico, M G|Plowman, G D|Garrigues, J|Radke, S|Todaro, G J|Salomon, D S
PMID: 1715580
Journal: Oncogene. 1995 Nov 16;11(10):2179-84.
Title: Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family.
Author: Mossie, K|Jallal, B|Alves, F|Sures, I|Plowman, G D|Ullrich, A
PMID: 7478540
Journal: Oncogene. 1997 Nov 27;15(22):2705-16.
Title: ErbB kinases and NDF signaling in human prostate cancer cells.
Author: Grasso, A W|Wen, D|Miller, C M|Rhim, J S|Pretlow, T G|Kung, H J
PMID: 9400997
Journal: Hum Pathol. 1998 Aug;29(8):771-7.
Title: Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2.
Author: Maurer, C A|Friess, H|Kretschmann, B|Zimmermann, A|Stauffer, A|Baer, H U|Korc, M|Buchler, M W
PMID: 9712416
Journal: Oncogene. 1999 Jan 14;18(2):305-14.
Title: Regulation of cyclooxygenase-2 pathway by HER2 receptor.
Author: Vadlamudi, R|Mandal, M|Adam, L|Steinbach, G|Mendelsohn, J|Kumar, R
PMID: 9927187
Journal: Semin Oncol. 2001 Oct;28(5 Suppl 16):27-32.
Title: The role of HER2 in angiogenesis.
Author: Kumar, R|Yarmand-Bagheri, R
PMID: 11706393
Journal: Oncogene. 2002 Jan 3;21(1):78-86.
Title: Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
Author: Venkateswarlu, Srinivas|Dawson, Dawn M|St Clair, Patricia|Gupta, Anjana|Willson, James K V|Brattain, Michael G
PMID: 11791178
Journal: Eur J Cancer. 2002 May;38(8):1065-71.
Title: Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery.
Author: Lee, J C|Wang, S-T|Chow, N-H|Yang, H-B
PMID: 12008194
Journal: Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G996-1005. Epub 2003 Feb
Title: Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line.
Author: Cho, Han J|Kim, Woo K|Kim, Eun J|Jung, Kyeong C|Park, Soochul|Lee, Hyun S|Tyner, Angela L|Park, Jung H Y
PMID: 12571082
Journal: Cancer Res. 2004 Apr 1;64(7):2601-9.
Title: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.
Author: Jackson, James G|St Clair, Patricia|Sliwkowski, Mark X|Brattain, Michael G
PMID: 15059917
Journal:
Title: (99m)Tc-Cys-Gly-Gly-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641196
Journal:
Title: (111)In-Benzyl-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-ZHER2:342
Author: Leung, Kam
PMID: 20641264
Journal:
Title: BODIPY-FL-neutravidin-biotin-Cetuximab
Author: Leung, Kam
PMID: 20641313
Journal:
Title: Trastuzumab-manganese-doped iron oxide nanoparticles
Author: Leung, Kam
PMID: 20641351
Journal:
Title: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid- Affibody ZHER2:342-pep2
Author: Leung, Kam
PMID: 20641379
Journal:
Title: Cy5.5-Trastuzumab
Author: Leung, Kam
PMID: 20641392
Journal:
Title: (111)In-Diethylenetriamine pentaacetic acid-pertuzumab
Author: Leung, Kam
PMID: 20641430
Journal:
Title: (111)In-CHX-A"-diethylenepentaacetic acid-Affibody ZHER2:2395-Cys
Author: Leung, Kam
PMID: 20641462
Journal:
Title: Trastuzumab-rhodamine green
Author: Leung, Kam
PMID: 20641468
Journal:
Title: (111)In-CHX-A"-Diethylenetriamine pentaacetic acid-(ZEGFR:955)2
Author: Leung, Kam
PMID: 20641502
Journal:
Title: (111)In-Benzyl-diethylenetriaminepentaacetic acid-ZHER2:342
Author: Leung, Kam
PMID: 20641524
Journal:
Title: [O-(11)C-methyl]4-N-(3-Bromoanilino)-6,7-dimethoxyquinazoline
Author: Leung, Kam
PMID: 20641571
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-cetuximab
Author: Leung, Kam
PMID: 20641633
Journal:
Title: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-Epidermal growth factor
Author: Leung, Kam
PMID: 20641634
Journal:
Title: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-AB.Fab4D5
Author: Leung, Kam
PMID: 20641705
Journal:
Title: Quantum dot-trastuzumab
Author: Leung, Kam
PMID: 20641720
Journal:
Title: (99m)Tc-Affibody ZHER2:2395-Cys
Author: Leung, Kam
PMID: 20641788
Journal:
Title: IRDye 800CW-Epidermal growth factor
Author: Leung, Kam
PMID: 20641801
Journal:
Title: (111)In-BZ-Diethylenetriaminepentaacetic acid-ZEGFR:1907
Author: Leung, Kam
PMID: 20641849
Journal:
Title: (177)Lu-Labeled humanized monoclonal antibody against human epidermal growth factor receptor 2
Author: Chopra, Arvind
PMID: 20641866
Journal:
Title: Cy5.5-Epidermal growth factor
Author: Leung, Kam
PMID: 20641899
Journal:
Title: (111)In-1,4,7,10-tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395-Cys
Author: Leung, Kam
PMID: 20641906
Journal:
Title: (99m)Tc-Mercaptoacetyl-Ser-Ser-Ser-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641924
Journal:
Title: (99m)Tc-Mercaptoacetyl-Gly-Gly-Gly-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641926
Journal:
Title: (99m)Tc-Mercaptoacetyl-Glu-Glu-Glu-Affibody ZHER2:342
Author: Leung, Kam
PMID: 20641930
Journal:
Title: (125)I-Labeled anti-epidermal growth factor receptor human Fab antibody fragment
Author: Leung, Kam
PMID: 20642017
Journal:
Title: Alexa Fluor 750-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 20662137
Journal:
Title: DY-682-Albumin-binding domain-fused-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 20845546
