Literatures

Primary Site >> Colorectal Cancer

Gene >> EGFR

1.
Journal:	Cancer Res. 1985 Sep;45(9):4433-8.
Title:	Amplification and elevated expression of c-myc in a chemically induced mouse colon tumor.
Author:	Yander, G\|Halsey, H\|Kenna, M\|Augenlicht, L H
PMID:	4028026

2.
Journal:	Cancer Res. 1987 Sep 1;47(17):4590-4.
Title:	Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model.
Author:	Coffey, R J Jr\|Goustin, A S\|Soderquist, A M\|Shipley, G D\|Wolfshohl, J\|Carpenter, G\|Moses, H L
PMID:	2887281

3.
Journal:	J Surg Res. 1989 Nov;47(5):418-22.
Title:	Ras gene activation and epidermal growth factor receptor expression in human colon cancer.
Author:	Ravikumar, T S\|Wolf, B\|Cocchiaro, C\|D'Emilia, J\|Steele, G Jr
PMID:	2682005

4.
Journal:	Virchows Arch B Cell Pathol Incl Mol Pathol. 1990;59(3):173-8.
Title:	Expression of several growth factors and their receptor genes in human colon carcinomas.
Author:	Ito, M\|Yoshida, K\|Kyo, E\|Ayhan, A\|Nakayama, H\|Yasui, W\|Ito, H\|Tahara, E
PMID:	1980764

5.
Journal:	Jpn J Exp Med. 1990 Dec;60(6):343-9.
Title:	erbB-2 gene expression in colorectal cancer.
Author:	Tsioulias, G J\|Muto, T\|Morioka, Y\|Yamamoto, T\|Mori, S
PMID:	1982887

6.
Journal:	Virchows Arch A Pathol Anat Histopathol. 1990;416(4):343-9.
Title:	Expression of epidermal growth factor receptor in normal colorectal mucosa, adenoma, and carcinoma.
Author:	Koretz, K\|Schlag, P\|Moller, P
PMID:	2106751

7.
Journal:	J Cancer Res Clin Oncol. 1990;116(2):121-31.
Title:	Growth factors and oncogenes in human gastrointestinal carcinomas.
Author:	Tahara, E
PMID:	2157713

8.
Journal:	Anticancer Res. 1990 May-Jun;10(3):605-11.
Title:	Epidermal growth factor receptors in colorectal carcinoma.
Author:	Moorghen, M\|Ince, P\|Finney, K J\|Watson, A J\|Harris, A L
PMID:	2195985

9.
Journal:	J Cell Biochem. 1990 Oct;44(2):69-79.
Title:	Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha.
Author:	Rodeck, U\|Williams, N\|Murthy, U\|Herlyn, M
PMID:	2250044

10.
Journal:	J Clin Invest. 1990 Jul;86(1):356-62.
Title:	Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium.
Author:	Markowitz, S D\|Molkentin, K\|Gerbic, C\|Jackson, J\|Stellato, T\|Willson, J K
PMID:	2365825

11.
Journal:	Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7792-6.
Title:	Differential expression of epidermal growth factor-related proteins in human colorectal tumors.
Author:	Ciardiello, F\|Kim, N\|Saeki, T\|Dono, R\|Persico, M G\|Plowman, G D\|Garrigues, J\|Radke, S\|Todaro, G J\|Salomon, D S
PMID:	1715580

12.
Journal:	Nihon Shokakibyo Gakkai Zasshi. 1991 May;88(5):1177-83.
Title:	[Immunohistochemical study on the expression of epidermal growth factor receptor (EGFR) in human colorectal carcinomas].
Author:	Takemura, K\|Obara, T\|Okano, S\|Yokota, K\|Ura, H\|Saitoh, Y\|Koike, Y\|Okamura, K\|Namiki, M
PMID:	1880949

13.
Journal:	J Surg Oncol. 1991 Nov;48(3):183-7.
Title:	Receptors for epidermal growth factor and steroid hormones in primary colorectal tumors.
Author:	Scambia, G\|Panici, P B\|Bellantone, R\|Doglietto, G B\|Sofo, L\|Ferrandina, G\|Ratto, C\|Bossola, M\|Crucitti, F\|Spagnolo, L C
PMID:	1943115

14.
Journal:	Genes Chromosomes Cancer. 1991 Jan;3(1):48-54.
Title:	Extrachromosomal amplification of the epidermal growth factor receptor gene in a human colon carcinoma cell line.
Author:	Dolf, G\|Meyn, R E\|Curley, D\|Prather, N\|Story, M D\|Boman, B M\|Siciliano, M J\|Hewitt, R R
PMID:	2069908

15.
Journal:	Mol Cell Biol. 1991 Aug;11(8):4005-14.
Title:	The proliferative and morphologic responses of a colon carcinoma cell line (LIM 1215) require the production of two autocrine factors.
Author:	Sizeland, A M\|Burgess, A W
PMID:	2072905

16.
Journal:	Surg Oncol. 1992 Feb;1(1):97-105.
Title:	Correlation of epidermal growth factor receptor and c-erbB2 oncogene product to known prognostic indicators of colorectal cancer.
Author:	Kluftinger, A M\|Robinson, B W\|Quenville, N F\|Finley, R J\|Davis, N L
PMID:	1285215

17.
Journal:	Growth Factors. 1992;7(3):195-205.
Title:	Colorectum cell-derived growth factor (CRDGF) is homologous to amphiregulin, a member of the epidermal growth factor family.
Author:	Culouscou, J M\|Remacle-Bonnet, M\|Carlton, G W\|Plowman, G D\|Shoyab, M
PMID:	1333777

18.
Journal:	Gan To Kagaku Ryoho. 1992 Jan;19(1):34-9.
Title:	[Expression of c-erbB-2 protein and vessel invasion in colorectal cancer].
Author:	Yamaguchi, S\|Ohki, S\|Jo, T\|Imai, S\|Matsuo, K\|Hamahata, Y\|Fukano, M\|Tokito, S\|Hasegawa, S\|Masui, H
PMID:	1346087

19.
Journal:	Br J Cancer. 1992 Oct;66(4):712-6.
Title:	Interleukin-4 receptor and epidermal growth factor receptor expression in colorectal cancer.
Author:	Kaklamanis, L\|Gatter, K C\|Mortensen, N\|Harris, A L
PMID:	1419612

20.
Journal:	Cell Growth Differ. 1992 Jun;3(6):347-54.
Title:	Differential regulation of transforming growth factor alpha autoinduction in a nontransformed and transformed epithelial cell.
Author:	Coffey, R J Jr\|Graves-Deal, R\|Dempsey, P J\|Whitehead, R H\|Pittelkow, M R
PMID:	1419897

21.
Journal:	J Surg Oncol. 1992 Nov;51(3):147-52.
Title:	Prognostic markers of colorectal cancer: an evaluation of DNA content, epidermal growth factor receptor, and Ki-67.
Author:	Hemming, A W\|Davis, N L\|Kluftinger, A\|Robinson, B\|Quenville, N F\|Liseman, B\|LeRiche, J
PMID:	1434639

22.
Journal:	Mol Biol (Mosk). 1992 Sep-Oct;26(5):1134-47.
Title:	[Complex characteristics of the alterations of oncogenes HER-2/ERBB-2, HER-1/ERBB-1, HRAS-1, C-MYC and antioncogenes p53, RB1, as well as deletions of loci of chromosome 17 in colon carcinoma].
Author:	Kniazev, P G\|Imianitov, E N\|Chernitsa, O I\|Nikiforova, I F\|Babenko, V I\|Bruderliain, S\|Plutalo, O V\|Kuz'min, A I\|Kaboev, O K\|Berlin, Iu A
PMID:	1470178

23.
Journal:	Gastroenterology. 1992 Feb;102(2):474-85.
Title:	Autonomous proliferation of colon cancer cells that coexpress transforming growth factor alpha and its receptor. Variable effects of receptor-blocking antibody.
Author:	Karnes, W E Jr\|Walsh, J H\|Wu, S V\|Kim, R S\|Martin, M G\|Wong, H C\|Mendelsohn, J\|Park, J G\|Cuttitta, F
PMID:	1732118

24.
Journal:	Br J Cancer. 1992 Feb;65(2):189-92.
Title:	Epidermal growth factor receptor levels are lower in carcinomatous than in normal colorectal tissue.
Author:	Koenders, P G\|Peters, W H\|Wobbes, T\|Beex, L V\|Nagengast, F M\|Benraad, T J
PMID:	1739615

25.
Journal:	Oncogene. 1992 Jan;7(1):181-5.
Title:	Overexpression of c-met proto-oncogene but not epidermal growth factor receptor or c-erbB-2 in primary human colorectal carcinomas.
Author:	Liu, C\|Park, M\|Tsao, M S
PMID:	1741162

26.
Journal:	J Natl Cancer Inst. 1993 Sep 1;85(17):1419-24.
Title:	Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells.
Author:	Pantel, K\|Schlimok, G\|Braun, S\|Kutter, D\|Lindemann, F\|Schaller, G\|Funke, I\|Izbicki, J R\|Riethmuller, G
PMID:	7688814

27.
Journal:	J Surg Oncol. 1993 Dec;54(4):246-51.
Title:	Study of c-erbB-2 protein and epidermal growth factor receptor expression and DNA ploidy pattern in colorectal carcinoma.
Author:	Nakae, S\|Shimada, E\|Urakawa, T
PMID:	7902886

28.
Journal:	Nihon Shokakibyo Gakkai Zasshi. 1993 Nov;90(11):2889-94.
Title:	[Immunohistochemical study of the coexpression of epidermal growth factor receptor (EGFR) and c-erbB-2 protein in colorectal cancer].
Author:	Shimada, E\|Urakawa, T\|Ueda, T
PMID:	7903710

29.
Journal:	Cancer. 1993 Apr 15;71(8):2454-60.
Title:	The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer.
Author:	Mayer, A\|Takimoto, M\|Fritz, E\|Schellander, G\|Kofler, K\|Ludwig, H
PMID:	8095852

30.
Journal:	Clin Investig. 1993 Nov;71(11):903-7.
Title:	Epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor content in normal and carcinomatous gastric and colonic tissue.
Author:	Borlinghaus, P\|Wieser, S\|Lamerz, R
PMID:	8312682

31.
Journal:	Cancer Res. 1993 Mar 1;53(5):937-43.
Title:	A rapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas.
Author:	Radinsky, R\|Bucana, C D\|Ellis, L M\|Sanchez, R\|Cleary, K R\|Brigati, D J\|Fidler, I J
PMID:	8439966

32.
Journal:	Cancer Res. 1993 Apr 1;53(7):1630-6.
Title:	Transforming growth factor-alpha production and autoinduction in a colorectal carcinoma cell line (DiFi) with an amplified epidermal growth factor receptor gene.
Author:	Untawale, S\|Zorbas, M A\|Hodgson, C P\|Coffey, R J\|Gallick, G E\|North, S M\|Wildrick, D M\|Olive, M\|Blick, M\|Yeoman, L C
PMID:	8453634

33.
Journal:	Exp Cell Res. 1993 May;206(1):49-57.
Title:	Growth control in a human colon carcinoma cell line mediated by cell-associated transforming growth factor-alpha (TGF alpha).
Author:	Zorbas, M A\|Yeoman, L C
PMID:	8482359

34.
Journal:	Int J Cancer. 1993 May 8;54(2):189-93.
Title:	In situ evaluation of the relationship between epidermal-growth-factor-receptor status and tumor-cell proliferation in colon carcinomas.
Author:	Porschen, R\|Classen, S\|Kahle, Y\|Borchard, F
PMID:	8486422

35.
Journal:	Hokkaido Igaku Zasshi. 1993 Mar;68(2):166-75.
Title:	[Immunohistochemical studies on expression of epidermal growth factor receptor (EGFR) and proliferative activity in human colorectal cancers].
Author:	Koike, Y
PMID:	8509061

36.
Journal:	J Gastroenterol. 1994 Oct;29(5):616-20.
Title:	Serum levels of c-erbB-2 protein in digestive diseases.
Author:	Motoo, Y\|Sawabu, N\|Yamaguchi, Y\|Mouri, I\|Yamakawa, O\|Watanabe, H\|Ohta, H\|Okai, T\|Makino, H
PMID:	7528080

37.
Journal:	Curr Probl Cancer. 1994 Jul-Aug;18(4):189-247.
Title:	Esophageal cancer.
Author:	Coia, L R\|Sauter, E R
PMID:	7533069

38.
Journal:	Invasion Metastasis. 1994-1995;14(1-6):362-71.
Title:	Accelerated growth of human colon cancer cells in nude mice undergoing liver regeneration.
Author:	Gutman, M\|Singh, R K\|Price, J E\|Fan, D\|Fidler, I J
PMID:	7657529

39.
Journal:	Histopathology. 1994 Nov;25(5):455-61.
Title:	Cytoplasmic c-erbB-2 protein expression correlates with survival in Dukes' B colorectal carcinoma.
Author:	Kay, E W\|Mulcahy, H\|Walsh, C B\|Leader, M\|O'Donoghue, D
PMID:	7868086

40.
Journal:	Pathol Int. 1994 Feb;44(2):124-30.
Title:	Expression of EGF, EGF-receptor, p53, v-erb B and ras p21 in colorectal neoplasms by immunostaining paraffin-embedded tissues.
Author:	Hayashi, Y\|Widjono, Y W\|Ohta, K\|Hanioka, K\|Obayashi, C\|Itoh, K\|Imai, Y\|Itoh, H
PMID:	7912978

41.
Journal:	Digestion. 1994;55(2):103-7.
Title:	Demonstration of epidermal growth factor receptor in colorectal adenocarcinoma by enzyme immunoassay.
Author:	Messa, C\|Russo, F\|Notarnicola, M\|Di Leo, A
PMID:	8187972

42.
Journal:	Cancer. 1994 Feb 1;73(3 Suppl):884-9.
Title:	Indium-111-labeled anti-EGFr-425 scintigraphy in the detection of malignant gliomas.
Author:	Dadparvar, S\|Krishna, L\|Miyamoto, C\|Brady, L W\|Brown, S J\|Bender, H\|Slizofski, W J\|Eshleman, J\|Chevres, A\|Woo, D V
PMID:	8306274

43.
Journal:	Int J Oncol. 1994 Sep;5(3):445-51.
Title:	Expression of cripto-1 in human colorectal adenomas and carcinomas is related to the degree of dysplasia.
Author:	Saeki, T\|Salomon, D\|Gullick, W\|Mandai, K\|Yamagami, K\|Moriwaki, S\|Takashima, S\|Nishikawa, Y\|Tahara, E
PMID:	21559596

44.
Journal:	Int J Cancer. 1995 Sep 15;62(6):661-7.
Title:	Epidermal growth factor expression in human colon and colon carcinomas: anti-sense epidermal growth factor receptor RNA down-regulates the proliferation of human colon cancer cells.
Author:	Rajagopal, S\|Huang, S\|Moskal, T L\|Lee, B N\|el-Naggar, A K\|Chakrabarty, S
PMID:	7558411

45.
Journal:	J Clin Lab Anal. 1995;9(4):243-51.
Title:	PSA immunoreactivity detected in LNCaP cell medium, breast tumor cytosol, and female serum.
Author:	Wu, J T\|Zhang, P\|Astill, M E\|Wilson, L W\|Lyons, B W\|Wu, L L\|Stephenson, R
PMID:	7562242

46.
Journal:	Clin Exp Metastasis. 1995 May;13(3):191-5.
Title:	Expression of antisense epidermal growth factor receptor RNA downmodulates the malignant behavior of human colon cancer cells.
Author:	Chakrabarty, S\|Rajagopal, S\|Huang, S
PMID:	7750206

47.
Journal:	Eur J Surg Oncol. 1995 Jun;21(3):269-75.
Title:	Expression of epidermal growth factor receptor messenger RNA in human colorectal carcinomas assessed by non-radioactive in-situ hybridization.
Author:	Komuta, K\|Koji, T\|Izumi, S\|Matsumoto, T\|Kohara, N\|Motojima, K\|Kanematsu, T\|Nakane, P K
PMID:	7781795

48.
Journal:	J Cell Physiol. 1995 Feb;162(2):256-65.
Title:	Regulation of autocrine gastrin expression by the TGF alpha autocrine loop.
Author:	Howell, G M\|Ziober, B L\|Humphrey, L E\|Willson, J K\|Sun, L\|Lynch, M\|Brattain, M G
PMID:	7822434

49.
Journal:	Dig Dis Sci. 1995 Mar;40(3):485-94.
Title:	Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease.
Author:	Alexander, R J\|Panja, A\|Kaplan-Liss, E\|Mayer, L\|Raicht, R F
PMID:	7895532

50.
Journal:	Anticancer Res. 1995 Nov-Dec;15(6B):2889-94.
Title:	Expression of growth factors and their receptors in human early colorectal carcinomas: immunohistochemical study.
Author:	Shirai, H\|Ueno, E\|Osaki, M\|Tatebe, S\|Ito, H\|Kaibara, N
PMID:	8669884

51.
Journal:	Clin Cancer Res. 1995 Feb;1(2):161-7.
Title:	Cooperative antiproliferative effects of 8-chloro-cyclic AMP and 528 anti-epidermal growth factor receptor monoclonal antibody on human cancer cells.
Author:	Ciardiello, F\|Damiano, V\|Bianco, C\|di Isernia, G\|Ruggiero, A\|Caraglia, M\|Tagliaferri, P\|Baselga, J\|Mendelsohn, J\|Bianco, A R
PMID:	9815969

52.
Journal:	Cancer Lett. 1996 Jan 2;98(2):183-91.
Title:	p53 functional loss in a colon cancer cell line with two missense mutations (218leu and 248trp) on separate alleles.
Author:	Rand, A\|Glenn, K S\|Alvares, C P\|White, M B\|Thibodeau, S M\|Karnes, W E Jr
PMID:	8556707

53.
Journal:	J Cancer Res Clin Oncol. 1996;122(6):328-34.
Title:	Autocrine growth stimulation of SW403 colon carcinoma cell line is caused by transforming-growth-factor-alpha-mediated epidermal growth factor receptor activation.
Author:	Hirsch, T\|Eggstein, S\|Frank, S\|Farthmann, E\|von Specht, B U
PMID:	8642042

54.
Journal:	Dig Dis Sci. 1996 Jun;41(6):1069-75.
Title:	Raf-1 kinase, epidermal growth factor receptors, and mutant Ras proteins in colonic carcinomas.
Author:	Eggstein, S\|Manthey, G\|Hirsch, T\|Baas, F\|Specht, B U\|Farthmann, E H
PMID:	8654136

55.
Journal:	J Natl Cancer Inst. 1996 Dec 4;88(23):1770-6.
Title:	Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A.
Author:	Ciardiello, F\|Damiano, V\|Bianco, R\|Bianco, C\|Fontanini, G\|De Laurentiis, M\|De Placido, S\|Mendelsohn, J\|Bianco, A R\|Tortora, G
PMID:	8944008

56.
Journal:	Int J Oncol. 1996 Jun;8(6):1105-11.
Title:	Differential expression of platelet-derived endothelial cell growth factor (thymidine phosphorylase) in nonpolypoid and polypoid lesions of the colon.
Author:	Saeki, T\|Takashima, S\|Hosokawa, S\|Moriwaki, S\|Nagasako, K\|Masaki, T\|Salomon, D\|Ishitsuka, H
PMID:	21544470

57.
Journal:	Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):657-62.
Title:	Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells.
Author:	Coffey, R J\|Hawkey, C J\|Damstrup, L\|Graves-Deal, R\|Daniel, V C\|Dempsey, P J\|Chinery, R\|Kirkland, S C\|DuBois, R N\|Jetton, T L\|Morrow, J D
PMID:	9012840

58.
Journal:	J Med Chem. 1997 Feb 14;40(4):413-26.
Title:	Tyrosine kinase inhibitors. 6. Structure-activity relationships among N- and 3-substituted 2,2'-diselenobis(1H-indoles) for inhibition of protein tyrosine kinases and comparative in vitro and in vivo studies against selected sulfur congeners.
Author:	Showalter, H D\|Sercel, A D\|Leja, B M\|Wolfangel, C D\|Ambroso, L A\|Elliott, W L\|Fry, D W\|Kraker, A J\|Howard, C T\|Lu, G H\|Moore, C W\|Nelson, J M\|Roberts, B J\|Vincent, P W\|Denny, W A\|Thompson, A M
PMID:	9046331

59.
Journal:	J R Coll Surg Edinb. 1997 Apr;42(2):98-101.
Title:	Expression of growth factor receptors is not a prognostic indicator in young patients with colorectal cancer.
Author:	Langlois, N\|Walker, L G\|Smith, I\|Skinner, L\|Eremin, O\|Heys, S D
PMID:	9114679

60.
Journal:	Anticancer Res. 1997 May-Jun;17(3C):1925-31.
Title:	The epidermal growth factor receptor is involved in autocrine growth of human bladder carcinoma cell lines.
Author:	Ruck, A\|Paulie, S
PMID:	9216646

61.
Journal:	Cancer Res. 1997 Nov 1;57(21):4838-48.
Title:	Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase.
Author:	Moyer, J D\|Barbacci, E G\|Iwata, K K\|Arnold, L\|Boman, B\|Cunningham, A\|DiOrio, C\|Doty, J\|Morin, M J\|Moyer, M P\|Neveu, M\|Pollack, V A\|Pustilnik, L R\|Reynolds, M M\|Sloan, D\|Theleman, A\|Miller, P
PMID:	9354447

62.
Journal:	Oncogene. 1997 Nov 27;15(22):2705-16.
Title:	ErbB kinases and NDF signaling in human prostate cancer cells.
Author:	Grasso, A W\|Wen, D\|Miller, C M\|Rhim, J S\|Pretlow, T G\|Kung, H J
PMID:	9400997

63.
Journal:	Cancer Immunol Immunother. 1997 Nov-Dec;45(3-4):210-5.
Title:	Clinical experience with CD64-directed immunotherapy. An overview.
Author:	Curnow, R T
PMID:	9435876

64.
Journal:	Oncogene. 1997 Dec 18;15(25):3083-90.
Title:	Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential.
Author:	Mao, W\|Irby, R\|Coppola, D\|Fu, L\|Wloch, M\|Turner, J\|Yu, H\|Garcia, R\|Jove, R\|Yeatman, T J
PMID:	9444956

65.
Journal:	Semin Surg Oncol. 1998 Jan-Feb;14(1):3-12.
Title:	Molecular changes during the genesis of human gliomas.
Author:	Sehgal, A
PMID:	9407626

66.
Journal:	Oncol Rep. 1998 Jan-Feb;5(1):261-6.
Title:	Distinctive karyotypes and growth patterns in nude mice reveal cross-contamination in an established human cancer cell line.
Author:	Price, J E\|Wolf, J K\|Pathak, S
PMID:	9458333

67.
Journal:	J Cell Physiol. 1998 May;175(2):174-83.
Title:	Expression of TGFalpha autocrine activity in human colon carcinoma CBS cells is autoregulated and independent of exogenous epidermal growth factor.
Author:	Jiang, D\|Liang, J\|Humphrey, L E\|Yang, H\|Brattain, M G
PMID:	9525476

68.
Journal:	Gastroenterology. 1998 May;114(5):930-9.
Title:	Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells.
Author:	Karnes, W E Jr\|Weller, S G\|Adjei, P N\|Kottke, T J\|Glenn, K S\|Gores, G J\|Kaufmann, S H
PMID:	9558281

69.
Journal:	Clin Cancer Res. 1998 Apr;4(4):821-8.
Title:	Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications.
Author:	Ciardiello, F\|Tortora, G
PMID:	9563874

70.
Journal:	Br J Cancer. 1998 Jun;77(11):1792-8.
Title:	Epidermal growth factor receptor expression in primary cultured human colorectal carcinoma cells.
Author:	Tong, W M\|Ellinger, A\|Sheinin, Y\|Cross, H S
PMID:	9667648

71.
Journal:	Acta Oncol. 1998;37(3):285-9.
Title:	EGF, TGF-alpha, and EGF-R in human colorectal adenocarcinoma.
Author:	Messa, C\|Russo, F\|Caruso, M G\|Di Leo, A
PMID:	9677101

72.
Journal:	Hepatogastroenterology. 1998 May-Jun;45(21):733-7.
Title:	Enhanced ligand-induced activation of EGF-receptor and overall tyrosine kinase and phospholipase C in colonocytes isolated from azoxymethane-treated rats.
Author:	Malecka-Panas, E\|Tureaud, J\|Majumdar, A P
PMID:	9684124

73.
Journal:	Anticancer Res. 1998 Jul-Aug;18(4A):2297-300.
Title:	Inhibition of human colon cancer malignant cell behavior and growth by antisense epidermal growth factor receptor expression vector.
Author:	Wang, H M\|Rajagopal, S\|Chakrabarty, S
PMID:	9703869

74.
Journal:	Hum Pathol. 1998 Aug;29(8):771-7.
Title:	Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2.
Author:	Maurer, C A\|Friess, H\|Kretschmann, B\|Zimmermann, A\|Stauffer, A\|Baer, H U\|Korc, M\|Buchler, M W
PMID:	9712416

75.
Journal:	J Gastroenterol Hepatol. 1998 Aug;13(8):794-800.
Title:	A comparative study of nucleolar organizer region, proliferating cell nuclear antigen and epidermal growth factor receptor staining in colon tumours.
Author:	Shimada, N\|Suzuki, J\|Fujita, J\|Kawakami, Y\|Tsukakoshi, H\|Hosokawa, M\|Sato, N
PMID:	9736172

76.
Journal:	Nihon Geka Gakkai Zasshi. 1998 Jul;99(7):402-8.
Title:	[Dysfunction of E-cadherin-catenin system in invasion and metastasis of colorectal cancer].
Author:	Maruyama, K\|Ochiai, A\|Nakamura, S\|Baba, S\|Hirohashi, S
PMID:	9742518

77.
Journal:	Oncogene. 1998 Aug 27;17(8):999-1007.
Title:	Nuclear targeting of Bax during apoptosis in human colorectal cancer cells.
Author:	Mandal, M\|Adam, L\|Mendelsohn, J\|Kumar, R
PMID:	9747879

78.
Journal:	Hepatology. 1998 Oct;28(4):971-9.
Title:	Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and Ki67 in colorectal liver metastases and corresponding primary tumors.
Author:	De Jong, K P\|Stellema, R\|Karrenbeld, A\|Koudstaal, J\|Gouw, A S\|Sluiter, W J\|Peeters, P M\|Slooff, M J\|De Vries, E G
PMID:	9755233

79.
Journal:	Invasion Metastasis. 1998-1999;18(3):155-64.
Title:	Serum obtained from rats after partial hepatectomy enhances growth of cultured colon carcinoma cells.
Author:	de Jong, K P\|Brouwers, M A\|van Veen, M L\|Brinker, M\|de Vries, E G\|Daemen, T\|Scherphof, G L\|Slooff, M J
PMID:	10474028

80.
Journal:	Zhonghua Bing Li Xue Za Zhi. 1998 Feb;27(1):43-5.
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PMID:	11244942

81.
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Title:	Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225.
Author:	Ciardiello, F\|Bianco, R\|Damiano, V\|De Lorenzo, S\|Pepe, S\|De Placido, S\|Fan, Z\|Mendelsohn, J\|Bianco, A R\|Tortora, G
PMID:	10213228

82.
Journal:	Br J Cancer. 1999 Jun;80(7):1012-9.
Title:	Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis.
Author:	Damstrup, L\|Kuwada, S K\|Dempsey, P J\|Brown, C L\|Hawkey, C J\|Poulsen, H S\|Wiley, H S\|Coffey, R J Jr
PMID:	10362109

83.
Journal:	Exp Cell Res. 1999 Jul 10;250(1):187-96.
Title:	Role of epidermal growth factor receptor in basal and stimulated colonic epithelial cell migration in vitro.
Author:	Wilson, A J\|Gibson, P R
PMID:	10388532

84.
Journal:	Oncol Rep. 1999 Sep-Oct;6(5):1105-9.
Title:	Synergistic growth inhibition and induction of apoptosis by a novel mixed backbone antisense oligonucleotide targeting CRIPTO in combination with C225 anti-EGFR monoclonal antibody and 8-Cl-cAMP in human GEO colon cancer cells.
Author:	Normanno, N\|Tortora, G\|De Luca, A\|Pomatico, G\|Casamassimi, A\|Agrawal, S\|Mendelsohn, J\|Bianco, A R\|Ciardiello, F
PMID:	10425310

85.
Journal:	Anticancer Res. 1999 May-Jun;19(3A):2147-55.
Title:	Immunohistochemical evaluation of cathepsin D expression in colorectal tumours: a correlation with extracellular matrix components, p53, pRb, bcl-2, c-erbB-2, EGFR and proliferation indices.
Author:	Ioachim, E E\|Goussia, A C\|Machera, M\|Tsianos, E V\|Kappas, A M\|Agnantis, N J
PMID:	10470163

86.
Journal:	Oncol Res. 1999;11(2):77-84.
Title:	Mechanism of antimitogenic action of vitamin D in human colon carcinoma cells: relevance for suppression of epidermal growth factor-stimulated cell growth.
Author:	Tong, W M\|Hofer, H\|Ellinger, A\|Peterlik, M\|Cross, H S
PMID:	10489163

87.
Journal:	Am J Physiol. 1999 Dec;277(6 Pt 1):C1142-8.
Title:	Folic acid inhibition of EGFR-mediated proliferation in human colon cancer cell lines.
Author:	Jaszewski, R\|Khan, A\|Sarkar, F H\|Kucuk, O\|Tobi, M\|Zagnoon, A\|Dhar, R\|Kinzie, J\|Majumdar, A P
PMID:	10600765

88.
Journal:	Anticancer Res. 1999 Jul-Aug;19(4B):3321-5.
Title:	Induction of epidermal growth factor receptor expression and mitogenesis by alcohol in human colon adenocarcinoma-derived Caco-2 cells.
Author:	Tong, W M\|Manhardt, T\|Lassnig, H\|Cross, H S
PMID:	10652628

89.
Journal:	J Clin Pathol. 1999 Dec;52(12):876-9.
Title:	Prognostic evaluation of metallothionein expression in human colorectal neoplasms.
Author:	Ioachim, E E\|Goussia, A C\|Agnantis, N J\|Machera, M\|Tsianos, E V\|Kappas, A M
PMID:	10711249

90.
Journal:	Tumour Biol. 2000 Mar-Apr;21(2):105-15.
Title:	Expression of the tyrosine kinase activity growth factor receptors (EGFR, ERB B2, ERB B3) in colorectal adenocarcinomas and adenomas.
Author:	Porebska, I\|Harlozinska, A\|Bojarowski, T
PMID:	10686540

91.
Journal:	Oncology. 2000 Apr;58(3):242-7.
Title:	Vitamin D receptor gene BsmI polymorphism correlates with erbB-2/HER-2 expression in human rectal cancer.
Author:	Speer, G\|Dworak, O\|Cseh, K\|Bori, Z\|Salamon, D\|Torok, I\|Winkler, G\|Vargha, P\|Nagy, Z\|Takacs, I\|Kucsera, M\|Lakatos, P
PMID:	10765127

92.
Journal:	Oncogene. 2000 Apr 6;19(15):1901-14.
Title:	Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells.
Author:	Yang, H\|Jiang, D\|Li, W\|Liang, J\|Gentry, L E\|Brattain, M G
PMID:	10773880

93.
Journal:	Clin Cancer Res. 2000 Apr;6(4):1439-44.
Title:	Detection of circulating tumor cells in carcinoma patients by a novel epidermal growth factor receptor reverse transcription-PCR assay.
Author:	De Luca, A\|Pignata, S\|Casamassimi, A\|D'Antonio, A\|Gridelli, C\|Rossi, A\|Cremona, F\|Parisi, V\|De Matteis, A\|Normanno, N
PMID:	10778975

94.
Journal:	Clin Cancer Res. 2000 May;6(5):2053-63.
Title:	Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor.
Author:	Ciardiello, F\|Caputo, R\|Bianco, R\|Damiano, V\|Pomatico, G\|De Placido, S\|Bianco, A R\|Tortora, G
PMID:	10815932

95.
Journal:	In Vitro Cell Dev Biol Anim. 2000 Jun;36(6):367-73.
Title:	Microgravity culture reduces apoptosis and increases the differentiation of a human colorectal carcinoma cell line.
Author:	Jessup, J M\|Frantz, M\|Sonmez-Alpan, E\|Locker, J\|Skena, K\|Waller, H\|Battle, P\|Nachman, A\|Bhatti\|Weber, M E\|Thomas, D A\|Curbeam, R L Jr\|Baker, T L\|Goodwin, T J
PMID:	10949995

96.
Journal:	Dis Colon Rectum. 2000 Aug;43(8):1107-15.
Title:	Electrocautery snare resection stimulates cellular proliferation of residual colorectal tumor: an increasing gene expression related to tumor growth.
Author:	Kunihiro, M\|Tanaka, S\|Haruma, K\|Kitadai, Y\|Yoshihara, M\|Sumii, K\|Kajiyama, G\|Nishiyama, M
PMID:	10950009

97.
Journal:	Eur J Cancer Prev. 2000 Aug;9(4):265-8.
Title:	Different expression of some molecular markers in sporadic cancer of the left and right colon.
Author:	Fric, P\|Sovova, V\|Sloncova, E\|Lojda, Z\|Jirasek, A\|Cermak, J
PMID:	10958329

98.
Journal:	Biochem Pharmacol. 2000 Oct 1;60(7):885-98.
Title:	Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors.
Author:	Kraker, A J\|Hartl, B G\|Amar, A M\|Barvian, M R\|Showalter, H D\|Moore, C W
PMID:	10974196

99.
Journal:	Clin Cancer Res. 2000 Sep;6(9):3739-47.
Title:	Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells.
Author:	Ciardiello, F\|Bianco, R\|Damiano, V\|Fontanini, G\|Caputo, R\|Pomatico, G\|De Placido, S\|Bianco, A R\|Mendelsohn, J\|Tortora, G
PMID:	10999768

100.
Journal:	Oncol Rep. 2000 Nov-Dec;7(6):1229-33.
Title:	c-erbB-2 protein expression and clinicopathologic features in colorectal cancer.
Author:	Ishida, H\|Sadahiro, S\|Suzuki, T\|Ishikawa, K\|Tajima, T\|Makuuchi, H
PMID:	11032920

101.
Journal:	Am J Pathol. 2000 Nov;157(5):1523-35.
Title:	Induction of angiogenesis by hyperplastic colonic mucosa adjacent to colon cancer.
Author:	Kuniyasu, H\|Yasui, W\|Shinohara, H\|Yano, S\|Ellis, L M\|Wilson, M R\|Bucana, C D\|Rikita, T\|Tahara, E\|Fidler, I J
PMID:	11073812

102.
Journal:	Clin Cancer Res. 2000 Nov;6(11):4343-50.
Title:	Antitumor activity of combined treatment of human cancer cells with ionizing radiation and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase A antisense oligonucleotide.
Author:	Bianco, C\|Bianco, R\|Tortora, G\|Damiano, V\|Guerrieri, P\|Montemaggi, P\|Mendelsohn, J\|De Placido, S\|Bianco, A R\|Ciardiello, F
PMID:	11106252

103.
Journal:	In Vivo. 2000 Sep-Oct;14(5):587-96.
Title:	The coordinated functional expression of epidermal growth factor receptor and c-Met in colorectal carcinoma metastasis.
Author:	Herynk, M H\|Radinsky, R
PMID:	11125542

104.
Journal:	Dig Dis Sci. 2000 Dec;45(12):2290-7.
Title:	Gastrointestinal tract antigenic profile of cotton-top tamarin, Saguinus oedipus, is similar to that of humans with inflammatory bowel disease.
Author:	Tobi, M\|Chintalapani, S\|Kithier, K\|Clapp, N
PMID:	11258547

105.
Journal:	Int J Surg Investig. 2000;1(6):483-93.
Title:	C-erbB-2 oncoprotein content in colorectal cancer and in surrounding mucosa: relationship with clinicopathologic parameters and prognostic significance.
Author:	Vizoso, F\|Villar, C\|Rodriguez, J C\|Raigoso, P\|Garcia-Muniz, J L\|Allende, M T\|Garcia-Moran, M
PMID:	11729856

106.
Journal:	Zhonghua Zhong Liu Za Zhi. 2000 May;22(3):201-4.
Title:	[Comparative study of metastasis-associated characteristics of tumor cells with different metastatic capacities].
Author:	Shen, Y\|Vogel, I\|Kalthoff, H
PMID:	11778231

107.
Journal:	World J Gastroenterol. 2000 Oct;6(5):747-749.
Title:	Inhibitory effects of EGFR antisense oligodeox ynucleotide in human colorectal cancer cell line.
Author:	He, Yong\|Zhou, Jun\|Wu, Jin-Sheng\|Dou, Ke-Feng
PMID:	11819687

108.
Journal:	Am J Physiol Cell Physiol. 2001 May;280(5):C1083-9.
Title:	Cloning of a novel EGFR-related peptide: a putative negative regulator of EGFR.
Author:	Yu, Y\|Rishi, A K\|Turner, J R\|Liu, D\|Black, E D\|Moshier, J A\|Majumdar, A P
PMID:	11287320

109.
Journal:	Biochim Biophys Acta. 2001 Feb 16;1525(1-2):191-6.
Title:	Construction of tumor-specific cells expressing a membrane-anchored single-chain Fv of anti-ErbB-2 antibody.
Author:	Suzuki, M\|Shinkai, M\|Honda, H\|Kamihira, M\|Iijima, S\|Kobayashi, T
PMID:	11342269

110.
Journal:	Gastroenterology. 2001 Jun;120(7):1713-9.
Title:	Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth.
Author:	Mann, M\|Sheng, H\|Shao, J\|Williams, C S\|Pisacane, P I\|Sliwkowski, M X\|DuBois, R N
PMID:	11375952

111.
Journal:	Orv Hetil. 2001 May 6;142(18):947-51.
Title:	[The role of estrogen receptor, vitamin D receptor and calcium receptor genotypes in the pathogenesis of colorectal cancer].
Author:	Speer, G\|Cseh, K\|Fuszek, P\|Dworak, O\|Vargha, P\|Takacs, I\|Nagy, Z\|Lakatos, P
PMID:	11392075

112.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2001 Jul;281(1):G111-6.
Title:	Increased in vitro activation of EGFR by membrane-bound TGF-alpha from gastric and colonic mucosa of aged rats.
Author:	Xiao, Z Q\|Majumdar, A P
PMID:	11408261

113.
Journal:	J Biol Chem. 2001 Oct 5;276(40):37273-9. Epub 2001 Aug 3.
Title:	Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells.
Author:	Rosen, K\|Coll, M L\|Li, A\|Filmus, J
PMID:	11487584

114.
Journal:	Br J Cancer. 2001 Aug 17;85(4):584-9.
Title:	Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors.
Author:	Shaheen, R M\|Ahmad, S A\|Liu, W\|Reinmuth, N\|Jung, Y D\|Tseng, W W\|Drazan, K E\|Bucana, C D\|Hicklin, D J\|Ellis, L M
PMID:	11506500

115.
Journal:	Eur J Cancer. 2001 Aug;37(12):1463-8.
Title:	Oestrogen and vitamin D receptor (VDR) genotypes and the expression of ErbB-2 and EGF receptor in human rectal cancers.
Author:	Speer, G\|Cseh, K\|Winkler, G\|Takacs, I\|Barna, I\|Nagy, Z\|Lakatos, P
PMID:	11506951

116.
Journal:	Curr Med Chem. 2001 Oct;8(12):1487-503.
Title:	Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents.
Author:	Owa, T\|Yoshino, H\|Yoshimatsu, K\|Nagasu, T
PMID:	11562278

117.
Journal:	World J Surg. 2001 Aug;25(8):996-1001.
Title:	Genetic markers of survival and liver recurrence after resection of liver metastases from colorectal cancer.
Author:	Crowe, P J\|Yang, J L\|Berney, C R\|Erskine, C\|Ham, J M\|Fisher, R\|Russell, P J
PMID:	11571982

118.
Journal:	Eur J Cancer. 2001 Sep;37 Suppl 4:S9-15.
Title:	EGFR and cancer prognosis.
Author:	Nicholson, R I\|Gee, J M\|Harper, M E
PMID:	11597399

119.
Journal:	Eur J Cancer. 2001 Sep;37 Suppl 4:S16-22.
Title:	The EGFR as a target for anticancer therapy--focus on cetuximab.
Author:	Baselga, J
PMID:	11597400

120.
Journal:	Oncol Rep. 2001 Nov-Dec;8(6):1409-13.
Title:	Upregulation of non-mutated H-ras and its upstream and downstream signaling proteins in colorectal cancer.
Author:	Feng, J\|Hua, F\|Shuo, R\|Chongfeng, G\|Huimian, X\|Nakajima, T\|Subao, W\|Tsuchida, N
PMID:	11605075

121.
Journal:	Acta Oncol. 2001;40(5):633-7.
Title:	Microsatellite instability, PTEN and p53 germline mutations in glioma families.
Author:	Malmer, B\|Gronberg, H\|Andersson, U\|Jonsson, B A\|Henriksson, R
PMID:	11669337

122.
Journal:	J Biol Chem. 2002 Jan 4;277(1):75-86. Epub 2001 Oct 29.
Title:	Differences in sensitivity of biological functions mediated by epidermal growth factor receptor activation with respect to endogenous and exogenous ligands.
Author:	Sawhney, Rajinder S\|Zhou, Guo-Hao K\|Humphrey, Lisa E\|Ghosh, Paramita\|Kreisberg, Jeffrey I\|Brattain, Michael G
PMID:	11684674

123.
Journal:	Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1521-6. Epub 2002 Jan 29.
Title:	Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis.
Author:	Roberts, Reade B\|Min, Lu\|Washington, M Kay\|Olsen, Sandra J\|Settle, Stephen H\|Coffey, Robert J\|Threadgill, David W
PMID:	11818567

124.
Journal:	Br J Cancer. 2002 Feb 12;86(4):568-73.
Title:	c-erbB-2 is not a major factor in the development of colorectal cancer.
Author:	McKay, J A\|Loane, J F\|Ross, V G\|Ameyaw, M-M\|Murray, G I\|Cassidy, J\|McLeod, H L
PMID:	11870539

125.
Journal:	Nat Med. 2002 Mar;8(3):289-93.
Title:	Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy.
Author:	Pai, Rama\|Soreghan, Brian\|Szabo, Imre L\|Pavelka, Meredith\|Baatar, Dolgor\|Tarnawski, Andrzej S
PMID:	11875501

126.
Journal:	Am J Pathol. 2002 Mar;160(3):1129-41.
Title:	Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas.
Author:	Niki, Toshiro\|Kohno, Takashi\|Iba, Sanae\|Moriya, Yasumitsu\|Takahashi, Yoko\|Saito, Miyuki\|Maeshima, Arafumi\|Yamada, Tesshi\|Matsuno, Yoshihiro\|Fukayama, Masashi\|Yokota, Jun\|Hirohashi, Setsuo
PMID:	11891209

127.
Journal:	Nihon Rinsho. 2002 Mar;60(3):539-44.
Title:	[Clinical assessment of monoclonal antibodies for the treatment and diagnosis of colorectal cancers].
Author:	Koda, Keiji\|Miyazaki, Masaru
PMID:	11904970

128.
Journal:	Nihon Geka Gakkai Zasshi. 2002 Feb;103(2):233-6.
Title:	[Molecular target-based cancer therapy: epidermal growth factor receptor inhibitors].
Author:	Tamura, Tomohide
PMID:	11904986

129.
Journal:	Gastroenterology. 2002 Apr;122(4):985-93.
Title:	Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line.
Author:	Yoon, Jung-Hwan\|Higuchi, Hajime\|Werneburg, Nathan W\|Kaufmann, Scott H\|Gores, Gregory J
PMID:	11910351

130.
Journal:	Oncogene. 2002 Apr 25;21(18):2785-96.
Title:	Activation of the TGFalpha autocrine loop is downstream of IGF-I receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells.
Author:	Wang, Degeng\|Patil, Sandip\|Li, Wenhui\|Humphrey, Lisa E\|Brattain, Michael G\|Howell, Gillian M
PMID:	11973637

131.
Journal:	Eur J Cancer. 2002 May;38(7):1000-15.
Title:	Systemic treatment of colorectal cancer.
Author:	Tebbutt, N C\|Cattell, E\|Midgley, R\|Cunningham, D\|Kerr, D
PMID:	11978525

132.
Journal:	Br J Cancer. 2002 May 6;86(9):1518-23.
Title:	Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 ("Iressa").
Author:	Magne, N\|Fischel, J L\|Dubreuil, A\|Formento, P\|Poupon, M-F\|Laurent-Puig, P\|Milano, G
PMID:	11986789

133.
Journal:	Clin Cancer Res. 2002 May;8(5):994-1003.
Title:	Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts.
Author:	Prewett, Marie C\|Hooper, Andrea T\|Bassi, Rajiv\|Ellis, Lee M\|Waksal, Harlan W\|Hicklin, Daniel J
PMID:	12006511

134.
Journal:	Eur J Cancer. 2002 May;38(8):1065-71.
Title:	Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery.
Author:	Lee, J C\|Wang, S-T\|Chow, N-H\|Yang, H-B
PMID:	12008194

135.
Journal:	Int J Colorectal Dis. 2002 Jan;17(1):20-4.
Title:	Calcium-sensing receptor A986S polymorphism in human rectal cancer.
Author:	Speer, G\|Cseh, K\|Mucsi, K\|Takacs, I\|Dworak, O\|Winkler, G\|Szody, R\|Tisler, A\|Lakatos, P
PMID:	12018449

136.
Journal:	J R Coll Surg Edinb. 2002 Apr;47(2):458-74.
Title:	Current concepts in immunotherapy for the treatment of colorectal cancer.
Author:	Indar, A\|Maxwell-Armstrong, C A\|Durrant, L G\|Carmichael, J\|Scholefield, J H
PMID:	12018689

137.
Journal:	Semin Oncol Nurs. 2002 May;18(2 Suppl 2):20-9.
Title:	The role of the epidermal growth factor receptor in the treatment of colorectal carcinoma.
Author:	Waxman, Elizabeth S\|Herbst, Roy S
PMID:	12053861

138.
Journal:	Cancer Res. 2002 Jun 15;62(12):3402-7.
Title:	A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis.
Author:	Casanova, M Llanos\|Larcher, Fernando\|Casanova, Benito\|Murillas, Rodolfo\|Fernandez-Acenero, M Jesus\|Villanueva, Concepcion\|Martinez-Palacio, Jesus\|Ullrich, Axel\|Conti, Claudio J\|Jorcano, Jose Luis
PMID:	12067982

139.
Journal:	Gastroenterol Clin Biol. 2002 Jun-Jul;26(6-7):648-9.
Title:	[Central role of epidermic growth factor receptor (EGFR) in hypertrophic gastropathy and cancer of the colon].
Author:	Desreumaux, P
PMID:	12193872

140.
Journal:	Clin Exp Metastasis. 2002;19(5):401-7.
Title:	Overexpression of c-erbB-2 protein correlates with chromosomal gain at the c-erbB-2 locus and patient survival in advanced colorectal carcinomas.
Author:	Knosel, Thomas\|Yu, Youngwei\|Stein, Ulrike\|Schwabe, Holger\|Schluns, Karsten\|Schlag, Peter Michael\|Dietel, Manfred\|Petersen, Iver
PMID:	12198768

141.
Journal:	Clin Cancer Res. 2002 Oct;8(10):3250-8.
Title:	Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa).
Author:	Bianco, Cataldo\|Tortora, Giampaolo\|Bianco, Roberto\|Caputo, Roberta\|Veneziani, Bianca Maria\|Caputo, Rosa\|Damiano, Vincenzo\|Troiani, Teresa\|Fontanini, Gabriella\|Raben, David\|Pepe, Stefano\|Bianco, A Raffaele\|Ciardiello, Fortunato
PMID:	12374696

142.
Journal:	J Clin Oncol. 2002 Nov 1;20(21):4292-302.
Title:	Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types.
Author:	Baselga, J\|Rischin, D\|Ranson, M\|Calvert, H\|Raymond, E\|Kieback, D G\|Kaye, S B\|Gianni, L\|Harris, A\|Bjork, T\|Averbuch, S D\|Feyereislova, A\|Swaisland, H\|Rojo, F\|Albanell, J
PMID:	12409327

143.
Journal:	Br Med Bull. 2002;64:227-54.
Title:	Therapeutics targeting signal transduction for patients with colorectal carcinoma.
Author:	de Bono, Johann S\|Rowinsky, Eric K
PMID:	12421735

144.
Journal:	Semin Oncol. 2002 Oct;29(5 Suppl 15):34-9.
Title:	The role of oxaliplatin in the treatment of advanced metastatic colorectal cancer: prospects and future directions.
Author:	Schmoll, H J
PMID:	12422306

145.
Journal:	Semin Oncol. 2002 Oct;29(5 Suppl 14):10-7.
Title:	Epidermal growth factor receptor-targeted therapy in colorectal cancer.
Author:	O'dwyer, Peter J\|Benson, Al B 3rd
PMID:	12422309

146.
Journal:	Semin Oncol. 2002 Oct;29(5 Suppl 14):45-54.
Title:	Epidermal growth factor receptor expression and measurement in solid tumors.
Author:	Spaulding, David C\|Spaulding, Betsy O
PMID:	12422313

147.
Journal:	Semin Oncol. 2002 Oct;29(5 Suppl 14):55-60.
Title:	Safety experience with IMC-C225, an anti-epidermal growth factor receptor antibody.
Author:	Needle, Michael N
PMID:	12422314

148.
Journal:	Cell Cycle. 2002 Jan;1(1):90-6.
Title:	The cyclin-dependent kinase inhibitor butyrolactone is a potent inhibitor of p21 (WAF1/CIP1 expression).
Author:	Sax, Joanna K\|Dash, Bipin C\|Hong, Rui\|Dicker, David T\|El-Deiry, Wafik S
PMID:	12429914

149.
Journal:	Eur J Cancer. 2002 Nov;38(17):2258-64.
Title:	Evaluation of the epidermal growth factor receptor (EGFR) in colorectal tumours and lymph node metastases.
Author:	McKay, J A\|Murray, L J\|Curran, S\|Ross, V G\|Clark, C\|Murray, G I\|Cassidy, J\|McLeod, H L
PMID:	12441262

150.
Journal:	Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1460-5.
Title:	Epidermal growth factor receptor is a predictor of tumor response in locally advanced rectal cancer patients treated with preoperative radiotherapy.
Author:	Giralt, Jordi\|Eraso, Aranzazu\|Armengol, Manel\|Rossello, Jose\|Majo, Joaquin\|Ares, Carmen\|Espin, Eloi\|Benavente, Sergio\|de Torres, Ines
PMID:	12459370

151.
Journal:	Lung Cancer. 2002 Dec;38 Suppl 4:43-9.
Title:	Molecular markers and targeted therapy with novel agents: prospects in the treatment of non-small cell lung cancer.
Author:	Rosell, Rafael\|Fossella, Frank\|Milas, Luka
PMID:	12480194

