Primary Site >> Colorectal Cancer

Gene >> EPHB4

Journal: Oncogene. 1996 Aug 15;13(4):813-22.
Title: Characterization of a ligand for receptor protein-tyrosine kinase HTK expressed in immature hematopoietic cells.
Author: Sakano, S|Serizawa, R|Inada, T|Iwama, A|Itoh, A|Kato, C|Shimizu, Y|Shinkai, F|Shimizu, R|Kondo, S|Ohno, M|Suda, T
PMID: 8761303
Journal: BMC Mol Biol. 2001;2:15. Epub 2001 Dec 21.
Title: Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer.
Author: Stephenson, S A|Slomka, S|Douglas, E L|Hewett, P J|Hardingham, J E
PMID: 11801186
Journal: Cancer. 2002 Feb 15;94(4):934-9.
Title: Coexpression of ephrin-Bs and their receptors in colon carcinoma.
Author: Liu, Wenbiao|Ahmad, Syed A|Jung, Young D|Reinmuth, Niels|Fan, Fan|Bucana, Corazon D|Ellis, Lee M
PMID: 11920461
Journal: Neoplasia. 2004 May-Jun;6(3):248-57.
Title: Inhibition of tumor growth and angiogenesis by soluble EphB4.
Author: Martiny-Baron, Georg|Korff, Thomas|Schaffner, Florence|Esser, Norbert|Eggstein, Stefan|Marme, Dieter|Augustin, Hellmut G
PMID: 15153337
Journal: Cancer Res. 2006 Sep 15;66(18):8943-8.
Title: EPHB4 and survival of colorectal cancer patients.
Author: Davalos, Veronica|Dopeso, Higinio|Castano, Julio|Wilson, Andrew J|Vilardell, Felip|Romero-Gimenez, Jordi|Espin, Eloy|Armengol, Manel|Capella, Gabriel|Mariadason, John M|Aaltonen, Lauri A|Schwartz, Simo Jr|Arango, Diego
PMID: 16982731
Journal: Epigenetics. 2007 Oct-Dec;2(4):237-43. Epub 2007 Dec 9.
Title: The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers.
Author: Wu, Qinghua|Lind, Guro E|Aasheim, Hans-Christian|Micci, Francesca|Silins, Ilvars|Trope, Claes G|Nesland, Jahn M|Lothe, Ragnhild A|Suo, Zhenhe
PMID: 18281782
Journal: Cancer Res. 2009 May 1;69(9):3736-45.
Title: Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.
Author: Kumar, S Ram|Scehnet, Jeffrey S|Ley, Eric J|Singh, Jasbir|Krasnoperov, Valery|Liu, Ren|Manchanda, Parmeet K|Ladner, Robert D|Hawes, Debra|Weaver, Fred A|Beart, Robert W|Singh, Gagandeep|Nguyen, Cu|Kahn, Michael|Gill, Parkash S
PMID: 19366806
Journal: Carcinogenesis. 2009 Sep;30(9):1475-86.
Title: Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells.
Author: Chiu, Sou-Tyau|Chang, King-Jen|Ting, Chen-Hung|Shen, Hsi-Che|Li, Hung|Hsieh, Fon-Jou
PMID: 19483190
Journal: Cancer Res. 2009 Sep 15;69(18):7430-8.
Title: The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.
Author: Dopeso, Higinio|Mateo-Lozano, Silvia|Mazzolini, Rocco|Rodrigues, Paulo|Lagares-Tena, Laura|Ceron, Julian|Romero, Jordi|Esteves, Marielle|Landolfi, Stefania|Hernandez-Losa, Javier|Castano, Julio|Wilson, Andrew J|Ramon y Cajal, Santiago|Mariadason, John M|S
PMID: 19738063
Journal: BMC Genomics. 2010 Dec 20;11:717.
Title: Combining modularity, conservation, and interactions of proteins significantly increases precision and coverage of protein function prediction.
Author: Jaeger, Samira|Sers, Christine T|Leser, Ulf
PMID: 21171995
Journal: Epigenetics. 2011 May;6(5):610-22. Epub 2011 May 1.
Title: Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer.
Author: Ronsch, Kerstin|Jager, Marcel|Schopflin, Anja|Danciu, Mihai|Lassmann, Silke|Hecht, Andreas
PMID: 21393996
Journal: Eur J Cancer. 2012 Mar;48(5):753-62.
Title: Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis.
Author: Herath, Nirmitha I|Spanevello, Mark D|Doecke, James D|Smith, Fiona M|Pouponnot, Celio|Boyd, Andrew W
PMID: 21852108
Journal: Mol Pharm. 2013 Jan 7;10(1):329-36.
Title: Targeting the EphB4 receptor for cancer diagnosis and therapy monitoring.
Author: Li, Dan|Liu, Shuanglong|Liu, Ren|Park, Ryan|Hughes, Lindsey|Krasnoperov, Valery|Gill, Parkash S|Li, Zibo|Shan, Hong|Conti, Peter S
PMID: 23211050
Journal: J Nucl Med. 2013 Jul;54(7):1094-100.
Title: PET imaging of colorectal and breast cancer by targeting EphB4 receptor with 64Cu-labeled hAb47 and hAb131 antibodies.
