Primary Site >> Colorectal Cancer

Gene >> ERBB2

1.
Journal: Gastroenterology. 1987 May;92(5 Pt 1):1174-80.
Title: Protooncogene abnormalities in colon cancers and adenomatous polyps.
Author: Meltzer, S J|Ahnen, D J|Battifora, H|Yokota, J|Cline, M J
PMID: 3557013
2.
Journal: Cancer Res. 1988 Mar 15;48(6):1517-20.
Title: Sporadic amplification of the HER2/neu protooncogene in adenocarcinomas of various tissues.
Author: Tal, M|Wetzler, M|Josefberg, Z|Deutch, A|Gutman, M|Assaf, D|Kris, R|Shiloh, Y|Givol, D|Schlessinger, J
PMID: 3345525
3.
Journal: Int J Cancer. 1990 Mar 15;45(3):457-61.
Title: Expression of the p185 encoded by HER2 oncogene in normal and transformed human tissues.
Author: Natali, P G|Nicotra, M R|Bigotti, A|Venturo, I|Slamon, D J|Fendly, B M|Ullrich, A
PMID: 1968437
4.
Journal: Jpn J Cancer Res. 1990 Sep;81(9):920-6.
Title: Correlation between the presence of microvilli and the growth or metastatic potential of tumor cells.
Author: Ren, J|Hamada, J|Okada, F|Takeichi, N|Morikawa, K|Hosokawa, M|Kobayashi, H
PMID: 1977729
5.
Journal: Cancer. 1990 Jan 1;65(1):88-92.
Title: c-erbB-2 oncoprotein expression in primary human tumors.
Author: McCann, A|Dervan, P A|Johnston, P A|Gullick, W J|Carney, D N
PMID: 2403483
6.
Journal: J Histochem Cytochem. 1991 Sep;39(9):1281-7.
Title: Immunohistochemical analysis of p53 and HER-2/neu proteins in human tumors.
Author: Chang, K|Ding, I|Kern, F G|Willingham, M C
PMID: 1680897
7.
Journal: Glycobiology. 1991 Nov;1(5):527-35.
Title: Biosynthesis in vitro of SA-Lex and SA-diLex by alpha 1-3 fucosyltransferases from colon carcinoma cells and embryonic brain tissues.
Author: Basu, M|Hawes, J W|Li, Z|Ghosh, S|Khan, F A|Zhang, B J|Basu, S
PMID: 1726578
8.
Journal: Nihon Geka Gakkai Zasshi. 1991 Oct;92(10):1469-79.
Title: [DNA content and c-erbB-2 oncoprotein expression in hepatic metastases from colorectal carcinoma--in relation to clinicopathologic findings and prognosis].
Author: Omori, K
PMID: 1961185
9.
Journal: Am J Med Sci. 1991 Apr;301(4):238-45.
Title: Enhanced expression of oncogene-encoded mRNA in a rat model of colon cancer.
Author: Alexander, R J|Buxbaum, J N|Raicht, R F
PMID: 2012108
10.
Journal: Surg Oncol. 1992 Feb;1(1):97-105.
Title: Correlation of epidermal growth factor receptor and c-erbB2 oncogene product to known prognostic indicators of colorectal cancer.
Author: Kluftinger, A M|Robinson, B W|Quenville, N F|Finley, R J|Davis, N L
PMID: 1285215
11.
Journal: Gan To Kagaku Ryoho. 1992 Jan;19(1):34-9.
Title: [Expression of c-erbB-2 protein and vessel invasion in colorectal cancer].
Author: Yamaguchi, S|Ohki, S|Jo, T|Imai, S|Matsuo, K|Hamahata, Y|Fukano, M|Tokito, S|Hasegawa, S|Masui, H
PMID: 1346087
12.
Journal: Int J Cancer. 1992 Mar 12;50(5):800-4.
Title: Human c-erbB-2 proto-oncogene product as a target for bispecific-antibody-directed adoptive tumor immunotherapy.
Author: Nishimura, T|Nakamura, Y|Tsukamoto, H|Takeuchi, Y|Tokuda, Y|Iwasawa, M|Yamamoto, T|Masuko, T|Hashimoto, Y|Habu, S
PMID: 1347516
13.
Journal: Oncology. 1992;49(2):162-5.
Title: Amplification of ERBB-2 (HER-2/NEU) oncogene in different neoplasms of patients from USSR.
Author: Knyazev, P G|Imyanitov, E N|Chernitca, O I|Nikiforova, I F|Hanson, K P
PMID: 1349430
14.
Journal: Anticancer Res. 1992 May-Jun;12(3):1013-8.
Title: Tumor-specific methylation patterns of erbB2 (HER2/neu) sequences in gastro-intestinal cancer.
Author: Holzmann, K|Welter, C|Klein, V|Pistorius, G|Seitz, G|Blin, N
PMID: 1352439
15.
Journal: Eur J Cancer. 1992;29A(1):170.
Title: c-erbB-2/neu in colorectal carcinoma: a potential prognostic value?
Author: Kapitanovic, S|Spaventi, R|Kusic, B|Pavelic, K
PMID: 1359899
16.
Journal: Acta Obstet Gynecol Scand Suppl. 1992;155:25-30.
Title: Oncogenesis in ovarian cancer.
Author: Borresen, A L
PMID: 1502889
17.
Journal: Cancer Lett. 1992 Jan 10;61(2):119-28.
Title: Detection of transforming oncogenes in rat colon tumors induced by direct perfusion with N-methyl-N-nitrosourea.
Author: Alexander, R J|Garte, S J|Raicht, R F|Buxbaum, J N
PMID: 1730134
18.
Journal: Oncogene. 1992 Jan;7(1):181-5.
Title: Overexpression of c-met proto-oncogene but not epidermal growth factor receptor or c-erbB-2 in primary human colorectal carcinomas.
Author: Liu, C|Park, M|Tsao, M S
PMID: 1741162
19.
Journal: J Natl Cancer Inst. 1993 Sep 1;85(17):1419-24.
Title: Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells.
Author: Pantel, K|Schlimok, G|Braun, S|Kutter, D|Lindemann, F|Schaller, G|Funke, I|Izbicki, J R|Riethmuller, G
PMID: 7688814
20.
Journal: Cancer Lett. 1993 Nov 30;75(1):41-4.
Title: HER-2/neu: a differentiation marker in adenocarcinoma of the esophagus.
Author: Sauter, E R|Keller, S M|Erner, S|Goldberg, M
PMID: 7904538
21.
Journal: Arch Surg. 1993 Jun;128(6):637-42.
Title: Expression of hormone receptors, cathepsin D, and HER-2/neu oncoprotein in normal colon and colonic disease.
Author: Galandiuk, S|Miseljic, S|Yang, A R|Early, M|McCoy, M D|Wittliff, J L
PMID: 8099272
22.
Journal: Zhonghua Yi Xue Za Zhi (Taipei). 1994 Aug;54(2):82-6.
Title: Serum c-erbB-2 oncoprotein in the diagnosis of gastric cancer in comparison with CA 19-9, CEA, TPA, CA 125 and AFP.
Author: Perng, C L|Lin, H J|Lee, S D
PMID: 7525029
23.
Journal: Gan To Kagaku Ryoho. 1994 Nov;21(15):2541-8.
Title: [Metastasis-related genes].
Author: Yokozaki, H|Tahara, E
PMID: 7526801
24.
Journal: Histopathology. 1994 Nov;25(5):455-61.
Title: Cytoplasmic c-erbB-2 protein expression correlates with survival in Dukes' B colorectal carcinoma.
Author: Kay, E W|Mulcahy, H|Walsh, C B|Leader, M|O'Donoghue, D
PMID: 7868086
25.
Journal: Acta Gastroenterol Belg. 1995 May-Aug;58(3-4):270-3.
Title: Contribution of molecular oncology in the detection of colorectal carcinomas.
Author: Ravelingien, N|Pector, J C|Velu, T
PMID: 7491839
26.
Journal: Histol Histopathol. 1995 Jul;10(3):661-8.
Title: Prognostic significance of p53 and c-erbB-2 immunohistochemical evaluation in colorectal adenocarcinoma.
Author: Lazaris, A C|Theodoropoulos, G E|Anastassopoulos, P|Nakopoulou, L|Panoussopoulos, D|Papadimitriou, K
PMID: 7579815
27.
Journal: APMIS. 1995 Apr;103(4):309-15.
Title: c-erbB-2 oncoprotein in relation to DNA ploidy and prognosis in colorectal adenocarcinoma.
Author: Sun, X F|Carstensen, J M|Stal, O|Zhang, H|Nordenskjold, B
PMID: 7612263
28.
Journal: Anticancer Res. 1995 Jul-Aug;15(4):1135-9.
Title: In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin.
Author: Schultz, R M|Merriman, R L|Andis, S L|Bonjouklian, R|Grindey, G B|Rutherford, P G|Gallegos, A|Massey, K|Powis, G
PMID: 7653991
29.
Journal: J Biol Chem. 1995 Jun 30;270(26):15591-7.
Title: Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha.
Author: Stover, D R|Becker, M|Liebetanz, J|Lydon, N B
PMID: 7797556
30.
Journal: Rinsho Byori. 1995 Jan;43(1):51-5.
Title: [Rearrangement of the c-erbB2 oncogene--analysis of the gastrocolic carcinoma].
Author: Kobayashi, H|Kawamura, M|Kusano, M|Watanabe, H|Fukuchi, K|Takagi, Y|Gomi, K
PMID: 7884965
31.
Journal: Anticancer Res. 1995 Nov-Dec;15(6B):2889-94.
Title: Expression of growth factors and their receptors in human early colorectal carcinomas: immunohistochemical study.
Author: Shirai, H|Ueno, E|Osaki, M|Tatebe, S|Ito, H|Kaibara, N
PMID: 8669884
32.
Journal: Semin Oncol. 1996 Feb;23(1):135-47.
Title: Polynucleotide-mediated immunization therapy of cancer.
Author: Conry, R M|LoBuglio, A F|Curiel, D T
PMID: 8607023
33.
Journal: Anticancer Res. 1996 May-Jun;16(3A):1197-202.
