Primary Site >> Pancreatic Cancer

Gene >> ERBB2

Journal: J Pathol. 1990 Jul;161(3):195-200.
Title: The c-erb B-2 proto-oncogene in human pancreatic cancer.
Author: Hall, P A|Hughes, C M|Staddon, S L|Richman, P I|Gullick, W J|Lemoine, N R
PMID: 2202801
Journal: Pathobiology. 1991;59(1):46-52.
Title: Expression of c-erbB-2 in human pancreatic adenocarcinomas.
Author: Williams, T M|Weiner, D B|Greene, M I|Maguire, H C Jr
PMID: 1675057
Journal: Nihon Ika Daigaku Zasshi. 1992 Feb;59(1):51-61.
Title: The immunohistochemical expressions of epidermal growth factors, epidermal growth factor receptors and c-erbB-2 oncoprotein in human pancreatic cancer.
Author: Yamanaka, Y
PMID: 1347773
Journal: Zhonghua Zhong Liu Za Zhi. 1993 Jul;15(4):275-8.
Title: [Gene expression of TGF alpha, TGF beta 1 and C-erbB2 oncogene in human pancreatic carcinoma cell lines].
Author: Chen, J
PMID: 7909745
Journal: Jpn J Cancer Res. 1993 Feb;84(2):147-52.
Title: Construction of immunoradiometric assay for circulating c-erbB-2 protooncogene product in advanced breast cancer patients.
Author: Hosono, M|Saga, T|Sakahara, H|Kobayashi, H|Shirato, M|Endo, K|Yamamoto, T|Akiyama, T|Toyoshima, K|Konishi, J
PMID: 8096502
Journal: Hum Pathol. 1993 Oct;24(10):1127-34.
Title: Overexpression of HER2/neu oncogene in human pancreatic carcinoma.
Author: Yamanaka, Y|Friess, H|Kobrin, M S|Buchler, M|Kunz, J|Beger, H G|Korc, M
PMID: 8104858
Journal: Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):8972-6.
Title: Inverse regulation of human ERBB2 and epidermal growth factor receptors by tumor necrosis factor alpha.
Author: Kalthoff, H|Roeder, C|Gieseking, J|Humburg, I|Schmiegel, W
PMID: 8105469
Journal: Gene Ther. 1994 May;1(3):170-5.
Title: Gene therapy for cancer using tumour-specific prodrug activation.
Author: Harris, J D|Gutierrez, A A|Hurst, H C|Sikora, K|Lemoine, N R
PMID: 7584078
Journal: Virchows Arch. 1994;425(4):357-67.
Title: Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients.
Author: Sessa, F|Solcia, E|Capella, C|Bonato, M|Scarpa, A|Zamboni, G|Pellegata, N S|Ranzani, G N|Rickaert, F|Kloppel, G
PMID: 7820300
Journal: Hum Pathol. 1994 May;25(5):549-50.
Title: HER2/neu immunostaining in pancreatic carcinoma.
Author: Battifora, H
PMID: 7911120
Journal: Zentralbl Pathol. 1994 Aug;140(3):265-70.
Title: Expression of EGF, TGF-alpha, EGFR and c-erbB2 genes and their gene products in human pancreatic carcinoma cell lines.
Author: Chen, J|Liu, T H
PMID: 7947634
Journal: Int J Pancreatol. 1995 Aug;18(1):15-23.
Title: Frequent expression of genes for receptor tyrosine kinases and their ligands in human pancreatic cancer cells.
Author: Oikawa, T|Hitomi, J|Kono, A|Kaneko, E|Yamaguchi, K
PMID: 7594766
Journal: Oncology. 1995 Sep-Oct;52(5):392-6.
Title: Elevated serum c-erbB-2 protein levels in patients with pancreatic cancer: correlation to metastasis and shorter survival.
Author: Okada, N|Ohshio, G|Yamaki, K|Imamura, T|Imamura, M
PMID: 7637957
Journal: Anticancer Res. 1995 Jul-Aug;15(4):1135-9.
Title: In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin.
Author: Schultz, R M|Merriman, R L|Andis, S L|Bonjouklian, R|Grindey, G B|Rutherford, P G|Gallegos, A|Massey, K|Powis, G
PMID: 7653991
Journal: Eur J Surg Oncol. 1995 Jun;21(3):251-3.
Title: Oncogenes in cancer of the pancreas.
Author: Sakorafas, G H|Lazaris, A|Tsiotou, A G|Koullias, G|Glinatsis, M T|Golematis, B C
PMID: 7781791
Journal: Hum Pathol. 1996 Feb;27(2):119-24.
Title: Immunohistochemical evaluation of HER-2/neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms.
Author: Day, J D|Digiuseppe, J A|Yeo, C|Lai-Goldman, M|Anderson, S M|Goodman, S N|Kern, S E|Hruban, R H
PMID: 8617452
Journal: J Pathol. 1996 Feb;178(2):140-5.
Title: Overexpression of different members of the type 1 growth factor receptor family and their association with cell proliferation in periampullary carcinoma.
Author: Vaidya, P|Kawarada, Y|Higashiguchi, T|Yoshida, T|Sakakura, T|Yatani, R
PMID: 8683379
Journal: J Mol Med (Berl). 1996 Jan;74(1):35-42.
Title: Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors.
Author: Friess, H|Berberat, P|Schilling, M|Kunz, J|Korc, M|Buchler, M W
PMID: 8834768
Journal: Pancreas. 1997 Apr;14(3):229-36.
Title: HER-2/neu expression in pancreatic adenocarcinoma: relation to tumor differentiation and survival.
Author: Dugan, M C|Dergham, S T|Kucway, R|Singh, K|Biernat, L|Du, W|Vaitkevicius, V K|Crissman, J D|Sarkar, F H
PMID: 9094152
Journal: Mod Pathol. 1997 Apr;10(4):372-9.
Title: Hepatobiliary and pancreatic mucinous cystadenocarcinomas with mesenchymal stroma: analysis of estrogen receptors/progesterone receptors and expression of tumor-associated antigens.
Author: Weihing, R R|Shintaku, I P|Geller, S A|Petrovic, L M
PMID: 9110301
Journal: Eur J Immunol. 1997 May;27(5):1115-23.
Title: The HER2/neu-derived peptide p654-662 is a tumor-associated antigen in human pancreatic cancer recognized by cytotoxic T lymphocytes.
Author: Peiper, M|Goedegebuure, P S|Linehan, D C|Ganguly, E|Douville, C C|Eberlein, T J
PMID: 9174600
Journal: Surgery. 1997 Aug;122(2):235-41; discussion 241-2.
Title: Generation of peptide-specific cytotoxic T lymphocytes using allogeneic dendritic cells capable of lysing human pancreatic cancer cells.
Author: Peiper, M|Goedegebuure, P S|Eberlein, T J
PMID: 9288128
Journal: Int J Pancreatol. 1997 Jun;21(3):225-34.
Title: Relationship of family cancer history to the expression of p53, p21WAF-1, HER-2/neu, and K-ras mutation in pancreatic adenocarcinoma.
Author: Dergham, S T|Dugan, M C|Arlauskas, P|Du, W|Vaitkevicius, V K|Crissman, J D|Sarkar, F H
PMID: 9322121
Journal: Surg Oncol. 1997;6(1):1-18.
Title: The molecular genetics of pancreatic cancer.
Author: Howe, J R|Conlon, K C
PMID: 9364657
Journal: Ciba Found Symp. 1997;209:124-37; discussion 137-41.
Title: Differential oligonucleotide activity in cell culture versus mouse models.
Author: Wickstrom, E|Tyson, F L
PMID: 9383573
Journal: Cancer Res. 1998 Feb 15;58(4):732-6.
Title: Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes.
Author: Brossart, P|Stuhler, G|Flad, T|Stevanovic, S|Rammensee, H G|Kanz, L|Brugger, W
PMID: 9485028
Journal: Clin Cancer Res. 1998 Apr;4(4):887-94.
Title: An orthotopic model of human pancreatic cancer in severe combined immunodeficient mice: potential application for preclinical studies.
Author: Mohammad, R M|Al-Katib, A|Pettit, G R|Vaitkevicius, V K|Joshi, U|Adsay, V|Majumdar, A P|Sarkar, F H
PMID: 9563882
Journal: Am J Pathol. 1998 Jul;153(1):263-9.
Title: Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma.
Author: Liu, N|Furukawa, T|Kobari, M|Tsao, M S
PMID: 9665487
Journal: Front Biosci. 1998 Nov 1;3:E226-9.
Title: Novel approaches in development for the treatment of pancreatic cancer.
Author: Butera, J|Malachovsky, M|Rathore, R|Safran, H
PMID: 9792896
Journal: Pol J Pathol. 1998;49(2):83-92.
Title: HER-2/Neu expression as a progression marker in pancreatic intraepithelial neoplasia.
Author: Tomaszewska, R|Okon, K|Nowak, K|Stachura, J
PMID: 9798411
Journal: Crit Rev Eukaryot Gene Expr. 1998;8(3-4):377-93.
Title: The molecular and cellular biology of pancreatic cancer.
Author: Perugini, R A|McDade, T P|Vittimberga, F J Jr|Callery, M P
PMID: 9807701
Journal: Pancreas. 1998 Nov;17(4):325-33.
Title: Current concepts in pancreatic cancer: symposium summary.
Author: Dugan, M C|Sarkar, F H
PMID: 9821173
Journal: J Clin Pathol. 1998 Nov;51(11):865-7.
Title: Pancreatic cancer and fibrinogen storage disease.
Author: Radhi, J M|Lukie, B E
PMID: 10193333
Journal: Hum Pathol. 1999 Feb;30(2):123-9.
Title: Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic, and carcinomatous lesions of the pancreas: evidence for multistep carcinogenesis.
Author: Apple, S K|Hecht, J R|Lewin, D N|Jahromi, S A|Grody, W W|Nieberg, R K
PMID: 10029438
Journal: Ann Oncol. 1999;10 Suppl 4:145-9.
Title: Role of tumour markers, cytogenetics.
Author: Lamerz, R
PMID: 10436809
Journal: Anticancer Res. 1999 Jul-Aug;19(4A):2471-5.
Title: Pancreatic cancer associated ascites-derived CTL recognize a nine-amino-acid peptide GP2 derived from HER2/neu.
Author: Peiper, M|Goedegebuure, P S|Izbicki, J R|Eberlein, T J
PMID: 10470176
Journal: Ann Surg. 1999 Dec;230(6):767-74; discussion 774-5.
Title: Growth factor receptors are differentially expressed in cancers of the papilla of vater and pancreas.
Author: Friess, H|Wang, L|Zhu, Z|Gerber, R|Schroder, M|Fukuda, A|Zimmermann, A|Korc, M|Buchler, M W
PMID: 10615931
Journal: Folia Med Cracov. 1999;40(1-2):101-41.
Title: [Morphologic, morphometric and immunohistochemical studies on pancreatic intraductal hyperplasia and infiltrating carcinoma].
Author: Tomaszewska, R
PMID: 10909469
Journal: Invest New Drugs. 2000 Feb;18(1):43-56.
Title: Current approaches and future strategies for pancreatic carcinoma.
Author: Wolff, R A|Chiao, P|Lenzi, R|Pisters, P W|Lee, J E|Janjan, N A|Crane, C H|Evans, D B|Abbruzzese, J L
PMID: 10830140
Journal: Hematology Am Soc Hematol Educ Program. 2000:394-408.
Title: Emerging Therapies: Spectrum of Applications of Monoclonal Antibody Therapy.
Author: Waldmann, Thomas A.|Levy, Ronald|Coller, Barry S.
PMID: 11701553
Journal: J Gastrointest Surg. 2001 Mar-Apr;5(2):139-46.
Title: Therapy for pancreatic cancer with a recombinant humanized anti-HER2 antibody (herceptin).
