Literatures

Primary Site >> Biliary tract Cancer

Gene >> ERBB2

1.
Journal:	Am J Clin Pathol. 1992 May;97(5 Suppl 1):S53-61.
Title:	Immunoreactivity for c-erbB-2 oncopeptide in benign and malignant diseases of the liver.
Author:	Brunt, E M\|Swanson, P E
PMID:	1374219

2.
Journal:	J Pathol. 1996 Feb;178(2):140-5.
Title:	Overexpression of different members of the type 1 growth factor receptor family and their association with cell proliferation in periampullary carcinoma.
Author:	Vaidya, P\|Kawarada, Y\|Higashiguchi, T\|Yoshida, T\|Sakakura, T\|Yatani, R
PMID:	8683379

3.
Journal:	J Dermatol. 1996 Mar;23(3):191-5.
Title:	Hereditary onset of multiple seborrheic keratoses: a variant of Leser Trelat sign?
Author:	Yamamoto, T\|Yokoyama, A
PMID:	8935630

4.
Journal:	Am J Pathol. 1997 Dec;151(6):1685-94.
Title:	NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia.
Author:	Sirica, A E\|Radaeva, S\|Caran, N
PMID:	9403719

5.
Journal:	Hepatology. 1998 Apr;27(4):974-82.
Title:	Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study.
Author:	Ashida, K\|Terada, T\|Kitamura, Y\|Kaibara, N
PMID:	9537436

6.
Journal:	Hepatology. 1999 May;29(5):1453-62.
Title:	Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma.
Author:	Radaeva, S\|Ferreira-Gonzalez, A\|Sirica, A E
PMID:	10216129

7.
Journal:	Pathol Res Pract. 2001;197(2):95-100.
Title:	Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma.
Author:	Ito, Y\|Takeda, T\|Sasaki, Y\|Sakon, M\|Yamada, T\|Ishiguro, S\|Imaoka, S\|Tsujimoto, M\|Higashiyama, S\|Monden, M\|Matsuura, N
PMID:	11261824

8.
Journal:	J Gastroenterol Hepatol. 2001 Apr;16(4):363-72.
Title:	Biliary cancer growth factor pathways, cyclo-oxygenase-2 and potential therapeutic strategies.
Author:	Sirica, A E\|Lai, G H\|Zhang, Z
PMID:	11357901

9.
Journal:	Hepatogastroenterology. 2001 Sep-Oct;48(41):1266-70.
Title:	Proliferating cell nuclear antigen, p53, and c-erbB-2 expression in relation to clinicopathological variables and prognosis in cancer of the ampulla of Vater.
Author:	Ajiki, T\|Kamigaki, T\|Hasegawa, Y\|Fujino, Y\|Suzuki, Y\|Takeyama, Y\|Ku, Y\|Kuroda, Y
PMID:	11677943

10.
Journal:	Histopathology. 2002 Mar;40(3):269-78.
Title:	c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma.
Author:	Aishima, S-I\|Taguchi, K-I\|Sugimachi, K\|Shimada, M\|Sugimachi, K\|Tsuneyoshi, M
PMID:	11895493

11.
Journal:	J Hepatol. 2002 Jun;36(6):780-5.
Title:	Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry.
Author:	Ukita, Yoko\|Kato, Masako\|Terada, Tadashi
PMID:	12044528

12.
Journal:	Dig Liver Dis. 2003 May;35(5):332-8.
Title:	Investigation of ErbB1 and ErbB2 expression for therapeutic targeting in primary liver tumours.
Author:	Altimari, A\|Fiorentino, M\|Gabusi, E\|Gruppioni, E\|Corti, B\|D'Errico, A\|Grigioni, W F
PMID:	12846405

13.
Journal:	Hepatology. 2004 Jan;39(1):220-9.
Title:	MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type.
Author:	Shibahara, Hiroaki\|Tamada, Shugo\|Higashi, Michiyo\|Goto, Masamichi\|Batra, Surinder K\|Hollingsworth, Michael A\|Imai, Kohzoh\|Yonezawa, Suguru
PMID:	14752841

14.
Journal:	Oncol Rep. 2004 Apr;11(4):815-9.
Title:	Gallbladder cancers rarely overexpress HER-2/neu, demonstrated by Hercep test.
Author:	Matsuyama, Satoru\|Kitajima, Yoshihiko\|Sumi, Kenji\|Mori, Daisuke\|Satoh, Toshimi\|Miyazaki, Kohji
PMID:	15010878

15.
Journal:	Int J Oncol. 2004 May;24(5):1189-96.
Title:	Establishment and characterization of unique human gallbladder cancer cell lines.
Author:	Ghosh, Mila\|Koike, Naoto\|Yanagimoto, Go\|Tsunoda, Shin-Ichi\|Kaul, Sunil\|Hirano, Takashi\|Emura, Fabian\|Kashiwagi, Hironobu\|Kawamoto, Toru\|Ohkohchi, Nobuhiro\|Saijo, Kaoru\|Ohno, Tadao\|Miwa, Masanao\|Todoroki, Takeshi
PMID:	15067341

16.
Journal:	J Gastroenterol Hepatol. 2004 Jul;19(7):812-8.
Title:	Immunohistochemical study of microvessel density, CD44 (standard form), p53 protein and c-erbB2 in gallbladder carcinoma.
Author:	Kalekou, Harikleia\|Miliaras, Dimosthenis
PMID:	15209630

17.
Journal:	Int J Oncol. 2005 Feb;26(2):449-56.
Title:	Characterization and genetic analysis in the newly established human bile duct cancer cell lines.
Author:	Ghosh, Mila\|Koike, Naoto\|Tsunoda, Shin-Ichi\|Hirano, Takashi\|Kaul, Sunil\|Kashiwagi, Hironobu\|Kawamoto, Toru\|Ohkohchi, Nobuhiro\|Saijo, Kaoru\|Ohno, Tadao\|Miwa, Masanao\|Todoroki, Takeshi
PMID:	15645130