Title: nm23 expression in advanced and borderline ovarian carcinoma.
Author: Schneider, J|Romero, H|Ruiz, R|Centeno, M M|Rodriguez-Escudero, F J
PMID: 8702236
34.
Journal: J Surg Oncol. 1996 Sep;63(1):46-51.
Title: Modulation of colon tumor oncogene expression by cancer patient-derived lipids.
Author: Taylor, D D|Gercel-Taylor, C|Weese, J L
PMID: 8841466
35.
Journal: J Clin Oncol. 1996 Oct;14(10):2843-77.
Title: Clinical practice guidelines for the use of tumor markers in breast and colorectal cancer. Adopted on May 17, 1996 by the American Society of Clinical Oncology.
Author:
PMID: 8874347
36.
Journal: Ann Surg Oncol. 1996 Nov;3(6):574-9.
Title: Higher expression of oncoproteins c-myc, c-erb B-2/neu, PCNA, and p53 in metastasizing colorectal cancer than in nonmetastasizing tumors.
Author: Yang, J L|Ow, K T|Russell, P J|Ham, J M|Crowe, P J
PMID: 8915491
37.
Journal: Zhonghua Zhong Liu Za Zhi. 1996 Jul;18(4):247-9.
Title: [Relations between p53 and p185 expression and prognosis of patients with colon cancers].
Author: Hu, J|Wang, Z|Jiang, Y
PMID: 9387311
38.
Journal: Gastroenterology. 1997 Apr;112(4):1103-13.
Title: The expression of p185(HER-2/neu) correlates with the stage of disease and survival in colorectal cancer.
Author: Kapitanovic, S|Radosevic, S|Kapitanovic, M|Andelinovic, S|Ferencic, Z|Tavassoli, M|Primorac, D|Sonicki, Z|Spaventi, S|Pavelic, K|Spaventi, R
PMID: 9097992
39.
Journal: J R Coll Surg Edinb. 1997 Apr;42(2):98-101.
Title: Expression of growth factor receptors is not a prognostic indicator in young patients with colorectal cancer.
Author: Langlois, N|Walker, L G|Smith, I|Skinner, L|Eremin, O|Heys, S D
PMID: 9114679
40.
Journal: Gastroenterology. 1997 May;112(5):1457-65.
Title: Genetic alterations in gastric cancer: relation to histological subtypes, tumor stage, and Helicobacter pylori infection.
Author: Wu, M S|Shun, C T|Wang, H P|Sheu, J C|Lee, W J|Wang, T H|Lin, J T
PMID: 9136822
41.
Journal: Anticancer Res. 1997 Mar-Apr;17(2A):1023-6.
Title: Overexpression of c-erbB-2 mRNA and/or c-neu oncoprotein is a predictor for metastases from colorectal cancer.
Author: Yang, J L|Yu, Y|Markovic, B|Russell, P J|Crowe, P J
PMID: 9137444
42.
Journal: Tumour Biol. 1997;18(3):188-96.
Title: Serum levels of C-erbB-2 (HER-2/neu) in patients with malignant and non-malignant diseases.
Author: Molina, R|Jo, J|Filella, X|Bruix, J|Castells, A|Hague, M|Ballesta, A M
PMID: 9143415
43.
Journal: Int J Cancer. 1997 Jul 3;72(1):197-202.
Title: Expression of transgenic carcinoembryonic antigen (CEA) in tumor-prone mice: an animal model for CEA-directed tumor immunotherapy.
Author: Thompson, J A|Eades-Perner, A M|Ditter, M|Muller, W J|Zimmermann, W
PMID: 9212243
44.
Journal: Clin Exp Immunol. 1997 Jul;109(1):166-74.
Title: Isolation of human anti-c-erbB-2 Fabs from a lymph node-derived phage display library.
Author: Clark, M A|Hawkins, N J|Papaioannou, A|Fiddes, R J|Ward, R L
PMID: 9218840
45.
Journal: Cancer Epidemiol Biomarkers Prev. 1997 Sep;6(9):745-8.
Title: Molecular genetics of small bowel cancer.
Author: Arber, N|Neugut, A I|Weinstein, I B|Holt, P
PMID: 9298583
46.
Journal: Cytometry. 1997 Sep 1;29(1):1-27.
Title: Common patterns of genetic evolution in human solid tumors.
Author: Shackney, S E|Shankey, T V
PMID: 9298807
47.
Journal: J Natl Cancer Inst. 1997 Oct 15;89(20):1505-15.
Title: Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns.
Author: Wosikowski, K|Schuurhuis, D|Johnson, K|Paull, K D|Myers, T G|Weinstein, J N|Bates, S E
PMID: 9337347
48.
Journal: Oncogene. 1997 Nov 27;15(22):2705-16.
Title: ErbB kinases and NDF signaling in human prostate cancer cells.
Author: Grasso, A W|Wen, D|Miller, C M|Rhim, J S|Pretlow, T G|Kung, H J
PMID: 9400997
49.
Journal: Anticancer Res. 1997 Sep-Oct;17(5A):3463-8.
Title: In vivo overexpression of c-erbB-2 oncoprotein in xenografts of mice implanted with human colon cancer lines.
Author: Yang, J L|Hanley, J R|Yu, Y|Berney, C R|Russell, P J|Crowe, P J
PMID: 9413188
50.
Journal: Cancer Immunol Immunother. 1997 Nov-Dec;45(3-4):210-5.
Title: Clinical experience with CD64-directed immunotherapy. An overview.
Author: Curnow, R T
PMID: 9435876
51.
Journal: Oncogene. 1997 Dec 18;15(25):3083-90.
Title: Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential.
Author: Mao, W|Irby, R|Coppola, D|Fu, L|Wloch, M|Turner, J|Yu, H|Garcia, R|Jove, R|Yeatman, T J
PMID: 9444956
52.
Journal: Int J Immunopharmacol. 1997 Sep-Oct;19(9-10):481-5.
Title: Biomarkers for predicting response to regional chemo-immunotherapy in liver metastases from colorectal carcinoma.
Author: Zaloudik, J|Vagunda, V|Drahokoupilova, M|Janakova, L|Talac, R|Kalabis, J|Sheard, M
PMID: 9637342
53.
Journal: Cancer Res. 1998 Feb 15;58(4):732-6.
Title: Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes.
Author: Brossart, P|Stuhler, G|Flad, T|Stevanovic, S|Rammensee, H G|Kanz, L|Brugger, W
PMID: 9485028
54.
Journal: Histopathology. 1998 Jan;32(1):20-7.
Title: Value of a panel of antibodies to identify the primary origin of adenocarcinomas presenting as bladder carcinoma.
Author: Torenbeek, R|Lagendijk, J H|Van Diest, P J|Bril, H|van de Molengraft, F J|Meijer, C J
PMID: 9522212
55.
Journal: Oncol Res. 1998;10(1):47-54.
Title: Correlates of urokinase-type plasminogen activator in colorectal cancer: positive relationship with nm23 and c-erbB-2 protein expression.
Author: Berney, C R|Yang, J|Fisher, R J|Russell, P J|Crowe, P J
PMID: 9613457
56.
Journal: Hum Pathol. 1998 Aug;29(8):771-7.
Title: Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2.
Author: Maurer, C A|Friess, H|Kretschmann, B|Zimmermann, A|Stauffer, A|Baer, H U|Korc, M|Buchler, M W
PMID: 9712416
57.
Journal: Med Clin (Barc). 1998 Jul 11;111(5):168-71.
Title: [Expression of CD44 variant v6 in breast carcinoma and its relationship with other parameters of tumor biology].
Author: Aceituno, E|Turrion, F|San Roman, J M|Sarasa, J L|Ortiz, F|Garcia, R
PMID: 9732832
58.
Journal: Nihon Geka Gakkai Zasshi. 1998 Jul;99(7):402-8.
Title: [Dysfunction of E-cadherin-catenin system in invasion and metastasis of colorectal cancer].
Author: Maruyama, K|Ochiai, A|Nakamura, S|Baba, S|Hirohashi, S
PMID: 9742518
59.
Journal: Clin Biochem. 1998 Oct;31(7):523-8.
Title: Determination of p185 and adenylosuccinate lyase (ASL) activity in preneoplastic colon lesions and intestinal mucosa of human subjects.
Author: Terzuoli, L|Carlucci, F|Martino, A D|Frosi, B|Porcelli, B|Minacci, C|Vernillo, R|Baldi, L|Marinello, E|Pagani, R|Tabucchi, A
PMID: 9812171
60.
Journal: Clin Cancer Res. 1998 Nov;4(11):2669-76.
Title: Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens.
Author: Zhang, S|Zhang, H S|Cordon-Cardo, C|Ragupathi, G|Livingston, P O
PMID: 9829729
61.
Journal: Hunan Yi Ke Da Xue Xue Bao. 1998;23(2):129-32.
Title: [Expression and significance of p53, c-erbB2, CEA proteins in colorectal adenoma and carcinoma].
Author: Shu, M|Liu, S|Yu, P
PMID: 10681823
62.
Journal: Zhonghua Bing Li Xue Za Zhi. 1998 Feb;27(1):43-5.
Title: [Multivariate analysis of clinicopathological and immunohistochemical factors in colorectal carcinomas].
Author: Liu, H|Wu, Y|Yang, Y
PMID: 11244942
63.
Journal: Oncogene. 1999 Jan 14;18(2):305-14.
Title: Regulation of cyclooxygenase-2 pathway by HER2 receptor.
Author: Vadlamudi, R|Mandal, M|Adam, L|Steinbach, G|Mendelsohn, J|Kumar, R
PMID: 9927187
64.
Journal: Semin Nucl Med. 1999 Jan;29(1):41-8.
Title: Breast cancer imaging with radiolabeled antibodies.
Author: Goldenberg, D M|Nabi, H A
PMID: 9990682
65.
Journal: Cancer Res. 1999 Jun 15;59(12):2931-8.
Title: KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules.
Author: Soga, S|Neckers, L M|Schulte, T W|Shiotsu, Y|Akasaka, K|Narumi, H|Agatsuma, T|Ikuina, Y|Murakata, C|Tamaoki, T|Akinaga, S
PMID: 10383157
66.