Journal:
Title: IRDye 800-Anti-epidermal growth factor receptor Affibody
Author: Leung, Kam
PMID: 20845547
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-panitumumab
Author: Leung, Kam
PMID: 20945561
Journal:
Title: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-synthetic HER2 specific Affibody ZHER2:342-pep2
Author: Leung, Kam
PMID: 21086574
Journal:
Title: (86)Y-CHX-A''-Diethylenetriamine pentaacetic acid-cetuximab
Author: Leung, Kam
PMID: 21086575
Journal:
Title: Alexa Fluor 750-albumin-binding domain-fused-(ZHER2:342)2 Affibody
Author: Leung, Kam
PMID: 21491705
Journal:
Title: (124)I-Labeled anti-HER2-specific C6.5 diabody
Author: Leung, Kam
PMID: 21834183
Journal:
Title: (86)Y-CHX-A''-diethylenetriamine pentaacetic acid-panitumumab
Author: Leung, Kam
PMID: 22171389
Journal:
Title: (18)F-1,4,7-Triazacyclononane-1,4,7-triacetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395
Author: Leung, Kam
PMID: 22479718
Journal:
Title: (89)Zr-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12
Author: Leung, Kam
PMID: 22696779
Journal:
Title: (68)Ga-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12
Author: Leung, Kam
PMID: 22696780
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu
Author: Leung, Kam
PMID: 22787682
Journal:
Title: (64)Cu-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-(Gly-Ser-Gly) -Lys-Cys-Cys-Tyr-Ser-Leu
Author: Leung, Kam
PMID: 22787683
Journal:
Title: (64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu
Author: Leung, Kam
PMID: 22787684
Journal:
Title: IRDye 800CW-Anti-epidermal growth factor receptor nanobody 7D12
Author: Leung, Kam
PMID: 22787693
Journal:
Title: (99m)Tc(CO)3-Anti-epidermal growth factor receptor nanobody 8B6
Author: Leung, Kam
PMID: 22787694
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-epidermal growth factor receptor-binding fibronectin domain E13.4.3'
Author: Leung, Kam
PMID: 22896860
Journal:
Title: Cy5.5-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 22973578
Journal:
Title: [(111)In-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-10-maleimidoethylacetamide-Cys(61)]-Affibody ZHER2:2395
Author: Leung, Kam
PMID: 22993871
Journal:
Title: (111)In-2-(4,7,10-Tris(carboxymethyl)-1,4,7,10-tetracyclododecan-1-yl)pentanedioi c acid-Trastuzumab
Author: Leung, Kam
PMID: 22993872
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23035309
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidethylacetamide-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23035311
Journal:
Title: QD800-Polyethylene glycol-Cys-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 23101053
Journal:
Title: ZHER2:342 Affibody-polyethylene glycol-superparamagnetic iron oxide nanoparticles
Author: Leung, Kam
PMID: 23101054
Journal:
Title: N-[2-(4-[(18)F]Fluorobenzamido)ethyl]maleimide-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23136679
Journal:
Title: (177)Lu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907
Author: Leung, Kam
PMID: 23166961
Journal:
Title: Cy5.5-8-Amino-octanoic acid-Ser-Cys-Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH2
Author: Leung, Kam
PMID: 23166962
Journal:
Title: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-HER2-specific Affibody ZHER2:2891
Author: Leung, Kam
PMID: 23256220
Journal:
Title: N(epsilon)-(3-[(131)I]Iodobenzoyl)-Lys(5)-N(alpha)-maleimido-Gly(1)-GEEEK-anti-HE R2 nanobody 5F7GGC
Author: Leung, Kam
PMID: 23556153
Journal:
Title: QD800-Anti-epidermal growth factor receptor monoclonal antibody nanoparticles
Author: Leung, Kam
PMID: 23586108
Journal:
Title: IRDye 800-albumin-binding domain-fused-ZHER2:342 Affibody
Author: Leung, Kam
PMID: 23785735
Journal: J Cancer Res Clin Oncol. 2005 Jan;131(1):49-59.
Title: Listeria monocytogenes produces a pro-invasive factor that signals via ErbB2/ErbB3 heterodimers.
Author: Oliveira, Maria Jose|Lauwaet, Tineke|De Bruyne, Georges|Mareel, Marc|Leroy, Ancy
PMID: 15480783
Journal: Mol Cancer Ther. 2005 Feb;4(2):243-55.
Title: H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
Author: Caron, Ruben W|Yacoub, Adly|Zhu, Xiaoyu|Mitchell, Clint|Han, Song Iy|Sasazuki, Takehiko|Shirasawa, Senji|Hagan, Michael P|Grant, Steven|Dent, Paul
PMID: 15713896
Journal: J Nutr Biochem. 2005 Mar;16(3):155-62.
Title: Quercetin decreases the expression of ErbB2 and ErbB3 proteins in HT-29 human colon cancer cells.
Author: Kim, Woo K|Bang, Myung H|Kim, Eul S|Kang, Nam E|Jung, Kyeong C|Cho, Han J|Park, Jung H Y
PMID: 15741050
Journal: Cancer Chemother Pharmacol. 2005 Aug;56(2):126-37.
Title: Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
Author: Smith, Victoria|Sausville, Edward A|Camalier, Richard F|Fiebig, Heinz-Herbert|Burger, Angelika M
PMID: 15841378
Journal: J Biol Chem. 2005 Jul 22;280(29):27383-92. Epub 2005 May 11.
Title: Reorganization of ErbB family and cell survival signaling after Knock-down of ErbB2 in colon cancer cells.
