Primary Site >> Esophagus Cancer

Gene >> EGFR

Journal: Gan No Rinsho. 1989 Oct;35(12):1399-406.
Title: [Expression of the epidermal growth factor receptor in esophageal cancer].
Author: Mukaida, H|Hirai, T|Toi, M|Nakamura, T|Yamashita, Y|Kawano, K|Toge, T|Niimoto, M|Hattori, T
PMID: 2681876
Journal: Jpn J Surg. 1990 May;20(3):275-82.
Title: Expression of human epidermal growth factor and its receptor in esophageal cancer.
Author: Mukaida, H|Yamamoto, T|Hirai, T|Toi, M|Nakamura, T|Wada, T|Yamashita, Y|Kawano, K|Niimoto, M
PMID: 2193179
Journal: Int J Cancer. 1990 Jan 15;45(1):131-5.
Title: EGF and TGF-alpha, the ligands of hyperproduced EGFR in human esophageal carcinoma cells, act as autocrine growth factors.
Author: Yoshida, K|Kyo, E|Tsuda, T|Tsujino, T|Ito, M|Niimoto, M|Tahara, E
PMID: 2298497
Journal: Cancer. 1991 Jul 1;68(1):142-8.
Title: Clinical significance of the expression of epidermal growth factor and its receptor in esophageal cancer.
Author: Mukaida, H|Toi, M|Hirai, T|Yamashita, Y|Toge, T
PMID: 2049734
Journal: Nihon Kyobu Geka Gakkai Zasshi. 1992 Jan;40(1):36-42.
Title: [Studies on biological characteristics of undifferentiated carcinoma of the esophagus].
Author: Shima, I|Tomita, Y|Tou, Y|Rikitake, H|Shirouzu, G|Yamana, H|Fujita, H|Kakegawa, T|Irie, K|Morimatsu, M
PMID: 1373428
Journal: Gan To Kagaku Ryoho. 1992 Jan;19(1):20-5.
Title: [New prognostic factors in patients with esophageal squamous carcinoma].
Author: Ueda, M
PMID: 1530906
Journal: Int J Cancer. 1993 May 8;54(2):213-9.
Title: Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas.
Author: al-Kasspooles, M|Moore, J H|Orringer, M B|Beer, D G
PMID: 8098013
Journal: Tohoku J Exp Med. 1993 Oct;171(2):107-18.
Title: Intratumoral heterogeneity of DNA ploidy and regional differences in epidermal growth factor and epidermal growth factor receptor of esophageal carcinoma.
Author: Deguchi, S|Muto, Y|Kusano, T|Tomita, S|Toda, T
PMID: 8128479
Journal: Mol Carcinog. 1993;8(4):306-11.
Title: Correlation of p53 mutations with epidermal growth factor receptor overexpression and absence of mdm2 amplification in human esophageal carcinomas.
Author: Esteve, A|Lehman, T|Jiang, W|Weinstein, I B|Harris, C C|Ruol, A|Peracchia, A|Montesano, R|Hollstein, M
PMID: 8280379
Journal: Eur Arch Otorhinolaryngol. 1993;250(7):392-5.
Title: erbB-3, a third member of the erbB/epidermal growth factor receptor gene family: its expression in head and neck cancer cell lines.
Author: Issing, W J|Heppt, W J|Kastenbauer, E R
PMID: 8286103
Journal: Int J Cancer. 1993 Sep 30;55(3):364-70.
Title: Growth-regulatory mechanism of two human esophageal-cancer cell lines in protein-free conditions.
Author: Iihara, K|Shiozaki, H|Oku, K|Tahara, H|Doki, Y|Oka, H|Kadowaki, T|Iwazawa, T|Inoue, M|Mori, T
PMID: 8375919
Journal: Cancer. 1993 May 15;71(10):2902-9.
Title: Prognostic significance of transforming growth factor-alpha in human esophageal carcinoma. Implication for the autocrine proliferation.
Author: Iihara, K|Shiozaki, H|Tahara, H|Kobayashi, K|Inoue, M|Tamura, S|Miyata, M|Oka, H|Doki, Y|Mori, T
PMID: 8490817
Journal: J Cancer Res Clin Oncol. 1993;119(7):401-7.
Title: Expression of growth factors and their receptors in human esophageal carcinomas: regulation of expression by epidermal growth factor and transforming growth factor alpha.
Author: Yoshida, K|Kuniyasu, H|Yasui, W|Kitadai, Y|Toge, T|Tahara, E
PMID: 8491760
Journal: J Gastroenterol. 1994 Oct;29(5):616-20.
Title: Serum levels of c-erbB-2 protein in digestive diseases.
Author: Motoo, Y|Sawabu, N|Yamaguchi, Y|Mouri, I|Yamakawa, O|Watanabe, H|Ohta, H|Okai, T|Makino, H
PMID: 7528080
Journal: Curr Probl Cancer. 1994 Jul-Aug;18(4):189-247.
Title: Esophageal cancer.
Author: Coia, L R|Sauter, E R
PMID: 7533069
Journal: Zhonghua Zhong Liu Za Zhi. 1994 Nov;16(6):407-10.
Title: [Alterations of oncogenes in human fetal esophageal epithelium induced by N-methylbenzylnitrosamine (NMBzA)].
Author: Guo, Y J|Lu, S X|Liang, Y Y
PMID: 7720492
Journal: Cancer. 1994 Aug 1;74(3):795-804.
Title: Epidermal growth factor receptor overexpression in esophageal carcinoma. An immunohistochemical study correlated with clinicopathologic findings and DNA amplification.
Author: Itakura, Y|Sasano, H|Shiga, C|Furukawa, Y|Shiga, K|Mori, S|Nagura, H
PMID: 8039107
Journal: Oncol Rep. 1995 May;2(3):381-5.
Title: Epidermal growth-factor receptors and erbb2 protein expression in esophageal cancer and normal mucosa.
Author: Dittadi, R|Ruol, A|Gion, M|Segalin, A|Panozzo, M|Brazzale, A|Meo, S|Ancona, E|Peracchia, A
PMID: 21597745
Journal: Am J Surg Pathol. 1996 Apr;20(4):453-61.
Title: Basaloid-squamous carcinoma of the esophagus. A clinicopathologic, DNA ploidy, and immunohistochemical study of seven cases.
Author: Abe, K|Sasano, H|Itakura, Y|Nishihira, T|Mori, S|Nagura, H
PMID: 8604812
Journal: Gan To Kagaku Ryoho. 1996 Jul;23(8):972-81.
Title: [Prognostic factors for esophageal cancer--from the viewpoint of molecular biology].
Author: Shimada, Y|Imamura, M
PMID: 8687232
Journal: Nihon Rinsho. 1996 Apr;54(4):1060-5.
Title: [Genetic events during development of esophageal squamous cell carcinoma].
Author: Sasaki, H|Watanabe, H|Terada, M
PMID: 8920674
Journal: Scand J Gastroenterol. 1997 Aug;32(8):824-8.
Title: Effect of suramin on human esophageal cancer cells in vitro and in vivo.
Author: Shin, R|Naomoto, Y|Kamikawa, Y|Tanaka, N|Orita, K
PMID: 9282976
Journal: Cancer Invest. 1997;15(5):411-5.
Title: Gene amplification of int-2 and erbB in human esophageal cancer: relationship to clinicopathological variables.
Author: Suzuki, H|Abo, S|Kitamura, M|Hashimoto, M|Izumi, K|Terada, K|Sugiyama, T
PMID: 9316622
Journal: Dis Esophagus. 1998 Oct;11(4):221-5.
Title: Clinical results of transhiatal esophagectomy for carcinoma of the lower thoracic esophagus according to biological markers.
Author: Hirai, T|Kuwahara, M|Yoshida, K|Kagawa, Y|Hihara, J|Yamashita, Y|Toge, T
PMID: 10071802
Journal: J Cancer Res Clin Oncol. 1999;125(1):47-54.
Title: Expression of epidermal growth factor receptor and CD44 splicing variants sharing exons 6 and 9 on gastric and esophageal carcinomas: a two-color flow-cytometric analysis.
Author: Koyama, S|Maruyama, T|Adachi, S
PMID: 10037277
Journal: World J Surg. 1999 Oct;23(10):1010-8.
Title: Concomitant analysis of the epidermal growth factor receptor family in esophageal cancer: overexpression of epidermal growth factor receptor mRNA but not of c-erbB-2 and c-erbB-3.