18.
Journal:	Korean J Gastroenterol. 2005 Jan;45(1):52-9.
Title:	[Expression of epidermal growth factor receptor, ErbB2 and matrix metalloproteinase-9 in hepatolithiasis and cholangiocarcinoma].
Author:	Kim, Hyo Jung\|Kim, Jae Seon\|Kang, Chang Don\|Lee, Sung Joon\|Kim, Jin Yong\|Yeon, Jong Eun\|Park, Jong-Jae\|Shim, Jae Jeong\|Byun, Kwan Soo\|Bak, Young-Tae\|Lee, Chang Hong
PMID:	15665568

19.
Journal:	Biochim Biophys Acta. 2005 Jul 25;1755(2):135-50.
Title:	Cyclooxygenase-2 and prostaglandin signaling in cholangiocarcinoma.
Author:	Wu, Tong
PMID:	15921858

20.
Journal:	Clin Cancer Res. 2005 Aug 1;11(15):5572-80.
Title:	Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma.
Author:	Kiguchi, Kaoru\|Ruffino, Lynnsie\|Kawamoto, Toru\|Ajiki, Tetsuo\|Digiovanni, John
PMID:	16061875

21.
Journal:	J Clin Pathol. 2005 Dec;58(12):1249-54.
Title:	FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma.
Author:	Settakorn, J\|Kaewpila, N\|Burns, G F\|Leong, A S-Y
PMID:	16311342

22.
Journal:	Gastroenterology. 2005 Dec;129(6):2047-57.
Title:	erbB-2/neu transformed rat cholangiocytes recapitulate key cellular and molecular features of human bile duct cancer.
Author:	Lai, Guan-Hua\|Zhang, Zichen\|Shen, Xue-Ning\|Ward, Deanna J\|Dewitt, Jennifer L\|Holt, Shawn E\|Rozich, Rebecca A\|Hixson, Douglas C\|Sirica, Alphonse E
PMID:	16344070

23.
Journal:	Cancer Res Treat. 2005 Jun;37(3):171-6.
Title:	Co-expression of cox-2, C-met and beta-catenin in cells forming invasive front of gallbladder cancer.
Author:	Moon, Woo Sung\|Park, Ho Sung\|Lee, Ho\|Pai, Rama\|Tarnawski, Andrzej S\|Kim, Kyung Ryoul\|Jang, Kyu Yun
PMID:	19956499

24.
Journal:	BMC Cancer. 2006 May 10;6:126.
Title:	Preliminary study of p53 and c-erbB-2 expression in gallbladder cancer in Indian patients manuscript id: 8962091628764582.
Author:	Chaube, Amita\|Tewari, Mallika\|Garbyal, R S\|Singh, Usha\|Shukla, Hari S
PMID:	16686942

25.
Journal:	Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4257-64.
Title:	MUC4 is a novel prognostic factor of extrahepatic bile duct carcinoma.
Author:	Tamada, Shugo\|Shibahara, Hiroaki\|Higashi, Michiyo\|Goto, Masamichi\|Batra, Surinder K\|Imai, Kohzoh\|Yonezawa, Suguru
PMID:	16857800

26.
Journal:	Ann Oncol. 2007 May;18(5):892-7. Epub 2007 Feb 23.
Title:	Gene amplification and protein overexpression of HER-2/neu in human extrahepatic cholangiocarcinoma as detected by chromogenic in situ hybridization and immunohistochemistry: its prognostic implication in node-positive patients.
Author:	Kim, H J\|Yoo, T W\|Park, D I\|Park, J H\|Cho, Y K\|Sohn, C I\|Jeon, W K\|Kim, B I\|Kim, M K\|Chae, S W\|Sohn, J H
PMID:	17322545

27.
Journal:	Cancer Res. 2007 Apr 15;67(8):3794-800.
Title:	Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.
Author:	Wu, Qi\|Kiguchi, Kaoru\|Kawamoto, Toru\|Ajiki, Tetsuo\|Traag, Jeanine\|Carbajal, Steve\|Ruffino, Lynnsie\|Thames, Howard\|Wistuba, Ignacio\|Thomas, Melanie\|Vasquez, Karen M\|DiGiovanni, John
PMID:	17440093

28.
Journal:	Anticancer Res. 2007 May-Jun;27(3B):1679-84.
Title:	Expression of p21(Wafl/Cip1), p57(Kip2) and HER2/neu in patients with gallbladder cancer.
Author:	Puhalla, H\|Wrba, F\|Kandioler, D\|Lehnert, M\|Huynh, A\|Gruenberger, T\|Tamandl, D\|Filipits, M
PMID:	17595796

29.
Journal:	Hepatobiliary Pancreat Dis Int. 2007 Aug;6(4):412-5.
Title:	Expression of c-erbB-2 proto-oncogene in extrahepatic cholangiocarcinoma and its clinical significance.
Author:	Zheng, Jun\|Zhu, Yao-Ming
PMID:	17690040

30.
Journal:	Korean J Gastroenterol. 2007 Dec;50(6):370-8.
Title:	[Expressions and clinical significances of c-met, c-erbB-2, COX-2, and IL-6 in the biliary tract cancers].
Author:	Joo, Hyun Ho\|Song, Eun Young\|Jin, Sang Hwa\|Oh, Sang Hoon\|Choi, Young Kil
PMID:	18159174

31.
Journal:	Gastrointest Cancer Res. 2007 Nov;1(6):221-7.
Title:	HER Receptor Family: Novel Candidate for Targeted Therapy for Gallbladder and Extrahepatic Bile Duct Cancer.
Author:	Kawamoto, Toru\|Krishnamurthy, Savitri\|Tarco, Emily\|Trivedi, Smita\|Wistuba, Ignacio I\|Li, Donghui\|Roa, Ivan\|Roa, Juan C\|Thomas, Melanie B
PMID:	19262900