152.
Journal:	Carcinogenesis. 2002 Dec;23(12):2063-80.
Title:	Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Author:	Crowley-Weber, Cara L\|Payne, Claire M\|Gleason-Guzman, Mary\|Watts, George S\|Futscher, Bernard\|Waltmire, Caroline N\|Crowley, Cheray\|Dvorakova, Katerina\|Bernstein, Carol\|Craven, Mary\|Garewal, Harinder\|Bernstein, Harris
PMID:	12507930

153.
Journal:	Hematol Oncol Clin North Am. 2002 Oct;16(5):1041-63.
Title:	Epithelial growth factor receptor interacting agents.
Author:	Baselga, Jose\|Albanell, Joan
PMID:	12512382

154.
Journal:	Adv Exp Med Biol. 2002;507:403-7.
Title:	Growth stimulation and epidermal growth factor receptor induction in cyclooxygenase-overexpressing human colon carcinoma cells.
Author:	Yoshimoto, Tanihiro\|Takahashi, Yoshitaka\|Kinoshita, Takahiro\|Sakashita, Toshiki\|Inoue, Hiroyasu\|Tanabe, Tadashi
PMID:	12664617

155.
Journal:	Oncol Rep. 2003 Jan-Feb;10(1):217-22.
Title:	Detection of CK19, CK20 and EGFR mRNAs in peripheral blood of carcinoma patients: correlation with clinical stage of disease.
Author:	Gradilone, Angela\|Gazzaniga, Paola\|Silvestri, Ida\|Gandini, Orietta\|Trasatti, Luciana\|Lauro, Salvatore\|Frati, Luigi\|Agliano, Anna Maria
PMID:	12469172

156.
Journal:	Int J Oncol. 2003 Feb;22(2):425-30.
Title:	Epidermal growth factor receptor mRNA in peripheral blood of patients with pancreatic, lung, and colon carcinomas detected by RT-PCR.
Author:	Clarke, Loren E\|Leitzel, Kim\|Smith, Jill\|Ali, Suhail M\|Lipton, Allan
PMID:	12527944

157.
Journal:	Cancer. 2003 Feb 15;97(4):960-8.
Title:	Vascular endothelial growth factor, CD68, and epidermal growth factor receptor expression and survival in patients with Stage II and Stage III colon carcinoma: a role for the host response in prognosis.
Author:	Khorana, Alok A\|Ryan, Charlotte K\|Cox, Christopher\|Eberly, Shirley\|Sahasrabudhe, Deepak M
PMID:	12569594

158.
Journal:	Clin Colorectal Cancer. 2003 Feb;2(4):246-51.
Title:	Epidermal growth factor receptor as a therapeutic target in colorectal cancer.
Author:	Cohen, Roger B
PMID:	12620146

159.
Journal:	Anticancer Res. 2003 Jan-Feb;23(1A):179-86.
Title:	Investigations for a multi-marker RT-PCR to improve sensitivity of disseminated tumor cell detection.
Author:	Vlems, F A\|Diepstra, J H S\|Cornelissen, I M H A\|Ligtenberg, M J L\|Wobbes, Th\|Punt, C J A\|van Krieken, J H J M\|Ruers, T J M\|van Muijen, G N P
PMID:	12680210

160.
Journal:	Clin Cancer Res. 2003 Apr;9(4):1546-56.
Title:	Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase.
Author:	Ciardiello, Fortunato\|Caputo, Rosa\|Damiano, Vincenzo\|Caputo, Roberta\|Troiani, Teresa\|Vitagliano, Donatella\|Carlomagno, Francesca\|Veneziani, Bianca Maria\|Fontanini, Gabriella\|Bianco, A Raffaele\|Tortora, Giampaolo
PMID:	12684431

161.
Journal:	Clin Cancer Res. 2003 Apr;9(4):1566-72.
Title:	Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect.
Author:	Tortora, Giampaolo\|Caputo, Rosa\|Damiano, Vincenzo\|Melisi, Davide\|Bianco, Roberto\|Fontanini, Gabriella\|Veneziani, Bianca Maria\|De Placido, Sabino\|Bianco, A Raffaele\|Ciardiello, Fortunato
PMID:	12684433

162.
Journal:	Cancer Sci. 2003 Feb;94(2):166-72.
Title:	Redifferentiation and ZO-1 reexpression in liver-metastasized colorectal cancer: possible association with epidermal growth factor receptor-induced tyrosine phosphorylation of ZO-1.
Author:	Kaihara, Tsukasa\|Kawamata, Hitoshi\|Imura, Johji\|Fujii, Shigehiko\|Kitajima, Kazuaki\|Omotehara, Fumie\|Maeda, Naomi\|Nakamura, Tetsuya\|Fujimori, Takahiro
PMID:	12708492

163.
Journal:	Gastroenterology. 2003 May;124(5):1337-47.
Title:	Epidermal growth factor receptor-related protein: a potential therapeutic agent for colorectal cancer.
Author:	Marciniak, Dorota J\|Moragoda, Lathika\|Mohammad, Ramzi M\|Yu, Yingjie\|Nagothu, Kiran K\|Aboukameel, Amro\|Sarkar, Fazlul H\|Adsay, Volkan N\|Rishi, Arun K\|Majumdar, Adhip P n
PMID:	12730874

164.
Journal:	J Cancer Res Clin Oncol. 2003 May;129(5):272-8. Epub 2003 May 14.
Title:	Growth-promoting effect of muscarinic acetylcholine receptors in colon cancer cells.
Author:	Ukegawa, J-I\|Takeuchi, Y\|Kusayanagi, S\|Mitamura, K
PMID:	12748850

165.
Journal:	Recent Results Cancer Res. 2003;162:115-32.
Title:	Clinical implications of the EGF receptor/ligand system for tumor progression and survival in gastrointestinal carcinomas: evidence for new therapeutic options.
Author:	Kopp, Reinhard\|Rothbauer, Elisabeth\|Ruge, Maximilian\|Arnholdt, Hans\|Spranger, Joachim\|Muders, M\|Pfeiffer, Doris G\|Schildberg, Friedrich Wilhelm\|Pfeiffer, Andreas
PMID:	12790326

166.
Journal:	Semin Oncol. 2003 Jun;30(3 Suppl 6):17-22.
Title:	Development of ZD1839 in colorectal cancer.
Author:	Douglass, Edwin C
PMID:	12802791

167.
Journal:	Semin Oncol. 2003 Jun;30(3 Suppl 6):56-67.
Title:	Signaling inhibition with radiation in colorectal cancer: clinical trials.
Author:	McKenna, W Gillies\|Muschel, Ruth J\|Gupta, Anjali\|Hahn, Stephen\|Bernhard, Eric J
PMID:	12802796

168.
Journal:	Ann Oncol. 2003;14 Suppl 2:ii17-23.
Title:	Irinotecan in metastatic colorectal cancer: dose intensification and combination with new agents, including biological response modifiers.
Author:	Ducreux, M\|Kohne, C-H\|Schwartz, G K\|Vanhoefer, U
PMID:	12810453

169.
Journal:	Tidsskr Nor Laegeforen. 2003 May 29;123(11):1514-7.
Title:	[Chemoprevention: treatment of persons at high risk of cancer].
Author:	Sudbo, Jon
PMID:	12822011

170.
Journal:	J Biol Chem. 2003 Sep 12;278(37):35451-7. Epub 2003 Jun 24.
Title:	Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor.
Author:	Buchanan, F Gregory\|Wang, Dingzhi\|Bargiacchi, Francesca\|DuBois, Raymond N
PMID:	12824187

171.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2003 Apr;32(2):115-9.
Title:	[Overexpression of c-erbB-2 and hypoexpression of nm23 relating to poor prognosis of colorectal carcinoma].
Author:	Zhang, Jian-bing\|Chen, Li\|Han, Fang\|Yu, Lan\|He, Song\|Zhou, Jian-yun
PMID:	12839671

172.
Journal:	Clin Cancer Res. 2003 Jul;9(7):2457-64.
Title:	A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.
Author:	Daneshmand, Manijeh\|Parolin, Doris A E\|Hirte, Holger W\|Major, Pierre\|Goss, Glenwood\|Stewart, David\|Batist, Gerald\|Miller, Wilson H Jr\|Matthews, Sarah\|Seymour, Lesley\|Lorimer, Ian A J
PMID:	12855618

173.
Journal:	Clin Cancer Res. 2003 Jul;9(7):2678-82.
Title:	Persistence of epidermal growth factor receptor and interleukin 10 in blood of colorectal cancer patients after surgery identifies patients with high risk to relapse.
Author:	Giacomelli, Luciano\|Gianni, Walter\|Belfiore, Cristiano\|Gandini, Orietta\|Repetto, Lazzaro\|Filippini, Angelo\|Frati, Luigi\|Agliano, Anna Maria\|Gazzaniga, Paola
PMID:	12855647

174.
Journal:	J Clin Oncol. 2003 Jul 15;21(14):2787-99.
Title:	Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer.
Author:	Mendelsohn, John\|Baselga, Jose
PMID:	12860957

175.
Journal:	Mol Pharmacol. 2003 Aug;64(2):382-94.
Title:	Molecular modes of action of artesunate in tumor cell lines.
Author:	Efferth, Thomas\|Sauerbrey, Axel\|Olbrich, Armin\|Gebhart, Erich\|Rauch, Pia\|Weber, H Oliver\|Hengstler, Jan G\|Halatsch, Marc-Eric\|Volm, Manfred\|Tew, Kenneth D\|Ross, Douglas D\|Funk, Jens Oliver
PMID:	12869643

176.
Journal:	Oncogene. 2003 Jul 17;22(29):4488-97.
Title:	Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells.
Author:	Rodrigues, Sylvie\|Attoub, Samir\|Nguyen, Quang-De\|Bruyneel, Erik\|Rodrigue, Christelle M\|Westley, Bruce R\|May, Felicity E B\|Thim, Lars\|Mareel, Marc\|Emami, Shahin\|Gespach, Christian
PMID:	12881705

177.
Journal:	J Cell Physiol. 2003 Sep;196(3):454-63.
Title:	Gastrin and EGF synergistically induce cyclooxygenase-2 expression in Swiss 3T3 fibroblasts that express the CCK2 receptor.
Author:	Slice, Lee W\|Hodikian, Raffi\|Zhukova, Elena
PMID:	12891702

178.
Journal:	Biochem Pharmacol. 2003 Aug 15;66(4):551-63.
Title:	Characterization of sequence-dependent synergy between ZD1839 ("Iressa") and oxaliplatin.
Author:	Xu, Jian-Ming\|Azzariti, Amalia\|Severino, Montemuro\|Lu, Bing\|Colucci, Giuseppe\|Paradiso, Angelo
PMID:	12906920

179.
Journal:	Cancer Res. 2003 Aug 1;63(15):4731-8.
Title:	The role of transforming growth factor alpha in determining growth factor independence.
Author:	Awwad, Rana A\|Sergina, Natalia\|Yang, Haisu\|Ziober, Barry\|Willson, James K V\|Zborowska, Elizabeth\|Humphrey, Lisa E\|Fan, Robert\|Ko, Tien C\|Brattain, Michael G\|Howell, Gillian M
PMID:	12907656

180.
Journal:	Curr Treat Options Oncol. 2003 Oct;4(5):393-403.
Title:	New targeted therapies in gastrointestinal cancers.
Author:	Gill, Sharlene\|Thomas, Rebecca R\|Goldberg, Richard M
PMID:	12941199

181.
Journal:	FASEB J. 2003 Sep;17(12):1640-7.
Title:	Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.
Author:	Pai, Rama\|Nakamura, Toshikazu\|Moon, Woo S\|Tarnawski, Andrzej S
PMID:	12958170

182.
Journal:	Dis Colon Rectum. 2003 Oct;46(10):1391-9.
Title:	Reduced survival of rectal cancer patients with increased tumor epidermal growth factor receptor levels.
Author:	Kopp, Reinhard\|Rothbauer, Elisabeth\|Mueller, Elisabeth\|Schildberg, Friedrich Wilhelm\|Jauch, Karl-Walter\|Pfeiffer, Andreas
PMID:	14530681

183.
Journal:	Nihon Geka Gakkai Zasshi. 2003 Oct;104(10):730-4.
Title:	[Treatment of metastatic liver carcinoma: chemotherapy and immunotherapy].
Author:	Omura, Kenji
PMID:	14579760

184.
Journal:	Cancer Res. 2003 Oct 15;63(20):6744-50.
Title:	Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells.
Author:	Cheng, Kunrong\|Zimniak, Piotr\|Raufman, Jean-Pierre
PMID:	14583469

185.
Journal:	J Cell Biol. 2003 Nov 24;163(4):847-57.
Title:	Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK.
Author:	Conacci-Sorrell, Maralice\|Simcha, Inbal\|Ben-Yedidia, Tamar\|Blechman, Janna\|Savagner, Pierre\|Ben-Ze'ev, Avri
PMID:	14623871

186.
Journal:	Onkologie. 2003 Dec;26 Suppl 7:70-4.
Title:	[Novel molecular approaches in the therapy of advanced colorectal carcinoma].
Author:	Vanhoefer, U
PMID:	14716146

187.
Journal:	Dig Dis. 2003;21(4):320-5.
Title:	Molecular detection of circulating cancer cells. Role in diagnosis, prognosis and follow-up of colon cancer patients.
Author:	Molnar, Bela\|Sipos, Ferenc\|Galamb, Orsolya\|Tulassay, Zsolt
PMID:	14752222

188.
Journal:	Wei Sheng Yan Jiu. 2003 Nov;32(6):581-8.
Title:	[Studies on cancer chemoprevention by tea pigments].
Author:	Han, Chi\|Jia, Xudong
PMID:	14963910

189.
Journal:	Drugs Today (Barc). 2003;39 Suppl C:1-16.
Title:	Monoclonal antibodies in human cancer.
Author:	Mellstedt, H
PMID:	14988743

190.
Journal:	Drugs Today (Barc). 2003;39 Suppl C:61-80.
Title:	The epidermal growth factor receptor pathway and its inhibition as anticancer therapy.
Author:	Janmaat, M L\|Giaccone, G
PMID:	14988746

191.
Journal:	Colorectal Dis. 2003 Nov;5 Suppl 3:1-9.
Title:	New oxaliplatin-based combinations in the treatment of colorectal cancer.
Author:	Cassidy, J\|Hochster, H
PMID:	23573555

192.
Journal:	J Pharmacol Exp Ther. 2004 Jan;308(1):66-72. Epub 2003 Oct 20.
Title:	Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway.
Author:	Ye, Yi N\|Liu, Edgar S L\|Shin, Vivian Y\|Wu, William K K\|Luo, Jiing C\|Cho, Chi H
PMID:	14569062

193.
Journal:	Int J Cancer. 2004 Jan 20;108(3):464-72.
Title:	Synergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib ("Iressa") and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells.
Author:	Koizumi, Fumiaki\|Kanzawa, Fumihiko\|Ueda, Yutaka\|Koh, Yasuhiro\|Tsukiyama, Shoji\|Taguchi, Fumiko\|Tamura, Tomohide\|Saijo, Nagahiro\|Nishio, Kazuto
PMID:	14648715

194.
Journal:	Gut. 2004 Jan;53(1):123-9.
Title:	Regulation of epidermal growth factor receptor in human colon cancer cell lines by interferon alpha.
Author:	Yang, J-L\|Qu, X-J\|Russell, P J\|Goldstein, D
PMID:	14684586

195.
Journal:	Int J Cancer. 2004 Feb 10;108(4):540-8.
Title:	HER-2 receptor expression, localization, and activation in colorectal cancer cell lines and human tumors.
Author:	Half, Elizabeth\|Broaddus, Russell\|Danenberg, Kathleen D\|Danenberg, Peter V\|Ayers, Gregory D\|Sinicrope, Frank A
PMID:	14696118

196.
Journal:	Int J Oncol. 2004 Feb;24(2):241-8.
Title:	The expression and prognostic significance of HER-2 in colorectal cancer and its relationship with clinicopathological parameters.
Author:	Essapen, Sharadah\|Thomas, Hilary\|Green, Margaret\|De Vries, Corrine\|Cook, Martin G\|Marks, Christopher\|Topham, Clare\|Modjtahedi, Helmout
PMID:	14719098

197.
Journal:	Drugs. 2004;64(1):109-18; discussion 119-121.
Title:	Cetuximab: in the treatment of metastatic colorectal cancer.
Author:	Reynolds, Neil A\|Wagstaff, Antona J
PMID:	14723561

198.
Journal:	J Biol Chem. 2004 Apr 2;279(14):14287-93. Epub 2004 Jan 23.
Title:	Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells.
Author:	Shao, Jinyi\|Evers, B Mark\|Sheng, Hongmiao
PMID:	14742435

199.
Journal:	J Nutr. 2004 Feb;134(2):483-6.
Title:	Ursodeoxycholic acid (UDCA) can inhibit deoxycholic acid (DCA)-induced apoptosis via modulation of EGFR/Raf-1/ERK signaling in human colon cancer cells.
Author:	Im, Eunok\|Martinez, Jesse D
PMID:	14747693

200.
Journal:	Int J Cancer. 2004 Mar 20;109(2):291-301.
Title:	Effects of trastuzumab on epidermal growth factor receptor-dependent and -independent human colon cancer cells.
Author:	Kuwada, Scott K\|Scaife, Courtney L\|Kuang, Jinqiu\|Li, Xiufen\|Wong, Robert F\|Florell, Scott R\|Coffey, Robert J Jr\|Gray, Phillip D
PMID:	14750183

201.
Journal:	Clin Cancer Res. 2004 Jan 15;10(2):691-700.
Title:	Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo.
Author:	Nyati, Mukesh K\|Maheshwari, Divya\|Hanasoge, Sheela\|Sreekumar, Arun\|Rynkiewicz, Susan D\|Chinnaiyan, Arul M\|Leopold, Wilbur R\|Ethier, Stephen P\|Lawrence, Theodore S
PMID:	14760092

202.
Journal:	Clin Cancer Res. 2004 Jan 15;10(2):784-93.
Title:	Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.
Author:	Ciardiello, Fortunato\|Bianco, Roberto\|Caputo, Roberta\|Caputo, Rosa\|Damiano, Vincenzo\|Troiani, Teresa\|Melisi, Davide\|De Vita, Ferdinando\|De Placido, Sabino\|Bianco, A Raffaele\|Tortora, Giampaolo
PMID:	14760102

203.
Journal:	J Clin Oncol. 2004 Apr 1;22(7):1177-9.
Title:	Targeting the epidermal growth factor receptor: an important incremental step in the battle against colorectal cancer.
Author:	Ellis, Lee M\|Hoff, Paulo M
PMID:	14993229

204.
Journal:	J Clin Oncol. 2004 Apr 1;22(7):1201-8. Epub 2004 Mar 1.
Title:	Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.
Author:	Saltz, Leonard B\|Meropol, Neal J\|Loehrer, Patrick J Sr\|Needle, Michael N\|Kopit, Justin\|Mayer, Robert J
PMID:	14993230

205.
Journal:	Cancer Lett. 2004 Mar 31;206(1):27-33.
Title:	Folic acid reduces nuclear translocation of beta-catenin in rectal mucosal crypts of patients with colorectal adenomas.
Author:	Jaszewski, Richard\|Millar, Brett\|Hatfield, James S\|Nogothu, Kiran\|Finkenauer, Raphaela\|Rishi, Arun K\|Naumoff, Jo Anne\|Kucuk, Omer\|Axelrod, Bradley N\|Majumdar, Adhip P N
PMID:	15019156

206.
Journal:	Cancer Res. 2004 Apr 1;64(7):2601-9.
Title:	Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.
Author:	Jackson, James G\|St Clair, Patricia\|Sliwkowski, Mark X\|Brattain, Michael G
PMID:	15059917

207.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2004 Sep;287(3):G541-6. Epub 2004 Apr 8.
Title:	Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells.
Author:	Nagothu, Kiran K\|Rishi, Arun K\|Jaszewski, Richard\|Kucuk, Omer\|Majumdar, Adhip P N
PMID:	15075253

208.
Journal:	Oncogene. 2004 Apr 22;23(19):3317-27.
Title:	Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell-cell adhesion complexes.
Author:	Rivat, Christine\|De Wever, Olivier\|Bruyneel, Erik\|Mareel, Marc\|Gespach, Christian\|Attoub, Samir
PMID:	15077188

209.
Journal:	Clin J Oncol Nurs. 2004 Apr;8(2):163-8.
Title:	Epidermal growth factor receptor tyrosine kinase inhibitors: evolving role in the treatment of solid tumors.
Author:	Krozely, Peggy
PMID:	15108418

210.
Journal:	Oncology (Williston Park). 2004 Apr;18(4):479-88; discussion 488, 493, 497
Title:	Epidermal growth factor receptor inhibitors for the treatment of colorectal cancer: a promise fulfilled?
Author:	Damjanov, Nevena\|Meropol, Neal J
PMID:	15134356

211.
Journal:	Int J Radiat Oncol Biol Phys. 2004;59(2 Suppl):2-10.
Title:	Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression.
Author:	Bonner, James A\|Buchsbaum, Donald J\|Russo, Suzanne M\|Fiveash, John B\|Trummell, Hoa Q\|Curiel, David T\|Raisch, Kevin P
PMID:	15142629

212.
Journal:	Mod Pathol. 2004 Aug;17(8):895-904.
Title:	Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study.
Author:	Ooi, Akishi\|Takehana, Takuo\|Li, Xiaoling\|Suzuki, Shioto\|Kunitomo, Kazuyoshi\|Iino, Hiroshi\|Fujii, Hideki\|Takeda, Yasuhisa\|Dobashi, Yoh
PMID:	15143334

213.
Journal:	Biochem Biophys Res Commun. 2004 Jun 18;319(1):1-11.
Title:	The ErbB/HER receptor protein-tyrosine kinases and cancer.
Author:	Roskoski, Robert Jr
PMID:	15158434

214.
Journal:	Am J Pathol. 2004 Jun;164(6):2139-51.
Title:	Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis.
Author:	Parikh, Alexander A\|Fan, Fan\|Liu, Wen Biao\|Ahmad, Syed A\|Stoeltzing, Oliver\|Reinmuth, Niels\|Bielenberg, Diane\|Bucana, Corazon D\|Klagsbrun, Michael\|Ellis, Lee M
PMID:	15161648

215.
Journal:	Biochem Pharmacol. 2004 Jul 1;68(1):135-44.
Title:	The schedule-dependent enhanced cytotoxic activity of 7-ethyl-10-hydroxy-camptothecin (SN-38) in combination with Gefitinib (Iressa, ZD1839).
Author:	Azzariti, Amalia\|Xu, Jian-Ming\|Porcelli, Letizia\|Paradiso, Angelo
PMID:	15183125

216.
Journal:	Clin Colorectal Cancer. 2004 May;4(1):51-62.
Title:	Epidermal growth factor receptor as a therapeutic target for the treatment of colorectal cancer.
Author:	Amador, Maria L\|Hidalgo, Manuel
PMID:	15207021

217.
Journal:	Mol Cancer Ther. 2004 Jun;3(6):755-62.
Title:	Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase.
Author:	Mallon, Robert\|Feldberg, Larry\|Kim, Steven\|Collins, Karen\|Wojciechowicz, Donald\|Kohler, Constance\|Kovacs, Diana\|Discafani, Carolyn\|Zhang, Nan\|Wu, Biqi\|Floyd, Brawner\|Powell, Dennis\|Berger, Dan
PMID:	15210862

218.
Journal:	Histopathology. 2004 Jul;45(1):47-54.
Title:	Cyclooxygenase 2 (COX2) expression is associated with poor outcome in ER-negative, but not ER-positive, breast cancer.
Author:	Witton, C J\|Hawe, S J K\|Cooke, T G\|Bartlett, J M S
PMID:	15228443

219.
Journal:	N Engl J Med. 2004 Jul 22;351(4):337-45.
Title:	Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.
Author:	Cunningham, David\|Humblet, Yves\|Siena, Salvatore\|Khayat, David\|Bleiberg, Harry\|Santoro, Armando\|Bets, Danny\|Mueser, Matthias\|Harstrick, Andreas\|Verslype, Chris\|Chau, Ian\|Van Cutsem, Eric
PMID:	15269313

220.
Journal:	J Biol Chem. 2004 Oct 8;279(41):43261-72. Epub 2004 Aug 4.
Title:	Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Author:	Moran, Amy E\|Hunt, Daniel H\|Javid, Sara H\|Redston, Mark\|Carothers, Adelaide M\|Bertagnolli, Monica M
PMID:	15294912

221.
Journal:	Int J Cancer. 2004 Oct 10;111(6):921-8.
Title:	Immunohistochemical patterns in rectal cancer: application of tissue microarray with prognostic correlations.
Author:	Fernebro, Eva\|Bendahl, Par-Ola\|Dictor, Michael\|Persson, Annette\|Ferno, Marten\|Nilbert, Mef
PMID:	15300804

222.
Journal:	J Biol Chem. 2004 Nov 5;279(45):47379-90. Epub 2004 Aug 10.
Title:	Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells.
Author:	Sawhney, Rajinder S\|Cookson, Michelle M\|Sharma, Bhavya\|Hauser, Jennie\|Brattain, Michael G
PMID:	15304500

223.
Journal:	Cancer Chemother Pharmacol. 2004 Sep;54 Suppl 1:S32-9.
Title:	Integration of novel agents in the treatment of colorectal cancer.
Author:	Iqbal, Syma\|Lenz, Heinz-Josef
PMID:	15309512

224.
Journal:	Cancer Lett. 2004 Sep 30;213(2):249-55.
Title:	Expression of epidermal growth factor-receptor related protein (ERRP) in human colorectal carcinogenesis.
Author:	Jaszewski, Richard\|Levi, Edi\|Sochacki, Paula\|Frank, John\|Kucuk, Omer\|Axelrod, Bradley N\|Majumdar, Adhip P N
PMID:	15327841

225.
Journal:	J Chemother. 2004 Aug;16(4):372-80.
Title:	Effects of paclitaxel and docetaxel on EGFR-expressing human carcinoma cells under normoxic versus hypoxic conditions in vitro.
Author:	Skvortsova, I\|Skvortsov, S\|Haidenberger, A\|Devries, A\|Nevinny-Stickel, M\|Saurer, M\|Lukas, P\|Seppi, T
PMID:	15332713

226.
Journal:	Front Biosci. 2004 Sep 1;9:2725-32.
Title:	Chemopreventive role of folic acid in colorectal cancer.
Author:	Majumdar, Adhip P N\|Kodali, Udayini\|Jaszewski, Richard
PMID:	15353309

227.
Journal:	Mol Cancer Res. 2004 Sep;2(9):514-22.
Title:	Activation of proteinase-activated receptor 1 promotes human colon cancer cell proliferation through epidermal growth factor receptor transactivation.
Author:	Darmoul, Dalila\|Gratio, Valerie\|Devaud, Helene\|Peiretti, Franck\|Laburthe, Marc
PMID:	15383630

228.
Journal:	Expert Opin Pharmacother. 2004 Oct;5(10):2159-70.
Title:	A review of oxaliplatin and its clinical use in colorectal cancer.
Author:	Grothey, Axel\|Goldberg, Richard M
PMID:	15461551

229.
Journal:	ONS News. 2004;19(9 Suppl):53-4.
Title:	EGFR-targeted therapy for patients with colorectal cancer: patient management and future directions.
Author:
PMID:	15478587

230.
Journal:	Int J Oncol. 2004 Nov;25(5):1459-64.
Title:	Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells.
Author:	Sovova, Vlasta\|Kucerova, Dana\|Vojtechova, Martina\|Sloncova, Eva\|Tuhackova, Zdena
PMID:	15492839

231.
Journal:	Anticancer Res. 2004 Sep-Oct;24(5A):2885-91.
Title:	EGF-receptor related protein causes cell cycle arrest and induces apoptosis of colon cancer cells in vitro and in vivo.
Author:	Levi, Edi\|Mohammad, Ramzi\|Kodali, Udayini\|Marciniak, Dorota\|Reddy, Sudha\|Aboukameel, Amro\|Sarkar, Fazlul H\|Kucuk, Omer\|Rishi, Arun K\|Majumdar, Adhip P N
PMID:	15517892

232.
Journal:	Mech Ageing Dev. 2004 Dec;125(12):917-22.
Title:	Age-related loss of EGF-receptor related protein (ERRP) in the aging colon is a potential risk factor for colon cancer.
Author:	Schmelz, Eva M\|Levi, Edi\|Du, Jianhua\|Xu, Hu\|Majumdar, Adhip P N
PMID:	15563939

233.
Journal:	J Clin Oncol. 2004 Dec 1;22(23):4772-8.
Title:	Epidermal growth factor receptor (EGFR) status in primary colorectal tumors does not correlate with EGFR expression in related metastatic sites: implications for treatment with EGFR-targeted monoclonal antibodies.
Author:	Scartozzi, Mario\|Bearzi, Italo\|Berardi, Rossana\|Mandolesi, Alessandra\|Fabris, Guidalberto\|Cascinu, Stefano
PMID:	15570078

234.
Journal:	Cancer Res. 2004 Dec 15;64(24):9139-43.
Title:	An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors.
Author:	Amador, Maria L\|Oppenheimer, Darin\|Perea, Sofia\|Maitra, Anirban\|Cusatis, George\|Iacobuzio-Donahue, Christi\|Baker, Sharyn D\|Ashfaq, Raheela\|Takimoto, Chris\|Forastiere, Arlene\|Hidalgo, Manuel
PMID:	15604284

235.
Journal:	Mol Cancer Ther. 2004 Dec;3(12):1551-8.
Title:	Different proteome pattern of epidermal growth factor receptor-positive colorectal cancer cell lines that are responsive and nonresponsive to C225 antibody treatment.
Author:	Skvortsov, Sergej\|Sarg, Bettina\|Loeffler-Ragg, Judith\|Skvortsova, Ira\|Lindner, Herbert\|Werner Ott, Helmut\|Lukas, Peter\|Illmensee, Karl\|Zwierzina, Heinz
PMID:	15634648

236.
Journal:	Mol Cancer Ther. 2004 Dec;3(12):1615-21.
Title:	Epidermal growth factor receptor-related peptide inhibits growth of PC-3 prostate cancer cells.
Author:	Marciniak, Dorota J\|Rishi, Arun K\|Sarkar, Fazlul H\|Majumdar, Adhip P N
PMID:	15634655

237.
Journal:	Clin Lung Cancer. 2004 Dec;6 Suppl 1:S24-9.
Title:	Select clinical trials of erlotinib (OSI-774) in non-small-cell lung cancer with emphasis on phase III outcomes.
Author:	Fuster, L Minerva Burgos\|Sandler, Alan B
PMID:	15638954

238.
Journal:	Clin Lung Cancer. 2004 Dec;6 Suppl 1:S7-S19.
Title:	Overview of the current status of human epidermal growth factor receptor inhibitors in lung cancer.
Author:	Herbst, Roy S\|Sandler, Alan B
PMID:	15638959

239.
Journal:	Oncology (Williston Park). 2004 Dec;18(14 Suppl 14):35-8.
Title:	Epidermal growth factor receptor inhibitors and colorectal cancer.
Author:	Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	15685832

240.
Journal:	Rev Clin Esp. 2004 Dec;204(12):649-54.
Title:	[Antibodies against cancer].
Author:	Barriuso Feijoo, J\|Sundlov, A\|Gonzalez Baron, M
PMID:	15710074

241.
Journal:	J Natl Compr Canc Netw. 2004 Sep;2 Suppl 2:S74-84.
Title:	Emerging therapies for metastatic colorectal cancer: focus on EGFR and VEGF inhibition.
Author:	Venook, Alan P
PMID:	19780248

242.
Journal:
Title:	(99m)Tc-Cys-Gly-Gly-Affibody ZHER2:342
Author:	Leung, Kam
PMID:	20641196

243.
Journal:
Title:	(111)In-Benzyl-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-ZHER2:342
Author:	Leung, Kam
PMID:	20641264

244.
Journal:
Title:	BODIPY-FL-neutravidin-biotin-Cetuximab
Author:	Leung, Kam
PMID:	20641313

245.
Journal:
Title:	Epidermal growth factor conjugated to near-infrared fluorescent quantum dots
Author:	Chopra, Arvind
PMID:	20641330

246.
Journal:
Title:	Trastuzumab-manganese-doped iron oxide nanoparticles
Author:	Leung, Kam
PMID:	20641351

247.
Journal:
Title:	(111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid- Affibody ZHER2:342-pep2
Author:	Leung, Kam
PMID:	20641379

248.
Journal:
Title:	(99m)Tc- anti-EGFR monoclonal antibody h-R3
Author:
PMID:	20641382

249.
Journal:
Title:	Cy5.5-Trastuzumab
Author:	Leung, Kam
PMID:	20641392

250.
Journal:
Title:	(111)In-Diethylenetriamine pentaacetic acid-pertuzumab
Author:	Leung, Kam
PMID:	20641430

251.
Journal:
Title:	Cetuximab-Oregon Green 488
Author:
PMID:	20641450

252.
Journal:
Title:	(111)In-CHX-A"-diethylenepentaacetic acid-Affibody ZHER2:2395-Cys
Author:	Leung, Kam
PMID:	20641462

253.
Journal:
Title:	(99m)Tc-Hydrazinonicotinamide-epidermal growth factor
Author:	Leung, Kam
PMID:	20641466

254.
Journal:
Title:	Trastuzumab-rhodamine green
Author:	Leung, Kam
PMID:	20641468

255.
Journal:
Title:	(111)In-CHX-A"-Diethylenetriamine pentaacetic acid-(ZEGFR:955)2
Author:	Leung, Kam
PMID:	20641502

256.
Journal:
Title:	(99m)Tc-Ethylenedicysteine-C225
Author:	Leung, Kam
PMID:	20641507

257.
Journal:
Title:	(111)In-Benzyl-diethylenetriaminepentaacetic acid-ZHER2:342
Author:	Leung, Kam
PMID:	20641524

258.
Journal:
Title:	[O-(11)C-methyl]4-N-(3-Bromoanilino)-6,7-dimethoxyquinazoline
Author:	Leung, Kam
PMID:	20641571

259.
Journal:
Title:	(188)Re-Labeled humanized monoclonal anti-epidermal growth factor receptor antibody
Author:	Chopra, Arvind
PMID:	20641577

260.
Journal:
Title:	(64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-cetuximab
Author:	Leung, Kam
PMID:	20641633

261.
Journal:
Title:	(68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-Epidermal growth factor
Author:	Leung, Kam
PMID:	20641634

262.
Journal:
Title:	(111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-AB.Fab4D5
Author:	Leung, Kam
PMID:	20641705

263.
Journal:
Title:	Quantum dot-trastuzumab
Author:	Leung, Kam
PMID:	20641720

264.
Journal:
Title:	(99m)Tc-Affibody ZHER2:2395-Cys
Author:	Leung, Kam
PMID:	20641788

265.
Journal:
Title:	IRDye 800CW-Epidermal growth factor
Author:	Leung, Kam
PMID:	20641801

266.
Journal:
Title:	(111)In-BZ-Diethylenetriaminepentaacetic acid-ZEGFR:1907
Author:	Leung, Kam
PMID:	20641849

267.
Journal:
Title:	Cy5.5 conjugated anti-epidermal growth factor receptor monoclonal antibody
Author:	Chopra, Arvind
PMID:	20641853

268.
Journal:
Title:	(177)Lu-Labeled humanized monoclonal antibody against human epidermal growth factor receptor 2
Author:	Chopra, Arvind
PMID:	20641866

269.
Journal:
Title:	Cy5.5-Epidermal growth factor
Author:	Leung, Kam
PMID:	20641899

270.
Journal:
Title:	(111)In-1,4,7,10-tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395-Cys
Author:	Leung, Kam
PMID:	20641906

271.
Journal:
Title:	IRDye 700DX-Labeled annexin V
Author:	Chopra, Arvind
PMID:	20641913

272.
Journal:
Title:	(99m)Tc-Mercaptoacetyl-Ser-Ser-Ser-Affibody ZHER2:342
Author:	Leung, Kam
PMID:	20641924

273.
Journal:
Title:	(99m)Tc-Mercaptoacetyl-Gly-Gly-Gly-Affibody ZHER2:342
Author:	Leung, Kam
PMID:	20641926

274.
Journal:
Title:	(99m)Tc-Mercaptoacetyl-Glu-Glu-Glu-Affibody ZHER2:342
Author:	Leung, Kam
PMID:	20641930

275.
Journal:
Title:	(125)I-Labeled anti-epidermal growth factor receptor human Fab antibody fragment
Author:	Leung, Kam
PMID:	20642017

276.
Journal:
Title:	Alexa Fluor 750-ZHER2:342 Affibody
Author:	Leung, Kam
PMID:	20662137

277.
Journal:
Title:	DY-682-Albumin-binding domain-fused-ZHER2:342 Affibody
Author:	Leung, Kam
PMID:	20845546

278.
Journal:
Title:	IRDye 800-Anti-epidermal growth factor receptor Affibody
Author:	Leung, Kam
PMID:	20845547

279.
Journal:
Title:	(64)Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-panitumumab
Author:	Leung, Kam
PMID:	20945561

280.
Journal:
Title:	(68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-synthetic HER2 specific Affibody ZHER2:342-pep2
Author:	Leung, Kam
PMID:	21086574

281.
Journal:
Title:	(86)Y-CHX-A''-Diethylenetriamine pentaacetic acid-cetuximab
Author:	Leung, Kam
PMID:	21086575

282.
Journal:
Title:	Alexa Fluor 750-albumin-binding domain-fused-(ZHER2:342)2 Affibody
Author:	Leung, Kam
PMID:	21491705

283.
Journal:
Title:	(124)I-Labeled anti-HER2-specific C6.5 diabody
Author:	Leung, Kam
PMID:	21834183

284.
Journal:
Title:	(86)Y-CHX-A''-diethylenetriamine pentaacetic acid-panitumumab
Author:	Leung, Kam
PMID:	22171389

285.
Journal:
Title:	(18)F-1,4,7-Triazacyclononane-1,4,7-triacetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395
Author:	Leung, Kam
PMID:	22479718

286.
Journal:
Title:	(89)Zr-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12
Author:	Leung, Kam
PMID:	22696779

287.
Journal:
Title:	(68)Ga-Desferrioxamine p-isothiocyanatobenzyl-anti-EGFR nanobody 7D12
Author:	Leung, Kam
PMID:	22696780

288.
Journal:
Title:	(64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu
Author:	Leung, Kam
PMID:	22787682

289.
Journal:
Title:	(64)Cu-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-(Gly-Ser-Gly) -Lys-Cys-Cys-Tyr-Ser-Leu
Author:	Leung, Kam
PMID:	22787683

290.
Journal:
Title:	(64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu
Author:	Leung, Kam
PMID:	22787684

291.
Journal:
Title:	IRDye 800CW-Anti-epidermal growth factor receptor nanobody 7D12
Author:	Leung, Kam
PMID:	22787693

292.
Journal:
Title:	(99m)Tc(CO)3-Anti-epidermal growth factor receptor nanobody 8B6
Author:	Leung, Kam
PMID:	22787694

293.
Journal:
Title:	(64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-epidermal growth factor receptor-binding fibronectin domain E13.4.3'
Author:	Leung, Kam
PMID:	22896860

294.
Journal:
Title:	(111)In/(125)I/(99m)Tc-Labeled N-terminus tri-(histidine-glutamate) (HE)3-tagged and N- or C-terminus hexahistidine (H6)-tagged anti-epidermal growth factor receptor Affibody ZHER2:342-C
Author:	Chopra, Arvind
PMID:	22896861

295.
Journal:
Title:	Cy5.5-Ac-Cys-ZEGFR:1907
Author:	Leung, Kam
PMID:	22973578

296.
Journal:
Title:	[(111)In-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-10-maleimidoethylacetamide-Cys(61)]-Affibody ZHER2:2395
Author:	Leung, Kam
PMID:	22993871

297.
Journal:
Title:	(111)In-2-(4,7,10-Tris(carboxymethyl)-1,4,7,10-tetracyclododecan-1-yl)pentanedioi c acid-Trastuzumab
Author:	Leung, Kam
PMID:	22993872

298.
Journal:
Title:	(64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907
Author:	Leung, Kam
PMID:	23035309

299.
Journal:
Title:	(64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidethylacetamide-Ac-Cys-ZEGFR:1907
Author:	Leung, Kam
PMID:	23035311

300.
Journal:
Title:	QD800-Polyethylene glycol-Cys-ZHER2:342 Affibody
Author:	Leung, Kam
PMID:	23101053

301.
Journal:
Title:	ZHER2:342 Affibody-polyethylene glycol-superparamagnetic iron oxide nanoparticles
Author:	Leung, Kam
PMID:	23101054

302.
Journal:
Title:	N-[2-(4-[(18)F]Fluorobenzamido)ethyl]maleimide-Cys-ZEGFR:1907
Author:	Leung, Kam
PMID:	23136679

303.
Journal:
Title:	(177)Lu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907
Author:	Leung, Kam
PMID:	23166961

304.
Journal:
Title:	Cy5.5-8-Amino-octanoic acid-Ser-Cys-Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH2
Author:	Leung, Kam
PMID:	23166962

305.
Journal:
Title:	(68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-HER2-specific Affibody ZHER2:2891
Author:	Leung, Kam
PMID:	23256220

306.
Journal:
Title:	N(epsilon)-(3-[(131)I]Iodobenzoyl)-Lys(5)-N(alpha)-maleimido-Gly(1)-GEEEK-anti-HE R2 nanobody 5F7GGC
Author:	Leung, Kam
PMID:	23556153

307.
Journal:
Title:	QD800-Anti-epidermal growth factor receptor monoclonal antibody nanoparticles
Author:	Leung, Kam
PMID:	23586108

308.
Journal:
Title:	IRDye 800-albumin-binding domain-fused-ZHER2:342 Affibody
Author:	Leung, Kam
PMID:	23785735

309.
Journal:	J Cancer Res Clin Oncol. 2005 Jan;131(1):49-59.
Title:	Listeria monocytogenes produces a pro-invasive factor that signals via ErbB2/ErbB3 heterodimers.
Author:	Oliveira, Maria Jose\|Lauwaet, Tineke\|De Bruyne, Georges\|Mareel, Marc\|Leroy, Ancy
PMID:	15480783

310.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2005 Mar;288(3):G447-56. Epub 2004 Oct
Title:	Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR.
Author:	Chen, Anping\|Xu, Jianye
PMID:	15486348

311.
Journal:	Ann Oncol. 2005 Jan;16(1):102-8.
Title:	Impact of EGFR expression on colorectal cancer patient prognosis and survival.
Author:	Spano, J-P\|Lagorce, C\|Atlan, D\|Milano, G\|Domont, J\|Benamouzig, R\|Attar, A\|Benichou, J\|Martin, A\|Morere, J-F\|Raphael, M\|Penault-Llorca, F\|Breau, J-L\|Fagard, R\|Khayat, D\|Wind, P
PMID:	15598946

312.
Journal:	Anticancer Drugs. 2005 Feb;16(2):211-21.
Title:	New drugs in cancer therapy, National Tumor Institute, Naples, 17-18 June 2004.
Author:	Caponigro, Francesco\|Basile, Maria\|de Rosa, Vincenzo\|Normanno, Nicola
PMID:	15655420

313.
Journal:	Ann Oncol. 2005 Feb;16(2):189-94.
Title:	Epidermal growth factor receptor signaling in colorectal cancer: preclinical data and therapeutic perspectives.
Author:	Spano, J P\|Fagard, R\|Soria, J-C\|Rixe, O\|Khayat, D\|Milano, G
PMID:	15668269

314.
Journal:	J Clin Oncol. 2005 Mar 20;23(9):1803-10. Epub 2005 Jan 27.
Title:	Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.
Author:	Chung, Ki Young\|Shia, Jinru\|Kemeny, Nancy E\|Shah, Manish\|Schwartz, Gary K\|Tse, Archie\|Hamilton, Audrey\|Pan, Dorothy\|Schrag, Deborah\|Schwartz, Lawrence\|Klimstra, David S\|Fridman, Daniel\|Kelsen, David P\|Saltz, Leonard B
PMID:	15677699

315.
Journal:	Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):600-5.
Title:	Epidermal growth factor receptor gene polymorphisms predict pelvic recurrence in patients with rectal cancer treated with chemoradiation.
Author:	Zhang, Wu\|Park, David J\|Lu, Bo\|Yang, Dong Yun\|Gordon, Michael\|Groshen, Susan\|Yun, Jim\|Press, Oliver A\|Vallbohmer, Daniel\|Rhodes, Katrin\|Lenz, Heinz-Josef
PMID:	15701846

316.
Journal:	Mol Cancer Ther. 2005 Feb;4(2):243-55.
Title:	H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
Author:	Caron, Ruben W\|Yacoub, Adly\|Zhu, Xiaoyu\|Mitchell, Clint\|Han, Song Iy\|Sasazuki, Takehiko\|Shirasawa, Senji\|Hagan, Michael P\|Grant, Steven\|Dent, Paul
PMID:	15713896

317.
Journal:	Curr Oncol Rep. 2005 Mar;7(2):96-103.
Title:	Clinical experience with monoclonal antibodies to epidermal growth factor receptor.
Author:	Calvo, Emiliano\|Rowinsky, Eric K
PMID:	15717942

318.
Journal:	Curr Treat Options Oncol. 2005 Mar;6(2):103-14.
Title:	Rationale and clinical experience with epidermal growth factor receptor inhibitors in gynecologic malignancies.
Author:	Vaidya, Ami P\|Parnes, Aric D\|Seiden, Michael V
PMID:	15717992

319.
Journal:	Cancer Sci. 2005 Feb;96(2):63-8.
Title:	Throwing new light on lung cancer pathogenesis: updates on three recent topics.
Author:	Tomida, Shuta\|Yatabe, Yasushi\|Yanagisawa, Kiyoshi\|Mitsudomi, Tetsuya\|Takahashi, Takashi
PMID:	15723649

320.
Journal:	Semin Oncol. 2005 Feb;32(1):52-60.
Title:	The epidermal growth factor receptor as a target for colorectal cancer therapy.
Author:	Lockhart, A Craig\|Berlin, Jordan D
PMID:	15726506

321.
Journal:	J Med Chem. 2005 Mar 10;48(5):1359-66.
Title:	Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas.
Author:	Kubo, Kazuo\|Shimizu, Toshiyuki\|Ohyama, Shin-ichi\|Murooka, Hideko\|Iwai, Akemi\|Nakamura, Kazuhide\|Hasegawa, Kazumasa\|Kobayashi, Yoshiko\|Takahashi, Noriko\|Takahashi, Kazumi\|Kato, Shinichiro\|Izawa, Toshio\|Isoe, Toshiyuki
PMID:	15743179

322.
Journal:	Invest New Drugs. 2005 Mar;23(2):165-70.
Title:	A phase II trial of ZD1839 (Iressa) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer.
Author:	Mackenzie, Mary J\|Hirte, Holger W\|Glenwood, Goss\|Jean, Maroun\|Goel, Rakesh\|Major, Pierre P\|Miller, Wilson H Jr\|Panasci, Lawrence\|Lorimer, Ian A J\|Batist, Gerald\|Matthews, Sarah\|Douglas, Lynn\|Seymour, Lesley
PMID:	15744593

323.
Journal:	Clin Cancer Res. 2005 Feb 15;11(4):1368-71.
Title:	Somatic mutations of epidermal growth factor receptor in colorectal carcinoma.
Author:	Nagahara, Hisashi\|Mimori, Koshi\|Ohta, Mitsuhiko\|Utsunomiya, Tohru\|Inoue, Hiroshi\|Barnard, Graham F\|Ohira, Masaichi\|Hirakawa, Kosei\|Mori, Masaki
PMID:	15746034

324.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2005 Jul;289(1):G70-8. Epub 2005 Mar 3.
Title:	Extracellular cysteine/cystine redox regulates the p44/p42 MAPK pathway by metalloproteinase-dependent epidermal growth factor receptor signaling.
Author:	Nkabyo, Yvonne S\|Go, Young-Mi\|Ziegler, Thomas R\|Jones, Dean P
PMID:	15746213

325.
Journal:	Cytokine. 2005 Mar 21;29(6):275-82.
Title:	IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells.
Author:	Itoh, Yusuke\|Joh, Takashi\|Tanida, Satoshi\|Sasaki, Makoto\|Kataoka, Hiromi\|Itoh, Keisuke\|Oshima, Tadayuki\|Ogasawara, Naotaka\|Togawa, Shouzo\|Wada, Tsuneya\|Kubota, Hidetsugu\|Mori, Yoshinori\|Ohara, Hirotaka\|Nomura, Tomoyuki\|Higashiyama, Shigeki\|Itoh, Makoto
PMID:	15749028

326.
Journal:	Cancer Res. 2005 Mar 1;65(5):1642-6.
Title:	Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.
Author:	Shigematsu, Hisayuki\|Takahashi, Takao\|Nomura, Masaharu\|Majmudar, Kuntal\|Suzuki, Makoto\|Lee, Huei\|Wistuba, Ignacio I\|Fong, Kwun M\|Toyooka, Shinichi\|Shimizu, Nobuyoshi\|Fujisawa, Takehiko\|Minna, John D\|Gazdar, Adi F
PMID:	15753357

327.
Journal:	J Clin Oncol. 2005 Apr 10;23(11):2445-59.
Title:	Critical update and emerging trends in epidermal growth factor receptor targeting in cancer.
Author:	Baselga, Jose\|Arteaga, Carlos L
PMID:	15753456

328.
Journal:	Mol Nutr Food Res. 2005 Apr;49(4):317-28.
Title:	Inhibitors of the epidermal growth factor receptor in apple juice extract.
Author:	Kern, Melanie\|Tjaden, Zeina\|Ngiewih, Yufanyi\|Puppel, Nicole\|Will, Frank\|Dietrich, Helmut\|Pahlke, Gudrun\|Marko, Doris
PMID:	15759309

329.
Journal:	Clin Cancer Res. 2005 Mar 15;11(6):2398-407.
Title:	Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor.
Author:	Mantha, Angela J\|Hanson, Jennifer E L\|Goss, Glenwood\|Lagarde, Alain E\|Lorimer, Ian A\|Dimitroulakos, Jim
PMID:	15788691

330.
Journal:	Clin Cancer Res. 2005 Apr 1;11(7):2735-46.
Title:	(-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells.
Author:	Shimizu, Masahito\|Deguchi, Atsuko\|Lim, Jin T E\|Moriwaki, Hisataka\|Kopelovich, Levy\|Weinstein, I Bernard
PMID:	15814656

331.
Journal:	Radiother Oncol. 2005 Feb;74(2):101-8.
Title:	The expression of epidermal growth factor receptor results in a worse prognosis for patients with rectal cancer treated with preoperative radiotherapy: a multicenter, retrospective analysis.
Author:	Giralt, Jordi\|de las Heras, Manuel\|Cerezo, Laura\|Eraso, Aranzazu\|Hermosilla, Edurado\|Velez, Dolores\|Lujan, Juan\|Espin, Eloi\|Rosello, Jose\|Majo, Joaquin\|Benavente, Sergi\|Armengol, Manel\|de Torres, I
PMID:	15816107

