Primary Site >> Liver Cancer

Gene >> EGR1

Journal: J Clin Invest. 1996 Jan 15;97(2):388-95.
Title: Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis.
Author: Yoo, Y D|Ueda, H|Park, K|Flanders, K C|Lee, Y I|Jay, G|Kim, S J
PMID: 8567959
Journal: J Korean Med Sci. 1998 Apr;13(2):171-8.
Title: Different protein-binding patterns in the P3 promoter region of the human insulin-like growth factor II gene in the human liver cirrhosis and hepatocellular carcinoma tissues.
Author: Seo, J H|Kim, K W|Park, B C
PMID: 9610618
Journal: Virology. 2001 May 10;283(2):167-77.
Title: Hepatitis C virus core protein transactivates insulin-like growth factor II gene transcription through acting concurrently on Egr1 and Sp1 sites.
Author: Lee, S|Park, U|Lee, Y I
PMID: 11336542
Journal: Zhonghua Yi Xue Za Zhi. 2008 May 27;88(20):1384-9.
Title: [Alteration of early growth response 1 expression in gastroenterological cancers and its biological significance].
Author: An, Juan|Guo, Rui-fang|Zhang, Liang|Geng, Pai-li|Lu, You-yong
PMID: 18953875
Journal: J Gastroenterol Hepatol. 2009 Apr;24(4):605-17.
Title: Cross-species hybridization of woodchuck hepatitis viral infection-induced woodchuck hepatocellular carcinoma using human, rat and mouse oligonucleotide microarrays.
Author: Wang, Fangjing|Kuang, Yu|Salem, Nicolas|Anderson, Paul W|Lee, Zhenghong
PMID: 19175833
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2929-32.
Title: Identifying genes for establishing a multigenic test for hepatocellular carcinoma surveillance in hepatitis C virus-positive cirrhotic patients.
Author: Archer, Kellie J|Mas, Valeria R|David, Krystle|Maluf, Daniel G|Bornstein, Karen|Fisher, Robert A
PMID: 19861515
Journal: Mol Cell Biochem. 2011 Jul;353(1-2):151-7.
Title: Alterations in the expression of genes related to NF-kappaB signaling in liver and kidney of CuZnSOD-deficient mice.
Author: Brzoska, Kamil|Sochanowicz, Barbara|Siomek, Agnieszka|Olinski, Ryszard|Kruszewski, Marcin
PMID: 21472504
Journal: Biotechnol J. 2012 Nov;7(11):1395-404.
Title: Gene network analysis leads to functional validation of pathways linked to cancer cell growth and survival.
Author: Berger, Emmanuelle|Vega, Nathalie|Vidal, Hubert|Geloen, Alain
PMID: 22930530
Journal: PLoS One. 2012;7(8):e42717.
Title: Heparin inhibits Hepatocyte Growth Factor induced motility and invasion of hepatocellular carcinoma cells through early growth response protein 1.
Author: Ozen, Evin|Gozukizil, Aysim|Erdal, Esra|Uren, Aykut|Bottaro, Donald P|Atabey, Nese
PMID: 22912725
Journal: Oncogene. 2012 Feb 16;31(7):842-57.
Title: Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/beta-catenin signaling axis.
Author: Lu, D|Han, C|Wu, T
PMID: 21743491
Journal: J Biol Chem. 2014 Aug 29;289(35):24665-79.
Title: A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation.
Author: Shan, Jixiu|Balasubramanian, Mukundh N|Donelan, William|Fu, Lingchen|Hayner, Jaclyn|Lopez, Maria-Cecilia|Baker, Henry V|Kilberg, Michael S
PMID: 25028509
Journal: Biochem Pharmacol. 2014 Oct 1;91(3):337-47.
Title: 15d-PGJ(2) decreases PGE(2) synthesis in HBx-positive liver cells by interfering EGR1 binding to mPGES-1 promoter.