Journal: Hum Immunol. 1999 Jun;60(6):510-5.
Title: Antibody immunity to the HER-2/neu oncogenic protein in patients with colorectal cancer.
Author: Ward, R L|Hawkins, N J|Coomber, D|Disis, M L
PMID: 10408800
67.
Journal: Ann Surg. 1999 Aug;230(2):179-84.
Title: Protein markers in colorectal cancer: predictors of liver metastasis.
Author: Berney, C R|Fisher, R J|Yang, J|Russell, P J|Crowe, P J
PMID: 10450731
68.
Journal: Anticancer Res. 1999 May-Jun;19(3A):2147-55.
Title: Immunohistochemical evaluation of cathepsin D expression in colorectal tumours: a correlation with extracellular matrix components, p53, pRb, bcl-2, c-erbB-2, EGFR and proliferation indices.
Author: Ioachim, E E|Goussia, A C|Machera, M|Tsianos, E V|Kappas, A M|Agnantis, N J
PMID: 10470163
69.
Journal: Int J Cancer. 1999 Nov 26;83(5):579-84.
Title: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.
Author: Chen, W S|Kung, H J|Yang, W K|Lin, W c
PMID: 10521789
70.
Journal: J Neurosci. 1999 Nov 15;19(22):9900-12.
Title: Altered midline axon pathways and ectopic neurons in the developing hypothalamus of netrin-1- and DCC-deficient mice.
Author: Deiner, M S|Sretavan, D W
PMID: 10559399
71.
Journal: J Clin Pathol. 1999 Dec;52(12):876-9.
Title: Prognostic evaluation of metallothionein expression in human colorectal neoplasms.
Author: Ioachim, E E|Goussia, A C|Agnantis, N J|Machera, M|Tsianos, E V|Kappas, A M
PMID: 10711249
72.
Journal: Breast Cancer. 1999 Oct 25;6(4):270-274.
Title: Current Status and Perspectives in Cancer Chemotherapy.
Author: Ogawa
PMID: 11091728
73.
Journal: Gut. 2000 Feb;46(2):200-4.
Title: Replication error phenotype, clinicopathological variables, and patient outcome in Dukes' B stage II (T3,N0,M0) colorectal cancer.
Author: Curran, B|Lenehan, K|Mulcahy, H|Tighe, O|Bennett, M A|Kay, E W|O'Donoghue, D P|Leader, M|Croke, D T
PMID: 10644313
74.
Journal: Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1230-5.
Title: Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster.
Author: Bai, C|Connolly, B|Metzker, M L|Hilliard, C A|Liu, X|Sandig, V|Soderman, A|Galloway, S M|Liu, Q|Austin, C P|Caskey, C T
PMID: 10655513
75.
Journal: J Biol Chem. 2000 Mar 3;275(9):6600-7.
Title: Characterization of a repressor element and a juxtaposed tissue-restricted activator element located on the distal neu gene promoter.
Author: Suen, T C|Goss, P E
PMID: 10692468
76.
Journal: Int J Cancer. 2000 Mar 15;85(6):796-800.
Title: Germline BRCA1 and HMLH1 mutations in a family with male and female breast carcinoma.
Author: Borg, A|Isola, J|Chen, J|Rubio, C|Johansson, U|Werelius, B|Lindblom, A
PMID: 10709098
77.
Journal: Eur J Cancer Prev. 2000 Aug;9(4):265-8.
Title: Different expression of some molecular markers in sporadic cancer of the left and right colon.
Author: Fric, P|Sovova, V|Sloncova, E|Lojda, Z|Jirasek, A|Cermak, J
PMID: 10958329
78.
Journal: Kaohsiung J Med Sci. 2000 May;16(5):233-40.
Title: The DCC protein expression in breast carcinoma.
Author: Hsu, Y H|Shaw, C K
PMID: 10969518
79.
Journal: Cancer Res. 2000 Sep 1;60(17):4850-4.
Title: Natural T-cell response against MHC class I epitopes of epithelial cell adhesion molecule, her-2/neu, and carcinoembryonic antigen in patients with colorectal cancer.
Author: Nagorsen, D|Keilholz, U|Rivoltini, L|Schmittel, A|Letsch, A|Asemissen, A M|Berger, G|Buhr, H J|Thiel, E|Scheibenbogen, C
PMID: 10987297
80.
Journal: Int J Cancer. 2000 Dec 15;88(6):956-61.
Title: T cell responses in colorectal cancer patients: evidence for class II HLA-restricted recognition of shared tumor-associated antigens.
Author: Bremers, A J|Andreola, S|Leo, E|Gallino, F|Rini, F|Lombardo, C|Belli, F|Kuppen, P J|Parmiani, G|Castelli, C
PMID: 11093821
81.
Journal: Int J Surg Investig. 2000;1(6):483-93.
Title: C-erbB-2 oncoprotein content in colorectal cancer and in surrounding mucosa: relationship with clinicopathologic parameters and prognostic significance.
Author: Vizoso, F|Villar, C|Rodriguez, J C|Raigoso, P|Garcia-Muniz, J L|Allende, M T|Garcia-Moran, M
PMID: 11729856
82.
Journal: Pathol Oncol Res. 2001;7(1):24-7.
Title: Expression of Bcl-2 and c-ErbB-2 in colorectal neoplasia.
Author: Dursun, A|Poyraz, A|Suer O|Sezer, C|Akyol, G
PMID: 11349216
83.
Journal: Histochem J. 2001 Jan;33(1):51-7.
Title: Expression of p185 and p53 in benign and malignant colorectal lesions.
Author: Porcelli, B|Frosi, B|Terzuoli, L|Arezzini, L|Marinello, E|Vernillo, R|De Martino, A|Vatti, R|Minacci, C
PMID: 11352401
84.
Journal: Gastroenterology. 2001 Jun;120(7):1713-9.
Title: Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth.
Author: Mann, M|Sheng, H|Shao, J|Williams, C S|Pisacane, P I|Sliwkowski, M X|DuBois, R N
PMID: 11375952
85.
Journal: Nihon Geka Gakkai Zasshi. 2001 May;102(5):370-5.
Title: [Genetic changes in liver metastasis of colorectal cancer and their clinical application].
Author: Yamaguchi, A
PMID: 11393998
86.
Journal: Z Gastroenterol. 2001 May;39(5):365-7.
Title: [Colorectal carcinoma in Cronkhite-Canada syndrome].
Author: Zugel, N P|Hehl, J A|Jechart, G|Tannapfel, A|Wienbeck, M|Witte, J
PMID: 11413916
87.
Journal: Cancer Invest. 2001;19(5):554-68.
Title: The HER-2/neu oncogene in tumors of the gastrointestinal tract.
Author: Ross, J S|McKenna, B J
PMID: 11458821
88.
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Title: Listeria monocytogenes produces a pro-invasive factor that signals via ErbB2/ErbB3 heterodimers.
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Journal: Gynecol Oncol. 2005 Jan;96(1):159-67.
Title: COX-2, c-KIT and HER-2/neu expression in uterine carcinosarcomas: prognostic factors or potential markers for targeted therapies?
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Title: Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.
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Title: New drugs in cancer therapy, National Tumor Institute, Naples, 17-18 June 2004.
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Title: T cell responses against tumor associated antigens and prognosis in colorectal cancer patients.
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Title: Quercetin decreases the expression of ErbB2 and ErbB3 proteins in HT-29 human colon cancer cells.
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Title: Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen.
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Title: Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.
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Title: (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells.
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Title: Antiangiogenesis and anticancer efficacy of TA138, a novel alphavbeta3 antagonist.
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Title: Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
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Title: Reorganization of ErbB family and cell survival signaling after Knock-down of ErbB2 in colon cancer cells.
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Title: HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.
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Title: [Study on the prognostic factors of colorectal cancer after radical resection and on suggested model for prediction].
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Title: Expression of p53, DCC, and HER-2/neu in mucinous carcinoma of the breast.
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Title: Synergy of epidermal growth factor receptor kinase inhibitor AG1478 and ErbB2 kinase inhibitor AG879 in human colon carcinoma cells is associated with induction of apoptosis.
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Title: EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.
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Title: [Monoclonal antibody against G3BP: preparation, characterization and its application in analysis of human tumors].
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Title: The usefulness of CDX-2 for differentiating primary and metastatic ovarian carcinoma: an immunohistochemical study using a tissue microarray.
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Title: Potential use of COX-2-aromatase inhibitor combinations in breast cancer.
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Title: Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid decreases ErbB3 expression in HT-29 human colon cancer cells.
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Title: Establishment and characterization of a human colonic mucinous carcinoma cell line with predominant goblet-cell differentiation from liver metastasis.
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Title: Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression.
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Title: Vascular endothelial growth factor, c-erbB-2 and c-erbB-3 expression in colorectal adenoma and adenocarcinoma.
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Title: Potential diagnostic utility of CDX-2 immunophenotyping in extramammary Paget's disease.
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Title: Assessment of staging, prognosis and mortality of colorectal cancer by tumor markers: receptor erbB-2 and cadherins.
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Title: Non-invasive detection of c-myc p64, c-myc p67 and c-erbb-2 in colorectal cancer.
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Title: Current status of small-molecule tyrosine kinase inhibitors targeting epidermal growth factor receptor in colorectal cancer.
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Journal: J Med Food. 2005 Winter;8(4):431-8.
Title: Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein.
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Title: EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
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Title: Immunogenic HER-2/neu peptides as tumor vaccines.
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Title: Somatic mutations of the ERBB4 kinase domain in human cancers.
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Title: Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines.
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Title: Tumor cell dissemination in colon cancer does not predict extrahepatic recurrence in patients undergoing surgery for hepatic metastases.
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Title: Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas.
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Journal: Cancer Res. 2006 Jan 1;66(1):404-11.
Title: Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis.
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Title: HER 2/neu protein expression in colorectal cancer.
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Title: Development of antibodies and chimeric molecules for cancer immunotherapy.
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Title: Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci.
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Journal: Cancer J. 2006 May-Jun;12(3):229-36.