Author: Hu, Yi Peter|Venkateswarlu, Srinivas|Sergina, Natalia|Howell, Gillian|St Clair, Patricia|Humphrey, Lisa E|Li, Wenhui|Hauser, Jennie|Zborowska, Elizabeth|Willson, James K V|Brattain, Michael G
PMID: 15888451
Journal: Cancer Res. 2005 May 15;65(10):4253-60.
Title: HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.
Author: Hirata, Akira|Hosoi, Fumihito|Miyagawa, Miho|Ueda, Shu-ichi|Naito, Seiji|Fujii, Teruhiko|Kuwano, Michihiko|Ono, Mayumi
PMID: 15899817
Journal: Mol Pharmacol. 2005 Aug;68(2):502-10. Epub 2005 May 20.
Title: Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.
Author: Janmaat, Maarten L|Rodriguez, Jose A|Jimeno, Jose|Kruyt, Frank A E|Giaccone, Giuseppe
PMID: 15908515
Journal: Biochem Biophys Res Commun. 2005 Sep 2;334(3):947-53.
Title: EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.
Author: Shimizu, Masahito|Deguchi, Atsuko|Hara, Yukihiko|Moriwaki, Hisataka|Weinstein, I Bernard
PMID: 16053920
Journal: World J Gastroenterol. 2005 Sep 7;11(33):5142-50.
Title: Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid decreases ErbB3 expression in HT-29 human colon cancer cells.
Author: Cho, Han Jin|Kim, Woo Kyoung|Jung, Jae In|Kim, Eun Ji|Lim, Soon Sung|Kwon, Dae Young|Park, Jung Han Yoon
PMID: 16127743
Journal: J Med Food. 2005 Winter;8(4):431-8.
Title: Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein.
Author: Kim, Eun Ji|Shin, Hyun-Kyung|Park, Jung Han Yoon
PMID: 16379552
Journal: J Exp Ther Oncol. 2005;5(1):69-78.
Title: EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
Author: Shimizu, Masahito|Deguchi, Atsuko|Joe, Andrew K|Mckoy, Judith F|Moriwaki, Hisataka|Weinstein, I Bernard
PMID: 16416603
Journal: Int J Cancer. 2006 Mar 15;118(6):1426-9.
Title: Somatic mutations of the ERBB4 kinase domain in human cancers.
Author: Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Wang, Young Pil|Jo, Keon Hyun|Moon, Seok Whan|Park, Won Sang|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 16187281
Journal: BMC Cancer. 2006 Feb 28;6:46.
Title: Prognostic significance of HER3 and HER4 protein expression in colorectal adenocarcinomas.
Author: Kountourakis, Panteleimon|Pavlakis, Kitty|Psyrri, Amanda|Rontogianni, Dimitra|Xiros, Nikolaos|Patsouris, Efstratios|Pectasides, Dimitrios|Economopoulos, Theofanis
PMID: 16507107
Journal: DNA Cell Biol. 2006 Jul;25(7):399-405.
Title: Mutation of the PI3' kinase gene in a human colon carcinoma cell line, HCC2998.
Author: Shi, Bin-Hi|Nashimoto, Takeshi|Andoh, Ryota|Konishi, Hiroaki|Kobayashi, Michimoto|Xu, Qingyun|Ihara, Sayoko|Fukui, Yasuhisa
PMID: 16848681
Journal: Clin Cancer Res. 2006 Dec 15;12(24):7222-31.
Title: Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway.
Author: Rosell, Rafael|Taron, Miquel|Reguart, Noemi|Isla, Dolores|Moran, Teresa
PMID: 17189393
Journal: Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16478-83.
Title: Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells.
Author: Baldwin, Amy|Li, Wenliang|Grace, Miranda|Pearlberg, Joseph|Harlow, Ed|Munger, Karl|Grueneberg, Dorre A
PMID: 18948598
Journal: Anticancer Res. 2009 Jan;29(1):229-34.
Title: Expression of ErbB receptors and their cognate ligands in gastric and colon cancer cell lines.
Author: Wu, William Ka Kei|Tse, Timothy Tim Ming|Sung, Joseph Jao Yiu|Li, Zhi Jie|Yu, Le|Cho, Chi Hin
PMID: 19331154
Journal: BMC Mol Biol. 2009 Apr 15;10:31.
Title: Reverse transcription-quantitative polymerase chain reaction: description of a RIN-based algorithm for accurate data normalization.
Author: Ho-Pun-Cheung, Alexandre|Bascoul-Mollevi, Caroline|Assenat, Eric|Boissiere-Michot, Florence|Bibeau, Frederic|Cellier, Dominic|Ychou, Marc|Lopez-Crapez, Evelyne
PMID: 19368728
Journal: Int J Colorectal Dis. 2009 Sep;24(9):1059-68.
Title: ErbB family immunohistochemical expression in colorectal cancer patients with higher risk of recurrence after radical surgery.
Author: Baiocchi, Glauco|Lopes, Ademar|Coudry, Renata A|Rossi, Benedito M|Soares, Fernando A|Aguiar, Samuel|Guimaraes, Gustavo C|Ferreira, Fabio O|Nakagawa, Wilson T
PMID: 19390858
Journal: Anticancer Res. 2009 May;29(5):1489-94.
Title: ErbB 1-4 expression alterations in primary colorectal cancers and their corresponding metastases.
Author: Ljuslinder, Ingrid|Malmer, Beatrice|Isaksson-Mettavainio, Martin|Oberg, Ake|Henriksson, Roger|Stenling, Roger|Palmqvist, Richard
PMID: 19443355
Journal: J Clin Invest. 2009 Sep;119(9):2702-13.
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Author: Lee, Daekee|Yu, Ming|Lee, Eunjung|Kim, Hyunok|Yang, Yanan|Kim, Kyoungmi|Pannicia, Christina|Kurie, Jonathan M|Threadgill, David W
PMID: 19690388
Journal: Digestion. 2009;80(4):215-25.
Title: Heregulin-induced VEGF expression via the ErbB3 signaling pathway in colon cancer.