Author: Buchler, P|Reber, H A|Buchler, M C|Roth, M A|Buchler, M W|Friess, H|Isacoff, W H|Hines, O J
PMID: 11331475
Journal: Arch Pathol Lab Med. 2001 Jun;125(6):765-9.
Title: An immunostaining panel for diagnosis of malignancy in mucinous tumors of the pancreas.
Author: Zhao, J|Liang, S X|Savas, L|Banner, B F
PMID: 11371228
Journal: Cancer Res. 2001 Jun 15;61(12):4885-91.
Title: Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors.
Author: Kusama, T|Mukai, M|Iwasaki, T|Tatsuta, M|Matsumoto, Y|Akedo, H|Nakamura, H
PMID: 11406567
Journal: Hepatogastroenterology. 2001 May-Jun;48(39):879-83.
Title: Immunohistochemical study of genetic alterations in intraductal and invasive ductal tumors of the pancreas.
Author: Islam, H K|Fujioka, Y|Tomidokoro, T|Sugiura, H|Takahashi, T|Kondo, S|Katoh, H
PMID: 11462947
Journal: Cancer J. 2001 Jul-Aug;7(4):349-58.
Title: Novel therapies for pancreatic cancer.
Author: Wolff, R A
PMID: 11561610
Journal: Neoplasma. 2001;48(3):188-91.
Title: Prognostic significance of c-erbB-2 gene expression in pancreatic cancer patients.
Author: Novotny, J|Petruzelka, L|Vedralova, J|Kleibl, Z|Matous, B|Juda, L
PMID: 11583287
Journal: Am J Clin Oncol. 2001 Oct;24(5):496-9.
Title: Overexpression of the HER-2/neu oncogene in pancreatic adenocarcinoma.
Author: Safran, H|Steinhoff, M|Mangray, S|Rathore, R|King, T C|Chai, L|Berzein, K|Moore, T|Iannitti, D|Reiss, P|Pasquariello, T|Akerman, P|Quirk, D|Mass, R|Goldstein, L|Tantravahi, U
PMID: 11586103
Journal: Tidsskr Nor Laegeforen. 2001 Oct 20;121(25):2941-5.
Title: [Tumor antigens presented to T helper lymphocytes--critical components of the cancer vaccine].
Author: Bartnes, K
PMID: 11715777
Journal: Cancer Res. 2001 Dec 15;61(24):8830-7.
Title: Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia.
Author: Biankin, A V|Kench, J G|Morey, A L|Lee, C S|Biankin, S A|Head, D R|Hugh, T B|Henshall, S M|Sutherland, R L
PMID: 11751405
Journal: Cancer Immunol Immunother. 2002 Jan;50(11):615-24. Epub 2001 Nov 23.
Title: HER-2/neu-derived peptide 884-899 is expressed by human breast, colorectal and pancreatic adenocarcinomas and is recognized by in-vitro-induced specific CD4(+) T cell clones.
Author: Perez, Sonia A|Sotiropoulou, Panagiota A|Sotiriadou, Nectaria N|Mamalaki, Avgi|Gritzapis, Angelos D|Echner, Hartmut|Voelter, Wolfgang|Pawelec, Graham|Papamichail, Michael|Baxevanis, Constantin N
PMID: 11807625
Journal: Gastroenterology. 2002 Jun;122(7):1898-912.
Title: Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells.
Author: Wagner, Martin|Weber, Christoph K|Bressau, Frank|Greten, Florian R|Stagge, Volker|Ebert, Matthias|Leach, Steven D|Adler, Guido|Schmid, Roland M
PMID: 12055597
Journal: Pancreas. 2002 Jul;25(1):e10-4.
Title: Palliative MEFLEP therapy in advanced pancreatic cancer: excellent response in a patient with Her-2/neu amplification.
Author: Chao, Yee|Liu, Jacqueline Ming|Li, Anna Fen Yau|Perng, Ching Lin|Tiu, Chue Mei|King, Kuan Liang|Chen, Li Tzong|Lin, Wei Chun|Lan, Chieh|Whang-Peng, Jacqueline
PMID: 12131783
Journal: Anticancer Res. 2002 May-Jun;22(3):1593-7.
Title: Role of immunohistochemical identification of Her-2/neu and detection of variability in overexpression in pancreatic carcinoma.
Author: Koka, Vijay|Potti, Anil|Koch, Michael|Fraiman, Genise|Mehdi, Syed|Levitt, Ralph
PMID: 12168842
Journal: Pancreas. 2002 Oct;25(3):e36-41.
Title: Fas and Fas ligand expression in pancreatic adenocarcinoma.
Author: Pernick, Nat L|Sarkar, Fazlul H|Tabaczka, Pam|Kotcher, Glenn|Frank, John|Adsay, N Volkan
PMID: 12370548
Journal: Genes Chromosomes Cancer. 2002 Dec;35(4):353-8.
Title: Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer.
Author: Mahlamaki, Eija H|Barlund, Maarit|Tanner, Minna|Gorunova, Ludmila|Hoglund, Mattias|Karhu, Ritva|Kallioniemi, Anne
PMID: 12378529
Journal: Anticancer Res. 2002 Nov-Dec;22(6A):3357-63.
Title: Comparison of various sources of antigen-presenting cells for the generation of GP2-tumor peptide specific cytotoxic T-lymphocytes.
Author: Peiper, Matthias|Goedegebuure, Peter S|Alldinger, Ingo|Knoefel, Wolfram Trudo|Izbicki, Jakob R|Eberlein, Timothy J
PMID: 12530087
Journal: Semin Oncol. 2002 Dec;29(6 Suppl 20):31-9.
Title: Future directions in the treatment of pancreatic cancer.
Author: Haller, Daniel G
PMID: 12577231
Journal: Int J Gastrointest Cancer. 2002;31(1-3):191-7.
Title: Minute invasive ductal carcinoma of the residual pancreas after distal pancreatectomy for intraductal papillary-mucinous tumor.
Author: Moriya, Toshiyuki|Kimura, Wataru|Sakurai, Fumiaki|Semba, Shuho|Ozawa, Koichiro|Hirai, Ichiro|Fuse, Akira
PMID: 12622431
Journal: Int J Gastrointest Cancer. 2002;32(2-3):91-106.
Title: Drug development in pancreatic cancer: finally, biology begets therapy.
Author: Cohen, Steven J|Meropol, Neal J
PMID: 12794245
Journal: Semin Oncol. 2003 Jun;30(3 Suppl 7):15-24.
Title: Preclinical studies with Erlotinib (Tarceva).
Author: Akita, Robert W|Sliwkowski, Mark X
PMID: 12840797
Journal: Anticancer Res. 2003 May-Jun;23(3B):2671-4.
Title: HER-2/neu and CD117 (C-kit) overexpression in hepatocellular and pancreatic carcinoma.
Author: Potti, Anil|Ganti, Apar Kishor|Tendulkar, Ketki|Chitajallu, Sidharth|Sholes, Kaley|Koch, Michael|Kargas, Steven
PMID: 12894556
Journal: Br J Cancer. 2003 Sep 1;89(5):899-906.
Title: Different mechanisms are implicated in ERBB2 gene overexpression in breast and in other cancers.
Author: Vernimmen, D|Gueders, M|Pisvin, S|Delvenne, P|Winkler, R
PMID: 12942124
Journal: Clin Cancer Res. 2003 Sep 15;9(11):4221-6.
Title: Differential vascular and transcriptional responses to anti-vascular endothelial growth factor antibody in orthotopic human pancreatic cancer xenografts.
Author: Bockhorn, Maximilian|Tsuzuki, Yoshikazu|Xu, Lei|Frilling, Andreja|Broelsch, Christoph E|Fukumura, Dai
PMID: 14519649
Journal: Nature. 2003 Oct 23;425(6960):851-6.
Title: Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.
Author: Thayer, Sarah P|di Magliano, Marina Pasca|Heiser, Patrick W|Nielsen, Corinne M|Roberts, Drucilla J|Lauwers, Gregory Y|Qi, Yan Ping|Gysin, Stephan|Fernandez-del Castillo, Carlos|Yajnik, Vijay|Antoniu, Bozena|McMahon, Martin|Warshaw, Andrew L|Hebrok, Matthi
PMID: 14520413
Journal: Oncogene. 2003 Oct 30;22(49):7781-95.
Title: Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
Author: DeArmond, Daniel|Brattain, Michael G|Jessup, John Milburn|Kreisberg, Jeffrey|Malik, Shazli|Zhao, Shujie|Freeman, James W
PMID: 14586404
Journal: Br J Cancer. 2003 Dec 1;89(11):2110-5.
Title: Incidence, mechanism and prognostic value of activated AKT in pancreas cancer.
Author: Schlieman, M G|Fahy, B N|Ramsamooj, R|Beckett, L|Bold, R J
PMID: 14647146
Journal: Scand J Gastroenterol Suppl. 2003;(239):94-9.
Title: Surveillance for familial pancreatic cancer.
Author: de Vos tot Nederveen Cappel, W H|Lagendijk, M A C|Lamers, C B H W|Morreau, H|Vasen, H F A
PMID: 14743890
Journal: Cancer Res. 2004 Jan 15;64(2):622-30.
Title: Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis.
Author: Singh, Ajay P|Moniaux, Nicolas|Chauhan, Subhash C|Meza, Jane L|Batra, Surinder K
PMID: 14744777
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Feb;26(1):79-82.
Title: [Recent advances in gene change of pancreatic cancer].
Author: Wang, Yu-yue|Cui, Quan-cai
PMID: 15052782
Journal: Hepatogastroenterology. 2004 Mar-Apr;51(56):334-7.
Title: Correlation of immunohistochemically detected HER-2/neu (c-erbB-2) with histological stage and perineural invasion in pancreatic cancer.
Author: Tamiolakis, D|Venizelos, I|Simopoulos, C|Kotini, A|Jivannakis, T|Papadopoulos, N
PMID: 15086152
Journal: Am J Surg Pathol. 2004 Jun;28(6):813-20.
Title: Ductuloinsular tumors of the pancreas: endocrine tumors with entrapped nonneoplastic ductules.
Author: van Eeden, Susanne|de Leng, Wendy W J|Offerhaus, G Johan A|Morsink, Folkert H|Weterman, Marian A J|de Krijger, Ronald R|Kloppel, Gunter|Klimstra, David S
PMID: 15166675
Journal: Oncogene. 2004 Jul 29;23(34):5729-38.
Title: A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
Author: Jonckheere, Nicolas|Perrais, Michael|Mariette, Christophe|Batra, Surinder K|Aubert, Jean-Pierre|Pigny, Pascal|Van Seuningen, Isabelle
PMID: 15184872
Journal: Int J Oncol. 2004 Sep;25(3):765-70.
Title: Identification and characterization of human DFNA5L, mouse Dfna5l, and rat Dfna5l genes in silico.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 15289881
Journal: Oncol Rep. 2004 Dec;12(6):1309-15.
Title: ErbB2 oncogene antibodies differentiate between the normal and diseased pancreas, and between chronic pancreatitis and pancreatic cancer.
Author: Standop, Jens|Schneider, Matthias|Ulrich, Alexis|Mathiak, Guenther|Brand, Randall E|Buechler, Markus W|Pour, Parviz M
PMID: 15547756
Journal: Cancer Invest. 2004;22(5):706-12.
Title: Herceptin and gemcitabine for metastatic pancreatic cancers that overexpress HER-2/neu.
Author: Safran, Howard|Iannitti, David|Ramanathan, Ramesh|Schwartz, Jonathan D|Steinhoff, Margaret|Nauman, Chris|Hesketh, Paul|Rathore, Ritesh|Wolff, Robert|Tantravahi, Umadevi|Hughes, T Marilyn|Maia, Chris|Pasquariello, Terry|Goldstein, Lisa|King, Thomas|Tsai, J
PMID: 15581051
Journal: J Gastrointest Surg. 2004 Dec;8(8):960-9; discussion 969-70.