Title: Clinicopathologic significance of EGFR and Her-2/neu in colorectal adenocarcinomas.
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Title: Compensatory increases in Her-2/neu activation in response to EGFR tyrosine kinase inhibition in colon cancer cell lines.
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Title: Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway.
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Journal: Clin Cancer Res. 2006 Dec 15;12(24):7422-30.
Title: Active antiviral T-lymphocyte response can be redirected against tumor cells by antitumor antibody x MHC/viral peptide conjugates.
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Title: Immunohistochemical expression of bcl-2 in UICC stage I and III colorectal carcinoma patients: correlation with c-erbB-2, p53, ki-67, CD44, laminin and collagen IV in evaluating prognostic significance.
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Title: HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer.
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Title: HER-2/neu overexpression is an independent prognostic factor in colorectal cancer.
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Title: Prospective study of positron emission tomography for evaluation of the activity of lapatinib, a dual inhibitor of the ErbB1 and ErbB2 tyrosine kinases, in patients with advanced tumors.
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Title: Preoperative serum levels of c-erbB-2 do not seem to be useful in management of patients with rectal cancer.
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Journal: Mol Ther. 2007 Jan;15(1):94-102.
Title: Identification of differentially expressed genes involved in the formation of multicellular tumor spheroids by HT-29 colon carcinoma cells.
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Title: A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo.
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Title: Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis.
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Title: Lapatinib: a dual inhibitor of EGFR and HER2 tyrosine kinase activity.
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Title: Long-term immunity elicited by antibody-cytokine fusion proteins protects against sequential challenge with murine mammary and colon malignancies.
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Title: Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
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Title: Increasing anticarcinoma activity of an anti-erbB2 recombinant immunotoxin by the addition of an anti-EpCAM sFv.
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Title: The clinical significance of circulating tumour cells in breast cancer and colorectal cancer patients.
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Title: Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer.
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Title: Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides.
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Journal: Neoplasia. 2007 Dec;9(12):1066-77.
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Title: Human epidermal growth factor receptor-2 and topoisomerase II alpha expressions in rectal cancer.
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Title: Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation.
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Title: Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway.
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Title: The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma.
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Title: A new molecular predictor of distant recurrence in ER-positive, HER2-negative breast cancer adds independent information to conventional clinical risk factors.
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Title: Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERalpha-positive breast cancer.
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Title: Expression of EGFR, HER2, phosphorylated ERK and phosphorylated MEK in colonic neoplasms of familial adenomatous polyposis patients.
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Title: Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.
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Title: The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells.
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Title: Targeted therapies and predictive markers in epithelial malignancies of the gastrointestinal tract.
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Title: Biomarkers for antitumor activity of bevacizumab in gastric cancer models.
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Title: Safety, efficacy and pharmacokinetics of neratinib (HKI-272) in Japanese patients with advanced solid tumors: a Phase 1 dose-escalation study.
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Title: Transcriptional upregulation of HER2 expression in the absence of HER2 gene amplification results in cetuximab resistance that is reversed by trastuzumab treatment.
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Title: MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle.
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Title: The relationship between the stromal mast cell number, microvessel density, c-erbB-2 staining and survival and prognostic factors in colorectal carcinoma.
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Title: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
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Title: KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung.
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Title: Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing.
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Title: A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.
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Title: Fatty acid synthase regulates proliferation and migration of colorectal cancer cells via HER2-PI3K/Akt signaling pathway.
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Title: Anti-HER-2 anti-CD3 bi-specific antibodies inhibit growth of HCT-116 colorectal carcinoma cells in vitro and in vivo.
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Title: Redirecting gene-modified T cells toward various cancer types using tagged antibodies.
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Title: Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.
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Title: Expression of EGFR, Her2 predict lymph node metastasis (LNM)-associated metastasis in colorectal cancer.
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Title: alpha-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation.
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Title: Analysis of PTEN, VEGF, HER2 and P53 status in determining colorectal cancer benefit from bevacizumab therapy.
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Journal: Gut. 2013 Apr;62(4):550-60.
Title: Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling.
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Title: Comprehensive fluorogenic derivatization-liquid chromatography/tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate.
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Title: Association of a common genetic variant of the IGF-1 gene with event-free survival in patients with HER2-positive breast cancer.
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Title: Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells.
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Title: HER3 overexpression and survival in solid tumors: a meta-analysis.
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Title: Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR antibodies: overcoming the mechanisms of cancer cell resistance.
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Title: miR-214 and hypoxia down-regulate Necl-2/CADM1 and enhance ErbB2/ErbB3 signaling.
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Title: Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers.
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Title: Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells.
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Title: The role of microRNA-200 in progression of human colorectal and breast cancer.
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Title: Phase 1 dose-escalation, pharmacokinetic, and cerebrospinal fluid distribution study of TAK-285, an investigational inhibitor of EGFR and HER2.
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Title: The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.
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Title: A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer.
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Title: Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.
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Title: Characterization of proapoptotic compounds from the bark of Garcinia oblongifolia.
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Title: HER2 status in colorectal cancer: its clinical significance and the relationship between HER2 gene amplification and expression.
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Title: Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independent of KRAS mutational status.
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Title: The advent of precision therapy in gastrointestinal malignancies: Targeting the human epidermal growth factor receptor family in colorectal and esophagogastric cancer.
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Title: [The differences between three distinct locations of colorectal cancers based on clinicopathological characteristics and molecular features].
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Journal: Oncogene. 2015 Jan 2;34(1):15-26.
Title: Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins.
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Title: Personalised cancer medicine.
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Title: 188Re-HYNIC-trastuzumab enhances the effect of apoptosis induced by trastuzumab in HER2-overexpressing breast cancer cells.
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Title: Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR.
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Title: A 21-year-old patient with a HER2-positive colorectal cancer.
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Journal: Metabolism. 2015 Mar;64(3 Suppl 1):S16-21.
Title: Biomarkers for personalized oncology: recent advances and future challenges.
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Title: Examination of HER3 targeting in cancer using monoclonal antibodies.
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Title: HER3 expression in primary colorectal cancer including corresponding metastases in lymph node and liver.
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Title: HER3 protein expression in relation to HER2 positivity in patients with primary colorectal cancer: clinical relevance and prognostic value.
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Title: A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol.
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Title: Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients.
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Journal: Digestion. 2015;91(4):294-302.
Title: Established and Potential Predictive Biomarkers in Gastrointestinal Cancer--c-Kit, Her2, Ras and Beyond.
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Title: Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells.
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Journal: Am Soc Clin Oncol Educ Book. 2015:e149-56.
Title: Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer.
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Title: Determination of Tumor Heterogeneity in Colorectal Cancers Using Heterogeneity Tissue Microarrays.
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Title: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
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Title: Gene expression profiling of laterally spreading tumors.
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Journal: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Sep;159(3):466-71.
Title: Comparison of the prevalence of KRAS-LCS6 polymorphism (rs61764370) within different tumour types (colorectal, breast, non-small cell lung cancer and brain tumours). A study of the Czech population.
Author: Uvirova, Magdalena|Simova, Jarmila|Kubova, Barbora|Dvorackova, Nina|Tomaskova, Hana|Sedivcova, Monika|Dite, Petr
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Journal: Clin Colorectal Cancer. 2015 Dec;14(4):203-18.
Title: Current and Future Approaches to Target the Epidermal Growth Factor Receptor and Its Downstream Signaling in Metastatic Colorectal Cancer.
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Title: Clinical significance of glycoprotein nonmetastatic B and its association with HER2 in breast cancer.
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Journal: J Hum Genet. 2015 Oct;60(10):589-96.
Title: Genetic mutations in human rectal cancers detected by targeted sequencing.
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Journal: PLoS One. 2015 Jul 17;10(7):e0133133.
Title: Bevacizumab in Combination with Modified FOLFOX6 in Heavily Pretreated Patients with HER2/Neu-Negative Metastatic Breast Cancer: A Phase II Clinical Trial.
Author: Li, Ting|Wang, Biyun|Wang, Zhonghua|Ragaz, Joseph|Zhang, Jian|Sun, Si|Cao, Jun|Lv, Fangfang|Wang, Leiping|Zhang, Sheng|Ni, Chen|Wu, Zhenhua|Xie, Jie|Hu, Xichun
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Title: ERBB2 emerges as a new target for colorectal cancer.
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Title: HER2 activating mutations are targets for colorectal cancer treatment.
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Journal: Oncoscience. 2015 Jul 1;2(6):581-4.
Title: Durable clinical benefit to trastuzumab and chemotherapy in a patient with metastatic colon adenocarcinoma harboring ERBB2 amplification.
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Title: Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array.
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Title: Does overexpression of HER-2 correlate with clinicopathological characteristics and prognosis in colorectal cancer? Evidence from a meta-analysis.
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Journal: Int J Mol Sci. 2015 Aug 17;16(8):19447-57.
Title: Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma.
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Journal: Oncotarget. 2015 Sep 22;6(28):26483-93.
Title: Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer.
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Journal: Oncol Rep. 2015 Nov;34(5):2768-75.
Title: Isolation and characterization of circulating micro(nano)vesicles in the plasma of colorectal cancer patients and their interactions with tumor cells.
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Title: Clonal origins and parallel evolution of regionally synchronous colorectal adenoma and carcinoma.
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Journal: J Nephrol. 2015 Dec;28(6):647-57.
Title: Renal toxicity of anticancer agents targeting HER2 and EGFR.
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Journal: Breast Cancer Res. 2015 Sep 17;17:128.
Title: Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion.
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Journal: Nature. 2015 Oct 8;526(7572):263-7.
Title: The genomic landscape of response to EGFR blockade in colorectal cancer.
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Journal: J Proteome Res. 2015 Dec 4;14(12):4995-5006.
Title: Integrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues.
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Journal: Mod Pathol. 2015 Nov;28(11):1481-91.
Title: Assessment of a HER2 scoring system for colorectal cancer: results from a validation study.
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Journal: Curr Cancer Drug Targets. 2015;15(8):703-15.
Title: Prognostic and Predictive Biomarkers in Colorectal Cancer. From the Preclinical Setting to Clinical Practice.