Author: Yonezawa, Masaoki|Wada, Ken|Tatsuguchi, Atsushi|Akamatsu, Tomonori|Gudis, Katya|Seo, Tsuguhiko|Mitsui, Keigo|Nagata, Kazuhiro|Tanaka, Shu|Fujimori, Shunji|Sakamoto, Choitsu
PMID: 19797898
Journal: Clin Cancer Res. 2009 Dec 15;15(24):7529-7537.
Title: Vascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant {beta}-Catenin Activation in Colon Cancer.
Author: Naik, Snehal|Dothager, Robin S|Marasa, Jayne|Lewis, Cory L|Piwnica-Worms, David
PMID: 20008853
Journal: PLoS Comput Biol. 2009 Dec;5(12):e1000601.
Title: Human cancer protein-protein interaction network: a structural perspective.
Author: Kar, Gozde|Gursoy, Attila|Keskin, Ozlem
PMID: 20011507
Journal: Int J Cancer. 2010 Aug 15;127(4):780-90.
Title: The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition.
Author: Ma, Elise L|Choi, Yoon Jeong|Choi, Jinyoung|Pothoulakis, Charalabos|Rhee, Sang Hoon|Im, Eunok
PMID: 19876926
Journal: Cancer Lett. 2010 Jul 1;293(1):23-30.
Title: Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.
Author: Choi, Sujin|Choi, Yunjin|Dat, Nguyen Tien|Hwangbo, Cheol|Lee, Jung Joon|Lee, Jeong-Hyung
PMID: 20056314
Journal: Exp Cell Res. 2010 Apr 15;316(7):1083-100.
Title: Mechanisms of resistance to HER family targeting antibodies.
Author: Kruser, Tim J|Wheeler, Deric L
PMID: 20064507
Journal: Cancer Sci. 2010 Sep;101(9):2011-8.
Title: Significance of integrin alphavbeta5 and erbB3 in enhanced cell migration and liver metastasis of colon carcinomas stimulated by hepatocyte-derived heregulin.
Author: Yoshioka, Toshiaki|Nishikawa, Yuji|Ito, Reiko|Kawamata, Makiko|Doi, Yuko|Yamamoto, Yohei|Yoshida, Masayuki|Omori, Yasufumi|Kotanagi, Hitoshi|Masuko, Takashi|Enomoto, Katsuhiko
PMID: 20626753
Journal: Cancer Biomark. 2010-2011;8(2):61-5.
Title: The EGFR R521K polymorphism influences the risk to develop colorectal cancer.
Author: Martinelli, Marcella|Ugolini, Giampaolo|Scapoli, Luca|Rivetti, Stefano|Lauriola, Mattia|Mattei, Gabriella|Rosati, Giancarlo|Montroni, Isacco|Manaresi, Alessio|Zattoni, Davide|Taffurelli, Mario|Solmi, Rossella
PMID: 21896992
Journal: Int J Cancer. 2011 Jun 15;128(12):2938-46.
Title: EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer.
Author: Ho-Pun-Cheung, Alexandre|Assenat, Eric|Bascoul-Mollevi, Caroline|Bibeau, Frederic|Boissiere-Michot, Florence|Cellier, Dominic|Azria, David|Rouanet, Philippe|Senesse, Pierre|Ychou, Marc|Lopez-Crapez, Evelyne
PMID: 20824716
Journal: Clin Cancer Res. 2011 Feb 1;17(3):472-82.
Title: HGF rescues colorectal cancer cells from EGFR inhibition via MET activation.
Author: Liska, David|Chen, Chin-Tung|Bachleitner-Hofmann, Thomas|Christensen, James G|Weiser, Martin R
PMID: 21098338
Journal: Oncol Rep. 2011 Jan;25(1):3-11.
Title: EGFR, HER2 and HER3 expression in primary colorectal carcinomas and corresponding metastases: Implications for targeted radionuclide therapy.
Author: Wei, Q|Shui, Y|Zheng, S|Wester, K|Nordgren, H|Nygren, P|Glimelius, B|Carlsson, J
PMID: 21109951
Journal: Sci Transl Med. 2011 Sep 7;3(99):99ra86.
Title: Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.
Author: Yonesaka, Kimio|Zejnullahu, Kreshnik|Okamoto, Isamu|Satoh, Taroh|Cappuzzo, Federico|Souglakos, John|Ercan, Dalia|Rogers, Andrew|Roncalli, Massimo|Takeda, Masayuki|Fujisaka, Yasuhito|Philips, Juliet|Shimizu, Toshio|Maenishi, Osamu|Cho, Yonggon|Sun, Jason|D
PMID: 21900593
Journal: Clin Cancer Res. 2012 Feb 15;18(4):956-68.
Title: Toward the prognostic significance and therapeutic potential of HER3 receptor tyrosine kinase in human colon cancer.
Author: Beji, Abdelhamid|Horst, David|Engel, Jutta|Kirchner, Thomas|Ullrich, Axel
PMID: 22142822
Journal: Clin Cancer Res. 2012 Feb 15;18(4):917-9.
Title: Increasing potential of HER3 signaling in colon cancer progression and therapy.
Author: Gespach, Christian
PMID: 22205688
Journal: Int J Oncol. 2012 Jul;41(1):317-24.
Title: ErbB3 expression predicts sensitivity to elisidepsin treatment: in vitro synergism with cisplatin, paclitaxel and gemcitabine in lung, breast and colon cancer cell lines.
Author: Teixido, Cristina|Arguelaguet, Elisabet|Pons, Berta|Aracil, Miguel|Jimeno, Jose|Somoza, Rosa|Mares, Roso|Ramon Y Cajal, Santiago|Hernandez-Losa, Javier
PMID: 22485250
Journal: Biomark Med. 2012 Apr;6(2):200.
Title: HER3: a potential marker in colon cancer.