332.
Journal:	Curr Opin Oncol. 2005 May;17(3):212-7.
Title:	Monoclonal antibodies targeting epidermal growth factor receptor and vascular endothelial growth factor with a focus on head and neck tumors.
Author:	Caponigro, Francesco\|Formato, Roberta\|Caraglia, Michele\|Normanno, Nicola\|Iaffaioli, Rosario Vincenzo
PMID:	15818163

333.
Journal:	Drugs Today (Barc). 2005 Feb;41(2):107-27.
Title:	Cetuximab: an epidermal growth factor receptor chemeric human-murine monoclonal antibody.
Author:	Harding, Joanne\|Burtness, Barbara
PMID:	15821783

334.
Journal:	Med Hypotheses. 2005;64(6):1162-5.
Title:	Selenium supplementation may increase the efficacy of cetuximab in metastatic colorectal cancer patients.
Author:	Altundag, Kadri\|Silay, Yavuz S\|Altundag, Ozden\|Yigitbasi, Orhan G\|Gundeslioglu, Ozlem\|Gunduz, Mehmet
PMID:	15823708

335.
Journal:	Cancer Cell. 2005 Apr;7(4):287-8.
Title:	EGF receptor inhibition: attacks on multiple fronts.
Author:	Hubbard, Stevan R
PMID:	15837615

336.
Journal:	Curr Oncol Rep. 2005 May;7(3):167-72.
Title:	First-line therapy for advanced colorectal cancer.
Author:	de Gramont, Aimery\|Tournigand, Christophe\|Louvet, Christophe\|Maindrault-Goebel, Frederique\|Andre, Thierry
PMID:	15847706

337.
Journal:	Lancet Oncol. 2005 May;6(5):279-86.
Title:	Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study.
Author:	Moroni, Mauro\|Veronese, Silvio\|Benvenuti, Silvia\|Marrapese, Giovanna\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Gambacorta, Marcello\|Siena, Salvatore\|Bardelli, Alberto
PMID:	15863375

338.
Journal:	Cancer Res. 2005 May 1;65(9):3716-25.
Title:	Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.
Author:	Yokoi, Kenji\|Thaker, Premal H\|Yazici, Sertac\|Rebhun, Robert R\|Nam, Do-Hyun\|He, Junqin\|Kim, Sun-Jin\|Abbruzzese, James L\|Hamilton, Stanley R\|Fidler, Isaiah J
PMID:	15867367

339.
Journal:	Ann Oncol. 2005 Sep;16(9):1557-8; author reply 1558-9. Epub 2005 May 3.
Title:	Relevance of EGFR expression in colorectal cancer.
Author:	Alliot, C
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340.
Journal:	Br J Cancer. 2005 May 23;92(10):1846-9.
Title:	A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer.
Author:	Veronese, M L\|Sun, W\|Giantonio, B\|Berlin, J\|Shults, J\|Davis, L\|Haller, D G\|O'Dwyer, P J
PMID:	15870719

341.
Journal:	Clin Colorectal Cancer. 2005 Apr;5 Suppl 1:S19-27.
Title:	Epidermal growth factor receptor as a target for chemotherapy.
Author:	Vallbohmer, Daniel\|Lenz, Heinz-Josef
PMID:	15871762

342.
Journal:	Ann Oncol. 2005 Sep;16(9):1557. Epub 2005 May 4.
Title:	Impact of EGFR expression on colorectal cancer patient prognosis and survival: a response.
Author:	Repetto, L\|Gianni, W\|Agliano, A M\|Gazzaniga, P
PMID:	15871994

343.
Journal:	Cancer. 2005 Jun 15;103(12):2435-46.
Title:	Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma.
Author:	Venook, Alan P
PMID:	15880563

344.
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Title:	Reorganization of ErbB family and cell survival signaling after Knock-down of ErbB2 in colon cancer cells.
Author:	Hu, Yi Peter\|Venkateswarlu, Srinivas\|Sergina, Natalia\|Howell, Gillian\|St Clair, Patricia\|Humphrey, Lisa E\|Li, Wenhui\|Hauser, Jennie\|Zborowska, Elizabeth\|Willson, James K V\|Brattain, Michael G
PMID:	15888451

345.
Journal:	Curr Cancer Drug Targets. 2005 May;5(3):171-93.
Title:	Molecularly targeted therapy for gastrointestinal cancer.
Author:	Wiedmann, Marcus W\|Caca, Karel
PMID:	15892618

346.
Journal:	Cancer Res. 2005 May 15;65(10):4253-60.
Title:	HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.
Author:	Hirata, Akira\|Hosoi, Fumihito\|Miyagawa, Miho\|Ueda, Shu-ichi\|Naito, Seiji\|Fujii, Teruhiko\|Kuwano, Michihiko\|Ono, Mayumi
PMID:	15899817

347.
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348.
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Title:	Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues.
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PMID:	15908435

349.
Journal:	Cancer Lett. 2005 Jul 8;225(1):61-74. Epub 2004 Dec 25.
Title:	Interferon-alpha promotes the anti-proliferative effect of Erlotinib (OSI-774) on human colon cancer cell lines.
Author:	Yang, Jia-Lin\|Qu, Xian-Jun\|Russell, Pamela J\|Goldstein, David
PMID:	15922858

350.
Journal:	Ann Oncol. 2005 May;16 Suppl 4:iv74-79.
Title:	Concurrent EGFr and Cox-2 expression in colorectal cancer: proliferation impact and tumour spreading.
Author:	Ceccarelli, C\|Piazzi, G\|Paterini, P\|Pantaleo, M A\|Taffurelli, M\|Santini, D\|Martinelli, G N\|Biasco, G
PMID:	15923435

351.
Journal:	Expert Rev Mol Diagn. 2005 May;5(3):353-75.
Title:	Molecular markers that predict response to colon cancer therapy.
Author:	Ahmed, Farid E
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352.
Journal:	Cancer Chemother Pharmacol. 2005 Nov;56(5):455-64. Epub 2005 Jun 10.
Title:	Correlation of pharmacokinetics with the antitumor activity of Cetuximab in nude mice bearing the GEO human colon carcinoma xenograft.
Author:	Luo, F R\|Yang, Z\|Dong, H\|Camuso, A\|McGlinchey, K\|Fager, K\|Flefleh, C\|Kan, D\|Inigo, I\|Castaneda, S\|Rose, W C\|Kramer, R A\|Wild, R\|Lee, F Y
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353.
Journal:	BMC Cancer. 2005 Jun 20;5:62.
Title:	Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer.
Author:	Azria, David\|Bibeau, Frederic\|Barbier, Nicolas\|Zouhair, Abderrahim\|Lemanski, Claire\|Rouanet, Philippe\|Ychou, Marc\|Senesse, Pierre\|Ozsahin, Mahmut\|Pelegrin, Andre\|Dubois, Jean-Bernard\|Thezenas, Simon
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354.
Journal:	Ann Oncol. 2005 Sep;16(9):1503-7. Epub 2005 Jun 24.
Title:	Epidermal growth factor receptor (EGFR) status in primary colorectal tumors correlates with EGFR expression in related metastatic sites: biological and clinical implications.
Author:	Italiano, A\|Saint-Paul, M-C\|Caroli-Bosc, F-X\|Francois, E\|Bourgeon, A\|Benchimol, D\|Gugenheim, J\|Michiels, J-F
PMID:	15980160

355.
Journal:	Cancer Res. 2005 Jul 1;65(13):5848-56.
Title:	Synergy of epidermal growth factor receptor kinase inhibitor AG1478 and ErbB2 kinase inhibitor AG879 in human colon carcinoma cells is associated with induction of apoptosis.
Author:	Zhou, Yunfei\|Brattain, Michael G
PMID:	15994962

356.
Journal:	Int J Oncol. 2005 Aug;27(2):317-25.
Title:	Coexpression, prognostic significance and predictive value of EGFR, EGFRvIII and phosphorylated EGFR in colorectal cancer.
Author:	Cunningham, Matthew P\|Essapen, Sharadah\|Thomas, Hilary\|Green, Margaret\|Lovell, David P\|Topham, Clare\|Marks, Christopher\|Modjtahedi, Helmout
PMID:	16010411

357.
Journal:	Ann Oncol. 2005 Nov;16(11):1848-9. Epub 2005 Jul 12.
Title:	Somatic mutation of EGFR catalytic domain and treatment with gefitinib in colorectal cancer.
Author:	Moroni, M\|Sartore-Bianchi, A\|Benvenuti, S\|Artale, S\|Bardelli, A\|Siena, S
PMID:	16012179

358.
Journal:	Cancer Res. 2005 Jul 15;65(14):6275-81.
Title:	Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner.
Author:	Krysan, Kostyantyn\|Reckamp, Karen L\|Dalwadi, Harnisha\|Sharma, Sherven\|Rozengurt, Enrique\|Dohadwala, Mariam\|Dubinett, Steven M
PMID:	16024629

359.
Journal:	J Pathol. 2005 Oct;207(2):156-63.
Title:	Up-regulated expression of ADAM17 in human colon carcinoma: co-expression with EGFR in neoplastic and endothelial cells.
Author:	Blanchot-Jossic, Frederique\|Jarry, Anne\|Masson, Damien\|Bach-Ngohou, Kalyane\|Paineau, Jacques\|Denis, Marc G\|Laboisse, Christian L\|Mosnier, Jean-Francois
PMID:	16041691

360.
Journal:	Biochem Biophys Res Commun. 2005 Sep 2;334(3):947-53.
Title:	EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.
Author:	Shimizu, Masahito\|Deguchi, Atsuko\|Hara, Yukihiko\|Moriwaki, Hisataka\|Weinstein, I Bernard
PMID:	16053920

361.
Journal:	Neoplasma. 2005;52(4):338-43.
Title:	Epidermal growth factor receptor--its expression and copy numbers of EGFR gene in patients with head and neck squamous cell carcinomas.
Author:	Mrhalova, M\|Plzak, J\|Betka, J\|Kodet, R
PMID:	16059652

362.
Journal:	Clin Cancer Res. 2005 Aug 1;11(15):5558-65.
Title:	Prediction of active drug plasma concentrations achieved in cancer patients by pharmacodynamic biomarkers identified from the geo human colon carcinoma xenograft model.
Author:	Luo, Feng R\|Yang, Zheng\|Dong, Huijin\|Camuso, Amy\|McGlinchey, Kelly\|Fager, Krista\|Flefleh, Christine\|Kan, David\|Inigo, Ivan\|Castaneda, Stephen\|Wong, Tai W\|Kramer, Robert A\|Wild, Robert\|Lee, Francis Y
PMID:	16061873

363.
Journal:	Acta Oncol. 2005;44(3):203-17.
Title:	Targeted drugs in metastatic colorectal cancer with special emphasis on guidelines for the use of bevacizumab and cetuximab: an Acta Oncologica expert report.
Author:	Nygren, Peter\|Sorbye, Halfdan\|Osterlund, Pia\|Pfeiffer, Per
PMID:	16076691

364.
Journal:	Clin Colorectal Cancer. 2005 Jul;5(2):124-31.
Title:	Gene polymorphisms of epidermal growth factor receptor and its downstream effector, interleukin-8, predict oxaliplatin efficacy in patients with advanced colorectal cancer.
Author:	Zhang, Wu\|Stoehlmacher, Jan\|Park, David J\|Yang, Dongyun\|Borchard, Erin\|Gil, Ji\|Tsao-Wei, Denice D\|Yun, Jim\|Gordon, Michael\|Press, Oliver A\|Rhodes, Katrin\|Groshen, Susan\|Lenz, Heinz-Josef
PMID:	16098254

365.
Journal:	J Natl Cancer Inst. 2005 Aug 17;97(16):1221-4.
Title:	Cetuximab therapy and symptomatic hypomagnesemia.
Author:	Schrag, Deborah\|Chung, Ki Young\|Flombaum, Carlos\|Saltz, Leonard
PMID:	16106027

366.
Journal:	Endocr Relat Cancer. 2005 Jul;12 Suppl 1:S159-71.
Title:	Intrinsic and acquired resistance to EGFR inhibitors in human cancer therapy.
Author:	Bianco, Roberto\|Troiani, Teresa\|Tortora, Giampaolo\|Ciardiello, Fortunato
PMID:	16113092

367.
Journal:	Eur J Cancer. 2005 Oct;41(15):2338-46. Epub 2005 Aug 22.
Title:	Gefitinib-responsive EGFR-positive colorectal cancers have different proteome profiles from non-responsive cell lines.
Author:	Loeffler-Ragg, Judith\|Skvortsov, Sergej\|Sarg, Bettina\|Skvortsova, Ira\|Witsch-Baumgartner, Martina\|Mueller, Doris\|Lindner, Herbert\|Zwierzina, Heinz
PMID:	16115757

368.
Journal:	Clin Ther. 2005 Jun;27(6):684-94.
Title:	Cetuximab: an epidermal growth factor receptor monoclonal antibody for the treatment of colorectal cancer.
Author:	Wong, Siu-Fun
PMID:	16117976

369.
Journal:	World J Gastroenterol. 2005 Sep 7;11(33):5142-50.
Title:	Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid decreases ErbB3 expression in HT-29 human colon cancer cells.
Author:	Cho, Han Jin\|Kim, Woo Kyoung\|Jung, Jae In\|Kim, Eun Ji\|Lim, Soon Sung\|Kwon, Dae Young\|Park, Jung Han Yoon
PMID:	16127743

370.
Journal:	Oncology. 2005;69(3):224-38. Epub 2005 Sep 1.
Title:	Interferon-alpha promotes the anti-proliferative effect of gefitinib (ZD 1839) on human colon cancer cell lines.
Author:	Yang, Jia-Lin\|Qu, Xian-Jun\|Russell, Pamela J\|Goldstein, David
PMID:	16138001

371.
Journal:	J Carcinog. 2005 Sep 2;4:16.
Title:	Sulindac metabolites inhibit epidermal growth factor receptor activation and expression.
Author:	Pangburn, Heather A\|Kraus, Hanna\|Ahnen, Dennis J\|Rice, Pamela L
PMID:	16138927

372.
Journal:	Biochem Pharmacol. 2005 Oct 1;70(7):1035-47.
Title:	Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors.
Author:	Cheng, Kunrong\|Raufman, Jean-Pierre
PMID:	16139803

373.
Journal:	Dermatol Online J. 2005 Aug 1;11(2):22.
Title:	Unusually large colon cancer cutaneous and subcutaneous metastases occurring in resection scars.
Author:	Alexandrescu, Doru T\|Vaillant, Juan\|Yahr, Laura J\|Kelemen, Pond\|Wiernik, Peter H
PMID:	16150230

374.
Journal:	Apoptosis. 2005 Oct;10(5):1175-86.
Title:	Irreversible pan-ErbB tyrosine kinase inhibitor CI-1033 induces caspase-independent apoptosis in colorectal cancer DiFi cell line.
Author:	Skvortsov, S\|Skvortsova, I\|Sarg, B\|Loeffler-Ragg, J\|Lindner, H\|Lukas, P\|Tabernero, J\|Zwierzina, H
PMID:	16151650

375.
Journal:	Clin Cancer Res. 2005 Sep 15;11(18):6650-6.
Title:	Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.
Author:	Ogino, Shuji\|Meyerhardt, Jeffrey A\|Cantor, Mami\|Brahmandam, Mohan\|Clark, Jeffrey W\|Namgyal, Chungdak\|Kawasaki, Takako\|Kinsella, Kate\|Michelini, Ann L\|Enzinger, Peter C\|Kulke, Matthew H\|Ryan, David P\|Loda, Massimo\|Fuchs, Charles S
PMID:	16166444

376.
Journal:	Lung Cancer. 2005 Dec;50(3):375-84. Epub 2005 Sep 30.
Title:	Epidermal growth factor receptor gene mutation in non-small cell lung cancer using highly sensitive and fast TaqMan PCR assay.
Author:	Endo, Katsuhiko\|Konishi, Akimitsu\|Sasaki, Hidefumi\|Takada, Minoru\|Tanaka, Hisaichi\|Okumura, Meinoshin\|Kawahara, Masaaki\|Sugiura, Hironori\|Kuwabara, Yoshiyuki\|Fukai, Ichiro\|Matsumura, Akihide\|Yano, Motoki\|Kobayashi, Yoshihiro\|Mizuno, Kotaro\|Haneda, Hiroshi
PMID:	16199108

377.
Journal:	Oncol Rep. 2005 Nov;14(5):1199-202.
Title:	Tenascin C and epidermal growth factor receptor as markers of circulating tumoral cells in bladder and colon cancer.
Author:	Gazzaniga, Paola\|Nofroni, Italo\|Gandini, Orietta\|Silvestri, Ida\|Frati, Luigi\|Agliano, Anna Maria\|Gradilone, Angela
PMID:	16211285

378.
Journal:	Surgery. 2005 Sep;138(3):415-21.
Title:	Ligand-dependent activation of the epidermal growth factor receptor by secondary bile acids in polarizing colon cancer cells.
Author:	Merchant, Nipun B\|Rogers, Christopher M\|Trivedi, Bakula\|Morrow, Jason\|Coffey, Robert J
PMID:	16213893

379.
Journal:	Anticancer Drugs. 2005 Nov;16(10):1099-108.
Title:	The epidermal growth factor receptor tyrosine kinase inhibitor gefitinib sensitizes colon cancer cells to irinotecan.
Author:	Braun, Ada Henrike\|Stark, Katrin\|Dirsch, Olaf\|Hilger, Ralf Axel\|Seeber, Siegfried\|Vanhoefer, Udo
PMID:	16222152

380.
Journal:	World J Gastroenterol. 2005 Sep 28;11(36):5638-43.
Title:	Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells.
Author:	Shida, Dai\|Kitayama, Joji\|Yamaguchi, Hironori\|Yamashita, Hiroharu\|Mori, Ken\|Watanabe, Toshiaki\|Nagawa, Hirokazu
PMID:	16237757

381.
Journal:	Clin Cancer Res. 2005 Oct 15;11(20):7480-9.
Title:	Epidermal growth factor receptor activity determines response of colorectal cancer cells to gefitinib alone and in combination with chemotherapy.
Author:	Van Schaeybroeck, Sandra\|Karaiskou-McCaul, Anthi\|Kelly, Donal\|Longley, Daniel\|Galligan, Leeona\|Van Cutsem, Eric\|Johnston, Patrick
PMID:	16243822

382.
Journal:	Nat Clin Pract Oncol. 2005 Jun;2(6):284-5.
Title:	Does epidermal growth factor receptor status predict activity of cetuximab in colorectal cancer patients?
Author:	Baselga, Jose
PMID:	16264980

383.
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Author:	Des Guetz, G
PMID:	16292207

384.
Journal:	Am J Clin Oncol. 2005 Dec;28(6):560-4.
Title:	Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer.
Author:	Watwe, Veena\|Javle, Milind\|Lawrence, David\|Groth, Jeffrey\|Iyer, Renuka\|El-Hajjar, Dany\|Geradts, Joseph
PMID:	16317264

385.
Journal:	Cancer Biol Ther. 2005 Dec;4(12):1381-6. Epub 2005 Dec 31.
Title:	Assessment of Epidermal Growth Factor Receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis.
Author:	Messersmith, Wells\|Oppenheimer, Darin\|Peralba, Josep\|Sebastiani, Valeria\|Amador, Maria\|Jimeno, Antonio\|Embuscado, Erlinda\|Hidalgo, Manuel\|Iacobuzio-Donahue, Christine
PMID:	16319527

386.
Journal:	Cancer Nurs. 2005 Nov-Dec;28(6):481-6.
Title:	Gefitinib (Iressa, ZD1839) and tyrosine kinase inhibitors: the wave of the future in cancer therapy.
Author:	Penne, Kara\|Bohlin, Cindy\|Schneider, Susan\|Allen, Deborah
PMID:	16330971

387.
Journal:	Clin Colorectal Cancer. 2005 Nov;5 Suppl 2:S60-1.
Title:	Introduction: Emerging therapies with epidermal growth factor receptor-targeted agents in colorectal cancer.
Author:	Chu, Edward
PMID:	16336750

388.
Journal:	Clin Colorectal Cancer. 2005 Nov;5 Suppl 2:S62-70.
Title:	Current status of small-molecule tyrosine kinase inhibitors targeting epidermal growth factor receptor in colorectal cancer.
Author:	Kuo, Timothy\|Fisher, George A
PMID:	16336751

389.
Journal:	Clin Colorectal Cancer. 2005 Nov;5 Suppl 2:S71-80.
Title:	Overview of monoclonal antibodies and small molecules targeting the epidermal growth factor receptor pathway in colorectal cancer.
Author:	Snyder, Lorraine C\|Astsaturov, Igor\|Weiner, Louis M
PMID:	16336752

390.
Journal:	Clin Colorectal Cancer. 2005 Nov;5 Suppl 2:S81-8.
Title:	Recent data with anti-epidermal growth factor receptor antibodies and irinotecan in colon cancer.
Author:	Chua, Yu Jo\|Cunningham, David
PMID:	16336753

391.
Journal:	Clin Colorectal Cancer. 2005 Nov;5 Suppl 2:S98-100.
Title:	Epidermal growth factor receptor-negative colorectal cancer: is there truly such an entity?
Author:	Saltz, Leonard
PMID:	16336755

392.
Journal:	Semin Oncol. 2005 Dec;32(6 Suppl 8):7-10.
Title:	Molecular mechanisms and targeting of colorectal cancer.
Author:	Vanhoefer, Udo
PMID:	16360005

393.
Journal:	J Clin Oncol. 2005 Dec 20;23(36):9265-74.
Title:	Randomized phase II trial of the clinical and biological effects of two dose levels of gefitinib in patients with recurrent colorectal adenocarcinoma.
Author:	Rothenberg, Mace L\|LaFleur, Bonnie\|Levy, Donna E\|Washington, Mary Kay\|Morgan-Meadows, Sherry L\|Ramanathan, Ramesh K\|Berlin, Jordan D\|Benson, Al B 3rd\|Coffey, Robert J
PMID:	16361624

394.
Journal:	Bull Cancer. 2005 Aug;92(Spec no):S3-4.
Title:	EGFR/VEGF signalling pathway in colorectal cancer: the way we are!
Author:	Spano, Jean-Philippe\|Milano, Gerard\|Baselga, Jose
PMID:	16387661

395.
Journal:	Bull Cancer. 2005 Aug;92(Spec no):S5-11.
Title:	[EGFR expression in colorectal cancer and role in tumorigenesis].
Author:	Penault-Llorca, Frederique\|Bibeau, Frederic\|Arnould, Laurent\|Bralet, Marie-Pierre\|Rochaix, Philippe\|Sabourin, Jean-Christophe
PMID:	16387663

396.
Journal:	Bull Cancer. 2005 Aug;92(Spec no):S13-6.
Title:	[Prognostic value of EGFR in colorectal cancer].
Author:	Vignot, Stephane\|Spano, Jean-Philippe
PMID:	16387664

397.
Journal:	Bull Cancer. 2005 Aug;92(Spec no):S17-20.
Title:	[Pharmacological skills for targeting EGFR and VEGF].
Author:	Milano, Gerard
PMID:	16387665

398.
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Title:	[Targeting the epidermal growth factor receptor in colorectal cancer: clinical results].
Author:	Adenis, Antoine\|Hebbar, Mohamed
PMID:	16387666

399.
Journal:	Bull Cancer. 2005 Aug;92(Spec no):S37-43.
Title:	[Targeted therapies and radiotherapy in colorectal cancer].
Author:	Azria, David\|Magne, Nicolas
PMID:	16387668

400.
Journal:	Semin Oncol. 2005 Dec;32(6 Suppl 9):S55-8.
Title:	The role of cetuximab in the therapy of previously treated advanced colorectal cancer.
Author:	Chong, Geoff\|Cunningham, David
PMID:	16399433

401.
Journal:	Semin Oncol. 2005 Dec;32(6 Suppl 9):S59-62.
Title:	Correlation between the response to cetuximab alone or in combination with irinotecan and the activated/phosphorylated epidermal growth factor receptor in metastatic colorectal cancer.
Author:	Personeni, Nicola\|Hendlisz, Alain\|Gallez, Julien\|Galdon, Maria Gomez\|Larsimont, Denis\|Van Laethem, Jean-Luc\|Nagy, Nathalie\|Barette, Martine\|Paesmans, Marianne\|Cardoso, Fatima\|Bleiberg, Harry
PMID:	16399434

402.
Journal:	Prescrire Int. 2005 Dec;14(80):215-7.
Title:	Cetuximab: new drug. Metastatic colorectal cancer: an inappropriate evaluation.
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PMID:	16400742

403.
Journal:	J Exp Ther Oncol. 2005;5(1):69-78.
Title:	EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
Author:	Shimizu, Masahito\|Deguchi, Atsuko\|Joe, Andrew K\|Mckoy, Judith F\|Moriwaki, Hisataka\|Weinstein, I Bernard
PMID:	16416603

404.
Journal:	Pathologica. 2005 Aug;97(4):180-2.
Title:	[Prognostic/predictive role of epidermal growth factor receptor (EGFR) in colorectal carcinoma].
Author:	Rossi, S
PMID:	16440643

405.
Journal:	Future Oncol. 2005 Apr;1(2):173-81.
Title:	Cetuximab in the treatment of colorectal cancer.
Author:	Ciardiello, Fortunato\|De Vita, Ferdinando\|Orditura, Michele\|Comunale, Daniela\|Galizia, Gennaro
PMID:	16555987

406.
Journal:	Future Oncol. 2005 Apr;1(2):221-34.
Title:	Epidermal growth factor receptor inhibitors in cancer treatment.
Author:	Ciardiello, Fortunato
PMID:	16555994

407.
Journal:	Hautarzt. 2006 Aug;57(8):701-4.
Title:	[Follicular drug reaction from cetuximab: a common side effect in the treatment of metastatic colon carcinoma].
Author:	Braun-Falco, M\|Holtmann, C\|Lordick, F\|Ring, J
PMID:	15991047

408.
Journal:	Cell Death Differ. 2006 Feb;13(2):202-11.
Title:	Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells.
Author:	Monteleone, G\|Franchi, L\|Fina, D\|Caruso, R\|Vavassori, P\|Monteleone, I\|Calabrese, E\|Naccari, G C\|Bellinvia, S\|Testi, R\|Pallone, F
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409.
Journal:	Oncogene. 2006 Jan 12;25(2):278-87.
Title:	Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1.
Author:	Chen, A\|Xu, J\|Johnson, A C
PMID:	16170359

410.
Journal:	Int J Cancer. 2006 Mar 15;118(6):1426-9.
Title:	Somatic mutations of the ERBB4 kinase domain in human cancers.
Author:	Soung, Young Hwa\|Lee, Jong Woo\|Kim, Su Young\|Wang, Young Pil\|Jo, Keon Hyun\|Moon, Seok Whan\|Park, Won Sang\|Nam, Suk Woo\|Lee, Jung Young\|Yoo, Nam Jin\|Lee, Sug Hyung
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411.
Journal:	Exp Mol Pathol. 2006 Apr;80(2):165-70. Epub 2005 Oct 3.
Title:	Expression of caveolin-1 is correlated with Akt-1 in colorectal cancer tissues.
Author:	Kim, Hyun-Ah\|Kim, Kwang-Ho\|Lee, Ryung-Ah
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412.
Journal:	Am J Physiol Cell Physiol. 2006 Feb;290(2):C592-600. Epub 2005 Oct 5.
Title:	Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner.
Author:	O'Reilly, Susan M\|Leonard, Martin O\|Kieran, Niamh\|Comerford, Katrina M\|Cummins, Eoin\|Pouliot, Marc\|Lee, Sean B\|Taylor, Cormac T
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413.
Journal:	J Surg Res. 2006 May;132(1):56-61. Epub 2005 Nov 14.
Title:	Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.
Author:	Mori, Ken\|Kitayama, Joji\|Shida, Dai\|Yamashita, Hiroharu\|Watanabe, Toshiaki\|Nagawa, Hirokazu
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414.
Journal:	Ann Oncol. 2006 Mar;17(3):450-6. Epub 2005 Nov 22.
Title:	Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma.
Author:	Folprecht, G\|Lutz, M P\|Schoffski, P\|Seufferlein, T\|Nolting, A\|Pollert, P\|Kohne, C-H
PMID:	16303861

415.
Journal:	Cancer Chemother Pharmacol. 2006 Jun;57(6):709-18. Epub 2005 Dec 1.
Title:	In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR.
Author:	Balin-Gauthier, Diane\|Delord, Jean-Pierre\|Rochaix, Philippe\|Mallard, Valerie\|Thomas, Fabienne\|Hennebelle, Isabelle\|Bugat, Roland\|Canal, Pierre\|Allal, Cuider
PMID:	16320055

416.
Journal:	J Surg Oncol. 2006 Jan 1;93(1):44-6.
Title:	The epidermal growth factor receptor gene sequence is highly conserved in primary gastric cancers.
Author:	Mimori, Koshi\|Nagahara, Hisashi\|Sudo, Tomoya\|Ishii, Hideshi\|Yamashita, Keishi\|Barnard, Graham F\|Mori, Masaki
PMID:	16353180

417.
Journal:	Exp Cell Res. 2006 Feb 15;312(4):387-400.
Title:	Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.
Author:	Carothers, Adelaide M\|Javid, Sara H\|Moran, Amy E\|Hunt, Daniel H\|Redston, Mark\|Bertagnolli, Monica M
PMID:	16368433

418.
Journal:	Int J Oncol. 2006 Feb;28(2):329-35.
Title:	Coexpression of the IGF-IR, EGFR and HER-2 is common in colorectal cancer patients.
Author:	Cunningham, Matthew P\|Essapen, Sharadah\|Thomas, Hilary\|Green, Margaret\|Lovell, David P\|Topham, Clare\|Marks, Christopher\|Modjtahedi, Helmout
PMID:	16391786

419.
Journal:	Clin Cancer Res. 2006 Jan 1;12(1):57-61.
Title:	Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas.
Author:	Lee, Jong Woo\|Soung, Young Hwa\|Seo, Si Hyung\|Kim, Su Young\|Park, Cho Hyun\|Wang, Young Pil\|Park, Kyeongmee\|Nam, Suk Woo\|Park, Won Sang\|Kim, Sang Ho\|Lee, Jung Young\|Yoo, Nam Jin\|Lee, Sug Hyung
PMID:	16397024

420.
Journal:	Clin Cancer Res. 2006 Jan 1;12(1):183-90.
Title:	Anti-CD3 x anti-epidermal growth factor receptor (EGFR) bispecific antibody redirects T-cell cytolytic activity to EGFR-positive cancers in vitro and in an animal model.
Author:	Reusch, Ursula\|Sundaram, Magesh\|Davol, Pamela A\|Olson, Sarah D\|Davis, James B\|Demel, Kurt\|Nissim, Julie\|Rathore, Ritesh\|Liu, Paul Y\|Lum, Lawrence G
PMID:	16397041

421.
Journal:	Cancer Res. 2006 Jan 1;66(1):404-11.
Title:	Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis.
Author:	Zhou, Yunfei\|Li, Song\|Hu, Yi P\|Wang, Jing\|Hauser, Jennie\|Conway, Alexis N\|Vinci, Michelle A\|Humphrey, Lisa\|Zborowska, Elizabeth\|Willson, James K V\|Brattain, Michael G
PMID:	16397255

422.
Journal:	Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1492-7. Epub 2006 Jan 23.
Title:	Role of beta-arrestin 1 in the metastatic progression of colorectal cancer.
Author:	Buchanan, F Gregory\|Gorden, D Lee\|Matta, Pranathi\|Shi, Qiong\|Matrisian, Lynn M\|DuBois, Raymond N
PMID:	16432186

423.
Journal:	J Clin Oncol. 2006 Feb 1;24(4):656-62.
Title:	Increased toxicity with gefitinib, capecitabine, and radiation therapy in pancreatic and rectal cancer: phase I trial results.
Author:	Czito, Brian G\|Willett, Christopher G\|Bendell, Johanna C\|Morse, Michael A\|Tyler, Douglas S\|Fernando, Nishan H\|Mantyh, Christopher R\|Blobe, Gerard C\|Honeycutt, Wanda\|Yu, Daohai\|Clary, Bryan M\|Pappas, Theodore N\|Ludwig, Kirk A\|Hurwitz, Herbert I
PMID:	16446337

424.
Journal:	Cancer Invest. 2006 Feb;24(1):98-105.
Title:	Target practice: figuring out which, when, and why to use systemic therapies for metastatic colon cancer.
Author:	Holen, Kyle D
PMID:	16466998

425.
Journal:	Bull Cancer. 2006 Feb 1;93 Suppl 1:S11-5.
Title:	[Reflexion on a good strategy of use of oxaliplatine with 5-fluorouracil and its derivatives in patients with advanced colorectal cancer].
Author:	Tournigand, Christophe\|de Gramont, Aimery
PMID:	16483941

426.
Journal:	Biochem Biophys Res Commun. 2006 Apr 7;342(2):585-8. Epub 2006 Feb 10.
Title:	9-Hydroxystearic acid interferes with EGF signalling in a human colon adenocarcinoma.
Author:	Calonghi, Natalia\|Pagnotta, Eleonora\|Parolin, Carola\|Tognoli, Cristina\|Boga, Carla\|Masotti, Lanfranco
PMID:	16487928

427.
Journal:	Br J Cancer. 2006 Mar 27;94(6):792-7.
Title:	Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial.
Author:	Vincenzi, B\|Santini, D\|Rabitti, C\|Coppola, R\|Beomonte Zobel, B\|Trodella, L\|Tonini, G
PMID:	16508634

428.
Journal:	Cancer Res. 2006 Mar 1;66(5):2683-90.
Title:	FHIT is up-regulated by inflammatory stimuli and inhibits prostaglandin E2-mediated cancer progression.
Author:	Mimori, Koshi\|Ishii, Hideshi\|Nagahara, Hisashi\|Sudo, Tomoya\|Yamashita, Keishi\|Inoue, Hiroshi\|Barnard, Graham F\|Mori, Masaki
PMID:	16510588

429.
Journal:	Ann Oncol. 2006 Jun;17(6):962-7. Epub 2006 Mar 8.
Title:	EGFR in colorectal cancer: more than a simple receptor.
Author:	Francoual, M\|Etienne-Grimaldi, M-C\|Formento, J-L\|Benchimol, D\|Bourgeon, A\|Chazal, M\|Letoublon, C\|Andre, T\|Gilly, N\|Delpero, J-R\|Lasser, P\|Spano, J-P\|Milano, G
PMID:	16524971

430.
Journal:	Cancer. 2006 Apr 15;106(8):1857-62.
Title:	Comparison of two antibodies for immunohistochemical evaluation of epidermal growth factor receptor expression in colorectal carcinomas, adenomas, and normal mucosa.
Author:	Bhargava, Rohit\|Chen, Beiyun\|Klimstra, David S\|Saltz, Leonard B\|Hedvat, Cyrus\|Tang, Laura H\|Gerald, William\|Teruya-Feldstein, Julie\|Paty, Philip B\|Qin, Jing\|Shia, Jinru
PMID:	16532444

431.
Journal:	Expert Opin Ther Targets. 2006 Apr;10(2):281-7.
Title:	Anti-EGFR strategies as an incremental step for the treatment of colorectal cancer patients: moving from scientific evidence to clinical practice.
Author:	Scartozzi, Mario\|Pierantoni, Chiara\|Berardi, Rossana\|Squadroni, Michela\|Cascinu, Stefano
PMID:	16548776

432.
Journal:	Oncology (Williston Park). 2006 Feb;20(2):153-61; discussion 162, 166, 169
Title:	Targeting the epidermal growth factor receptor. Trials in head and neck and lung cancer.
Author:	Saba, Nabil F\|Khuri, Fadlo R\|Shin, Dong M
PMID:	16562649

433.
Journal:	J Biol Chem. 2006 May 26;281(21):14700-10. Epub 2006 Mar 30.
Title:	Attenuation of peroxisome proliferator-activated receptor gamma (PPARgamma) mediates gastrin-stimulated colorectal cancer cell proliferation.
Author:	Chang, Albert J\|Song, Diane H\|Wolfe, M Michael
PMID:	16574647

434.
Journal:	Oncol Rep. 2006 May;15(5):1205-10.
Title:	Mutations of the epidermal growth factor receptor gene in gastrointestinal tract tumor cell lines.
Author:	Kimura, Toshimoto\|Maesawa, Chihaya\|Ikeda, Kenichiro\|Wakabayashi, Go\|Masuda, Tomoyuki
PMID:	16596188

435.
Journal:	Ann Surg Oncol. 2006 Jun;13(6):823-35. Epub 2006 Apr 18.
Title:	Prognostic significance of epidermal growth factor receptor expression in colon cancer patients undergoing curative surgery.
Author:	Galizia, Gennaro\|Lieto, Eva\|Ferraraccio, Francesca\|De Vita, Ferdinando\|Castellano, Paolo\|Orditura, Michele\|Imperatore, Vincenzo\|La Mura, Anna\|La Manna, Giovanni\|Pinto, Margherita\|Catalano, Giuseppe\|Pignatelli, Carlo\|Ciardiello, Fortunato
PMID:	16614884

436.
Journal:	Int J Radiat Oncol Biol Phys. 2006 May 1;65(1):246-54.
Title:	Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers.
Author:	Goethals, Laurence\|Debucquoy, Annelies\|Perneel, Christiaan\|Geboes, Karel\|Ectors, Nadine\|De Schutter, Harlinde\|Penninckx, Freddy\|McBride, William H\|Begg, Adrian C\|Haustermans, Karin M
PMID:	16618579

437.
Journal:	Cancer Res. 2006 Apr 15;66(8):3992-5.
Title:	KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.
Author:	Lievre, Astrid\|Bachet, Jean-Baptiste\|Le Corre, Delphine\|Boige, Valerie\|Landi, Bruno\|Emile, Jean-Francois\|Cote, Jean-Francois\|Tomasic, Gorana\|Penna, Christophe\|Ducreux, Michel\|Rougier, Philippe\|Penault-Llorca, Frederique\|Laurent-Puig, Pierre
PMID:	16618717

438.
Journal:	Anticancer Res. 2006 Mar-Apr;26(2A):1029-37.
Title:	EGF receptor-related protein (ERRP) inhibits invasion of colon cancer cells and tubule formation by endothelial cells in vitro.
Author:	Rishi, Arun K\|Parikh, Rakesh\|Wali, Anil\|Durko, Lukasz\|Zhang, Liyue\|Yu, Yingjie\|Majumdar, Adhip P N
PMID:	16619503

439.
Journal:	J Clin Oncol. 2006 Apr 20;24(12):1957; author reply 1957-8.
Title:	New issues on cetuximab mechanism of action in epidermal growth factor receptor-negative colorectal cancer: the role of vascular endothelial growth factor.
Author:	Vincenzi, Bruno\|Santini, Daniele\|Tonini, Giuseppe
PMID:	16622275

440.
Journal:	Anal Quant Cytol Histol. 2006 Apr;28(2):61-8.
Title:	Epidermal growth factor receptor: a promising therapeutic target for colorectal cancer.
Author:	Scartozzi, Mario\|Pierantoni, Chiara\|Berardi, Rossana\|Antognoli, Stefania\|Bearzi, Italo\|Cascinu, Stefano
PMID:	16637508

441.
Journal:	Am J Health Syst Pharm. 2006 May 1;63(9 Suppl 2):S12-7.
Title:	Individualizing chemotherapeutic treatment of colorectal cancer.
Author:	Crews, Kristine R
PMID:	16641252

442.
Journal:	Hum Mol Genet. 2006 Apr 15;15 Spec No 1:R89-93.
Title:	Pharmacogenomics: from bedside to clinical practice.
Author:	Marsh, Sharon\|McLeod, Howard L
PMID:	16651374

443.
Journal:	J Drugs Dermatol. 2006 Apr;5(4):368-9.
Title:	Epidermal growth factor receptor (EGFR) inhibitor associated skin eruption.
Author:	Seiverling, Elizabeth V\|Fernanadez, Emmy M\|Adams, David
PMID:	16673807

444.
Journal:	Oncology. 2006;70(3):161-7. Epub 2006 May 3.
Title:	Targeting the epidermal growth factor receptor in colorectal cancer: advances and controversies.
Author:	Italiano, Antoine
PMID:	16675911

445.
Journal:	Onkologie. 2006 May;29(5):198-200. Epub 2006 May 3.
Title:	Tissue microarray analysis of EGFR gene amplification and gain in Bulgarian patients with colorectal cancer.
Author:	Petrova, Darinka\|Jankova, Renata\|Yosifova, Adelina\|Tzenova, Vasselina\|Dimova, Ivanka\|Toncheva, Draga
PMID:	16679780

446.
Journal:	J Cell Physiol. 2006 Aug;208(2):344-53.
Title:	Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases.
Author:	Morelli, Maria Pia\|Cascone, Tina\|Troiani, Teresa\|Tuccillo, Concetta\|Bianco, Roberto\|Normanno, Nicola\|Romano, Marco\|Veneziani, Bianca Maria\|Fontanini, Gabriella\|Eckhardt, S Gail\|De Pacido, Sabino\|Tortora, Giampaolo\|Ciardiello, Fortunato
PMID:	16688779

447.
Journal:	Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):705-12.
Title:	Epidermal growth factor receptor as a prognostic factor in locally advanced rectal-cancer patients treated with preoperative chemoradiation.
Author:	Li, Shengjin\|Kim, Jae-Sung\|Kim, Jin-Man\|Cho, Moon-June\|Yoon, Wan-Hee\|Song, Kyu-Sang\|Yeo, Seung-Gu\|Kim, Jun-Sang
PMID:	16690221

448.
Journal:	Oncology (Williston Park). 2006 Apr;20(5 Suppl 2):15-25.
Title:	Anti-EGFR therapies: clinical experience in colorectal, lung, and head and neck cancers.
Author:	Vokes, Everett E\|Chu, Edward
PMID:	16736979

449.
Journal:	J Soc Integr Oncol. 2006 Winter;4(1):21-6.
Title:	Down-regulation of prostaglandin E2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines.
Author:	Lev-Ari, Shahar\|Maimon, Yair\|Strier, Ludmila\|Kazanov, Dina\|Arber, Nadir
PMID:	16737669

450.
Journal:	Cancer Res. 2006 Jun 1;66(11):5656-64.
Title:	Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci.
Author:	Cohen, Greg\|Mustafi, Reba\|Chumsangsri, Anusara\|Little, Nathaniel\|Nathanson, Jeff\|Cerda, Sonia\|Jagadeeswaran, Sujatha\|Dougherty, Urszula\|Joseph, Loren\|Hart, John\|Yerian, Lisa\|Tretiakova, Maria\|Yuan, Weihua\|Obara, Piotr\|Khare, Sharad\|Sinicrope, Frank A\|Fich
PMID:	16740703

451.
Journal:	Int J Radiat Oncol Biol Phys. 2006 Oct 1;66(2):500-4.
Title:	Prediction of response to chemoradiation in rectal cancer by a gene polymorphism in the epidermal growth factor receptor promoter region.
Author:	Spindler, Karen-Lise Garm\|Nielsen, Jens Nederby\|Lindebjerg, Jan\|Brandslund, Ivan\|Jakobsen, Anders
PMID:	16757132

452.
Journal:	Ann Oncol. 2006 Dec;17(12):1850-1. Epub 2006 Jun 9.
Title:	EGFR expression in colon cancer: a break in the clouds.
Author:	Etienne-Grimaldi, M-C\|Cayre, A\|Penault-Llorca, F\|Francoual, M\|Formento, J-L\|Benchimol, D\|Bourgeon, A\|Milano, G
PMID:	16766589

453.
Journal:	Expert Opin Drug Saf. 2006 Jul;5(4):553-66.
Title:	Incidence and management of bevacizumab-related toxicities in colorectal cancer.
Author:	Saif, M Wasif\|Mehra, Ranee
PMID:	16774493

454.
Journal:	J Drug Target. 2006 May;14(4):215-23.
Title:	EGFR-targeted immunoliposomes derived from the monoclonal antibody EMD72000 mediate specific and efficient drug delivery to a variety of colorectal cancer cells.
Author:	Mamot, Christoph\|Ritschard, Reto\|Kung, Willy\|Park, John W\|Herrmann, Richard\|Rochlitz, Christoph F
PMID:	16777680

455.
Journal:	Pharmacogenet Genomics. 2006 Jul;16(7):475-83.
Title:	Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab.
Author:	Zhang, Wu\|Gordon, Michael\|Press, Oliver A\|Rhodes, Katrin\|Vallbohmer, Daniel\|Yang, Dong Yun\|Park, David\|Fazzone, William\|Schultheis, Anne\|Sherrod, Andy E\|Iqbal, Syma\|Groshen, Susan\|Lenz, Heinz-Josef
PMID:	16788380

456.
Journal:	Clin Colorectal Cancer. 2006 May;6(1):13.
Title:	Panitumumab: a new anti-EGFR antibody for the treatment of advanced colorectal cancer.
Author:	Chu, Edward
PMID:	16796785

457.
Journal:	Cancer J. 2006 May-Jun;12(3):229-36.
Title:	Clinicopathologic significance of EGFR and Her-2/neu in colorectal adenocarcinomas.
Author:	Kountourakis, Panteleimon\|Pavlakis, Kitty\|Psyrri, Amanda\|Rontogianni, Dimitra\|Xiros, Nikolaos\|Patsouris, Efstratios\|Pectasides, Dimitrios\|Economopoulos, Theofanis
PMID:	16803682

458.
Journal:	Cell Stress Chaperones. 2006 Summer;11(2):135-47.
Title:	Stress-induced phosphorylation of caveolin-1 and p38, and down-regulation of EGFr and ERK by the dietary lectin jacalin in two human carcinoma cell lines.
Author:	Sahasrabuddhe, Anagh A\|Ahmed, Neesar\|Krishnasastry, M V
PMID:	16817319

459.
Journal:	Cancer Res. 2006 Jul 1;66(13):6649-56.
Title:	Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression.
Author:	Mann, Jason R\|Backlund, Michael G\|Buchanan, F Gregory\|Daikoku, Taki\|Holla, Vijaykumar R\|Rosenberg, Daniel W\|Dey, Sudhansu K\|DuBois, Raymond N
PMID:	16818638

460.
Journal:	Clin Cancer Res. 2006 Jul 1;12(13):4036-42.
Title:	Humanization of the bispecific epidermal growth factor receptor x CD3 diabody and its efficacy as a potential clinical reagent.
Author:	Asano, Ryutaro\|Sone, Yukiko\|Makabe, Koki\|Tsumoto, Kouhei\|Hayashi, Hiroki\|Katayose, Yu\|Unno, Michiaki\|Kudo, Toshio\|Kumagai, Izumi
PMID:	16818703

461.
Journal:	Br J Cancer. 2006 Jul 17;95(2):172-80. Epub 2006 Jul 4.
Title:	Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells.
Author:	Jones, H E\|Gee, J M W\|Barrow, D\|Tonge, D\|Holloway, B\|Nicholson, R I
PMID:	16819546

462.
Journal:	Zhonghua Wai Ke Za Zhi. 2006 Jun 1;44(11):765-9.
Title:	[Double sites short hairpin RNAs targeting epidermal growth factor receptor to promote colon cancer cells apoptosis and enhance 5-fluorouracil chemotherapy effect].
Author:	Wu, Xiang-bai\|Tao, Kai-xiong\|Wang, Guo-bin\|Tian, Yuan\|Zhang, Jing-hui\|Chen, Dao-da
PMID:	16836928

463.
Journal:	Int J Radiat Oncol Biol Phys. 2006 Sep 1;66(1):195-200.
Title:	Epidermal growth factor receptor as a predictor of tumor downstaging in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy.
Author:	Kim, Jun-Sang\|Kim, Jin-Man\|Li, Shengjin\|Yoon, Wan-Hee\|Song, Kyu-Sang\|Kim, Ki-Hwan\|Yeo, Seung-Gu\|Nam, Ji Sook\|Cho, Moon-June
PMID:	16839708

464.
Journal:	Pharmacogenet Genomics. 2006 Aug;16(8):555-63.
Title:	Gene expression in tumor-adjacent normal tissue is associated with recurrence in patients with rectal cancer treated with adjuvant chemoradiation.
Author:	Schneider, Sylke\|Park, David J\|Yang, Dongyun\|El-Khoueiry, Anthony\|Sherrod, Andy\|Groshen, Susan\|Streeter, Oscar\|Iqbal, Syma\|Danenberg, Kathleen D\|Lenz, Heinz-Josef
PMID:	16847424

465.
Journal:	Cancer Res. 2006 Jul 15;66(14):6955-63.
Title:	Protein kinase C alpha but not PKCzeta suppresses intestinal tumor formation in ApcMin/+ mice.
Author:	Oster, Henrik\|Leitges, Michael
PMID:	16849539

466.
Journal:	Clin Cancer Res. 2006 Jul 15;12(14 Pt 2):4426s-4431s.
Title:	Strategies to enhance epidermal growth factor inhibition: targeting the mevalonate pathway.
Author:	Dimitroulakos, Jim\|Lorimer, Ian A\|Goss, Glenwood
PMID:	16857822

467.
Journal:	Cancer Res. 2006 Aug 1;66(15):7708-15.
Title:	Responses of human colorectal tumor cells to treatment with the anti-epidermal growth factor receptor monoclonal antibody ICR62 used alone and in combination with the EGFR tyrosine kinase inhibitor gefitinib.
Author:	Cunningham, Matthew P\|Thomas, Hilary\|Fan, Zhen\|Modjtahedi, Helmout
PMID:	16885373

468.
Journal:	Semin Oncol. 2006 Aug;33(4):369-85.
Title:	Epidermal growth factor receptor targeting in cancer.
Author:	Mendelsohn, John\|Baselga, Jose
PMID:	16890793

469.
Journal:	Mol Cancer Ther. 2006 Jul;5(7):1883-94.
Title:	Sequence-dependent inhibition of human colon cancer cell growth and of prosurvival pathways by oxaliplatin in combination with ZD6474 (Zactima), an inhibitor of VEGFR and EGFR tyrosine kinases.
Author:	Troiani, Teresa\|Lockerbie, Owen\|Morrow, Mark\|Ciardiello, Fortunato\|Eckhardt, S Gail
PMID:	16891475

470.
Journal:	Int J Cancer. 2006 Nov 15;119(10):2435-42.
Title:	Molecular determinants of irinotecan efficacy.
Author:	Vallbohmer, Daniel\|Iqbal, Syma\|Yang, Dong Yun\|Rhodes, Katrin E\|Zhang, Wu\|Gordon, Michael\|Fazzone, William\|Schultheis, Anne M\|Sherrod, Andy E\|Danenberg, Kathleen D\|Lenz, Heinz-Josef
PMID:	16894565

471.
Journal:	Drugs. 2006;66(11):1441-63.
Title:	Targeting the epidermal growth factor receptor in the treatment of colorectal cancer: state of the art.
Author:	Diasio, Robert B\|Fourie, Jeanne
PMID:	16906777

472.
Journal:	Cancer. 2006 Sep 15;107(6):1207-18.
Title:	Clinical implications of the mechanism of epidermal growth factor receptor inhibitors.
Author:	Marshall, John
PMID:	16909423