Author: Liu, Chong|Chen, Siyan|Wang, Xiaoqian|Chen, Yanling|Tang, Nanhong
PMID: 25108236
Journal: Oncotarget. 2015 May 10;6(13):11547-60.
Title: Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU.
Author: Li, Xin|Yu, Jie|Brock, Malcolm V|Tao, Qian|Herman, James G|Liang, Ping|Guo, Mingzhou
PMID: 25909168
Journal: Carcinogenesis. 2015 Aug;36(8):904-13.
Title: Hepatic inflammation facilitates transcription-associated mutagenesis via AID activity and enhances liver tumorigenesis.
Author: Matsumoto, Tomonori|Shimizu, Takahiro|Nishijima, Norihiro|Ikeda, Atsuyuki|Eso, Yuji|Matsumoto, Yuko|Chiba, Tsutomu|Marusawa, Hiroyuki
PMID: 25969143
Journal: Oncotarget. 2015 Oct 13;6(31):31958-84.
Title: miR675 upregulates long noncoding RNA H19 through activating EGR1 in human liver cancer.
Author: Li, Haiyan|Li, Jiao|Jia, Song|Wu, Mengying|An, Jiahui|Zheng, Qidi|Zhang, Wei|Lu, Dongdong
PMID: 26376677
Journal: Tumour Biol. 2016 May;37(5):5751-60.
Title: Tumor suppressor NGX6 inhibits the growth and metastasis of multiple cancers.
Author: He, Shiwei|Zhong, Yancheng|Shuai, Cijun|Gao, Dan|Wei, Pingpin|Li, Guiyuan|Peng, Shuping
PMID: 26880583
Journal: PLoS One. 2016 Nov 11;11(11):e0165516.
Title: ZHX1 Promotes the Proliferation, Migration and Invasion of Cholangiocarcinoma Cells.
Author: Kwon, Ryuk-Jun|Han, Myoung-Eun|Kim, Ji-Young|Liu, Liangwen|Kim, Yun-Hak|Jung, Jin-Sup|Oh, Sae-Ock
PMID: 27835650
Journal: Sci Rep. 2016 Sep 19;6:33524.
Title: A combination hepatoma-targeted therapy based on nanotechnology: pHRE-Egr1-HSV-TK/(131)I-antiAFPMcAb-GCV/MFH.
Author: Lin, Mei|Huang, Junxing|Jiang, Xingmao|Zhang, Jia|Yu, Hong|Ye, Jun|Zhang, Dongsheng
PMID: 27642033
Journal: Biochem Biophys Res Commun. 2016 Sep 16;478(2):964-9.
Title: Insulin-like growth factor-binding protein-3 inhibits IGF-1-induced proliferation of human hepatocellular carcinoma cells by controlling bFGF and PDGF autocrine/paracrine loops.
Author: Ma, Yang|Han, Chen-Chen|Li, Yifan|Wang, Yang|Wei, Wei
PMID: 27521890
Journal: Oncotarget. 2016 Jul 19;7(29):45302-45316.
Title: EGR1 mediates miR-203a suppress the hepatocellular carcinoma cells progression by targeting HOXD3 through EGFR signaling pathway.
Author: Wang, Lumin|Sun, Hongfei|Wang, Xiaofei|Hou, Ni|Zhao, Lingyu|Tong, Dongdong|He, Kang|Yang, Yang|Song, Tusheng|Yang, Jun|Huang, Chen
PMID: 27244890
Journal: Oncol Rep. 2016 May;35(5):3068-74.
Title: GRK2 overexpression inhibits IGF1-induced proliferation and migration of human hepatocellular carcinoma cells by downregulating EGR1.
Author: Ma, Yang|Han, Chen-Chen|Huang, Qiong|Sun, Wu-Yi|Wei, Wei
PMID: 26936374
Journal: Tumour Biol. 2016 Mar;37(3):2987-98.
Title: PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection.