Author: Neagu, Monica|Albulescu, Radu|Tanase, Cristiana
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Title: Irinotecan resistance is accompanied by upregulation of EGFR and Src signaling in human cancer models.
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Title: HER3 overexpression and survival in solid tumors: a meta-analysis.
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Title: Involvement of heregulin/HER3 in the primary culture of human urothelial cancer.
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Title: Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers.
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Title: Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation.
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Title: Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.
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Title: The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab.
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Title: Multigene assays in metastatic colorectal cancer.
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Title: Proliferation of colorectal cancer is promoted by two signaling transduction expression patterns: ErbB2/ErbB3/AKT and MET/ErbB3/MAPK.
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Title: Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients.
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Title: The ErbB/HER family of protein-tyrosine kinases and cancer.
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Title: HER3 expression in patients with primary colorectal cancer and corresponding lymph node metastases related to clinical outcome.
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Title: Imaging of HER3-expressing xenografts in mice using a (99m)Tc(CO) 3-HEHEHE-Z HER3:08699 affibody molecule.
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Title: ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models.
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Journal: Cell Rep. 2014 Apr 10;7(1):86-93.
Title: Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.
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Title: Nrdp1 inhibits growth of colorectal cancer cells by nuclear retention of p27.
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Title: Mutational and expressional analysis of ERBB3 gene in common solid cancers.
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Title: ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.
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Journal: PLoS One. 2014 Aug 4;9(8):e103551.
Title: Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independent of KRAS mutational status.
Author: Lee, Jeeyun|Jain, Anjali|Kim, Phillip|Lee, Tani|Kuller, Anne|Princen, Fred|In-GuDo|Kim, Suk Hyeong|Park, Joon Oh|Park, Young Suk|Singh, Sharat|Kim, Hee Cheol
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Journal: J Cancer Prev. 2014 Sep;19(3):161-9.
Title: Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells.
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Journal: Sci Signal. 2014 Nov 11;7(351):ra107.
Title: Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Author: Belmont, Peter J|Jiang, Ping|McKee, Trevor D|Xie, Tao|Isaacson, Jason|Baryla, Nicole E|Roper, Jatin|Sinnamon, Mark J|Lee, Nathan V|Kan, Julie L C|Guicherit, Oivin|Wouters, Bradly G|O'Brien, Catherine A|Shields, David|Olson, Peter|VanArsdale, Todd|Weinrich
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Journal: BMC Cancer. 2014 Nov 22;14:863.
Title: Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer.
Author: Mitsui, Keigo|Yonezawa, Masaoki|Tatsuguchi, Atsushi|Shinji, Seiichi|Gudis, Katya|Tanaka, Shu|Fujimori, Shunji|Sakamoto, Choitsu
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Journal: Oncotarget. 2014 Dec 15;5(23):11847-56.
Title: The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells.
Author: Kawakami, Hisato|Okamoto, Isamu|Yonesaka, Kimio|Okamoto, Kunio|Shibata, Kiyoko|Shinkai, Yume|Sakamoto, Haruka|Kitano, Michiko|Tamura, Takao|Nishio, Kazuto|Nakagawa, Kazuhiko
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Journal: Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):839-44.
Title: Examination of HER3 targeting in cancer using monoclonal antibodies.
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PMID: 25564668
Journal: Acta Oncol. 2015 Apr;54(4):480-6.
Title: HER3 expression in primary colorectal cancer including corresponding metastases in lymph node and liver.
Author: Ledel, Frida|Stenstedt, Kristina|Hallstrom, Marja|Ragnhammar, Peter|Edler, David
PMID: 25601452
Journal: Virchows Arch. 2015 Jun;466(6):645-54.
Title: HER3 protein expression in relation to HER2 positivity in patients with primary colorectal cancer: clinical relevance and prognostic value.
Author: Seo, An Na|Kwak, Yoonjin|Kim, Woo Ho|Kim, Duck-Woo|Kang, Sung-Bum|Choe, Gheeyoung|Lee, Hye Seung
PMID: 25739551
Journal: Ann Biol Clin (Paris). 2015 Mar-Apr;73(2):158-64.
Title: [Accumulation of p53 protein and overexpression of the HER3 receptor in colorectal cancer].
Author: Amsaguine, Siham|El Mhaia, Sara|Drissi, Houda|Amer, Chrifa|Ahallat, Mohammed|El Amrani, Najat|Radallah, Driss
PMID: 25847737
Journal: Am Soc Clin Oncol Educ Book. 2015:e149-56.
Title: Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer.
Author: Dienstmann, Rodrigo|Salazar, Ramon|Tabernero, Josep
PMID: 25993166
Journal: Clin Cancer Res. 2015 Jun 1;21(11):2462-70.
Title: Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors.
Author: Juric, Dejan|Dienstmann, Rodrigo|Cervantes, Andres|Hidalgo, Manuel|Messersmith, Wells|Blumenschein, George R Jr|Tabernero, Josep|Roda, Desamparados|Calles, Antonio|Jimeno, Antonio|Wang, Xiaodong|Bohorquez, Sandra Sanabria|Leddy, Cecilia|Littman, Catherine
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Journal: Int J Mol Sci. 2015 Aug 17;16(8):19447-57.
Title: Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma.
Author: Gonzalez-Alonso, Paula|Chamizo, Cristina|Moreno, Victor|Madoz-Gurpide, Juan|Carvajal, Nerea|Daoud, Lina|Zazo, Sandra|Martin-Aparicio, Ester|Cristobal, Ion|Rincon, Raul|Garcia-Foncillas, Jesus|Rojo, Federico
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Journal: PLoS One. 2015 Sep 14;10(9):e0138336.
Title: ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer.
Author: Jarde, Thierry|Kass, Lisa|Staples, Margaret|Lescesen, Helen|Carne, Peter|Oliva, Karen|McMurrick, Paul J|Abud, Helen E
PMID: 26367378
Journal: J Exp Clin Cancer Res. 2015 Oct 1;34:108.