473.
Journal:	Future Oncol. 2006 Aug;2(4):449-57.
Title:	Cetuximab in squamous cell carcinoma of the head and neck.
Author:	Hitt, Ricardo\|Martin, Patricia\|Hidalgo, Manuel
PMID:	16922611

474.
Journal:	Anticancer Drugs. 2006 Aug;17(7):855-7.
Title:	Lack of usefulness of epidermal growth factor receptor expression determination for cetuximab therapy in patients with colorectal cancer.
Author:	Hebbar, Mohamed\|Wacrenier, Agnes\|Desauw, Christophe\|Romano, Olivier\|Cattan, Stephane\|Triboulet, Jean-Pierre\|Pruvot, Francois-Rene
PMID:	16926635

475.
Journal:	Mol Cancer Ther. 2006 Aug;5(8):2051-9.
Title:	Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity.
Author:	Buck, Elizabeth\|Eyzaguirre, Alexandra\|Haley, John D\|Gibson, Neil W\|Cagnoni, Pablo\|Iwata, Kenneth K
PMID:	16928826

476.
Journal:	World J Gastroenterol. 2006 Aug 28;12(32):5140-7.
Title:	Prolonged exposure of colon cancer cells to the epidermal growth factor receptor inhibitor gefitinib (Iressa(TM)) and to the antiangiogenic agent ZD6474: Cytotoxic and biomolecular effects.
Author:	Azzariti, Amalia\|Porcelli, Letizia\|Xu, Jian-Ming\|Simone, Grazia Maria\|Paradiso, Angelo
PMID:	16937523

477.
Journal:	Clin Colorectal Cancer. 2006 Jul;6(2):118-24.
Title:	Role of panitumumab in the management of metastatic colorectal cancer.
Author:	Saif, Mohammad Wasif\|Cohenuram, Michael
PMID:	16945167

478.
Journal:	Gastroenterol Clin North Am. 2006 Sep;35(3):713-27.
Title:	Systemic treatment of patients who have colorectal cancer and inflammatory bowel disease.
Author:	Goessling, Wolfram\|Mayer, Robert J
PMID:	16952747

479.
Journal:	Actas Dermosifiliogr. 2006 Jun;97(5):296-310.
Title:	[Epidermal growth factor receptor inhibitors side effects].
Author:	Guhl, Guillermo\|Gonzalez-de Arriba, Ana\|Dauden, Esteban
PMID:	16956561

480.
Journal:	World J Gastroenterol. 2006 Sep 21;12(35):5635-43.
Title:	Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer.
Author:	Hopfner, Michael\|Sutter, Andreas P\|Huether, Alexander\|Baradari, Viola\|Scherubl, Hans
PMID:	17007015

481.
Journal:	Int J Oncol. 2006 Nov;29(5):1159-65.
Title:	Epidermal growth factor receptor analyses in colorectal cancer: a comparison of methods.
Author:	Spindler, Karen-Lise Garm\|Lindebjerg, Jan\|Nielsen, Jens Nederby\|Olsen, Dorte Aalund\|Bisgard, Claus\|Brandslund, Ivan\|Jakobsen, Anders
PMID:	17016647

482.
Journal:	Clin Colorectal Cancer. 2006 Sep;6(3):208-13.
Title:	Phase I study of gefitinib plus FOLFIRI in previously untreated patients with metastatic colorectal cancer.
Author:	Wolpin, Brian M\|Clark, Jeffrey W\|Meyerhardt, Jeffrey A\|Earle, Craig C\|Ryan, David P\|Enzinger, Peter C\|Zhu, Andrew X\|Blaszkowsky, Lawrence\|Battu, Subha\|Fuchs, Charles S
PMID:	17026790

483.
Journal:	Clin Colorectal Cancer. 2006 Sep;6(3):214-8.
Title:	Epidermal growth factor receptor and epidermal growth factor receptor variant III gene expression in metastatic colorectal cancer.
Author:	Azuma, Mizutomo\|Danenberg, Kathleen D\|Iqbal, Syma\|El-Khoueiry, Anthony\|Zhang, Wu\|Yang, Dongyun\|Koizumi, Wasaburo\|Saigenji, Katsunori\|Danenberg, Peter V\|Lenz, Heinz-Josef
PMID:	17026791

484.
Journal:	Oncologist. 2006 Oct;11(9):1010-7.
Title:	Challenges in the use of epidermal growth factor receptor inhibitors in colorectal cancer.
Author:	Van Cutsem, Eric
PMID:	17030643

485.
Journal:	Oncologist. 2006 Oct;11(9):1018-24.
Title:	Novel therapeutic developments other than EGFR and VEGF inhibition in colorectal cancer.
Author:	Wilson, Richard H
PMID:	17030644

486.
Journal:	Nutr Cancer. 2006;55(2):185-94.
Title:	Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells.
Author:	Reddy, Sudha\|Rishi, Arun K\|Xu, Hu\|Levi, Edi\|Sarkar, Fazlul H\|Majumdar, Adhip P N
PMID:	17044774

487.
Journal:	Biochim Biophys Acta. 2006 Dec;1766(2):217-29. Epub 2006 Sep 12.
Title:	Pharmacogenomics of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.
Author:	Jimeno, Antonio\|Hidalgo, Manuel
PMID:	17045403

488.
Journal:	Expert Opin Biol Ther. 2006 Nov;6(11):1175-92.
Title:	Recent developments in colorectal cancer treatment by monoclonal antibodies.
Author:	Arsene, Dominique\|Galais, Marie-Pierre\|Bouhier-Leporrier, Karine\|Reimund, Jean-Marie
PMID:	17049015

489.
Journal:	Expert Opin Biol Ther. 2006 Nov;6(11):1229-35.
Title:	Panitumumab in colon cancer: a review and summary of ongoing trials.
Author:	Wainberg, Zev\|Hecht, J Randolph
PMID:	17049019

490.
Journal:	J Clin Oncol. 2006 Oct 20;24(30):4914-21.
Title:	Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines.
Author:	Lenz, Heinz-Josef\|Van Cutsem, Eric\|Khambata-Ford, Shirin\|Mayer, Robert J\|Gold, Philip\|Stella, Philip\|Mirtsching, Barry\|Cohn, Allen L\|Pippas, Andrew W\|Azarnia, Nozar\|Tsuchihashi, Zenta\|Mauro, David J\|Rowinsky, Eric K
PMID:	17050875

491.
Journal:	J Surg Res. 2006 Dec;136(2):227-31. Epub 2006 Oct 23.
Title:	Compensatory increases in Her-2/neu activation in response to EGFR tyrosine kinase inhibition in colon cancer cell lines.
Author:	Learn, Peter A\|Krishnegowda, Naveen\|Talamantez, Jose\|Kahlenberg, Morton S
PMID:	17059835

492.
Journal:	Eur Surg Res. 2006;38(6):540-4. Epub 2006 Nov 3.
Title:	Does the EGFR and VEGF expression predict the prognosis in colon cancer?
Author:	Doger, Furuzan Kacar\|Meteoglu, Ibrahim\|Tuncyurek, Pars\|Okyay, Pinar\|Cevikel, Hakan
PMID:	17085940

493.
Journal:	Br J Cancer. 2006 Dec 4;95(11):1525-8. Epub 2006 Oct 31.
Title:	Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa.
Author:	Piazzi, G\|Paterini, P\|Ceccarelli, C\|Pantaleo, M A\|Biasco, G
PMID:	17088913

494.
Journal:	Oncol Rep. 2006 Dec;16(6):1173-9.
Title:	Is there an immunohistochemical technique definitively valid in epidermal growth factor receptor assessment?
Author:	Penault-Llorca, Frederique\|Cayre, Anne\|Arnould, Laurent\|Bibeau, Frederic\|Bralet, Marie-Pierre\|Rochaix, Philippe\|Savary, Jacqueline\|Sabourin, Jean-Christophe
PMID:	17089034

495.
Journal:	Drugs. 2006;66(15):2005-14; discussion 2015-6.
Title:	Panitumumab: in the treatment of metastatic colorectal cancer.
Author:	Hoy, Sheridan M\|Wagstaff, Antona J
PMID:	17100412

496.
Journal:	Ned Tijdschr Geneeskd. 2006 Nov 18;150(46):2555-9.
Title:	[Long-term beneficial effects of cetuximab in a woman with metastasised rectal carcinoma without expression of the epidermal growth factor receptor].
Author:	Kroep, J R\|Gelderblom, H\|Collen, A F S\|Nortier, J W R
PMID:	17152334

497.
Journal:	Drugs Today (Barc). 2006 Nov;42(11):711-9.
Title:	Panitumumab.
Author:	Chua, Yu Jo\|Cunningham, David
PMID:	17171190

498.
Journal:	Clin Cancer Res. 2006 Dec 15;12(24):7222-31.
Title:	Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway.
Author:	Rosell, Rafael\|Taron, Miquel\|Reguart, Noemi\|Isla, Dolores\|Moran, Teresa
PMID:	17189393

499.
Journal:	Anticancer Res. 2006 Nov-Dec;26(6C):4889-93.
Title:	Lack of the type III epidermal growth factor receptor mutation in colorectal cancer.
Author:	Spindler, Karen-Lise Garm\|Olsen, Dorte Aalund\|Nielsen, Jens Nederby\|Brandslund, Ivan\|Poulsen, Hans Skovgaard\|Villingshoj, Mette\|Jakobsen, Anders
PMID:	17214357

500.
Journal:	Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):578-82.
Title:	[Experimental study of effect of epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in combination with irinotecan].
Author:	Xu, Jian-ming\|Li, Yue-min\|Wang, Yan\|Zhao, Chuan-hua\|Yuan, Shou-jun\|Yang, Wu-wei\|Li, Zhi-qiang\|Han, Yu\|Azzariti, Amalia\|Paradiso, Angelo
PMID:	17236550

501.
Journal:	Clin Colorectal Cancer. 2006 Nov;6(4):305-11.
Title:	Gene expression levels of epidermal growth factor receptor, survivin, and vascular endothelial growth factor as molecular markers of lymph node involvement in patients with locally advanced rectal cancer.
Author:	Yang, Dongyun\|Schneider, Sylke\|Azuma, Mizutomo\|Iqbal, Syma\|El-Khoueiry, Anthony\|Groshen, Susan\|Agafitei, Dana\|Danenberg, Kathleen D\|Danenberg, Peter V\|Ladner, Robert D\|Lenz, Heinz-Josef
PMID:	17241515

502.
Journal:	Dis Markers. 2006;22(5-6):309-16.
Title:	Higher expression of epidermal growth factor receptor is associated with extracellular matrix metalloprotease inducer in colorectal adenocarcinoma: tissue microarray analysis of immunostaining score with clinicopathological parameters.
Author:	Jin, Jong-Shiaw\|Wu, Chi-Ying\|Lin, Yeh-Feng\|Wang, Jia-Yi\|Yu, Cheng-Ping\|Sheu, Lai-Fa\|Chiang, Hung\|Tsai, Wen-Chiuan\|Lee, Wei-Hwa
PMID:	17264401

503.
Journal:	Oncology (Williston Park). 2006 Dec;20(14 Suppl 10):21-8.
Title:	Recognizing and managing toxicities of molecular targeted therapies for colorectal cancer.
Author:	Grothey, Axel
PMID:	17354514

504.
Journal:	Ann Med. 2006;38(8):545-51.
Title:	Novel approaches to treatment of advanced colorectal cancer with anti-EGFR monoclonal antibodies.
Author:	Zhang, Wu\|Gordon, Michael\|Lenz, Heinz-Josef
PMID:	17438669

505.
Journal:	Rev Recent Clin Trials. 2006 May;1(2):113-8.
Title:	Monoclonal antibodies against epidermal growth factor receptor in advanced colorectal carcinoma: clinical efficacy and markers of sensitivity.
Author:	Carcereny, Enric\|Maurel, Joan
PMID:	18473962

506.
Journal:	Drug Discov Today Dis Mech. 2006 Winter;3(4):439.
Title:	New insights into the molecular pathogenesis of colorectal cancer.
Author:	Hung, Kenneth E\|Chung, Daniel C
PMID:	20151020

507.
Journal:	J Clin Pathol. 2007 Jul;60(7):768-72. Epub 2006 Aug 1.
Title:	HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer.
Author:	Al-Kuraya, Khawla\|Novotny, Hedvika\|Bavi, Prashant\|Siraj, Abdul K\|Uddin, Shahab\|Ezzat, Adnan\|Sanea, Nasser Al\|Al-Dayel, Fouad\|Al-Mana, Hadeel\|Sheikh, Salwa S\|Mirlacher, Martina\|Tapia, Coya\|Simon, Ronald\|Sauter, Guido\|Terracciano, Luigi\|Tornillo, Luigi
PMID:	16882699

508.
Journal:	Cancer Chemother Pharmacol. 2007 Apr;59(5):651-9. Epub 2006 Aug 26.
Title:	Antitumor activity of HER1/EGFR tyrosine kinase inhibitor erlotinib, alone and in combination with CPT-11 (irinotecan) in human colorectal cancer xenograft models.
Author:	Chen, Jianping\|Smith, Melissa\|Kolinsky, Kenneth\|Adames, Violeta\|Mehta, Nila\|Fritzky, Luke\|Rashed, Mohammad\|Wheeldon, Eric\|Linn, Michael\|Higgins, Brian
PMID:	16937104

509.
Journal:	Oncogene. 2007 Mar 29;26(14):2006-16. Epub 2006 Sep 25.
Title:	Heparin-binding EGF-like growth factor is an early response gene to chemotherapy and contributes to chemotherapy resistance.
Author:	Wang, F\|Liu, R\|Lee, S W\|Sloss, C M\|Couget, J\|Cusack, J C
PMID:	17001310

510.
Journal:	Jpn J Clin Oncol. 2007 Jan;37(1):44-8.
Title:	Prospective study of positron emission tomography for evaluation of the activity of lapatinib, a dual inhibitor of the ErbB1 and ErbB2 tyrosine kinases, in patients with advanced tumors.
Author:	Kawada, Kenji\|Murakami, Koji\|Sato, Takashi\|Kojima, Yoshiki\|Ebi, Hiromichi\|Mukai, Hirofumi\|Tahara, Makoto\|Shimokata, Kaoru\|Minami, Hironobu
PMID:	17060407

511.
Journal:	Hautarzt. 2007 Jul;58(7):615-8.
Title:	[Therapy of severe cetuximab-induced acneiform eruptions with oral retinoid, topical antibiotic and topical corticosteroid].
Author:	Wollenberg, A\|Moosmann, N\|Kroth, J\|Heinemann, V\|Klein, E
PMID:	17146641

512.
Journal:	Virchows Arch. 2007 Feb;450(2):151-9.
Title:	Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations.
Author:	Schmitz, K J\|Wohlschlaeger, J\|Alakus, H\|Bohr, J\|Stauder, M A\|Worm, K\|Winde, G\|Schmid, K W\|Baba, H A
PMID:	17149612

513.
Journal:	J Surg Res. 2007 Mar;138(1):56-63. Epub 2006 Dec 12.
Title:	Combining siRNAs at two different sites in the EGFR to suppress its expression, induce apoptosis, and enhance 5-fluorouracil sensitivity of colon cancer cells.
Author:	Wu, Xiangbai\|Deng, Yongzhi\|Wang, Guobin\|Tao, Kaixiong
PMID:	17169374

514.
Journal:	Int J Radiat Oncol Biol Phys. 2007 Jan 1;67(1):318.
Title:	Epidermal growth factor receptor and rectal cancer: in regard to Kim et al. (Int J Radiat Oncol Biol Phys 2006;66:195-200).
Author:	Bibeau, Frederic\|Sennesse, Pierre\|Boissiere, Florence\|Azria, David
PMID:	17189081

515.
Journal:	Cancer Lett. 2007 Jun 28;251(2):237-46. Epub 2006 Dec 26.
Title:	Anti-EGFR and ErbB-2 antibodies attenuate cyclooxygenase-2 expression and cooperatively inhibit survival of human colon cancer cells.
Author:	Half, Elizabeth\|Sun, Yunjie\|Sinicrope, Frank A
PMID:	17189670

516.
Journal:	J Pharmacol Exp Ther. 2007 Apr;321(1):84-97.
Title:	Regulation of oxidant-induced intestinal permeability by metalloprotease-dependent epidermal growth factor receptor signaling.
Author:	Forsyth, C B\|Banan, A\|Farhadi, A\|Fields, J Z\|Tang, Y\|Shaikh, M\|Zhang, L J\|Engen, P A\|Keshavarzian, A
PMID:	17220428

517.
Journal:	Histopathology. 2007 Jan;50(2):210-6.
Title:	Immunohistochemical variability of epidermal growth factor receptor (EGFR) in liver metastases from colonic carcinomas.
Author:	Bralet, M-P\|Paule, B\|Falissard, B\|Adam, R\|Guettier, C
PMID:	17222249

518.
Journal:	Biochem Pharmacol. 2007 Apr 1;73(7):1001-12. Epub 2006 Dec 10.
Title:	Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line.
Author:	Cheng, Kunrong\|Xie, Guofeng\|Raufman, Jean-Pierre
PMID:	17222808

519.
Journal:	Biochem Biophys Res Commun. 2007 Mar 9;354(2):409-13. Epub 2007 Jan 9.
Title:	A new EGFR inhibitor induces apoptosis in colon cancer cells.
Author:	Calonghi, N\|Pagnotta, E\|Parolin, C\|Mangano, C\|Bolognesi, M L\|Melchiorre, C\|Masotti, L
PMID:	17227671

520.
Journal:	Int J Cancer. 2007 Apr 15;120(8):1652-6.
Title:	Neurotensin stimulates expression of early growth response gene-1 and EGF receptor through MAP kinase activation in human colonic epithelial cells.
Author:	Zhao, Dezheng\|Zhan, Yanai\|Zeng, Huiyan\|Koon, Hon Wai\|Moyer, Mary P\|Pothoulakis, Charalabos
PMID:	17230532

521.
Journal:	Mol Nutr Food Res. 2007 Feb;51(2):192-200.
Title:	The epidermal growth factor receptor and human topoisomerases represent potential cellular targets of oligomeric procyanidins.
Author:	Fridrich, Diana\|Kern, Melanie\|Fritz, Jessica\|Pahlke, Gudrun\|Kohler, Nils\|Winterhalter, Peter\|Marko, Doris
PMID:	17230588

522.
Journal:	Cancer Res. 2007 Jan 15;67(2):665-73.
Title:	A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo.
Author:	Rajput, Ashwani\|Koterba, Alan P\|Kreisberg, Jeffrey I\|Foster, Jason M\|Willson, James K V\|Brattain, Michael G
PMID:	17234777

523.
Journal:	Cancer Res. 2007 Jan 15;67(2):827-35.
Title:	Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis.
Author:	Fichera, Alessandro\|Little, Nathaniel\|Jagadeeswaran, Sujatha\|Dougherty, Urszula\|Sehdev, Amikar\|Mustafi, Reba\|Cerda, Sonia\|Yuan, Weihua\|Khare, Sharad\|Tretiakova, Maria\|Gong, Can\|Tallerico, Michael\|Cohen, Greg\|Joseph, Loren\|Hart, John\|Turner, Jerrold R\|Biss
PMID:	17234795

524.
Journal:	Expert Opin Biol Ther. 2007 Feb;7(2):257-68.
Title:	Lapatinib: a dual inhibitor of EGFR and HER2 tyrosine kinase activity.
Author:	Montemurro, Filippo\|Valabrega, Giorgio\|Aglietta, Massimo
PMID:	17250463

525.
Journal:	Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):523-31.
Title:	Phase 1b dose escalation study of erlotinib in combination with infusional 5-Fluorouracil, leucovorin, and oxaliplatin in patients with advanced solid tumors.
Author:	Hanauske, Axel-R\|Cassidy, Jim\|Sastre, Javier\|Bolling, Claus\|Jones, Robert J\|Rakhit, Ashok\|Fettner, Scott\|Brennscheidt, Ulrich\|Feyereislova, Andrea\|Diaz-Rubio, Eduardo
PMID:	17255274

526.
Journal:	Gastroenterology. 2007 Feb;132(2):645-53.
Title:	A simple method for the routine detection of somatic quantitative genetic alterations in colorectal cancer.
Author:	Killian, Audrey\|Di Fiore, Frederic\|Le Pessot, Florence\|Blanchard, France\|Lamy, Aude\|Raux, Gregory\|Flaman, Jean-Michel\|Paillot, Bernard\|Michel, Pierre\|Sabourin, Jean-Christophe\|Tuech, Jean-Jacques\|Michot, Francis\|Kerckaert, Jean-Pierre\|Sesboue, Richard\|Fre
PMID:	17258723

527.
Journal:	Virchows Arch. 2007 Mar;450(3):321-8. Epub 2007 Jan 30.
Title:	Co-expression of EGF receptor, TGFalpha and S6 kinase is significantly associated with colorectal carcinomas with distant metastases at diagnosis.
Author:	Tampellini, Marco\|Longo, Marina\|Cappia, Susanna\|Bacillo, Elisa\|Alabiso, Irene\|Volante, Marco\|Dogliotti, Luigi\|Papotti, Mauro
PMID:	17265080

528.
Journal:	Clin Cancer Res. 2007 Feb 1;13(3):986-93.
Title:	A phase 1 escalating single-dose and weekly fixed-dose study of cetuximab: pharmacokinetic and pharmacodynamic rationale for dosing.
Author:	Fracasso, Paula M\|Burris, Howard 3rd\|Arquette, Matthew A\|Govindan, Ramaswamy\|Gao, Feng\|Wright, Lisa P\|Goodner, Sherry A\|Greco, F Anthony\|Jones, Suzanne F\|Willcut, Noel\|Chodkiewicz, Catherine\|Pathak, Amit\|Springett, Gregory M\|Simon, George R\|Sullivan, Dani
PMID:	17289894

529.
Journal:	J Gastroenterol Hepatol. 2007 Mar;22(3):436-43.
Title:	Cimetidine inhibits epidermal growth factor-induced cell signaling.
Author:	Fujikawa, Tatsuya\|Shiraha, Hidenori\|Nakanishi, Yutaka\|Takaoka, Nobuyuki\|Ueda, Naoki\|Suzuki, Mayumi\|Shiratori, Yasushi
PMID:	17295779

530.
Journal:	Mol Cancer Ther. 2007 Feb;6(2):532-41.
Title:	Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition.
Author:	Buck, Elizabeth\|Eyzaguirre, Alexandra\|Barr, Sharon\|Thompson, Stuart\|Sennello, Regina\|Young, David\|Iwata, Kenneth K\|Gibson, Neil W\|Cagnoni, Pablo\|Haley, John D
PMID:	17308052

531.
Journal:	Br J Cancer. 2007 Mar 12;96(5):793-800. Epub 2007 Feb 20.
Title:	A simple and reproducible scoring system for EGFR in colorectal cancer: application to prognosis and prediction of response to preoperative brachytherapy.
Author:	Zlobec, I\|Vuong, T\|Hayashi, S\|Haegert, D\|Tornillo, L\|Terracciano, L\|Lugli, A\|Jass, J
PMID:	17311026

532.
Journal:	Clin Colorectal Cancer. 2007 Jan;6(5):357-61.
Title:	Targeted therapy in colorectal cancer.
Author:	Wadler, Scott
PMID:	17311700

533.
Journal:	BJU Int. 2007 Jun;99(6):1539-45. Epub 2007 Mar 6.
Title:	Erlotinib (OSI-774)-induced inhibition of transitional cell carcinoma of bladder cell line growth is enhanced by interferon-alpha.
Author:	Yang, Jia-Lin\|Qu, Xian-Jun\|Hayes, Vanessa M\|Brenner, Phillip C\|Russell, Pamela J\|Goldstein, David
PMID:	17346275

534.
Journal:	Ann Pharmacother. 2007 Apr;41(4):606-13. Epub 2007 Mar 13.
Title:	Panitumumab: a fully human monoclonal antibody with activity in metastatic colorectal cancer.
Author:	Saadeh, Claire E\|Lee, H Stephen
PMID:	17355997

535.
Journal:	Cancer Res. 2007 Mar 15;67(6):2643-8.
Title:	Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.
Author:	Benvenuti, Silvia\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Zanon, Carlo\|Moroni, Mauro\|Veronese, Silvio\|Siena, Salvatore\|Bardelli, Alberto
PMID:	17363584

536.
Journal:	Ann Surg Oncol. 2007 Jul;14(7):2169-70.
Title:	Epidermal growth factor receptor and prognosis in colon cancer: a crack in the wall?
Author:	Ferrara, Gerardo\|Palombi, Natalia\|Di Blasi, Arturo
PMID:	17375355

537.
Journal:	Mol Nutr Food Res. 2007 May;51(5):594-601.
Title:	Apple polyphenols diminish the phosphorylation of the epidermal growth factor receptor in HT29 colon carcinoma cells.
Author:	Fridrich, Diana\|Kern, Melanie\|Pahlke, Gudrun\|Volz, Nadine\|Will, Frank\|Dietrich, Helmut\|Marko, Doris
PMID:	17427262

538.
Journal:	Int J Radiat Oncol Biol Phys. 2007 Aug 1;68(5):1455-61.
Title:	Prognostic and predictive value of baseline and posttreatment molecular marker expression in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy.
Author:	Bertolini, Federica\|Bengala, Carmelo\|Losi, Luisa\|Pagano, Maria\|Iachetta, Francesco\|Dealis, Cristina\|Jovic, Gordana\|Depenni, Roberta\|Zironi, Sandra\|Falchi, Anna Maria\|Luppi, Gabriele\|Conte, Pier Franco
PMID:	17445998

539.
Journal:	Eur J Nucl Med Mol Imaging. 2007 Sep;34(9):1510-1.
Title:	PET detection of epidermal growth factor receptor in colorectal cancer: a real predictor of response to cetuximab treatment?
Author:	Pantaleo, M A\|Fanti, S\|Lollini, P L\|Boschi, S\|Biasco, G
PMID:	17447062

540.
Journal:	Neoplasia. 2007 Apr;9(4):341-8.
Title:	Oncogenic K-Ras signals through epidermal growth factor receptor and wild-type H-Ras to promote radiation survival in pancreatic and colorectal carcinoma cells.
Author:	Cengel, Keith A\|Voong, K Rahn\|Chandrasekaran, Sanjay\|Maggiorella, Laurence\|Brunner, Thomas B\|Stanbridge, Eric\|Kao, Gary D\|McKenna, W Gillies\|Bernhard, Eric J
PMID:	17460778

541.
Journal:	Lancet Oncol. 2007 May;8(5):387-94.
Title:	Magnesium wasting associated with epidermal-growth-factor receptor-targeting antibodies in colorectal cancer: a prospective study.
Author:	Tejpar, Sabine\|Piessevaux, Hubert\|Claes, Kathleen\|Piront, Patricia\|Hoenderop, Joost G J\|Verslype, Chris\|Van Cutsem, Eric
PMID:	17466895

542.
Journal:	J Clin Oncol. 2007 May 1;25(13):1658-64.
Title:	Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer.
Author:	Van Cutsem, Eric\|Peeters, Marc\|Siena, Salvatore\|Humblet, Yves\|Hendlisz, Alain\|Neyns, Bart\|Canon, Jean-Luc\|Van Laethem, Jean-Luc\|Maurel, Joan\|Richardson, Gary\|Wolf, Michael\|Amado, Rafael G
PMID:	17470858

543.
Journal:	Differentiation. 2007 Nov;75(9):809-18. Epub 2007 May 19.
Title:	Quantitative imaging of apoptosis commitment in colorectal tumor cells.
Author:	Keese, Michael\|Offterdinger, Martin\|Tischer, Christian\|Girod, Andreas\|Lommerse, Piet H M\|Yagublu, Vugar\|Magdeburg, Richard\|Bastiaens, Philippe I H
PMID:	17511782

544.
Journal:	Int J Biol Markers. 2007 Jan-Mar;22(1 Suppl 4):S53-61.
Title:	Clinical management of cutaneous toxicity of anti-EGFR agents.
Author:	Monti, M\|Motta, S
PMID:	17520582

545.
Journal:	Int J Biol Markers. 2007 Jan-Mar;22(1 Suppl 4):S62-70.
Title:	Cetuximab in colon cancer.
Author:	Giuliani, F\|Colucci, G
PMID:	17520583

546.
Journal:	Int J Biol Markers. 2007 Jan-Mar;22(1 Suppl 4):S88-93.
Title:	The future of anti-EGFR therapy.
Author:	D'Andrea, M R\|Gasparini, G
PMID:	17520586

547.
Journal:	Oncologist. 2007 May;12(5):577-83.
Title:	FDA drug approval summary: panitumumab (Vectibix).
Author:	Giusti, Ruthann M\|Shastri, Kaushikkumar A\|Cohen, Martin H\|Keegan, Patricia\|Pazdur, Richard
PMID:	17522246

548.
Journal:	Oncogene. 2007 May 28;26(25):3654-60.
Title:	Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer.
Author:	Galizia, G\|Lieto, E\|De Vita, F\|Orditura, M\|Castellano, P\|Troiani, T\|Imperatore, V\|Ciardiello, F
PMID:	17530019

549.
Journal:	Cancer Res. 2007 Jun 1;67(11):5389-96.
Title:	Regression of early and intermediate stages of colon cancer by targeting multiple members of the EGFR family with EGFR-related protein.
Author:	Schmelz, Eva M\|Xu, Hu\|Sengupta, Radha\|Du, Jianhua\|Banerjee, Sanjeev\|Sarkar, Fazlul H\|Rishi, Arun K\|Majumdar, Adhip P N
PMID:	17545620

550.
Journal:	Ai Zheng. 2007 Jun;26(6):647-51.
Title:	[Correlations of c-erb-B2, EGFR, and TGF-alpha expression to recurrence of Dukes'A and B colorectal carcinoma].
Author:	Liang, Jun-Lin\|Wan, De-Sen\|Pan, Zhi-Zhong\|Zhou, Zhi-Wei
PMID:	17562274

551.
Journal:	Dis Colon Rectum. 2007 Aug;50(8):1259-70.
Title:	EGFR-targeted therapies in colorectal cancer.
Author:	Overman, Michael J\|Hoff, Paulo M
PMID:	17566832

552.
Journal:	Clin Cancer Res. 2007 Jun 15;13(12):3597-604.
Title:	Epidermal growth factor receptor R497K polymorphism is a favorable prognostic factor for patients with colorectal carcinoma.
Author:	Wang, Wei-Shu\|Chen, Po-Min\|Chiou, Tzeon-Jye\|Liu, Jin-Hwang\|Lin, Jen-Kou\|Lin, Tzu-Chen\|Wang, Huann-Sheng\|Su, Yeu
PMID:	17575224

553.
Journal:	Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title:	Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author:	Mitchell, Clint\|Kabolizadeh, Peyman\|Ryan, John\|Roberts, John D\|Yacoub, Adly\|Curiel, David T\|Fisher, Paul B\|Hagan, Michael P\|Farrell, Nicholas P\|Grant, Steven\|Dent, Paul
PMID:	17578896

554.
Journal:	Br J Cancer. 2007 Jul 2;97(1):92-7. Epub 2007 Jun 19.
Title:	Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options.
Author:	Scartozzi, M\|Bearzi, I\|Berardi, R\|Mandolesi, A\|Pierantoni, C\|Cascinu, S
PMID:	17579627

555.
Journal:	Curr Oncol Rep. 2007 Jul;9(4):255-64.
Title:	Targeting the epidermal growth factor receptor in non-small-cell lung cancer: who, which, when, and how?
Author:	Juergens, Rosalyn\|Brahmer, Julie
PMID:	17588349

556.
Journal:	Ann Oncol. 2007 Jun;18 Suppl 6:vi16-21.
Title:	Panitumumab a novel drug in cancer treatment.
Author:	Carteni, G\|Fiorentino, R\|Vecchione, L\|Chiurazzi, B\|Battista, C
PMID:	17591813

557.
Journal:	Anticancer Res. 2007 May-Jun;27(3A):1337-41.
Title:	The clinical significance of circulating tumour cells in breast cancer and colorectal cancer patients.
Author:	Hauch, Siegfried\|Zimmermann, Silke\|Lankiewicz, Silke\|Zieglschmid, Veit\|Bocher, Oliver\|Albert, Winfried Hans
PMID:	17593628

558.
Journal:	Cancer. 2007 Aug 15;110(4):752-8.
Title:	First clinical experience of orally active epidermal growth factor receptor inhibitor combined with simplified FOLFOX6 as first-line treatment for metastatic colorectal cancer.
Author:	Zampino, Maria Giulia\|Magni, Elena\|Massacesi, Cristian\|Zaniboni, Alberto\|Martignetti, Angelo\|Zorzino, Laura\|Lorizzo, Katia\|Santoro, Luigi\|Boselli, Sabrina\|de Braud, Filippo
PMID:	17594712

559.
Journal:	Arch Iran Med. 2007 Jul;10(3):301-8.
Title:	Expression of epidermal growth factor receptor as a predictive factor for rectal cancer.
Author:	Motlagh, Ali\|Azadeh, Payam\|Fazlalizadeh, Abdolah\|Shahrad, Behrouz\|Shafaghi, Behrouz\|Fudazi, Mohammad\|Yosefi, Amirshahram\|Davaei, Manoochehr
PMID:	17604465

560.
Journal:	Recent Results Cancer Res. 2007;176:135-43.
Title:	Cetuximab: appraisal of a novel drug against colorectal cancer.
Author:	Hildebrandt, Bert\|le Coutre, Philipp\|Nicolaou, Annett\|Koble, Konrad\|Riess, Hanno\|Dorken, Bernd
PMID:	17607921

561.
Journal:	Differentiation. 2007 Nov;75(9):788-99.
Title:	Primary and acquired resistance to anti-EGFR targeted drugs in cancer therapy.
Author:	Morgillo, Floriana\|Bareschino, Maria Anna\|Bianco, Roberto\|Tortora, Giampaolo\|Ciardiello, Fortunato
PMID:	17608727

562.
Journal:	Cancer Res. 2007 Jul 1;67(13):6493-501.
Title:	The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells.
Author:	Adachi, Seiji\|Nagao, Tomokazu\|Ingolfsson, Helgi I\|Maxfield, Frederick R\|Andersen, Olaf S\|Kopelovich, Levy\|Weinstein, I Bernard
PMID:	17616711

563.
Journal:	Expert Rev Anticancer Ther. 2007 Jul;7(7):967-73.
Title:	Panitumumab in colorectal cancer.
Author:	Wainberg, Zev A\|Hecht, J Randolph
PMID:	17627455

564.
Journal:	Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12468-73. Epub 2007 Jul 16.
Title:	TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts.
Author:	Damiano, Vincenzo\|Caputo, Rosa\|Garofalo, Sonia\|Bianco, Roberto\|Rosa, Roberta\|Merola, Gerardina\|Gelardi, Teresa\|Racioppi, Luigi\|Fontanini, Gabriella\|De Placido, Sabino\|Kandimalla, Ekambar R\|Agrawal, Sudhir\|Ciardiello, Fortunato\|Tortora, Giampaolo
PMID:	17636117

565.
Journal:	J Immunol. 2007 Aug 1;179(3):2005-12.
Title:	Identification and characterization of ErbB-3-binding protein-1 as a target for immunotherapy.
Author:	Santegoets, Saskia J A M\|Schreurs, Marco W J\|Reurs, Anneke W\|Lindenberg, Jelle J\|Kueter, Esther W M\|van den Eertwegh, Alfons J M\|Hooijberg, Erik\|Brandwijk, Ricardo J\|Hufton, Simon E\|Hoogenboom, Hennie R\|Scheper, Rik J\|Somers, Veerle A\|de Gruijl, Tanja D
PMID:	17641068

566.
Journal:	Anticancer Res. 2007 Jul-Aug;27(4A):1823-32.
Title:	Tumor-associated gene expression in disseminated tumor cells correlates with disease progression and tumor stage in colorectal cancer.
Author:	Zieglschmid, Veit\|Hollmann, Christiane\|Mannel, Jenny\|Albert, Winfried\|Jaeschke-Melli, Stefan\|Eckstein, Birte\|Hillemann, Tina\|Greten, Tim F\|Gross, Eberhard\|Bocher, Oliver
PMID:	17649779

567.
Journal:	Cancer Nurs. 2007 Jul-Aug;30(4 Suppl 1):S1-9.
Title:	Targeting the epidermal growth factor receptor in colorectal carcinoma.
Author:	Kurtin, Sandra E
PMID:	17666985

568.
Journal:	Cancer Nurs. 2007 Jul-Aug;30(4 Suppl 1):S17-26.
Title:	Insights into the pathophysiology and management of dermatologic toxicities to EGFR-targeted therapies in colorectal cancer.
Author:	Lacouture, Mario E
PMID:	17666987

569.
Journal:	Clin Cancer Res. 2007 Aug 1;13(15 Pt 2):s4597-601.
Title:	Antibodies to the epidermal growth factor receptor in non small cell lung cancer: current status of matuzumab and panitumumab.
Author:	Socinski, Mark A
PMID:	17671148

570.
Journal:	J Clin Invest. 2007 Aug;117(8):2260-7.
Title:	Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
Author:	Groenestege, Wouter M Tiel\|Thebault, Stephanie\|van der Wijst, Jenny\|van den Berg, Dennis\|Janssen, Rob\|Tejpar, Sabine\|van den Heuvel, Lambertus P\|van Cutsem, Eric\|Hoenderop, Joost G\|Knoers, Nine V\|Bindels, Rene J
PMID:	17671655

571.
Journal:	Cancer. 2007 Sep 1;110(5):980-8.
Title:	Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer.
Author:	Hecht, J Randolph\|Patnaik, Amita\|Berlin, Jordan\|Venook, Alan\|Malik, Imtiaz\|Tchekmedyian, Simon\|Navale, Lynn\|Amado, Rafael G\|Meropol, Neal J
PMID:	17671985

572.
Journal:	Virchows Arch. 2007 Oct;451(4):763-9. Epub 2007 Aug 3.
Title:	Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer.
Author:	Zlobec, Inti\|Terracciano, Luigi\|Jass, Jeremy R\|Lugli, Alessandro
PMID:	17674041

573.
Journal:	Gan To Kagaku Ryoho. 2007 Aug;34(8):1192-5.
Title:	[Cetuximab].
Author:	Takiuchi, Hiroya
PMID:	17687200

574.
Journal:	Oncology (Williston Park). 2007 Jul;21(8):964-70; discussion 970, 974, 976-7.
Title:	Clinical use of monoclonal antibodies to the epidermal growth factor receptor in colorectal cancer.
Author:	Burtness, Barbara
PMID:	17715697

575.
Journal:	Appl Immunohistochem Mol Morphol. 2007 Sep;15(3):305-9.
Title:	Comparison of the Dako EGFR pharmDx kit and Zymed EGFR antibody for assessment of EGFR status in colorectal adenocarcinoma.
Author:	Buckley, Anne F\|Kakar, Sanjay
PMID:	17721276

576.
Journal:	Skin Therapy Lett. 2007 Jul-Aug;12(6):1-5.
Title:	Cutaneous reactions to anticancer agents targeting the epidermal growth factor receptor: a dermatology-oncology perspective.
Author:	Lacouture, M E\|Melosky, B L
PMID:	17762902

577.
Journal:	Cancer Res. 2007 Sep 1;67(17):8240-7.
Title:	Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab.
Author:	Lu, Yang\|Li, Xinqun\|Liang, Ke\|Luwor, Rodney\|Siddik, Zahid H\|Mills, Gordon B\|Mendelsohn, John\|Fan, Zhen
PMID:	17804738

578.
Journal:	ONS Connect. 2007;22(8 Suppl):33-4.
Title:	Targeted therapies in colorectal carcinoma: addressing toxicities associated with EGFR inhibitors.
Author:	Biedrzycki, Barbara A
PMID:	17824555

579.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2007 Jul;36(7):447-52.
Title:	[Protein overexpression and gene copy number of EGFR and HER2 in colorectal carcinoma].
Author:	Zeng, Xuan\|Wang, Peng\|Wu, Sha-fei\|Gao, Jie\|Liang, Zhi-yong\|Liu, Tong-hua
PMID:	17845756

580.
Journal:	Acta Oncol. 2007;46(8):1113-7.
Title:	Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer.
Author:	Spindler, Karen-Lise G\|Nielsen, Jens N\|Ornskov, Dorthe\|Brandslund, Ivan\|Jakobsen, Anders
PMID:	17851837

581.
Journal:	Acta Oncol. 2007;46(8):1118-22.
Title:	LRIG1 expression in colorectal cancer.
Author:	Ljuslinder, Ingrid\|Golovleva, Irina\|Palmqvist, Richard\|Oberg, Ake\|Stenling, Roger\|Jonsson, Yvonne\|Hedman, Hakan\|Henriksson, Roger\|Malmer, Beatrice
PMID:	17851870

582.
Journal:	Cell Prolif. 2007 Oct;40(5):768-79.
Title:	Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy.
Author:	Banu, N\|Buda, A\|Chell, S\|Elder, D\|Moorghen, M\|Paraskeva, C\|Qualtrough, D\|Pignatelli, M
PMID:	17877615

583.
Journal:	Anticancer Agents Med Chem. 2007 Sep;7(5):492-503.
Title:	Oncologists' current opinion on the treatment of colon carcinoma.
Author:	Majer, Martin\|Akerley, Wallace\|Kuwada, Scott K
PMID:	17896910

584.
Journal:	Cancer Res. 2007 Oct 1;67(19):9380-8.
Title:	Targeting cyclooxygenase-2 and the epidermal growth factor receptor for the prevention and treatment of intestinal cancer.
Author:	Buchanan, F Gregory\|Holla, Vijay\|Katkuri, Sharada\|Matta, Pranathi\|DuBois, Raymond N
PMID:	17909047

585.
Journal:	Oncology (Williston Park). 2007 Aug;21(9):1055-65; discussion 1065, 1070, 1075
Title:	Targeted therapy in rectal cancer.
Author:	Willett, Christopher G\|Duda, Dan G\|Czito, Brian G\|Bendell, Johanna C\|Clark, Jeffrey W\|Jain, Rakesh K
PMID:	17910311

586.
Journal:	Clin Transl Oncol. 2007 Sep;9(9):549-54.
Title:	Molecular markers in colorectal cancer: genetic bases for a customised treatment.
Author:	Casado, E\|De Castro, J\|Belda-Iniesta, C\|Cejas, P\|Feliu, J\|Sereno, M\|Gonzalez-Baron, M
PMID:	17921101

587.
Journal:	Nat Biotechnol. 2007 Oct;25(10):1134-43.
Title:	From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic mice.
Author:	Jakobovits, Aya\|Amado, Rafael G\|Yang, Xiaodong\|Roskos, Lorin\|Schwab, Gisela
PMID:	17921999

588.
Journal:	Curr Treat Options Oncol. 2007 Jun;8(3):239-51.
Title:	Molecular targets in squamous cell carcinoma of the head and neck.
Author:	Shirai, Keisuke\|O'Brien, Paul E
PMID:	17962911

589.
Journal:	Bull Cancer. 2007;94(7 Suppl):F227-30.
Title:	[Predictive factors of response to targeted therapies: the example of colorectal cancer].
Author:	Milano, Gerard
PMID:	17965001

590.
Journal:	Clin Cancer Res. 2007 Nov 1;13(21):6450-8.
Title:	Investigation of two dosing schedules of vandetanib (ZD6474), an inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling, in combination with irinotecan in a human colon cancer xenograft model.
Author:	Troiani, Teresa\|Serkova, Natalie J\|Gustafson, Daniel L\|Henthorn, Thomas K\|Lockerbie, Owen\|Merz, Andrea\|Long, Michael\|Morrow, Mark\|Ciardiello, Fortunato\|Eckhardt, S Gail
PMID:	17975157

591.
Journal:	World J Gastroenterol. 2007 Nov 28;13(44):5845-56.
Title:	Exploiting novel molecular targets in gastrointestinal cancers.
Author:	Ma, Wen W\|Hidalgo, Manuel
PMID:	17990350

592.
Journal:	N Engl J Med. 2007 Nov 15;357(20):2040-8.
Title:	Cetuximab for the treatment of colorectal cancer.
Author:	Jonker, Derek J\|O'Callaghan, Chris J\|Karapetis, Christos S\|Zalcberg, John R\|Tu, Dongsheng\|Au, Heather-Jane\|Berry, Scott R\|Krahn, Marianne\|Price, Timothy\|Simes, R John\|Tebbutt, Niall C\|van Hazel, Guy\|Wierzbicki, Rafal\|Langer, Christiane\|Moore, Malcolm J
PMID:	18003960

593.
Journal:	Cancer Res. 2007 Nov 15;67(22):10736-43.
Title:	Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types.
Author:	Martin, Eric S\|Tonon, Giovanni\|Sinha, Raktim\|Xiao, Yonghong\|Feng, Bin\|Kimmelman, Alec C\|Protopopov, Alexei\|Ivanova, Elena\|Brennan, Cameron\|Montgomery, Kate\|Kucherlapati, Raju\|Bailey, Gerald\|Redston, Mark\|Chin, Lynda\|DePinho, Ronald A
PMID:	18006816

594.
Journal:	Clin Colorectal Cancer. 2007 Oct;6 Suppl 2:S42-6.
Title:	First-line use of anti-epidermal growth factor receptor monoclonal antibodies in metastatic colorectal cancer.
Author:	Lee, James J\|Chu, Edward
PMID:	18021486

595.
Journal:	Clin Colorectal Cancer. 2007 Oct;6 Suppl 2:S47-52.
Title:	The role of epidermal growth factor receptor-targeted antibody therapy in previously treated colorectal cancer.
Author:	Watkins, David\|Cunningham, David
PMID:	18021487

596.
Journal:	Clin Colorectal Cancer. 2007 Oct;6 Suppl 2:S60-5.
Title:	Optimizing administration of epidermal growth factor receptor-targeted agents in the treatment of colorectal cancer.
Author:	Van Cutsem, Eric
PMID:	18021489

597.
Journal:	Clin Colorectal Cancer. 2007 Nov;6(10):691-9.
Title:	Role of tyrosine kinase inhibitors in the treatment of advanced colorectal cancer.
Author:	Gravalos, Cristina\|Cassinello, Javier\|Fernandez-Ranada, Isabel\|Holgado, Esther
PMID:	18039422

598.
Journal:	Farm Hosp. 2007 Sep-Oct;31(5):264-9.
Title:	[Treatment with cetuximab in metastatic colorectal cancer patients who do not express the epidermal growth factor receptor].
Author:	Huertas Fernandez, M J\|Rodriguez Mateos, M E\|Gomez Reina, M J\|Martinez Bautista, M J\|Sanchez Martinez, I
PMID:	18052628

599.
Journal:	Gastroenterology. 2007 Dec;133(6):1869-81. Epub 2007 Sep 14.
Title:	Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors.
Author:	Fukata, Masayuki\|Chen, Anli\|Vamadevan, Arunan S\|Cohen, Jason\|Breglio, Keith\|Krishnareddy, Suneeta\|Hsu, David\|Xu, Ruliang\|Harpaz, Noam\|Dannenberg, Andrew J\|Subbaramaiah, Kotha\|Cooper, Harry S\|Itzkowitz, Steven H\|Abreu, Maria T
PMID:	18054559

600.
Journal:	Neoplasia. 2007 Dec;9(12):1066-77.
Title:	Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice.
Author:	Sasaki, Takamitsu\|Kitadai, Yasuhiko\|Nakamura, Toru\|Kim, Jang-Seong\|Tsan, Rachel Z\|Kuwai, Toshio\|Langley, Robert R\|Fan, Dominic\|Kim, Sun-Jin\|Fidler, Isaiah J
PMID:	18084614

601.
Journal:	Ann Pathol. 2007 Oct;27(5):341-3.
Title:	[EGFR and colorectal cancer: what's new?].
Author:	Sabourin, Jean-Christophe\|Bibeau, Frederic
PMID:	18185468

602.
Journal:	Clin Colorectal Cancer. 2007 Dec;7 Suppl 1:S8-15.
Title:	A retrospective on the inhibition of epidermal growth factor receptor as a therapeutic strategy for patients with relapsed metastatic colorectal cancer: impact on treatment of today's patients.
Author:	Jackson, Christopher\|Cunningham, David
PMID:	18361806

603.
Journal:	Gastrointest Cancer Res. 2007;1(4 Suppl 2):S37-41.
Title:	Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic.
Author:	Kopetz, Scott
PMID:	19360146

604.
Journal:	Gastrointest Cancer Res. 2007;1(4 Suppl 2):S47-9.
Title:	Update on targeted agents for adjuvant treatment of colon cancer in 2006.
Author:	de Gramont, Aimery\|Larsen, Annette K\|Tournigand, Christophe\|Louvet, Christophe\|Andre, Thierry
PMID:	19360148

605.
Journal:	Biologics. 2007 Jun;1(2):77-91.
Title:	Cetuximab in the management of colorectal cancer.
Author:	Lenz, Heinz-Josef
PMID:	19707318

606.
Journal:	Int J Biol Markers. 2007 S4 - Jan-Mar;22(4):53-61.
Title:	Clinical management of cutaneous toxicity of anti-EGFR agents.
Author:	Monti, M\|Motta, S
PMID:	28207115

607.
Journal:	Int J Biol Markers. 2007 S4 - Jan-Mar;22(4):62-70.
Title:	Cetuximab in colon cancer.
Author:	Giuliani, F\|Colucci, G
PMID:	28207116

608.
Journal:	Int J Biol Markers. 2007 S4 - Jan-Mar;22(4):88-93.
Title:	The future of anti-EGFR therapy.
Author:	D'Andrea, M R\|Gasparini, G
PMID:	28207119

609.
Journal:	Colorectal Dis. 2008 Feb;10(2):170-8. Epub 2007 Aug 16.
Title:	Epidermal growth factor receptor in colorectal carcinoma: correlation with clinico-pathological prognostic factors.
Author:	Abd El All, H S\|Mishriky, A M\|Mohamed, F A
PMID:	17711501

610.
Journal:	Int J Cancer. 2008 Jan 15;122(2):267-73.
Title:	Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.
Author:	Patel, Bhaumik B\|Sengupta, Radha\|Qazi, Sadia\|Vachhani, Hetal\|Yu, Yingjie\|Rishi, Arun K\|Majumdar, Adhip P N
PMID:	17918158

611.
Journal:	Ann Oncol. 2008 Apr;19(4):717-23. Epub 2007 Oct 31.
Title:	EGFR FISH assay predicts for response to cetuximab in chemotherapy refractory colorectal cancer patients.
Author:	Cappuzzo, F\|Finocchiaro, G\|Rossi, E\|Janne, P A\|Carnaghi, C\|Calandri, C\|Bencardino, K\|Ligorio, C\|Ciardiello, F\|Pressiani, T\|Destro, A\|Roncalli, M\|Crino, L\|Franklin, W A\|Santoro, A\|Varella-Garcia, M
PMID:	17974556

612.
Journal:	Ann Oncol. 2008 Feb;19(2):332-9. Epub 2007 Nov 6.
Title:	A phase Ib dose-escalation study of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer patients.
Author:	Van Cutsem, E\|Verslype, C\|Beale, P\|Clarke, S\|Bugat, R\|Rakhit, A\|Fettner, S H\|Brennscheidt, U\|Feyereislova, A\|Delord, J-P
PMID:	17986625