32.
Journal:	Hepatology. 2008 Apr;47(4):1178-90.
Title:	A novel "patient-like" model of cholangiocarcinoma progression based on bile duct inoculation of tumorigenic rat cholangiocyte cell lines.
Author:	Sirica, Alphonse E\|Zhang, Zichen\|Lai, Guan-Hua\|Asano, Toru\|Shen, Xue-Ning\|Ward, Deanna J\|Mahatme, Arvind\|Dewitt, Jennifer L
PMID:	18081149

33.
Journal:	Br J Cancer. 2008 Jan 29;98(2):418-25. Epub 2007 Dec 18.
Title:	Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma.
Author:	Yoshikawa, D\|Ojima, H\|Iwasaki, M\|Hiraoka, N\|Kosuge, T\|Kasai, S\|Hirohashi, S\|Shibata, T
PMID:	18087285

34.
Journal:	Eur J Cancer. 2008 May;44(7):1048-56.
Title:	MUC4 interacts with ErbB2 in human gallbladder carcinoma: potential pathobiological implications.
Author:	Miyahara, Naoki\|Shoda, Junichi\|Ishige, Kazunori\|Kawamoto, Toru\|Ueda, Tetsuya\|Taki, Ryuuichi\|Ohkohchi, Nobuhiro\|Hyodo, Ichinosuke\|Thomas, Melanie B\|Krishnamurthy, Savitri\|Carraway, Kermit L\|Irimura, Tatsuro
PMID:	18397823

35.
Journal:	Int J Med Sci. 2008 Sep 22;5(5):285-91.
Title:	EGFR expression in gallbladder carcinoma in North America.
Author:	Kaufman, Matthew\|Mehrotra, Bhoomi\|Limaye, Sewanti\|White, Sherrie\|Fuchs, Alexander\|Lebowicz, Yehuda\|Nissel-Horowitz, Sandy\|Thomas, Adrienne
PMID:	18825277

36.
Journal:	Virchows Arch. 2008 Dec;453(6):579-88.
Title:	Immunophenotyping and oncogene amplifications in tumors of the papilla of Vater.
Author:	Baumhoer, Daniel\|Zlobec, Inti\|Tornillo, Luigi\|Dietmaier, Wolfgang\|Wuensch, Peter H\|Hartmann, Arndt\|Sessa, Fausto\|Ruemmele, Petra\|Terracciano, Luigi M
PMID:	18936968

37.
Journal:	World J Gastroenterol. 2008 Dec 14;14(46):7033-58.
Title:	Role of ErbB family receptor tyrosine kinases in intrahepatic cholangiocarcinoma.
Author:	Sirica, Alphonse-E
PMID:	19084911

38.
Journal:	Oncology. 2009;76(4):293-300.
Title:	A comprehensive analysis of immunohistochemical studies in intrahepatic cholangiocarcinoma using the survival tree model.
Author:	Iguchi, Tomohiro\|Yamashita, Natsumi\|Aishima, Shinichi\|Kuroda, Yousuke\|Terashi, Takahiro\|Sugimachi, Keishi\|Taguchi, Ken-ichi\|Taketomi, Akinobu\|Maehara, Yoshihiko\|Tsuneyoshi, Masazumi
PMID:	19262069

39.
Journal:	Anticancer Res. 2009 Jan;29(1):19-26.
Title:	Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma.
Author:	Ooi, Akishi\|Suzuki, Shioto\|Nakazawa, Kumiko\|Itakura, Jun\|Imoto, Issei\|Nakamura, Hiroyuki\|Dobashi, Yoh
PMID:	19331129

40.
Journal:	Hepatogastroenterology. 2009 May-Jun;56(91-92):606-9.
Title:	Expression of c-erbB-2 and cyclooxygenase-2 in intrahepatic cholangiocarcinoma.
Author:	Choi, Hye Jeong\|Kim, Hong Jin\|Choi, Joon Hyuk
PMID:	19621664

41.
Journal:	World J Gastroenterol. 2009 Sep 28;15(36):4511-7.
Title:	EGFR and HER2 expression in advanced biliary tract cancer.
Author:	Harder, Jan\|Waiz, Oliver\|Otto, Florian\|Geissler, Michael\|Olschewski, Manfred\|Weinhold, Brigitte\|Blum, Hubert E\|Schmitt-Graeff, Annette\|Opitz, Oliver G
PMID:	19777609

42.
Journal:	Hepatobiliary Pancreat Dis Int. 2009 Dec;8(6):620-6.
Title:	CA19-9 antigen levels can distinguish between benign and malignant pancreaticobiliary disease.
Author:	Morris-Stiff, Gareth\|Teli, Mary\|Jardine, Nicky\|Puntis, Malcolm Ca
PMID:	20007080

43.
Journal:	Cancer Sci. 2010 Jan;101(1):54-9.
Title:	Identification of transforming activity of free fatty acid receptor 2 by retroviral expression screening.
Author:	Hatanaka, Hisashi\|Tsukui, Mamiko\|Takada, Shuji\|Kurashina, Kentaro\|Choi, Young Lim\|Soda, Manabu\|Yamashita, Yoshihiro\|Haruta, Hidenori\|Hamada, Toru\|Ueno, Toshihide\|Tamada, Kiichi\|Hosoya, Yoshinori\|Sata, Naohiro\|Yasuda, Yoshikazu\|Nagai, Hideo\|Sugano, Kentaro
PMID:	19780758

44.
Journal:	Hum Pathol. 2010 Apr;41(4):485-92.
Title:	Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder.
Author:	Shafizadeh, Nafis\|Grenert, James P\|Sahai, Vaibhav\|Kakar, Sanjay
PMID:	20040392