Title: Mechanisms of resistance to Erbitux (anti-epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells.
Author: Arnoletti, J Pablo|Buchsbaum, Donald J|Huang, Zhi-qiang|Hawkins, Ashley E|Khazaeli, Muhamad B|Kraus, Matthias H|Vickers, Selwyn M
PMID: 15585383
Journal: Clin Cancer Res. 2004 Dec 1;10(23):7834-41.
Title: Targeting of HER2 antigen for the treatment of disseminated peritoneal disease.
Author: Milenic, Diane E|Garmestani, Kayhan|Brady, Erik D|Albert, Paul S|Ma, Dangshe|Abdulla, Alia|Brechbiel, Martin W
PMID: 15585615
Journal:
Title: [(11)C]N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
Author: Shan, Liang
PMID: 20641864
Journal: Cancer Detect Prev. 2005;29(1):8-14.
Title: Osteoclast-like giant cell tumor in mucinous cystadenocarcinoma of the pancreas: an immunohistochemical and molecular analysis.
Author: Sedivy, Roland|Kalipciyan, Maria|Mazal, Peter R|Wolf, Brigitte|Wrba, F|Karner-Hanusch, Judith|Muhlbacher, Ferdinand|Mader, Robert M
PMID: 15734212
Journal: Am J Clin Pathol. 2005 Jan;123(1):28-35.
Title: A subset of pancreatic adenocarcinomas demonstrates coamplification of topoisomerase IIalpha and HER2/neu: use of immunolabeling and multicolor FISH for potential patient screening andtreatment.
Author: Hansel, Donna E|Ashfaq, Raheela|Rahman, Ayman|Wanzer, Dana|Yeo, Charles J|Wilentz, Robb E|Maitra, Anirban
PMID: 15762277
Journal: Pancreatology. 2005;5(1):44-58. Epub 2005 Mar 15.
Title: ErbB2 growth factor receptor, a marker for neuroendocrine cells?
Author: Standop, Jens|Andrianifahanana, Mahefatiana|Moniaux, Nicolas|Schneider, Matthias|Ulrich, Alexis|Brand, Randall E|Wisecarver, James L|Bridge, Julia A|Buchler, Markus W|Adrian, Thomas E|Batra, Surinder K|Pour, Parviz M
PMID: 15775699
Journal: BMC Gastroenterol. 2005 Mar 31;5:12.
Title: Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Capan-1 pancreatic cancer cells.
Author: Shirk, Andrew J|Kuver, Rahul
PMID: 15801978
Journal: Histochem Cell Biol. 2005 Mar;123(3):229-38.
Title: Human archival tissues provide a valuable source for the analysis of spatial genome organization.
Author: Wiech, Thorsten|Timme, Sylvia|Riede, Florian|Stein, Stefan|Schuricke, Michael|Cremer, Christoph|Werner, Martin|Hausmann, Michael|Walch, Axel
PMID: 15827756
Journal: Curr Drug Targets. 2005 May;6(3):259-74.
Title: Small molecules with EGFR-TK inhibitor activity.
Author: Albanell, Joan|Gascon, Pere
PMID: 15857287
Journal: Gastroenterol Clin Biol. 2005 Apr;29(4):465-8.
Title: From pancreatic intraepithelial neoplasia to cancer: a dramatic progression with K-ras status analysis.
Author: Fernandez, Carla|Chetaille, Bruno|Tasei, Anne-Marie|Sastre, Bernard|Sahel, Jose|Payan-Defais, Marie-Jose
PMID: 15864214
Journal: Int J Gastrointest Cancer. 2005;35(2):111-9.
Title: Biological similarities and differences between pancreatic intraepithelial neoplasias and intraductal papillary mucinous neoplasms.
Author: Moriya, Toshiyuki|Kimura, Wataru|Semba, Shuho|Sakurai, Fumiaki|Hirai, Ichiro|Ma, Jinfeng|Fuse, Akira|Maeda, Kunihiko|Yamakawa, Mitsunori
PMID: 15879625
Journal: Breast Cancer Res. 2005;7(4):R394-401. Epub 2005 Mar 24.
Title: Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2.
Author: Cicenas, Jonas|Urban, Patrick|Vuaroqueaux, Vincent|Labuhn, Martin|Kung, Willy|Wight, Edward|Mayhew, Mark|Eppenberger, Urs|Eppenberger-Castori, Serenella
PMID: 15987444
Journal: Int J Oncol. 2005 Oct;27(4):1125-30.
Title: Combination therapy for advanced pancreatic cancer using Herceptin plus chemotherapy.
Author: Buchler, Peter|Reber, Howard A|Eibl, Guido|Roth, Mendel A|Buchler, Markus W|Friess, Helmut|Isacoff, William H|Hines, Oscar J
PMID: 16142331
Journal: Eur J Cancer. 2005 Oct;41(15):2213-36.
Title: Molecular prognostic markers in pancreatic cancer: a systematic review.
Author: Garcea, G|Neal, C P|Pattenden, C J|Steward, W P|Berry, D P
PMID: 16146690
Journal: Semin Radiat Oncol. 2005 Oct;15(4):254-64.
Title: Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects.
Author: Adsay, Nazmi Volkan|Basturk, Olca|Cheng, Jeanette D|Andea, Aleodor A
PMID: 16183479
Journal: Cancer Biother Radiopharm. 2005 Oct;20(5):557-68.
Title: Alpha-particle radioimmunotherapy of disseminated peritoneal disease using a (212)Pb-labeled radioimmunoconjugate targeting HER2.
Author: Milenic, Diane E|Garmestani, Kayhan|Brady, Erik D|Albert, Paul S|Ma, Dangshe|Abdulla, Alia|Brechbiel, Martin W
PMID: 16248771
Journal: Mol Cancer Ther. 2005 Dec;4(12):1943-51.
Title: Simultaneous targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways for pancreatic cancer therapy.
Author: Ali, Shadan|El-Rayes, Basil F|Sarkar, Fazlul H|Philip, Philip A
PMID: 16373709
Journal: Cancer Immunol Immunother. 2006 Jan;55(1):31-8.
Title: Release of iC3b from apoptotic tumor cells induces tolerance by binding to immature dendritic cells in vitro and in vivo.
Author: Schmidt, Jan|Klempp, Christoph|Buchler, Markus W|Marten, Angela
PMID: 15891882
Journal: J Med Chem. 2006 Feb 23;49(4):1475-85.
Title: Tyrosine kinase inhibitors. 19. 6-Alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB family of tyrosine kinase receptors.
Author: Klutchko, Sylvester R|Zhou, Hairong|Winters, R Thomas|Tran, Tuan P|Bridges, Alexander J|Althaus, Irene W|Amato, Danielle M|Elliott, William L|Ellis, Paul A|Meade, Mary Ann|Roberts, Billy J|Fry, David W|Gonzales, Andrea J|Harvey, Patricia J|Nelson, James M
PMID: 16480284
Journal: World J Gastroenterol. 2006 Jan 21;12(3):437-42.
Title: Differential c-erbB-1 and c-erbB-2 mRNA expression in cancer of the pancreas compared with cancer of the papilla of Vater.
Author: Prenzel, Klaus L|Warnecke-Eberz, Ute|Brabender, Jan|Baldus, Stephan E|Bollschweiler, Elfriede|Gutschow, Christian A|Drebber, Uta|Hoelscher, Arnulf H|Schneider, Paul M
PMID: 16489645
Journal: Med Sci Monit. 2006 Sep;12(9):RA186-93.
Title: Molecular pathogenesis of pancreatic adenocarcinoma: potential clinical implications.
Author: Talar-Wojnarowska, Renata|Malecka-Panas, Ewa
PMID: 16940943
Journal: Int J Cancer. 2007 Feb 1;120(3):514-23.
Title: Expression and differential signaling of heregulins in pancreatic cancer cells.
Author: Kolb, Armin|Kleeff, Jorg|Arnold, Nichole|Giese, Nathalia A|Giese, Thomas|Korc, Murray|Friess, Helmut
PMID: 17096356
Journal: Cancer Res. 2007 Jan 15;67(2):433-6.
Title: Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy.
Author: Singh, Ajay P|Chaturvedi, Pallavi|Batra, Surinder K
PMID: 17234748
Journal: Zhonghua Bing Li Xue Za Zhi. 2007 Feb;36(2):102-6.
Title: [Topoisomerase IIalpha and HER2/neu gene alterations and their correlation in pancreatic ductal adenocarcinomas].
Author: Liang, Zhi-Yong|Wang, Wen-Ze|Gao, Jie|Wu, Sha-Fei|Zeng, Xuan|Liu, Tong-Hua
PMID: 17493384
Journal: Clin Cancer Res. 2007 Jun 1;13(11):3356-62.
Title: In vivo therapeutic synergism of anti-epidermal growth factor receptor and anti-HER2 monoclonal antibodies against pancreatic carcinomas.
Author: Larbouret, Christel|Robert, Bruno|Navarro-Teulon, Isabelle|Thezenas, Simon|Ladjemi, Maha-Zohra|Morisseau, Sebastien|Campigna, Emmanuelle|Bibeau, Frederic|Mach, Jean-Pierre|Pelegrin, Andre|Azria, David
PMID: 17545543
Journal: Int J Cancer. 2007 Oct 1;121(7):1410-6.
Title: Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation.
Author: Algul, Hana|Wagner, Martin|Lesina, Marina|Schmid, Roland M
PMID: 17546589
Journal: Oncol Rep. 2007 Aug;18(2):433-9.
Title: Antitumor activity of a combination of trastuzumab (Herceptin) and oral fluoropyrimidine S-1 on human epidermal growth factor receptor 2-overexpressing pancreatic cancer.
Author: Saeki, Hiroyuki|Yanoma, Shunsuke|Takemiya, Shouji|Sugimasa, Yukio|Akaike, Makoto|Yukawa, Norio|Rino, Yasushi|Imada, Toshio
PMID: 17611667
Journal: Cancer Res. 2007 Aug 1;67(15):7256-65.
Title: Epidermal growth factor receptor tyrosine phosphorylation and signaling controlled by a nuclear receptor coactivator, amplified in breast cancer 1.
Author: Lahusen, Tyler|Fereshteh, Mark|Oh, Annabell|Wellstein, Anton|Riegel, Anna T
PMID: 17671194
Journal: Appl Immunohistochem Mol Morphol. 2007 Sep;15(3):299-304.
Title: Histologic and immunohistochemical changes in the stented common bile duct.
Author: Euscher, Elizabeth D|Marsh, William L Jr|Lucas, Joel G|Frankel, Wendy L
PMID: 17721275
Journal: Med Sci (Paris). 2007 Oct;23(10):800-3.
Title: [Combined anti-EGFR and anti-HER2 monoclonal antibodies: preclinical efficacy in the treatment of pancreatic cancer].
Author: Larbouret, Christel|Robert, Bruno|Teulon, Isabelle|Azria, David|Pelegrin, Andre
PMID: 17937885
Journal: Bull Cancer. 2007 Oct;94(10):860-2.
Title: [Combination of anti-EGFR and anti-HER2 antibodies: hope in pancreatic cancer treatment].
Author: Larbouret, Christel|Robert, Bruno|Teulon, Isabelle|Assenat, Eric|Azria, David|Pelegrin, Andre
PMID: 17964979
Journal: Fam Cancer. 2008;7(1):103-12. Epub 2007 Nov 9.
Title: Pancreatic cancer and the FAMMM syndrome.
Author: Lynch, Henry T|Fusaro, Ramon M|Lynch, Jane F|Brand, Randall
PMID: 17992582
Journal: Biochem Pharmacol. 2008 Feb 15;75(4):836-46.