Title: Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer.
Author: Giordano, Guido|Febbraro, Antonio|Tomaselli, Eugenio|Sarnicola, Maria Lucia|Parcesepe, Pietro|Parente, Domenico|Forte, Nicola|Fabozzi, Alessio|Remo, Andrea|Bonetti, Andrea|Manfrin, Erminia|Ghasemi, Somayehsadat|Ceccarelli, Michele|Cerulo, Luigi|Bazzoni, F
PMID: 26427914
Journal: PLoS One. 2015 Nov 16;10(11):e0143132.
Title: Combined Analysis of Plasma Amphiregulin and Heregulin Predicts Response to Cetuximab in Metastatic Colorectal Cancer.
Author: Yonesaka, Kimio|Takegawa, Naoki|Satoh, Taroh|Ueda, Hiroto|Yoshida, Takeshi|Takeda, Masayuki|Shimizu, Toshio|Chiba, Yasutaka|Okamoto, Isamu|Nishio, Kazuto|Tamura, Takao|Nakagawa, Kazuhiko
PMID: 26569500
Journal: PLoS One. 2015 Nov 16;10(11):e0143076.
Title: Immuno-PET Imaging of HER3 in a Model in which HER3 Signaling Plays a Critical Role.
Author: Yuan, Qinghua|Furukawa, Takako|Tashiro, Takahiro|Okita, Kouki|Jin, Zhao-Hui|Aung, Winn|Sugyo, Aya|Nagatsu, Kotaro|Endo, Hiroko|Tsuji, Atsushi B|Zhang, Ming-Rong|Masuko, Takashi|Inoue, Masahiro|Fujibayashi, Yasuhisa|Saga, Tsuneo
PMID: 26571416
Journal: Expert Opin Biol Ther. 2016;16(2):243-53.
Title: Pertuzumab in gastrointestinal cancer.
Author: Oh, Do-Youn|Bang, Yung-Jue
PMID: 26619359
Journal: Acta Oncol. 2016 Jul;55(7):875-80.
Title: HER3 expression is correlated to distally located and low-grade colon cancer.
Author: Ledel, Frida|Stenstedt, Kristina|Hallstrom, Marja|Ragnhammar, Peter|Edler, David
PMID: 26863446
Journal: Mol Med Rep. 2016 Apr;13(4):3514-20.
Title: Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer.
Author: Nagaoka, Tomoko|Kitaura, Kazutaka|Miyata, Yukinaga|Kumagai, Kenichi|Kaneda, Goro|Kanazawa, Hideki|Suzuki, Satsuki|Hamada, Yoshiki|Suzuki, Ryuji
PMID: 26935861
Journal: Crit Rev Oncol Hematol. 2016 May;101:151-7.
Title: Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance.
Author: Temraz, Sally|Mukherji, Deborah|Shamseddine, Ali
PMID: 27017409
Journal: Oncotarget. 2016 Aug 16;7(33):53526-53539.
Title: Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling.
Author: Moller, Yvonne|Morkel, Markus|Schmid, Jens|Beyes, Sven|Hendrick, Janina|Strotbek, Michaela|Riemer, Pamela|Schmid, Simone|Schmitt, Lisa C|Kontermann, Roland|Murdter, Thomas|Schwab, Matthias|Sers, Christine|Olayioye, Monilola A
PMID: 27447549
Journal: Cancer Med. 2016 Sep;5(9):2249-60.
Title: Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance).
Author: Hatch, Ace J|Sibley, Alexander B|Starr, Mark D|Brady, J Chris|Jiang, Chen|Jia, Jingquan|Bowers, Daniel L|Pang, Herbert|Owzar, Kouros|Niedzwiecki, Donna|Innocenti, Federico|Venook, Alan P|Hurwitz, Herbert I|Nixon, Andrew B
PMID: 27465221
Journal: Gastroenterol Res Pract. 2016;2016:3481578.
Title: Prognostic Impact of mRNA Expression Levels of HER1-4 (ERBB1-4) in Patients with Locally Advanced Rectal Cancer.
Author: Kripp, Melanie|Merx, Kirsten|Wirtz, Ralph Markus|Gaiser, Timo|Eidt, Sebastian|Schwaab, Juliana|Post, Stefan|Wenz, Frederik|Hochhaus, Andreas|Hofheinz, Ralf-Dieter|Erben, Philipp
PMID: 27610130
Journal: Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title: Genomic characterization of liver metastases from colorectal cancer patients.
Author: Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant
PMID: 27662660
Journal: Cell Oncol (Dordr). 2016 Dec;39(6):545-558.
Title: DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up.
Author: Bigagli, Elisabetta|De Filippo, Carlotta|Castagnini, Cinzia|Toti, Simona|Acquadro, Francesco|Giudici, Francesco|Fazi, Marilena|Dolara, Piero|Messerini, Luca|Tonelli, Francesco|Luceri, Cristina
PMID: 27709558
Journal: Expert Opin Biol Ther. 2016 Dec;16(12):1549-1555.
Title: The prospect of patritumab for treating non-small cell lung cancer.
Author: Horinouchi, Hidehito
PMID: 27744717
Journal: Eur Rev Med Pharmacol Sci. 2016 Nov;20(22):4682-4687.
Title: Down-regulation of microRNA-143 is associated with colorectal cancer progression.
Author: Bai, J-W|Xue, H-Z|Zhang, C
PMID: 27906435
Journal: Curr Oncol. 2016 Dec;23(6):e571-e575.
Title: Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Author: Sheffield, B S|Tessier-Cloutier, B|Li-Chang, H|Shen, Y|Pleasance, E|Kasaian, K|Li, Y|Jones, S J M|Lim, H J|Renouf, D J|Huntsman, D G|Yip, S|Laskin, J|Marra, M|Schaeffer, D F
PMID: 28050146
Journal: Mol Carcinog. 2017 Mar;56(3):1068-1081.