45.
Journal:	Hepatology. 2010 Sep;52(3):975-86.
Title:	Preclinical assessment of simultaneous targeting of epidermal growth factor receptor (ErbB1) and ErbB2 as a strategy for cholangiocarcinoma therapy.
Author:	Zhang, Zichen\|Oyesanya, Regina A\|Campbell, Deanna J W\|Almenara, Jorge A\|Dewitt, Jennifer L\|Sirica, Alphonse E
PMID:	20607690

46.
Journal:	Exp Mol Pathol. 2010 Dec;89(3):248-59.
Title:	Accumulation of neoplastic traits prior to spontaneous in vitro transformation of rat cholangiocytes determines susceptibility to activated ErbB-2/Neu.
Author:	Rozich, Rebecca A\|Mills, David R\|Brilliant, Kate E\|Callanan, Helen M\|Yang, DongQin\|Tantravahi, Umadevi\|Hixson, Douglas C
PMID:	20655306

47.
Journal:	World J Gastroenterol. 2010 Aug 28;16(32):4047-54.
Title:	High expression of ErbB2 contributes to cholangiocarcinoma cell invasion and proliferation through AKT/p70S6K.
Author:	Treekitkarnmongkol, Warapen\|Suthiphongchai, Tuangporn
PMID:	20731018

48.
Journal:	Exp Mol Pathol. 2010 Dec;89(3):227-35.
Title:	Differential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas.
Author:	Dumur, Catherine I\|Campbell, Deanna J W\|DeWitt, Jennifer L\|Oyesanya, Regina A\|Sirica, Alphonse E
PMID:	20816680

49.
Journal:	HPB (Oxford). 2011 May;13(5):309-19.
Title:	Array comparative genomic hybridization identifies novel potential therapeutic targets in cholangiocarcinoma.
Author:	McKay, Siobhan C\|Unger, Kristian\|Pericleous, Stephanos\|Stamp, Gordon\|Thomas, Gerry\|Hutchins, Robert R\|Spalding, Duncan R C
PMID:	21492330

50.
Journal:	Gastroenterology. 2012 Apr;142(4):1021-1031.e15.
Title:	Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors.
Author:	Andersen, Jesper B\|Spee, Bart\|Blechacz, Boris R\|Avital, Itzhak\|Komuta, Mina\|Barbour, Andrew\|Conner, Elizabeth A\|Gillen, Matthew C\|Roskams, Tania\|Roberts, Lewis R\|Factor, Valentina M\|Thorgeirsson, Snorri S
PMID:	22178589

51.
Journal:	J Hepatol. 2012 Jul;57(1):84-91.
Title:	The therapeutic effect of histone deacetylase inhibitor PCI-24781 on gallbladder carcinoma in BK5.erbB2 mice.
Author:	Kitamura, Takuya\|Connolly, Kevin\|Ruffino, Lynnsie\|Ajiki, Tetsuo\|Lueckgen, Aline\|DiGiovanni, John\|Kiguchi, Kaoru
PMID:	22326466

52.
Journal:	World J Gastroenterol. 2012 Mar 21;18(11):1208-15.
Title:	Expression of HER2 and bradykinin B(1) receptors in precursor lesions of gallbladder carcinoma.
Author:	Toledo, Cesar\|Matus, Carola E\|Barraza, Ximena\|Arroyo, Pamela\|Ehrenfeld, Pamela\|Figueroa, Carlos D\|Bhoola, Kanti D\|Del Pozo, Maeva\|Poblete, Maria T
PMID:	22468084

53.
Journal:	Indian J Pathol Microbiol. 2012 Jan-Mar;55(1):75-9.
Title:	Role of C-erbB2 expression in gallbladder cancer.
Author:	Kumari, Niraj\|Kapoor, V K\|Krishnani, Narendra\|Kumar, Kamlesh\|Baitha, Dinesh Kumar
PMID:	22499306

54.
Journal:	Virchows Arch. 2012 Nov;461(5):521-30.
Title:	HER3 overexpression is a prognostic indicator of extrahepatic cholangiocarcinoma.
Author:	Lee, Hee Jin\|Chung, Joon-Yong\|Hewitt, Stephen M\|Yu, Eunsil\|Hong, Seung-Mo
PMID:	23052372

55.
Journal:	Oncotarget. 2013 Jan;4(1):156-65.
Title:	Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials.
Author:	Subbiah, Ishwaria M\|Subbiah, Vivek\|Tsimberidou, Apostolia M\|Naing, Aung\|Kaseb, Ahmed O\|Javle, Milind\|Fu, Siqing\|Hong, David S\|Piha-Paul, Sarina\|Wheler, Jennifer J\|Hess, Kenneth R\|Janku, Filip\|Falchook, Gerald S\|Wolff, Robert A\|Kurzrock, Razelle
PMID:	23391555

56.
Journal:	Korean J Intern Med. 2013 Sep;28(5):573-8.
Title:	Expression of procaspase 3 and activated caspase 3 and its relevance in hormone-responsive gallbladder carcinoma chemotherapy.
Author:	Maurya, Sanjeev Kumar\|Tewari, Mallika\|Sharma, Bechan\|Shukla, Hari Shanker
PMID:	24009453

57.
Journal:	Mod Pathol. 2014 Jan;27(1):73-86.
Title:	Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.
Author:	Schlitter, Anna Melissa\|Born, Diana\|Bettstetter, Marcus\|Specht, Katja\|Kim-Fuchs, Corina\|Riener, Marc-Oliver\|Jeliazkova, Petia\|Sipos, Bence\|Siveke, Jens T\|Terris, Benoit\|Zen, Yoh\|Schuster, Tibor\|Hofler, Heinz\|Perren, Aurel\|Kloppel, Gunter\|Esposito, Irene
PMID:	23828315

58.
Journal:	Mol Cancer Res. 2014 Jan;12(1):91-100.
Title:	Cocarcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development.
Author:	Lozano, Elisa\|Sanchez-Vicente, Laura\|Monte, Maria J\|Herraez, Elisa\|Briz, Oscar\|Banales, Jesus M\|Marin, Jose J G\|Macias, Rocio I R
PMID:	24255171