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Title: [Molecular phenotypes of colorectal cancer is critical in clinical individual treatment].
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Journal: Cancer Treat Rev. 2015 Dec;41(10):859-67.
Title: The use of combinations of monoclonal antibodies in clinical oncology.
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Journal: Cancer Biol Ther. 2015;16(12):1726-37.
Title: Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites.
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Journal: PLoS One. 2015 Nov 10;10(11):e0142487.
Title: Mutational Profiling Can Establish Clonal or Independent Origin in Synchronous Bilateral Breast and Other Tumors.
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Journal: Semin Oncol. 2015 Dec;42(6):896-908.
Title: Overcoming Resistance to Targeted Therapies in Cancer.
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Journal: Asian Pac J Cancer Prev. 2015;16(17):7671-4.
Title: Survey of HER2-neu Expression in Colonic Adenocarcinoma in the West of Iran.
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Journal: Gan To Kagaku Ryoho. 2015 Nov;42(12):1971-3.
Title: [A Case of a Submucosal Tumor-Like Gastric Cancer That Needed to Be Distinguished from Gastric Metastasis of Rectal Cancer].
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Title: [Companion Diagnostics for Solid Tumors].
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Journal: Gut. 2016 Aug;65(8):1296-305.
Title: Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer.
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Journal: Expert Opin Biol Ther. 2016;16(2):243-53.
Title: Pertuzumab in gastrointestinal cancer.
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Journal: Oncotarget. 2016 Jan 19;7(3):3453-60.
Title: HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer.
Author: Takegawa, Naoki|Yonesaka, Kimio|Sakai, Kazuko|Ueda, Hiroto|Watanabe, Satomi|Nonagase, Yoshikane|Okuno, Tatsuya|Takeda, Masayuki|Maenishi, Osamu|Tsurutani, Junji|Satoh, Taroh|Okamoto, Isamu|Nishio, Kazuto|Tamura, Takao|Nakagawa, Kazuhiko
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Journal: Mol Cancer Res. 2016 Mar;14(3):296-301.
Title: Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF.
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Journal: J Pathol. 2016 Mar;238(4):562-70.
Title: HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
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Title: Design and Synthesis of Near-Infrared Peptide for in Vivo Molecular Imaging of HER2.
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Journal: Oncol Rep. 2016 Feb;35(2):1091-100.
Title: Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins.
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Journal: Oncol Rep. 2016 Feb;35(2):1075-82.
Title: MiR-331-3p inhibits proliferation and promotes apoptosis by targeting HER2 through the PI3K/Akt and ERK1/2 pathways in colorectal cancer.
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Journal: ACS Nano. 2016 Jan 26;10(1):648-62.
Title: Engineering Chimeric Receptors To Investigate the Size- and Rigidity-Dependent Interaction of PEGylated Nanoparticles with Cells.
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Journal: J Clin Pathol. 2016 Sep;69(9):767-71.
Title: Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.
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Journal: Onco Targets Ther. 2016 Jan 12;9:287-93.
Title: WISP3 is highly expressed in a subset of colorectal carcinomas with a better prognosis.
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Journal: Acta Oncol. 2016 Jul;55(7):875-80.
Title: HER3 expression is correlated to distally located and low-grade colon cancer.
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Title: Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment.
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Journal: Middle East J Dig Dis. 2016 Jan;8(1):24-30.
Title: Human Epidermal Growth Factor Receptor Expression in Colorectal Cancer and Its Relationship with Clinicopathological Characteristics.
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Journal: Mol Med Rep. 2016 Apr;13(4):3514-20.
Title: Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer.
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Journal: PLoS One. 2016 Mar 18;11(3):e0151865.
Title: BRAF, PIK3CA, and HER2 Oncogenic Alterations According to KRAS Mutation Status in Advanced Colorectal Cancers with Distant Metastasis.
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Journal: Cancer. 2016 Jun 1;122(11):1689-96.
Title: Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/beta-catenin signaling pathway mutations.
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Journal: Expert Rev Anticancer Ther. 2016 May;16(5):557-71.
Title: Update on optimal treatment for metastatic colorectal cancer from the ACTG/AGITG expert meeting: ECCO 2015.
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Journal: J Hematol Oncol. 2016 Mar 24;9:29.
Title: Case report: mismatch repair proficiency and microsatellite stability in gastric cancer may not predict programmed death-1 blockade resistance.
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Journal: Clin Cancer Res. 2016 Jun 1;22(11):2659-67.
Title: Phase I Study of an AKT Inhibitor (MK-2206) Combined with Lapatinib in Adult Solid Tumors Followed by Dose Expansion in Advanced HER2+ Breast Cancer.
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Journal: J Gastrointest Oncol. 2016 Apr;7(Suppl 1):S55-61.
Title: Consensus and conflict in invasive micropapillary carcinoma: a case report and review of the literature.
Author: Lei, Li|Zhang, Huina|Zhang, Xinhai Bob|Lonser, Roland|Thompson, Kevin|Raza, Anwar
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Journal: Gastroenterology. 2016 Aug;151(2):278-287.e6.
Title: Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease.
Author: Yaeger, Rona|Shah, Manish A|Miller, Vincent A|Kelsen, Judith R|Wang, Kai|Heins, Zachary J|Ross, Jeffrey S|He, Yuting|Sanford, Eric|Yantiss, Rhonda K|Balasubramanian, Sohail|Stephens, Philip J|Schultz, Nikolaus|Oren, Moshe|Tang, Laura|Kelsen, David
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Journal: Int J Nanomedicine. 2016 Apr 1;11:1349-66.
Title: Theranostic multimodular potential of zinc-doped ferrite-saturated metal-binding protein-loaded novel nanocapsules in cancers.
Author: Kamalapuram, Sishir K|Kanwar, Rupinder K|Roy, Kislay|Chaudhary, Rajneesh|Sehgal, Rakesh|Kanwar, Jagat R
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Journal: Int J Biol Markers. 2016 Dec 23;31(4):e389-e394.
Title: Clinicopathological significance and diagnostic accuracy of HER2 immunohistochemistry in colorectal cancer: a meta-analysis.
Author: Pyo, Jung-Soo|Kang, Guhyun|Park, Kyeongmee
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Journal: Lancet Oncol. 2016 Jun;17(6):738-746.
Title: Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial.
Author: Sartore-Bianchi, Andrea|Trusolino, Livio|Martino, Cosimo|Bencardino, Katia|Lonardi, Sara|Bergamo, Francesca|Zagonel, Vittorina|Leone, Francesco|Depetris, Ilaria|Martinelli, Erika|Troiani, Teresa|Ciardiello, Fortunato|Racca, Patrizia|Bertotti, Andrea|Sirav
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Journal: Lancet Oncol. 2016 Jun;17(6):685-686.
Title: Targeting HER2: precision oncology for colorectal cancer.
Author: Schmoll, Hans-Joachim
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Journal: Ann Oncol. 2016 Apr;27 Suppl 1:i53-i57.
Title: Mucinous epithelial ovarian carcinoma.
Author: Perren, T J
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Journal: Carcinogenesis. 2016 Jul;37(7):731-739.
Title: Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Author: Tao, Yun|Messer, Jeannette S|Goss, Kathleen H|Hart, John|Bissonnette, Marc|Chang, Eugene B
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Journal: Sci Rep. 2016 Jun 3;6:26997.
Title: Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue.
Author: Cederbye, Camilla Natasha|Palshof, Jesper Andreas|Hansen, Tine Plato|Duun-Henriksen, Anne Katrine|Linnemann, Dorte|Stenvang, Jan|Nielsen, Dorte Lisbet|Brunner, Nils|Viuff, Birgitte Martine
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Journal: Nucleic Acids Res. 2016 Jul 27;44(13):6274-86.
Title: Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants.
Author: Xi, Ruibin|Lee, Semin|Xia, Yuchao|Kim, Tae-Min|Park, Peter J
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Journal: BMC Cancer. 2016 Jun 13;16:366.
Title: PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study.
Author: Kuramochi, Hidekazu|Nakamura, Ayako|Nakajima, Go|Kaneko, Yuka|Araida, Tatsuo|Yamamoto, Masakazu|Hayashi, Kazuhiko
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Journal: Dig Dis. 2016;34(5):574-9.
Title: Therapeutic Strategies in Diseases of the Digestive Tract - 2015 and Beyond Targeted Therapies in Colon Cancer Today and Tomorrow.
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Journal: Cancer J. 2016 May-Jun;22(3):149-55.
Title: Spectrum of Gene Mutations in Colorectal Cancer: Implications for Treatment.
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Journal: Pharmacol Ther. 2016 Oct;166:71-83.
Title: Preclinical and clinical studies on afatinib in monotherapy and in combination regimens: Potential impact in colorectal cancer.
Author: De Pauw, I|Wouters, A|Van den Bossche, J|Peeters, M|Pauwels, P|Deschoolmeester, V|Vermorken, J B|Lardon, F
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Journal: Cancer Med. 2016 Sep;5(9):2249-60.
Title: Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance).
Author: Hatch, Ace J|Sibley, Alexander B|Starr, Mark D|Brady, J Chris|Jiang, Chen|Jia, Jingquan|Bowers, Daniel L|Pang, Herbert|Owzar, Kouros|Niedzwiecki, Donna|Innocenti, Federico|Venook, Alan P|Hurwitz, Herbert I|Nixon, Andrew B
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Journal: Oncotarget. 2016 Oct 18;7(42):69060-69074.
Title: HER-2 inhibition in gastric and colorectal cancers: tangible achievements, novel acquisitions and future perspectives.
Author: Fanotto, Valentina|Ongaro, Elena|Rihawi, Karim|Avallone, Antonio|Silvestris, Nicola|Fornaro, Lorenzo|Vasile, Enrico|Antonuzzo, Lorenzo|Leone, Francesco|Rosati, Gerardo|Giuliani, Francesco|Bordonaro, Roberto|Scartozzi, Mario|De Maglio, Giovanna|Negri, Fran
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Journal: Clujul Med. 2016;89(3):378-83.
Title: Tumor markers used in monitoring the tumor recurrence in patients with colorectal cancer.