Title: KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation.
Author: Sun, Eun Gene|Lee, Kyung Hwa|Ko, Yoo-Seung|Choi, Hui Jeong|Yang, Jung-In|Lee, Jae Hyuk|Chung, Ik Joo|Paek, Yun-Woong|Kim, Hangun|Bae, Jeong A|Kim, Kyung Keun
PMID: 27648936
Journal: Invest New Drugs. 2017 Feb;35(1):68-78.
Title: A phase 1 study combining the HER3 antibody seribantumab (MM-121) and cetuximab with and without irinotecan.
Author: Cleary, James M|McRee, Autumn J|Shapiro, Geoffrey I|Tolaney, Sara M|O'Neil, Bert H|Kearns, Jeffrey D|Mathews, Sara|Nering, Rachel|MacBeath, Gavin|Czibere, Akos|Sharma, Sunil|Korn, W Michael
PMID: 27853996
Journal: Oncotarget. 2017 Jan 17;8(3):4277-4288.
Title: Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Author: Bosch-Vilaro, Albert|Jacobs, Bart|Pomella, Valentina|Abbasi Asbagh, Layka|Kirkland, Richard|Michel, Joe|Singh, Sharat|Liu, Xinjun|Kim, Phillip|Weitsman, Gregory|Barber, Paul R|Vojnovic, Borivoj|Ng, Tony|Tejpar, Sabine
PMID: 28032592
Journal: Oncoimmunology. 2016 Dec 7;6(1):e1255395.
Title: Prophylactic vaccination targeting ERBB3 decreases polyp burden in a mouse model of human colorectal cancer.
Author: Bautz, David J|Sherpa, Ang T|Threadgill, David W
PMID: 28197371
Journal: Expert Opin Ther Pat. 2017 May;27(5):527-538.
Title: Methods of selecting combination therapy for colorectal cancer patients: a patent evaluation of US20160025730A1.
Author: Plano, Daniel|Alcolea, Veronica|Sanmartin, Carmen|Sharma, Arun K
PMID: 28366103
Journal: Cancer Discov. 2017 Jun;7(6):OF12.
Title: Profiling Differential Responses to Pan-HER Inhibition.
Author:
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Journal: Oncotarget. 2017 May 18;8(40):67140-67151.
Title: Prognostic significance of HER3 in patients with malignant solid tumors.
Author: Li, Qin|Zhang, RuiXue|Yan, Han|Zhao, PengFei|Wu, Li|Wang, Hui|Li, Teng|Cao, Bangwei
PMID: 28978022
Journal: Oncotarget. 2017 Jul 10;8(40):68026-68037.
Title: Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.
Author: Kong, Say Li|Liu, Xingliang|Suhaimi, Nur-Afidah Mohamed|Koh, Kenneth Jia Hao|Hu, Min|Lee, Daniel Yoke San|Cima, Igor|Phyo, Wai Min|Lee, Esther Xing Wei|Tai, Joyce A|Foong, Yu Miin|Vo, Jess Honganh|Koh, Poh Koon|Zhang, Tong|Ying, Jackie Y|Lim, Bing|Tan, Mi
PMID: 28978093
Journal: Br J Cancer. 2017 Dec 5;117(12):1819-1827.
Title: Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.
Author: Lievre, Astrid|Ouine, Berengere|Canet, Jim|Cartier, Aurelie|Amar, Yael|Cacheux, Wulfran|Mariani, Odette|Guimbaud, Rosine|Selves, Janick|Lecomte, Thierry|Guyetant, Serge|Bieche, Ivan|Berger, Frederique|de Koning, Leanne
PMID: 29024937
Journal: Int J Oncol. 2017 Dec;51(6):1765-1774.
Title: Evaluation of a radiocobalt-labelled affibody molecule for imaging of human epidermal growth factor receptor 3 expression.
Author: Rosestedt, Maria|Andersson, Ken G|Mitran, Bogdan|Rinne, Sara S|Tolmachev, Vladimir|Lofblom, John|Orlova, Anna|Stahl, Stefan
PMID: 29039474
Journal: Oncotarget. 2017 Jun 13;8(51):89284-89306.
Title: A comprehensive review of heregulins, HER3, and HER4 as potential therapeutic targets in cancer.
Author: Mota, Jose Mauricio|Collier, Katharine Ann|Barros Costa, Ricardo Lima|Taxter, Timothy|Kalyan, Aparna|Leite, Caio A|Chae, Young Kwang|Giles, Francis J|Carneiro, Benedito A
PMID: 29179520
Journal: Oncotarget. 2016 Aug 19;8(65):108463-108479.
Title: Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers.
Author: Bon, Giulia|Loria, Rossella|Amoreo, Carla Azzurra|Verdina, Alessandra|Sperduti, Isabella|Mastrofrancesco, Arianna|Soddu, Silvia|Diodoro, Maria Grazia|Mottolese, Marcella|Todaro, Matilde|Stassi, Giorgio|Milella, Michele|De Maria, Ruggero|Falcioni, Rita
PMID: 29312543
Journal: JAMA Oncol. 2018 Apr 1;4(4):564-568.
Title: Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer.
Author: Seligmann, Jenny F|Hatch, Ace J|Richman, Susan D|Elliott, Faye|Jacobs, Bart|Brown, Sarah|Hurwitz, Herbert|Barrett, Jennifer H|Quirke, Philip|Nixon, Andrew B|Seymour, Matthew T
PMID: 29075780
Journal: Lancet Gastroenterol Hepatol. 2018 Mar;3(3):162-171.
Title: Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2-3 randomised trial.