Title: The immunocytokine scFv23/TNF targeting HER-2/neu induces synergistic cytotoxic effects with 5-fluorouracil in TNF-resistant pancreatic cancer cell lines.
Author: Lyu, Mi-Ae|Kurzrock, Razelle|Rosenblum, Michael G
PMID: 18082672
Journal: Clin Chem. 2008 Mar;54(3):582-9.
Title: Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Author: Fredriksson, Simon|Horecka, Joe|Brustugun, Odd Terje|Schlingemann, Joerg|Koong, Albert C|Tibshirani, Rob|Davis, Ronald W
PMID: 18171715
Journal: Gan To Kagaku Ryoho. 2008 Feb;35(2):351-60.
Title: [Future directions of anticancer drug development in Japan].
Author: Akaza, Hideyuki|Kawai, Koji|Tsuruo, Takashi|Tsukagoshi, Shigeru|Aiba, Keisuke|Shimada, Yasuhiro|Kakeji, Yoshihiro|Ishikawa, Hideki|Ikeda, Tadashi|Nakamura, Seigo|Tamura, Tomohide|Yamamoto, Nobuyuki|Isonishi, Seiji|Hinotsu, Shiro|Hirose, Masaru|Katsura, Ju
PMID: 18281781
Journal: Cancer Res. 2008 Apr 1;68(7):2065-70.
Title: MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells.
Author: Chaturvedi, Pallavi|Singh, Ajay P|Chakraborty, Subhankar|Chauhan, Subhash C|Bafna, Sangeeta|Meza, Jane L|Singh, Pankaj K|Hollingsworth, Michael A|Mehta, Parmender P|Batra, Surinder K
PMID: 18381409
Journal: Dig Dis Sci. 2008 Nov;53(11):3026-32.
Title: HER2 gene amplification and chromosome 17 copy number do not predict survival of patients with resected pancreatic adenocarcinoma.
Author: Sharif, Saima|Ramanathan, Ramesh K|Potter, Douglas|Cieply, Kathleen|Krasinskas, Alyssa M
PMID: 18463983
Journal: FASEB J. 2008 Aug;22(8):3035-45.
Title: Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases.
Author: Vincent, Audrey|Ducourouble, Marie-Paule|Van Seuningen, Isabelle
PMID: 18492726
Journal: Anticancer Res. 2008 Mar-Apr;28(2B):1399-404.
Title: Expression of EGF and EGFR strongly correlates with metastasis of pancreatic ductal carcinoma.
Author: Pryczynicz, Anna|Guzinska-Ustymowicz, Katarzyna|Kemona, Andrzej|Czyzewska, Jolanta
PMID: 18505086
Journal: J Immunother. 2008 Jul-Aug;31(6):537-44.
Title: Antitumor efficacy of trastuzumab in nude mice orthotopically xenografted with human pancreatic tumor cells expressing low levels of HER-2/neu.
Author: Pratesi, Graziella|Petrangolini, Giovanna|Tortoreto, Monica|Addis, Alessandro|Zunino, Franco|Calcaterra, Claudia|Merlo, Andrea|Tagliabue, Elda|Menard, Sylvie|Balsari, Andrea
PMID: 18528301
Journal: Eur J Gastroenterol Hepatol. 2008 Aug;20(8):713-5.
Title: Pancreatic cancer: a plea for good and comprehensive morphological studies.
Author: Algul, Hana|Schmid, Roland M
PMID: 18617774
Journal: Cancer Genomics Proteomics. 2008 May-Aug;5(3-4):161-8.
Title: Phosphoproteome and transcriptome analyses of ErbB ligand-stimulated MCF-7 cells.
Author: Nagashima, Takeshi|Oyama, Masaaki|Kozuka-Hata, Hiroko|Yumoto, Noriko|Sakaki, Yoshiyuki|Hatakeyama, Mariko
PMID: 18820370
Journal: Cancer Res. 2008 Nov 1;68(21):8938-44.
Title: Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells.
Author: Sung, Bokyung|Jhurani, Sonia|Ahn, Kwang Seok|Mastuo, Yoichi|Yi, Tingfang|Guha, Sushovan|Liu, Mingyao|Aggarwal, Bharat B
PMID: 18974138
Journal: Appl Immunohistochem Mol Morphol. 2009 Jan;17(1):31-9.
Title: Histologic, immunohistochemical, and molecular classification of 52 IPMNs of the pancreas.
Author: Chadwick, Barbara|Willmore-Payne, Carlynn|Tripp, Sheryl|Layfield, Lester J|Hirschowitz, Sharon|Holden, Joseph
PMID: 18813127
Journal: J Biol Chem. 2009 Jan 16;284(3):1385-93.
Title: The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells.
Author: Zhao, Yingshe|Min, Chengyin|Vora, Siddharth R|Trackman, Philip C|Sonenshein, Gail E|Kirsch, Kathrin H
PMID: 19029090
Journal: BMC Surg. 2009 Jan 8;9:1.
Title: A prospective, non-randomized phase II trial of Trastuzumab and Capecitabine in patients with HER2 expressing metastasized pancreatic cancer.
Author: Mihaljevic, Andre|Buchler, Peter|Harder, Jan|Hofheinz, Ralf|Gregor, Michael|Kanzler, Stephan|Schmiegel, Wolff|Heinemann, Volker|Endlicher, Esther|Kloppel, Gunter|Seufferlein, Thomas|Geissler, Michael
PMID: 19133157
Journal: Clin Cancer Res. 2009 Feb 1;15(3):924-32.
Title: A novel human Her-2/neu chimeric molecule expressed by Listeria monocytogenes can elicit potent HLA-A2 restricted CD8-positive T cell responses and impact the growth and spread of Her-2/neu-positive breast tumors.
Author: Seavey, Matthew M|Pan, Zhen-Kun|Maciag, Paulo C|Wallecha, Anu|Rivera, Sandra|Paterson, Yvonne|Shahabi, Vafa
PMID: 19188163
Journal: Cancer Res. 2009 Apr 1;69(7):2950-5.
Title: Associations between selected biomarkers and prognosis in a population-based pancreatic cancer tissue microarray.
Author: Takikita, Mikiko|Altekruse, Sean|Lynch, Charles F|Goodman, Mark T|Hernandez, Brenda Y|Green, Mark|Cozen, Wendy|Cockburn, Myles|Sibug Saber, Maria|Topor, Marie|Zeruto, Chris|Abedi-Ardekani, Behnoush|Reichman, Marsha E|Hewitt, Stephen M
PMID: 19276352
Journal: Cancer Sci. 2009 Jul;100(7):1243-7.
Title: HER2 overexpression correlates with survival after curative resection of pancreatic cancer.
Author: Komoto, Masahiro|Nakata, Bunzo|Amano, Ryosuke|Yamada, Nobuya|Yashiro, Masakazu|Ohira, Masaichi|Wakasa, Kenichi|Hirakawa, Kosei
PMID: 19432892
Journal: Mol Cancer Ther. 2009 May;8(5):1207-17.
Title: The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression.
Author: Liu, Xinyi|Abdelrahim, Maen|Abudayyeh, Ala|Lei, Ping|Safe, Stephen
PMID: 19435870
Journal: JOP. 2009 Jul 6;10(4):357-60.
Title: Pharmacogenetics in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009.
Author: Strimpakos, Alexios S|Syrigos, Kostas N|Saif, Muhammad Wasif
PMID: 19581734
Journal: Mayo Clin Proc. 2009 Sep;84(9):801-10.
Title: Fluorescence in situ hybridization to visualize genetic abnormalities in interphase cells of acinar cell carcinoma, ductal adenocarcinoma, and islet cell carcinoma of the pancreas.
Author: Dewald, Gordon W|Smyrk, Thomas C|Thorland, Erik C|McWilliams, Robert R|Van Dyke, Daniel L|Keefe, Jeannette G|Belongie, Kimberly J|Smoley, Stephanie A|Knutson, Darlene L|Fink, Stephanie R|Wiktor, Anne E|Petersen, Gloria M
PMID: 19720778
Journal: Br J Cancer. 2009 Oct 6;101(7):1155-61.
Title: Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin.
Author: Bafna, S|Kaur, S|Momi, N|Batra, S K
PMID: 19738614
Journal: Immunotherapy. 2009 Mar;1(2):223-9.
Title: Monoclonal antibodies in the treatment of pancreatic cancer.
Author: Huang, Zhi-Qiang|Buchsbaum, Donald J
PMID: 20046965
Journal: Folia Histochem Cytobiol. 2009;47(4):667-71.
Title: Expression of epidermal growth factors and apoptosis markers in pancreatic ductal adenocarcinoma.
Author: Pryczynicz, Anna|Guzinska-Ustymowicz, Katarzyna|Czyzewska, Jolanta|Kemona, Andrzej
PMID: 20430737
Journal: Ann Oncol. 2010 Jan;21(1):98-103.
Title: Combined cetuximab and trastuzumab are superior to gemcitabine in the treatment of human pancreatic carcinoma xenografts.
Author: Larbouret, C|Robert, B|Bascoul-Mollevi, C|Penault-Llorca, F|Ho-Pun-Cheung, A|Morisseau, S|Navarro-Teulon, I|Mach, J-P|Pelegrin, A|Azria, D
PMID: 19889608
Journal: Cancer Sci. 2010 Feb;101(2):468-73.
Title: In vitro and in vivo evidence that a combination of lapatinib plus S-1 is a promising treatment for pancreatic cancer.
Author: Komoto, Masahiro|Nakata, Bunzo|Nishii, Takafumi|Kawajiri, Hidemi|Shinto, Osamu|Amano, Ryosuke|Yamada, Nobuya|Yashiro, Masakazu|Hirakawa, Kosei
PMID: 19925494
Journal: Clin Cancer Res. 2010 Feb 1;16(3):912-23.
Title: Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status.
Author: Kimple, Randall J|Vaseva, Angelina V|Cox, Adrienne D|Baerman, Kathryn M|Calvo, Benjamin F|Tepper, Joel E|Shields, Janiel M|Sartor, Carolyn I
PMID: 20103665
Journal: Biochim Biophys Acta. 2010 Apr;1803(4):435-42.
Title: Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointestinal cancer cells.
Author: Lang, Sven A|Hackl, Christina|Moser, Christian|Fichtner-Feigl, Stefan|Koehl, Gudrun E|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 20116405
Journal: J Med Chem. 2010 Mar 11;53(5):2000-9.
Title: Discovery of 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide (CUDc-101) as a potent multi-acting HDAC, EGFR, and HER2 inhibitor for the treatment of cancer.
Author: Cai, Xiong|Zhai, Hai-Xiao|Wang, Jing|Forrester, Jeffrey|Qu, Hui|Yin, Ling|Lai, Cheng-Jung|Bao, Rudi|Qian, Changgeng
PMID: 20143778
Journal: Histopathology. 2010 Mar;56(4):440-8.
Title: Expression of L1CAM, COX-2, EGFR, c-KIT and Her2/neu in anaplastic pancreatic cancer: putative therapeutic targets?
Author: Bergmann, Frank|Moldenhauer, Gerhard|Herpel, Esther|Gaida, Matthias M|Strobel, Oliver|Werner, Jens|Esposito, Irene|Muerkoster, Susanne Sebens|Schirmacher, Peter|Kern, Michael A
PMID: 20459551
Journal: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2273-82.
Title: Cistaceae aqueous extracts containing ellagitannins show antioxidant and antimicrobial capacity, and cytotoxic activity against human cancer cells.
Author: Barrajon-Catalan, Enrique|Fernandez-Arroyo, Salvador|Saura, Domingo|Guillen, Emilio|Fernandez-Gutierrez, Alberto|Segura-Carretero, Antonio|Micol, Vicente
PMID: 20510328
Journal: Dis Markers. 2010;28(4):241-51.