Author: Friess, H|Fukuda, A|Tang, W H|Eichenberger, A|Furlan, N|Zimmermann, A|Korc, M|Buchler, M W
PMID: 10512940
Journal: Recent Results Cancer Res. 2000;155:73-87.
Title: What's new in imaging? New magnetic resonance imaging of esophageal cancer using an endoluminal surface coil and antibody-coated magnetite particles.
Author: Ozawa, S|Imai, Y|Suwa, T|Kitajima, M
PMID: 10693240
Journal: Oncogene. 2000 Mar 23;19(13):1665-75.
Title: Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway.
Author: Leu, C M|Chang, C|Hu, C
PMID: 10763823
Journal: J Biol Chem. 2000 Oct 6;275(40):30934-42.
Title: Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.
Author: Okano, J|Gaslightwala, I|Birnbaum, M J|Rustgi, A K|Nakagawa, H
PMID: 10908564
Journal: Ann Thorac Surg. 2001 Sep;72(3):859-66.
Title: Tumor marker expression is predictive of survival in patients with esophageal cancer.
Author: Aloia, T A|Harpole, D H Jr|Reed, C E|Allegra, C|Moore, M B|Herndon, J E 2nd|D'Amico, T A
PMID: 11565671
Journal: J Gastroenterol Hepatol. 2002 Feb;17 Suppl:S172-5.
Title: Predictive factors for success of neo-adjuvant therapy in upper gastrointestinal cancer.
Author: Walsh, Thomas N|Grannell, Mark|Mansoor, Shabaz
PMID: 12000603
Journal: Nihon Geka Gakkai Zasshi. 2002 Jun;103(6):457-62.
Title: [Molecular alterations in esophageal cancer].
Author: Ozawa, Soji|Kitagawa, Yuko|Kitajima, Masaki
PMID: 12094695
Journal: J Gastroenterol. 2002;37(7):497-503.
Title: Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1.
Author: Ichiba, Makoto|Miyazaki, Yoshiji|Kitamura, Shinji|Kiyohara, Tatsuya|Shinomura, Yasuhisa|Matsuzawa, Yuji
PMID: 12162406
Journal: Onkologie. 2004 Feb;27(1):17-21.
Title: Recent results in understanding molecular pathways in the medical treatment of esophageal and gastric cancer.
Author: Sutter, A P|Zeitz, M|Scherubl, H
PMID: 15007244
Journal: Anticancer Res. 2004 Mar-Apr;24(2B):811-9.
Title: Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro.
Author: Akimoto, Tetsuo|Nonaka, Tetsuo|Harashima, Koichi|Ishikawa, Hitoshi|Sakurai, Hideyuki|Mitsuhashi, Norio
PMID: 15161032
Journal: Cancer Res. 2004 Nov 1;64(21):7711-23.
Title: Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3.
Author: Takaoka, Munenori|Harada, Hideki|Andl, Claudia D|Oyama, Kenji|Naomoto, Yoshio|Dempsey, Kelly L|Klein-Szanto, Andres J|El-Deiry, Wafik S|Grimberg, Adda|Nakagawa, Hiroshi
PMID: 15520175
Journal: Ai Zheng. 2005 Feb;24(2):241-5.
Title: [Expressions of epithelial growth factor receptor and E-cadherin in esophageal carcinoma and their correlation].
Author: Fu, Jian-Hua|Yang, Da-Kuan|Huang, Yun-Chao|Hu, Guo-Qiang
PMID: 15694044
Journal: J Am Coll Surg. 2005 Mar;200(3):336-44.
Title: Downregulation of TS, DPD, ERCC1, GST-Pi, EGFR, and HER2 gene expression after neoadjuvant three-modality treatment in patients with esophageal cancer.
Author: Schneider, Sylke|Uchida, Kazumi|Brabender, Jan|Baldus, Stephan E|Yochim, JiMin|Danenberg, Kathleen D|Salonga, Dennis|Chen, Pei|Tsao-Wei, Denice|Groshen, Susan|Hoelscher, Arnulf H|Schneider, Paul M|Danenberg, Peter V
PMID: 15737843
Journal: Ann Oncol. 2005 Nov;16(11):1740-8. Epub 2005 Jun 24.
Title: Novel targeted therapies in the treatment of gastric and esophageal cancer.
Author: Tabernero, J|Macarulla, T|Ramos, F J|Baselga, J
PMID: 15980157
Journal: FEBS Lett. 2005 Aug 1;579(19):4069-75.
Title: ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma.
Author: Teraishi, Fuminori|Kagawa, Shunsuke|Watanabe, Takanori|Tango, Yasuhisa|Kawashima, Takeshi|Umeoka, Tatsuo|Nisizaki, Masahiko|Tanaka, Noriaki|Fujiwara, Toshiyoshi
PMID: 16023108
Journal: Cancer Res. 2005 Sep 1;65(17):8049-56.
Title: Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells.
Author: Hou, Zhe|Sang, Shengmin|You, Hui|Lee, Mao-Jung|Hong, Jungil|Chin, Khew-Voon|Yang, Chung S
PMID: 16140980
Journal: World J Gastroenterol. 2005 Nov 7;11(41):6538-42.
Title: Dual effects of 8-Br-cAMP on differentiation and apoptosis of human esophageal cancer cell line Eca-109.
Author: Wang, Hong-Mei|Zheng, Nai-Gang|Wu, Jing-Lan|Gong, Cui-Cui|Wang, Yi-Ling
PMID: 16425431
Journal: Int J Cancer. 2006 Apr 1;118(7):1814-22.
Title: Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer.
Author: Sutter, Andreas P|Hopfner, Michael|Huether, Alexander|Maaser, Kerstin|Scherubl, Hans
PMID: 16217753
Journal: Cancer Biol Ther. 2006 Feb;5(2):152-5. Epub 2006 Feb 10.
Title: Gefitinib-sensitizing mutation in esophageal carcinoma cell line Kyse450.
Author: Guo, Mingzhou|Liu, Shuang|Herman, James G|Zhuang, Hui|Lu, Fengmin
PMID: 16357520
Journal: J Surg Res. 2006 Jul;134(1):1-9. Epub 2006 Feb 20.
Title: Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model.
Author: Sui, Guoping|Bonde, Pramod|Dhara, Surajit|Broor, Apoorv|Wang, Jiaai|Marti, Guy|Feldmann, Georg|Duncan, Mark|Montgomery, Elizabeth|Maitra, Anirban|Harmon, John W
PMID: 16488438
Journal: Acta Med Okayama. 2006 Feb;60(1):25-34.
Title: Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro.
Author: Taira, Naruto|Doihara, Hiroyoshi|Oota, Tetsuya|Hara, Fumikata|Shien, Tadahiko|Takahashi, Hirotoshi|Yoshitomi, Seiji|Ishibe, Youichi|Shimizu, Nobuyoshi
PMID: 16508686
Journal: J Clin Oncol. 2006 Apr 1;24(10):1612-9.
Title: Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.
Author: Janmaat, Maarten L|Gallegos-Ruiz, Marielle I|Rodriguez, Jose A|Meijer, Gerrit A|Vervenne, Walter L|Richel, Dick J|Van Groeningen, Cees|Giaccone, Giuseppe
PMID: 16575012
Journal: Crit Rev Oncol Hematol. 2006 Aug;59(2):128-38. Epub 2006 Jul 10.
Title: Novel targets in gastric and esophageal cancer.
Author: Valverde, Claudia Maria|Macarulla, Teresa|Casado, Esther|Ramos, Francisco Javier|Martinelli, Erika|Tabernero, Josep
PMID: 16829119
Journal: Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4283-7.
Title: Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas.
Author: Kwak, Eunice L|Jankowski, Janusz|Thayer, Sarah P|Lauwers, Gregory Y|Brannigan, Brian W|Harris, Patricia L|Okimoto, Ross A|Haserlat, Sara M|Driscoll, David R|Ferry, David|Muir, Beth|Settleman, Jeff|Fuchs, Charles S|Kulke, Matthew H|Ryan, David P|Clark, Jef
PMID: 16857803
Journal: Cancer Res. 2006 Nov 1;66(21):10415-24.
Title: Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras.
Author: Kim, Seok-Hyun|Nakagawa, Hiroshi|Navaraj, Arunasalam|Naomoto, Yoshio|Klein-Szanto, Andres J P|Rustgi, Anil K|El-Deiry, Wafik S
PMID: 17079462
Journal: Eur J Surg Oncol. 2007 Feb;33(1):44-8. Epub 2006 Dec 4.