Author: Liao, Bo-Yi|Wang, Zheng|Hu, Jie|Liu, Wei-Feng|Shen, Zao-Zhuo|Zhang, Xin|Yu, Lei|Fan, Jia|Zhou, Jian
PMID: 26415733
Journal: J Cell Commun Signal. 2017 Jun;11(2):155-166.
Title: The regulatory role of heparin on c-Met signaling in hepatocellular carcinoma cells.
Author: Iscan, Evin|Gunes, Aysim|Korhan, Peyda|Yilmaz, Yeliz|Erdal, Esra|Atabey, Nese
PMID: 27975162
Journal: Neoplasma. 2017;64(2):216-221.
Title: Analysis of differentially co-expressed genes based on microarray data of hepatocellular carcinoma.
Author: Wang, Y|Jiang, T|Li, Z|Lu, L|Zhang, R|Zhang, D|Wang, X|Tan, J
PMID: 28043148
Journal: World J Gastroenterol. 2017 Sep 28;23(36):6639-6649.
Title: Attenuation of MET-mediated migration and invasion in hepatocellular carcinoma cells by SOCS1.
Author: Gui, Yirui|Khan, Md Gulam Musawwir|Bobbala, Diwakar|Dubois, Claire|Ramanathan, Sheela|Saucier, Caroline|Ilangumaran, Subburaj
PMID: 29085209
Journal: BMC Cancer. 2017 Dec 18;17(1):862.
Title: Gene expression, regulation of DEN and HBx induced HCC mice models and comparisons of tumor, para-tumor and normal tissues.
Author: Tang, Qin|Wang, Qi|Zhang, Qiong|Lin, Sheng-Yan|Zhu, Yanhong|Yang, Xiangliang|Guo, An-Yuan
PMID: 29254483
Journal: Hepatoma Res. 2017;3:268-277.
Title: Role of early growth response 1 in liver metabolism and liver cancer.
Author: Magee, Nancy|Zhang, Yuxia
PMID: 29607419
Journal: Cancer Res. 2018 Jan 1;78(1):51-63.
Title: CBX8 Exhibits Oncogenic Activity via AKT/beta-Catenin Activation in Hepatocellular Carcinoma.
Author: Zhang, Chris Zhiyi|Chen, Shi-Lu|Wang, Chun-Hua|He, Yang-Fan|Yang, Xia|Xie, Dan|Yun, Jing-Ping
PMID: 29066512
Journal: J Exp Clin Cancer Res. 2018 Jan 29;37(1):14.
Title: miR-3928v is induced by HBx via NF-kappaB/EGR1 and contributes to hepatocellular carcinoma malignancy by down-regulating VDAC3.
Author: Zhang, Qiaoge|Song, Ge|Yao, Lili|Liu, Yankun|Liu, Min|Li, Shengping|Tang, Hua
PMID: 29378599
Journal: Cell Biol Int. 2018 Apr 25.
Title: Effects of COL8A1 on the proliferation of muscle-derived satellite cells.
Author: Li, Xiaofan|Wang, Zhao|Tong, Huili|Yan, Yunqin|Li, Shufeng
PMID: 29696735
Journal: Med Sci Monit. 2018 May 24;24:3450-3461.
Title: Identification of Biological Targets of Therapeutic Intervention for Hepatocellular Carcinoma by Integrated Bioinformatical Analysis.
Author: Hu, Wei Qi|Wang, Wei|Fang, Di Long|Yin, Xue Feng
PMID: 29795057
Journal: Biomed Res Int. 2018 Aug 29;2018:1431396.
Title: Analysis of Transcription Factor-Related Regulatory Networks Based on Bioinformatics Analysis and Validation in Hepatocellular Carcinoma.
Author: Liu, Shui|Yao, Xiaoxiao|Zhang, Dan|Sheng, Jiyao|Wen, Xin|Wang, Qingyu|Chen, Gaoyang|Li, Zhaoyan|Du, Zhenwu|Zhang, Xuewen
PMID: 30228980