Title: Alternative splice variants, a new class of protein cancer biomarker candidates: findings in pancreatic cancer and breast cancer with systems biology implications.
Author: Omenn, Gilbert S|Yocum, Anastasia K|Menon, Rajasree
PMID: 20534909
Journal: Biochem Pharmacol. 2010 Nov 15;80(10):1553-62.
Title: Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-kappaB activation in breast and pancreatic tumor cells.
Author: Chua, Angeline Wei Ling|Hay, Hui Sin|Rajendran, Peramaiyan|Shanmugam, Muthu K|Li, Feng|Bist, Pradeep|Koay, Evelyn S C|Lim, Lina H K|Kumar, Alan Prem|Sethi, Gautam
PMID: 20699088
Journal: J Cell Biochem. 2010 Dec 1;111(5):1160-8.
Title: Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis.
Author: Min, Chengyin|Zhao, Yingshe|Romagnoli, Mathilde|Trackman, Philip C|Sonenshein, Gail E|Kirsch, Kathrin H
PMID: 20717927
Journal: J Mol Med (Berl). 2010 Dec;88(12):1243-53.
Title: Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.
Author: Yadav, Vivek R|Sung, Bokyung|Prasad, Sahdeo|Kannappan, Ramaswamy|Cho, Sung-Gook|Liu, Mingyao|Chaturvedi, Madan M|Aggarwal, Bharat B
PMID: 20798912
Journal: Am J Pathol. 2010 Nov;177(5):2323-33.
Title: Loss of reelin expression in breast cancer is epigenetically controlled and associated with poor prognosis.
Author: Stein, Torsten|Cosimo, Emilio|Yu, Xinzi|Smith, Paul R|Simon, Ronald|Cottrell, Lorna|Pringle, Marie-Anne|Bell, Alexandra K|Lattanzio, Laura|Sauter, Guido|Lo Nigro, Cristiana|Crook, Timothy|Machesky, Laura M|Gusterson, Barry A
PMID: 20847288
Journal: Cancer Gene Ther. 2011 Jan;18(1):53-62.
Title: Development of a live and highly attenuated Listeria monocytogenes-based vaccine for the treatment of Her2/neu-overexpressing cancers in human.
Author: Shahabi, V|Seavey, M M|Maciag, P C|Rivera, S|Wallecha, A
PMID: 20725099
Journal: Exp Cell Res. 2011 Feb 15;317(4):392-404.
Title: Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines.
Author: Mill, Christopher P|Gettinger, Kathleen L|Riese, David J 2nd
PMID: 21110957
Journal: Bioorg Med Chem. 2011 Jan 1;19(1):67-76.
Title: Synthesis of a covalent gemcitabine-(carbamate)-[anti-HER2/neu] immunochemotherapeutic and its cytotoxic anti-neoplastic activity against chemotherapeutic-resistant SKBr-3 mammary carcinoma.
Author: Coyne, C P|Jones, Toni|Pharr, Todd
PMID: 21169024
Journal: J Immunol. 2011 Apr 1;186(7):4067-77.
Title: A novel tumor-associated pancreatic glycoprotein is internalized by human dendritic cells and induces their maturation.
Author: Franceschi, Cecile|Collignon, Aurelie|Isnardon, Daniel|Benkoel, Liliane|Verine, Alain|Silvy, Francoise|Bernard, Jean-Paul|Lombardo, Dominique|Beraud, Evelyne|Olive, Daniel|Mas, Eric
PMID: 21346236
Journal: Cancer Lett. 2011 Jul 28;306(2):180-9.
Title: RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation.
Author: Walsh, Naomi|Larkin, AnneMarie|Swan, Niall|Conlon, Kevin|Dowling, Paul|McDermott, Ray|Clynes, Martin
PMID: 21470770
Journal: Nanomedicine. 2011 Dec;7(6):859-70.
Title: Enhanced antiproliferative activity of Herceptin (HER2)-conjugated gemcitabine-loaded chitosan nanoparticle in pancreatic cancer therapy.
Author: Arya, Geetanjali|Vandana, Mallaredy|Acharya, Sarbari|Sahoo, Sanjeeb K
PMID: 21550422
Journal: Free Radic Biol Med. 2011 Sep 15;51(6):1164-74.
Title: Tocotrienols inhibit AKT and ERK activation and suppress pancreatic cancer cell proliferation by suppressing the ErbB2 pathway.
Author: Shin-Kang, Sonyo|Ramsauer, Victoria P|Lightner, Janet|Chakraborty, Kanishka|Stone, William|Campbell, Sharon|Reddy, Shrikanth A G|Krishnan, Koyamangalath
PMID: 21723941
Journal: J Vis Exp. 2011 Oct 25;(56):e3334.
Title: Heterogeneity mapping of protein expression in tumors using quantitative immunofluorescence.
Author: Faratian, Dana|Christiansen, Jason|Gustavson, Mark|Jones, Christine|Scott, Christopher|Um, InHwa|Harrison, David J
PMID: 22064683
Journal: Oncol Lett. 2011 Jan;2(1):161-166.
Title: Ductal adenocarcinoma of the pancreas: Expression of growth factor receptors, oncogenes and suppressor genes, and their relationship to pathological features, staging and survival.
Author: Lozano-Leon, Antonio|Perez-Quintela, Begona Vieites|Iglesias-Garcia, Julio|Larino-Noia, Jose|Varo, Evaristo|Forteza, Jeronimo|Dominguez-Munoz, J Enrique
PMID: 22870146
Journal: Am J Clin Oncol. 2011 Feb;34(1):50-2.
Title: Lapatinib and gemcitabine for metastatic pancreatic cancer. A phase II study.
Author: Safran, Howard|Miner, Thomas|Bahary, Nathan|Whiting, Sam|Lopez, Charles D|Sun, Weijing|Charpentier, Kevin|Shipley, Joshua|Anderson, Elliot|McNulty, Brendan|Schumacher, Andrew|Clark, Alessandra|Vakharia, Jamsheed|Kennedy, Teresa|Sio, Terence
PMID: 24757739
Journal: Mol Cancer Ther. 2012 Jan;11(1):24-33.
Title: MUC13 mucin augments pancreatic tumorigenesis.
Author: Chauhan, Subhash C|Ebeling, Mara C|Maher, Diane M|Koch, Michael D|Watanabe, Akira|Aburatani, Hiroyuki|Lio, Yuhlong|Jaggi, Meena
PMID: 22027689
Journal: J Cell Physiol. 2012 Oct;227(10):3381-8.
Title: Novel anti-ErbB3 monoclonal antibodies show therapeutic efficacy in xenografted and spontaneous mouse tumors.
Author: Aurisicchio, Luigi|Marra, Emanuele|Luberto, Laura|Carlomosti, Fabrizio|De Vitis, Claudia|Noto, Alessia|Gunes, Zeynep|Roscilli, Giuseppe|Mesiti, Giuseppe|Mancini, Rita|Alimandi, Maurizio|Ciliberto, Gennaro
PMID: 22213458
Journal: Br J Cancer. 2012 Mar 13;106(6):1033-8.
Title: Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer.
Author: Harder, J|Ihorst, G|Heinemann, V|Hofheinz, R|Moehler, M|Buechler, P|Kloeppel, G|Rocken, C|Bitzer, M|Boeck, S|Endlicher, E|Reinacher-Schick, A|Schmoor, C|Geissler, M
PMID: 22374460
Journal: PLoS One. 2012;7(2):e32232.
Title: The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways.
Author: Jonckheere, Nicolas|Skrypek, Nicolas|Merlin, Johann|Dessein, Anne Frederique|Dumont, Patrick|Leteurtre, Emmanuelle|Harris, Ann|Desseyn, Jean-Luc|Susini, Christiane|Frenois, Frederic|Van Seuningen, Isabelle
PMID: 22393391
Journal: Neoplasia. 2012 Feb;14(2):121-30.
Title: In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption.
Author: Larbouret, Christel|Gaborit, Nadege|Chardes, Thierry|Coelho, Mickael|Campigna, Emmanuelle|Bascoul-Mollevi, Caroline|Mach, Jean-Pierre|Azria, David|Robert, Bruno|Pelegrin, Andre
PMID: 22431920
Journal: Curr Drug Targets. 2012 Jun;13(6):802-10.
Title: Targeting EGFR in pancreatic cancer treatment.
Author: Troiani, T|Martinelli, E|Capasso, A|Morgillo, F|Orditura, Michele|De Vita, F|Ciardiello, F
PMID: 22458527
Journal: Cancer Res. 2012 May 15;72(10):2554-64.
Title: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.
Author: Kelber, Jonathan A|Reno, Theresa|Kaushal, Sharmeela|Metildi, Cristina|Wright, Tracy|Stoletov, Konstantin|Weems, Jessica M|Park, Frederick D|Mose, Evangeline|Wang, Yingchun|Hoffman, Robert M|Lowy, Andrew M|Bouvet, Michael|Klemke, Richard L
PMID: 22589274
Journal: BMC Med Genet. 2012 May 29;13:41.
Title: Relationships between the ABO blood group SNP rs505922 and breast cancer phenotypes: a genotype-phenotype correlation study.
Author: Rummel, Seth|Shriver, Craig D|Ellsworth, Rachel E
PMID: 22642827
Journal: PLoS One. 2012;7(6):e39684.
Title: Concomitant targeting of EGF receptor, TGF-beta and SRC points to a novel therapeutic approach in pancreatic cancer.
Author: Deharvengt, Sophie|Marmarelis, Melina|Korc, Murray
PMID: 22761868
Journal: Oncol Rep. 2012 Dec;28(6):2211-6.
Title: Dual ErbB1 and ErbB2 receptor tyrosine kinase inhibition exerts synergistic effect with conventional chemotherapy in pancreatic cancer.
Author: Singla, Smit|Pippin, James A|Drebin, Jeffrey A
PMID: 23007710
Journal: Coll Antropol. 2012 Sep;36(3):1063-7.
Title: Etiology and oncogenesis of pancreatic carcinoma.
Author: Dobrila-Dintinjana, Renata|Vanis, Nenad|Dintinjana, Marijan|Radic, Mladen
PMID: 23213974
Journal: Oncoimmunology. 2012 Nov 1;1(8):1387-1389.
Title: CAR's made it to the pancreas.
Author: Chmielewski, Markus|Maliar, Amit|Eshhar, Zelig|Abken, Hinrich
PMID: 23243602
Journal: J Cancer Ther. 2012 Oct;3(5A):689-711.
Title: Synthesis of Gemcitabine-(C4-amide)-[anti-HER2/neu] Utilizing a UV-Photoactivated Gemcitabine Intermediate: Cytotoxic Anti-Neoplastic Activity against Chemotherapeutic-Resistant Mammary Adenocarcinoma SKBr-3.
Author: Coyne, Cody P|Jones, Toni|Bear, Ryan
PMID: 26225216
Journal: Oncogene. 2013 Mar 14;32(11):1384-95.
Title: Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha7nAChR-mediated MUC4 upregulation.
Author: Momi, N|Ponnusamy, M P|Kaur, S|Rachagani, S|Kunigal, S S|Chellappan, S|Ouellette, M M|Batra, S K
PMID: 22614008
Journal: Invest New Drugs. 2013 Jun;31(3):558-66.
Title: EGFR and HER2 inhibition in pancreatic cancer.
Author: Walsh, Naomi|Kennedy, Susan|Larkin, AnneMarie|Corkery, Brendan|O'Driscoll, Lorraine|Clynes, Martin|Crown, John|O'Donovan, Norma
PMID: 23076814
Journal: Pancreas. 2013 Apr;42(3):411-21.
Title: Molecular markers for novel therapeutic strategies in pancreatic endocrine tumors.