Author: Burz, Claudia|Aziz, Ben Youssef Mohamed|Balacescu, Loredana|Lelutiu, Luminita|Buiga, Rares|Samasca, Gabriel|Irimie, Alexandru|Lisencu, Cosmin
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Journal: Med Oncol. 2016 Oct;33(10):106.
Title: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author: Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam
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Journal: World J Gastroenterol. 2016 Aug 14;22(30):6944-54.
Title: Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
Author: Lo Nigro, Cristiana|Ricci, Vincenzo|Vivenza, Daniela|Granetto, Cristina|Fabozzi, Teresa|Miraglio, Emanuela|Merlano, Marco C
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Journal: J Hematol Oncol. 2016 Aug 31;9(1):76.
Title: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway.
Author: Liu, Jing|Pan, Changqie|Guo, Lihong|Wu, Mengwan|Guo, Jing|Peng, Sheng|Wu, Qianying|Zuo, Qiang
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Journal: Cancers (Basel). 2016 Sep 1;8(9). pii: cancers8090082.
Title: Wnt Drug Discovery: Weaving Through the Screens, Patents and Clinical Trials.
Author: Lu, Benjamin|Green, Brooke A|Farr, Jacqueline M|Lopes, Flavia C M|Van Raay, Terence J
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Journal: Gastroenterol Res Pract. 2016;2016:3481578.
Title: Prognostic Impact of mRNA Expression Levels of HER1-4 (ERBB1-4) in Patients with Locally Advanced Rectal Cancer.
Author: Kripp, Melanie|Merx, Kirsten|Wirtz, Ralph Markus|Gaiser, Timo|Eidt, Sebastian|Schwaab, Juliana|Post, Stefan|Wenz, Frederik|Hochhaus, Andreas|Hofheinz, Ralf-Dieter|Erben, Philipp
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Journal: Cold Spring Harb Mol Case Stud. 2016 Sep;2(5):a001016.
Title: Testing ERBB2 p.L755S kinase domain mutation as a druggable target in a patient with advanced colorectal cancer.
Author: Aung, Kyaw L|Stockley, Tracy L|Serra, Stefano|Kamel-Reid, Suzanne|Bedard, Philippe L|Siu, Lillian L
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Journal: Tumori. 2016 Dec 1;102(6):541-547.
Title: How the lab is changing our view of colorectal cancer.
Author: Cremolini, Chiara|Pietrantonio, Filippo
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Journal: Am J Cancer Res. 2016 Aug 1;6(8):1609-23. eCollection 2016.
Title: A perspective on anti-EGFR therapies targeting triple-negative breast cancer.
Author: Nakai, Katsuya|Hung, Mien-Chie|Yamaguchi, Hirohito
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Journal: World J Gastroenterol. 2016 Sep 21;22(35):7926-37.
Title: HER2 aberrations and heterogeneity in cancers of the digestive system: Implications for pathologists and gastroenterologists.
Author: Fusco, Nicola|Bosari, Silvano
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Journal: Oncologist. 2016 Nov;21(11):1306-1314.
Title: Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer.
Author: Rankin, Andrew|Klempner, Samuel J|Erlich, Rachel|Sun, James X|Grothey, Axel|Fakih, Marwan|George, Thomas J Jr|Lee, Jeeyun|Ross, Jeffrey S|Stephens, Philip J|Miller, Vincent A|Ali, Siraj M|Schrock, Alexa B
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Journal: Expert Opin Biol Ther. 2016 Dec;16(12):1549-1555.
Title: The prospect of patritumab for treating non-small cell lung cancer.
Author: Horinouchi, Hidehito
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Journal: BMC Cancer. 2016 Nov 7;16(1):855.
Title: Frequency of Her2/neu expression in colorectal adenocarcinoma: a study from developing South Asian Country.
Author: Shabbir, Asma|Mirza, Talat|Khalid, Abdullah Bin|Qureshi, Muhammad Asif|Asim, Sadaf Ahmed
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Journal: Int J Surg Case Rep. 2016;29:133-136.
Title: A case report of chylous ascites after gastric bypass for morbid obesity.
Author: Capristo, Esmeralda|Spuntarelli, Valerio|Treglia, Giorgio|Arena, Vincenzo|Giordano, Alessandro|Mingrone, Geltrude
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Journal: Curr Mol Med. 2016;16(9):829-839.
Title: Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features.
Author: Lee, H S|Park, K U|Kim, D-W|Lhn, M H|Kim, W H|Seo, A N|Chang, H E|Nam, S K|Lee, S Y|Oh, H-K|Kang, S-B
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Journal: Genome Med. 2016 Dec 22;8(1):136.
Title: Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine.
Author: Nagahashi, Masayuki|Wakai, Toshifumi|Shimada, Yoshifumi|Ichikawa, Hiroshi|Kameyama, Hitoshi|Kobayashi, Takashi|Sakata, Jun|Yagi, Ryoma|Sato, Nobuaki|Kitagawa, Yuko|Uetake, Hiroyuki|Yoshida, Kazuhiro|Oki, Eiji|Kudo, Shin-Ei|Izutsu, Hiroshi|Kodama, Keisuke|
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Journal: Curr Oncol. 2016 Dec;23(6):e571-e575.
Title: Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Author: Sheffield, B S|Tessier-Cloutier, B|Li-Chang, H|Shen, Y|Pleasance, E|Kasaian, K|Li, Y|Jones, S J M|Lim, H J|Renouf, D J|Huntsman, D G|Yip, S|Laskin, J|Marra, M|Schaeffer, D F
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Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):1800-1802.
Title: [A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy].
Author: Yagi, Ryoma|Shimada, Yoshifumi|Miura, Kohei|Tajima, Yosuke|Okamura, Takuma|Nakano, Masato|Ichikawa, Hiroshi|Nagahashi, Masayuki|Sakata, Jun|Kobayashi, Takashi|Kameyama, Hitoshi|Wakai, Toshifumi|Nogami, Hitoshi|Maruyama, Satoshi|Takii, Yasumasa
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Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):2047-2049.
Title: [Right Hemi-Colectomy for a Metastatic Transverse Colon Tumor from Breast Cancer Following Bilateral Breast Cancer Resection - A Case Report].
Author: Okamura, Shu|Yanagisawa, Tetsu|Ohishi, Kazuhito|Murata, Kohei|Nushijima, Yoichiro|Hamano, Rie|Fukuchi, Nariaki|Ebisui, Chikara|Yokouchi, Hideoki|Kinuta, Masakatsu
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Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):2307-2309.
Title: [A Case of Metastatic Colorectal Cancer with HER2 Overexpression/Amplification].
Author: Matsumoto, Akio|Shimada, Yoshifumi|Yagi, Ryoma|Miura, Kohei|Tajima, Yosuke|Okamura, Takuma|Nakano, Masato|Kameyama, Hitoshi|Nogami, Hitoshi|Maruyama, Satoshi|Takii, Yasumasa|Ichikawa, Hiroshi|Sakata, Jun|Kobayashi, Takashi|Wakai, Toshifumi
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Journal: Artif Cells Nanomed Biotechnol. 2017 May;45(3):649-654.
Title: Structure-based design of peptides against HER2 with cytotoxicity on colon cancer.
Author: Cha, Nier|Han, Xiuhua|Jia, Baoqing|Liu, Yanheng|Wang, Xiaoli|Gao, Yanwei|Ren, Jun
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Journal: JAMA Oncol. 2017 Jun 1;3(6):767-773.
Title: Association of Proton Pump Inhibitors and Capecitabine Efficacy in Advanced Gastroesophageal Cancer: Secondary Analysis of the TRIO-013/LOGiC Randomized Clinical Trial.
Author: Chu, Michael P|Hecht, J Randolph|Slamon, Dennis|Wainberg, Zev A|Bang, Yung-Jue|Hoff, Paulo M|Sobrero, Alberto|Qin, Shukui|Afenjar, Karen|Houe, Vincent|King, Karen|Koski, Sheryl|Mulder, Karen|Hiller, Julie Price|Scarfe, Andrew|Spratlin, Jennifer|Huang, Yin
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Journal: Biomed Pharmacother. 2017 Jan;85:418-424.
Title: Simvastatin inhibits tumor angiogenesis in HER2-overexpressing human colorectal cancer.
Author: Li, Gang|Zheng, Junhua|Xu, Bin|Ling, Jie|Qiu, Wei|Wang, Yongbing
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Journal: Int J Cancer. 2017 Apr 1;140(7):1653-1661.
Title: Copy number variations in DCC/18q and ERBB2/17q are associated with disease-free survival in microsatellite stable colon cancer.
Author: Sefrioui, David|Vermeulin, Thomas|Blanchard, France|Chapusot, Caroline|Beaussire, Ludivine|Armengol-Debeir, Laura|Sesboue, Richard|Gangloff, Alice|Hebbar, Mohamed|Copin, Marie-Christine|Houivet, Estelle|Schwarz, Lilian|Clatot, Florian|Tuech, Jean-Jacques|
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Journal: Oncotarget. 2017 Jan 17;8(3):4277-4288.
Title: Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Author: Bosch-Vilaro, Albert|Jacobs, Bart|Pomella, Valentina|Abbasi Asbagh, Layka|Kirkland, Richard|Michel, Joe|Singh, Sharat|Liu, Xinjun|Kim, Phillip|Weitsman, Gregory|Barber, Paul R|Vojnovic, Borivoj|Ng, Tony|Tejpar, Sabine
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Journal: J Natl Compr Canc Netw. 2017 Jan;15(1):3-8.
Title: Prolonged Response to HER2-Directed Therapy in a Patient With HER2-Amplified, Rapidly Progressive Metastatic Colorectal Cancer.
Author: Parikh, Aparna|Atreya, Chloe|Korn, W Michael|Venook, Alan P
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Journal: Curr Med Res Opin. 2017 Apr;33(4):749-759.
Title: Targeting the PD-1 pathway: a new hope for gastrointestinal cancers.
Author: Bilgin, Burak|Sendur, Mehmet A N|Bulent Akinci, Muhammed|Sener Dede, Didem|Yalcin, Bulent
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Journal: Future Oncol. 2017 Apr;13(10):919-934.