613.
Journal:	Ann Surg Oncol. 2008 Feb;15(2):649-54. Epub 2007 Nov 7.
Title:	Cetuximab shows activity in colorectal cancer patients with tumors for which FISH analysis does not detect an increase in EGFR gene copy number.
Author:	Italiano, Antoine\|Follana, Philippe\|Caroli, Francois-Xavier\|Badetti, Jean-Luc\|Benchimol, Daniel\|Garnier, Georges\|Gugenheim, Jean\|Haudebourg, Juliette\|Keslair, Frederique\|Lesbats, Gerard\|Lledo, Gerard\|Roussel, Jean-Francois\|Pedeutour, Florence\|Francois, Er
PMID:	17987340

614.
Journal:	Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):203-12.
Title:	Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism.
Author:	Dittmann, Klaus H\|Mayer, Claus\|Ohneseit, Petra A\|Raju, Uma\|Andratschke, Nickolaus H\|Milas, Luka\|Rodemann, H Peter
PMID:	17996386

615.
Journal:	Crit Rev Oncol Hematol. 2008 Jan;65(1):8-20. Epub 2007 Nov 19.
Title:	Targeting the epidermal growth factor receptor in metastatic colorectal cancer.
Author:	Ng, Kimmie\|Zhu, Andrew X
PMID:	18006328

616.
Journal:	Br J Cancer. 2008 Jan 15;98(1):71-6. Epub 2007 Dec 4.
Title:	A combination of gefitinib and FOLFOX-4 as first-line treatment in advanced colorectal cancer patients. A GISCAD multicentre phase II study including a biological analysis of EGFR overexpression, amplification and NF-kB activation.
Author:	Cascinu, S\|Berardi, R\|Salvagni, S\|Beretta, G D\|Catalano, V\|Pucci, F\|Sobrero, A\|Tagliaferri, P\|Labianca, R\|Scartozzi, M\|Crocicchio, F\|Mari, E\|Ardizzoni, A
PMID:	18059397

617.
Journal:	J Cell Physiol. 2008 May;215(2):538-49.
Title:	Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
Author:	Raufman, Jean-Pierre\|Shant, Jasleen\|Guo, Chang Yue\|Roy, Sanjit\|Cheng, Kunrong
PMID:	18064605

618.
Journal:	Ann Oncol. 2008 Apr;19(4):711-6. Epub 2007 Dec 10.
Title:	First-line single-agent cetuximab in patients with advanced colorectal cancer.
Author:	Pessino, A\|Artale, S\|Sciallero, S\|Guglielmi, A\|Fornarini, G\|Andreotti, I C\|Mammoliti, S\|Comandini, D\|Caprioni, F\|Bennicelli, E\|Andretta, V\|Siena, S\|Sobrero, A
PMID:	18073221

619.
Journal:	Acta Oncol. 2008;47(1):9-19.
Title:	Current situation of Panitumumab, Matuzumab, Nimotuzumab and Zalutumumab.
Author:	Rivera, Fernando\|Vega-Villegas, Ma Eugenia\|Lopez-Brea, Marta F\|Marquez, Raul
PMID:	18097777

620.
Journal:	Pharmacogenomics. 2008 Jan;9(1):55-69.
Title:	EGF-receptor targeting with monoclonal antibodies in colorectal carcinomas: rationale for a pharmacogenomic approach.
Author:	Loupakis, Fotios\|Vasile, Enrico\|Santini, Daniele\|Masi, Gianluca\|Falcone, Alfredo\|Graziano, Francesco
PMID:	18154448

621.
Journal:	Anticancer Drugs. 2008 Feb;19(2):99-113.
Title:	Cetuximab, its clinical use and future perspectives.
Author:	Rivera, Fernando\|Vega-Villegas, Maria Eugenia\|Lopez-Brea, Marta Francisca
PMID:	18176106

622.
Journal:	Br J Cancer. 2008 Jan 29;98(2):450-6.
Title:	Combined analysis of VEGF and EGFR predicts complete tumour response in rectal cancer treated with preoperative radiotherapy.
Author:	Zlobec, I\|Vuong, T\|Compton, C C\|Lugli, A\|Michel, R P\|Hayashi, S\|Jass, J R
PMID:	18182986

623.
Journal:	Crit Rev Oncol Hematol. 2008 Apr;66(1):21-30.
Title:	Potential predictive markers of response to EGFR-targeted therapies in colorectal cancer.
Author:	Spano, Jean Philippe\|Milano, Gerard\|Vignot, Stephane\|Khayat, David
PMID:	18206383

624.
Journal:	Clin Transl Oncol. 2008 Jan;10(1):6-13.
Title:	EGFR and colon cancer: a clinical view.
Author:	de Castro-Carpeno, J\|Belda-Iniesta, C\|Casado Saenz, E\|Hernandez Agudo, E\|Feliu Batlle, J\|Gonzalez Baron, M
PMID:	18208787

625.
Journal:	Cancer Radiother. 2008 Jan;12(1):25-30.
Title:	[Potential combination of target therapy and radiation therapy in GI tract cancers].
Author:	Maingon, P\|Crehange, G\|Peignaux, K\|Truc, G
PMID:	18226575

626.
Journal:	Bull Cancer. 2008 Jan;95(1):133-40.
Title:	[Predictive factors of response to anti-EGFR treatments in colorectal cancer].
Author:	Lievre, Astrid\|Laurent-Puig, Pierre
PMID:	18230579

627.
Journal:	Cancer Res. 2008 Feb 1;68(3):815-25.
Title:	The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition.
Author:	Vigneron, Arnaud\|Gamelin, Erick\|Coqueret, Olivier
PMID:	18245483

628.
Journal:	Ann Oncol. 2008 Apr;19(4):734-8.
Title:	A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity.
Author:	Tol, J\|Koopman, M\|Rodenburg, C J\|Cats, A\|Creemers, G J\|Schrama, J G\|Erdkamp, F L G\|Vos, A H\|Mol, L\|Antonini, N F\|Punt, C J A
PMID:	18272912

629.
Journal:	Clin Cancer Res. 2008 Feb 15;14(4):1182-91.
Title:	TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer.
Author:	Merchant, Nipun B\|Voskresensky, Igor\|Rogers, Christopher M\|Lafleur, Bonnie\|Dempsey, Peter J\|Graves-Deal, Ramona\|Revetta, Frank\|Foutch, A Coe\|Rothenberg, Mace L\|Washington, Mary K\|Coffey, Robert J
PMID:	18281553

630.
Journal:	World J Gastroenterol. 2008 Feb 21;14(7):1053-9.
Title:	Frequent mutations of the CA simple sequence repeat in intron 1 of EGFR in mismatch repair-deficient colorectal cancers.
Author:	Buisine, Marie-Pierre\|Wacrenier, Agnes\|Mariette, Christophe\|Leteurtre, Emmanuelle\|Escande, Fabienne\|Aissi, Sana\|Ketele, Amandine\|Leclercq, Annette\|Porchet, Nicole\|Lesuffleur, Thecla
PMID:	18286687

631.
Journal:	Eur J Cancer. 2008 Mar;44(5):652-62.
Title:	Where to position monoclonal antibodies in first-line treatment of advanced colorectal cancer.
Author:	Jackson, Christopher\|Cunningham, David
PMID:	18313913

632.
Journal:	Glycobiology. 2008 May;18(5):395-407.
Title:	The AP-2alpha transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene.
Author:	Choi, Hee-Jung\|Chung, Tae-Wook\|Kim, Seok-Jo\|Cho, Soo-Young\|Lee, Young-Seek\|Lee, Young-Choon\|Ko, Jeong-Heon\|Kim, Cheorl-Ho
PMID:	18316341

633.
Journal:	J Clin Oncol. 2008 Apr 1;26(10):1626-34.
Title:	Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.
Author:	Amado, Rafael G\|Wolf, Michael\|Peeters, Marc\|Van Cutsem, Eric\|Siena, Salvatore\|Freeman, Daniel J\|Juan, Todd\|Sikorski, Robert\|Suggs, Sid\|Radinsky, Robert\|Patterson, Scott D\|Chang, David D
PMID:	18316791

634.
Journal:	Br J Cancer. 2008 Mar 11;98(5):923-30.
Title:	Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs.
Author:	Bianco, R\|Garofalo, S\|Rosa, R\|Damiano, V\|Gelardi, T\|Daniele, G\|Marciano, R\|Ciardiello, F\|Tortora, G
PMID:	18319715

635.
Journal:	Clin Exp Metastasis. 2008;25(4):477-89.
Title:	Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy.
Author:	Kuwai, Toshio\|Nakamura, Toru\|Sasaki, Takamitsu\|Kitadai, Yasuhiko\|Kim, Jang-Seong\|Langley, Robert R\|Fan, Dominic\|Wang, Xuemei\|Do, Kim-Anh\|Kim, Sun-Jin\|Fidler, Isaiah J
PMID:	18324358

636.
Journal:	Cancer Chemother Pharmacol. 2008 Dec;63(1):139-48.
Title:	Epidermal growth factor receptor serum (sEGFR) level may predict response in patients with EGFR-positive advanced colorectal cancer treated with gefitinib?
Author:	Zampino, M G\|Magni, E\|Santoro, L\|Zorzino, L\|Dell'Orto, P\|Sonzogni, A\|Fazio, N\|Monfardini, L\|Chiappa, A\|Biffi, R\|de Braud, F
PMID:	18327586

637.
Journal:	Cancer Res. 2008 Mar 15;68(6):1953-61.
Title:	PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab.
Author:	Jhawer, Minaxi\|Goel, Sanjay\|Wilson, Andrew J\|Montagna, Cristina\|Ling, Yi-He\|Byun, Do-Sun\|Nasser, Shannon\|Arango, Diego\|Shin, Joongho\|Klampfer, Lidija\|Augenlicht, Leonard H\|Perez-Soler, Roman\|Mariadason, John M
PMID:	18339877

638.
Journal:	Clin Ther. 2008 Jan;30(1):14-30.
Title:	Panitumumab: human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer.
Author:	Wu, Mei\|Rivkin, Anastasia\|Pham, Trinh
PMID:	18343240

639.
Journal:	Mol Cancer Ther. 2008 Mar;7(3):590-8.
Title:	Dual inhibition of VEGFR and EGFR signaling reduces the incidence and size of intestinal adenomas in Apc(Min/+) mice.
Author:	Alferez, Denis\|Wilkinson, Robert W\|Watkins, Jim\|Poulsom, Richard\|Mandir, Nikki\|Wedge, Stephen R\|Pyrah, Ian T\|Smith, Neil R\|Jackson, Lynsay\|Ryan, Anderson J\|Goodlad, Robert A
PMID:	18347145

640.
Journal:	J Clin Oncol. 2008 Mar 20;26(9):1427-34.
Title:	Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer.
Author:	Graziano, Francesco\|Ruzzo, Annamaria\|Loupakis, Fotios\|Canestrari, Emanuele\|Santini, Daniele\|Catalano, Vincenzo\|Bisonni, Renato\|Torresi, Umberto\|Floriani, Irene\|Schiavon, Gaia\|Andreoni, Francesca\|Maltese, Paolo\|Rulli, Eliana\|Humar, Bostjan\|Falcone, Alfredo
PMID:	18349392

641.
Journal:	Ophthalmologe. 2008 Mar;105(3):269-73.
Title:	[Topical application of EGF for the therapy of persisting corneal erosion under cetuximab treatment].
Author:	Forster, C G\|Cursiefen, C\|Kruse, F E
PMID:	18350301

642.
Journal:	Expert Rev Mol Diagn. 2008 Mar;8(2):141-8.
Title:	Implications of EGFR PharmDx kit for cetuximab eligibility.
Author:	Ensinger, Christian\|Sterlacci, William
PMID:	18366301

643.
Journal:	J Cell Physiol. 2008 Sep;216(3):698-707.
Title:	Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells.
Author:	Cascone, Tina\|Morelli, Maria Pia\|Morgillo, Floriana\|Kim, Woo-Young\|Rodolico, Gabriella\|Pepe, Stefano\|Tortora, Giampaolo\|Berrino, Liberato\|Lee, Ho-Young\|Heymach, John V\|Ciardiello, Fortunato
PMID:	18381602

644.
Journal:	Pharmacogenomics. 2008 Apr;9(4):463-7.
Title:	DxS Ltd.
Author:	Cross, Joanne
PMID:	18384259

645.
Journal:	Curr Opin Mol Ther. 2008 Apr;10(2):124-31.
Title:	EGFR-targeted therapy in colorectal cancer: does immunohistochemistry deserve a role in predicting the response to cetuximab?
Author:	Valentini, Anna Maria\|Pirrelli, Michele\|Caruso, Maria Lucia
PMID:	18386224

646.
Journal:	Cancer Res. 2008 Apr 15;68(8):3037-42.
Title:	Gender-related survival differences associated with EGFR polymorphisms in metastatic colon cancer.
Author:	Press, Oliver A\|Zhang, Wu\|Gordon, Michael A\|Yang, Dongyun\|Lurje, Georg\|Iqbal, Syma\|El-Khoueiry, Anthony\|Lenz, Heinz-Josef
PMID:	18413774

647.
Journal:	Clin Cancer Res. 2008 Apr 15;14(8):2253-62.
Title:	Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model.
Author:	Dougherty, Urszula\|Sehdev, Amikar\|Cerda, Sonia\|Mustafi, Reba\|Little, Nathaniel\|Yuan, Weihua\|Jagadeeswaran, Sujatha\|Chumsangsri, Anusara\|Delgado, Jorge\|Tretiakova, Maria\|Joseph, Loren\|Hart, John\|Cohen, Ezra E W\|Aluri, Lata\|Fichera, Alessandro\|Bissonnette,
PMID:	18413814

648.
Journal:	Clin Cancer Res. 2008 Apr 15;14(8):2351-6.
Title:	Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer.
Author:	Yamada, Michiyo\|Ichikawa, Yasushi\|Yamagishi, Shigeru\|Momiyama, Nobuyoshi\|Ota, Mitsuyoshi\|Fujii, Syoichi\|Tanaka, Kuniya\|Togo, Shinji\|Ohki, Shigeo\|Shimada, Hiroshi
PMID:	18413824

649.
Journal:	Zentralbl Chir. 2008 Apr;133(2):101-6.
Title:	[Antibody treatment in colorectal cancer--what the surgeon needs to know].
Author:	Thalheimer, A\|Illert, B\|Reimer, P\|Bueter, M\|Thiede, A\|Gasser, M\|Fein, M\|Waaga-Gasser, A-M\|Meyer, D
PMID:	18415895

650.
Journal:	J Agric Food Chem. 2008 May 14;56(9):3010-5.
Title:	Oak ellagitannins suppress the phosphorylation of the epidermal growth factor receptor in human colon carcinoma cells.
Author:	Fridrich, Diana\|Glabasnia, Arne\|Fritz, Jessica\|Esselen, Melanie\|Pahlke, Gudrun\|Hofmann, Thomas\|Marko, Doris
PMID:	18419129

651.
Journal:	Cancer Sci. 2008 Jul;99(7):1471-8.
Title:	Interleukin-2 potentiation of cetuximab antitumor activity for epidermal growth factor receptor-overexpressing gastric cancer xenografts through antibody-dependent cellular cytotoxicity.
Author:	Hara, Masayasu\|Nakanishi, Hayao\|Tsujimura, Kunio\|Matsui, Makoto\|Yatabe, Yasushi\|Manabe, Tadao\|Tatematsu, Masae
PMID:	18422755

652.
Journal:	Mod Pathol. 2008 May;21 Suppl 2:S23-30.
Title:	Targeted therapy of cancer: new roles for pathologists in colorectal cancer.
Author:	Hamilton, Stanley R
PMID:	18437170

653.
Journal:	Lancet Oncol. 2008 May;9(5):402-3.
Title:	EGFR FISH in colorectal cancer: what is the current reality?
Author:	Moroni, Mauro\|Sartore-Bianchi, Andrea\|Veronese, Silvio\|Siena, Salvatore
PMID:	18452847

654.
Journal:	Cancer Biother Radiopharm. 2008 Apr;23(2):158-71.
Title:	Receptor-binding, biodistribution, and metabolism studies of 64Cu-DOTA-cetuximab, a PET-imaging agent for epidermal growth-factor receptor-positive tumors.
Author:	Ping Li, Wen\|Meyer, Laura A\|Capretto, David A\|Sherman, Christopher D\|Anderson, Carolyn J
PMID:	18454685

655.
Journal:	Neoplasia. 2008 May;10(5):489-500.
Title:	Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors.
Author:	Kuwai, Toshio\|Nakamura, Toru\|Sasaki, Takamitsu\|Kim, Sun-Jin\|Fan, Dominic\|Villares, Gabriel J\|Zigler, Maya\|Wang, Hua\|Bar-Eli, Menashe\|Kerbel, Robert S\|Fidler, Isaiah J
PMID:	18472966

656.
Journal:	Gan To Kagaku Ryoho. 2008 May;35(5):725-30.
Title:	[Molecular target therapy and chemotherapy for advanced colorectal cancer].
Author:	Nakashima, Koji\|Yamazaki, Kentaro\|Boku, Narikazu
PMID:	18487907

657.
Journal:	Oncol Rep. 2008 Jun;19(6):1541-4.
Title:	Mutations of epidermal growth factor receptor in colon cancer indicate susceptibility or resistance to gefitinib.
Author:	Zhang, Xiang\|Nagahara, Hisashi\|Mimori, Koshi\|Inoue, Hiroshi\|Sawada, Tetsuji\|Ohira, Masaichi\|Hirakawa, Kosei\|Mori, Masaki
PMID:	18497962

658.
Journal:	Int J Oncol. 2008 Jun;32(6):1305-10.
Title:	Mechanism of resistance to chemoradiation in p53 mutant human colon cancer.
Author:	Hiro, Junichiro\|Inoue, Yasuhiro\|Toiyama, Yuji\|Miki, Chikao\|Kusunoki, Masato
PMID:	18497992

659.
Journal:	Am J Health Syst Pharm. 2008 Jun 1;65(11 Suppl 4):S15-21; quiz S22-4.
Title:	Current and emerging therapies for metastatic colorectal cancer: applying research findings to clinical practice.
Author:	Hecht, J Randolph
PMID:	18499885

660.
Journal:	Am J Health Syst Pharm. 2008 Jun 1;65(11 Suppl 4):S3-7; quiz S22-4.
Title:	Development of monoclonal antibodies for the treatment of colorectal cancer.
Author:	Goodin, Susan
PMID:	18499888

661.
Journal:	Clin Colorectal Cancer. 2008 Mar;7(2):105-9.
Title:	Current questions in the treatment of advanced colorectal cancer: the CAIRO studies of the Dutch Colorectal Cancer Group.
Author:	Simkens, Lieke\|Tol, Jolien\|Koopman, Miriam\|Mol, Linda\|Antonini, Ninja\|van Krieken, Hans\|Punt, Cornelis
PMID:	18501069

662.
Journal:	Pharmacotherapy. 2008 Jun;28(6):742-54.
Title:	Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer.
Author:	Jean, Gary W\|Shah, Sachin R
PMID:	18503402

663.
Journal:	Nat Clin Pract Oncol. 2008 Jul;5(7):415-25.
Title:	Drug Insight: panitumumab, a human EGFR-targeted monoclonal antibody with promising clinical activity in colorectal cancer.
Author:	Mano, Max\|Humblet, Yves
PMID:	18506165

664.
Journal:	Anticancer Res. 2008 Mar-Apr;28(2A):895-906.
Title:	Rosiglitazone induces caveolin-1 by PPARgamma-dependent and PPRE-independent mechanisms: the role of EGF receptor signaling and its effect on cancer cell drug resistance.
Author:	Tencer, Lilach\|Burgermeister, Elke\|Ebert, Matthias P\|Liscovitch, Mordechai
PMID:	18507034

665.
Journal:	BMC Cancer. 2008 Jun 10;8:169.
Title:	A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment.
Author:	Goncalves, Anthony\|Esteyries, Severine\|Taylor-Smedra, Brynn\|Lagarde, Arnaud\|Ayadi, Mounay\|Monges, Genevieve\|Bertucci, Francois\|Esterni, Benjamin\|Delpero, Jean-Robert\|Turrini, Olivier\|Lelong, Bernard\|Viens, Patrice\|Borg, Jean-Paul\|Birnbaum, Daniel\|Olschwan
PMID:	18544172

666.
Journal:	Br J Cancer. 2008 Jul 8;99(1):83-9.
Title:	Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients.
Author:	Cappuzzo, F\|Varella-Garcia, M\|Finocchiaro, G\|Skokan, M\|Gajapathy, S\|Carnaghi, C\|Rimassa, L\|Rossi, E\|Ligorio, C\|Di Tommaso, L\|Holmes, A J\|Toschi, L\|Tallini, G\|Destro, A\|Roncalli, M\|Santoro, A\|Janne, P A
PMID:	18577988

667.
Journal:	Am J Pathol. 2008 Jul;173(1):205-16.
Title:	Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model.
Author:	Sasaki, Takamitsu\|Nakamura, Toru\|Rebhun, Robert B\|Cheng, Hua\|Hale, Katherine Stemke\|Tsan, Rachel Z\|Fidler, Isaiah J\|Langley, Robert R
PMID:	18583324

668.
Journal:	Carcinogenesis. 2008 Oct;29(10):1986-93.
Title:	(-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells.
Author:	Adachi, Seiji\|Nagao, Tomokazu\|To, Satoshi\|Joe, Andrew K\|Shimizu, Masahito\|Matsushima-Nishiwaki, Rie\|Kozawa, Osamu\|Moriwaki, Hisataka\|Maxfield, Frederick R\|Weinstein, I Bernard
PMID:	18586691

669.
Journal:	Mol Nutr Food Res. 2008 Jul;52(7):815-22.
Title:	Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation.
Author:	Fridrich, Diana\|Teller, Nicole\|Esselen, Melanie\|Pahlke, Gudrun\|Marko, Doris
PMID:	18618485

670.
Journal:	Hum Pathol. 2008 Oct;39(10):1483-94.
Title:	Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.
Author:	Furlan, Daniela\|Sahnane, Nora\|Carnevali, Ileana\|Cerutti, Roberta\|Bertoni, Francesco\|Kwee, Ivo\|Uccella, Silvia\|Bertolini, Valentina\|Chiaravalli, Anna Maria\|Capella, Carlo
PMID:	18619649

671.
Journal:	Ann Oncol. 2008 Dec;19(12):2033-8.
Title:	Epidermal growth factor receptor (EGFR) status and K-Ras mutations in colorectal cancer.
Author:	Milano, G\|Etienne-Grimaldi, M-C\|Dahan, L\|Francoual, M\|Spano, J-P\|Benchimol, D\|Chazal, M\|Letoublon, C\|Andre, T\|Gilly, F-N\|Delpero, J-R\|Formento, J-L
PMID:	18632722

672.
Journal:	World J Gastroenterol. 2008 Jul 14;14(26):4156-67.
Title:	VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab.
Author:	Moehler, Markus\|Frings, Christian\|Mueller, Annett\|Gockel, Ines\|Schimanski, Carl-C\|Biesterfeld, Stefan\|Galle, Peter-R\|Holtmann, Martin-H
PMID:	18636661

673.
Journal:	J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 1):1204-7.
Title:	Does hyaluronic acid stimulate tumor growth after endoscopic mucosal resection?
Author:	Sohn, Dae Kyung\|Chang, Hee Jin\|Choi, Hyo Seong\|Jeong, Seung-Yong\|Kook, Myeong-Cherl\|Kim, Chan Gyoo\|Choi, Il Ju
PMID:	18637056

674.
Journal:	Magy Onkol. 2008 Jun;52(2):185-91.
Title:	[The RAS paradox of the EGFR-targeted therapy in colorectal cancer].
Author:	Timar, Jozsef\|Lang, Istvan
PMID:	18640895

675.
Journal:	Pol J Pathol. 2008;59(2):93-6.
Title:	KRAS mutation profile in colorectal carcinoma and novel mutation--internal tandem duplication in KRAS.
Author:	Wojcik, Piotr\|Kulig, Jan\|Okon, Krzysztof\|Zazula, Monika\|Mozdzioch, Ilona\|Niepsuj, Anna\|Stachura, Jerzy
PMID:	18669174

676.
Journal:	Clin Cancer Res. 2008 Aug 1;14(15):4830-5.
Title:	K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy.
Author:	Etienne-Grimaldi, Marie-Christine\|Formento, Jean-Louis\|Francoual, Mireille\|Francois, Eric\|Formento, Patricia\|Renee, Nicole\|Laurent-Puig, Pierre\|Chazal, Maurice\|Benchimol, Daniel\|Delpero, Jean-Robert\|Letoublon, Christian\|Pezet, Denis\|Seitz, Jean-Francois\|M
PMID:	18676755

677.
Journal:	Pharmacogenomics. 2008 Aug;9(8):1079-99.
Title:	Pharmacogenetics in colorectal cancer: a systematic review.
Author:	Funke, Silvia\|Brenner, Hermann\|Chang-Claude, Jenny
PMID:	18681783

678.
Journal:	BMC Cancer. 2008 Aug 8;8:227.
Title:	Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines.
Author:	Solmi, Rossella\|Lauriola, Mattia\|Francesconi, Mirko\|Martini, Desiree\|Voltattorni, Manuela\|Ceccarelli, Claudio\|Ugolini, Giampaolo\|Rosati, Giancarlo\|Zanotti, Simone\|Montroni, Isacco\|Mattei, Gabriella\|Taffurelli, Mario\|Santini, Donatella\|Pezzetti, Furio\|Rugg
PMID:	18691415

679.
Journal:	J Med Chem. 2008 Sep 11;51(17):5463-7.
Title:	Parallel synthesis and cytotoxicity evaluation of a polyamine-quinone conjugates library.
Author:	Bolognesi, Maria Laura\|Calonghi, Natalia\|Mangano, Chiara\|Masotti, Lanfranco\|Melchiorre, Carlo
PMID:	18698755

680.
Journal:	BMC Cancer. 2008 Aug 13;8:234.
Title:	Potential value of PTEN in predicting cetuximab response in colorectal cancer: an exploratory study.
Author:	Razis, Evangelia\|Briasoulis, Evangelos\|Vrettou, Eleni\|Skarlos, Dimosthenis V\|Papamichael, Dimitrios\|Kostopoulos, Ioannis\|Samantas, Epaminontas\|Xanthakis, Ioannis\|Bobos, Mattheos\|Galanidi, Eleni\|Bai, Maria\|Gikonti, Ioanna\|Koukouma, Alona\|Kafiri, Georgia\|Pa
PMID:	18700047

681.
Journal:	Cancer Res. 2008 Aug 15;68(16):6569-77.
Title:	Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion.
Author:	Shida, Dai\|Fang, Xianjun\|Kordula, Tomasz\|Takabe, Kazuaki\|Lepine, Sandrine\|Alvarez, Sergio E\|Milstien, Sheldon\|Spiegel, Sarah
PMID:	18701480

682.
Journal:	Acta Gastroenterol Belg. 2008 Apr-Jun;71(2):213-8.
Title:	EGFR-immunohistochemistry in colorectal cancer and non-small cell lung cancer: comparison of 3 commercially available EGFR-antibodies.
Author:	Buffet, W\|Geboes, K P\|Dehertogh, G\|Geboes, K
PMID:	18720932

683.
Journal:	Curr Oncol. 2008 Aug;15(4):196-7.
Title:	Cetuximab treatment in a patient with metastatic colorectal cancer and psoriasis.
Author:	Neyns, B\|Meert, V\|Vandenbroucke, F
PMID:	18769609

684.
Journal:	Onkologie. 2008 Sep;31(8-9):464-7.
Title:	Complete remission in a colon cancer patient with a large, irresectable liver metastasis after XELOX/cetuximab/bevacizumab treatment.
Author:	Weihrauch, Martin R\|Stippel, Dirk\|Fries, Jochen W U\|Arnold, Dirk\|Bovenschulte, Henning\|Coutelle, Oliver\|Hacker, Ulrich
PMID:	18787354

685.
Journal:	Mol Cancer Ther. 2008 Sep;7(9):3103-11.
Title:	Polyethylene glycol-mediated colorectal cancer chemoprevention: roles of epidermal growth factor receptor and Snail.
Author:	Wali, Ramesh K\|Kunte, Dhananjay P\|Koetsier, Jennifer L\|Bissonnette, Marc\|Roy, Hemant K
PMID:	18790788

686.
Journal:	Clin Cancer Res. 2008 Sep 15;14(18):5869-76.
Title:	Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study.
Author:	Personeni, Nicola\|Fieuws, Steffen\|Piessevaux, Hubert\|De Hertogh, Gert\|De Schutter, Jef\|Biesmans, Bart\|De Roock, Wendy\|Capoen, An\|Debiec-Rychter, Maria\|Van Laethem, Jean-Luc\|Peeters, Marc\|Humblet, Yves\|Van Cutsem, Eric\|Tejpar, Sabine
PMID:	18794099

687.
Journal:	Oncogene. 2008 Dec 4;27(53):6729-37.
Title:	Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.
Author:	Liu, Y\|Borchert, G L\|Surazynski, A\|Phang, J M
PMID:	18794809

688.
Journal:	Virchows Arch. 2008 Nov;453(5):417-31.
Title:	KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program.
Author:	van Krieken, J H J M\|Jung, A\|Kirchner, T\|Carneiro, F\|Seruca, R\|Bosman, F T\|Quirke, P\|Flejou, J F\|Plato Hansen, T\|de Hertogh, G\|Jares, P\|Langner, C\|Hoefler, G\|Ligtenberg, M\|Tiniakos, D\|Tejpar, S\|Bevilacqua, G\|Ensari, A
PMID:	18802721

689.
Journal:	Pathologe. 2008 Nov;29 Suppl 2:200-3.
Title:	[Molecular targets for colon cancer. VEGF, EGFR - and what else?].
Author:	Rocken, C
PMID:	18810446

690.
Journal:	Cancer Res. 2008 Oct 1;68(19):8004-13.
Title:	Heterogeneity of receptor function in colon carcinoma cells determined by cross-talk between type I insulin-like growth factor receptor and epidermal growth factor receptor.
Author:	Hu, Yi Peter\|Patil, Sandip B\|Panasiewicz, Michelle\|Li, Wenhui\|Hauser, Jennie\|Humphrey, Lisa E\|Brattain, Michael G
PMID:	18829558

691.
Journal:	Cancer Res. 2008 Oct 15;68(20):8312-21.
Title:	Src and ADAM-17-mediated shedding of transforming growth factor-alpha is a mechanism of acute resistance to TRAIL.
Author:	Van Schaeybroeck, Sandra\|Kelly, Donal M\|Kyula, Joan\|Stokesberry, Susan\|Fennell, Dean A\|Johnston, Patrick G\|Longley, Daniel B
PMID:	18922903

692.
Journal:	Cell Oncol. 2008;30(6):463-71.
Title:	Tumour-associated transcripts and EGFR deletion variants in colorectal cancer in primary tumour, metastases and circulating tumour cells.
Author:	Lankiewicz, Silke\|Rother, Eva\|Zimmermann, Silke\|Hollmann, Christiane\|Korangy, Firouzeh\|Greten, Tim F
PMID:	18936523

693.
Journal:	N Engl J Med. 2008 Oct 23;359(17):1834-6.
Title:	Targeting EGFR in colorectal cancer.
Author:	Messersmith, Wells A\|Ahnen, Dennis J
PMID:	18946069

694.
Journal:	Int J Oncol. 2008 Nov;33(5):1107-13.
Title:	Co-targeting the EGFR and IGF-IR with anti-EGFR monoclonal antibody ICR62 and the IGF-IR tyrosine kinase inhibitor NVP-AEW541 in colorectal cancer cells.
Author:	Cunningham, Matthew P\|Thomas, Hilary\|Marks, Christopher\|Green, Margaret\|Fan, Zhen\|Modjtahedi, Helmout
PMID:	18949375

695.
Journal:	Yonsei Med J. 2008 Oct 31;49(5):851-2.
Title:	Severe acneiform eruption induced by cetuximab (Erbitux).
Author:	Lee, Jung Eun\|Lee, Sang Ju\|Lee, Hee Jung\|Lee, Ju Hee\|Lee, Kwang Hoon
PMID:	18972607

696.
Journal:	Pharmacotherapy. 2008 Nov;28(11 Pt 2):18S-22S.
Title:	Systemic therapy for advanced or metastatic colorectal cancer: National Comprehensive Cancer Network guidelines for combining anti-vascular endothelial growth factor and anti-epidermal growth factor receptor monoclonal antibodies with chemotherapy.
Author:	Engstrom, Paul F
PMID:	18980548

697.
Journal:	Biochem Biophys Res Commun. 2008 Dec 26;377(4):1118-22.
Title:	Enhanced antitumor activities of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives in vitro and in vivo.
Author:	Matsumura, Kazuaki\|Kaihatsu, Kunihiro\|Mori, Shuichi\|Cho, Han Hee\|Kato, Nobuo\|Hyon, Suong Hyu
PMID:	18983978

698.
Journal:	Clin Radiol. 2008 Dec;63(12):1372-9.
Title:	CT staging of colon cancer.
Author:	Dighe, S\|Swift, I\|Brown, G
PMID:	18996269

699.
Journal:	BioDrugs. 2008;22(6):403-11.
Title:	Panitumumab: in metastatic colorectal cancer with wild-type KRAS.
Author:	Weber, Juliane\|McCormack, Paul L
PMID:	18998757

700.
Journal:	J Clin Oncol. 2008 Dec 10;26(35):5668-70.
Title:	Using predictive biomarkers to select patients with advanced colorectal cancer for treatment with epidermal growth factor receptor antibodies.
Author:	Wong, Rachel\|Cunningham, David
PMID:	19001346

701.
Journal:	Bull Cancer. 2008 Oct;95(10):931-4.
Title:	[Is it possible to individualize prescription of medical treatment in colorectal cancer? The clinician point of view].
Author:	Ducreux, Michel\|Boige, Valerie\|Malka, David\|Laurent-Puig, Pierre
PMID:	19004722

702.
Journal:	Bull Cancer. 2008 Oct;95(10):935-42.
Title:	[The biological point of view on pharmacogenetics of anticancer agents in colorectal cancer].
Author:	Laurent-Puig, Pierre\|Lievre, Astrid\|Ducreux, Michel\|Loriot, Marie-Anne
PMID:	19004723

703.
Journal:	Bull Cancer. 2008 Oct;95(10):1003-5.
Title:	[Design of new protocols. Role of molecular biology units?].
Author:	Milano, Gerard
PMID:	19004733

704.
Journal:	Clin Cancer Res. 2008 Nov 15;14(22):7413-22.
Title:	Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer.
Author:	Manning, H Charles\|Merchant, Nipun B\|Foutch, A Coe\|Virostko, John M\|Wyatt, Shelby K\|Shah, Chirayu\|McKinley, Eliot T\|Xie, Jingping\|Mutic, Nathan J\|Washington, M Kay\|LaFleur, Bonnie\|Tantawy, Mohammed Noor\|Peterson, Todd E\|Ansari, M Sib\|Baldwin, Ronald M\|Rot
PMID:	19010858

705.
Journal:	J Exp Clin Cancer Res. 2008 Nov 12;27:69.
Title:	Id-1: regulator of EGFR and VEGF and potential target for colorectal cancer therapy.
Author:	Meteoglu, Ibrahim\|Meydan, Nezih\|Erkus, Muhan
PMID:	19014499

706.
Journal:	Int J Mol Med. 2008 Dec;22(6):847-51.
Title:	Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-alpha in colon cancer cells in vitro and in vivo.
Author:	Su, Chin-Cheng\|Lin, Yi-Hsiang
PMID:	19020785

707.
Journal:	Onkologie. 2008;31 Suppl 5:1-2.
Title:	[Colorectal carcinoma--molecular markers in clinical routine].
Author:	Tannapfel, Andrea\|Reinacher-Schick, Anke
PMID:	19033696

708.
Journal:	Clin Cancer Res. 2008 Dec 1;14(23):7884-95.
Title:	Polymorphisms in cyclooxygenase-2 and epidermal growth factor receptor are associated with progression-free survival independent of K-ras in metastatic colorectal cancer patients treated with single-agent cetuximab.
Author:	Lurje, Georg\|Nagashima, Fumio\|Zhang, Wu\|Yang, Dongyun\|Chang, Heung M\|Gordon, Michael A\|El-Khoueiry, Anthony\|Husain, Hatim\|Wilson, Peter M\|Ladner, Robert D\|Mauro, David J\|Langer, Christiane\|Rowinsky, Eric K\|Lenz, Heinz-Josef
PMID:	19047118

709.
Journal:	Clin Colorectal Cancer. 2008 Dec;7 Suppl 2:S52-7.
Title:	Understanding the predictive role of K-ras for epidermal growth factor receptor-targeted therapies in colorectal cancer.
Author:	Ramos, Francisco Javier\|Macarulla, Teresa\|Capdevila, Jaume\|Elez, Elena\|Tabernero, Josep
PMID:	19064407

710.
Journal:	Recent Pat Biotechnol. 2008;2(3):181-7.
Title:	ErbB antagonists patenting: "playing chess with cancer".
Author:	Aifa, Sami\|Rebai, Ahmed
PMID:	19075865

711.
Journal:	Br J Cancer. 2008 Dec 16;99(12):2100.
Title:	KRAS mutation status in colorectal cancer to predict response to EGFR targeted therapies: the need for a more precise definition.
Author:	Rouleau, E\|Spyratos, F\|Dieumegard, B\|Guinebretiere, J M\|Lidereau, R\|Bieche, I
PMID:	19078954

712.
Journal:	Histopathology. 2008 Dec;53(6):698-706.
Title:	EGFR, HER-2 and COX-2 levels in colorectal cancer.
Author:	Antonacopoulou, A G\|Tsamandas, A C\|Petsas, T\|Liava, A\|Scopa, C D\|Papavassiliou, A G\|Kalofonos, H P
PMID:	19102009

713.
Journal:	Curr Treat Options Oncol. 2008 Dec;9(4-6):357-74.
Title:	The role of targeted therapy in the treatment of advanced colorectal cancer.
Author:	Fakih, Marwan
PMID:	19238551

714.
Journal:	Gastrointest Cancer Res. 2008 May;2(3):145-51.
Title:	Rationale for combining biotherapy in the treatment of advanced colon cancer.
Author:	Cohen, Deirdre J\|Hochster, Howard S
PMID:	19259292

715.
Journal:	Gastrointest Cancer Res. 2008 Jul;2(4 Suppl):S20-2.
Title:	Colorectal Cancer Treatment: What's Next? (or: Is There Life After EGFR and VEGF?).
Author:	Saltz, Leonard
PMID:	19343143

716.
Journal:	Clin Adv Hematol Oncol. 2008 Dec;6(12):1-13, 14-6.
Title:	KRAS mutation in metastatic colorectal cancer and its impact on the use of EGFR inhibitors.
Author:	Lenz, Heinz-Josef\|Chu, Edward\|Grothey, Axel
PMID:	19378369

717.
Journal:	Biologics. 2008 Jun;2(2):223-8.
Title:	Targeting colorectal cancer with human anti-EGFR monoclonocal antibodies: focus on panitumumab.
Author:	Kim, George P\|Grothey, Axel
PMID:	19707356

718.
Journal:	Gene Regul Syst Bio. 2008 May 2;2:163-176.
Title:	Multi-Target Approaches in Colon Cancer Chemoprevention Based on Systems Biology of Tumor Cell-Signaling.
Author:	Guruswamy, Suresh\|Rao, Chinthalapally V
PMID:	19763245

719.
Journal:	Proteomics Clin Appl. 2008 Jun;2(6):908-14.
Title:	Cetuximab inhibits thymidylate synthase in colorectal cells expressing epidermal growth factor receptor.
Author:	Skvortsov, Sergej\|Sarg, Bettina\|Lindner, Herbert\|Lukas, Peter\|Hilbe, Wolfgang\|Zwierzina, Heinz\|Skvortsova, Ira
PMID:	21136888

720.
Journal:	Cancer Detect Prev. 2009;32(4):329-35. Epub 2006 May 2.
Title:	Mutant p53 protein in the serum of patients with colorectal cancer: Correlation with the level of carcinoembryonic antigen and serum epidermal growth factor receptor.
Author:	Abdel-Aziz, Mohamed M\|Lotfy, Mahmoud\|El-Kady, Ibrahim M\|Abozaid, Mostafa
PMID:	16632243

721.
Journal:	Ann Oncol. 2009 Jan;20(1):84-90.
Title:	PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients.
Author:	Perrone, F\|Lampis, A\|Orsenigo, M\|Di Bartolomeo, M\|Gevorgyan, A\|Losa, M\|Frattini, M\|Riva, C\|Andreola, S\|Bajetta, E\|Bertario, L\|Leo, E\|Pierotti, M A\|Pilotti, S
PMID:	18669866

722.
Journal:	Cancer Chemother Pharmacol. 2009 May;63(6):973-81.
Title:	Dual targeting of EGFR and HER-2 in colon cancer cell lines.
Author:	Giannopoulou, Efstathia\|Antonacopoulou, Anna\|Floratou, Konstantina\|Papavassiliou, Athanasios G\|Kalofonos, Haralabos P
PMID:	18751705

723.
Journal:	Cancer Lett. 2009 Jan 18;273(2):225-32.
Title:	Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression.
Author:	Al-Salihi, Mazin A\|Terrece Pearman, A\|Doan, Thao\|Reichert, Ethan C\|Rosenberg, Daniel W\|Prescott, Stephen M\|Stafforini, Diana M\|Topham, Matthew K
PMID:	18790560

724.
Journal:	Biochem Biophys Res Commun. 2009 Jan 16;378(3):344-7.
Title:	Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer.
Author:	Patel, Bhaumik B\|Yu, Yingjie\|Du, Jianhua\|Levi, Edi\|Phillip, Phillip A\|Majumdar, Adhip P N
PMID:	19010307

725.
Journal:	Oncology. 2009;76(1):42-8.
Title:	Relationships of insulin-like growth factor-1 receptor and epidermal growth factor receptor expression to clinical outcomes in patients with colorectal cancer.
Author:	Takahari, Daisuke\|Yamada, Yasuhide\|Okita, Natuko T\|Honda, Takuya\|Hirashima, Yoshinori\|Matsubara, Junichi\|Takashima, Atsuo\|Kato, Ken\|Hamaguchi, Tetsuya\|Shirao, Kuniaki\|Shimada, Yasuhiro\|Shimoda, Tadakazu
PMID:	19033715

726.
Journal:	Carcinogenesis. 2009 Feb;30(2):300-7.
Title:	A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways.
Author:	Suh, Yewseok\|Afaq, Farrukh\|Johnson, Jeremy J\|Mukhtar, Hasan
PMID:	19037088

727.
Journal:	Am J Surg Pathol. 2009 Apr;33(4):572-82.
Title:	Clinical, pathologic, and molecular features of early-onset colorectal carcinoma.
Author:	Yantiss, Rhonda K\|Goodarzi, Mahmoud\|Zhou, Xi K\|Rennert, Hanna\|Pirog, Edyta C\|Banner, Barbara F\|Chen, Yao-Tseng
PMID:	19047896

728.
Journal:	Int J Colorectal Dis. 2009 Feb;24(2):129-38.
Title:	Molecular and clinico-pathological markers in rectal cancer: a tissue micro-array study.
Author:	Debucquoy, Annelies\|Goethals, Laurence\|Libbrecht, Louis\|Perneel, Christiaan\|Geboes, Karel\|Ectors, Nadine\|McBride, William H\|Haustermans, Karin
PMID:	19050903

729.
Journal:	Exp Cell Res. 2009 Feb 1;315(3):432-50.
Title:	Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis.
Author:	Shant, Jasleen\|Cheng, Kunrong\|Marasa, Bernard S\|Wang, Jian-Ying\|Raufman, Jean-Pierre
PMID:	19056378

730.
Journal:	Int J Cancer. 2009 Apr 1;124(7):1517-25.
Title:	Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase.
Author:	Gratio, Valerie\|Walker, Francine\|Lehy, Therese\|Laburthe, Marc\|Darmoul, Dalila
PMID:	19058300

731.
Journal:	Cancer Treat Rev. 2009 May;35(3):262-71.
Title:	Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR.
Author:	Heinemann, Volker\|Stintzing, Sebastian\|Kirchner, Thomas\|Boeck, Stefan\|Jung, Andreas
PMID:	19117687

732.
Journal:	Eur J Cancer. 2009 May;45(7):1117-28.
Title:	Resistance to EGF-R (erbB-1) and VEGF-R modulating agents.
Author:	Dempke, Wolfram C M\|Heinemann, Volker
PMID:	19124237

733.
Journal:	Cancer Lett. 2009 May 8;277(1):108-13.
Title:	p38 MAP kinase controls EGF receptor downregulation via phosphorylation at Ser1046/1047.
Author:	Adachi, Seiji\|Natsume, Hideo\|Yamauchi, Junichi\|Matsushima-Nishiwaki, Rie\|Joe, Andrew K\|Moriwaki, Hisataka\|Kozawa, Osamu
PMID:	19138820

734.
Journal:	Oncologist. 2009 Jan;14(1):29-39.
Title:	Anti-epidermal growth factor receptor monotherapy in the treatment of metastatic colorectal cancer: where are we today?
Author:	Peeters, Marc\|Price, Tim\|Van Laethem, Jean-Luc
PMID:	19144681

735.
Journal:	Gan To Kagaku Ryoho. 2009 Jan;36(1):11-4.
Title:	[Biomarker for chemotherapy in patients with colorectal cancer].
Author:	Matsusaka, Satoshi
PMID:	19151559

736.
Journal:	J Clin Oncol. 2009 Apr 20;27(12):2091-6.
Title:	American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy.
Author:	Allegra, Carmen J\|Jessup, J Milburn\|Somerfield, Mark R\|Hamilton, Stanley R\|Hammond, Elizabeth H\|Hayes, Daniel F\|McAllister, Pamela K\|Morton, Roscoe F\|Schilsky, Richard L
PMID:	19188670

737.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G755-63.
Title:	Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells.
Author:	Xie, Guofeng\|Cheng, Kunrong\|Shant, Jasleen\|Raufman, Jean-Pierre
PMID:	19221016

738.
Journal:	Cancer Res. 2009 Mar 1;69(5):1851-7.
Title:	PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
Author:	Sartore-Bianchi, Andrea\|Martini, Miriam\|Molinari, Francesca\|Veronese, Silvio\|Nichelatti, Michele\|Artale, Salvatore\|Di Nicolantonio, Federica\|Saletti, Piercarlo\|De Dosso, Sara\|Mazzucchelli, Luca\|Frattini, Milo\|Siena, Salvatore\|Bardelli, Alberto
PMID:	19223544

739.
Journal:	Strahlenther Onkol. 2009 Jan;185(1):8-18.
Title:	Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Author:	Niyazi, Maximilian\|Marini, Patrizia\|Daniel, Peter T\|Humphreys, Robin\|Jendrossek, Verena\|Belka, Claus
PMID:	19224142

740.
Journal:	Curr Oncol. 2009 Jan;16(1):16-26.
Title:	Management of skin rash during EGFR-targeted monoclonal antibody treatment for gastrointestinal malignancies: Canadian recommendations.
Author:	Melosky, B\|Burkes, R\|Rayson, D\|Alcindor, T\|Shear, N\|Lacouture, M
PMID:	19229368

741.
Journal:	J Cell Biochem. 2009 Apr 15;106(6):1113-22.
Title:	Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.
Author:	Lee, Dae-Hee\|Szczepanski, Miroslaw-Jerzy\|Lee, Yong J
PMID:	19229860

742.
Journal:	Inflamm Bowel Dis. 2009 Jul;15(7):997-1006.
Title:	Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors.
Author:	Fukata, Masayuki\|Hernandez, Yasmin\|Conduah, Daisy\|Cohen, Jason\|Chen, Anli\|Breglio, Keith\|Goo, Tyralee\|Hsu, David\|Xu, Ruliang\|Abreu, Maria T
PMID:	19229991

743.
Journal:	Rev Med Interne. 2009 May;30(5):411-5.
Title:	[What are the new therapeutic strategies in metastatic colorectal cancer including biotherapies?].
Author:	Tournigand, C\|Bengrine-Lefevre, L
PMID:	19231039

744.
Journal:	Clin Chem. 2009 Apr;55(4):748-56.
Title:	Coamplification at lower denaturation temperature-PCR increases mutation-detection selectivity of TaqMan-based real-time PCR.
Author:	Li, Jin\|Wang, Lilin\|Janne, Pasi A\|Makrigiorgos, G Mike
PMID:	19233916

745.
Journal:	J Hematol Oncol. 2009 Feb 23;2:9.
Title:	Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology.
Author:	Javle, Milind\|Hsueh, Chung-Tsen
PMID:	19236713

746.
Journal:	J Clin Oncol. 2009 Apr 10;27(11):1822-8.
Title:	Health-related quality of life in patients with advanced colorectal cancer treated with cetuximab: overall and KRAS-specific results of the NCIC CTG and AGITG CO.17 Trial.
Author:	Au, Heather-Jane\|Karapetis, Christos S\|O'Callaghan, Chris J\|Tu, Dongsheng\|Moore, Malcolm J\|Zalcberg, John R\|Kennecke, Hagen\|Shapiro, Jeremy D\|Koski, Sheryl\|Pavlakis, Nick\|Charpentier, Danielle\|Wyld, David\|Jefford, Michael\|Knight, Gregory J\|Magoski, Nadine
PMID:	19273701

747.
Journal:	Clin Adv Hematol Oncol. 2009 Jan;7(1):45-53, 64.
Title:	K-ras mutations in colorectal cancer: a practice changing discovery.
Author:	Saif, M Wasif\|Shah, Manasi
PMID:	19274041

748.
Journal:	Clin Cancer Res. 2009 Apr 1;15(7):2397-405.
Title:	Dose-dependent increases in circulating TGF-alpha and other EGFR ligands act as pharmacodynamic markers for optimal biological dosing of cetuximab and are tumor independent.
Author:	Mutsaers, Anthony J\|Francia, Giulio\|Man, Shan\|Lee, Christina R\|Ebos, John M L\|Wu, Yan\|Witte, Larry\|Berry, Scott\|Moore, Malcolm\|Kerbel, Robert S
PMID:	19276250

749.
Journal:	Br J Cancer. 2009 Apr 7;100(7):1120-7.
Title:	Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib.
Author:	Lemos, C\|Kathmann, I\|Giovannetti, E\|Calhau, C\|Jansen, G\|Peters, G J
PMID:	19277036

750.
Journal:	Drug Resist Updat. 2009 Jun;12(3):55-64.
Title:	Targeting apoptosis as an approach for gastrointestinal cancer therapy.
Author:	Qiao, Liang\|Wong, Benjamin C Y
PMID:	19278896

751.
Journal:	Eur J Gastroenterol Hepatol. 2009 Mar;21(3):289-93.
Title:	Human epidermal growth factor receptor-2 family in colorectal adenocarcinoma: correlation with survival and clinicopathological findings.
Author:	Molaei, Mahsa\|Pejhan, Shervin\|Nayer, Babak Noori\|Moradi, Afshin\|Ghiasi, Somaye\|Zali, Mohamad Reza
PMID:	19279475