Author: Gilbert, Judith A|Adhikari, Laura J|Lloyd, Ricardo V|Halfdanarson, Thorvardur R|Muders, Michael H|Ames, Matthew M
PMID: 23211371
Journal: J Natl Cancer Inst. 2013 Feb 20;105(4):266-73.
Title: HER3 overexpression and survival in solid tumors: a meta-analysis.
Author: Ocana, Alberto|Vera-Badillo, Francisco|Seruga, Bostjan|Templeton, Arnoud|Pandiella, Atanasio|Amir, Eitan
PMID: 23221996
Journal: Pancreas. 2013 Mar;42(2):216-22.
Title: Genetic alterations of K-ras, p53, c-erbB-2, and DPC4 in pancreatic ductal adenocarcinoma and their correlation with patient survival.
Author: Shin, Sang Hyun|Kim, Song Cheol|Hong, Seung-Mo|Kim, Young Hoon|Song, Ki-Byung|Park, Kwang-Min|Lee, Young-Joo
PMID: 23344532
Journal: World J Gastrointest Oncol. 2013 Jan 15;5(1):1-3.
Title: Complexity of molecular alterations impacts pancreatic cancer prognosis.
Author: Regel, Ivonne|Kong, Bo|Bruns, Philipp|Michalski, Christoph W|Kleeff, Jorg
PMID: 23355925
Journal: Cancer Res. 2013 Apr 1;73(7):2221-34.
Title: Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals.
Author: Miyabayashi, Koji|Ijichi, Hideaki|Mohri, Dai|Tada, Motohisa|Yamamoto, Keisuke|Asaoka, Yoshinari|Ikenoue, Tsuneo|Tateishi, Keisuke|Nakai, Yousuke|Isayama, Hiroyuki|Morishita, Yasuyuki|Omata, Masao|Moses, Harold L|Koike, Kazuhiko
PMID: 23378339
Journal: Cancer Discov. 2013 Mar;3(3):280-93.
Title: Outlier kinase expression by RNA sequencing as targets for precision therapy.
Author: Kothari, Vishal|Wei, Iris|Shankar, Sunita|Kalyana-Sundaram, Shanker|Wang, Lidong|Ma, Linda W|Vats, Pankaj|Grasso, Catherine S|Robinson, Dan R|Wu, Yi-Mi|Cao, Xuhong|Simeone, Diane M|Chinnaiyan, Arul M|Kumar-Sinha, Chandan
PMID: 23384775
Journal: Br J Cancer. 2013 Mar 19;108(5):1052-60.
Title: Biomarker results from the AVADO phase 3 trial of first-line bevacizumab plus docetaxel for HER2-negative metastatic breast cancer.
Author: Miles, D W|de Haas, S L|Dirix, L Y|Romieu, G|Chan, A|Pivot, X|Tomczak, P|Provencher, L|Cortes, J|Delmar, P R|Scherer, S J
PMID: 23422754
Journal: Neoplasia. 2013 Feb;15(2):143-55.
Title: Inhibition of the growth of patient-derived pancreatic cancer xenografts with the MEK inhibitor trametinib is augmented by combined treatment with the epidermal growth factor receptor/HER2 inhibitor lapatinib.
Author: Walters, Dustin M|Lindberg, James M|Adair, Sara J|Newhook, Timothy E|Cowan, Catharine R|Stokes, Jayme B|Borgman, Cheryl A|Stelow, Edward B|Lowrey, Bryce T|Chopivsky, Maria E|Gilmer, Tona M|Parsons, John T|Bauer, Todd W
PMID: 23441129
Journal: Cancer Lett. 2013 Oct 1;339(1):135-43.
Title: The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models.
Author: Shen, Ruizhe|Wang, Qi|Cheng, Shidan|Liu, Tingting|Jiang, He|Zhu, Jiaxing|Wu, Yunlin|Wang, Lifu
PMID: 23887057
Journal: Int J Pharm. 2013 Nov 1;456(1):202-11.
Title: Overcoming the stromal barrier for targeted delivery of HPMA copolymers to pancreatic tumors.
Author: Buckway, Brandon|Wang, Yongjian|Ray, Abhijit|Ghandehari, Hamidreza
PMID: 23933441
Journal: Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15389-94.
Title: Inhibition of pancreatic carcinoma by homo- and heterocombinations of antibodies against EGF-receptor and its kin HER2/ErbB-2.
Author: Maron, Ruth|Schechter, Bilha|Mancini, Maicol|Mahlknecht, Georg|Yarden, Yosef|Sela, Michael
PMID: 24003140
Journal: Genome Med. 2013 Aug 31;5(8):78.
Title: Clinical and molecular characterization of HER2 amplified-pancreatic cancer.
Author: Chou, Angela|Waddell, Nicola|Cowley, Mark J|Gill, Anthony J|Chang, David K|Patch, Ann-Marie|Nones, Katia|Wu, Jianmin|Pinese, Mark|Johns, Amber L|Miller, David K|Kassahn, Karin S|Nagrial, Adnan M|Wasan, Harpreet|Goldstein, David|Toon, Christopher W|Chin, V
PMID: 24004612
Journal: Breast Cancer Res Treat. 2013 Nov;142(2):311-22.
Title: Expression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in breast cancers.
Author: Tsang, Julia Y S|Kwok, Ying Kin|Chan, Kit Wing|Ni, Yun-Bi|Chow, Wan Ning Vanessa|Lau, Kwok Fai|Shao, Mu-Min|Chan, Siu Ki|Tan, Puay-Hoon|Tse, Gary M
PMID: 24186057
Journal: J Cancer Res Ther Oncol. 2013 Aug 22;1(1):10.
Title: Multiple Functional Motifs Are Required for the Tumor Suppressor Activity of a Constitutively-Active ErbB4 Mutant.
Author: Gallo, Richard M|Bryant, Ianthe N|Mill, Christopher P|Kaverman, Steven|Riese, David J 2nd
PMID: 24791013
Journal: Macromol Biosci. 2014 Jan;14(1):92-9.
Title: In vitro evaluation of HPMA-copolymers targeted to HER2 expressing pancreatic tumor cells for image guided drug delivery.
Author: Buckway, Brandon|Wang, Yongjian|Ray, Abhijit|Ghandehari, Hamidreza
PMID: 24038924
Journal: APMIS. 2014 Jun;122(6):476-81.
Title: Phosphorylation of STAT3 correlates with HER2 status, but not with survival in pancreatic ductal adenocarcinoma.
Author: Koperek, Oskar|Aumayr, Klaus|Schindl, Martin|Werba, Gregor|Soleiman, Afschin|Schoppmann, Sebastian|Sahora, Klaus|Birner, Peter
PMID: 24164699
Journal: Clin Cancer Res. 2014 Feb 1;20(3):688-700.
Title: MUC4-mediated regulation of acute phase protein lipocalin 2 through HER2/AKT/NF-kappaB signaling in pancreatic cancer.
Author: Kaur, Sukhwinder|Sharma, Neil|Krishn, Shiv Ram|Lakshmanan, Imay|Rachagani, Satyanarayana|Baine, Michael J|Smith, Lynette M|Lele, Subodh M|Sasson, Aaron R|Guha, Sushovan|Mallya, Kavita|Anderson, Judy M|Hollingsworth, Michael A|Batra, Surinder K
PMID: 24240113
Journal: Pharmacol Res. 2014 Jan;79:34-74.
Title: The ErbB/HER family of protein-tyrosine kinases and cancer.
Author: Roskoski, Robert Jr
PMID: 24269963
Journal: Cancer Res. 2014 Mar 1;74(5):1349-60.
Title: Novel bispecific antibodies increase gammadelta T-cell cytotoxicity against pancreatic cancer cells.
Author: Oberg, Hans-Heinrich|Peipp, Matthias|Kellner, Christian|Sebens, Susanne|Krause, Sarah|Petrick, Domantas|Adam-Klages, Sabine|Rocken, Christoph|Becker, Thomas|Vogel, Ilka|Weisner, Dietrich|Freitag-Wolf, Sandra|Gramatzki, Martin|Kabelitz, Dieter|Wesch, Danie
PMID: 24448235
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2014 Jun;387(6):505-21.
Title: A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer.
Author: Modjtahedi, Helmout|Cho, Byoung Chul|Michel, Martin C|Solca, Flavio
PMID: 24643470
Journal: Oncol Rep. 2014 May;31(5):2187-94.
Title: Upregulation of the splice variant MUC4/Y in the pancreatic cancer cell line MIA PaCa-2 potentiates proliferation and suppresses apoptosis: new insight into the presence of the transcript variant of MUC4.
Author: Xie, Kunling|Zhi, Xiaofei|Tang, Jie|Zhu, Yi|Zhang, Jingjing|Li, Zheng|Tao, Jinqiu|Xu, Zekuan
PMID: 24676527
Journal: Exp Cell Res. 2014 Aug 15;326(2):307-14.
Title: Induction of pancreatic cancer cell migration by an autocrine epidermal growth factor receptor activation.
Author: Stock, Anna-Maria|Hahn, Stephan A|Troost, Gabriele|Niggemann, Bernd|Zanker, Kurt S|Entschladen, Frank
PMID: 24810090
Journal: Mol Cancer. 2014 May 29;13:130.
Title: Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism.
Author: Zhang, Jing-Jing|Zhu, Yi|Xie, Kun-Ling|Peng, Yun-Peng|Tao, Jin-Qiu|Tang, Jie|Li, Zheng|Xu, Ze-Kuan|Dai, Cun-Cai|Qian, Zhu-Yin|Jiang, Kui-Rong|Wu, Jun-Li|Gao, Wen-Tao|Du, Qing|Miao, Yi
PMID: 24884523
Journal: Pharmacol Res. 2014 Sep;87:42-59.
Title: ErbB/HER protein-tyrosine kinases: Structures and small molecule inhibitors.
Author: Roskoski, Robert Jr
PMID: 24928736
Journal: PLoS One. 2014 Jun 20;9(6):e97239.
Title: Loss of stromal caveolin-1 expression: a novel tumor microenvironment biomarker that can predict poor clinical outcomes for pancreatic cancer.
Author: Shan, Tao|Lu, Hongwei|Ji, Hong|Li, Yiming|Guo, Jian|Chen, Xi|Wu, Tao
PMID: 24949874
Journal: Int J Nanomedicine. 2014 Jun 18;9:2933-42.
Title: Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy.
Author: Arora, Sumit|Swaminathan, Suresh K|Kirtane, Ameya|Srivastava, Sanjeev K|Bhardwaj, Arun|Singh, Seema|Panyam, Jayanth|Singh, Ajay P
PMID: 24971005
Journal: Neoplasia. 2014 Jul;16(7):562-71.
Title: Co-treatment with panitumumab and trastuzumab augments response to the MEK inhibitor trametinib in a patient-derived xenograft model of pancreatic cancer.
Author: Lindberg, James M|Newhook, Timothy E|Adair, Sara J|Walters, Dustin M|Kim, Alison J|Stelow, Edward B|Parsons, J Thomas|Bauer, Todd W
PMID: 25117978
Journal: Mol Ther. 2014 Dec;22(12):2056-68.
Title: Lentiviral vector-based insertional mutagenesis identifies genes involved in the resistance to targeted anticancer therapies.
Author: Ranzani, Marco|Annunziato, Stefano|Calabria, Andrea|Brasca, Stefano|Benedicenti, Fabrizio|Gallina, Pierangela|Naldini, Luigi|Montini, Eugenio
PMID: 25195596
Journal: Oncotarget. 2014 Aug 30;5(16):7138-48.
Title: HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models.
Author: Thomas, Gaelle|Chardes, Thierry|Gaborit, Nadege|Mollevi, Caroline|Leconet, Wilhem|Robert, Bruno|Radosevic-Robin, Nina|Penault-Llorca, Frederique|Gongora, Celine|Colombo, Pierre-Emmanuel|Lazrek, Yassamine|Bras-Goncalves, Rui|Savina, Ariel|Azria, David|Bazi
PMID: 25216528
Journal: Oncotarget. 2014 Sep 15;5(17):7599-609.