Title: Translating genomic profiling to gastrointestinal cancer treatment.
Author: Harada, Kazuto|Mizrak Kaya, Dilsa|Shimodaira, Yusuke|Song, Shumei|Baba, Hideo|Ajani, Jaffer A
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Journal: Int J Radiat Oncol Biol Phys. 2017 Feb 1;97(2):246-253.
Title: Multi-institutional Nomogram Predicting Survival Free From Salvage Whole Brain Radiation After Radiosurgery in Patients With Brain Metastases.
Author: Gorovets, Daniel|Ayala-Peacock, Diandra|Tybor, David J|Rava, Paul|Ebner, Daniel|Cielo, Deus|Noren, Georg|Wazer, David E|Chan, Michael|Hepel, Jaroslaw T
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Journal: World J Gastroenterol. 2017 Feb 21;23(7):1233-1240.
Title: High levels of serum platelet-derived growth factor-AA and human epidermal growth factor receptor-2 are predictors of colorectal cancer liver metastasis.
Author: Pan, Hong-Da|Peng, Yi-Fan|Xiao, Gang|Gu, Jin
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Journal: J Gastrointest Oncol. 2017 Feb;8(1):199-212.
Title: Current companion diagnostics in advanced colorectal cancer; getting a bigger and better piece of the pie.
Author: Loree, Jonathan M|Kopetz, Scott|Raghav, Kanwal P S
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Journal: Clin Colorectal Cancer. 2017 Dec;16(4):247-251.
Title: HER2 as an Emerging Oncotarget for Colorectal Cancer Treatment After Failure of Anti-Epidermal Growth Factor Receptor Therapy.
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Journal: Expert Opin Ther Pat. 2017 May;27(5):527-538.
Title: Methods of selecting combination therapy for colorectal cancer patients: a patent evaluation of US20160025730A1.
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Journal: Cancer Discov. 2017 Jun;7(6):OF12.
Title: Profiling Differential Responses to Pan-HER Inhibition.
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Journal: Oncology (Williston Park). 2017 Apr 15;31(4):301-12.
Title: Molecular Testing to Optimize and Personalize Decision Making in the Management of Colorectal Cancer.
Author: Al-Hajeili, Marwan|Shields, Anthony F|Hwang, Jimmy J|Wadlow, Raymond C|Marshall, John L
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Journal: Acta Oncol. 2017 May;56(5):639-645.
Title: Risk factors for brain metastases in patients with metastatic colorectal cancer.
Author: Christensen, Troels Dreier|Palshof, Jesper Andreas|Larsen, Finn Ole|Hogdall, Estrid|Poulsen, Tim Svenstrup|Pfeiffer, Per|Jensen, Benny Vittrup|Yilmaz, Mette Karen|Christensen, Ib Jarle|Nielsen, Dorte
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Journal: Sci Rep. 2017 May 4;7(1):1502.
Title: Rationally co-targeting divergent pathways in KRAS wild-type colorectal cancers by CANscript technology reveals tumor dependence on Notch and Erbb2.
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Journal: Oncotarget. 2017 Jun 20;8(25):41401-41411.
Title: Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells.
Author: Hong, Eun-Hye|Heo, Eun-Young|Song, Jae-Hyoung|Kwon, Bo-Eun|Lee, Jae-Young|Park, Yaejeong|Kim, Jinwoong|Chang, Sun-Young|Chin, Young-Won|Jeon, Sang-Min|Ko, Hyun-Jeong
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Journal: Target Oncol. 2017 Jun;12(3):265-275.
Title: What We Know About Stage II and III Colon Cancer: It's Still Not Enough.
Author: Puccini, Alberto|Berger, Martin D|Zhang, Wu|Lenz, Heinz-Josef
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Journal: J Surg Oncol. 2017 Nov;116(6):706-715.
Title: Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients.
Author: Handa, Tadashi|Katayama, Ayaka|Yokobori, Takehiko|Yamane, Arito|Horiguchi, Jun|Kawabata-Iwakawa, Reika|Rokudai, Susumu|Bao, Pinjie|Gombodorj, Navchaa|Altan, Bolag|Kaira, Kyoichi|Asao, Takayuki|Kuwano, Hiroyuki|Nishiyama, Masahiko|Oyama, Tetsunari
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Journal: J Med Econ. 2017 Oct;20(10):1018-1023.
Title: Cost drivers for breast, lung, and colorectal cancer care in a commercially insured population over a 6-month episode: an economic analysis from a health plan perspective.
Author: Sagar, Bhuvana|Lin, Yu Shen|Castel, Liana D
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Journal: World J Stem Cells. 2017 May 26;9(5):77-88.
Title: Next-generation sequencing traces human induced pluripotent stem cell lines clonally generated from heterogeneous cancer tissue.
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Journal: JAMA Oncol. 2017 Nov 1;3(11):1546-1553.
Title: Genomic Profiling of Small-Bowel Adenocarcinoma.
Author: Schrock, Alexa B|Devoe, Craig E|McWilliams, Robert|Sun, James|Aparicio, Thomas|Stephens, Philip J|Ross, Jeffrey S|Wilson, Richard|Miller, Vincent A|Ali, Siraj M|Overman, Michael J
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Journal: Breast Cancer Res. 2017 Jun 19;19(1):71.
Title: Evaluation of invasive breast cancer samples using a 12-chemokine gene expression score: correlation with clinical outcomes.
Author: Prabhakaran, Sangeetha|Rizk, Victoria T|Ma, Zhenjun|Cheng, Chia-Ho|Berglund, Anders E|Coppola, Dominico|Khalil, Farah|Mule, James J|Soliman, Hatem H
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Journal: Mol Cancer. 2017 Jul 6;16(1):116.
Title: Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies.
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Journal: J Gastrointest Oncol. 2017 Jun;8(3):387-404.
Title: Personalized and precision medicine: integrating genomics into treatment decisions in gastrointestinal malignancies.
Author: Au, Trang H|Wang, Kai|Stenehjem, David|Garrido-Laguna, Ignacio
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Journal: J Gastrointest Oncol. 2017 Jun;8(3):405-417.
Title: Predictive and prognostic biomarkers in personalized gastrointestinal cancer treatment.
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Journal: J Gastrointest Oncol. 2017 Jun;8(3):499-512.
Title: Primary and acquired resistance to biologic therapies in gastrointestinal cancers.
Author: Lubner, Sam J|Uboha, Nataliya V|Deming, Dustin A
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Journal: J Transl Med. 2017 Aug 1;15(1):167.
Title: Comparative analysis of the EGFR, HER2, c-MYC, and MET variations in colorectal cancer determined by three different measures: gene copy number gain, amplification status and the 2013 ASCO/CAP guideline criterion for HER2 testing of breast cancer.
Author: Kwak, Yoonjin|Yun, Sumi|Nam, Soo Kyung|Seo, An Na|Lee, Kyu Sang|Shin, Eun|Oh, Heung-Kwon|Kim, Duck Woo|Kang, Sung Bum|Kim, Woo Ho|Lee, Hye Seung
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Journal: J Natl Compr Canc Netw. 2017 Aug;15(8):983-988.
Title: Neoadjuvant Treatment With Trastuzumab and FOLFOX Induces a Complete Pathologic Response in a Metastatic ERBB2 (HER2)-Amplified Duodenal Cancer.
Author: Hamad, Ahmad|Singhi, Aatur D|Bahary, Nathan|McGrath, Kevin|Amarin, Rula|Zeh, Herbert J|Zureikat, Amer H
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Journal: Ther Adv Med Oncol. 2017 Aug;9(8):551-564.
Title: Recent developments in the treatment of metastatic colorectal cancer.
Author: Loree, Jonathan M|Kopetz, Scott
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Journal: Cancer Chemother Pharmacol. 2017 Oct;80(4):807-813.
Title: Depth of response predicts the clinical outcome of advanced HER2-positive gastric cancer to trastuzumab-based first-line chemotherapy.
Author: Kadowaki, Shigenori|Masuishi, Toshiki|Eto, Tetsuya|Narita, Yukiya|Taniguchi, Hiroya|Ura, Takashi|Ando, Masashi|Tajika, Masahiro|Niwa, Yasumasa|Yatabe, Yasushi|Muro, Kei
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Journal: Oncotarget. 2017 Jul 10;8(40):68026-68037.
Title: Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.
Author: Kong, Say Li|Liu, Xingliang|Suhaimi, Nur-Afidah Mohamed|Koh, Kenneth Jia Hao|Hu, Min|Lee, Daniel Yoke San|Cima, Igor|Phyo, Wai Min|Lee, Esther Xing Wei|Tai, Joyce A|Foong, Yu Miin|Vo, Jess Honganh|Koh, Poh Koon|Zhang, Tong|Ying, Jackie Y|Lim, Bing|Tan, Mi
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Journal: Br J Cancer. 2017 Dec 5;117(12):1819-1827.
Title: Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.
Author: Lievre, Astrid|Ouine, Berengere|Canet, Jim|Cartier, Aurelie|Amar, Yael|Cacheux, Wulfran|Mariani, Odette|Guimbaud, Rosine|Selves, Janick|Lecomte, Thierry|Guyetant, Serge|Bieche, Ivan|Berger, Frederique|de Koning, Leanne
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Journal: Onco Targets Ther. 2017 Nov 3;10:5281-5288.
Title: PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells.
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Journal: Monoclon Antib Immunodiagn Immunother. 2017 Dec;36(6):287-290.
Title: Establishment of H2Mab-119, an Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody, Against Pancreatic Cancer.
Author: Yamada, Shinji|Itai, Shunsuke|Nakamura, Takuro|Chang, Yao-Wen|Harada, Hiroyuki|Suzuki, Hiroyoshi|Kaneko, Mika K|Kato, Yukinari
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Journal: Oncotarget. 2017 Aug 24;8(55):93567-93579.
Title: Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.
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Journal: Oncotarget. 2017 Sep 27;8(62):105072-105080.
Title: Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.
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Journal: Oncotarget. 2016 Aug 19;8(65):108463-108479.
Title: Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers.