59.
Journal:	J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):371-9.
Title:	Molecular aspects of cholangiocarcinoma.
Author:	Kiguchi, Kaoru
PMID:	24420749

60.
Journal:	J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):380-7.
Title:	Genomic and transcriptional alterations of cholangiocarcinoma.
Author:	Ito, Takeshi\|Sakurai-Yageta, Mika\|Goto, Akiteru\|Pairojkul, Chawalit\|Yongvanit, Puangrat\|Murakami, Yoshinori
PMID:	24532422

61.
Journal:	J Gastroenterol Hepatol. 2014 Aug;29(8):1582-94.
Title:	Differences in immunohistochemical biomarkers between intra- and extrahepatic cholangiocarcinoma: a systematic review and meta-analysis.
Author:	Wiggers, Jimme K\|Ruys, Anthony T\|Groot Koerkamp, Bas\|Beuers, Ulrich\|ten Kate, Fiebo J\|van Gulik, Thomas M
PMID:	24787096

62.
Journal:	Gastrointest Cancer Res. 2014 Mar;7(2):42-8.
Title:	Overexpression of the HER2/neu Gene: A New Therapeutic Possibility for Patients With Advanced Gallbladder Cancer.
Author:	Roa, Ivan\|de Toro, Gonzalo\|Schalper, Kurt\|de Aretxabala, Xabier\|Churi, Chaitanya\|Javle, Milind
PMID:	24799970

63.
Journal:	Hum Pathol. 2014 Aug;45(8):1630-8.
Title:	Fibroblast growth factor receptor 2 translocations in intrahepatic cholangiocarcinoma.
Author:	Graham, Rondell P\|Barr Fritcher, Emily G\|Pestova, Ekaterina\|Schulz, John\|Sitailo, Leonid A\|Vasmatzis, George\|Murphy, Stephen J\|McWilliams, Robert R\|Hart, Steven N\|Halling, Kevin C\|Roberts, Lewis R\|Gores, Gregory J\|Couch, Fergus J\|Zhang, Lizhi\|Borad, Mites
PMID:	24837095

64.
Journal:	Am Soc Clin Oncol Educ Book. 2014:e165-70.
Title:	A review of recent data in the treatment of gallbladder cancer: what we know, what we do, and what should be done.
Author:	Muller, Bettina G\|De Aretxabala, Xabier\|Gonzalez Domingo, Manuel
PMID:	24857099

65.
Journal:	Oncol Rep. 2014 Aug;32(2):700-8.
Title:	Characterization of EGFR family gene aberrations in cholangiocarcinoma.
Author:	Yang, Xiaoqing\|Wang, Weishan\|Wang, Chunni\|Wang, Lin\|Yang, Muyi\|Qi, Mei\|Su, Hong\|Sun, Xiubin\|Liu, Zhiyan\|Zhang, Juan\|Qin, Xiaomin\|Han, Bo
PMID:	24927194

66.
Journal:	Nat Genet. 2014 Aug;46(8):872-6.
Title:	Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway.
Author:	Li, Maolan\|Zhang, Zhou\|Li, Xiaoguang\|Ye, Junyi\|Wu, Xiangsong\|Tan, Zhujun\|Liu, Chang\|Shen, Baiyong\|Wang, Xu-An\|Wu, Wenguang\|Zhou, Daizhan\|Zhang, Di\|Wang, Ting\|Liu, Bingya\|Qu, Kai\|Ding, Qichen\|Weng, Hao\|Ding, Qian\|Mu, Jiasheng\|Shu, Yijun\|Bao, Runfa\|Cao, Yan
PMID:	24997986

67.
Journal:	Oncol Rep. 2014 Nov;32(5):1796-802.
Title:	Interaction of Muc4 and ErbB2 in a transgenic mouse model of gallbladder carcinoma: potential pathobiological implications.
Author:	Miyahara, Naoki\|Shoda, Junichi\|Kawamoto, Toru\|Ishida, Hiroyasu\|Ueda, Tetsuya\|Akimoto, Yoshihiro\|Kawakami, Hayato\|Irimura, Tatsuro
PMID:	25174601

68.
Journal:	Biochem Biophys Res Commun. 2014 Sep 26;452(3):614-21.
Title:	SOX4 is associated with poor prognosis in cholangiocarcinoma.
Author:	Wang, Weishan\|Zhang, Jing\|Zhan, Xuemei\|Lin, Tao\|Yang, Muyi\|Hu, Jing\|Han, Bo\|Hu, Sanyuan
PMID:	25181339

69.
Journal:	PLoS One. 2014 Dec 23;9(12):e115383.
Title:	Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications.
Author:	Churi, Chaitanya R\|Shroff, Rachna\|Wang, Ying\|Rashid, Asif\|Kang, HyunSeon C\|Weatherly, Jacqueline\|Zuo, Mingxin\|Zinner, Ralph\|Hong, David\|Meric-Bernstam, Funda\|Janku, Filip\|Crane, Christopher H\|Mishra, Lopa\|Vauthey, Jean-Nicholas\|Wolff, Robert A\|Mills, Gord
PMID:	25536104

70.
Journal:	Mol Carcinog. 2015 Jun;54(6):459-72.
Title:	Bile acid accelerates erbB2-induced pro-tumorigenic activities in biliary tract cancer.
Author:	Kitamura, Takuya\|Srivastava, Jaya\|DiGiovanni, John\|Kiguchi, Kaoru
PMID:	24839254

71.
Journal:	Pathol Oncol Res. 2015 Jul;21(3):831-8.
Title:	Prognostic value of increased HER2 expression in cancers of pancreas and biliary tree.
Author:	Ata, Alper\|Polat, Ayse\|Serinsoz, Ebru\|Sungur, Mehmet Ali\|Arican, Ali
PMID:	25416598