Title: Identification of EGFR mutations in esophageal cancer.
Author: Sudo, T|Mimori, K|Nagahara, H|Utsunomiya, T|Fujita, H|Tanaka, Y|Shirouzu, K|Inoue, H|Mori, M
PMID: 17142003
Journal: Oncol Rep. 2007 Jan;17(1):161-7.
Title: Neutrophil elastase induces cell proliferation and migration by the release of TGF-alpha, PDGF and VEGF in esophageal cell lines.
Author: Wada, Yoshiyuki|Yoshida, Kazuhiro|Tsutani, Yasuhiro|Shigematsu, Hideaki|Oeda, Mamoru|Sanada, Yuichi|Suzuki, Takahisa|Mizuiri, Hirozumi|Hamai, Yoichi|Tanabe, Kazuaki|Ukon, Kei|Hihara, Jun
PMID: 17143494
Journal: Oncol Rep. 2007 Apr;17(4):887-93.
Title: The pan-erbB tyrosine kinase inhibitor CI-1033 inhibits human esophageal cancer cells in vitro and in vivo.
Author: Ako, E|Yamashita, Y|Ohira, M|Yamazaki, M|Hori, T|Kubo, N|Sawada, T|Hirakawa, K
PMID: 17342332
Journal: Pathobiology. 2007;74(1):15-21.
Title: Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma.
Author: Hoshino, Mina|Fukui, Hirokazu|Ono, Yuko|Sekikawa, Akira|Ichikawa, Kazuhito|Tomita, Shigeki|Imai, Yasuo|Imura, Johji|Hiraishi, Hideyuki|Fujimori, Takahiro
PMID: 17496429
Journal: JAMA. 2007 Jul 4;298(1):70-82.
Title: Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas.
Author: Karamouzis, Michalis V|Grandis, Jennifer R|Argiris, Athanassios
PMID: 17609492
Journal: Cancer Biol Ther. 2007 Oct;6(10):1553-8. Epub 2007 Jul 7.
Title: Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer.
Author: Jain, Meenu|Kumar, Shaleen|Upadhyay, Rohit|Lal, Puneeta|Tiwari, Anu|Ghoshal, Uday C|Mittal, Balraj
PMID: 17912028
Journal: Genes Dev. 2007 Nov 1;21(21):2788-803.
Title: The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.
Author: Okawa, Takaomi|Michaylira, Carmen Z|Kalabis, Jiri|Stairs, Douglas B|Nakagawa, Hiroshi|Andl, Claudia D|Johnstone, Cameron N|Klein-Szanto, Andres J|El-Deiry, Wafik S|Cukierman, Edna|Herlyn, Meenhard|Rustgi, Anil K
PMID: 17974918
Journal: Oncology. 2007;73(5-6):281-9.
Title: Epidermal growth factor receptor-directed therapy in esophageal cancer.
Author: Pande, A U|Iyer, R V|Rani, A|Maddipatla, S|Yang, G Y|Nwogu, C E|Black, J D|Levea, C M|Javle, M M
PMID: 18477853
Journal: Bull Cancer. 2008 Jan;95(1):117-20.
Title: [News in digestive oncology].
Author: Michel, Pierre|Di Fiore, Frederic
PMID: 18230577
Journal: J Pharmacol Exp Ther. 2008 Jul;326(1):69-75.
Title: Epidermal growth factor-induced esophageal cancer cell proliferation requires transactivation of beta-adrenoceptors.
Author: Liu, Xuan|Wu, William K K|Yu, Le|Li, Zhi J|Sung, Joseph J Y|Zhang, Shu T|Cho, Chi H
PMID: 18369180
Journal: Gastroenterol Clin Biol. 2008 Jun-Jul;32(6-7):567-77.
Title: Predictive factors of the response to chemoradiotherapy in esophageal cancer.
Author: Ressiot, E|Dahan, L|Liprandi, A|Giorgi, R|Djourno, X-B|Padovani, L|Alibert, S|Ries, P|Laquiere, A|Laugier, R|Thomas, P|Seitz, J-F
PMID: 18555630
Journal: Oncol Res. 2008;17(4):167-74.
Title: Interaction of EGFR 497Arg>Lys with EGF +61A>G polymorphism: modulation of risk in esophageal cancer.
Author: Upadhyay, Rohit|Jain, Meenu|Kumar, Shaleen|Ghoshal, Uday Chand|Mittal, Balraj
PMID: 18773861
Journal: Am J Clin Oncol. 2008 Aug;31(4):329-34.
Title: Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: tissue effect predicts clinical response.
Author: Javle, Milind|Pande, Amitkumar|Iyer, Renuka|Yang, Gary|LeVea, Charles|Wilding, Gregory|Black, Jennifer|Nava, Hector|Nwogu, Chukwumere
PMID: 18845990
Journal: APMIS. 2008 Dec;116(12):1097-106.
Title: Enhanced phosphorylation of the epidermal growth factor receptor at the site of tyrosine 992 in esophageal carcinomas.
Author: Miyawaki, Michiyo|Hijiya, Naoki|Tsukamoto, Yoshiyuki|Nakada, Chisato|Kawahara, Katsunobu|Moriyama, Masatsugu
PMID: 19133013
Journal: Eur J Cardiothorac Surg. 2009 Apr;35(4):699-705.
Title: Correlations between selected tumor markers and fluorodeoxyglucose maximal standardized uptake values in esophageal cancer.
Author: Taylor, Matthew D|Smith, Philip W|Brix, William K|Wick, Mark R|Theodosakis, Nicholas|Swenson, Brian R|Kozower, Benjamin D|Jones, David R
PMID: 19136271
Journal: J Hematol Oncol. 2009 Feb 23;2:9.
Title: Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology.
Author: Javle, Milind|Hsueh, Chung-Tsen
PMID: 19236713
Journal: Dis Esophagus. 2009;22(6):496-504.
Title: Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis.
Author: Boone, J|van Hillegersberg, R|Offerhaus, G J A|van Diest, P J|Borel Rinkes, I H M|Ten Kate, F J W
PMID: 19302210
Journal: Oncol Rep. 2009 Jun;21(6):1489-94.
Title: Clinical significance of the gene expression profile in residual tumor cells after neoadjuvant chemo-radiotherapy for esophageal cancer.
Author: Tanaka, Koji|Otake, Kohhei|Mohri, Yasuhiko|Ohi, Masaki|Yokoe, Takeshi|Toiyama, Yuji|Miki, Chikao|Tonouchi, Hitoshi|Kusunoki, Masato
PMID: 19424628
Journal: Expert Opin Emerg Drugs. 2009 Jun;14(2):329-39.
Title: Emerging drugs for esophageal cancer.
Author: Homs, Marjolein Y V|Voest, Emile E|Siersema, Peter D
PMID: 19453287
Journal: J Oncol. 2009;2009:804108.
Title: Anti-EGFR-Targeted Therapy for Esophageal and Gastric Cancers: An Evolving Concept.
Author: Dragovich, Tomislav|Campen, Christopher
PMID: 19636422
Journal: Radiother Oncol. 2009 Dec;93(3):468-73.
Title: Reverse resistance to radiation in KYSE-150R esophageal carcinoma cell after epidermal growth factor receptor signal pathway inhibition by cetuximab.
Author: Jing, Zhao|Gong, Ling|Xie, Cong-Ying|Zhang, Li|Su, Hua-Fang|Deng, Xia|Wu, Shi-Xiu
PMID: 19744737
Journal: J Cancer Res Clin Oncol. 2010 Apr;136(4):587-94.
Title: Expression of nucleostemin, epidermal growth factor and epidermal growth factor receptor in human esophageal squamous cell carcinoma tissues.
Author: Zhang, Gongyuan|Zhang, Qiao|Zhang, Qinxian|Yin, Lei|Li, Shenglei|Cheng, Kuisheng|Zhang, Yunhan|Xu, Honghui|Wu, Weidong
PMID: 19823871
Journal: Int J Oncol. 2010 Jan;36(1):19-27.
Title: A novel pharmacodynamic approach to assess and predict tumor response to the epidermal growth factor receptor inhibitor gefitinib in patients with esophageal cancer.