Author: Adams, Richard|Brown, Ewan|Brown, Louise|Butler, Rachel|Falk, Stephen|Fisher, David|Kaplan, Richard|Quirke, Phil|Richman, Susan|Samuel, Leslie|Seligmann, Jenny|Seymour, Matt|Shiu, Kai Keen|Wasan, Harpreet|Wilson, Richard|Maughan, Tim
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Journal: Oncogene. 2018 Mar;37(12):1576-1593.
Title: BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.
Author: Herr, Ricarda|Halbach, Sebastian|Heizmann, Miriam|Busch, Hauke|Boerries, Melanie|Brummer, Tilman
PMID: 29326440
Journal: Cancer. 2018 Apr 1;124(7):1358-1373.
Title: Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.
Author: Ross, Jeffrey S|Fakih, Marwan|Ali, Siraj M|Elvin, Julia A|Schrock, Alexa B|Suh, James|Vergilio, Jo-Anne|Ramkissoon, Shakti|Severson, Eric|Daniel, Sugganth|Fabrizio, David|Frampton, Garrett|Sun, James|Miller, Vincent A|Stephens, Philip J|Gay, Laurie M
PMID: 29338072
Journal: Cancer Res Treat. 2018 Jan 17. pii: crt.2017.487.
Title: Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer.
Author: Yun, Sumi|Kwak, Yoonjin|Nam, Soo Kyung|Seo, An Na|Oh, Heung-Kwon|Kim, Duck-Woo|Kang, Sung-Bum|Lee, Hye Seung
PMID: 29361822
Journal: Eur J Cancer. 2018 Mar;92:1-10.
Title: Human epidermal receptor family inhibitors in patients with ERBB3 mutated cancers: Entering the back door.
Author: Verlingue, Loic|Hollebecque, Antoine|Lacroix, Ludovic|Postel-Vinay, Sophie|Varga, Andrea|El Dakdouki, Yolla|Baldini, Capucine|Balheda, Rastilav|Gazzah, Anas|Michot, Jean-Marie|Marabelle, Aurelien|Mir, Olivier|Arnedos, Monica|Rouleau, Etienne|Solary, Eric|
PMID: 29413684
Journal: Sci Rep. 2018 Feb 16;8(1):3161.
Title: Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations.
Author: Druliner, Brooke R|Wang, Panwen|Bae, Taejeong|Baheti, Saurabh|Slettedahl, Seth|Mahoney, Douglas|Vasmatzis, Nikolaos|Xu, Hang|Kim, Minsoo|Bockol, Matthew|O'Brien, Daniel|Grill, Diane|Warner, Nathaniel|Munoz-Gomez, Miguel|Kossick, Kimberlee|Johnson, Ruth|Mo
PMID: 29453410
Journal: Oncotarget. 2018 Jan 31;9(13):11322-11335.
Title: Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells.
Author: Hutt, Meike|Fellermeier-Kopf, Sina|Seifert, Oliver|Schmitt, Lisa C|Pfizenmaier, Klaus|Kontermann, Roland E
PMID: 29541416
Journal: Oncotarget. 2018 Mar 23;9(22):15968-15983.
Title: Promotion of malignant phenotype after disruption of the three-dimensional structure of cultured spheroids from colorectal cancer.
Author: Piulats, Jose M|Kondo, Jumpei|Endo, Hiroko|Ono, Hiromasa|Hagihara, Takeshi|Okuyama, Hiroaki|Nishizawa, Yasuko|Tomita, Yasuhiko|Ohue, Masayuki|Okita, Kouki|Oyama, Hidejiro|Bono, Hidemasa|Masuko, Takashi|Inoue, Masahiro
PMID: 29662620
Journal: J Natl Cancer Inst. 2018 Apr 27. pii: 4989438.
Title: Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Author: Loree, Jonathan M|Bailey, Ann M|Johnson, Amber M|Yu, Yao|Wu, Wenhui|Bristow, Christopher A|Davis, Jennifer S|Shaw, Kenna R|Broaddus, Russell|Banks, Kimberly C|Lanman, Richard B|Meric-Bernstam, Funda|Overman, Michael J|Kopetz, Scott|Raghav, Kanwal
PMID: 29718453
Journal: Oncol Lett. 2018 Jul;16(1):326-334.
Title: Cetuximab improves AZD6244 antitumor activity in colorectal cancer HT29 cells in vitro and in nude mice by attenuating HER3/Akt pathway activation.
Author: Zhang, Qin|Xiao, He|Jin, Feng|Li, Mengxia|Luo, Jia|Wang, Ge
PMID: 29928418
Journal: Oncol Lett. 2018 Aug;16(2):1863-1868.
Title: Aneuploidy of chromosome 8 and mutation of circulating tumor cells predict pathologic complete response in the treatment of locally advanced rectal cancer.
Author: Wan, Jue-Feng|Li, Xue-Qin|Zhang, Jing|Yang, Li-Feng|Zhu, Ji|Li, Gui-Chao|Liang, Li-Ping|Shen, Li-Jun|Zhang, Hui|Li, Jing|Zhang, Yi-Tong|Chen, Chang-Yue|Zhang, Zhen
PMID: 30008877
Journal: Mol Cancer Res. 2018 Aug 21. pii: 1541-7786.MCR-18-0341.
Title: Endothelial Cells Promote Colorectal Cancer Cell Survival by Activating the HER3-AKT Pathway in a Paracrine Fashion.
Author: Wang, Rui|Bhattacharya, Rajat|Ye, Xiangcang|Fan, Fan|Boulbes, Delphine R|Ellis, Lee M
PMID: 30131447
Journal: Medicine (Baltimore). 2018 Sep;97(37):e12317.
Title: Association between the overexpression of Her3 and clinical pathology and prognosis of colorectal cancer: A meta-analysis.
Author: Yan, Qingying|Guo, Kaibo|Feng, Guan|Shan, Feiyu|Sun, Leitao|Zhang, Kai|Shen, Fengfei|Shen, Minhe|Ruan, Shanming
PMID: 30212974