72.
Journal:	Virchows Arch. 2015 Apr;466(4):393-402.
Title:	Microsatellite instability in gallbladder carcinoma.
Author:	Moy, Andrea P\|Shahid, Mohammad\|Ferrone, Cristina R\|Borger, Darrell R\|Zhu, Andrew X\|Ting, David\|Deshpande, Vikram
PMID:	25680569

73.
Journal:	Cancer Metastasis Rev. 2015 Mar;34(1):157-64.
Title:	HER2 expression status in diverse cancers: review of results from 37,992 patients.
Author:	Yan, Min\|Schwaederle, Maria\|Arguello, David\|Millis, Sherri Z\|Gatalica, Zoran\|Kurzrock, Razelle
PMID:	25712293

74.
Journal:	J Hepatol. 2015 Aug;63(2):399-407.
Title:	Breast tumor kinase/protein tyrosine kinase 6 (Brk/PTK6) activity in normal and neoplastic biliary epithelia.
Author:	Mizuguchi, Yoshiaki\|Specht, Susan\|Isse, Kumiko\|Sasatomi, Eizaburo\|Lunz, John G 3rd\|Takizawa, Toshihiro\|Demetris, Anthony J
PMID:	25770659

75.
Journal:	Mod Pathol. 2015 Aug;28(8):1123-9.
Title:	Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2).
Author:	Hechtman, Jaclyn F\|Liu, Weiguo\|Sadowska, Justyna\|Zhen, Lisa\|Borsu, Laetitia\|Arcila, Maria E\|Won, Helen H\|Shah, Ronak H\|Berger, Michael F\|Vakiani, Efsevia\|Shia, Jinru\|Klimstra, David S
PMID:	25975284

76.
Journal:	J Hematol Oncol. 2015 May 29;8:58.
Title:	HER2/neu-directed therapy for biliary tract cancer.
Author:	Javle, Milind\|Churi, Chaitanya\|Kang, HyunSeon C\|Shroff, Rachna\|Janku, Filip\|Surapaneni, Rakesh\|Zuo, Mingxin\|Barrera, Christian\|Alshamsi, Humaid\|Krishnan, Sunil\|Mishra, Lopa\|Wolff, Robert A\|Kaseb, Ahmed O\|Thomas, Melanie B\|Siegel, Abby B
PMID:	26022204

77.
Journal:	Mod Pathol. 2015 Sep;28(9):1249-64.
Title:	Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases.
Author:	Schlitter, Anna Melissa\|Jang, Kee-Taek\|Kloppel, Gunter\|Saka, Burcu\|Hong, Seung-Mo\|Choi, Hyejeong\|Offerhaus, George Johan\|Hruban, Ralph H\|Zen, Yoh\|Konukiewitz, Bjorn\|Regel, Ivonne\|Allgauer, Michael\|Balci, Serdar\|Basturk, Olca\|Reid, Michelle D\|Esposito, Ire
PMID:	26111977

78.
Journal:	PLoS One. 2015 Nov 16;10(11):e0142124.
Title:	Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures.
Author:	Fraveto, Alice\|Cardinale, Vincenzo\|Bragazzi, Maria Consiglia\|Giuliante, Felice\|De Rose, Agostino Maria\|Grazi, Gian Luca\|Napoletano, Chiara\|Semeraro, Rossella\|Lustri, Anna Maria\|Costantini, Daniele\|Nevi, Lorenzo\|Di Matteo, Sabina\|Renzi, Anastasia\|Carpino,
PMID:	26571380

79.
Journal:	Tumour Biol. 2016 Mar;37(3):4041-52.
Title:	Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient.
Author:	Cavalloni, Giuliana\|Peraldo-Neia, Caterina\|Varamo, Chiara\|Casorzo, Laura\|Dell'Aglio, Carmine\|Bernabei, Paola\|Chiorino, Giovanna\|Aglietta, Massimo\|Leone, Francesco
PMID:	26486326

80.
Journal:	J Clin Pathol. 2016 May;69(5):403-8.
Title:	Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets.
Author:	Lee, Hwajeong\|Wang, Kai\|Johnson, Adrienne\|Jones, David M\|Ali, Siraj M\|Elvin, Julia A\|Yelensky, Roman\|Lipson, Doron\|Miller, Vincent A\|Stephens, Philip J\|Javle, Milind\|Ross, Jeffrey S
PMID:	26500333

81.
Journal:	Expert Opin Biol Ther. 2016;16(2):243-53.
Title:	Pertuzumab in gastrointestinal cancer.
Author:	Oh, Do-Youn\|Bang, Yung-Jue
PMID:	26619359

82.
Journal:	Virchows Arch. 2016 Apr;468(4):431-9.
Title:	A significant subgroup of resectable gallbladder cancer patients has an HER2 positive status.
Author:	Yoshida, Hiroshi\|Shimada, Kazuaki\|Kosuge, Tomoo\|Hiraoka, Nobuyoshi
PMID:	26758058

83.
Journal:	Cancer Metastasis Rev. 2016 Jun;35(2):263-75.
Title:	Genomics of gallbladder cancer: the case for biomarker-driven clinical trial design.
Author:	Sicklick, Jason K\|Fanta, Paul T\|Shimabukuro, Kelly\|Kurzrock, Razelle
PMID:	26857926

84.
Journal:	Gulf J Oncolog. 2016 Jan;1(20):12-9.
Title:	EGFR and HER-2/neu Expression in Gallbladder Carcinoma: An Institutional Experience.
Author:	Hadi, R\|Pant, M C\|Husain, N\|Singhal, A\|Khurana, R\|Agarwal, G R\|Masood, S\|Awashthi, N P
PMID:	27050174

85.
Journal:	Z Gastroenterol. 2016 May;54(5):426-30.
Title:	[Durable remission under dual HER2 blockade with Trastuzumab and Pertuzumab in a patient with metastatic gallbladder cancer].
Author:	Czink, E\|Heining, C\|Weber, T F\|Lasitschka, F\|Schemmer, P\|Schirmacher, P\|Weiss, K H\|Glimm, H\|Brors, B\|Weichert, W\|Jager, D\|Frohling, S\|Springfeld, C
PMID:	27171333