Title: MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer.
Author: Khan, Sheema|Ebeling, Mara C|Zaman, Mohd S|Sikander, Mohammed|Yallapu, Murali M|Chauhan, Neeraj|Yacoubian, Ashley M|Behrman, Stephen W|Zafar, Nadeem|Kumar, Deepak|Thompson, Paul A|Jaggi, Meena|Chauhan, Subhash C
PMID: 25277192
Journal: Oncoimmunology. 2014 Dec 21;3(11):e956005.
Title: IGF-1R peptide vaccines/mimics inhibit the growth of BxPC3 and JIMT-1 cancer cells and exhibit synergistic antitumor effects with HER-1 and HER-2 peptides.
Author: Foy, Kevin Chu|Miller, Megan J|Overholser, Jay|Donnelly, Siobhan M|Nahta, Rita|Kaumaya, Pravin Tp
PMID: 25941587
Journal: Oncoimmunology. 2014 Dec 21;3(11):e956012.
Title: HER-3 peptide vaccines/mimics: Combined therapy with IGF-1R, HER-2, and HER-1 peptides induces synergistic antitumor effects against breast and pancreatic cancer cells.
Author: Miller, Megan Jo|Foy, Kevin C|Overholser, Jay P|Nahta, Rita|Kaumaya, Pravin Tp
PMID: 25941588
Journal: Histol Histopathol. 2015 Jan;30(1):87-93.
Title: Overexpression of proCOL11A1 as a stromal marker of breast cancer.
Author: Fuentes-Martinez, Nelson|Garcia-Pravia, Carmen|Garcia-Ocana, Marcos|Menendez-Rodriguez, Primitiva|Del Amo, Jokin|Suarez-Fernandez, Laura|Galvan, Jose A|De los Toyos, Juan R|Barneo, Luis
PMID: 25005174
Journal: Gut. 2015 Nov;64(11):1790-9.
Title: SOX9 regulates ERBB signalling in pancreatic cancer development.
Author: Grimont, Adrien|Pinho, Andreia V|Cowley, Mark J|Augereau, Cecile|Mawson, Amanda|Giry-Laterriere, Marc|Van den Steen, Geraldine|Waddell, Nicola|Pajic, Marina|Sempoux, Christine|Wu, Jianmin|Grimmond, Sean M|Biankin, Andrew V|Lemaigre, Frederic P|Rooman, Ils
PMID: 25336113
Journal: Pathol Oncol Res. 2015 Jul;21(3):831-8.
Title: Prognostic value of increased HER2 expression in cancers of pancreas and biliary tree.
Author: Ata, Alper|Polat, Ayse|Serinsoz, Ebru|Sungur, Mehmet Ali|Arican, Ali
PMID: 25416598
Journal: Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Jan;119(1):e13-9.
Title: mTOR inhibitor-associated stomatitis (mIAS) in three patients with cancer treated with everolimus.
Author: Kalogirou, Eleni-Marina|Tosios, Konstantinos I|Piperi, Evangelia P|Sklavounou, Alexandra
PMID: 25442249
Journal: Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):839-44.
Title: Examination of HER3 targeting in cancer using monoclonal antibodies.
Author: Gaborit, Nadege|Abdul-Hai, Ali|Mancini, Maicol|Lindzen, Moshit|Lavi, Sara|Leitner, Orith|Mounier, Lucile|Chentouf, Myriam|Dunoyer, Sai|Ghosh, Manjusha|Larbouret, Christel|Chardes, Thierry|Bazin, Herve|Pelegrin, Andre|Sela, Michael|Yarden, Yosef
PMID: 25564668
Journal: Oncotarget. 2015 Mar 10;6(7):5164-81.
Title: Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer.
Author: Seshacharyulu, Parthasarathy|Ponnusamy, Moorthy P|Rachagani, Satyanarayana|Lakshmanan, Imayavaramban|Haridas, Dhanya|Yan, Ying|Ganti, Apar K|Batra, Surinder K
PMID: 25686822
Journal: Nature. 2015 Feb 26;518(7540):495-501.
Title: Whole genomes redefine the mutational landscape of pancreatic cancer.
Author: Waddell, Nicola|Pajic, Marina|Patch, Ann-Marie|Chang, David K|Kassahn, Karin S|Bailey, Peter|Johns, Amber L|Miller, David|Nones, Katia|Quek, Kelly|Quinn, Michael C J|Robertson, Alan J|Fadlullah, Muhammad Z H|Bruxner, Tim J C|Christ, Angelika N|Harliwong,
PMID: 25719666
Journal: Clin Cancer Res. 2015 Aug 1;21(15):3412-9.
Title: First-in-Human Pharmacokinetic and Pharmacodynamic Study of the Dual m-TORC 1/2 Inhibitor AZD2014.
Author: Basu, Bristi|Dean, Emma|Puglisi, Martina|Greystoke, Alastair|Ong, Michael|Burke, Wendy|Cavallin, Maria|Bigley, Graham|Womack, Christopher|Harrington, Elizabeth A|Green, Stephen|Oelmann, Elisabeth|de Bono, Johann S|Ranson, Malcolm|Banerji, Udai
PMID: 25805799
Journal: Oncotarget. 2015 May 10;6(13):10853-67.
Title: The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2.
Author: Skrypek, Nicolas|Vasseur, Romain|Vincent, Audrey|Duchene, Belinda|Van Seuningen, Isabelle|Jonckheere, Nicolas
PMID: 25890497
Journal: Biomaterials. 2015;53:731-43.
Title: Nanoparticle formulation of ormeloxifene for pancreatic cancer.
Author: Khan, Sheema|Chauhan, Neeraj|Yallapu, Murali M|Ebeling, Mara C|Balakrishna, Swathi|Ellis, Robert T|Thompson, Paul A|Balabathula, Pavan|Behrman, Stephen W|Zafar, Nadeem|Singh, Man M|Halaweish, Fathi T|Jaggi, Meena|Chauhan, Subhash C
PMID: 25890768
Journal: Clin Cancer Res. 2015 May 1;21(9):2029-37.
Title: Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial.
Author: Chantrill, Lorraine A|Nagrial, Adnan M|Watson, Clare|Johns, Amber L|Martyn-Smith, Mona|Simpson, Skye|Mead, Scott|Jones, Marc D|Samra, Jaswinder S|Gill, Anthony J|Watson, Nicole|Chin, Venessa T|Humphris, Jeremy L|Chou, Angela|Brown, Belinda|Morey, Adrienne
PMID: 25896973
Journal: Oncotarget. 2015 May 20;6(14):12796-808.
Title: Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the "THERAPY"phase 1-2 trial.
Author: Assenat, Eric|Azria, David|Mollevi, Caroline|Guimbaud, Rosine|Tubiana-Mathieu, Nicole|Smith, Denis|Delord, Jean-Pierre|Samalin, Emmanuelle|Portales, Fabienne|Larbouret, Christel|Robert, Bruno|Bibeau, Frederic|Bleuse, Jean-Pierre|Crapez, Evelyne|Ychou, Mar
PMID: 25918250
Journal: Oncotarget. 2015 Aug 21;6(24):20132-44.
Title: Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade.
Author: Umelo, Ijeoma Adaku|De Wever, Olivier|Kronenberger, Peter|Van Deun, Jan|Noor, Alfiah|Singh, Kshitiz|Teugels, Erik|Chen, Gang|Bracke, Marc|De Greve, Jacques
PMID: 25992771
Journal: Oncotarget. 2015 Aug 28;6(25):21085-99.
Title: Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells.
Author: Lakshmanan, Imayavaramban|Seshacharyulu, Parthasarathy|Haridas, Dhanya|Rachagani, Satyanarayana|Gupta, Suprit|Joshi, Suhasini|Guda, Chittibabu|Yan, Ying|Jain, Maneesh|Ganti, Apar K|Ponnusamy, Moorthy P|Batra, Surinder K
PMID: 26035354
Journal: Int J Mol Sci. 2015 Aug 17;16(8):19447-57.
Title: Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma.
Author: Gonzalez-Alonso, Paula|Chamizo, Cristina|Moreno, Victor|Madoz-Gurpide, Juan|Carvajal, Nerea|Daoud, Lina|Zazo, Sandra|Martin-Aparicio, Ester|Cristobal, Ion|Rincon, Raul|Garcia-Foncillas, Jesus|Rojo, Federico
PMID: 26287187
Journal: J Mol Diagn. 2015 Sep;17(5):487-95.
Title: Mutations in the Kinase Domain of the HER2/ERBB2 Gene Identified in a Wide Variety of Human Cancers.
Author: Wen, Wenhsiang|Chen, Wangjuh Sting|Xiao, Nick|Bender, Ryan|Ghazalpour, Anatole|Tan, Zheng|Swensen, Jeffrey|Millis, Sherri Z|Basu, Gargi|Gatalica, Zoran|Press, Michael F
PMID: 26320869
Journal: Pancreas. 2016 Mar;45(3):425-33.
Title: Nab-Paclitaxel Plus S-1 Shows Increased Antitumor Activity in Patient-Derived Pancreatic Cancer Xenograft Mouse Models.
Author: Li, Jian-Ang|Xu, Xue-Feng|Han, Xu|Fang, Yuan|Shi, Chen-Ye|Jin, Da-Yong|Lou, Wen-Hui
PMID: 26495780
Journal: Expert Opin Biol Ther. 2016;16(2):243-53.
Title: Pertuzumab in gastrointestinal cancer.
Author: Oh, Do-Youn|Bang, Yung-Jue
PMID: 26619359
Journal: Target Oncol. 2016 Jun;11(3):371-81.
Title: Afatinib, an Irreversible EGFR Family Inhibitor, Shows Activity Toward Pancreatic Cancer Cells, Alone and in Combination with Radiotherapy, Independent of KRAS Status.
Author: Huguet, Florence|Fernet, Marie|Giocanti, Nicole|Favaudon, Vincent|Larsen, Annette K
PMID: 26668065
Journal: PLoS One. 2016 Jan 25;11(1):e0147995.
Title: A Novel Biomarker Panel Examining Response to Gemcitabine with or without Erlotinib for Pancreatic Cancer Therapy in NCIC Clinical Trials Group PA.3.
Author: Shultz, David B|Pai, Jonathan|Chiu, Wayland|Ng, Kendall|Hellendag, Madeline G|Heestand, Gregory|Chang, Daniel T|Tu, Dongsheng|Moore, Malcolm J|Parulekar, Wendy R|Koong, Albert C
PMID: 26808546
Journal: Anticancer Res. 2016 Feb;36(2):517-21.
Title: Surgical and Oncological Factors Affecting the Successful Engraftment of Patient-derived Xenografts in Pancreatic Ductal Adenocarcinoma.
Author: Jun, Eunsung|Jung, Jaeyoon|Jeong, Seong-Yun|Choi, Eun Kyung|Kim, Moon Bo|Lee, Ji Sun|Hong, Seung-Mo|Seol, Hyang Sook|Hwang, Changmo|Hoffman, Robert M|Shim, In Kyong|Chang, Suhwan|Kim, Song Cheol
PMID: 26851005
Journal: World J Surg Oncol. 2016 Feb 20;14(1):38.
Title: Prognostic role of HER2 amplification based on fluorescence in situ hybridization (FISH) in pancreatic ductal adenocarcinoma (PDAC): a meta-analysis.
Author: Li, Xiaoping|Zhao, Hua|Gu, Jianchun|Zheng, Leizhen
PMID: 26897036
Journal: Oncol Lett. 2016 Mar;11(3):1645-1650.
Title: Circulating microRNA profile predicts disease progression in patients receiving second-line treatment of lapatinib and capecitabine for metastatic pancreatic cancer.