752.
Journal:	Br J Cancer. 2009 Apr 7;100(7):1087-94.
Title:	Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant.
Author:	Molinari, F\|Martin, V\|Saletti, P\|De Dosso, S\|Spitale, A\|Camponovo, A\|Bordoni, A\|Crippa, S\|Mazzucchelli, L\|Frattini, M
PMID:	19293803

753.
Journal:	Neoplasma. 2009;56(3):275-8.
Title:	Genetic analysis of KRAS mutation status in metastatic colorectal cancer patients.
Author:	Zavodna, K\|Konecny, M\|Krivulcik, T\|Spanik, S\|Behulova, R\|Vizvaryova, M\|Weismanova, E\|Galbavy, S\|Kausitz, J
PMID:	19309232

754.
Journal:	Bull Cancer. 2009 Mar;96(3):321-8.
Title:	[Neoadjuvant approach for non-metastatic rectal cancer combining radiotherapy and chemotherapy. Biotargeted drugs].
Author:	Gerard, J-P\|Francois, E\|Deustch, E\|Rostom, Y\|Douar, N\|Benezery, K\|Milano, G
PMID:	19318310

755.
Journal:	Anticancer Res. 2009 Jan;29(1):229-34.
Title:	Expression of ErbB receptors and their cognate ligands in gastric and colon cancer cell lines.
Author:	Wu, William Ka Kei\|Tse, Timothy Tim Ming\|Sung, Joseph Jao Yiu\|Li, Zhi Jie\|Yu, Le\|Cho, Chi Hin
PMID:	19331154

756.
Journal:	Anticancer Res. 2009 Feb;29(2):785-91.
Title:	P53 and EGFR expression in colorectal cancer: a reappraisal of 'old' tissue markers in patients with long follow-up.
Author:	Theodoropoulos, George E\|Karafoka, Eleni\|Papailiou, Joanna G\|Stamopoulos, Paraskevas\|Zambirinis, Constantinos P\|Bramis, Konstantinos\|Panoussopoulos, Sotirios-George\|Leandros, Emmanouil\|Bramis, John
PMID:	19331236

757.
Journal:	Nat Rev Clin Oncol. 2009 Apr;6(4):207-18.
Title:	Toxic effects and their management: daily clinical challenges in the treatment of colorectal cancer.
Author:	Eng, Cathy
PMID:	19333227

758.
Journal:	J Cancer Res Clin Oncol. 2009 Oct;135(10):1377-86.
Title:	Antitumor activity of the HER2 dimerization inhibitor pertuzumab on human colon cancer cells in vitro and in vivo.
Author:	Pohl, Michael\|Stricker, I\|Schoeneck, A\|Schulmann, K\|Klein-Scory, S\|Schwarte-Waldhoff, I\|Hasmann, M\|Tannapfel, A\|Schmiegel, W\|Reinacher-Schick, A
PMID:	19340455

759.
Journal:	Am J Ther. 2009 Nov-Dec;16(6):554-61.
Title:	KRAS mutational status as a predictor of epidermal growth factor receptor inhibitor efficacy in colorectal cancer.
Author:	Baynes, Roy D\|Gansert, Jennifer
PMID:	19352138

760.
Journal:	BMC Cancer. 2009 Apr 9;9:111.
Title:	KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay.
Author:	Auner, Veronika\|Kriegshauser, Gernot\|Tong, Dan\|Horvat, Reinhard\|Reinthaller, Alexander\|Mustea, Alexander\|Zeillinger, Robert
PMID:	19358724

761.
Journal:	Oncol Rep. 2009 May;21(5):1161-8.
Title:	No functional and transductional significance of specific neuropilin 1 siRNA inhibition in colon carcinoma cell lines lacking VEGF receptor 2.
Author:	Quante, Michael\|Raskopf, Esther\|Stahl, Sebastian\|Vogt, Annabelle\|Sauerbruch, Tilman\|Schmitz, Volker
PMID:	19360289

762.
Journal:	Med Sci (Paris). 2009 Mar;25 Spec No 1:7-8.
Title:	[Towards an individualized treatment of the colorectal cancer: a new therapy against EGFR opens the way].
Author:	Sylviane, Olschwang
PMID:	19361403

763.
Journal:	Med Sci (Paris). 2009 Mar;25 Spec No 1:13-21.
Title:	[Metastatic colorectal cancers and targeted therapy against EGFR].
Author:	Viret, Frederic\|Goncalves, Anthony
PMID:	19361405

764.
Journal:	Expert Opin Biol Ther. 2009 May;9(5):565-77.
Title:	KRAS mutations and sensitivity to anti-EGFR monoclonal antibodies in metastatic colorectal carcinoma: an open issue.
Author:	Silvestris, Nicola\|Tommasi, Stefania\|Santini, Daniele\|Russo, Antonio\|Simone, Gianni\|Petriella, Daniela\|Maiello, Evaristo\|Tonini, Giuseppe\|Colucci, Giuseppe
PMID:	19368524

765.
Journal:	BMC Mol Biol. 2009 Apr 15;10:31.
Title:	Reverse transcription-quantitative polymerase chain reaction: description of a RIN-based algorithm for accurate data normalization.
Author:	Ho-Pun-Cheung, Alexandre\|Bascoul-Mollevi, Caroline\|Assenat, Eric\|Boissiere-Michot, Florence\|Bibeau, Frederic\|Cellier, Dominic\|Ychou, Marc\|Lopez-Crapez, Evelyne
PMID:	19368728

766.
Journal:	Mol Cancer Ther. 2009 Apr;8(4):821-33.
Title:	Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis.
Author:	Kaulfuss, Silke\|Burfeind, Peter\|Gaedcke, Jochen\|Scharf, Jens-Gerd
PMID:	19372555

767.
Journal:	Head Neck. 2009 Aug;31(8):1086-94.
Title:	Mechanisms of resistance to EGFR inhibitors in head and neck cancer.
Author:	Cooper, Jonathan B\|Cohen, Ezra Eddy Wyssam
PMID:	19378324

768.
Journal:	Expert Opin Biol Ther. 2009 May;9(5):667-74.
Title:	Current situation of zalutumumab.
Author:	Rivera, Fernando\|Salcedo, Matilde\|Vega, Noelia\|Blanco, Yolanda\|Lopez, Carlos
PMID:	19379120

769.
Journal:	J Hematol Oncol. 2009 Apr 22;2:18.
Title:	Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy.
Author:	Chang, David Z\|Kumar, Vikas\|Ma, Ying\|Li, Kuiyuan\|Kopetz, Scott
PMID:	19386128

770.
Journal:	Int J Colorectal Dis. 2009 Sep;24(9):1059-68.
Title:	ErbB family immunohistochemical expression in colorectal cancer patients with higher risk of recurrence after radical surgery.
Author:	Baiocchi, Glauco\|Lopes, Ademar\|Coudry, Renata A\|Rossi, Benedito M\|Soares, Fernando A\|Aguiar, Samuel\|Guimaraes, Gustavo C\|Ferreira, Fabio O\|Nakagawa, Wilson T
PMID:	19390858

771.
Journal:	Pathology. 2009;41(4):356-60.
Title:	Immunohistochemical expression of EGFR in colorectal carcinoma correlates with high but not low level gene amplification, as demonstrated by CISH.
Author:	Hemmings, Chris\|Broomfield, Amy\|Bean, Elaine\|Whitehead, Martin\|Yip, Desmond
PMID:	19404848

772.
Journal:	Clin Colorectal Cancer. 2009 Mar;8(2):110-7.
Title:	Multiplexed Cell Signaling Analysis of Metastatic and Nonmetastatic Colorectal Cancer Reveals COX2-EGFR Signaling Activation as a Potential Prognostic Pathway Biomarker.
Author:	Pierobon, Mariaelena\|Calvert, Valerie\|Belluco, Claudio\|Garaci, Enrico\|Deng, Jianghong\|Lise, Mario\|Nitti, Donato\|Mammano, Enzo\|Marchi, Francesco De\|Liotta, Lance\|Petricoin, Emanuel
PMID:	19423505

773.
Journal:	Br J Cancer. 2009 Jun 2;100(11):1704-19.
Title:	Treatment in advanced colorectal cancer: what, when and how?
Author:	Chau, I\|Cunningham, D
PMID:	19436303

774.
Journal:	Mol Nutr Food Res. 2009 Jun;53(6):686-98.
Title:	Gene expression, cell cycle arrest and MAPK signalling regulation in Caco-2 cells exposed to ellagic acid and its metabolites, urolithins.
Author:	Gonzalez-Sarrias, Antonio\|Espin, Juan-Carlos\|Tomas-Barberan, Francisco A\|Garcia-Conesa, Maria-Teresa
PMID:	19437480

775.
Journal:	BMC Cancer. 2009 May 13;9:145.
Title:	A gene expression predictor of response to EGFR-targeted therapy stratifies progression-free survival to cetuximab in KRAS wild-type metastatic colorectal cancer.
Author:	Balko, Justin M\|Black, Esther P
PMID:	19439077

776.
Journal:	Anticancer Res. 2009 May;29(5):1489-94.
Title:	ErbB 1-4 expression alterations in primary colorectal cancers and their corresponding metastases.
Author:	Ljuslinder, Ingrid\|Malmer, Beatrice\|Isaksson-Mettavainio, Martin\|Oberg, Ake\|Henriksson, Roger\|Stenling, Roger\|Palmqvist, Richard
PMID:	19443355

777.
Journal:	J Chromatogr A. 2009 Jun 26;1216(26):5147-54.
Title:	Genotyping of K-ras codons 12 and 13 mutations in colorectal cancer by capillary electrophoresis.
Author:	Chen, Yen-Ling\|Chang, Ya-Sian\|Chang, Jan-Gowth\|Wu, Shou-Mei
PMID:	19450806

778.
Journal:	Am J Clin Oncol. 2009 Jun;32(3):245-52.
Title:	High epidermal growth factor receptor expression in metastatic colorectal cancer lymph nodes may be more prognostic of poor survival than in primary tumor.
Author:	Deng, Yanhong\|Kurland, Brenda F\|Wang, Jianping\|Bi, Jiong\|Li, Wen\|Rao, Sujata\|Lan, Ping\|Lin, Tongyu\|Lin, Edward
PMID:	19451802

779.
Journal:	Target Oncol. 2009 Apr;4(2):107-19.
Title:	Skin toxicities associated with epidermal growth factor receptor inhibitors.
Author:	Li, Tianhong\|Perez-Soler, Roman
PMID:	19452131

780.
Journal:	Biochem Biophys Res Commun. 2009 Jul 31;385(3):430-3.
Title:	Combination of aging and dimethylhydrazine treatment causes an increase in cancer-stem cell population of rat colonic crypts.
Author:	Levi, Edi\|Misra, Sandhya\|Du, Jianhua\|Patel, Bhaumik B\|Majumdar, Adhip P N
PMID:	19465005

781.
Journal:	Dtsch Arztebl Int. 2009 Mar;106(12):202-6.
Title:	The treatment of colorectal carcinoma with monoclonal antibodies: the importance of KRAS mutation analysis and EGFR status.
Author:	Stintzing, Sebastian\|Heinemann, Volker\|Moosmann, Nicolas\|Hiddemann, Wolfgang\|Jung, Andreas\|Kirchner, Thomas
PMID:	19471640

782.
Journal:	Cell Oncol. 2009;31(3):161-7.
Title:	A fast, sensitive and accurate high resolution melting (HRM) technology-based assay to screen for common K-ras mutations.
Author:	Kramer, D\|Thunnissen, F B\|Gallegos-Ruiz, M I\|Smit, E F\|Postmus, P E\|Meijer, C J L M\|Snijders, P J F\|Heideman, D A M
PMID:	19478384

783.
Journal:	Curr Opin Mol Ther. 2009 Jun;11(3):308-21.
Title:	Tyrosine kinase inhibitors - small molecular weight compounds inhibiting EGFR.
Author:	Hegymegi-Barakonyi, Balint\|Eros, Daniel\|Szantai-Kis, Csaba\|Breza, Nora\|Banhegyi, Peter\|Szabo, Gabor Viktor\|Varkondi, Edit\|Petak, Istvan\|Orfi, Laszlo\|Keri, Gyorgy
PMID:	19479664

784.
Journal:	Int J Radiat Oncol Biol Phys. 2009 Jul 1;74(3):673-88.
Title:	Biomarkers for response to neoadjuvant chemoradiation for rectal cancer.
Author:	Kuremsky, Jeffrey G\|Tepper, Joel E\|McLeod, Howard L
PMID:	19480968

785.
Journal:	Gastroenterology. 2009 Sep;137(3):914-23.
Title:	Saccharomyces boulardii inhibits EGF receptor signaling and intestinal tumor growth in Apc(min) mice.
Author:	Chen, Xinhua\|Fruehauf, Johannes\|Goldsmith, Jeffrey D\|Xu, Hua\|Katchar, Kianoosh K\|Koon, Hon-Wai\|Zhao, Dezheng\|Kokkotou, Efi G\|Pothoulakis, Charalabos\|Kelly, Ciaran P
PMID:	19482027

786.
Journal:	Nat Rev Clin Oncol. 2009 Jun;6(6):306-7.
Title:	Genetics: Predictive value of KRAS mutations in chemoresistant CRC.
Author:	Lievre, Astrid\|Laurent-Puig, Pierre
PMID:	19483733

787.
Journal:	Strahlenther Onkol. 2009 Jun;185(6):371-8.
Title:	Molecular targeted treatment and radiation therapy for rectal cancer.
Author:	Marquardt, Friederike\|Rodel, Franz\|Capalbo, Gianni\|Weiss, Christian\|Rodel, Claus
PMID:	19506820

788.
Journal:	J Cutan Pathol. 2009 Dec;36(12):1303-7.
Title:	A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib.
Author:	Pongpudpunth, Marinya\|Demierre, Marie France\|Goldberg, Lynne J
PMID:	19519875

789.
Journal:	J Surg Res. 2009 Oct;156(2):250-6.
Title:	The effects of epidermal growth factor receptor activation and attenuation of the TGFbeta pathway in an orthotopic model of colon cancer.
Author:	Ongchin, Melanie\|Sharratt, Elizabeth\|Dominguez, Ivan\|Simms, Neka\|Wang, Jing\|Cheney, Richard\|LeVea, Charles\|Brattain, Michael\|Rajput, Ashwani
PMID:	19524264

790.
Journal:	Cancer. 2009 Aug 15;115(16):3609-17.
Title:	Assessment of K-ras mutation: a step toward personalized medicine for patients with colorectal cancer.
Author:	Jiang, Yixing\|Kimchi, Eric T\|Staveley-O'Carroll, Kevin F\|Cheng, Hua\|Ajani, Jaffer A
PMID:	19526592

791.
Journal:	Anticancer Res. 2009 Jun;29(6):1999-2007.
Title:	Prioritization of EGFR/IGF-IR/VEGFR2 combination targeted therapies utilizing cancer models.
Author:	Tonra, James R\|Corcoran, Erik\|Deevi, Dhanvanthri S\|Steiner, Philipp\|Kearney, Jessica\|Li, Huiling\|Ludwig, Dale L\|Zhu, Zhenping\|Witte, Larry\|Surguladze, David\|Hicklin, Daniel J
PMID:	19528458

792.
Journal:	J Pak Med Assoc. 2009 Jun;59(6):398-405.
Title:	Old disease, new targets--part-I, solid malignancies.
Author:	Kumar, Shiyam\|Masood, Nehal\|Shaikh, Asim Jamal
PMID:	19534378

793.
Journal:	Expert Opin Biol Ther. 2009 Aug;9(8):945-9.
Title:	Cigarettes smoking habit may reduce benefit from cetuximab-based treatment in advanced colorectal cancer patients.
Author:	Vincenzi, Bruno\|Santini, Daniele\|Loupakis, Fotios\|Addeo, Raffaele\|Rojas Llimpe, Fabiola L\|Baldi, Giacomo Giulio\|Di Fabio, Francesca\|Del Prete, Salvatore\|Pinto, Carmine\|Falcone, Alfredo\|Tonini, Giuseppe
PMID:	19534585

794.
Journal:	Nat Rev Cancer. 2009 Jul;9(7):489-99.
Title:	Genetic prognostic and predictive markers in colorectal cancer.
Author:	Walther, Axel\|Johnstone, Elaine\|Swanton, Charles\|Midgley, Rachel\|Tomlinson, Ian\|Kerr, David
PMID:	19536109

795.
Journal:	Int J Cancer. 2009 Dec 15;125(12):2957-69.
Title:	The dual EGFR/HER-2 tyrosine kinase inhibitor lapatinib sensitizes colon and gastric cancer cells to the irinotecan active metabolite SN-38.
Author:	LaBonte, Melissa J\|Manegold, Philipp C\|Wilson, Peter M\|Fazzone, Will\|Louie, Stan G\|Lenz, Heinz-Josef\|Ladner, Robert D
PMID:	19536776

796.
Journal:	Mol Diagn Ther. 2009;13(2):103-14.
Title:	Clinical biomarkers in oncology: focus on colorectal cancer.
Author:	De Roock, Wendy\|Biesmans, Bart\|De Schutter, Jef\|Tejpar, Sabine
PMID:	19537845

797.
Journal:	Gan To Kagaku Ryoho. 2009 Jun;36(6):1003-6.
Title:	[Two cases of KRAS wild-type unresectable or recurrent colorectal cancer effectively treated by cetuximab after progression of prior chemotherapy].
Author:	Yoda, Yusuke\|Yoshino, Takayuki\|Kadowaki, Shigenori\|Bando, Hideaki\|Okano, Susumu\|Fukushima, Hiraku\|Fuse, Nozomu\|Tahara, Makoto\|Doi, Toshihiko\|Ohtsu, Atsushi
PMID:	19542725

798.
Journal:	Adv Anat Pathol. 2009 Jul;16(4):196-203.
Title:	KRAS mutation testing in colorectal cancer.
Author:	Plesec, Thomas P\|Hunt, Jennifer L
PMID:	19546608

799.
Journal:	BMC Cancer. 2009 Jun 26;9:207.
Title:	Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.
Author:	Doherty, Glen A\|Byrne, Sinead M\|Molloy, Eamonn S\|Malhotra, Vikrum\|Austin, Sandra C\|Kay, Elaine W\|Murray, Frank E\|Fitzgerald, Desmond J
PMID:	19558693

800.
Journal:	Carcinogenesis. 2009 Sep;30(9):1544-52.
Title:	(-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.
Author:	Adachi, Seiji\|Shimizu, Masahito\|Shirakami, Yohei\|Yamauchi, Junichi\|Natsume, Hideo\|Matsushima-Nishiwaki, Rie\|To, Satoshi\|Weinstein, I Bernard\|Moriwaki, Hisataka\|Kozawa, Osamu
PMID:	19578043

801.
Journal:	Magy Onkol. 2009 Jun;53(2):135-42.
Title:	[Panitumumab-treatment of metastatic colorectal cancer].
Author:	Piko, Bela
PMID:	19581179

802.
Journal:	JOP. 2009 Jul 6;10(4):357-60.
Title:	Pharmacogenetics in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009.
Author:	Strimpakos, Alexios S\|Syrigos, Kostas N\|Saif, Muhammad Wasif
PMID:	19581734

803.
Journal:	Clin Cancer Res. 2009 Jul 15;15(14):4531-7.
Title:	Down-regulation of epidermal growth factor receptor by selective expansion of a 5'-end regulatory dinucleotide repeat in colon cancer with microsatellite instability.
Author:	Baranovskaya, Svetlana\|Martin, Yolanda\|Alonso, Sergio\|Pisarchuk, Ksenia L\|Falchetti, Mario\|Dai, Yuichi\|Khaldoyanidi, Sophia\|Krajewski, Stan\|Novikova, Inna\|Sidorenko, Yuri S\|Perucho, Manuel\|Malkhosyan, Sergei R
PMID:	19584170

804.
Journal:	J Oncol. 2009;2009:849051.
Title:	Clinical Significance of Skin Toxicity due to EGFR-Targeted Therapies.
Author:	Giovannini, Monica\|Gregorc, Vanesa\|Belli, Carmen\|Roca, Elisa\|Lazzari, Chiara\|Vigano, Maria Grazia\|Serafico, Anna\|Villa, Eugenio
PMID:	19584908

805.
Journal:	Nat Rev Clin Oncol. 2009 Sep;6(9):528-34.
Title:	Are RAS mutations predictive markers of resistance to standard chemotherapy?
Author:	Loriot, Yohann\|Mordant, Pierre\|Deutsch, Eric\|Olaussen, Ken Andre\|Soria, Jean-Charles
PMID:	19597509

806.
Journal:	Br J Cancer. 2009 Aug 18;101(4):715-21.
Title:	KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.
Author:	Loupakis, F\|Ruzzo, A\|Cremolini, C\|Vincenzi, B\|Salvatore, L\|Santini, D\|Masi, G\|Stasi, I\|Canestrari, E\|Rulli, E\|Floriani, I\|Bencardino, K\|Galluccio, N\|Catalano, V\|Tonini, G\|Magnani, M\|Fontanini, G\|Basolo, F\|Falcone, A\|Graziano, F
PMID:	19603018

807.
Journal:	Biochem Biophys Res Commun. 2009 Sep 25;387(3):521-4.
Title:	Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells.
Author:	Jiang, Xiaohua\|Sinnett-Smith, James\|Rozengurt, Enrique
PMID:	19615971

808.
Journal:	Gan To Kagaku Ryoho. 2009 Jul;36(7):1063-6.
Title:	[Status of components in EGFR-related signal transduction as predictive markers for anti-EGFR antibody therapy in colorectal cancer treatment].
Author:	Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Ishioka, Chikashi
PMID:	19620792

809.
Journal:	Gan To Kagaku Ryoho. 2009 Jul;36(7):1203-12.
Title:	[Cetuximab (Erbitux)].
Author:	Shimoyama, Tatsu
PMID:	19620819

810.
Journal:	Clin Colorectal Cancer. 2009 Jul;8(3):135-40.
Title:	KRAS testing in metastatic colorectal cancer: implications on the use of biologic agents.
Author:	Bekaii-Saab, Tanios
PMID:	19632927

811.
Journal:	Nat Rev Clin Oncol. 2009 Sep;6(9):519-27.
Title:	Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.
Author:	Normanno, Nicola\|Tejpar, Sabine\|Morgillo, Floriana\|De Luca, Antonella\|Van Cutsem, Eric\|Ciardiello, Fortunato
PMID:	19636327

812.
Journal:	J Oncol. 2009;2009:804108.
Title:	Anti-EGFR-Targeted Therapy for Esophageal and Gastric Cancers: An Evolving Concept.
Author:	Dragovich, Tomislav\|Campen, Christopher
PMID:	19636422

813.
Journal:	J Oncol. 2009;2009:896407.
Title:	Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors.
Author:	Egloff, Ann Marie\|Grandis, Jennifer Rubin
PMID:	19636423

814.
Journal:	Rozhl Chir. 2009 Jun;88(6):303-7.
Title:	[Chemotherapy and biological treatment in the complex management of large intestinal and rectal carcinomas. When, why, how?].
Author:	Kubala, E\|Petruzelka, L\|Sedlackova, E
PMID:	19642320

815.
Journal:	Rev Med Liege. 2009 May-Jun;64(5-6):274-8.
Title:	[Monoclonal antibodies therapies for colorectal cancer: cetuximab, panitumumab and bevacizumab].
Author:	Piront, P\|Van Daele, D\|Belaiche, J\|Polus, M
PMID:	19642458

816.
Journal:	J Mol Diagn. 2009 Sep;11(5):381-9.
Title:	Pharmacogenetics of solid tumors: directed therapy in breast, lung, and colorectal cancer: a paper from the 2008 william beaumont hospital symposium on molecular pathology.
Author:	Snozek, Christine L H\|O'Kane, Dennis J\|Algeciras-Schimnich, Alicia
PMID:	19644023

817.
Journal:	Orv Hetil. 2009 Aug 23;150(34):1607-13.
Title:	[Tissue microarray (TMA) validated progression markers in colorectal cancer using antibody microarrays].
Author:	Spisak, Sandor\|Galamb, Barnabas\|Wichmann, Barnabas\|Sipos, Ferenc\|Galamb, Orsolya\|Solymosi, Norbert\|Nemes, Balazs\|Tulassay, Zsolt\|Molnar, Bela
PMID:	19648079

818.
Journal:	Anticancer Res. 2009 Aug;29(8):3369-74.
Title:	A novel K-ras mutation in colorectal cancer. A case report and literature review.
Author:	Palmirotta, Raffaele\|Savonarola, Annalisa\|Formica, Vincenzo\|Ludovici, Giorgia\|Del Monte, Girolamo\|Roselli, Mario\|Guadagni, Fiorella
PMID:	19661358

819.
Journal:	Curr Drug Targets. 2009 Oct;10(10):1033-40.
Title:	Anti-EGFR therapy in colorectal cancer: how to choose the right patient.
Author:	Meriggi, F\|Di Biasi, B\|Abeni, C\|Zaniboni, A
PMID:	19663767

820.
Journal:	Zhonghua Yi Xue Za Zhi. 2009 May 26;89(20):1387-90.
Title:	[Efficacy of cetuximab in therapy of metastatic colorectal cancer: a system evaluation].
Author:	Hou, Sheng-huai\|Liang, Xiao-bo\|Bai, Wen-qi\|Yang, Jun\|Yan, Dong\|Zhang, Xin\|Wang, Li-chun
PMID:	19671328

821.
Journal:	Mol Cancer Res. 2009 Aug;7(8):1244-52.
Title:	Oncogenic activating mutations are associated with local copy gain.
Author:	Modrek, Barmak\|Ge, Lin\|Pandita, Ajay\|Lin, Eva\|Mohan, Sankar\|Yue, Peng\|Guerrero, Steve\|Lin, William M\|Pham, Thinh\|Modrusan, Zora\|Seshagiri, Somasekar\|Stern, Howard M\|Waring, Paul\|Garraway, Levi A\|Chant, John\|Stokoe, David\|Cavet, Guy
PMID:	19671679

822.
Journal:	Development. 2009 Sep;136(18):3121-9.
Title:	Receptor tyrosine phosphatases control tracheal tube geometries through negative regulation of Egfr signaling.
Author:	Jeon, Mili\|Zinn, Kai
PMID:	19675131

823.
Journal:	Pathol Res Pract. 2009;205(12):858-62.
Title:	Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer.
Author:	Neumann, Jens\|Zeindl-Eberhart, Evelyn\|Kirchner, Thomas\|Jung, Andreas
PMID:	19679400

824.
Journal:	J Clin Invest. 2009 Sep;119(9):2702-13.
Title:	Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Author:	Lee, Daekee\|Yu, Ming\|Lee, Eunjung\|Kim, Hyunok\|Yang, Yanan\|Kim, Kyoungmi\|Pannicia, Christina\|Kurie, Jonathan M\|Threadgill, David W
PMID:	19690388

825.
Journal:	Gastroenterol Clin Biol. 2009 Aug-Sep;33(8-9):767-74.
Title:	[Pathology: on the way to molecular analysis].
Author:	Flejou, J-F\|Cervera, P
PMID:	19692190

826.
Journal:	Rev Med Suisse. 2009 Jul 15;5(211):1513-8.
Title:	[Predictive biomarkers in colorectal cancer].
Author:	Bosman, Fred T
PMID:	19694362

827.
Journal:	Gastroenterol Clin Biol. 2009 Aug-Sep;33(8-9):672-80.
Title:	[Targeted biotherapy: a revolution in the management of patients with colorectal cancer?].
Author:	Rougier, P\|Mitry, E
PMID:	19717258

828.
Journal:	J Clin Pharmacol. 2009 Oct;49(10):1142-56.
Title:	Population pharmacokinetic analysis of panitumumab in patients with advanced solid tumors.
Author:	Ma, Peiming\|Yang, Bing-Bing\|Wang, Yow-Ming\|Peterson, Mark\|Narayanan, Adimoolam\|Sutjandra, Liviawati\|Rodriguez, Rachelle\|Chow, Andrew
PMID:	19723673

829.
Journal:	Oncol Rep. 2009 Oct;22(4):709-17.
Title:	Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer.
Author:	Yasuda, Hiromi\|Tanaka, Koji\|Saigusa, Susumu\|Toiyama, Yuji\|Koike, Yuhki\|Okugawa, Yoshinaga\|Yokoe, Takeshi\|Kawamoto, Aya\|Inoue, Yasuhiro\|Miki, Chikao\|Kusunoki, Masato
PMID:	19724847

830.
Journal:	Ai Zheng. 2009 Sep;28(9):950-4.
Title:	[Expression and clinical significance of metastasis-related tumor markers in colorectal cancer].
Author:	Wan, Xiang-Bin\|Pan, Zhi-Zhong\|Ren, Ying-kun\|Ding, Pei-Rong\|Chen, Gong\|Wan, De-Sen
PMID:	19728913

831.
Journal:	Br J Pharmacol. 2009 Sep;158(2):610-20.
Title:	Modulation of cellular redox state underlies antagonism between oxaliplatin and cetuximab in human colorectal cancer cell lines.
Author:	Dahan, Laetitia\|Sadok, Amine\|Formento, Jean-Louis\|Seitz, Jean Francois\|Kovacic, Herve
PMID:	19732064

832.
Journal:	J Zhejiang Univ Sci B. 2009 Sep;10(9):668-74.
Title:	Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway.
Author:	Shan, Jian-zhen\|Xuan, Yan-yan\|Zheng, Shu\|Dong, Qi\|Zhang, Su-zhan
PMID:	19735099

833.
Journal:	J Clin Oncol. 2009 Oct 20;27(30):5068-74.
Title:	Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.
Author:	Jacobs, Bart\|De Roock, Wendy\|Piessevaux, Hubert\|Van Oirbeek, Robin\|Biesmans, Bart\|De Schutter, Jef\|Fieuws, Steffen\|Vandesompele, Jo\|Peeters, Marc\|Van Laethem, Jean-Luc\|Humblet, Yves\|Penault-Llorca, Frederique\|De Hertogh, Gert\|Laurent-Puig, Pierre\|Van Cuts
PMID:	19738126

834.
Journal:	J Natl Cancer Inst. 2009 Oct 7;101(19):1308-24.
Title:	Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer.
Author:	Siena, Salvatore\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Balfour, Julia\|Bardelli, Alberto
PMID:	19738166

835.
Journal:	Clin Colorectal Cancer. 2009 Apr;8(2):110-7.
Title:	Multiplexed cell signaling analysis of metastatic and nonmetastatic colorectal cancer reveals COX2-EGFR signaling activation as a potential prognostic pathway biomarker.
Author:	Pierobon, Mariaelena\|Calvert, Valerie\|Belluco, Claudio\|Garaci, Enrico\|Deng, Jianghong\|Lise, Mario\|Nitti, Donato\|Mammano, Enzo\|De Marchi, Francesco\|Liotta, Lance\|Petricoin, Emanuel
PMID:	19739273

836.
Journal:	Clin Colorectal Cancer. 2009 Apr;8(2):118-20.
Title:	Cetuximab-associated pulmonary toxicity.
Author:	Chua, Wei\|Peters, Matthew\|Loneragan, Robert\|Clarke, Stephen
PMID:	19739274

837.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2009 Sep;29(9):1870-3.
Title:	[Construction and identification of CerbB-2 siRNA expression plasmid and its transfer into human colon cancer cell lines HT-29].
Author:	Zhao, Dong-li\|Dang, Cheng-xue\|Sui, Yan-xia
PMID:	19778814

838.
Journal:	Cancer Res. 2009 Oct 1;69(19):7811-8.
Title:	An A13 repeat within the 3'-untranslated region of epidermal growth factor receptor (EGFR) is frequently mutated in microsatellite instability colon cancers and is associated with increased EGFR expression.
Author:	Yuan, Ziqiang\|Shin, Joongho\|Wilson, Andrew\|Goel, Sanjay\|Ling, Yi-He\|Ahmed, Naseem\|Dopeso, Higinio\|Jhawer, Minaxi\|Nasser, Shannon\|Montagna, Cristina\|Fordyce, Kenneth\|Augenlicht, Leonard H\|Aaltonen, Lauri A\|Arango, Diego\|Weber, Thomas K\|Mariadason, John M
PMID:	19789347

839.
Journal:	PLoS One. 2009 Oct 2;4(10):e7287.
Title:	Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer.
Author:	Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Nichelatti, Michele\|Molinari, Francesca\|De Dosso, Sara\|Saletti, Piercarlo\|Martini, Miriam\|Cipani, Tiziana\|Marrapese, Giovanna\|Mazzucchelli, Luca\|Lamba, Simona\|Veronese, Silvio\|Frattini, Milo\|Bardelli, Albe
PMID:	19806185

840.
Journal:	Pathobiology. 2009;76(5):267-73.
Title:	Antisense phosphorothioate oligodeoxynucleic acid for CD10 suppresses liver metastasis of colorectal cancer.
Author:	Luo, Yi\|Fujii, Kiyomu\|Ohmori, Hitoshi\|Sasahira, Tomonori\|Moriwaka, Yukiko\|Isobe, Mamoru\|Kuniyasu, Hiroki
PMID:	19816087

841.
Journal:	Anticancer Drugs. 2009 Nov;20(10):851-5.
Title:	Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities.
Author:	Modjtahedi, Helmout\|Essapen, Sharadah
PMID:	19826350

842.
Journal:	Am J Ther. 2009 Nov-Dec;16(6):477-9.
Title:	Personalized medicine enters the US marketplace: KRAS, anti-EGFR monoclonal antibodies, and colon cancer.
Author:	Lieberman, Ronald
PMID:	19829092

843.
Journal:	BMC Clin Pathol. 2009 Oct 15;9:8.
Title:	Experiences from treatment-predictive KRAS testing; high mutation frequency in rectal cancers from females and concurrent mutations in the same tumor.
Author:	Jonsson, Mats\|Ekstrand, Anna\|Edekling, Thomas\|Eberhard, Jakob\|Grabau, Dorthe\|Borg, David\|Nilbert, Mef
PMID:	19832985

844.
Journal:	Biochim Biophys Acta. 2009 Dec;1790(12):1651-9.
Title:	Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line.
Author:	Buzzi, Natalia\|Bilbao, Paola Scodelaro\|Boland, Ricardo\|de Boland, Ana Russo
PMID:	19836435

845.
Journal:	Nutr Cancer. 2009;61(4):544-53.
Title:	Curcumin synergizes with resveratrol to inhibit colon cancer.
Author:	Majumdar, Adhip P N\|Banerjee, Sanjeev\|Nautiyal, Jyoti\|Patel, Bhaumik B\|Patel, Vaishali\|Du, Jianhua\|Yu, Yingjie\|Elliott, Althea A\|Levi, Edi\|Sarkar, Fazlul H
PMID:	19838927

846.
Journal:	J Clin Oncol. 2009 Dec 10;27(35):5931-7.
Title:	KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial.
Author:	Richman, Susan D\|Seymour, Matthew T\|Chambers, Philip\|Elliott, Faye\|Daly, Catherine L\|Meade, Angela M\|Taylor, Graham\|Barrett, Jennifer H\|Quirke, Philip
PMID:	19884549

847.
Journal:	Clin Cancer Res. 2009 Nov 15;15(22):6780-9.
Title:	Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2.
Author:	Dougherty, Urszula\|Cerasi, Dario\|Taylor, Ieva\|Kocherginsky, Masha\|Tekin, Ummuhan\|Badal, Shamiram\|Aluri, Lata\|Sehdev, Amikar\|Cerda, Sonia\|Mustafi, Reba\|Delgado, Jorge\|Joseph, Loren\|Zhu, Hongyan\|Hart, John\|Threadgill, David\|Fichera, Alessandro\|Bissonnette,
PMID:	19903783

848.
Journal:	Clin Transl Oncol. 2009 Nov;11(11):737-47.
Title:	Biomarkers and anti-EGFR therapies for KRAS wild-type metastatic colorectal cancer.
Author:	Garcia-Saenz, Jose A\|Sastre, Javier\|Diaz-Rubio Garcia, Eduardo
PMID:	19917537

849.
Journal:	Am J Health Syst Pharm. 2009 Dec 1;66(23):2105-12.
Title:	Clinical and economic value of screening for Kras mutations as predictors of response to epidermal growth factor receptor inhibitors.
Author:	Mancl, Erin E\|Kolesar, Jill M\|Vermeulen, Lee C
PMID:	19923311

850.
Journal:	Clin Cancer Res. 2009 Dec 1;15(23):7322-9.
Title:	KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803.
Author:	Ogino, Shuji\|Meyerhardt, Jeffrey A\|Irahara, Natsumi\|Niedzwiecki, Donna\|Hollis, Donna\|Saltz, Leonard B\|Mayer, Robert J\|Schaefer, Paul\|Whittom, Renaud\|Hantel, Alexander\|Benson, Al B 3rd\|Goldberg, Richard M\|Bertagnolli, Monica M\|Fuchs, Charles S
PMID:	19934290

851.
Journal:	J Angiogenes Res. 2009 Sep 21;1:5.
Title:	DCE-MRI assessment of the effect of vandetanib on tumor vasculature in patients with advanced colorectal cancer and liver metastases: a randomized phase I study.
Author:	Mross, Klaus\|Fasol, Ulrike\|Frost, Annette\|Benkelmann, Robin\|Kuhlmann, Jan\|Buchert, Martin\|Unger, Clemens\|Blum, Hubert\|Hennig, Jurgen\|Milenkova, Tsveta P\|Tessier, Jean\|Krebs, Annetta D\|Ryan, Anderson J\|Fischer, Richard
PMID:	19946413

852.
Journal:	Transl Oncol. 2009 Dec;2(4):321-8.
Title:	Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX.
Author:	Yu, Yingjie\|Kanwar, Shailender S\|Patel, Bhaumik B\|Nautiyal, Jyoti\|Sarkar, Fazlul H\|Majumdar, Adhip Pn
PMID:	19956394

853.
Journal:	Clin Cancer Res. 2009 Dec 15;15(24):7492-7501.
Title:	Biomarkers of Resistance to Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer.
Author:	Banck, Michaela S\|Grothey, Axel
PMID:	20008849

854.
Journal:	Cancer Biol Ther. 2009 Oct;8(20):1914-21. Epub 2009 Oct 6.
Title:	The overexpression of ERCC-1 is involved in the resistance of lung cancer cells to cetuximab combined with DDP.
Author:	Li, Jing-Jing\|Ding, Ya\|Li, Dan-Dan\|Peng, Rui-Qing\|Feng, Gong-Kan\|Zeng, Yi-Xin\|Zhu, Xiao-Feng\|Zhang, Xiao-Shi
PMID:	20009541

855.
Journal:	J Oncol. 2009;2009:937305.
Title:	Vascular Endothelial Growth Factor plus Epidermal Growth Factor Receptor Dual Targeted Therapy in Metastatic Colorectal Cancer: Synergy or Antagonism?
Author:	Marshall, John L
PMID:	20016807

856.
Journal:	PLoS One. 2009 Dec 18;4(12):e8199.
Title:	KRAS mutations in primary colorectal cancer tumors and related metastases: a potential role in prediction of lung metastasis.
Author:	Cejas, Paloma\|Lopez-Gomez, Miriam\|Aguayo, Cristina\|Madero, Rosario\|de Castro Carpeno, Javier\|Belda-Iniesta, Cristobal\|Barriuso, Jorge\|Moreno Garcia, Victor\|Larrauri, Javier\|Lopez, Rocio\|Casado, Enrique\|Gonzalez-Baron, Manuel\|Feliu, Jaime
PMID:	20020061

857.
Journal:	Bull Cancer. 2009 Dec;96 Suppl:S15-22.
Title:	[Technical considerations for KRAS testing in colorectal cancer. The pathologist's point of view].
Author:	Bibeau, F\|Frugier, H\|Denouel, A\|Sabourin, J-C\|Boissiere-Michot, F
PMID:	20034866

858.
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PMID:	20034867

859.
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860.
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861.
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PMID:	20034870

862.
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Title:	Autophagy: novel action of panitumumab in colon cancer.
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PMID:	20044619

863.
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864.
Journal:	Curr Opin Mol Ther. 2009 Dec;11(6):611-22.
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PMID:	20072938

865.
Journal:	Oncology. 2009;77(6):400-10.
Title:	EGFR signaling and drug discovery.
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PMID:	20130423

866.
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Title:	The long and winding road to useful predictive factors for anti-EGFR therapy in metastatic colorectal carcinoma: the KRAS/BRAF pathway.
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PMID:	20130433

867.
Journal:	Oncology. 2009;77 Suppl 1:69-74.
Title:	The dark side of the moon: the PI3K/PTEN/AKT pathway in colorectal carcinoma.
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PMID:	20130434

868.
Journal:	Tumori. 2009 Nov-Dec;95(6):753-61.
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869.
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870.
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871.
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PMID:	20616891

872.
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PMID:	20616896

873.
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874.
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PMID:	20698358

875.
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PMID:	21188126

876.
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877.
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878.
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879.
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880.
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881.
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PMID:	19616446

882.
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Title:	Improving disease control in advanced colorectal cancer: Panitumumab and cetuximab.
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883.
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PMID:	19701635

884.
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885.
Journal:	Gastroenterology. 2010 Feb;138(2):435-46.
Title:	In vivo molecular imaging of colorectal cancer with confocal endomicroscopy by targeting epidermal growth factor receptor.
Author:	Goetz, Martin\|Ziebart, Alex\|Foersch, Sebastian\|Vieth, Michael\|Waldner, Maximilian J\|Delaney, Peter\|Galle, Peter R\|Neurath, Markus F\|Kiesslich, Ralf
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886.
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PMID:	19862647

887.
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888.
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889.
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890.
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Title:	Investigation of papulopustular eruptions caused by cetuximab treatment shows altered differentiation markers and increases in inflammatory cytokines.
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PMID:	19903175

891.
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892.
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893.
Journal:	Ann Surg Oncol. 2010 Feb;17(2):624-33.
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894.
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895.
Journal:	Recent Pat Anticancer Drug Discov. 2010 Jun;5(2):142-51.
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896.
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897.
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898.
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899.
Journal:	Cancer Control. 2010 Jan;17(1):7-15.
Title:	Current progress in targeted therapy for colorectal cancer.
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900.
Journal:	Lancet Oncol. 2010 Feb;11(2):121-8.
Title:	Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial.
Author:	Mitsudomi, Tetsuya\|Morita, Satoshi\|Yatabe, Yasushi\|Negoro, Shunichi\|Okamoto, Isamu\|Tsurutani, Junji\|Seto, Takashi\|Satouchi, Miyako\|Tada, Hirohito\|Hirashima, Tomonori\|Asami, Kazuhiro\|Katakami, Nobuyuki\|Takada, Minoru\|Yoshioka, Hiroshige\|Shibata, Kazuhiko\|K
PMID:	20022809

901.
Journal:	Ann Surg Oncol. 2010 May;17(5):1429-34.
Title:	KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications.
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902.
Journal:	Int J Cancer. 2010 Sep 1;127(6):1321-31.
Title:	Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer.
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PMID:	20049837

903.
Journal:	J Clin Rheumatol. 2010 Jan;16(1):32-3.
Title:	Cetuximab in the treatment of rheumatoid arthritis.
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904.
Journal:	Cancer Lett. 2010 Jul 1;293(1):23-30.
Title:	Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.
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905.
Journal:	Exp Cell Res. 2010 Apr 15;316(7):1083-100.
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Author:	Kruser, Tim J\|Wheeler, Deric L
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906.
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907.
Journal:	Bull Cancer. 2010 Feb;97(2):265-80.
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908.
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PMID:	20085858

909.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):358-65.
Title:	Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients.
Author:	Chung, Christine H\|Seeley, Erin H\|Roder, Heinrich\|Grigorieva, Julia\|Tsypin, Maxim\|Roder, Joanna\|Burtness, Barbara A\|Argiris, Athanassios\|Forastiere, Arlene A\|Gilbert, Jill\|Murphy, Barbara\|Caprioli, Richard M\|Carbone, David P\|Cohen, Ezra E W
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910.
Journal:	Curr Cancer Drug Targets. 2010 Feb;10(1):68-79.
Title:	Molecular predictors of efficacy to anti-EGFR agents in colorectal cancer patients.
Author:	Ruzzo, Annamaria\|Graziano, Francesco\|Canestrari, Emanuele\|Magnani, Mauro
PMID:	20088793

911.
Journal:	Expert Opin Investig Drugs. 2010 Mar;19(3):357-69.
Title:	Colorectal cancer in review: the role of the EGFR pathway.
Author:	Saif, Muhammad W
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912.
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Title:	Insulin-like growth factor 1 expression correlates with clinical outcome in K-RAS wild type colorectal cancer patients treated with cetuximab and irinotecan.
Author:	Scartozzi, Mario\|Mandolesi, Alessandra\|Giampieri, Riccardo\|Pierantoni, Chiara\|Loupakis, Fotios\|Zaniboni, Alberto\|Galizia, Eva\|Giustini, Lucio\|Silva, Rosa Rita\|Bisonni, Renato\|Berardi, Rossana\|Biagetti, Simona\|Menzo, Stefano\|Falcone, Alfredo\|Bearzi, Italo\|
PMID:	20099280

913.
Journal:	J Clin Oncol. 2010 Feb 20;28(6):918-27.
Title:	Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small-cell lung cancer.
Author:	Khambata-Ford, Shirin\|Harbison, Christopher T\|Hart, Lowell L\|Awad, Melissa\|Xu, Li-An\|Horak, Christine E\|Dakhil, Shaker\|Hermann, Robert C\|Lynch, Thomas J\|Weber, Martin R
PMID:	20100958

914.
Journal:	J Clin Oncol. 2010 Mar 1;28(7):1254-61.
Title:	Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer.
Author:	Bardelli, Alberto\|Siena, Salvatore
PMID:	20100961

915.
Journal:	Clin Cancer Res. 2010 Feb 1;16(3):790-9.
Title:	Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases.
Author:	Baldus, Stephan E\|Schaefer, Karl-L\|Engers, Rainer\|Hartleb, Dinah\|Stoecklein, Nikolas H\|Gabbert, Helmut E
PMID:	20103678

916.
Journal:	Clin Oncol (R Coll Radiol). 2010 May;22(4):272-80.
Title:	Gene expression profiles of epidermal growth factor receptor, vascular endothelial growth factor and hypoxia-inducible factor-1 with special reference to local responsiveness to neoadjuvant chemoradiotherapy and disease recurrence after rectal cancer surg
Author:	Toiyama, Y\|Inoue, Y\|Saigusa, S\|Okugawa, Y\|Yokoe, T\|Tanaka, K\|Miki, C\|Kusunoki, M
PMID:	20117921

917.
Journal:	Clin J Oncol Nurs. 2010 Feb;14(1):92-100.
Title:	Incorporating new data on colorectal cancer into nursing practice.
Author:	Viale, Pamela Hallquist
PMID:	20118032

918.
Journal:	Oncologist. 2010;15(2):157-67.
Title:	Predicting response to EGFR inhibitors in metastatic colorectal cancer: current practice and future directions.
Author:	Shankaran, Veena\|Obel, Jennifer\|Benson, Al B 3rd
PMID:	20133499

919.
Journal:	Br J Cancer. 2010 Feb 16;102(4):693-703.
Title:	Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine.
Author:	Smith, G\|Bounds, R\|Wolf, H\|Steele, R J C\|Carey, F A\|Wolf, C R
PMID:	20147967

920.
Journal:	Mol Aspects Med. 2010 Apr;31(2):171-8.
Title:	The molecular therapy of colorectal cancer.
Author:	Waldner, Maximilian J\|Neurath, Markus F
PMID:	20171980

921.
Journal:	Acta Oncol. 2010 Apr;49(3):278-86.
Title:	Cetuximab and chemoradiation for rectal cancer--is the water getting muddy?
Author:	Glynne-Jones, Rob\|Mawdsley, Suzy\|Harrison, Mark
PMID:	20180626

922.
Journal:	Histol Histopathol. 2010 Apr;25(4):473-84.
Title:	REG IV overexpression in an early stage of colorectal carcinogenesis: an immunohistochemical study.
Author:	Li, Xiao-Han\|Zheng, Yang\|Zheng, Hua-Chuan\|Takahashi, Hiroyuki\|Yang, Xiang-Hong\|Masuda, Shinji\|Takano, Yasuo
PMID:	20183800

923.
Journal:	BMC Med Genet. 2010 Feb 26;11:34.
Title:	Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer.
Author:	Yunxia, Zuo\|Jun, Cao\|Guanshan, Zhu\|Yachao, Lu\|Xueke, Zhou\|Jin, Li
PMID:	20184776

924.
Journal:	Int J Oncol. 2010 Apr;36(4):941-53.
Title:	Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway.
Author:	Lee, Hwa Young\|Crawley, Suzanne\|Hokari, Ryota\|Kwon, Sungwon\|Kim, Young S
PMID:	20198339

925.
Journal:	World J Gastroenterol. 2010 Mar 14;16(10):1177-87.
Title:	Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer.
Author:	Saridaki, Zacharenia\|Georgoulias, Vassilis\|Souglakos, John
PMID:	20222160

926.
Journal:	Rinsho Byori. 2010 Feb;58(2):169-74.
Title:	[Current update and testing procedures for genetic diagnosis in malignant neoplasm: additional information on pathological tests].
Author:	Funato, Tadao\|Takeda, Mayu
PMID:	20229816

927.
Journal:	Br J Cancer. 2010 Mar 30;102(7):1137-44.
Title:	Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients.
Author:	Montagut, C\|Iglesias, M\|Arumi, M\|Bellosillo, B\|Gallen, M\|Martinez-Fernandez, A\|Martinez-Aviles, L\|Canadas, I\|Dalmases, A\|Moragon, E\|Lema, L\|Serrano, S\|Rovira, A\|Rojo, F\|Bellmunt, J\|Albanell, J
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928.
Journal:	Anticancer Res. 2010 Feb;30(2):319-25.
Title:	Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
Author:	Patel, Bhaumik B\|Gupta, Deepshika\|Elliott, Althea A\|Sengupta, Vivek\|Yu, Yingjie\|Majumdar, Adhip P N
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Journal:	Nat Rev Clin Oncol. 2010 May;7(5):251-65.
Title:	The molecular pathology of cancer.
Author:	Harris, Timothy J R\|McCormick, Frank
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930.
Journal:	Cancer Chemother Pharmacol. 2010 Aug;66(3):605-9.
Title:	Acquired KRAS mutations during progression of colorectal cancer metastases: possible implications for therapy and prognosis.
Author:	Bouchahda, Mohamed\|Karaboue, Abdoulaye\|Saffroy, Raphael\|Innominato, Pasquale\|Gorden, Lee\|Guettier, Catherine\|Adam, Rene\|Levi, Francis
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931.
Journal:	Cancer Treat Rev. 2010 Nov;36(7):550-6.
Title:	Molecular predictive and prognostic markers in colon cancer.
Author:	Winder, Thomas\|Lenz, Heinz-Josef
PMID:	20363564

932.
Journal:	Expert Opin Ther Targets. 2010 Jun;14(6):593-601.
Title:	Targeting NF-kappaB for colorectal cancer.
Author:	Sakamoto, Kei\|Maeda, Shin
PMID:	20367537