86.
Journal:	Transl Oncol. 2016 Jun;9(3):173-8.
Title:	Genomic Alterations in Biliary Tract Cancer Using Targeted Sequencing.
Author:	Yoo, Kwai Han\|Kim, Nayoung K D\|Kwon, Woo Il\|Lee, Chung\|Kim, Sun Young\|Jang, Jiryeon\|Ahn, Jungmi\|Kang, Mihyun\|Jang, Hyojin\|Kim, Seung Tae\|Ahn, Soomin\|Jang, Kee-Taek\|Park, Young Suk\|Park, Woong-Yang\|Lee, Jeeyun\|Heo, Jin Seok\|Park, Joon Oh
PMID:	27267833

87.
Journal:	Oncotarget. 2016 Sep 6;7(36):58007-58021.
Title:	Therapeutic implication of HER2 in advanced biliary tract cancer.
Author:	Nam, Ah-Rong\|Kim, Ji-Won\|Cha, Yongjun\|Ha, Hyerim\|Park, Ji Eun\|Bang, Ju-Hee\|Jin, Mei Hua\|Lee, Kyung-Hun\|Kim, Tae-Yong\|Han, Sae-Won\|Im, Seock-Ah\|Kim, Tae-You\|Oh, Do-Youn\|Bang, Yung-Jue
PMID:	27517322

88.
Journal:	Cancer. 2016 Dec 15;122(24):3838-3847.
Title:	Biliary cancer: Utility of next-generation sequencing for clinical management.
Author:	Javle, Milind\|Bekaii-Saab, Tanios\|Jain, Apurva\|Wang, Ying\|Kelley, Robin Katie\|Wang, Kai\|Kang, Hyunseon C\|Catenacci, Daniel\|Ali, Siraj\|Krishnan, Sunil\|Ahn, Daniel\|Bocobo, Andrea Grace\|Zuo, Mingxin\|Kaseb, Ahmed\|Miller, Vincent\|Stephens, Philip J\|Meric-Berns
PMID:	27622582

89.
Journal:	Asian Pac J Cancer Prev. 2016;17(8):3903-9.
Title:	Expression of Human Epidermal Growth Factor Receptor (Her 2/neu) and Proliferative Marker Ki-67: Association with Clinicopathological Parameters in Gallbladder Carcinoma.
Author:	Pujani, Mukta\|Makker, Isha\|Makker, Annu\|Jetley, Sujata\|Goel, Madhu Mati\|Jetley, Sujata
PMID:	27644637

90.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):797-803.
Title:	Molecular profiling of biliary tract cancer: a target rich disease.
Author:	Jain, Apurva\|Javle, Milind
PMID:	27747093

91.
Journal:	Cancer Metastasis Rev. 2017 Mar;36(1):141-157.
Title:	HER2/HER3 pathway in biliary tract malignancies; systematic review and meta-analysis: a potential therapeutic target?
Author:	Galdy, Salvatore\|Lamarca, Angela\|McNamara, Mairead G\|Hubner, Richard A\|Cella, Chiara A\|Fazio, Nicola\|Valle, Juan W
PMID:	27981460

92.
Journal:	Mol Cancer Ther. 2017 Jun;16(6):1145-1154.
Title:	Resistance Mechanism against Trastuzumab in HER2-Positive Cancer Cells and Its Negation by Src Inhibition.
Author:	Jin, Mei Hua\|Nam, Ah-Rong\|Park, Ji Eun\|Bang, Ju-Hee\|Bang, Yung-Jue\|Oh, Do-Youn
PMID:	28223426

93.
Journal:	Pathol Res Pract. 2017 May;213(5):476-482.
Title:	The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer.
Author:	Buchegger, Kurt\|Silva, Ramon\|Lopez, Jaime\|Ili, Carmen\|Araya, Juan Carlos\|Leal, Pamela\|Brebi, Priscilla\|Riquelme, Ismael\|Roa, Juan Carlos
PMID:	28285962

94.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2017 Apr 8;46(4):245-248.
Title:	[Clinical significance of HER2 positivity in gallbladder adenocarcinoma].
Author:	Yao, J G\|Wang, C H\|Liu, Y
PMID:	28376590

95.
Journal:	Mol Carcinog. 2017 Sep;56(9):2146-2157.
Title:	High mobility group A1 enhances tumorigenicity of human cholangiocarcinoma and confers resistance to therapy.
Author:	Quintavalle, Cristina\|Burmeister, Katharina\|Piscuoglio, Salvatore\|Quagliata, Luca\|Karamitopoulou, Eva\|Sepe, Romina\|Fusco, Alfredo\|Terracciano, Luigi M\|Andersen, Jesper B\|Pallante, Pierlorenzo\|Matter, Matthias S
PMID:	28467612

96.
Journal:	Therap Adv Gastroenterol. 2017 Jun;10(6):507-520.
Title:	The potential role of comprehensive genomic profiling to guide targeted therapy for patients with biliary cancer.
Author:	Lee, Hwajeong\|Ross, Jeffrey S
PMID:	28567120

97.
Journal:	Hepatology. 2017 Jul 3.
Title:	Role of ErbB/HER family of receptor tyrosine kinases in cholangiocyte biology.
Author:	Pellat, Anna\|Vaquero, Javier\|Fouassier, Laura
PMID:	28671339

98.
Journal:	J Gastrointest Oncol. 2017 Jun;8(3):430-440.
Title:	Current biologics for treatment of biliary tract cancers.
Author:	Zhao, Diana Y\|Lim, Kian-Huat
PMID:	28736630