Author: Altiok, Soner|Mezzadra, Heather|Jagannath, Sanjay|Tsottles, Nancy|Rudek, Michelle A|Abdallah, Nadia|Berman, David|Forastiere, Arlene|Gibson, Michael K
PMID: 19956829
Journal: Int J Cancer. 2010 Sep 1;127(5):1197-208.
Title: Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways.
Author: Lyros, Orestis|Mueller, Annett|Heidel, Florian|Schimanski, Carl C|Gockel, Ines|Galle, Peter R|Lang, Hauke|Moehler, Markus
PMID: 20039326
Journal: BMC Gastroenterol. 2010 Feb 17;10:20.
Title: Chromosomal imbalances are uncommon in chagasic megaesophagus.
Author: Bellini, Marilanda F|Manzato, Antonio J|Silva, Ana E|Varella-Garcia, Marileila
PMID: 20163722
Journal: Cell Mol Life Sci. 2010 Oct;67(19):3313-29.
Title: Specificity protein 1 regulates fascin expression in esophageal squamous cell carcinoma as the result of the epidermal growth factor/extracellular signal-regulated kinase signaling pathway activation.
Author: Lu, Xiao-Feng|Li, En-Min|Du, Ze-Peng|Xie, Jian-Jun|Guo, Zhang-Yan|Gao, Shu-Ying|Liao, Lian-Di|Shen, Zhong-Ying|Xie, Dong|Xu, Li-Yan
PMID: 20502940
Journal: Carcinogenesis. 2010 Aug;31(8):1344-53.
Title: Insulin-like growth factor-binding protein-3 promotes transforming growth factor-{beta}1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells.
Author: Natsuizaka, Mitsuteru|Ohashi, Shinya|Wong, Gabrielle S|Ahmadi, Azal|Kalman, Ross A|Budo, Daniela|Klein-Szanto, Andres J|Herlyn, Meenhard|Diehl, J Alan|Nakagawa, Hiroshi
PMID: 20513670
Journal: Cancer Genet Cytogenet. 2010 Jul 15;200(2):120-6.
Title: Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array--comparative genomic hybridization.
Author: Isinger-Ekstrand, Anna|Johansson, Jan|Ohlsson, Mattias|Francis, Princy|Staaf, Johan|Jonsson, Mats|Borg, Ake|Nilbert, Mef
PMID: 20620594
Journal: J Clin Oncol. 2010 Sep 1;28(25):3965-72.
Title: Phase I trial of the irreversible EGFR and HER2 kinase inhibitor BIBW 2992 in patients with advanced solid tumors.
Author: Yap, Timothy A|Vidal, Laura|Adam, Jan|Stephens, Peter|Spicer, James|Shaw, Heather|Ang, Jooern|Temple, Graham|Bell, Susan|Shahidi, Mehdi|Uttenreuther-Fischer, Martina|Stopfer, Peter|Futreal, Andrew|Calvert, Hilary|de Bono, Johann S|Plummer, Ruth
PMID: 20679611
Journal: J Gastroenterol Hepatol. 2011 Feb;26(2):382-90.
Title: Aberrant expression of epidermal growth factor receptor and its interaction with protein kinase C delta in inflammation associated neoplastic transformation of human esophageal epithelium in high risk populations.
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Journal: Int J Cancer. 2011 Nov 15;129(10):2408-16.
Title: Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody-dependent cellular cytotoxicity of EGFR- and HER2-overexpressing esophageal cancer cell lines.
Author: Mimura, Kousaku|Kono, Koji|Maruyama, Takanori|Watanabe, Mitsuaki|Izawa, Shinichiro|Shiba, Shugo|Mizukami, Yoshiki|Kawaguchi, Yoshihiko|Inoue, Masayuki|Kono, Tetsuo|Choudhury, Aniruddha|Kiessling, Rolf|Fujii, Hideki
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Journal: Ann Surg Oncol. 2011 Jul;18(7):2066-73.
Title: Polymorphism in epidermal growth factor receptor intron 1 predicts prognosis of patients with esophageal cancer after chemoradiation and surgery.
Author: Lee, Jang-Ming|Yang, Shi-Yi|Yang, Pei-Wen|Shun, Chia-Tung|Wu, Ming-Tsang|Hsu, Chih-Hung|Lin, Chia-Chi|Cheng, Jason Chia-Hsien|Wang, Ying-Hao|Chuang, Tzu-Hsuen|Chen, Jin-Shing|Hsu, Hsao-Hsun|Huang, Pei-Ming|Kuo, Shuenn-Wen|Lee, Yung-Chie
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Journal: Cancer. 2011 Apr 1;117(7):1409-14.
Title: A phase 2 trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus.
Author: Ilson, David H|Kelsen, David|Shah, Manish|Schwartz, Gary|Levine, Douglas A|Boyd, Jeff|Capanu, Marinela|Miron, Benjamin|Klimstra, David
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Journal: Nanotechnology. 2011 Jun 3;22(22):225703.
Title: Ultra-small particles of iron oxide as peroxidase for immunohistochemical detection.
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Journal: Mod Pathol. 2011 Sep;24(9):1177-90.
Title: The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa-associated adenocarcinoma.
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Journal: Dis Esophagus. 2011 Jul;24(5):374-80.
Title: Identification of EGFR and KRAS mutations in Chinese patients with esophageal squamous cell carcinoma.
Author: Liu, Q-W|Fu, J-H|Luo, K-J|Yang, H-X|Wang, J-Y|Hu, Y|Yang, H|Bella, E
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Journal: J Transl Med. 2011 Sep 22;9:157.
Title: An novel role of sphingosine kinase-1 (SPHK1) in the invasion and metastasis of esophageal carcinoma.
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Journal: Eur J Med Res. 2011 Oct 10;16(10):437-44.
Title: Trimodal therapy in squamous cell carcinoma of the esophagus.
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Journal: Am J Hum Genet. 2012 Feb 10;90(2):340-6.
Title: RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome.
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Journal: Oncol Rep. 2012 May;27(5):1639-45.
Title: Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma.
Author: Guo, Xiao-Fang|Zhu, Xiao-Fei|Zhong, Gen-Shen|Deng, Bao-Guo|Gao, Zhi-Tao|Wang, Hui
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Journal: Cancer Chemother Pharmacol. 2012 May;69(5):1323-32.
Title: Pingyangmycin downregulates the expression of EGFR and enhances the effects of cetuximab on esophageal cancer cells and the xenograft in athymic mice.
Author: Gong, Jian-hua|Liu, Xiu-jun|Li, Yi|Zhen, Yong-su
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Journal: Oncol Rep. 2012 Jun;27(6):1967-75.
Title: microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor.
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Journal: Ann Thorac Surg. 2012 Apr;93(4):1101-6.
Title: Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma.
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Journal: Curr Oncol Rep. 2012 Aug;14(4):342-9.
Title: Current developments in the management of locally advanced esophageal cancer.
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Journal: Cancer Biol Ther. 2012 Jun;13(8):600-5.
Title: Treatment of malignant, non-resectable, epithelial origin esophageal tumours with the humanized anti-epidermal growth factor antibody nimotuzumab combined with radiation therapy and chemotherapy.
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Journal: Front Oncol. 2012 Apr 10;2:31.
Title: Radiotherapy and erlotinib combined: review of the preclinical and clinical evidence.
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Journal: Pathol Res Pract. 2012 Jul 15;208(7):398-404.
Title: pERK activation in esophageal carcinomas: clinicopathological associations.
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Journal: Cancer Res. 2012 Sep 1;72(17):4383-93. Epub 2012 Jul 2.
Title: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
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Journal: PLoS One. 2012;7(8):e41655.
Title: High-throughput genotyping in metastatic esophageal squamous cell carcinoma identifies phosphoinositide-3-kinase and BRAF mutations.
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Title: Trastuzumab anti-tumor efficacy in patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mouse models.
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Journal: Curr Top Med Chem. 2012;12(15):1678-82.
Title: Targetting esophageal and gastric cancers with monoclonal antibodies.
Author: Norguet, Emmanuelle|Dahan, Laetitia|Seitz, Jean-Francois
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Journal: Pathologe. 2012 Nov;33 Suppl 2:253-7.
Title: [Update on Barrett esophagus and Barrett carcinoma].
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Journal: Tumori. 2012 Jul-Aug;98(4):451-7.
Title: Neoadjuvant chemo-radiotherapy for locally advanced esophageal cancer: a monocentric study.