Author: Tian, Xuefei|Shivapurkar, Narayan|Wu, Zheng|Hwang, Jimmy J|Pishvaian, Michael J|Weiner, Louis M|Ley, Lisa|Zhou, Dan|Zhi, Xiuling|Wellstein, Anton|Marshall, John L|He, Aiwu Ruth
PMID: 26998056
Journal: PLoS One. 2016 Apr 12;11(4):e0153533.
Title: Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1, 2 and 3 in Periampullary Adenocarcinoma.
Author: Elebro, Jacob|Heby, Margareta|Warfvinge, Carl Fredrik|Nodin, Bjorn|Eberhard, Jakob|Jirstrom, Karin
PMID: 27070783
Journal: Br J Cancer. 2016 Jun 14;114(12):1376-86.
Title: Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation.
Author: Chugh, Seema|Meza, Jane|Sheinin, Yuri M|Ponnusamy, Moorthy P|Batra, Surinder K
PMID: 27187683
Journal: Cancer Lett. 2016 Aug 28;379(1):143-53.
Title: Combined targeting of TGF-beta, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model.
Author: Gore, Jesse|Imasuen-Williams, Imade E|Conteh, Abass M|Craven, Kelly E|Cheng, Monica|Korc, Murray
PMID: 27267807
Journal: Cancer Genet. 2016 Dec;209(12):567-581.
Title: Molecular targeted therapy for pancreatic adenocarcinoma: A review of completed and ongoing late phase clinical trials.
Author: Mosquera, Catalina|Maglic, Dino|Zervos, Emmanuel E
PMID: 27613577
Journal: Expert Opin Biol Ther. 2016 Dec;16(12):1549-1555.
Title: The prospect of patritumab for treating non-small cell lung cancer.
Author: Horinouchi, Hidehito
PMID: 27744717
Journal: BMC Cancer. 2016 Nov 21;16(1):910.
Title: The prognostic significance of human epidermal growth factor receptor family protein expression in operable pancreatic cancer : HER1-4 protein expression and prognosis in pancreatic cancer.
Author: Li, Qin|Zhang, Lei|Li, XiuHong|Yan, Han|Yang, Liuting|Li, Yingying|Li, Teng|Wang, Jing|Cao, Bangwei
PMID: 27871278
Journal: Nature. 2016 Dec 14. pii: nature20609.
Title: Mechanism of early dissemination and metastasis in Her2(+) mammary cancer.
Author: Harper, Kathryn L|Sosa, Maria Soledad|Entenberg, David|Hosseini, Hedayatollah|Cheung, Julie F|Nobre, Rita|Avivar-Valderas, Alvaro|Nagi, Chandandaneep|Girnius, Nomeda|Davis, Roger J|Farias, Eduardo F|Condeelis, John|Klein, Christoph A|Aguirre-Ghiso, Julio
PMID: 27974798
Journal: Oncotarget. 2017 Feb 14;8(7):10785-10808.
Title: Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens.
Author: Pathangey, Latha B|McCurry, Dustin B|Gendler, Sandra J|Dominguez, Ana L|Gorman, Jessica E|Pathangey, Girish|Mihalik, Laurie A|Dang, Yushe|Disis, Mary L|Cohen, Peter A
PMID: 27974697
Journal: Sci Rep. 2017 Jul 3;7(1):4537.
Title: Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway.
Author: Ren, Jian-Guo|Seth, Pankaj|Ye, Huihui|Guo, Kun|Hanai, Jun-Ichi|Husain, Zaheed|Sukhatme, Vikas P
PMID: 28674429
Journal: J Gastrointest Oncol. 2017 Jun;8(3):405-417.
Title: Predictive and prognostic biomarkers in personalized gastrointestinal cancer treatment.
Author: Verdaguer, Helena|Sauri, Tamara|Macarulla, Teresa
PMID: 28736628
Journal: Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):394-403.
Title: Clinical value of ctDNA in upper-GI cancers: A systematic review and meta-analysis.
Author: Creemers, A|Krausz, S|Strijker, M|van der Wel, M J|Soer, E C|Reinten, R J|Besselink, M G|Wilmink, J W|van de Vijver, M J|van Noesel, C J M|Verheij, J|Meijer, S L|Dijk, F|Bijlsma, M F|van Oijen, M G H|van Laarhoven, H W M
PMID: 28801248
Journal: Oncotarget. 2017 Apr 29;8(33):54592-54603.
Title: Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression.
Author: Link, Theresa|Kuithan, Friederike|Ehninger, Armin|Kuhlmann, Jan Dominik|Kramer, Michael|Werner, Andreas|Gatzweiler, Axel|Richter, Barbara|Ehninger, Gerhard|Baretton, Gustavo|Bachmann, Michael|Wimberger, Pauline|Friedrich, Katrin
PMID: 28903367
Journal: Monoclon Antib Immunodiagn Immunother. 2017 Dec;36(6):287-290.
Title: Establishment of H2Mab-119, an Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody, Against Pancreatic Cancer.
Author: Yamada, Shinji|Itai, Shunsuke|Nakamura, Takuro|Chang, Yao-Wen|Harada, Hiroyuki|Suzuki, Hiroyoshi|Kaneko, Mika K|Kato, Yukinari
PMID: 29172998
Journal: Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):486-489.
Title: Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy.
Author: Rao, Avani D|Liu, Yufei|von Eyben, Rie|Hsu, Charles C|Hu, Chen|Rosati, Lauren M|Parekh, Arti|Ng, Kendall|Hacker-Prietz, Amy|Zheng, Lei|Pawlik, Timothy M|Laheru, Daniel A|Jaffee, Elizabeth M|Weiss, Matthew J|Le, Dung T|Hruban, Ralph H|De Jesus-Acosta, Ana|
PMID: 29157747
Journal: Cancer Sci. 2018 Feb;109(2):373-383.
Title: PRDM14 directly interacts with heat shock proteins HSP90alpha and glucose-regulated protein 78.
Author: Moriya, Chiharu|Taniguchi, Hiroaki|Nagatoishi, Satoru|Igarashi, Hisayoshi|Tsumoto, Kouhei|Imai, Kohzoh
PMID: 29178343
Journal: J Oncol Pharm Pract. 2018 Apr;24(3):209-217.
Title: Association of hypertension and treatment outcomes in advanced stage non-small cell lung cancer patients treated with bevacizumab or non-bevacizumab containing regimens.
Author: Yan, Lily Z|Dressler, Emily V|Adams, Val R
PMID: 29284349
Journal: Oncogenesis. 2018 Feb 22;7(2):19.
Title: MUC13 contributes to rewiring of glucose metabolism in pancreatic cancer.
Author: Kumari, Sonam|Khan, Sheema|Gupta, Subash C|Kashyap, Vivek K|Yallapu, Murali M|Chauhan, Subhash C|Jaggi, Meena
PMID: 29467405
Journal: Sci Rep. 2018 Mar 15;8(1):4595.
Title: Single- and two-photon imaging of human micrometastases and disseminated tumour cells with conjugates of nanobodies and quantum dots.
Author: Ramos-Gomes, Fernanda|Bode, Julia|Sukhanova, Alyona|Bozrova, Svetlana V|Saccomano, Mara|Mitkovski, Miso|Krueger, Julia Eva|Wege, Anja K|Stuehmer, Walter|Samokhvalov, Pavel S|Baty, Daniel|Chames, Patrick|Nabiev, Igor|Alves, Frauke
PMID: 29545609
Journal: Sci Rep. 2018 Apr 18;8(1):6150.
Title: Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice.
Author: Shibata, Wataru|Kinoshita, Hiroto|Hikiba, Yohko|Sato, Takeshi|Ishii, Yasuaki|Sue, Soichiro|Sugimori, Makoto|Suzuki, Nobumi|Sakitani, Kosuke|Ijichi, Hideaki|Mori, Ryutaro|Endo, Itaru|Maeda, Shin
PMID: 29670173
Journal: Cancers (Basel). 2018 May 14;10(5). pii: cancers10050142.
Title: A New Strategy to Control and Eradicate "Undruggable" Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary Biology.
Author: Van Sciver, Robert E|Lee, Michael P|Lee, Caroline Dasom|Lafever, Alex C|Svyatova, Elizaveta|Kanda, Kevin|Colliver, Amber L|Siewertsz van Reesema, Lauren L|Tang-Tan, Angela M|Zheleva, Vasilena|Bwayi, Monicah N|Bian, Minglei|Schmidt, Rebecca L|Matrisian, Ly
PMID: 29757973
Journal: Gut. 2018 Aug 18. pii: gutjnl-2018-316595.
Title: Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma.
Author: Raj, Deepak|Yang, Ming-Hsin|Rodgers, David|Hampton, Eric N|Begum, Julfa|Mustafa, Arif|Lorizio, Daniela|Garces, Irene|Propper, David|Kench, James G|Young, Travis S|Aicher, Alexandra|Heeschen, Christopher
PMID: 30121627
Journal: Curr Treat Options Oncol. 2018 Aug 20;19(10):48.
Title: Harnessing the Immune System in Pancreatic Cancer.
Author: Das, Satya|Berlin, Jordan|Cardin, Dana
PMID: 30128712
Journal: Medicine (Baltimore). 2018 Sep;97(36):e11878.
Title: Incidental finding of a breast carcinoma on Ga-68-DOTA-1-Nal3-octreotide positron emission tomography/computed tomography performed for the evaluation of a pancreatic neuroendocrine tumor: A case report.
Author: Sampaio Vieira, Tiago|Borges Faria, Diogo|Souto Moura, Conceicao|Francisco, Elsa|Barroso, Sergio|Pereira de Oliveira, Jose
PMID: 30200073
Journal: Gene. 2018 Sep 15;679:328-334.
Title: Prognostic value of circulating cell-free DNA in patients with pancreatic cancer: A systemic review and meta-analysis.
Author: Chen, Linyan|Zhang, Yi|Cheng, Yuan|Zhang, Dan|Zhu, Sha|Ma, Xuelei
PMID: 30227250
Journal: Cancer Immunol Res. 2018 Oct 19. pii: 2326-6066.CIR-18-0070.
Title: Entinostat converts immune-resistant breast and pancreatic cancers into checkpoint-responsive tumors by reprogramming tumor-infiltrating MDSCs.
Author: Christmas, Brian J|Rafie, Christine I|Hopkins, Alexander C|Scott, Blake A|Ma, Hayley S|Cruz, Kayla A|Woolman, Skylar|Armstrong, Todd D|Connolly, Roisin M|Azad, Nilofer A|Jaffee, Elizabeth M|Roussos Torres, Evanthia T
PMID: 30341213
Journal: Oncologist. 2018 Oct 29. pii: theoncologist.2018-0152.
Title: Enrichment of HER2 Amplification in Brain Metastases from Primary Gastrointestinal Malignancies.
Author: Mitra, Devarati|Clark, Jeffrey W|Shih, Helen A|Oh, Kevin S|Brastianos, Priscilla K|Wo, Jennifer Y|Strickland, Matthew R|Curry, William T|Parikh, Aparna R|Corcoran, Ryan B|Ryan, David P|Iafrate, A John|Borger, Darrell R|Lennerz, Jochen K|Hong, Theodore S
PMID: 30373904
Journal: Toxins (Basel). 2018 Oct 31;10(11). pii: toxins10110447.
Title: Protein Synthesis Inhibition Activity of Mesothelin Targeting Immunotoxin LMB-100 Decreases Concentrations of Oncogenic Signaling Molecules and Secreted Growth Factors.
Author: El-Behaedi, Salma|Landsman, Rebekah|Rudloff, Michael|Kolyvas, Emily|Albalawy, Rakan|Zhang, Xianyu|Bera, Tapan|Collins, Keith|Kozlov, Serguei|Alewine, Christine
PMID: 30384408