99.
Journal:	Pathology. 2017 Oct;49(6):582-588.
Title:	Gene copy number variation and protein overexpression of EGFR and HER2 in distal extrahepatic cholangiocarcinoma.
Author:	Jung, Min Jung\|Woo, Chang Gok\|Lee, Saetbyeol\|Chin, Susie\|Kim, Hee Kyung\|Kwak, Jeong Ja\|Koh, Eun Suk\|Lee, Bora\|Jang, Kee-Taek\|Moon, Ahrim
PMID:	28843919

100.
Journal:	Am J Cancer Res. 2018 Jan 1;8(1):2-15. eCollection 2018.
Title:	Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers.
Author:	Papadopoulou, Kyriaki\|Murray, Samuel\|Manousou, Kyriaki\|Tikas, Ioannis\|Dervenis, Christos\|Sgouros, Joseph\|Rontogianni, Dimitra\|Lakis, Sotirios\|Bobos, Mattheos\|Poulios, Christos\|Pervana, Stavroula\|Lazaridis, Georgios\|Fountzilas, George\|Kotoula, Vassiliki
PMID:	29416916

101.
Journal:	Future Oncol. 2018 Mar;14(6):553-566.
Title:	Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma.
Author:	DeLeon, Thomas T\|Ahn, Daniel H\|Bogenberger, James M\|Anastasiadis, Panos Z\|Arora, Mansi\|Ramanathan, Ramesh K\|Aqel, Bashar A\|Vasmatzis, George\|Truty, Mark J\|Oklu, Rahmi\|Bekaii-Saab, Tanios S\|Borad, Mitesh J
PMID:	29460642

102.
Journal:	Pathol Res Pract. 2018 Jun;214(6):835-839.
Title:	MiR-21 up-regulation in ampullary adenocarcinoma and its pre-invasive lesions.
Author:	Saraggi, Deborah\|Galuppini, Francesca\|Fanelli, Giuseppe N\|Remo, Andrea\|Urso, Emanuele D L\|Bao, Ricardo Q\|Bacchin, Deborah\|Guzzardo, Vincenza\|Luchini, Claudio\|Braconi, Chiara\|Farinati, Fabio\|Rugge, Massimo\|Fassan, Matteo
PMID:	29731265

103.
Journal:	Clin Cancer Res. 2018 Sep 1;24(17):4154-4161.
Title:	Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention.
Author:	Lowery, Maeve A\|Ptashkin, Ryan\|Jordan, Emmet\|Berger, Michael F\|Zehir, Ahmet\|Capanu, Marinela\|Kemeny, Nancy E\|O'Reilly, Eileen M\|El-Dika, Imane\|Jarnagin, William R\|Harding, James J\|D'Angelica, Michael I\|Cercek, Andrea\|Hechtman, Jaclyn F\|Solit, David B\|Schu
PMID:	29848569

104.
Journal:	Jpn J Clin Oncol. 2018 Aug 1;48(8):703-711.
Title:	New developments in systemic therapy for advanced biliary tract cancer.
Author:	Morizane, Chigusa\|Ueno, Makoto\|Ikeda, Masafumi\|Okusaka, Takuji\|Ishii, Hiroshi\|Furuse, Junji
PMID:	29893894

105.
Journal:	BMC Cancer. 2018 Jun 18;18(1):665.
Title:	Gallbladder cancer: review of a rare orphan gastrointestinal cancer with a focus on populations of New Mexico.
Author:	Nemunaitis, Jacklyn M\|Brown-Glabeman, Ursa\|Soares, Heloisa\|Belmonte, Jessica\|Liem, Ben\|Nir, Itzhak\|Phuoc, Victor\|Gullapalli, Rama R
PMID:	29914418

106.
Journal:	Gut. 2018 Jun 28. pii: gutjnl-2018-316039.
Title:	Genomic ERBB2/ERBB3 mutations promote PD-L1-mediated immune escape in gallbladder cancer: a whole-exome sequencing analysis.
Author:	Li, Maolan\|Liu, Fatao\|Zhang, Fei\|Zhou, Weiping\|Jiang, Xiaoqing\|Yang, Yuan\|Qu, Kai\|Wang, Yueqi\|Ma, Qiang\|Wang, Ting\|Bai, Lu\|Wang, Zheng\|Song, Xiaoling\|Zhu, Yidi\|Yuan, Ruiyan\|Gao, Yuan\|Liu, Yongchen\|Jin, Yunpeng\|Li, Huaifeng\|Xiang, Shanshan\|Ye, Yuanyuan\|Zha
PMID:	29954840

107.
Journal:	J Gastrointest Cancer. 2018 Aug 29. pii: 10.1007/s12029-018-0162-8.
Title:	Significance of HER2 and Ki-67 in Preneoplastic Lesions and Carcinoma of Gallbladder.
Author:	Halder, Sutapa\|Kundu, Sayan\|Chakraborty, Jayati\|Chakrabarti, Sudipta
PMID:	30155833

108.
Journal:	Int J Cancer. 2018 Oct 10.
Title:	ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in Early Stage Gallbladder Cancer.
Author:	Iyer, Prajish\|Shrikhande, Shailesh V\|Ranjan, Malika\|Joshi, Asim\|Gardi, Nilesh\|Prasad, Ratnam\|Dharavath, Bhasker\|Thorat, Rahul\|Salunkhe, Sameer\|Sahoo, Bikram\|Chandrani, Pratik\|Kore, Hitesh\|Mohanty, Bhabani\|Chaudhari, Vikram\|Choughule, Anuradha\|Kawle, Dhana
PMID:	30304546

109.
Journal:	PLoS One. 2018 Oct 18;13(10):e0206007.
Title:	The HER3 pathway as a potential target for inhibition in patients with biliary tract cancers.
Author:	Lamarca, Angela\|Galdy, Salvatore\|Barriuso, Jorge\|Moghadam, Sharzad\|Beckett, Elizabeth\|Rogan, Jane\|Backen, Alison\|Billington, Catherine\|McNamara, Mairead G\|Hubner, Richard A\|Cramer, Angela\|Valle, Juan W
PMID:	30335866