Author: Schena, Marina|La Rovere, Erika|Solerio, Dino|Bustreo, Sara|Barone, Carla|Daniele, Lorenzo|Buffoni, Lucio|Bironzo, Paolo|Sapino, Anna|Gasparri, Guido|Ciuffreda, Libero|Ricardi, Umberto
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Journal: Recent Results Cancer Res. 2012;196:107-13.
Title: Adenocarcinoma of the GEJ: gastric or oesophageal cancer?
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Journal: Dis Esophagus. 2013 Jul;26(5):487-95.
Title: Lapatinib, a dual inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2, potentiates the antitumor effects of cisplatin on esophageal carcinoma.
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Journal: Lasers Med Sci. 2013 Feb;28(2):605-14.
Title: The effects of Photofrin-mediated photodynamic therapy on the modulation of EGFR in esophageal squamous cell carcinoma cells.
Author: Yang, Pei-Wen|Hung, Mien-Chie|Hsieh, Ching-Yueh|Tung, En-Chi|Wang, Ying-Hao|Tsai, Jui-Chang|Lee, Jang-Ming
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Journal: Oncol Lett. 2013 Jan;5(1):19-24. Epub 2012 Oct 24.
Title: Role of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of esophageal carcinoma and the suggested mechanisms of action.
Author: Xu, Yaping|Sheng, Liming|Mao, Weimin
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Journal: Bioconjug Chem. 2013 Feb 20;24(2):167-75.
Title: Synthesis and characterization of anti-EGFR fluorescent nanoparticles for optical molecular imaging.
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Journal: J Thorac Oncol. 2013 Jun;8(6):673-84.
Title: Chemotherapeutic and targeted strategies for locally advanced and metastatic esophageal cancer.
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Journal: Curr Opin Oncol. 2013 Jul;25(4):417-24.
Title: Esophageal carcinoma: are modern targeted therapies shaking the rock?
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Journal: Expert Opin Emerg Drugs. 2013 Jun;18(2):219-30.
Title: Emerging tyrosine kinase inhibitors for esophageal cancer.
Author: Ku, Geoffrey Y|Ilson, David H
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Journal: Anticancer Res. 2013 Jun;33(6):2401-8.
Title: Sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor requires E-cadherin in esophageal cancer and malignant pleural mesothelioma.
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Journal: Expert Opin Ther Targets. 2013 Oct;17(10):1179-85.
Title: Epidermal growth factor receptor: an important target in esophageal cancer.
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Journal: Eur J Clin Invest. 2013 Dec;43(12):1233-9.
Title: Distinct genetic aberrations in oesophageal adeno and squamous carcinoma.
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Journal: Anticancer Res. 2013 Oct;33(10):4139-55.
Title: Epidermal growth factor receptor (EGFR)-targeted therapies in esophagogastric cancer.
Author: Ayyappan, Sabarish|Prabhakar, Dhivya|Sharma, Neelesh
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Journal: Onco Targets Ther. 2013 Nov 6;6:1589-96.
Title: Nimotuzumab combined with radiotherapy for esophageal cancer: preliminary study of a Phase II clinical trial.
Author: Liang, Jun|E, Mingyan|Wu, Gang|Zhao, Lujun|Li, Xia|Xiu, Xia|Li, Ning|Chen, Bo|Hui, Zhouguang|Lv, Jima|Fang, Hui|Tang, Yu|Bi, Nan|Wang, Wenqing|Zhai, Yirui|Li, Tao|Chen, Dongfu|Zou, Shuangmei|Lu, Ning|Perez-Rodriguez, Rolando|Zheng, Junqi|Wang, Luhua
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Journal: PLoS One. 2013 Nov 28;8(11):e81897.
Title: Incidence and risk of treatment-related mortality with anti-epidermal growth factor receptor monoclonal antibody in cancer patients: a meta-analysis of 21 randomized controlled trials.
Author: Li, Xing|Shan, Bao-En|Wang, Juan|Xing, Lian-Ping|Guo, Xiao-Jin|Zhang, Yue-Hua|Shi, Peng-Hui|Wang, Zhi-Yu
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Journal: Target Oncol. 2014 Mar;9(1):43-52.
Title: EGFR intron-1 CA repeat polymorphism is a predictor of relapse and survival in complete resected only surgically treated esophageal cancer.
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Journal: Clin Chem Lab Med. 2014 Feb;52(2):243-51.
Title: Enrichment and enumeration of circulating tumor cells by efficient depletion of leukocyte fractions.
Author: Wu, Shiyang|Liu, Zhiming|Liu, Suyan|Lin, Li|Yang, Weiwei|Xu, Jiasen
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Journal: Int J Cancer. 2014 Oct 1;135(7):1517-30.
Title: EGFR, HER2 and HER3 dimerization patterns guide targeted inhibition in two histotypes of esophageal cancer.
Author: Fichter, Christiane Daniela|Timme, Sylvia|Braun, Julia Alexandra|Gudernatsch, Verena|Schopflin, Anja|Bogatyreva, Lioudmilla|Geddert, Helene|Faller, Gerhard|Klimstra, David|Tang, Laura|Hauschke, Dieter|Werner, Martin|Lassmann, Silke
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Journal: Crit Rev Oncol Hematol. 2014 Aug;91(2):186-96.
Title: Targeted therapies in metastatic esophageal cancer: advances over the past decade.
Author: Mohamed, Amr|El-Rayes, Bassel|Khuri, Fadlo R|Saba, Nabil F
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Journal: PLoS One. 2014 Mar 24;9(3):e92986.
Title: An EGFR/HER2-Bispecific and enediyne-energized fusion protein shows high efficacy against esophageal cancer.
Author: Guo, Xiao-Fang|Zhu, Xiao-Fei|Yang, Wan-Cai|Zhang, Sheng-Hua|Zhen, Yong-Su
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Journal: Am Soc Clin Oncol Educ Book. 2014:e172-8.
Title: New directions in perioperative management of locally advanced esophagogastric cancer.
Author: Burtness, Barbara|Ilson, David|Iqbal, Syma
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Journal: Oncol Rep. 2014 Sep;32(3):1188-92.
Title: Cetuximab inhibits cisplatin-induced activation of EGFR signaling in esophageal squamous cell carcinoma.
Author: Kwon, Junhye|Yoon, Hyeon-Joon|Kim, Ji-Hee|Lee, Tae Sup|Song, In Ho|Lee, Hae Won|Kang, Moon Chul|Park, Jong Ho
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Journal: Lab Invest. 2014 Aug;94(8):917-26.
Title: Establishment and characterization of esophageal squamous cell carcinoma patient-derived xenograft mouse models for preclinical drug discovery.
Author: Zhang, Jingchuan|Jiang, Dongxian|Li, Xiaojing|Lv, Jing|Xie, Liang|Zheng, Li|Gavine, Paul R|Hu, Qin|Shi, Yuan|Tan, Lijie|Ge, Di|Xu, Songtao|Li, Leon|Zhu, Lifang|Hou, Yingyong|Wang, Qun
PMID: 24999713
Journal: Zhonghua Zhong Liu Za Zhi. 2014 May;36(5):346-50.
Title: [Detection and significance of epidermal growth factor receptor mutation in esophageal, esophagogastric junction and gastric cancers].
Author: Lyu, Xiao|Huang, Jing|Liu, Jian|Wang, Wenna|Su, Yiqun|Zhang, Wen|Sun, Yongkun|Ying, Jianming|Wang, Jinwan|Sun, Yan
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Journal: Genet Mol Res. 2014 Jul 24;13(3):5413-25.
Title: Expression and significance of molecular biomarkers in esophageal carcinoma in different nationalities patients in Xinjiang.
Author: Zhang, L|Sun, J|Zhang, J Q|Yang, M|Bai, G|Ma, X L
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Journal: J Mol Med (Berl). 2014 Nov;92(11):1209-23.
Title: ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways.
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Journal: Int J Radiat Oncol Biol Phys. 2014 Sep 1;90(1):190-6.
Title: Preoperative chemoradiation therapy in combination with panitumumab for patients with resectable esophageal cancer: the PACT study.
Author: Kordes, Sil|van Berge Henegouwen, Mark I|Hulshof, Maarten C|Bergman, Jacques J G H M|van der Vliet, Hans J|Kapiteijn, Ellen|van Laarhoven, Hanneke W M|Richel, Dick J|Klinkenbijl, Jean H G|Meijer, Sybren L|Wilmink, Johanna W
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Journal: J Pharmacol Sci. 2014;126(1):77-83.