Author: Bon, Giulia|Loria, Rossella|Amoreo, Carla Azzurra|Verdina, Alessandra|Sperduti, Isabella|Mastrofrancesco, Arianna|Soddu, Silvia|Diodoro, Maria Grazia|Mottolese, Marcella|Todaro, Matilde|Stassi, Giorgio|Milella, Michele|De Maria, Ruggero|Falcioni, Rita
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Journal: Gan To Kagaku Ryoho. 2017 Nov;44(12):1871-1873.
Title: [A Case of Synchronous Quadruple Cancers Treated with Neoadjuvant Chemotherapy Followed by Surgery].
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Journal: Semin Oncol. 2017 Jul 4. pii: S0093-7754(17)30056-8.
Title: Biomarker-driven and molecular targeted therapies for colorectal cancers.
Author: Schirripa, Marta|Cohen, Stacey A|Battaglin, Francesca|Lenz, Heinz-Josef
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Journal: Clin Colorectal Cancer. 2018 Mar;17(1):80-83.
Title: Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer.
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Journal: Mol Cancer Res. 2018 Mar;16(3):486-495.
Title: Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.
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Journal: Clin Cancer Res. 2018 Feb 15;24(4):794-806.
Title: Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies.
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Journal: Lancet Gastroenterol Hepatol. 2018 Mar;3(3):162-171.
Title: Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2-3 randomised trial.
Author: Adams, Richard|Brown, Ewan|Brown, Louise|Butler, Rachel|Falk, Stephen|Fisher, David|Kaplan, Richard|Quirke, Phil|Richman, Susan|Samuel, Leslie|Seligmann, Jenny|Seymour, Matt|Shiu, Kai Keen|Wasan, Harpreet|Wilson, Richard|Maughan, Tim
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Journal: Monoclon Antib Immunodiagn Immunother. 2018 Feb;37(1):59-62.
Title: Development of an Anti-HER2 Monoclonal Antibody H2Mab-139 Against Colon Cancer.
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Journal: Oncogene. 2018 Mar;37(12):1576-1593.
Title: BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.
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Journal: Oncologist. 2018 Apr;23(4):474-477.
Title: Trastuzumab Plus Pertuzumab Resistance Does Not Preclude Response to Lapatinib Plus Trastuzumab in HER2-Amplified Colorectal Cancer.
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Journal: Cancer. 2018 Apr 1;124(7):1358-1373.
Title: Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.
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Journal: J Cancer. 2018 Jan 1;9(2):358-366.
Title: Clinical Significance of Glycoprotein Non-metastatic B and Its Association with EGFR/HER2 in Gastrointestinal Cancer.
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Journal: Cancer Res Treat. 2018 Jan 17. pii: crt.2017.487.
Title: Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer.
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Journal: ESMO Open. 2018 Jan 10;3(1):e000299.
Title: Sequential HER2 blockade as effective therapy in chemorefractory, HER2 gene-amplified, RAS wild-type, metastatic colorectal cancer: learning from a clinical case.
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Journal: Hum Pathol. 2018 Jul;77:1-10.
Title: The importance of EGFR as a biomarker in molecular apocrine breast cancer.
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Journal: Oncotarget. 2017 Dec 15;9(3):3394-3405.
Title: Copy number profiles of paired primary and metastatic colorectal cancers.
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Journal: Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: mcs.a002535.
Title: Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases.
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Journal: Clin Drug Investig. 2018 Jun;38(6):553-562.
Title: First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Author: Moiseyenko, Vladimir M|Moiseyenko, Fedor V|Yanus, Grigoriy A|Kuligina, Ekatherina Sh|Sokolenko, Anna P|Bizin, Ilya V|Kudriavtsev, Alexey A|Aleksakhina, Svetlana N|Volkov, Nikita M|Chubenko, Vyacheslav A|Kozyreva, Kseniya S|Kramchaninov, Mikhail M|Zhuravle
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Journal: Surg Oncol Clin N Am. 2018 Apr;27(2):349-365.
Title: Clinical Trials and Progress in Metastatic Colon Cancer.
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Journal: Oncotarget. 2018 Jan 31;9(13):11322-11335.
Title: Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells.
Author: Hutt, Meike|Fellermeier-Kopf, Sina|Seifert, Oliver|Schmitt, Lisa C|Pfizenmaier, Klaus|Kontermann, Roland E
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Journal: Methods Mol Biol. 2018;1765:281-297.
Title: Molecular Testing for the Treatment of Advanced Colorectal Cancer: An Overview.
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Journal: Ann Oncol. 2018 May 1;29(5):1108-1119.
Title: Targeting the human epidermal growth factor receptor 2 (HER2) oncogene in colorectal cancer.
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Journal: J Exp Clin Cancer Res. 2018 Apr 17;37(1):84.
Title: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.
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Journal: Biomed Pharmacother. 2018 Jul;103:755-766.
Title: The role of Her2-Nrf2 axis in induction of oxaliplatin resistance in colon cancer cells.
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Journal: J Natl Cancer Inst. 2018 Apr 27. pii: 4989438.
Title: Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
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Journal: Sci Rep. 2018 May 8;8(1):7238.
Title: Molecular targets of Chinese herbs: a clinical study of metastatic colorectal cancer based on network pharmacology.
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Journal: Curr Treat Options Oncol. 2018 May 11;19(6):29.
Title: Promising New Agents for Colorectal Cancer.
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Journal: Oncotarget. 2018 Apr 17;9(29):20761-20768.
Title: Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience.
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Journal: Clin Cancer Res. 2018 Aug 1;24(15):3528-3538.
Title: The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 21,807 Advanced Cancer Patients.
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Journal: Inflamm Bowel Dis. 2018 Jul 12;24(8):1780-1790.
Title: Distinct Histopathologic and Molecular Alterations in Inflammatory Bowel Disease-Associated Intestinal Adenocarcinoma: c-MYC Amplification is Common and Associated with Mucinous/Signet Ring Cell Differentiation.
Author: Hartman, Douglas J|Binion, David G|Regueiro, Miguel D|Miller, Caitlyn|Herbst, Cameron|Pai, Reetesh K
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Journal: Oncotarget. 2018 May 8;9(35):23960-23974.
Title: Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.
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Title: Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.
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Journal: Med Oncol. 2018 May 31;35(7):101.
Title: Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping.
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Journal: Saudi J Gastroenterol. 2018 Sep-Oct;24(5):301-306.
Title: Correlated non-nuclear COX2 and low HER2 expression confers a good prognosis in colorectal cancer.
Author: Zhou, Fei-Fei|Huang, Rong|Jiang, Jun|Zeng, Xiao-Hong|Zou, Shu-Qian
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Journal: Clin Breast Cancer. 2018 Oct;18(5):e1149-e1163.
Title: Inducing or Preventing Subsequent Malignancies for Breast Cancer Survivors? Double-edged Sword of Estrogen Receptor and Progesterone Receptor.
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Title: Colorectal Cancer Stratification in the Routine Clinical Pathway: A District General Hospital Experience.
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Journal: Cancer Cell. 2018 Jul 9;34(1):148-162.e7.
Title: Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer.
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Journal: Expert Rev Anticancer Ther. 2018 Oct;18(10):991-1006.
Title: Targeted therapy for metastatic colorectal cancer.
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Journal: Cancer Prev Res (Phila). 2018 Jul 25. pii: 1940-6207.CAPR-18-0084.
Title: Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression.
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Journal: Free Radic Biol Med. 2018 Oct;126:41-54.
Title: Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability.
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Journal: Virchows Arch. 2018 Oct;473(4):413-423.
Title: HER2 status in patients with residual rectal cancer after preoperative chemoradiotherapy: the relationship with molecular results and clinicopathologic features.
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Title: Current and future therapies for targeting HER2 mutations in gastrointestinal cancer.
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Journal: Curr Probl Cancer. 2018 Jul 19. pii: S0147-0272(17)30139-3.
Title: HER2: An emerging target in colorectal cancer.
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Journal: J Cancer Res Clin Oncol. 2018 Aug 31. pii: 10.1007/s00432-018-2742-1.
Title: The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing.
Author: Zou, Shuang-Mei|Li, Wei-Hua|Wang, Wen-Miao|Li, Wen-Bin|Shi, Su-Sheng|Ying, Jian-Ming|Lyu, Ning
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Journal: J Cell Physiol. 2018 Sep 6.
Title: PTPH1 immunohistochemical expression and promoter methylation in breast cancer patients from India: A retrospective study.
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Journal: J Cancer Res Clin Oncol. 2018 Sep 10. pii: 10.1007/s00432-018-2744-z.
Title: Variability in HER2 expression between primary colorectal cancer and corresponding metastases.
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Journal: Clin Colorectal Cancer. 2018 Jul 17. pii: S1533-0028(18)30133-6.
Title: Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
Author: Khan, Maliha|Loree, Jonathan M|Advani, Shailesh M|Ning, Jing|Li, Wen|Pereira, Allan A L|Lam, Michael|Raghav, Kanwal|Morris, Van K|Broaddus, Russell|Maru, Dipen|Overman, Michael J|Kopetz, Scott
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Journal: Biochem Biophys Res Commun. 2018 Sep 11. pii: S0006-291X(18)31906-5.
Title: SPECT/CT imaging of HER2 expression in colon cancer-bearing nude mice using (125)I-Herceptin.
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Journal: Am Soc Clin Oncol Educ Book. 2018 May 23;(38):231-238.
Title: Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer.
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Journal: J Breast Cancer. 2018 Sep;21(3):288-296.
Title: High RNA-binding Motif Protein 3 Expression Is Associated with Improved Clinical Outcomes in Invasive Breast Cancer.
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Journal: Int J Cancer. 2018 Oct 10.
Title: ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in Early Stage Gallbladder Cancer.
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Journal: Pol J Pathol. 2018;69(2):143-149.
Title: Association between Her2/neu status in colorectal carcinoma and clinicopathological features: a retrospective study using whole - tissue sections.
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Journal: Oncologist. 2018 Oct 29. pii: theoncologist.2018-0152.
Title: Enrichment of HER2 Amplification in Brain Metastases from Primary Gastrointestinal Malignancies.
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