933.
Journal:	Int J Oncol. 2010 May;36(5):1137-44.
Title:	KRAS mutations in Slovene patients with colorectal cancer: frequency, distribution and correlation with the response to treatment.
Author:	Licar, Alenka\|Cerkovnik, Petra\|Ocvirk, Janja\|Novakovic, Srdjan
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934.
Journal:	Cancer Lett. 2010 Sep 1;295(1):7-16.
Title:	Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: an update on the molecular mechanisms.
Author:	Wu, William Ka Kei\|Sung, Joseph Jao Yiu\|Lee, Chung Wa\|Yu, Jun\|Cho, Chi Hin
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935.
Journal:	Oncogene. 2010 May 27;29(21):3033-43.
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936.
Journal:	BMC Cancer. 2010 Apr 13;10:136.
Title:	Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer.
Author:	Sanchez-Munoz, Alfonso\|Gallego, Elena\|de Luque, Vanessa\|Perez-Rivas, Luis G\|Vicioso, Luis\|Ribelles, Nuria\|Lozano, Jose\|Alba, Emilio
PMID:	20385028

937.
Journal:	Bull Cancer. 2010 Apr;97(4):469-74.
Title:	[Treatment of advanced and/or metastatic colorectal cancer with bevacizumab in combination with oxaliplatin-based chemotherapy (Folfox7 regimen)].
Author:	Oukkal, M\|Djilat, K\|Hadjam, R M\|Mahgoun, Mt\|Bentabak, K\|Graba, A\|Smail, N\|Kaci, N Ait\|Ahmed, R Baba\|Bouzid, K
PMID:	20385517

938.
Journal:	Clin Trials. 2010 Oct;7(5):567-73.
Title:	Predictive biomarker validation in practice: lessons from real trials.
Author:	Mandrekar, Sumithra J\|Sargent, Daniel J
PMID:	20392785

939.
Journal:	Expert Rev Anticancer Ther. 2010 Apr;10(4):499-505.
Title:	Panitumumab: a new frontier of target therapy for the treatment of metastatic colorectal cancer.
Author:	Addeo, Raffaele\|Caraglia, Michele\|Cerbone, Domenico\|Frega, Nicola\|Cimmino, Gaetano\|Abbruzzese, Alberto\|Del Prete, Salvatore
PMID:	20397915

940.
Journal:	J Transl Med. 2010 Apr 16;8:36.
Title:	Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab.
Author:	Campanella, Carla\|Mottolese, Marcella\|Cianciulli, Anna\|Torsello, Angela\|Merola, Roberta\|Sperduti, Isabella\|Melucci, Elisa\|Conti, Salvatore\|Diodoro, Maria Grazia\|Zeuli, Massimo\|Paoletti, Giancarlo\|Cognetti, Francesco\|Garufi, Carlo
PMID:	20398370

941.
Journal:	Eur J Cancer. 2010 Jun;46(9):1703-11.
Title:	Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC).
Author:	Correale, Pierpaolo\|Marra, Monica\|Remondo, Cinzia\|Migali, Cristina\|Misso, Gabriella\|Arcuri, Felice Paolo\|Del Vecchio, Maria Teresa\|Carducci, Antonietta\|Loiacono, Lucia\|Tassone, Pierfrancesco\|Abbruzzese, Alberto\|Tagliaferri, Pierosandro\|Caraglia, Michele
PMID:	20399639

942.
Journal:	Clin Ther. 2010 Mar;32(3):437-53.
Title:	Monoclonal antibodies in the treatment of metastatic colorectal cancer: a review.
Author:	Tol, Jolien\|Punt, Cornelis J A
PMID:	20399983

943.
Journal:	Curr Clin Pharmacol. 2010 Aug;5(3):166-77.
Title:	Molecular targeted therapy in prevalent tumors: learning from the past and future perspectives.
Author:	Metzger-Filho, Otto\|Moulin, Camilo\|Awada, Ahmad
PMID:	20406173

944.
Journal:	J Cell Sci. 2010 May 15;123(Pt 10):1716-23.
Title:	MUC1 regulates nuclear localization and function of the epidermal growth factor receptor.
Author:	Bitler, Benjamin G\|Goverdhan, Aarthi\|Schroeder, Joyce A
PMID:	20406885

945.
Journal:	Eur J Cancer. 2010 Jul;46(11):1997-2009.
Title:	Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.
Author:	Tol, Jolien\|Dijkstra, Jeroen R\|Klomp, Marjolein\|Teerenstra, Steven\|Dommerholt, Martin\|Vink-Borger, M Elisa\|van Cleef, Patricia H\|van Krieken, J Han\|Punt, Cornelis J A\|Nagtegaal, Iris D
PMID:	20413299

946.
Journal:	Gastroenterology. 2010 Jun;138(6):2163-76.
Title:	Vascular endothelial growth factor and epidermal growth factor signaling pathways as therapeutic targets for colorectal cancer.
Author:	Winder, Thomas\|Lenz, Heinz-Josef
PMID:	20420953

947.
Journal:	Discov Med. 2010 Apr;9(47):328-36.
Title:	Current issues in the targeted therapy of advanced colorectal cancer.
Author:	Knijn, Nikki\|Tol, Jolien\|Punt, Cornelis J A
PMID:	20423677

948.
Journal:	Curr Oncol Rep. 2010 May;12(3):160-7.
Title:	KRAS testing and its importance in colorectal cancer.
Author:	Patil, Deepa T\|Fraser, Cory R\|Plesec, Thomas P
PMID:	20425075

949.
Journal:	Recent Pat DNA Gene Seq. 2010 Jun;4(2):86-93.
Title:	Recent patents and advances in genomic biomarker discovery for colorectal cancers.
Author:	Quyun, Chen\|Ye, Zhiyun\|Lin, Sheng-Cai\|Lin, Biaoyang
PMID:	20426761

950.
Journal:	Clin Cancer Res. 2010 May 15;16(10):2709-14.
Title:	Integration of epidermal growth factor receptor inhibitors with preoperative chemoradiation.
Author:	Debucquoy, Annelies\|Machiels, Jean-Pascal\|McBride, William H\|Haustermans, Karin
PMID:	20427690

951.
Journal:	Oncogene. 2010 Jun 24;29(25):3677-90.
Title:	p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation.
Author:	Damiano, L\|Di Stefano, P\|Camacho Leal, M P\|Barba, M\|Mainiero, F\|Cabodi, S\|Tordella, L\|Sapino, A\|Castellano, I\|Canel, M\|Frame, M\|Turco, E\|Defilippi, P
PMID:	20453886

952.
Journal:	BMC Cancer. 2010 May 11;10:189.
Title:	Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas.
Author:	Van Damme, Nancy\|Deron, Philippe\|Van Roy, Nadine\|Demetter, Pieter\|Bols, Alain\|Van Dorpe, Jo\|Baert, Filip\|Van Laethem, Jean-Luc\|Speleman, Franki\|Pauwels, Patrick\|Peeters, Marc
PMID:	20459770

953.
Journal:	Cytokine Growth Factor Rev. 2010 Apr-Jun;21(2-3):85-9.
Title:	Navigating the clinical development landscape for oncolytic viruses and other cancer therapeutics: no shortcuts on the road to approval.
Author:	Breitbach, Caroline J\|Reid, Tony\|Burke, James\|Bell, John C\|Kirn, David H
PMID:	20472490

954.
Journal:	Gan To Kagaku Ryoho. 2010 May;37(5):787-90.
Title:	[Anti-epidermal growth factor receptor monoclonal antibodies induced adverse events].
Author:	Tsuji, Yasushi\|Kogawa, Takahiro\|Abe, Masakazu
PMID:	20495307

955.
Journal:	Gan To Kagaku Ryoho. 2010 May;37(5):799-804.
Title:	[The anti EGFR antibody indication between the Japanese and overseas guidelines].
Author:	Nozaki, Akira\|Shinozaki, Eiji\|Mizunuma, Nobuyuki
PMID:	20495310

956.
Journal:	Pol J Pathol. 2010;61(1):23-6.
Title:	BRAF mutations in sporadic colorectal carcinoma from polish patients.
Author:	Wojcik, Piotr\|Okon, Krzysztof\|Osuch, Czeslaw\|Klimkowska, Agnieszka\|Tomaszewska, Romana
PMID:	20496269

957.
Journal:	Pharmacogenomics. 2010 Jun;11(6):747-61.
Title:	Pharmacogenetic analysis in neoadjuvant chemoradiation for rectal cancer: high incidence of somatic mutations and their relation with response.
Author:	Balboa, Emilia\|Duran, Goretti\|Lamas, Maria Jesus\|Gomez-Caamano, Antonio\|Celeiro-Munoz, Catuxa\|Lopez, Rafael\|Carracedo, Angel\|Barros, Francisco
PMID:	20504250

958.
Journal:	Arch Pathol Lab Med. 2010 Jun;134(6):853-63.
Title:	Practical and molecular evaluation of colorectal cancer: new roles for the pathologist in the era of targeted therapy.
Author:	De Hertogh, Gert\|Geboes, Karen Paula
PMID:	20524863

959.
Journal:	Carcinogenesis. 2010 Sep;31(9):1523-30.
Title:	Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association.
Author:	Rogers, Kristina R\|Kikawa, Keith D\|Mouradian, Michael\|Hernandez, Karla\|McKinnon, Kristen M\|Ahwah, Shayne M\|Pardini, Ronald S
PMID:	20525880

960.
Journal:	Nat Rev Drug Discov. 2010 Jul;9(7):523-35.
Title:	Integrating molecular diagnostics into anticancer drug discovery.
Author:	Petak, Istvan\|Schwab, Richard\|Orfi, Laszlo\|Kopper, Laszlo\|Keri, Gyorgy
PMID:	20531274

961.
Journal:	PLoS One. 2010 Jun 4;5(6):e10966.
Title:	Hypoxia activates the K-ras proto-oncogene to stimulate angiogenesis and inhibit apoptosis in colon cancer cells.
Author:	Zeng, Min\|Kikuchi, Hirotoshi\|Pino, Maria S\|Chung, Daniel C
PMID:	20532039

962.
Journal:	Nihon Rinsho. 2010 Jun;68(6):1085-93.
Title:	[Antibody therapy in cancer].
Author:	Komatsu, Hirokazu
PMID:	20535960

963.
Journal:	Nihon Rinsho. 2010 Jun;68(6):1143-9.
Title:	[Transition of chemotherapy for metastatic colorectal cancer and recent advances].
Author:	Muro, Kei
PMID:	20535969

964.
Journal:	J Med Chem. 2010 Jul 8;53(13):4980-8.
Title:	Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor lead identification.
Author:	Coumar, Mohane Selvaraj\|Chu, Chang-Ying\|Lin, Cheng-Wei\|Shiao, Hui-Yi\|Ho, Yun-Lung\|Reddy, Randheer\|Lin, Wen-Hsing\|Chen, Chun-Hwa\|Peng, Yi-Hui\|Leou, Jiun-Shyang\|Lien, Tzu-Wen\|Huang, Chin-Ting\|Fang, Ming-Yu\|Wu, Szu-Huei\|Wu, Jian-Sung\|Chittimalla, Santhosh Ku
PMID:	20550212

965.
Journal:	Cancer Sci. 2010 Sep;101(9):2048-53.
Title:	Immunoglobulin G fragment C receptor polymorphisms and KRAS mutations: are they useful biomarkers of clinical outcome in advanced colorectal cancer treated with anti-EGFR-based therapy?
Author:	Paez, David\|Pare, Laia\|Espinosa, Inigo\|Salazar, Juliana\|del Rio, Elisabeth\|Barnadas, Agusti\|Marcuello, Eugenio\|Baiget, Montserrat
PMID:	20550522

966.
Journal:	Gut. 2010 Jun;59(6):838-58.
Title:	Targeted treatments in colorectal cancer: state of the art and future perspectives.
Author:	Arnold, Dirk\|Seufferlein, Thomas
PMID:	20551469

967.
Journal:	Nat Rev Clin Oncol. 2010 Sep;7(9):493-507.
Title:	Understanding resistance to EGFR inhibitors-impact on future treatment strategies.
Author:	Wheeler, Deric L\|Dunn, Emily F\|Harari, Paul M
PMID:	20551942

968.
Journal:	Clin Cancer Res. 2010 Aug 1;16(15):3811-8.
Title:	New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways.
Author:	Dasari, Arvind\|Messersmith, Wells A
PMID:	20554751

969.
Journal:	Neoplasia. 2010 Jun;12(6):443-52.
Title:	Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation.
Author:	van Houdt, Winan J\|Hoogwater, Frederik J H\|de Bruijn, Menno T\|Emmink, Benjamin L\|Nijkamp, Maarten W\|Raats, Danielle A E\|van der Groep, Petra\|van Diest, Paul\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	20563247

970.
Journal:	Cancer. 2010 Aug 1;116(15):3537-48.
Title:	The role of targeted agents in preoperative chemoradiation for rectal cancer.
Author:	Wadlow, Raymond C\|Ryan, David P
PMID:	20564106

971.
Journal:	BMC Med Genomics. 2010 Jun 22;3:23.
Title:	An algorithm for classifying tumors based on genomic aberrations and selecting representative tumor models.
Author:	Lu, Xin\|Zhang, Ke\|Van Sant, Charles\|Coon, John\|Semizarov, Dimitri
PMID:	20569491

972.
Journal:	Cancer Res. 2010 Jul 15;70(14):5901-11.
Title:	Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Author:	Janakiraman, Manickam\|Vakiani, Efsevia\|Zeng, Zhaoshi\|Pratilas, Christine A\|Taylor, Barry S\|Chitale, Dhananjay\|Halilovic, Ensar\|Wilson, Manda\|Huberman, Kety\|Ricarte Filho, Julio Cezar\|Persaud, Yogindra\|Levine, Douglas A\|Fagin, James A\|Jhanwar, Suresh C\|Mar
PMID:	20570890

973.
Journal:	Chirurg. 2010 Jun;81(6):507-15.
Title:	[Current medicinal treatment of metastasized colorectal carcinoma].
Author:	Folprecht, G
PMID:	20574792

974.
Journal:	Oncologist. 2010;15(7):699-731.
Title:	A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.
Author:	Deschoolmeester, Vanessa\|Baay, Marc\|Specenier, Pol\|Lardon, Filip\|Vermorken, Jan B
PMID:	20584808

975.
Journal:	Digestion. 2010;82(3):145-9.
Title:	Intranuclear translocation signaling of HB-EGF carboxy-terminal fragment and mucosal defense through cell proliferation and migration in digestive tracts.
Author:	Tanida, Satoshi\|Kataoka, Hiromi\|Mizoshita, Tsutomu\|Shimura, Takaya\|Kamiya, Takeshi\|Joh, Takashi
PMID:	20588025

976.
Journal:	Drug Discov Today. 2010 Jul;15(13-14):502-16.
Title:	Therapeutic modulation of k-ras signaling in colorectal cancer.
Author:	Krens, Lisanne L\|Baas, Jara M\|Gelderblom, Hans\|Guchelaar, Henk-Jan
PMID:	20594936

977.
Journal:	Cancer Biol Ther. 2010 Sep 1;10(5):416-21. Epub 2010 Sep 8.
Title:	EGFR expression variance in paired colorectal cancer primary and metastatic tumors.
Author:	Yarom, Nirit\|Marginean, Celia\|Moyana, Terence\|Gorn-Hondermann, Ivan\|Birnboim, H Chaim\|Marginean, Horia\|Auer, Rebecca C\|Vickers, Michael\|Asmis, Timothy R\|Maroun, Jean\|Jonker, Derek
PMID:	20595818

978.
Journal:	Int J Oncol. 2010 Aug;37(2):473-82.
Title:	Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells.
Author:	Li, Zhuzhu\|Yao, Hangping\|Guin, Sunny\|Padhye, Snehal S\|Zhou, Yong-Qing\|Wang, Ming-Hai
PMID:	20596675

979.
Journal:	Gastroenterol Clin Biol. 2010 Oct;34(10):516-22.
Title:	Ursodeoxycholic acid and chemoprevention of colorectal cancer.
Author:	Serfaty, L\|Bissonnette, M\|Poupon, R
PMID:	20609543

980.
Journal:	Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12605-10.
Title:	T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells.
Author:	Lutterbuese, Ralf\|Raum, Tobias\|Kischel, Roman\|Hoffmann, Patrick\|Mangold, Susanne\|Rattel, Benno\|Friedrich, Matthias\|Thomas, Oliver\|Lorenczewski, Grit\|Rau, Doris\|Schaller, Evelyne\|Herrmann, Ines\|Wolf, Andreas\|Urbig, Thomas\|Baeuerle, Patrick A\|Kufer, Peter
PMID:	20616015

981.
Journal:	Cancer Sci. 2010 Sep;101(9):2033-8.
Title:	Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells.
Author:	Feng, Yin-Hsun\|Tsao, Chao-Jung\|Wu, Chao-Liang\|Chang, Jan-Gowth\|Lu, Pei-Jung\|Yeh, Kun-Tu\|Shieh, Gia-Shing\|Shiau, Ai-Li\|Lee, Jeng-Chang
PMID:	20624167

982.
Journal:	Clin Colorectal Cancer. 2010 Jun;9 Suppl 1:S44-50.
Title:	Treatment paradigms with epidermal growth factor receptor-targeted therapies in colorectal cancer.
Author:	Stein, Stacey\|Cohen, Deirdre J\|Hochster, Howard S
PMID:	20630850

983.
Journal:	Ann Pharm Fr. 2010 Jul;68(4):233-53.
Title:	[Recent developments of pharmacogenomics in the treatment of colorectal cancers].
Author:	Astier, A
PMID:	20637356

984.
Journal:	Anat Rec (Hoboken). 2010 Sep;293(9):1506-11.
Title:	Gene mutations in epidermal growth factor receptor signaling network and their association with survival in Chinese patients with metastatic colorectal cancers.
Author:	Liao, Wangjun\|Liao, Yulin\|Zhou, Jeff X\|Xie, Jianming\|Chen, Jinzhang\|Huang, Weizhen\|Luo, Rongcheng
PMID:	20652941

985.
Journal:	Recent Results Cancer Res. 2010;182:155-66.
Title:	Multimodality therapy for adenocarcinoma of the esophagus, gastric cardia, and upper gastric third.
Author:	Reynolds, John V\|Murphy, Thomas J\|Ravi, Narayamasamy
PMID:	20676879

986.
Journal:	Curr Oncol. 2010 Jul;17 Suppl 1:S18-30.
Title:	Adverse events associated with anti-EGFR therapies for the treatment of metastatic colorectal cancer.
Author:	Fakih, M\|Vincent, M
PMID:	20680104

987.
Journal:	Curr Oncol. 2010 Jul;17 Suppl 1:S31-40.
Title:	KRAS mutation testing in the treatment of metastatic colorectal cancer with anti-EGFR therapies.
Author:	Soulieres, D\|Greer, W\|Magliocco, Anthony M\|Huntsman, D\|Young, S\|Tsao, M-S\|Kamel-Reid, S
PMID:	20680106

988.
Journal:	J Clin Oncol. 2010 Sep 20;28(27):4240-6.
Title:	Randomized, phase II study of the insulin-like growth factor-1 receptor inhibitor IMC-A12, with or without cetuximab, in patients with cetuximab- or panitumumab-refractory metastatic colorectal cancer.
Author:	Reidy, Diane Lauren\|Vakiani, Efsevia\|Fakih, Marwan G\|Saif, Muhammad Wasif\|Hecht, Joel Randolph\|Goodman-Davis, Noah\|Hollywood, Ellen\|Shia, Jinru\|Schwartz, Jonathan\|Chandrawansa, Kumari\|Dontabhaktuni, Aruna\|Youssoufian, Hagop\|Solit, David B\|Saltz, Leonard B
PMID:	20713879

989.
Journal:	Histopathology. 2010 Aug;57(2):233-43.
Title:	Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer.
Author:	Karamitopoulou, Eva\|Lugli, Alessandro\|Panayiotides, Ioannis\|Karakitsos, Petros\|Peros, George\|Rallis, George\|Patsouris, Efstratios S\|Terracciano, Luigi\|Zlobec, Inti
PMID:	20716165

990.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):824-33.
Title:	Strategies for overcoming inherent and acquired resistance to EGFR inhibitors by targeting downstream effectors in the RAS/PI3K pathway.
Author:	Weickhardt, Andrew J\|Tebbutt, Niall C\|Mariadason, John M
PMID:	20718704

991.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):813-23.
Title:	KRAS mutation testing of colorectal cancer for anti-EGFR therapy: dogmas versus evidence.
Author:	Timar, Jozsef\|Hegedus, Balazs\|Raso, Erzsebet
PMID:	20718705

992.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):799-812.
Title:	Predictive molecular markers of response to epidermal growth factor receptor(EGFR) family-targeted therapies.
Author:	Barton, Sarah\|Starling, Naureen\|Swanton, Charles
PMID:	20718710

993.
Journal:	Autophagy. 2010 Oct;6(7):863-70.
Title:	UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy.
Author:	Knaevelsrud, Helene\|Ahlquist, Terje\|Merok, Marianne A\|Nesbakken, Arild\|Stenmark, Harald\|Lothe, Ragnhild A\|Simonsen, Anne
PMID:	20724836

994.
Journal:	Arch Pharm (Weinheim). 2010 Sep;343(9):489-99.
Title:	Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials.
Author:	Shehzad, Adeeb\|Wahid, Fazli\|Lee, Young Sup
PMID:	20726007

995.
Journal:	Mol Cell Probes. 2010 Dec;24(6):376-80.
Title:	High sensitive mutation analysis on KRAS gene using LNA/DNA chimeras as PCR amplification blockers of wild-type alleles.
Author:	Huang, Qing\|Wang, Gui-Yu\|Huang, Jun-Fu\|Zhang, Bo\|Fu, Wei-Ling
PMID:	20732413

996.
Journal:	Clin Adv Hematol Oncol. 2010 Jun;8(6):437-44.
Title:	BRAF testing in advanced colorectal cancer: is it ready for prime time?
Author:	Phillips, Brooke\|Kalady, Matthew\|Kim, Richard
PMID:	20733556

997.
Journal:	Oncology. 2010;78(5-6):369-75.
Title:	Predictive factors of complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer.
Author:	Carlomagno, Chiara\|Pepe, Stefano\|D'Armiento, Francesco Paolo\|D'Armiento, Maria\|Cannella, Lucia\|De Stefano, Alfonso\|Crispo, Anna\|Giordano, Marcella\|De Placido, Sabino
PMID:	20798559

998.
Journal:	Clin Cancer Res. 2010 Oct 15;16(20):4990-5001.
Title:	Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells.
Author:	Martinelli, Erika\|Troiani, Teresa\|Morgillo, Floriana\|Rodolico, Gabriella\|Vitagliano, Donata\|Morelli, Maria Pia\|Tuccillo, Concetta\|Vecchione, Loredana\|Capasso, Anna\|Orditura, Michele\|De Vita, Ferdinando\|Eckhardt, S Gail\|Santoro, Massimo\|Berrino, Liberato\|C
PMID:	20810384

999.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2010 Aug;30(8):1817-9, 1823.
Title:	[Effect of anti-EGFR monoclonal antibody on chemosensitivity of human colon cancer cells and the mechanism].
Author:	Cao, Meng-ran\|Li, Xiao-yan\|Zheng, Da-yong\|Yang, Lin\|Lv, Cheng-wei\|Luo, Rong-cheng
PMID:	20813673

1000.
Journal:	Pathologe. 2010 Oct;31 Suppl 2:280-4.
Title:	[mRNA quantification. The next challenge in routine diagnostics].
Author:	Jung, A\|Jaitner, S\|Schaffauer, A J\|Kirchner, T
PMID:	20824431

1001.
Journal:	Cancer Lett. 2010 Dec 18;299(1):63-71.
Title:	Cetuximab-conjugated magneto-fluorescent silica nanoparticles for in vivo colon cancer targeting and imaging.
Author:	Cho, Young-Seok\|Yoon, Tae-Jong\|Jang, Eue-Soon\|Soo Hong, Kwan\|Young Lee, Shin\|Ran Kim, Ok\|Park, Cheongsoo\|Kim, Yong-Jin\|Yi, Gyu-Chul\|Chang, Kiyuk
PMID:	20826046

1002.
Journal:	Br J Cancer. 2010 Sep 28;103(7):1019-24.
Title:	Prognostic role of EGFR gene copy number and KRAS mutation in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy.
Author:	Bengala, C\|Bettelli, S\|Bertolini, F\|Sartori, G\|Fontana, A\|Malavasi, N\|Depenni, R\|Zironi, S\|Del Giovane, C\|Luppi, G\|Conte, P F
PMID:	20842128

1003.
Journal:	Vnitr Lek. 2010 Jul;56(7):709-14.
Title:	[Current options and principles of pathomorphology-based tumour diagnostics].
Author:	Povysil, C
PMID:	20842917

1004.
Journal:	J Exp Clin Cancer Res. 2010 Sep 15;29:125.
Title:	Chromogenic in situ hybridization to detect EGFR gene copy number in cell blocks from fine-needle aspirates of non small cell lung carcinomas and lung metastases from colo-rectal cancer.
Author:	Simone, Giovanni\|Mangia, Anita\|Malfettone, Andrea\|Rubini, Vincenza\|Siciliano, Michele\|Di Benedetto, Anna\|Terrenato, Irene\|Novelli, Flavia\|Mottolese, Marcella
PMID:	20843314

1005.
Journal:	Adv Clin Chem. 2010;51:71-119.
Title:	EGFR and KRAS in colorectal cancer.
Author:	Markman, Ben\|Javier Ramos, Francisco\|Capdevila, Jaume\|Tabernero, Josep
PMID:	20857619

1006.
Journal:	Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17604-9.
Title:	A mathematical framework to determine the temporal sequence of somatic genetic events in cancer.
Author:	Attolini, Camille Stephan-Otto\|Cheng, Yu-Kang\|Beroukhim, Rameen\|Getz, Gad\|Abdel-Wahab, Omar\|Levine, Ross L\|Mellinghoff, Ingo K\|Michor, Franziska
PMID:	20864632

1007.
Journal:	J Clin Oncol. 2010 Nov 1;28(31):4668-70.
Title:	EGFR antibodies in colorectal cancer: where do they belong?
Author:	Grothey, Axel
PMID:	20921457

1008.
Journal:	J Clin Oncol. 2010 Nov 1;28(31):4769-77.
Title:	Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
Author:	Roberts, Patrick J\|Stinchcombe, Thomas E\|Der, Channing J\|Socinski, Mark A
PMID:	20921461

1009.
Journal:	World J Gastroenterol. 2010 Oct 14;16(38):4823-31.
Title:	Tumor budding predicts response to anti-EGFR therapies in metastatic colorectal cancer patients.
Author:	Zlobec, Inti\|Molinari, Francesca\|Martin, Vittoria\|Mazzucchelli, Luca\|Saletti, Piercarlo\|Trezzi, Rosangela\|De Dosso, Sara\|Vlajnic, Tatjana\|Frattini, Milo\|Lugli, Alessandro
PMID:	20939111

1010.
Journal:	Mol Cancer. 2010 Oct 14;9:273.
Title:	Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.
Author:	Rigo, Antonella\|Gottardi, Michele\|Zamo, Alberto\|Mauri, Pierluigi\|Bonifacio, Massimiliano\|Krampera, Mauro\|Damiani, Ernesto\|Pizzolo, Giovanni\|Vinante, Fabrizio
PMID:	20946648

1011.
Journal:	Gastroenterol Clin North Am. 2010 Sep;39(3):601-13.
Title:	Targeted therapeutic agents for colorectal cancer.
Author:	Chee, Cheng E\|Sinicrope, Frank A
PMID:	20951919

1012.
Journal:	Nihon Rinsho. 2010 Oct;68(10):1866-70.
Title:	[Current status and perspectives of biologics in the treatment of metastatic colorectal cancer].
Author:	Takiuchi, Hiroya
PMID:	20954331

1013.
Journal:	Internist (Berl). 2010 Nov;51(11):1366-73.
Title:	[Multimodality therapy of colorectal cancer].
Author:	Hacker, U\|Hallek, M\|Kubicka, S
PMID:	20967408

1014.
Journal:	PLoS Curr. 2010 Oct 19;2:RRN1187.
Title:	BRAF p.Val600Glu (V600E) Testing for Assessment of Treatment Options in Metastatic Colorectal Cancer.
Author:	Lea, Andrew\|Allingham-Hawkins, Diane\|Levine, Susan
PMID:	20972475

1015.
Journal:	Anticancer Res. 2010 Oct;30(10):4209-17.
Title:	Molecular predictors of combination targeted therapies (cetuximab, bevacizumab) in irinotecan-refractory colorectal cancer (BOND-2 study).
Author:	Zhang, Wu\|Azuma, Mizutomo\|Lurje, Georg\|Gordon, Michael A\|Yang, Dongyun\|Pohl, Alexandra\|Ning, Yan\|Bohanes, Pierre\|Gerger, Armin\|Winder, Thomas\|Hollywood, Ellen\|Danenberg, Kathleen D\|Saltz, Leonard\|Lenz, Heinz-Josef
PMID:	21036743

1016.
Journal:	Anticancer Res. 2010 Oct;30(10):4229-35.
Title:	Concordant analysis of KRAS status in primary colon carcinoma and matched metastasis.
Author:	Mariani, Pascale\|Lae, Marick\|Degeorges, Armelle\|Cacheux, Wulfran\|Lappartient, Emmanuelle\|Margogne, Audrey\|Pierga, Jean-Yves\|Girre, Veronique\|Mignot, Laurent\|Falcou, Marie Christine\|Salmon, Remy-Jacques\|Delattre, Olivier\|De Cremoux, Patricia
PMID:	21036746

1017.
Journal:	Core Evid. 2010 Oct 21;5:61-76.
Title:	Panitumumab: the evidence for its use in the treatment of metastatic colorectal cancer.
Author:	Berardi, Rossana\|Onofri, Azzurra\|Pistelli, Mirco\|Maccaroni, Elena\|Scartozzi, Mario\|Pierantoni, Chiara\|Cascinu, Stefano
PMID:	21042543

1018.
Journal:	Lancet Oncol. 2010 Nov;11(11):1020-1.
Title:	Are we ready to restrict EGFR therapy to quadruple-negative colorectal cancer?
Author:	Hawkes, Eliza\|Cunningham, David
PMID:	21051017

1019.
Journal:	Diagn Mol Pathol. 2010 Dec;19(4):201-8.
Title:	High sensitivity of reverse-hybridization methodology in the detection of KRAS mutations from formalin-fixed paraffin-embedded colorectal cancer samples.
Author:	De Miglio, Maria Rosaria\|Mura, Antonica\|Uras, Maria Gabriela\|Manca, Alessandra\|Contini, Marcella\|Murgia, Luciano\|Zinellu, Angelo\|Sotgia, Salvatore\|Carru, Ciriaco\|Massarelli, Giovannino\|Cossu-Rocca, Paolo
PMID:	21052001

1020.
Journal:	J Cell Biochem. 2010 Dec 1;111(5):1082-6.
Title:	Activation of signal pathways and the resistance to anti-EGFR treatment in colorectal cancer.
Author:	Chen, Jiezhong\|Huang, Xu-Feng\|Katsifis, Andrew
PMID:	21053280

1021.
Journal:	Gan To Kagaku Ryoho. 2010 Nov;37(11):2189-91.
Title:	[Two cases of colorectal cancer patients with poor performance status who had unresectable liver metastasis effectively treated by cetuximab].
Author:	Osawa, Gakuji\|Yoshimatsu, Kazuhiko\|Yokomizo, Hajime\|Matsumoto, Atsuo\|Yano, Yuki\|Itagaki, Hiroko\|Otani, Taisuke\|Fujimoto, Takashi\|Umehara, Arihiro\|Ogawa, Kenji
PMID:	21084825

1022.
Journal:	PLoS One. 2010 Nov 12;5(11):e13978.
Title:	DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.
Author:	Berg, Marianne\|Danielsen, Stine A\|Ahlquist, Terje\|Merok, Marianne A\|Agesen, Trude H\|Vatn, Morten H\|Mala, Tom\|Sjo, Ole H\|Bakka, Arne\|Moberg, Ingvild\|Fetveit, Torunn\|Mathisen, Oystein\|Husby, Anders\|Sandvik, Oddvar\|Nesbakken, Arild\|Thiis-Evensen, Espen\|Lothe
PMID:	21103049

1023.
Journal:	Swiss Med Wkly. 2010 Nov 19;140:w13112.
Title:	Kras in metastatic colorectal cancer.
Author:	Wicki, Andreas\|Herrmann, Richard\|Christofori, Gerhard
PMID:	21104470

1024.
Journal:	BMC Clin Pathol. 2010 Nov 26;10:6.
Title:	COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma.
Author:	Pritchard, Colin C\|Akagi, Laura\|Reddy, Poluru L\|Joseph, Loren\|Tait, Jonathan F
PMID:	21110880

1025.
Journal:	Anticancer Res. 2010 Nov;30(11):4673-7.
Title:	Ras mutational status is a biomarker for resistance to EGFR inhibitors in colorectal carcinoma.
Author:	Dempke, Wolfram C M\|Heinemann, Volker
PMID:	21115922

1026.
Journal:	Cancer Treat Rev. 2010 Nov;36 Suppl 3:S56-61.
Title:	Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy?
Author:	Rizzo, Sergio\|Bronte, Giuseppe\|Fanale, Daniele\|Corsini, Lidia\|Silvestris, Nicola\|Santini, Daniele\|Gulotta, Gaspare\|Bazan, Viviana\|Gebbia, Nicola\|Fulfaro, Fabio\|Russo, Antonio
PMID:	21129611

1027.
Journal:	Br J Cancer. 2010 Dec 7;103(12):1765-72.
Title:	Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer.
Author:	Di Fiore, F\|Sesboue, R\|Michel, P\|Sabourin, J C\|Frebourg, T
PMID:	21139621

1028.
Journal:	Curr Oncol. 2010 Nov;17(6):39-45.
Title:	Consensus recommendations for the use of anti-egfr therapies in metastatic colorectal cancer.
Author:	Cripps, C\|Gill, S\|Ahmed, S\|Colwell, B\|Dowden, S\|Kennecke, H\|Maroun, J\|Samson, B\|Thirlwell, M\|Wong, R
PMID:	21151408

1029.
Journal:	J Korean Soc Coloproctol. 2010 Oct;26(5):339-46.
Title:	Relation of the expression of cyclooxygenase-2 in colorectal adenomas and adenocarcinomas to angiogenesis and prognosis.
Author:	Han, Yoon Dae\|Hong, Young Ki\|Kang, Jung Gu\|Choi, Yoon Jung\|Park, Chan Heun
PMID:	21152137

1030.
Journal:	Curr Opin Investig Drugs. 2010 Dec;11(12):1434-41.
Title:	Necitumumab, a fully human IgG1 mAb directed against the EGFR for the potential treatment of cancer.
Author:	Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	21154125

1031.
Journal:	Curr Opin Mol Ther. 2010 Dec;12(6):703-11.
Title:	Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials.
Author:	Zwierzina, Heinz\|Bardelli, Alberto\|Ciardiello, Fortunato\|Gariboldi, Manuela\|Hakansson, Leif\|Lambrechts, Diether\|Lind, Guro E\|Loeffler-Ragg, Judith\|Schmoll, Hans\|Siena, Salvatore\|Tabernero, Josep\|Van Cutsem, Eric
PMID:	21154162

1032.
Journal:	World J Gastroenterol. 2010 Dec 21;16(47):5965-74.
Title:	Multiplex RT-PCR-based detections of CEA, CK20 and EGFR in colorectal cancer patients.
Author:	Tsouma, Aikaterini\|Aggeli, Chrysanthi\|Lembessis, Panagiotis\|Zografos, George-N\|Korkolis, Dimitris-P\|Pectasides, Dimitrios\|Skondra, Maria\|Pissimissis, Nikolaos\|Tzonou, Anastasia\|Koutsilieris, Michael
PMID:	21157973

1033.
Journal:	Magy Onkol. 2010 Dec;54(4):383-94.
Title:	Predictive and prognostic factors in the complex treatment of patients with colorectal cancer.
Author:	Laszlo, Landherr
PMID:	21163770

1034.
Journal:	Prescrire Int. 2010 Oct;19(109):219-24.
Title:	Chemotherapy of metastatic colorectal cancer.
Author:
PMID:	21180382

1035.
Journal:	Rev Prat. 2010 Oct 20;60(8):1094-9.
Title:	[Targeted therapies in colorectal cancer].
Author:	Sablin, Marie-Paule\|Dreyer, Chantal\|Colichi, Camelia\|Bouattour, Mohamed\|Faivre, Sandrine
PMID:	21197741

1036.
Journal:	Bull Cancer. 2010 Dec;97(12):1441-52.
Title:	[Clinical significance of BRAF mutations in colorectal cancer].
Author:	Lievre, A\|Rouleau, E\|Buecher, B\|Mitry, E
PMID:	21220223

1037.
Journal:	Acta Gastroenterol Belg. 2010 Oct-Dec;73(4):497-503.
Title:	Accurate KRAS mutation testing for EGFR-targeted therapy in colorectal cancer: emphasis on the key role and responsibility of pathologists.
Author:	Hoorens, A\|Jouret-Mourin, A\|Sempoux, C\|Demetter, P\|De Hertogh, G\|Teugels, E
PMID:	21299161

1038.
Journal:	Tumori. 2010 Sep-Oct;96(5):713-20.
Title:	Combination effect of cetuximab with radiation in colorectal cancer cells.
Author:	Shin, Hye Kyung\|Kim, Mi-Sook\|Lee, Jin Kyung\|Lee, Seung-Sook\|Ji, Young Hoon\|Kim, Jong-Il\|Jeong, Jae-Hoon
PMID:	21302618

1039.
Journal:	Nano Res. 2010 Jan 1;3(3):222-233.
Title:	Multiplexed Five-Color Molecular Imaging of Cancer Cells and Tumor Tissues with Carbon Nanotube Raman Tags in the Near-Infrared.
Author:	Liu, Zhuang\|Tabakman, Scott\|Sherlock, Sarah\|Li, Xiaolin\|Chen, Zhuo\|Jiang, Kaili\|Fan, Shoushan\|Dai, Hongjie
PMID:	21442006

1040.
Journal:	Oncology. 2010;79(5-6):415-22.
Title:	Cetuximab plus FOLFOX-4 in untreated patients with advanced colorectal cancer: a Gruppo Oncologico dell'Italia Meridionale Multicenter phase II study.
Author:	Colucci, Giuseppe\|Giuliani, Francesco\|Garufi, Carlo\|Mattioli, Rodolfo\|Manzione, Luigi\|Russo, Antonio\|Lopez, Massimo\|Parrella, Paola\|Tommasi, Stefania\|Copetti, Massimiliano\|Daniele, Bruno\|Pisconti, Salvatore\|Tuveri, Guido\|Silvestris, Nicola\|Maiello, Evaris
PMID:	21474966

1041.
Journal:	Cancer Biomark. 2010-2011;8(2):61-5.
Title:	The EGFR R521K polymorphism influences the risk to develop colorectal cancer.
Author:	Martinelli, Marcella\|Ugolini, Giampaolo\|Scapoli, Luca\|Rivetti, Stefano\|Lauriola, Mattia\|Mattei, Gabriella\|Rosati, Giancarlo\|Montroni, Isacco\|Manaresi, Alessio\|Zattoni, Davide\|Taffurelli, Mario\|Solmi, Rossella
PMID:	21896992

1042.
Journal:	Cancer Biomark. 2010-2011;8(2):89-94.
Title:	LNA-based PCR clamping enrichment assay for the identification of KRAS mutations.
Author:	Efrati, Edna\|Elkin, Hela\|Peerless, Yehudit\|Sabo, Edmond\|Ben-Izhak, Ofer\|Hershkovitz, Dov
PMID:	21896996

1043.
Journal:	Cancer Biomark. 2010-2011;8(6):331-40.
Title:	KRAS mutation detection in Tunisian sporadic coloractal cancer patients with direct sequencing, high resolution melting and denaturating high performance liquid chromatography.
Author:	Karim, Bougatef\|Florence, Coulet\|Kamel, Rouissi\|Nadia, Kourda\|Ines, Omrane\|Raja, Marrakchi\|Sarra, Ben Jileni\|Florent, Soubrier\|Amel, Ben Ammar-Elgaaied
PMID:	22072121

1044.
Journal:	Ont Health Technol Assess Ser. 2010;10(23):1-57. Epub 2010 Dec 1.
Title:	Gene expression profiling for guiding adjuvant chemotherapy decisions in women with early breast cancer: an evidence-based and economic analysis.
Author:
PMID:	23074401

1045.
Journal:	Ont Health Technol Assess Ser. 2010;10(24):1-48. Epub 2010 Dec 1.
Title:	Epidermal Growth Factor Receptor Mutation (EGFR) Testing for Prediction of Response to EGFR-Targeting Tyrosine Kinase Inhibitor (TKI) Drugs in Patients with Advanced Non-Small-Cell Lung Cancer: An Evidence-Based Analysis.
Author:
PMID:	23074402

1046.
Journal:	Ont Health Technol Assess Ser. 2010;10(25):1-49. Epub 2010 Dec 1.
Title:	KRAS Testing for Anti-EGFR Therapy in Advanced Colorectal Cancer: An Evidence-Based and Economic Analysis.
Author:
PMID:	23074403

1047.
Journal:	Per Med. 2010 Jan;7(1):19-31.
Title:	Relating biomarkers to efficacy and the efficacy curve: a review of EGFR therapies in oncology.
Author:	Stroupe, Stephen D\|Colpitts, Tracey L
PMID:	29783375

1048.
Journal:	Invest New Drugs. 2011 Feb;29(1):167-74.
Title:	A phase II, multicenter study of cetuximab monotherapy in patients with refractory, metastatic colorectal carcinoma with absent epidermal growth factor receptor immunostaining.
Author:	Wierzbicki, Rafal\|Jonker, Derek J\|Moore, Malcolm J\|Berry, Scott R\|Loehrer, Patrick J\|Youssoufian, Hagop\|Rowinsky, Eric K
PMID:	19830388

1049.
Journal:	Crit Rev Oncol Hematol. 2011 Jan;77(1):78-84.
Title:	First-line single-agent cetuximab in elderly patients with metastatic colorectal cancer. A phase II clinical and molecular study of the Spanish group for digestive tumor therapy (TTD).
Author:	Sastre, J\|Aranda, E\|Gravalos, C\|Massuti, B\|Varella-Garcia, M\|Rivera, F\|Soler, G\|Carrato, A\|Manzano, J L\|Diaz-Rubio, E\|Hidalgo, M
PMID:	20042346

1050.
Journal:	Colorectal Dis. 2011 May;13(5):542-8.
Title:	Molecular detection of epidermal growth factor receptor in colorectal cancer: does it still make sense?
Author:	Nannini, M\|Pantaleo, M A\|Paterini, P\|Piazzi, G\|Ceccarelli, C\|La Rovere, S\|Maleddu, A\|Biasco, G
PMID:	20070321

1051.
Journal:	Invest New Drugs. 2011 Oct;29(5):1038-44.
Title:	A randomized phase II study of raltitrexed and gefitinib versus raltitrexed alone as second line chemotherapy in patients with colorectal cancer. (1839IL/0143).
Author:	Vieitez, Jose Maria\|Valladares, Manuel\|Pelaez, Ignacio\|de Sande Gonzalez, Luis\|Garcia-Foncillas, Jesus\|Garcia-Lopez, Jose Luis\|Garcia-Giron, Carlos\|Reboredo, Margarita\|Bovio, Humberto\|Lacave, Angel Jimenez
PMID:	20204674

1052.
Journal:	Int J Cancer. 2011 Feb 15;128(4):951-61.
Title:	Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.
Author:	Nautiyal, Jyoti\|Banerjee, Sanjeev\|Kanwar, Shailender S\|Yu, Yingjie\|Patel, Bhaumik B\|Sarkar, Fazlul H\|Majumdar, Adhip P N
PMID:	20473900

1053.
Journal:	Mol Biol Rep. 2011 Feb;38(2):1315-20.
Title:	KRAS, BRAF, EGFR and HER2 gene status in a Spanish population of colorectal cancer.
Author:	Herreros-Villanueva, Marta\|Rodrigo, Maximiliano\|Claver, Manuel\|Muniz, Pilar\|Lastra, Enrique\|Garcia-Giron, Carlos\|Coma del Corral, Maria Jesus
PMID:	20563851

1054.
Journal:	Mol Biol Rep. 2011 Feb;38(2):1347-51.
Title:	PIK3CA mutations in KRAS and BRAF wild type colorectal cancer patients. A study of Spanish population.
Author:	Herreros-Villanueva, Marta\|Gomez-Manero, Noemi\|Muniz, Pilar\|Garcia-Giron, Carlos\|Coma del Corral, Maria Jesus
PMID:	20571907

1055.
Journal:	Diagn Cytopathol. 2011 Apr;39(4):274-7.
Title:	KRAS testing on colo-rectal carcinoma cytological imprints.
Author:	Malapelle, Umberto\|Bellevicine, Claudio\|Russo, Anna\|Salatiello, Maria\|Palombini, Lucio\|Troncone, Giancarlo
PMID:	20607679

1056.
Journal:	Int J Cancer. 2011 May 1;128(9):2031-7.
Title:	Increased epidermal growth factor receptor expression at the invasive margin is a negative prognostic factor in colorectal cancer.
Author:	Ljuslinder, Ingrid\|Melin, Beatrice\|Henriksson, Maria L\|Oberg, Ake\|Palmqvist, Richard
PMID:	20635387

1057.
Journal:	Med Oncol. 2011 Dec;28(4):1048-53.
Title:	Distribution of some activating KRAS and BRAF mutations in Slovene patients with colorectal cancer.
Author:	Licar, Alenka\|Cerkovnik, Petra\|Novakovic, Srdjan
PMID:	20645028

1058.
Journal:	Cancer Treat Rev. 2011 Apr;37(2):151-9.
Title:	Use of molecular markers for predicting therapy response in cancer patients.
Author:	Duffy, Michael J\|O'Donovan, Norma\|Crown, John
PMID:	20685042

1059.
Journal:	Innate Immun. 2011 Aug;17(4):414-22.
Title:	Regulation of colon cancer cell proliferation and migration by MD-2 activity.
Author:	Grondin, Virginie\|Seksik, Philippe\|Dumont, Sylvie\|Thomas, Ginette\|Trugnan, Germain\|Flejou, Jean Francois\|Masliah, Joelle\|Wendum, Dominique\|Bachelet, Maria
PMID:	20699280

1060.
Journal:	Colorectal Dis. 2011 Sep;13(9):989-98.
Title:	Immunohistochemical analysis of tumour regression grade for rectal cancer after neoadjuvant chemoradiotherapy.
Author:	Garcia, V Moreno\|Batlle, J F\|Casado, E\|Burgos, E\|de Castro, J\|Belda, C\|Barriuso, J\|Sanchez, J J\|Garcia-Cabezas, M A\|Gonzalez-Baron, M\|Cejas, P
PMID:	20718834

1061.
Journal:	Am J Clin Dermatol. 2011 Feb 1;12(1):63-7.
Title:	Cetuximab-associated elongation of the eyelashes: case report and review of eyelash trichomegaly secondary to epidermal growth factor receptor inhibitors.
Author:	Cohen, Philip R\|Escudier, Susan M\|Kurzrock, Razelle
PMID:	20726623

1062.
Journal:	Cancer Treat Rev. 2011 May;37(3):221-33.
Title:	All about KRAS for clinical oncology practice: gene profile, clinical implications and laboratory recommendations for somatic mutational testing in colorectal cancer.
Author:	Linardou, Helena\|Briasoulis, Evangelos\|Dahabreh, Issa J\|Mountzios, Giannis\|Papadimitriou, Christos\|Papadopoulos, Savvas\|Bafaloukos, Dimitrios\|Kosmidis, Paris\|Murray, Samuel
PMID:	20817364

1063.
Journal:	Int J Cancer. 2011 Jun 15;128(12):2938-46.
Title:	EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer.
Author:	Ho-Pun-Cheung, Alexandre\|Assenat, Eric\|Bascoul-Mollevi, Caroline\|Bibeau, Frederic\|Boissiere-Michot, Florence\|Cellier, Dominic\|Azria, David\|Rouanet, Philippe\|Senesse, Pierre\|Ychou, Marc\|Lopez-Crapez, Evelyne
PMID:	20824716

1064.
Journal:	Oncogene. 2011 Feb 10;30(6):737-50.
Title:	Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling.
Author:	Kitajima, S\|Miki, T\|Takegami, Y\|Kido, Y\|Noda, M\|Hara, E\|Shamma, A\|Takahashi, C
PMID:	20890302

1065.
Journal:	Oncogene. 2011 Feb 3;30(5):561-74.
Title:	Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab.
Author:	Dunn, E F\|Iida, M\|Myers, R A\|Campbell, D A\|Hintz, K A\|Armstrong, E A\|Li, C\|Wheeler, D L
PMID:	20956938

1066.
Journal:	Cancer Chemother Pharmacol. 2011 Aug;68(2):317-23.
Title:	Clinical impact of K-ras mutation in colorectal cancer patients treated with adjuvant FOLFOX.
Author:	Chang, Myung Hee\|Lee, In Kyu\|Si, Yoon\|Lee, Kyu Sang\|Woo, In-Sook\|Byun, Jae Ho
PMID:	20972872

1067.
Journal:	Cancer Biol Ther. 2011 Jan 1;11(1):4-13. Epub 2011 Jan 1.
Title:	Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death.
Author:	Ametller, Elisabet\|Garcia-Recio, Susana\|Pastor-Arroyo, Eva-Maria\|Callejo, Gerard\|Carbo, Neus\|Gascon, Pedro\|Almendro, Vanessa
PMID:	20980803

1068.
Journal:	Cancer Biol Ther. 2011 Jan 15;11(2):196-203. Epub 2011 Jan 15.
Title:	An in vitro chemoresponse assay defines a subset of colorectal and lung carcinomas responsive to cetuximab.
Author:	Rice, Shara D\|Cassino, Theresa R\|Sakhamuri, Lahari\|Song, Nan\|Williams, Karl E\|Brower, Stacey L
PMID:	20980824

1069.
Journal:	Cytopathology. 2011 Dec;22(6):358-64.
Title:	KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma.
Author:	Pang, N K B\|Nga, M E\|Chin, S Y\|Ismail, T M\|Lim, G L\|Soong, R\|Salto-Tellez, M
PMID:	21029218

1070.
Journal:	J Clin Pathol. 2011 Jan;64(1):30-6.
Title:	Sensitive multiplex detection of KRAS codons 12 and 13 mutations in paraffin-embedded tissue specimens.
Author:	Laosinchai-Wolf, Walairat\|Ye, Fei\|Tran, Vu\|Yang, Zhe\|White, Roxanna\|Bloom, Kenneth\|Choppa, Paul\|Labourier, Emmanuel
PMID:	21030527