Title: Resistance to cetuximab in EGFR-overexpressing esophageal squamous cell carcinoma xenografts due to FGFR2 amplification and overexpression.
Author: Zhang, Yi|Pan, Tiecheng|Zhong, Xiaoxuan|Cheng, Cai
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Journal: Expert Opin Ther Targets. 2014 Dec;18(12):1421-6.
Title: The potential for targeting HER2 therapeutically in esophageal cancer - a grasp at straws?
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Journal: Int J Clin Exp Pathol. 2014 Oct 15;7(11):7663-71. eCollection 2014.
Title: Aquaporin-8 mediates human esophageal cancer Eca-109 cell migration via the EGFR-Erk1/2 pathway.
Author: Chang, Heng|Shi, Yong-Hua|Talaf, Tuo-Kan|Lin, Chen
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Journal: Mol Med Rep. 2015 Feb;11(2):961-7.
Title: A disintegrin and metalloproteinase 17 mRNA and protein expression in esophageal squamous cell carcinoma, as well as its clinicopathological factors and prognosis.
Author: Liu, Hong-Bin|Yang, Qi-Chang|Shen, Yi|Zhu, Yan|Zhang, Xiao-Juan|Chen, Hao
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Journal: Cancer Discov. 2015 Jan;5(1):OF4.
Title: Gefitinib extends survival in some esophageal cancers.
Author:
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Journal: Eur J Cancer. 2015 Mar;51(5):569-76.
Title: Lapatinib versus lapatinib plus capecitabine as second-line treatment in human epidermal growth factor receptor 2-amplified metastatic gastro-oesophageal cancer: a randomised phase II trial of the Arbeitsgemeinschaft Internistische Onkologie.
Author: Lorenzen, Sylvie|Riera Knorrenschild, Jorge|Haag, Georg-Martin|Pohl, Michael|Thuss-Patience, Peter|Bassermann, Florian|Helbig, Ulrike|Weissinger, Florian|Schnoy, Elisabeth|Becker, Klaus|Stocker, Gertraud|Ruschoff, Josef|Eisenmenger, Andreas|Karapanagiotou
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Journal: Clin Cancer Res. 2015 Jun 1;21(11):2580-90.
Title: The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer.
Author: Song, Shumei|Honjo, Soichiro|Jin, Jiankang|Chang, Shih-Shin|Scott, Ailing W|Chen, Qiongrong|Kalhor, Neda|Correa, Arlene M|Hofstetter, Wayne L|Albarracin, Constance T|Wu, Tsung-Teh|Johnson, Randy L|Hung, Mien-Chie|Ajani, Jaffer A
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Journal: Clin Cancer Res. 2015 Jun 1;21(11):2580-90.
Title: The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer.
Author: Song, Shumei|Honjo, Soichiro|Jin, Jiankang|Chang, Shih-Shin|Scott, Ailing W|Chen, Qiongrong|Kalhor, Neda|Correa, Arlene M|Hofstetter, Wayne L|Albarracin, Constance T|Wu, Tsung-Teh|Johnson, Randy L|Hung, Mien-Chie|Ajani, Jaffer A
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Journal: Onco Targets Ther. 2015 Feb 25;8:509-18.
Title: Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair.
Author: Liu, Hai|Yang, Weifang|Gao, Huaping|Jiang, Tingting|Gu, Bengxin|Dong, Qinghua|Xu, Wenhong|Wu, Shixiu|Sun, Xiaonan
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Journal: Med Oncol. 2015 Apr;32(4):124.
Title: Galectin-3 knockdown increases gefitinib sensitivity to the inhibition of EGFR endocytosis in gefitinib-insensitive esophageal squamous cancer cells.
Author: Cui, Guanghui|Cui, Mingwei|Li, Yuhang|Liang, Youguang|Li, Weihao|Guo, Haizhou|Zhao, Song
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Journal: PLoS One. 2015 Mar 31;10(3):e0121872.
Title: Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers.
Author: Dodbiba, Lorin|Teichman, Jennifer|Fleet, Andrew|Thai, Henry|Starmans, Maud H W|Navab, Roya|Chen, Zhuo|Girgis, Hala|Eng, Lawson|Espin-Garcia, Osvaldo|Shen, Xiaowei|Bandarchi, Bizhan|Schwock, Joerg|Tsao, Ming-Sound|El-Zimaity, Hala|Der, Sandy D|Xu, Wei|Bris
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Journal: Tumour Biol. 2015 Dec;36(12):9277-83.
Title: The relationship between the expression of VEGF, EGFR, and HER-2 mRNA in esophageal squamous cell carcinoma (ESCC) and clinicopathological features of different ethnic groups in Xinjiang.
Author: Zhang, Li|Wang, Yuling|Bai, Ge|Zhang, Jianqing|Yang, Mei|Ma, Xiaoli
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Journal: Oncotarget. 2015 Jul 30;6(21):18674-82.
Title: High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis.
Author: Wang, Chun-yu|Deng, Jia-ying|Cai, Xu-wei|Fu, Xiao-long|Li, Yuan|Zhou, Xiao-yan|Wu, Xiang-hua|Hu, Xi-chun|Fan, Min|Xiang, Jia-qing|Zhang, Ya-wei|Chen, Hai-quan|Perez, Rolando|Jiang, Guo-liang|Zhao, Kuai-le
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Journal: Vaccines (Basel). 2015 Jul 6;3(3):519-43.
Title: Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC).
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Journal: Oncotarget. 2015 Nov 10;6(35):38429-39.
Title: Concurrent radiotherapy with gefitinib in elderly patients with esophageal squamous cell carcinoma: Preliminary results of a phase II study.
Author: Xu, Yaping|Zheng, Yuanda|Sun, Xiaojiang|Yu, Xinmin|Gu, Jialei|Wu, Wei|Zhang, Gu|Hu, Jinlin|Sun, Wenyong|Mao, Weimin
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Journal: Med Sci Monit. 2015 Oct 12;21:3068-76.
Title: MTHFR C677T Polymorphism is Associated with Tumor Response to Preoperative Chemoradiotherapy: A Result Based on Previous Reports.
Author: Zhao, Yue|Li, Xingde|Kong, Xiangjun
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Journal: Biomed Opt Express. 2015 Sep 1;6(10):3714-23.
Title: In vivo multiplexed molecular imaging of esophageal cancer via spectral endoscopy of topically applied SERS nanoparticles.
Author: Wang, Yu Winston|Kang, Soyoung|Khan, Altaz|Bao, Philip Q|Liu, Jonathan T C
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Journal: Genet Mol Res. 2015 Dec 14;14(4):16819-26.
Title: Expression and prognostic influence of NF-kappaB and EGFR in esophageal cancer.
Author: Zhang, Y Q|Zhang, J J|Song, H J|Li, D W
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Journal: Oncol Lett. 2015 Dec;10(6):3696-3704. Epub 2015 Sep 25.
Title: Characterization of the expression and clinical features of epidermal growth factor receptor and vascular endothelial growth factor receptor-2 in esophageal carcinoma.
Author: Niyaz, Madiniyat|Anwer, Jurat|Liu, Hui|Zhang, Liwei|Shayhedin, Ilyar|Awut, Idiris
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Journal: Am J Cancer Res. 2015 Nov 15;5(12):3588-99. eCollection 2015.
Title: Preclinical evaluation of afatinib (BIBW2992) in esophageal squamous cell carcinoma (ESCC).
Author: Wong, Chi Hang|Ma, Brigette Buig Yue|Hui, Connie Wun Chun|Tao, Qian|Chan, Anthony Tak Cheung
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Journal: Zhonghua Yi Xue Za Zhi. 2015 Dec 15;95(47):3839-42.
Title: [Clinical implications of the concentration and EGFR/KRAS mutations of plasma cell free DNA of patients with lung cancer and esophageal cancer].
Author: Zhang, Ruixiang|Li, Yin|Chen, Yawei|Liu, Xianben|Wang, Zongfei|Sun, Haibo|Zheng, Yan|Ding, Zhidan|Lan, Ling|Li, Mingzhen|Qin, Jianjun|Chen, Xiankai
PMID: 27337801
Journal: Clin Transl Oncol. 2016 Jun;18(6):592-8.
Title: The relation of EGFR expression by immunohistochemical staining and clinical response of combination treatment of nimotuzumab and chemotherapy in esophageal squamous cell carcinoma.