Author: Liu, Shuanglong|Li, Dan|Park, Ryan|Liu, Ren|Xia, Zanxian|Guo, Jiacong|Krasnoperov, Valery|Gill, Parkash S|Li, Zibo|Shan, Hong|Conti, Peter S
PMID: 23667241
Journal: Med Oncol. 2013;30(2):572.
Title: Gene expression profiling identifies EPHB4 as a potential predictive biomarker in colorectal cancer patients treated with bevacizumab.
Author: Guijarro-Munoz, Irene|Sanchez, Antonio|Martinez-Martinez, Esther|Garcia, Jose M|Salas, Clara|Provencio, Mariano|Alvarez-Vallina, Luis|Sanz, Laura
PMID: 23579861
Journal: Biochim Biophys Acta. 2013 Nov;1834(11):2372-9.
Title: Detection of cadherin-17 in human colon cancer LIM1215 cell secretome and tumour xenograft-derived interstitial fluid and plasma.
Author: Bernhard, Oliver K|Greening, David W|Barnes, Thomas W|Ji, Hong|Simpson, Richard J
PMID: 23557862
Journal: Int J Cancer. 2015 Apr 15;136(8):1781-91.
Title: EPHB4 tyrosine-kinase receptor expression and biological significance in soft tissue sarcoma.
Author: Becerikli, M|Merwart, B|Lam, M C|Suppelna, P|Rittig, A|Mirmohammedsadegh, A|Stricker, I|Theiss, C|Singer, B B|Jacobsen, F|Steinstraesser, L
PMID: 25274141
Journal: Int J Cancer. 2016 Mar 1;138(5):1220-31.
Title: Differential protein expression and oncogenic gene network link tyrosine kinase ephrin B4 receptor to aggressive gastric and gastroesophageal junction cancers.
Author: Liersch-Lohn, Britta|Slavova, Nadia|Buhr, Heinz J|Bennani-Baiti, Idriss M
PMID: 26414866
Journal: Exp Mol Pathol. 2016 Jun;100(3):402-8.
Title: EphB4 promotes the proliferation, invasion, and angiogenesis of human colorectal cancer.
Author: Lv, JingHuan|Xia, QiuYuan|Wang, JianJun|Shen, Qin|Zhang, Jin|Zhou, XiaoJun
PMID: 27072105
Journal: Mol Cell Biol. 2016 Aug 12;36(17):2246-61.
Title: KSR1 and EPHB4 Regulate Myc and PGC1beta To Promote Survival of Human Colon Tumors.
Author: McCall, Jamie L|Gehring, Drew|Clymer, Beth K|Fisher, Kurt W|Das, Binita|Kelly, David L|Kim, Hyunseok|White, Michael A|Lewis, Robert E
PMID: 27273865
Journal: Int J Mol Sci. 2017 Feb 3;18(2). pii: ijms18020307.
Title: Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery.
Author: Stammes, Marieke A|Prevoo, Hendrica A J M|Ter Horst, Meyke C|Groot, Stephanie A|Van de Velde, Cornelis J H|Chan, Alan B|de Geus-Oei, Lioe-Fee|Kuppen, Peter J K|Vahrmeijer, Alexander L|Pasquale, Elena B|Sier, Cornelis F M
PMID: 28165374
Journal: Int J Mol Sci. 2017 Jun 9;18(6). pii: ijms18061240.
Title: Right- vs. Left-Sided Metastatic Colorectal Cancer: Differences in Tumor Biology and Bevacizumab Efficacy.
Author: Ulivi, Paola|Scarpi, Emanuela|Chiadini, Elisa|Marisi, Giorgia|Valgiusti, Martina|Capelli, Laura|Casadei Gardini, Andrea|Monti, Manlio|Ruscelli, Silvia|Frassineti, Giovanni Luca|Calistri, Daniele|Amadori, Dino|Passardi, Alessandro
PMID: 28598398
Journal: Drug Deliv. 2017 Nov;24(1):1441-1452.
Title: Near infrared light mediated photochemotherapy for efficiently treating deep orthotopic tumors guided by ultrasound imaging.
Author: Wang, Zuhua|Xuan, Shaoyan|Qiu, Wenqi|Zhu, Jiang|Guo, Xiaomeng|Li, Wei|Zhang, Hanbo|Zhu, Xiuliang|Du, Yong-Zhong|You, Jian
PMID: 28942682
Journal: Acta Oncol. 2018 Aug;57(8):1043-1056.
Title: Effects of EphB4 receptor expression on colorectal cancer cells, tumor growth, vascularization and composition.
Author: Kadife, Elif|Ware, Thomas Michael Benjamin|Luwor, Rodney Brian|Chan, Steven Tuck Foo|Nurgali, Kulmira|Senior, Paul Vincent
PMID: 29368976
Journal: Clin Colorectal Cancer. 2018 Sep;17(3):e471-e488.
Title: Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study.
Author: Hanna, Diana L|Loupakis, Fotios|Yang, Dongyun|Cremolini, Chiara|Schirripa, Marta|Li, Meng|Matsusaka, Satoshi|Berger, Martin D|Miyamoto, Yuji|Zhang, Wu|Ning, Yan|Antoniotti, Carlotta|Salvatore, Lisa|Moran, Miriana|Zeger, Gary|Astrow, Stephanie H|Falcone, A
PMID: 29636300