Author: Jia, J|Cui, Y|Lu, M|Wang, X|Li, Jie|Li, Jian|Li, Y|Zhang, X|Gao, J|Zhou, J|Lu, Z|Gong, J|Yu, J|Sun, Z|Liu, C|Shen, L|Zhang, X
PMID: 26459251
Journal: J Cell Commun Signal. 2016 Mar;10(1):41-7.
Title: Subcellular localization of EGFR in esophageal carcinoma cell lines.
Author: Spohn, Lucas|Fichter, Christiane|Werner, Martin|Lassmann, Silke
PMID: 26582583
Journal: Onco Targets Ther. 2015 Dec 30;9:117-22.
Title: High-dose nimotuzumab improves the survival rate of esophageal cancer patients who underwent radiotherapy.
Author: Wang, Chunyu|Fu, Xiaolong|Cai, Xuwei|Wu, Xianghua|Hu, Xichun|Fan, Min|Xiang, Jiaqing|Zhang, Yawei|Chen, Haiquan|Jiang, Guoliang|Zhao, Kuaile
PMID: 26766917
Journal: Asian Pac J Trop Med. 2016 Jan;9(1):86-90.
Title: Effect of recombinant human endostatin onradiotherapy for esophagus cancer.
Author: Liu, Gao-Feng|Chang, Hui|Li, Bao-Tian|Zhang, Yong|Li, Dan-Dan|Liu, Yan|Yang, Yang
PMID: 26851794
Journal: Int J Cancer. 2016 Jun 15;138(12):2940-51.
Title: DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
Author: Ng, Hoi Yan|Ko, Josephine Mun-Yee|Yu, Valen Zhuoyou|Ip, Joseph Chok Yan|Dai, Wei|Cal, Santiago|Lung, Maria Li
PMID: 26856390
Journal: Gastroenterology. 2016 May;150(5):1171-1182.
Title: Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.
Author: Sawada, Genta|Niida, Atsushi|Uchi, Ryutaro|Hirata, Hidenari|Shimamura, Teppei|Suzuki, Yutaka|Shiraishi, Yuichi|Chiba, Kenichi|Imoto, Seiya|Takahashi, Yusuke|Iwaya, Takeshi|Sudo, Tomoya|Hayashi, Tomoatsu|Takai, Hiroki|Kawasaki, Yoshihiro|Matsukawa, Takashi
PMID: 26873401
Journal: Oncol Lett. 2016 Feb;11(2):973-978. Epub 2015 Dec 2.
Title: Study on chemotherapeutic sensitizing effect of nimotuzumab on different human esophageal squamous carcinoma cells.
Author: Yang, Xiaoyu|Ji, Yinghua|Kang, Xiaochun|Chen, Meiling|Kou, Weizheng|Jin, Cailing|Lu, Ping
PMID: 26893678
Journal: Expert Rev Gastroenterol Hepatol. 2016;10(5):595-604.
Title: Targeted therapy in esophageal cancer.
Author: Zhang, Lei|Ma, Jiaojiao|Han, Yu|Liu, Jinqiang|Zhou, Wei|Hong, Liu|Fan, Daiming
PMID: 26895097
Journal: Genet Mol Res. 2016 Jun 24;15(2).
Title: Effect of SNX-2112 on proliferation of esophageal cancer cells via regulation of excision repair cross-complementing 1, epidermal growth factor receptor, and p53 expression.
Author: Li, C Y|Ren, Y J|Li, Y D
PMID: 27420968
Journal: J Thorac Dis. 2016 Jul;8(7):1753-63.
Title: Assessment of epidermal growth factor receptor mutation/copy number and K-ras mutation in esophageal cancer.
Author: Guo, Kang|Wang, Wu-Ping|Jiang, Tao|Wang, Ju-Zheng|Chen, Zhao|Li, Yong|Zhou, Yong-An|Li, Xiao-Fei|Lu, Qiang|Zhang, Lan-Jun
PMID: 27499966
Journal: Zhonghua Zhong Liu Za Zhi. 2016 Oct 23;38(10):732-738.
Title: [Effects and its mechanism of Nimotuzumab on radiosensitivity of esophageal carcinoma ECA-109 and TE-13 cell lines].
Author: Wang, J|Wang, W|Guo, Y|Jing, S W|Shang, K|Miao, M C|Wang, J|Wu, Y J|Liu, L N|Yu, J M
PMID: 27784455
Journal: Am J Transl Res. 2016 Dec 15;8(12):5729-5740. eCollection 2016.
Title: Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers.
Author: Wu, Jianzhong|Li, Shuchun|Ma, Rong|Sharma, Ashok|Bai, Shan|Dun, Boying|Cao, Haixia|Jing, Changwen|She, Jinxiong|Feng, Jifeng
PMID: 28078044
Journal: Am J Clin Oncol. 2017 Aug;40(4):393-398.
Title: Induction Therapy for Locally Advanced, Resectable Esophagogastric Cancer: A Phase I Trial of Vandetanib (ZD6474), Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiotherapy Followed by Resection.
Author: Boland, Patrick M|Meyer, Joshua E|Berger, Adam C|Cohen, Steven J|Neuman, Tzahi|Cooper, Harry S|Olszanski, Anthony J|Davey, Monica|Cheng, Jonathan D|Lebenthal, Abraham|Burtness, Barbara A|Scott, Walter J|Astsaturov, Igor A
PMID: 26986978
Journal: J Cell Biochem. 2017 Sep;118(9):2625-2634.
Title: Up-Regulation of MicroRNA-133a Inhibits the MEK/ERK Signaling Pathway to Promote Cell Apoptosis and Enhance Radio-Sensitivity by Targeting EGFR in Esophageal Cancer In Vivo and In Vitro.
Author: Yang, Qing-Shan|Jiang, Li-Peng|He, Chun-Yan|Tong, Yu-Na|Liu, Yuan-Yuan
PMID: 27933650
Journal: Oncotarget. 2017 Jan 31;8(5):8536-8549.
Title: The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKalpha/mTOR pathway in vitro and in vivo.
Author: Fujihara, Shintaro|Morishita, Asahiro|Ogawa, Kana|Tadokoro, Tomoko|Chiyo, Taiga|Kato, Kiyohito|Kobara, Hideki|Mori, Hirohito|Iwama, Hisakazu|Masaki, Tsutomu
PMID: 28052030
Journal: Curr Pharm Des. 2017;23(16):2314-2320.
Title: The Role of Epidermal Growth Factor Receptor in the Management of Gastrointestinal Carcinomas: Present Status and Future Perspectives.
Author: Mahmood, Malik Quasir|Shukla, Shakti Dhar|Dua, Kamal|Shastri, Madhur D
PMID: 28120720
Journal: Gastroenterology. 2017 Jul;153(1):63-76.e14.
Title: Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
Author: Ebbing, Eva A|Steins, Anne|Fessler, Evelyn|Stathi, Phylicia|Lesterhuis, Willem Joost|Krishnadath, Kausilia K|Vermeulen, Louis|Medema, Jan Paul|Bijlsma, Maarten F|van Laarhoven, Hanneke W M
PMID: 28286209
Journal: Pharmacol Res. 2017 May;119:479-489.
Title: Single molecule force spectroscopy for in-situ probing oridonin inhibited ROS-mediated EGF-EGFR interactions in living KYSE-150 cells.
Author: Pi, Jiang|Jin, Hua|Jiang, Jinhuan|Yang, Fen|Cai, Huaihong|Yang, Peihui|Cai, Jiye|Chen, Zheng W
PMID: 28411855
Journal: Arch Iran Med. 2017 Apr;20(4):240-245.
Title: EGFR Expression in Patients with Esophageal Squamous Cell Carcinoma and its Association with Pathologic Response to Preoperative Chemoradiotherapy: A Study in Northeastern Iran.
Author: Anvari, Kazem|Sima, Hamid R|Seilanian Toussi, Mehdi|Anvari, Azam|Shahidsales, Soodabeh|Memar, Bahram|Aledavoud, Seyed Amir|Forghani, Mohammad N|Abdollahi, Abbas|Ghaffarzadegan, Kamran
PMID: 28412829
Journal: Oncotarget. 2017 May 2;8(18):29846-29856.
Title: Tyrosine kinase inhibitor induced growth factor receptor upregulation enhances the efficacy of near-infrared targeted photodynamic therapy in esophageal adenocarcinoma cell lines.
Author: Hartmans, Elmire|Linssen, Matthijs D|Sikkens, Claire|Levens, Afra|Witjes, Max J H|van Dam, Gooitzen M|Nagengast, Wouter B
PMID: 28415738
Journal: Oncol Rep. 2017 Jun;37(6):3329-3340.
Title: A ligand-based and enediyne-energized bispecific fusion protein targeting epidermal growth factor receptor and insulin-like growth factor-1 receptor shows potent antitumor efficacy against esophageal cancer.
Author: Cao, Hai-Ying|Guo, Xiao-Fang|Zhu, Xiao-Fei|Li, Sai-Sai|Zhen, Yong-Su
PMID: 28498434
Journal: J Clin Oncol. 2017 Jul 10;35(20):2279-2287.
Title: Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer.
Author: Petty, Russell D|Dahle-Smith, Asa|Stevenson, David A J|Osborne, Aileen|Massie, Doreen|Clark, Caroline|Murray, Graeme I|Dutton, Susan J|Roberts, Corran|Chong, Irene Y|Mansoor, Wasat|Thompson, Joyce|Harrison, Mark|Chatterjee, Anirban|Falk, Stephen J|Elyan,
PMID: 28537764
Journal: JAMA Oncol. 2017 Jul 6.
Title: Effect of the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation Therapy for Patients With Esophageal Cancer: The NRG Oncology RTOG 0436 Phase 3 Randomized Clinical Trial.
Author: Suntharalingam, Mohan|Winter, Kathryn|Ilson, David|Dicker, Adam P|Kachnic, Lisa|Konski, Andre|Chakravarthy, A Bapsi|Anker, Christopher J|Thakrar, Harish|Horiba, Naomi|Dubey, Ajay|Greenberger, Joel S|Raben, Adam|Giguere, Jeffrey|Roof, Kevin|Videtic, Gregor
PMID: 28687830
Journal: Mod Pathol. 2017 Jul 21.
Title: Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia.
Author: Singhi, Aatur D|Arnold, Christina A|Lam-Himlin, Dora M|Nikiforova, Marina N|Voltaggio, Lysandra|Canto, Marcia I|McGrath, Kevin M|Montgomery, Elizabeth A
PMID: 28731047
Journal: Photodiagnosis Photodyn Ther. 2017 Aug 12. pii: S1572-1000(17)30265-X.
Title: Influence and mechanism of 5-aminolevulinic acid-photodynamic therapy on the metastasis of esophageal carcinoma.
Author: Zhang, Xiaona|Cai, Longmei|He, Jingcai|Li, Xiaoyan|Li, Libo|Chen, Xiaohua|Lan, Ping
PMID: 28811223
Journal: Oncotarget. 2017 Apr 19;8(31):50832-50844.
Title: Anti-tumor efficacy of theliatinib in esophageal cancer patient-derived xenografts models with epidermal growth factor receptor (EGFR) overexpression and gene amplification.
Author: Ren, Yongxin|Zheng, Jianming|Fan, Shiming|Wang, Linfang|Cheng, Min|Shi, Dongxia|Zhang, Wei|Tang, Renxiang|Yu, Ying|Jiao, Longxian|Ni, Jun|Yang, Haibin|Cai, Huaqing|Yin, Fang|Chen, Yunxin|Zhou, Feng|Zhang, Weihan|Qing, Weiguo|Su, Weiguo
PMID: 28881608
Journal: Drug Deliv. 2017 Nov;24(1):1549-1564.
Title: GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways.
Author: Pi, Jiang|Jiang, Jinhuan|Cai, Huaihong|Yang, Fen|Jin, Hua|Yang, Peihui|Cai, Jiye|Chen, Zheng W
PMID: 29019267
Journal: Klin Onkol. 2017 Winter;30(Supplementum3):50-54.
Title: [Checkpoint Inhibitors in the Treatment of Upper Gastrointestinal Tract Tumors].
Author: Obermannova, R
PMID: 29239193
Journal: Curr Cancer Drug Targets. 2018;18(5):430-441.
Title: The Role of Target Therapy in the Treatment of Gastrointestinal Noncolorectal Cancers: Clinical Impact and Cost Consideration.
Author: Berretta, Massimiliano|Romano, Carmela|Di Francia, Raffaele|De Diviitis, Chiara|Canzonieri, Vincenzo|Caraglia, Michele|Facchini, Gaetano|Nasti, Guglielmo
PMID: 28183250
Journal: Oncogene. 2018 Feb 15;37(7):935-943.
Title: Neuropilin-1 contributes to esophageal squamous cancer progression via promoting P65-dependent cell proliferation.
Author: Shi, F|Shang, L|Yang, L-Y|Jiang, Y-Y|Wang, X-M|Hao, J-J|Zhang, Y|Huang, D-K|Cai, Y|Xu, X|Zhan, Q-M|Jia, X-M|Cao, Y|Wang, M-R
PMID: 29059172
Journal: Ann Thorac Surg. 2018 Feb;105(2):363-370.
Title: HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells.
Author: Goltsov, Alexei A|Fang, Bingliang|Pandita, Tej K|Maru, Dipen M|Swisher, Stephen G|Hofstetter, Wayne L
PMID: 29223420
Journal: J Cancer. 2018 Jan 1;9(1):32-40.
Title: Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms in vitro and in vivo.
Author: Tang, Jian-Cai|Zhao, Jia|Long, Feng|Chen, Jian-Ye|Mu, Bo|Jiang, Zhen|Ren, Yonggan|Yang, Jian
PMID: 29290767
Journal: Mol Cancer. 2018 Feb 19;17(1):54.
Title: Expression, regulation and targeting of receptor tyrosine kinases in esophageal squamous cell carcinoma.
Author: Kashyap, Manoj Kumar|Abdel-Rahman, Omar
PMID: 29455652
Journal: J Cancer Res Ther. 2018 Jan;14(1):103-105.
Title: Detection of epidermal growth factor receptor mutation in the peripheral blood of patients with esophageal carcinoma to guide epidermal growth factor receptor-tyrosine kinase inhibitor treatment.
Author: Xu, Yingjun|Xie, Zhihui|Lu, Hong
PMID: 29516969
Journal: Mol Cancer Ther. 2018 Jun;17(6):1229-1239.
Title: Itraconazole-Induced Inhibition on Human Esophageal Cancer Cell Growth Requires AMPK Activation.
Author: Chen, Min-Bin|Liu, Yuan-Yuan|Xing, Zhao-Yu|Zhang, Zhi-Qing|Jiang, Qin|Lu, Pei-Hua|Cao, Cong
PMID: 29592879
Journal: Ann Oncol. 2018 Jun 1;29(6):1343-1344.
Title: Is there a future for EGFR targeted agents in esophageal cancer?
Author: Ilson, D H
PMID: 29668836
Journal: Mol Carcinog. 2018 Jul 23.
Title: Quercetin-3-methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways.
Author: Zhao, Simin|Jiang, Yanan|Zhao, Jimin|Li, Honglin|Yin, Xueshan|Wang, Yanhong|Xie, Yifei|Chen, Xinhuan|Lu, Jing|Dong, Ziming|Liu, Kangdong
PMID: 30035335
Journal: Cell Mol Biol Lett. 2018 Sep 3;23:42.
Title: WNT and NOTCH signaling pathways as activators for epidermal growth factor receptor in esophageal squamous cell carcinoma.
Author: Abbaszadegan, Mohammad Reza|Riahi, Anali|Forghanifard, Mohammad Mahdi|Moghbeli, Meysam
PMID: 30202417
Journal: Am Soc Clin Oncol Educ Book. 2018 May 23;(38):249-261.
Title: What Will We Expect From Novel Therapies to Esophageal and Gastric Malignancies?
Author: De Mello, Ramon Andrade|Castelo-Branco, Luis|Castelo-Branco, Pedro|Pozza, Daniel Humberto|Vermeulen, Louis|Palacio, Sofia|Salzberg, Matthew|Lockhart, A Craig
PMID: 30231398
Journal: J Biomater Appl. 2018 Nov 2:885328218809019.
Title: Enhancement of radiotherapeutic efficacy for esophageal cancer by paclitaxel-loaded red blood cell membrane nanoparticles modified by the recombinant protein anti-EGFR-iRGD.
Author: Ren, Wei|Sha, Huizi|Yan, Jing|Wu, Puyuan|Yang, Ju|Li, Rutian|Zhang, Hang|Yu, Lixia|Qian, Hanqing|Liu, Baorui
PMID: 30388386