1071.
Journal:	Med Oncol. 2011 Dec;28 Suppl 1:S197-203.
Title:	Overexpression of SGLT1 and EGFR in colorectal cancer showing a correlation with the prognosis.
Author:	Guo, Gui Fang\|Cai, Yu Chen\|Zhang, Bei\|Xu, Rui Hua\|Qiu, Hui Juan\|Xia, Liang Ping\|Jiang, Wen Qi\|Hu, Pei Li\|Chen, Xu Xian\|Zhou, Fei Fei\|Wang, Fang
PMID:	21080109

1072.
Journal:	Phytother Res. 2011 Jun;25(6):833-7.
Title:	Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway.
Author:	Lee, Myung Sun\|Cha, Eun Young\|Sul, Ji Young\|Song, In Sang\|Kim, Ji Yeon
PMID:	21089180

1073.
Journal:	Clin Cancer Res. 2011 Feb 1;17(3):472-82.
Title:	HGF rescues colorectal cancer cells from EGFR inhibition via MET activation.
Author:	Liska, David\|Chen, Chin-Tung\|Bachleitner-Hofmann, Thomas\|Christensen, James G\|Weiser, Martin R
PMID:	21098338

1074.
Journal:	Cancer Biol Ther. 2011 Jan 15;11(2):177-83. Epub 2011 Jan 15.
Title:	Co-expression of matrix metalloproteinase-7 (MMP-7) and phosphorylated insulin growth factor receptor I (pIGF-1R) correlates with poor prognosis in patients with wild-type KRAS treated with cetuximab or panitumumab: a GEMCAD study.
Author:	Horndler, Carlos\|Gallego, Rosa\|Garcia-Albeniz, Xabier\|Alonso-Espinaco, Virginia\|Alonso, Vicente\|Escudero, Pilar\|Jimeno, Mireya\|Ortego, Javier\|Codony-Servat, Jordi\|Fernandez-Martos, Carlos\|Calatrava, Ana\|Marin-Aguilera, Mercedes\|Munoz, Jenifer\|Castellvi-Be
PMID:	21099348

1075.
Journal:	Tumour Biol. 2011 Apr;32(2):417-24.
Title:	Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab.
Author:	Garcia-Albeniz, Xabier\|Pericay, Carles\|Alonso-Espinaco, Virginia\|Alonso, Vicente\|Escudero, Pilar\|Fernandez-Martos, Carlos\|Gallego, Rosa\|Gascon, Pere\|Castellvi-Bel, Sergi\|Maurel, Joan
PMID:	21104178

1076.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G264-72.
Title:	Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells.
Author:	Qi, Wentao\|Weber, Christopher R\|Wasland, Kaarin\|Roy, Hemant\|Wali, Ramesh\|Joshi, Suhasini\|Savkovic, Suzana D
PMID:	21109589

1077.
Journal:	Oncol Rep. 2011 Jan;25(1):3-11.
Title:	EGFR, HER2 and HER3 expression in primary colorectal carcinomas and corresponding metastases: Implications for targeted radionuclide therapy.
Author:	Wei, Q\|Shui, Y\|Zheng, S\|Wester, K\|Nordgren, H\|Nygren, P\|Glimelius, B\|Carlsson, J
PMID:	21109951

1078.
Journal:	Oncol Rep. 2011 Jan;25(1):253-8.
Title:	Tissue sampling for mutation analysis in colorectal cancer: K-ras is homogeneously distributed throughout the tumor tissue.
Author:	Ekelund, Susanne\|Papadogiannakis, Nikos\|Olivecrona, Hans\|Lindforss, Ulrik
PMID:	21109984

1079.
Journal:	Cancer Res. 2011 Jan 15;71(2):445-53.
Title:	MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy.
Author:	Yoon, Juyong\|Koo, Kyoung-Hwa\|Choi, Kang-Yell
PMID:	21118963

1080.
Journal:	Mol Cancer Res. 2011 Feb;9(2):195-202.
Title:	GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway.
Author:	Pathi, Satya S\|Jutooru, Indira\|Chadalapaka, Gayathri\|Sreevalsan, Sandeep\|Anand, S\|Thatcher, Gregory Rj\|Safe, Stephen
PMID:	21156786

1081.
Journal:	Curr Cancer Drug Targets. 2011 Feb;11(2):190-8.
Title:	PI-3-Kinase inhibitors in colorectal cancer.
Author:	Ihle, N T\|Powis, G\|Kopetz, S
PMID:	21158718

1082.
Journal:	Pharm Res. 2011 Apr;28(4):827-38.
Title:	Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cells.
Author:	Kanwar, Shailender Singh\|Yu, Yingjie\|Nautiyal, Jyoti\|Patel, Bhaumik B\|Padhye, Subhash\|Sarkar, Fazlul H\|Majumdar, Adhip P N
PMID:	21161336

1083.
Journal:	Lancet Oncol. 2011 Jun;12(6):594-603.
Title:	KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.
Author:	De Roock, Wendy\|De Vriendt, Veerle\|Normanno, Nicola\|Ciardiello, Fortunato\|Tejpar, Sabine
PMID:	21163703

1084.
Journal:	Oncol Rep. 2011 Mar;25(3):789-94.
Title:	Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis.
Author:	Aoyagi, Haruhiko\|Iida, Satoru\|Uetake, Hiroyuki\|Ishikawa, Toshiaki\|Takagi, Yoko\|Kobayashi, Hirotoshi\|Higuchi, Tetsuro\|Yasuno, Masamichi\|Enomoto, Masayuki\|Sugihara, Kenichi
PMID:	21174064

1085.
Journal:	Cancer Treat Rev. 2011 Nov;37(7):533-42.
Title:	Targeted epidermal growth factor receptor therapy in malignant pleural mesothelioma: where do we stand?
Author:	Agarwal, Vijay\|Lind, Michael J\|Cawkwell, Lynn
PMID:	21183281

1086.
Journal:	Cancer Res. 2011 Mar 1;71(5):1520-5.
Title:	Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.
Author:	Fischer, Marcus\|Yen, Wan-Ching\|Kapoun, Ann M\|Wang, Min\|O'Young, Gilbert\|Lewicki, John\|Gurney, Austin\|Hoey, Timothy
PMID:	21193546

1087.
Journal:	Ann Intern Med. 2011 Jan 4;154(1):37-49.
Title:	Systematic review: Anti-epidermal growth factor receptor treatment effect modification by KRAS mutations in advanced colorectal cancer.
Author:	Dahabreh, Issa J\|Terasawa, Teruhiko\|Castaldi, Peter J\|Trikalinos, Thomas A
PMID:	21200037

1088.
Journal:	Oncologist. 2011;16(1):53-60.
Title:	The role of HER-3 expression in the prediction of clinical outcome for advanced colorectal cancer patients receiving irinotecan and cetuximab.
Author:	Scartozzi, Mario\|Mandolesi, Alessandra\|Giampieri, Riccardo\|Bittoni, Alessandro\|Pierantoni, Chiara\|Zaniboni, Alberto\|Galizia, Eva\|Giustini, Lucio\|Silva, Rosa Rita\|Bisonni, Renato\|Berardi, Rossana\|Biscotti, Tommasina\|Biagetti, Simona\|Bearzi, Italo\|Cascinu,
PMID:	21212430

1089.
Journal:	Nanomedicine. 2011 Aug;7(4):454-63.
Title:	Targeted human serum albumin nanoparticles for specific uptake in EGFR-Expressing colon carcinoma cells.
Author:	Low, Karin\|Wacker, Matthias\|Wagner, Sylvia\|Langer, Klaus\|von Briesen, Hagen
PMID:	21215330

1090.
Journal:	Am J Clin Oncol. 2011 Dec;34(6):581-6.
Title:	Dual blockade of the EGFR and COX-2 pathways: a phase II trial of cetuximab and celecoxib in patients with chemotherapy refractory metastatic colorectal cancer.
Author:	Chan, Emily\|Lafleur, Bonnie\|Rothenberg, Mace L\|Merchant, Nipun\|Lockhart, Albert Craig\|Trivedi, Bakula\|Chung, Christine H\|Coffey, Robert J\|Berlin, Jordan D
PMID:	21217396

1091.
Journal:	Pathology. 2011 Feb;43(2):133-7.
Title:	Loss of E-cadherin independently predicts the lymph node status in colorectal cancer.
Author:	Karamitopoulou, E\|Zlobec, I\|Patsouris, Es\|Peros, G\|Lugli, A
PMID:	21233674

1092.
Journal:	Lab Invest. 2011 May;91(5):788-98.
Title:	Rapid detection of low-abundance K-ras mutation in stools of colorectal cancer patients using chip-based temperature gradient capillary electrophoresis.
Author:	Zhang, Huidan\|Wang, Xiaonan\|Ma, Qian\|Zhou, Zhe\|Fang, Jin
PMID:	21242956

1093.
Journal:	Med Hypotheses. 2011 Apr;76(4):530-2.
Title:	Polyclonal antitumor immunoglobulin may play a role in ovarian cancer adjuvant therapy.
Author:	Tang, Lei\|Zhao, Xia
PMID:	21255939

1094.
Journal:	Int J Biol Macromol. 2011 Apr 1;48(3):511-7.
Title:	Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma.
Author:	Li, You-Gui\|Ji, Dong-Feng\|Zhong, Shi\|Zhu, Jian-Xun\|Chen, Shi\|Hu, Gui-Yan
PMID:	21262260

1095.
Journal:	Dtsch Med Wochenschr. 2011 Feb;136(5):179-81.
Title:	[Recent results of research on cancer of the colon, gastric cancer, sarcoma and bronchial carcinoma].
Author:	Hacker, U T\|Wolf, J\|Wendtner, C-M
PMID:	21271476

1096.
Journal:	Nanomedicine. 2011 Aug;7(4):480-8.
Title:	Cetuximab-labeled liposomes containing near-infrared probe for in vivo imaging.
Author:	Portnoy, Emma\|Lecht, Shimon\|Lazarovici, Philip\|Danino, Dganit\|Magdassi, Shlomo
PMID:	21272665

1097.
Journal:	Oncologist. 2011;16(2):228-38.
Title:	Management of skin toxicity associated with cetuximab treatment in combination with chemotherapy or radiotherapy.
Author:	Pinto, Carmine\|Barone, Carlo Antonio\|Girolomoni, Giampiero\|Russi, Elvio Grazioso\|Merlano, Marco Carlo\|Ferrari, Daris\|Maiello, Evaristo
PMID:	21273511

1098.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G749-60.
Title:	Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion.
Author:	Belo, Angelica\|Cheng, Kunrong\|Chahdi, Ahmed\|Shant, Jasleen\|Xie, Guofeng\|Khurana, Sandeep\|Raufman, Jean-Pierre
PMID:	21273532

1099.
Journal:	PLoS One. 2011 Jan 20;6(1):e15980.
Title:	Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in >/= 2 line cetuximab-based therapy of colorectal cancer patients.
Author:	Saridaki, Zacharenia\|Tzardi, Maria\|Papadaki, Chara\|Sfakianaki, Maria\|Pega, Fraga\|Kalikaki, Aristea\|Tsakalaki, Eleftheria\|Trypaki, Maria\|Messaritakis, Ippokratis\|Stathopoulos, Efstathios\|Mavroudis, Dimitris\|Georgoulias, Vassilis\|Souglakos, John
PMID:	21283802

1100.
Journal:	Br J Cancer. 2011 Mar 1;104(5):856-62.
Title:	BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer.
Author:	Yokota, T\|Ura, T\|Shibata, N\|Takahari, D\|Shitara, K\|Nomura, M\|Kondo, C\|Mizota, A\|Utsunomiya, S\|Muro, K\|Yatabe, Y
PMID:	21285991

1101.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title:	Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author:	Liu, Xin\|Guo, Wei-Jian\|Zhang, Xiao-Wei\|Cai, Xu\|Tian, Shu\|Li, Jin
PMID:	21286718

1102.
Journal:	Int J Colorectal Dis. 2011 Jul;26(7):823-33.
Title:	Cetuximab and panitumumab in KRAS wild-type colorectal cancer: a meta-analysis.
Author:	Petrelli, Fausto\|Borgonovo, Karen\|Cabiddu, Mary\|Ghilardi, Mara\|Barni, Sandro
PMID:	21286919

1103.
Journal:	Cancer Genomics Proteomics. 2011 Jan-Feb;8(1):15-8.
Title:	BRAF p.Val600Glu (V600E) somatic mutation is mainly associated with MSS phenotype in metastatic colorectal cancer.
Author:	Qiu, Jinghua\|Compagnone, Marion\|Laibe, Sophy\|Lagarde, Arnaud\|Goncalves, Anthony\|Turrini, Olivier\|Xerri, Luc\|Monges, Genevieve\|Olschwang, Sylviane
PMID:	21289333

1104.
Journal:	Genes Chromosomes Cancer. 2011 May;50(5):307-12.
Title:	Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
Author:	Vaughn, Cecily P\|Zobell, Scott D\|Furtado, Larissa V\|Baker, Christine L\|Samowitz, Wade S
PMID:	21305640

1105.
Journal:	Hum Pathol. 2011 Jul;42(7):1047-52.
Title:	A novel case of rhabdoid colon carcinoma associated with a positive CpG island methylator phenotype and BRAF mutation.
Author:	Pancione, Massimo\|Di Blasi, Arturo\|Sabatino, Lina\|Fucci, Alessandra\|Dalena, Anna Maria\|Palombi, Natalia\|Carotenuto, Pietro\|Aquino, Gabriella\|Daniele, Bruno\|Normanno, Nicola\|Colantuoni, Vittorio
PMID:	21315413

1106.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):1045-55.
Title:	Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer.
Author:	Park, Jin Hyun\|Han, Sae-Won\|Oh, Do-Youn\|Im, Seock-Ah\|Jeong, Seung-Yong\|Park, Kyu Joo\|Kim, Tae-You\|Bang, Yung-Jue\|Park, Jae-Gahb
PMID:	21340604

1107.
Journal:	Anticancer Drugs. 2011 Apr;22(4):330-40.
Title:	Antiepidermal growth factor receptor radiosensitizers in rectal cancer.
Author:	Glynne-Jones, Robert\|Mawdsley, Suzy\|Harrison, Mark
PMID:	21346551

1108.
Journal:	Discov Med. 2011 Feb;11(57):95-105.
Title:	The role of the epidermal growth factor receptor in the mechanism and treatment of colorectal cancer.
Author:	Yarom, Nirit\|Jonker, Derek J
PMID:	21356164

1109.
Journal:	Gan To Kagaku Ryoho. 2011 Feb;38(2):313-5.
Title:	[A case of advanced colon cancer successfully treated with cetuximab diagnosed as EGFR-positive by liver biopsy].
Author:	Tsuchida, Kazuhito\|Hayashi, Shigeya\|Sawazaki, Sho\|Jin, Yasuyuki\|Hasuo, Kimiatsu\|Suzuki, Hiroharu\|Hayashi, Hideo\|Omatsu, Mutsuko\|Rino, Yasushi\|Masuda, Munetaka
PMID:	21368503

1110.
Journal:	Int J Oncol. 2011 May;38(5):1365-73.
Title:	Lithium reduces tumorigenic potential in response to EGF signaling in human colorectal cancer cells.
Author:	Vidal, Flavia\|de Araujo, Wallace Martins\|Cruz, Andre L S\|Tanaka, Marcelo Neves\|Viola, Joao P B\|Morgado-Diaz, Jose A
PMID:	21369697

1111.
Journal:	Oncogene. 2011 Jul 21;30(29):3234-47.
Title:	Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.
Author:	Dhawan, P\|Ahmad, R\|Chaturvedi, R\|Smith, J J\|Midha, R\|Mittal, M K\|Krishnan, M\|Chen, X\|Eschrich, S\|Yeatman, T J\|Harris, R C\|Washington, M K\|Wilson, K T\|Beauchamp, R D\|Singh, A B
PMID:	21383692

1112.
Journal:	Patholog Res Int. 2011 Feb 14;2011:932932.
Title:	EGFR Signaling in Colorectal Carcinoma.
Author:	Krasinskas, Alyssa M
PMID:	21403829

1113.
Journal:	Cancer J. 2011 Mar-Apr;17(2):114-26.
Title:	Molecular predictors of response to chemotherapy in colorectal cancer.
Author:	Dienstmann, Rodrigo\|Vilar, Eduardo\|Tabernero, Josep
PMID:	21427555

1114.
Journal:	Curr Med Chem. 2011;18(11):1599-612.
Title:	Targeted therapy in colorectal cancer: current status and future challenges.
Author:	Koutras, A K\|Starakis, I\|Kyriakopoulou, U\|Katsaounis, P\|Nikolakopoulos, A\|Kalofonos, H P
PMID:	21428886

1115.
Journal:	Patholog Res Int. 2011 Mar 15;2011:219309.
Title:	Impact of KRAS Mutations on Management of Colorectal Carcinoma.
Author:	Sullivan, Kevin M\|Kozuch, Peter S
PMID:	21437184

1116.
Journal:	PLoS One. 2011 Mar 25;6(3):e18087.
Title:	HDAC inhibition decreases the expression of EGFR in colorectal cancer cells.
Author:	Chou, Chia-Wei\|Wu, Ming-Shiang\|Huang, Wei-Chien\|Chen, Ching-Chow
PMID:	21464950

1117.
Journal:	Mol Med Rep. 2011 Mar-Apr;4(2):203-8.
Title:	Role of genetic polymorphisms and mutations in colorectal cancer therapy (Review).
Author:	Aiello, Marco\|Vella, Nadia\|Cannavo, Calogero\|Scalisi, Aurora\|Spandidos, Demetrios A\|Toffoli, Giuseppe\|Buonadonna, Angela\|Libra, Massimo\|Stivala, Franca
PMID:	21468552

1118.
Journal:	Int J Surg Pathol. 2011 Apr;19(2):145-51.
Title:	Mutations in K-ras and epidermal growth factor receptor expression in Korean patients with stages III and IV colorectal cancer.
Author:	Lee, Won-Suk\|Baek, Jeong Heum\|Lee, Jung Nam\|Lee, Woon Kee
PMID:	21474505

1119.
Journal:	J Gastrointest Surg. 2011 Jun;15(6):942-57.
Title:	Phosphorylated insulin-like growth factor 1 receptor is implicated in resistance to the cytostatic effect of gefitinib in colorectal cancer cells.
Author:	Yang, Li\|Li, Jianjun\|Ran, Li\|Pan, Feng\|Zhao, Xiaoxin\|Ding, Zhenyu\|Chen, Yuying\|Peng, Qiuping\|Liang, Houjie
PMID:	21479670

1120.
Journal:	Acta Clin Belg. 2011 Jan-Feb;66(1):10-7.
Title:	Epidermal growth factor receptor targeted therapies for solid tumours.
Author:	Van den Eynde, M\|Baurain, J F\|Mazzeo, F\|Machiels, J P
PMID:	21485758

1121.
Journal:	Anticancer Res. 2011 Mar;31(3):1039-42.
Title:	Does erlotinib restore chemosensitivity to chemotherapy in pancreatic cancer? A case series.
Author:	Saif, M Wasif
PMID:	21498735

1122.
Journal:	Curr Biol. 2011 May 10;21(9):779-86.
Title:	Amphiregulin exosomes increase cancer cell invasion.
Author:	Higginbotham, James N\|Demory Beckler, Michelle\|Gephart, Jonathan D\|Franklin, Jeffrey L\|Bogatcheva, Galina\|Kremers, Gert-Jan\|Piston, David W\|Ayers, Gregory D\|McConnell, Russell E\|Tyska, Matthew J\|Coffey, Robert J
PMID:	21514161

1123.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2011 Jul;301(1):G1-8.
Title:	The "cryptic" mechanism of action of glucagon-like peptide-2.
Author:	Rowland, Katherine J\|Brubaker, Patricia L
PMID:	21527727

1124.
Journal:	Pathol Res Pract. 2011 Jun 15;207(6):399-402.
Title:	Morphological and molecular heterogeneity in colorectal neoplasms with K-RAS mutation. A report of two cases.
Author:	Bosmuller, Hans\|Kranewitter, Wolfgang\|Webersinke, Gerald\|Rumpold, Holger\|Hackl, Margit\|Fend, Falko
PMID:	21536390

1125.
Journal:	Mol Nutr Food Res. 2011 Jun;55(6):832-43.
Title:	Cancer chemoprevention with green tea catechins by targeting receptor tyrosine kinases.
Author:	Shimizu, Masahito\|Adachi, Seiji\|Masuda, Muneyuki\|Kozawa, Osamu\|Moriwaki, Hisataka
PMID:	21538846

1126.
Journal:	BMC Res Notes. 2011 May 10;4:140.
Title:	Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models.
Author:	Matsuo, Teppei\|Nishizuka, Satoshi S\|Ishida, Kazushige\|Iwaya, Takeshi\|Ikeda, Miyuki\|Wakabayashi, Go
PMID:	21554739

1127.
Journal:	Expert Opin Biol Ther. 2011 Jul;11(7):937-49.
Title:	Cetuximab in the treatment of patients with colorectal cancer.
Author:	Garrett, Christopher R\|Eng, Cathy
PMID:	21557708

1128.
Journal:	Clin Cancer Res. 2011 May 15;17(10):3469-77.
Title:	Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Author:	Grimminger, Peter P\|Danenberg, Peter\|Dellas, Kathrin\|Arnold, Dirk\|Rodel, Claus\|Machiels, Jean-Pascal\|Haustermans, Karin\|Debucquoy, Annelies\|Velenik, Vaneja\|Sempoux, Christine\|Bracko, Matej\|Holscher, Arnulf H\|Semrau, Robert\|Yang, Dongyun\|Danenberg, Kathlee
PMID:	21558395

1129.
Journal:	Br J Cancer. 2011 May 24;104(11):1786-90.
Title:	Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients.
Author:	Scartozzi, M\|Bearzi, I\|Mandolesi, A\|Giampieri, R\|Faloppi, L\|Galizia, E\|Loupakis, F\|Zaniboni, A\|Zorzi, F\|Biscotti, T\|Labianca, R\|Falcone, A\|Cascinu, S
PMID:	21559018

1130.
Journal:	Int J Colorectal Dis. 2011 Oct;26(10):1271-7.
Title:	Heterogeneous distribution of K-ras mutations in primary colon carcinomas: implications for EGFR-directed therapy.
Author:	Oltedal, Satu\|Aasprong, Ole Gunnar\|Moller, Jannicke H\|Korner, Hartwig\|Gilje, Bjornar\|Tjensvoll, Kjersti\|Birkemeyer, Elke M\|Heikkila, Reino\|Smaaland, Rune\|Nordgard, Oddmund
PMID:	21573767

1131.
Journal:	Clin Chim Acta. 2011 Aug 17;412(17-18):1578-81.
Title:	KRAS mutation detection in colorectal cancer by a commercially available gene chip array compares well with Sanger sequencing.
Author:	French, Deborah\|Smith, Andrew\|Powers, Martin P\|Wu, Alan H B
PMID:	21575616

1132.
Journal:	AJNR Am J Neuroradiol. 2011 Jun-Jul;32(6):1002-3.
Title:	Panitumumab (vectibix).
Author:	Gemmete, J J\|Mukherji, S K
PMID:	21596817

1133.
Journal:	Chem Biol Interact. 2011 Aug 15;193(1):43-9.
Title:	Antitumor effects of a novel benzonaphthofurandione derivative (8e) on the human colon cancer cells in vitro and in vivo through cell cycle arrest accompanied with the modulation of EGFR and mTOR signaling.
Author:	Chung, Hwa-Jin\|Rhee, Hee-Kyung\|Lee, Sang Kook\|Park Choo, Hea-Young
PMID:	21600193

1134.
Journal:	Int J Colorectal Dis. 2011 Oct;26(10):1241-8.
Title:	Multiple mutations in the Kras gene in colorectal cancer: review of the literature with two case reports.
Author:	Macedo, Mariana Petaccia\|Andrade, Louise De Brot\|Coudry, Renata\|Crespo, Rodrigo\|Gomes, Marina\|Lisboa, Bianca Cristina Garcia\|Aguiar, Samuel Jr\|Soares, Fernando Augusto\|Carraro, Dirce Maria\|Cunha, Isabela Werneck
PMID:	21603900

1135.
Journal:	Clin Colorectal Cancer. 2011 Mar 1;10(1):63-9.
Title:	Effect of KRAS mutational status in advanced colorectal cancer on the outcomes of anti-epidermal growth factor receptor monoclonal antibody therapy: a systematic review and meta-analysis.
Author:	Lin, Albert Y\|Buckley, Nicholas S\|Lu, An-Ting T\|Kouzminova, Natalia B\|Salpeter, Shelley R
PMID:	21609938

1136.
Journal:	Int J Oncol. 2011 Aug;39(2):483-91.
Title:	Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members.
Author:	Khelwatty, Said Abdullah\|Essapen, Sharadah\|Seddon, Alan M\|Modjtahedi, Helmout
PMID:	21617858

1137.
Journal:	Front Biosci (Elite Ed). 2011 Jun 1;3:879-87.
Title:	EGFR genomic alterations in cancer: prognostic and predictive values.
Author:	Bronte, Giuseppe\|Terrasi, Marianna\|Rizzo, Sergio\|Sivestris, Nicola\|Ficorella, Corrado\|Cajozzo, Massimo\|Di Gaudio, Francesca\|Gulotta, Gaspare\|Siragusa, Sergio\|Gebbia, Nicola\|Russo, Antonio
PMID:	21622099

1138.
Journal:	Clin Cancer Res. 2011 Jul 15;17(14):4901-14.
Title:	Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer.
Author:	Molinari, Francesca\|Felicioni, Lara\|Buscarino, Michela\|De Dosso, Sara\|Buttitta, Fiamma\|Malatesta, Sara\|Movilia, Alessandra\|Luoni, Marco\|Boldorini, Renzo\|Alabiso, Oscar\|Girlando, Salvatore\|Soini, Barbara\|Spitale, Alessandra\|Di Nicolantonio, Federica\|Salett
PMID:	21632860

1139.
Journal:	Lancet. 2011 Jun 18;377(9783):2103-14.
Title:	Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial.
Author:	Maughan, Timothy S\|Adams, Richard A\|Smith, Christopher G\|Meade, Angela M\|Seymour, Matthew T\|Wilson, Richard H\|Idziaszczyk, Shelley\|Harris, Rebecca\|Fisher, David\|Kenny, Sarah L\|Kay, Edward\|Mitchell, Jenna K\|Madi, Ayman\|Jasani, Bharat\|James, Michelle D\|Brid
PMID:	21641636

1140.
Journal:	J Biol Chem. 2011 Jul 22;286(29):26178-87.
Title:	Ultraviolet irradiation can induce evasion of colon cancer cells from stimulation of epidermal growth factor.
Author:	Adachi, Seiji\|Yasuda, Ichiro\|Nakashima, Masanori\|Yamauchi, Takahiro\|Kawaguchi, Junji\|Shimizu, Masahito\|Itani, Masahiko\|Nakamura, Momoko\|Nishii, Yumi\|Yoshioka, Takashi\|Hirose, Yoshinobu\|Okano, Yukio\|Moriwaki, Hisataka\|Kozawa, Osamu
PMID:	21646361

1141.
Journal:	J Clin Oncol. 2011 Jul 1;29(19):2675-82.
Title:	Impact of KRAS and BRAF Gene Mutation Status on Outcomes From the Phase III AGITG MAX Trial of Capecitabine Alone or in Combination With Bevacizumab and Mitomycin in Advanced Colorectal Cancer.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Weickhardt, Andrew\|Townsend, Amanda R\|Wrin, Joseph W\|Chua, Ann\|Shivasami, Aravind\|Cummins, Michelle M\|Murone, Carmel\|Tebbutt, Niall C
PMID:	21646616

1142.
Journal:	Mol Nutr Food Res. 2011 Oct;55(10):1523-32.
Title:	The inhibitory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on human colon cancer cells.
Author:	Qiu, Peiju\|Guan, Huashi\|Dong, Ping\|Guo, Shanshan\|Zheng, Jinkai\|Li, Shiming\|Chen, Yun\|Ho, Chi-Tang\|Pan, Min-Hsiung\|McClements, David Julian\|Xiao, Hang
PMID:	21648071

1143.
Journal:	Mol Cancer Res. 2011 Jul;9(7):960-75.
Title:	EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators.
Author:	Zhu, Hongyan\|Dougherty, Urszula\|Robinson, Victoria\|Mustafi, Reba\|Pekow, Joel\|Kupfer, Sonia\|Li, Yan-Chun\|Hart, John\|Goss, Kathleen\|Fichera, Alessandro\|Joseph, Loren\|Bissonnette, Marc
PMID:	21653642

1144.
Journal:	Sci Transl Med. 2011 Jun 8;3(86):86ra50.
Title:	Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Author:	Dolloff, Nathan G\|Mayes, Patrick A\|Hart, Lori S\|Dicker, David T\|Humphreys, Robin\|El-Deiry, Wafik S
PMID:	21653830

1145.
Journal:	J Cell Physiol. 2011 Sep;226(9):2316-28.
Title:	Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.
Author:	Irwin, Mary E\|Mueller, Kelly L\|Bohin, Natacha\|Ge, Yubin\|Boerner, Julie L
PMID:	21660955

1146.
Journal:	Hepatogastroenterology. 2011 Mar-Apr;58(106):411-6.
Title:	Heterogeneity in primary colorectal cancer and its corresponding metastases: a potential reason of EGFR-targeted therapy failure?
Author:	Li, Zhongqi\|Jin, Ketao\|Lan, Huanrong\|Teng, Lisong
PMID:	21661405

1147.
Journal:	Hum Pathol. 2011 Dec;42(12):1888-96.
Title:	Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.
Author:	Karamitopoulou, Eva\|Zlobec, Inti\|Panayiotides, Ioannis\|Patsouris, Efstratios S\|Peros, George\|Rallis, George\|Lapas, Christos\|Karakitsos, Petros\|Terracciano, Luigi M\|Lugli, Alessandro
PMID:	21664646

1148.
Journal:	Clin Cancer Res. 2011 Sep 1;17(17):5546-52.
Title:	Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
Author:	Montero, Juan Carlos\|Seoane, Samuel\|Ocana, Alberto\|Pandiella, Atanasio
PMID:	21670084

1149.
Journal:	J Surg Oncol. 2011 Nov 1;104(6):661-6.
Title:	The status of EGFR-associated genes could predict the outcome and tumor response of chemo-refractory metastatic colorectal patients using cetuximab and chemotherapy.
Author:	Lin, Jen-Kou\|Lin, An-Jen\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Yang, Shung-Haur\|Li, Anna Fen-Yau\|Chang, Shih-Ching
PMID:	21671463

1150.
Journal:	Gan To Kagaku Ryoho. 2011 Jun;38(6):901-6.
Title:	[Colorectal cancer chemotherapy and anti-EGFR therapy].
Author:	Tsuji, Akihito
PMID:	21677479

1151.
Journal:	Harefuah. 2011 May;150(5):447-50, 491.
Title:	[Identification of K-RAS mutations in colorectal cancer patients in Israel].
Author:	Segal, Gadi\|Liebermann, Nicky\|Klang, Shmuel\|Siegelmann-Daniel, Nava\|Beit-Or, Anat\|Klien, Baruch\|Shoushan-Gutman, Lior
PMID:	21678640

1152.
Journal:	Harefuah. 2011 May;150(5):451-2, 490.
Title:	[Personalized medicine--the future is already here].
Author:	Abadi-Korek, Ifat\|Shemer, Joshua
PMID:	21678641

1153.
Journal:	Br J Cancer. 2011 Jul 12;105(2):255-62.
Title:	EGFR gene copy number assessment from areas with highest EGFR expression predicts response to anti-EGFR therapy in colorectal cancer.
Author:	Algars, A\|Lintunen, M\|Carpen, O\|Ristamaki, R\|Sundstrom, J
PMID:	21694725

1154.
Journal:	Virchows Arch. 2011 Aug;459(2):155-60.
Title:	Mutation analysis of KRAS prior to targeted therapy in colorectal cancer: development and evaluation of quality by a European external quality assessment scheme.
Author:	Dequeker, Elisabeth\|Ligtenberg, Marjolijn J L\|Vander Borght, Sara\|van Krieken, Johan H J M
PMID:	21701884

1155.
Journal:	Lung Cancer. 2011 Oct;74(1):7-11.
Title:	Do all lung adenocarcinomas follow a stepwise progression?
Author:	Yatabe, Yasushi\|Borczuk, Alain C\|Powell, Charles A
PMID:	21705107

1156.
Journal:	Oncology (Williston Park). 2011 May;25(6):518-26, 529.
Title:	Targeting the insulin growth factor pathway in gastrointestinal cancers.
Author:	Golan, Talia\|Javle, Milind
PMID:	21717907

1157.
Journal:	Mol Cancer. 2011 Jul 3;10:79.
Title:	Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
Author:	Nakashima, Masanori\|Adachi, Seiji\|Yasuda, Ichiro\|Yamauchi, Takahiro\|Kawaguchi, Junji\|Hanamatsu, Toshimasa\|Yoshioka, Takashi\|Okano, Yukio\|Hirose, Yoshinobu\|Kozawa, Osamu\|Moriwaki, Hisataka
PMID:	21722395

1158.
Journal:	Radiother Oncol. 2011 Oct;101(1):140-6.
Title:	Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation.
Author:	Toulany, Mahmoud\|Schickfluss, Tim-Andre\|Fattah, Kazi R\|Lee, Kyung-Jong\|Chen, Benjamin P C\|Fehrenbacher, Birgit\|Schaller, Martin\|Chen, David J\|Rodemann, H Peter
PMID:	21723633

1159.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):325-32.
Title:	Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?
Author:	Inno, Alessandro\|Di Salvatore, Mariantonietta\|Cenci, Tonia\|Martini, Maurizio\|Orlandi, Armando\|Strippoli, Antonia\|Ferrara, Anna Maria\|Bagala, Cinzia\|Cassano, Alessandra\|Larocca, Luigi Maria\|Barone, Carlo
PMID:	21729677

1160.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):279-89.
Title:	Development of molecular biomarkers in individualized treatment of colorectal cancer.
Author:	De Mattos-Arruda, Leticia\|Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	21729679

1161.
Journal:	Dig Dis. 2011;29(2):222-8.
Title:	Colon cancer: a civilization disorder.
Author:	Watson, Alastair J M\|Collins, Paul D
PMID:	21734388

1162.
Journal:	Anticancer Res. 2011 Jun;31(6):2149-60.
Title:	Estimating preclinical efficacy targets utilizing cetuximab efficacy in KRAS mutant and wild-type colorectal cancer models.
Author:	Prewett, Marie\|Bassi, Rajiv\|Paz, Keren\|Amatulli, Michael\|Deevi, Dhanvanthri\|Li, Huiling\|Wang, Su\|Witte, Larry\|Samakoglu, Selda\|Tonra, James R
PMID:	21737635

1163.
Journal:	Anticancer Res. 2011 Jun;31(6):2271-81.
Title:	Phase II trial of weekly alternating sequential BIBF 1120 and afatinib for advanced colorectal cancer.
Author:	Bouche, Olivier\|Maindrault-Goebel, Frederique\|Ducreux, Michel\|Lledo, Gerard\|Andre, Thierry\|Stopfer, Peter\|Amellal, Nadia\|Merger, Michael\|De Gramont, Aimery
PMID:	21737652

1164.
Journal:	Clin Chim Acta. 2011 Sep 18;412(19-20):1874-8.
Title:	Differential detection of KRAS mutations in codons 12 and 13 with a modified loop-hybrid (LH) mobility shift assay using an insert-type LH-generator.
Author:	Matsukuma, Shoichi\|Yoshihara, Mitsuyo\|Suda, Tetsuji\|Shiozawa, Manabu\|Akaike, Makoto\|Ishikawa, Tomokazu\|Koizume, Shiro\|Sakuma, Yuji\|Miyagi, Yohei
PMID:	21741959

1165.
Journal:	Oncologist. 2011;16(9):1239-49.
Title:	Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: a review.
Author:	Baas, Jara M\|Krens, Lisanne L\|Guchelaar, Henk-Jan\|Morreau, Hans\|Gelderblom, Hans
PMID:	21742964

1166.
Journal:	Cas Lek Cesk. 2011;150(6):321-6.
Title:	[KRAS mutation testing in therapeutic algorithm for treatment of metastatic colorectal carcinoma].
Author:	Dubska, Lenka\|Vyskocilova, Martina\|Nenutil, Rudolf\|Valik, Dalibor\|Knoflickova, Dana\|Fabian, Pavel\|Kocakova, Ilona\|Demlova, Regina\|Beranek, Martin\|Drastikova, Monika\|Vosmikova, Hana\|Boday, Arpad\|Horka, Katerina\|Simova, Jarmila\|Drabek, Jiri\|Ehrmann, Jiri\|Ha
PMID:	21751504

1167.
Journal:	Gan To Kagaku Ryoho. 2011 Jul;38(7):1079-83.
Title:	[Predictive biomarkers of anti-EGFR monoclonal anti-body in colorectal cancer].
Author:	Soeda, Hiroshi\|Shimodaira, Hideki\|Ishioka, Chikashi
PMID:	21772090

1168.
Journal:	J Oncol. 2011;2011:125467.
Title:	The Role of EGFR Inhibitors in the Treatment of Metastatic Anal Canal Carcinoma: A Case Series.
Author:	Saif, Muhammad W\|Kontny, Ewa\|Syrigos, Kostas N\|Shahrokni, Armin
PMID:	21772841

1169.
Journal:	Biochem Biophys Res Commun. 2011 Aug 12;411(4):751-6.
Title:	Novel irreversible EGFR tyrosine kinase inhibitor 324674 sensitizes human colon carcinoma HT29 and SW480 cells to apoptosis by blocking the EGFR pathway.
Author:	Yu, Zhiwei\|Cui, Binbin\|Jin, Yinghu\|Chen, Haipeng\|Wang, Xishan
PMID:	21782788

1170.
Journal:	P T. 2011 May;36(5):263-79.
Title:	Roles of EGFR and KRAS Mutations in the Treatment Of Patients With Non-Small-Cell Lung Cancer.
Author:	Langer, Corey J
PMID:	21785539

1171.
Journal:	Clin Cancer Res. 2011 Sep 1;17(17):5668-73.
Title:	Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab.
Author:	Pander, Jan\|Heusinkveld, Moniek\|van der Straaten, Tahar\|Jordanova, Ekaterina S\|Baak-Pablo, Renee\|Gelderblom, Hans\|Morreau, Hans\|van der Burg, Sjoerd H\|Guchelaar, Henk-Jan\|van Hall, Thorbald
PMID:	21788356

1172.
Journal:	Mol Med Rep. 2011 Nov-Dec;4(6):1151-5.
Title:	The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma.
Author:	Ebi, Masahide\|Kataoka, Hiromi\|Shimura, Takaya\|Hirata, Yoshikazu\|Mizushima, Takashi\|Mizoshita, Tsutomu\|Tanaka, Mamoru\|Tsukamoto, Hironobu\|Ozeki, Keiji\|Tanida, Satoshi\|Kamiya, Takeshi\|Inagaki, Hiroshi\|Joh, Takashi
PMID:	21805036

1173.
Journal:	Semin Oncol. 2011 Aug;38(4):521-32.
Title:	From chemotherapy to targeted therapy in adjuvant treatment for stage III colon cancer.
Author:	de Gramont, Aimery\|de Gramont, Armand\|Chibaudel, Benoist\|Bachet, Jean-Baptiste\|Larsen, Annette K\|Tournigand, Christophe\|Louvet, Christophe\|Andre, Thierry
PMID:	21810511

1174.
Journal:	Semin Oncol. 2011 Aug;38(4):576-87.
Title:	Predictive molecular classifiers in colorectal cancer.
Author:	Bohanes, Pierre\|LaBonte, Melissa J\|Winder, Thomas\|Lenz, Heinz-Josef
PMID:	21810517

1175.
Journal:	Rinsho Byori. 2011 Jun;59(6):598-601.
Title:	[KRAS mutation test].
Author:	Hinoda, Yuji
PMID:	21815483

1176.
Journal:	J Korean Soc Coloproctol. 2011 Jun;27(3):127-32.
Title:	Epidermal growth factor receptor mutations in colorectal cancer patients.
Author:	Oh, Bo-Young\|Lee, Ryung-Ah\|Chung, Soon-Sup\|Kim, Kwang Ho
PMID:	21829767

1177.
Journal:	Diagn Cytopathol. 2011 Sep;39(9):703-10.
Title:	Cytology-based gene mutation tests to predict response to anti-epidermal growth factor receptor therapy: a review.
Author:	Malapelle, Umberto\|Bellevicine, Claudio\|Zeppa, Pio\|Palombini, Lucio\|Troncone, Giancarlo
PMID:	21837660

1178.
Journal:	Chin Med. 2011 Aug 23;6:31.
Title:	Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.
Author:	Mimeault, Murielle\|Batra, Surinder K
PMID:	21859497

1179.
Journal:	Anticancer Res. 2011 Sep;31(9):2971-4.
Title:	The efficacy of gemcitabine as salvage treatment in patients with refractory advanced colorectal cancer (CRC): a single institution experience.
Author:	Saif, Muhammad Wasif\|Kaley, Kristin\|Penney, Robin\|Hotchkiss, Susan\|Syrigos, Kostas N\|Strimpakos, Alexios S
PMID:	21868546

1180.
Journal:	Curr Oncol. 2011 Aug;18(4):e180-4.
Title:	Canadian Expert Group consensus recommendations: KRAS testing in colorectal cancer.
Author:	Aubin, F\|Gill, S\|Burkes, R\|Colwell, B\|Kamel-Reid, S\|Koski, S\|Pollett, A\|Samson, B\|Tehfe, M\|Wong, R\|Young, S\|Soulieres, D
PMID:	21874108

1181.
Journal:	Pak J Biol Sci. 2011 Mar 1;14(5):357-62.
Title:	Expression of membranous epidermal growth factor receptor in colorectal adenocarcinoma and its correlation with clinicopathological features.
Author:	Mohammadi, G\|Jamialahmadi, K\|Lary, S\|Ghaffarzadegan, K
PMID:	21874828

1182.
Journal:	Clin Cancer Res. 2011 Oct 15;17(20):6522-30.
Title:	EGFR- and VEGF(R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies.
Author:	Poindessous, Virginie\|Ouaret, Djamila\|El Ouadrani, Karima\|Battistella, Aude\|Megalophonos, Virginie F\|Kamsu-Kom, Nyam\|Petitprez, Amelie\|Escargueil, Alexandre E\|Boudou, Pascaline\|Dumont, Sylvie\|Cervera, Pascale\|Flejou, Jean-Francois\|Andre, Thierry\|Tournigan
PMID:	21880790

1183.
Journal:	Clin Cancer Res. 2011 Oct 15;17(20):6531-41.
Title:	Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers.
Author:	Rosa, Roberta\|Melisi, Davide\|Damiano, Vincenzo\|Bianco, Roberto\|Garofalo, Sonia\|Gelardi, Teresa\|Agrawal, Sudhir\|Di Nicolantonio, Federica\|Scarpa, Aldo\|Bardelli, Alberto\|Tortora, Giampaolo
PMID:	21890455

1184.
Journal:	Oncology. 2011;81(1):3-8.
Title:	KRAS mutation in metastatic pancreatic ductal adenocarcinoma: results of a multicenter phase II study evaluating efficacy of cetuximab plus gemcitabine/oxaliplatin (GEMOXCET) in first-line therapy.
Author:	Kullmann, F\|Hartmann, A\|Stohr, R\|Messmann, H\|Dollinger, M M\|Trojan, J\|Fuchs, M\|Hollerbach, S\|Harder, J\|Troppmann, M\|Kutscheidt, A\|Endlicher, E
PMID:	21894049

1185.
Journal:	J Clin Oncol. 2011 Oct 1;29(28):3783-90.
Title:	Phase I pharmacokinetic and pharmacodynamic dose-escalation study of RG7160 (GA201), the first glycoengineered monoclonal antibody against the epidermal growth factor receptor, in patients with advanced solid tumors.
Author:	Paz-Ares, Luis G\|Gomez-Roca, Carlos\|Delord, Jean-Pierre\|Cervantes, Andres\|Markman, Ben\|Corral, Jesus\|Soria, Jean-Charles\|Berge, Yann\|Roda, Desamparados\|Russell-Yarde, Fiona\|Hollingsworth, Simon\|Baselga, Jose\|Umana, Pablo\|Manenti, Luigi\|Tabernero, Josep
PMID:	21900113

1186.
Journal:	Sci Transl Med. 2011 Sep 7;3(99):99ra86.
Title:	Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.
Author:	Yonesaka, Kimio\|Zejnullahu, Kreshnik\|Okamoto, Isamu\|Satoh, Taroh\|Cappuzzo, Federico\|Souglakos, John\|Ercan, Dalia\|Rogers, Andrew\|Roncalli, Massimo\|Takeda, Masayuki\|Fujisaka, Yasuhito\|Philips, Juliet\|Shimizu, Toshio\|Maenishi, Osamu\|Cho, Yonggon\|Sun, Jason\|D
PMID:	21900593

1187.
Journal:	Gan To Kagaku Ryoho. 2011 Sep;38(9):1396-402.
Title:	[The present situation regarding postoperative adjuvant chemotherapy].
Author:	Shimada, Ryu\|Nozawa, Keijirou\|Watanabe, Toshiaki
PMID:	21918334

1188.
Journal:	Exp Cell Res. 2011 Nov 15;317(19):2765-71.
Title:	EGFR-targeted therapy.
Author:	Vecchione, Loredana\|Jacobs, Bart\|Normanno, Nicola\|Ciardiello, Fortunato\|Tejpar, Sabine
PMID:	21925171

1189.
Journal:	Hepatogastroenterology. 2011 Jul-Aug;58(109):1182-8.
Title:	The significance of a group of molecular markers and clinicopathological factors in identifying colorectal liver metastasis.
Author:	Wu, Jian-Hui\|Tian, Xiu-Yun\|Hao, Chun-Yi
PMID:	21937374

1190.
Journal:	Rinsho Byori. 2011 Aug;59(8):757-62.
Title:	[Tm analysis method using a quenching probe is a simple and rapid way to simultaneously detect KRAS and BRAF mutations].
Author:	Akagi, Kiwamu\|Arai, Yoshiko
PMID:	21942085

1191.
Journal:	West Indian Med J. 2011 Mar;60(2):107-13.
Title:	The effect of combining interferon-alpha and gefitinib in human colon cancer cell lines.
Author:	Yang, Li\|Wang, Fang\|He, Fang\|Huang, LiYa
PMID:	21942111

1192.
Journal:	Nutr J. 2011 Sep 26;10:99.
Title:	Bioactive properties and clinical safety of a novel milk protein peptide.
Author:	Kreider, Richard B\|Iosia, Mike\|Cooke, Matt\|Hudson, Geoffrey\|Rasmussen, Chris\|Chen, Helen\|Mollstedt, Olof\|Tsai, Men-Hwei
PMID:	21943352

1193.
Journal:	BMC Cancer. 2011 Sep 24;11:406.
Title:	Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing.
Author:	Borras, Emma\|Jurado, Ismael\|Hernan, Imma\|Gamundi, Maria Jose\|Dias, Miguel\|Marti, Isabel\|Mane, Begona\|Arcusa, Angels\|Agundez, Jose A G\|Blanca, Miguel\|Carballo, Miguel
PMID:	21943394

1194.
Journal:	Biochem Biophys Res Commun. 2011 Oct 14;414(1):118-22.
Title:	Neurotensin-induced Erk1/2 phosphorylation and growth of human colonic cancer cells are independent from growth factors receptors activation.
Author:	Massa, Fabienne\|Tormo, Aurelie\|Beraud-Dufour, Sophie\|Coppola, Thierry\|Mazella, Jean
PMID:	21945442

1195.
Journal:	Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17135-40.
Title:	Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/beta-catenin signaling.
Author:	Scholer-Dahirel, Alix\|Schlabach, Michael R\|Loo, Alice\|Bagdasarian, Linda\|Meyer, Ronald\|Guo, Ribo\|Woolfenden, Steve\|Yu, Kristine K\|Markovits, Judit\|Killary, Karen\|Sonkin, Dmitry\|Yao, Yung-Mae\|Warmuth, Markus\|Sellers, William R\|Schlegel, Robert\|Stegmeier, F
PMID:	21949247

1196.
Journal:	BMC Cancer. 2011 Oct 2;11:421.
Title:	Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.
Author:	Muller, Kristin M\|Tveteraas, Ingun H\|Aasrum, Monica\|Odegard, John\|Dawood, Mona\|Dajani, Olav\|Christoffersen, Thoralf\|Sandnes, Dagny L
PMID:	21961726

1197.
Journal:	Arch Pathol Lab Med. 2011 Oct;135(10):1278-82.
Title:	Epidermal growth factor receptor pathway mutations and colorectal cancer therapy.
Author:	Grossmann, Allie H\|Samowitz, Wade S
PMID:	21970483

1198.
Journal:	Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3):639-49.
Title:	Gene expression profile of human colon cancer cells treated with cross-reacting material 197, a diphtheria toxin non-toxic mutant.
Author:	Rivetti, S\|Lauriola, M\|Voltattorni, M\|Bianchini, M\|Martini, D\|Ceccarelli, C\|Palmieri, A\|Mattei, G\|Franchi, M\|Ugolini, G\|Rosati, G\|Montroni, I\|Taffurelli, M\|Solmi, Rossella
PMID:	21978696

1199.
Journal:	Expert Rev Anticancer Ther. 2011 Oct;11(10):1499-503.
Title:	Anti-EGFR therapy in first-line colorectal cancer.
Author:	Lamas, Maria J\|Duran, Goretti\|Gallardo, Elena
PMID:	21999123

1200.
Journal:	Expert Rev Anticancer Ther. 2011 Oct;11(10):1543-53.
Title:	Where now for anti-EGF receptor therapies in colorectal cancer?
Author:	Shaw, Paul H S\|Adams, Richard A
PMID:	21999128

1201.
Journal:	Virchows Arch. 2011 Nov;459(5):487-93.
Title:	Molecular morphometric analysis shows relative intra-tumoural homogeneity for KRAS mutations in colorectal cancer.
Author:	Farber, Liora\|Efrati, Edna\|Elkin, Hela\|Peerless, Yehudit\|Sabo, Edmond\|Ben-Izhak, Ofer\|Hershkovitz, Dov
PMID:	22016105

1202.
Journal:	BMC Med Genet. 2011 Oct 25;12:144.
Title:	The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain.
Author:	Metzger, Brigitte\|Chambeau, Laetitia\|Begon, Dominique Y\|Faber, Carlo\|Kayser, Jacques\|Berchem, Guy\|Pauly, Marc\|Boniver, Jacques\|Delvenne, Philippe\|Dicato, Mario\|Wenner, Thomas
PMID:	22026926

1203.
Journal:	Br J Cancer. 2011 Nov 22;105(11):1759-67.
Title:	Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells.
Author:	Bose, D\|Zimmerman, L J\|Pierobon, M\|Petricoin, E\|Tozzi, F\|Parikh, A\|Fan, F\|Dallas, N\|Xia, L\|Gaur, P\|Samuel, S\|Liebler, D C\|Ellis, L M
PMID:	22045189

1204.
Journal:	BMC Complement Altern Med. 2011 Nov 9;11:111.
Title:	American ginseng suppresses Western diet-promoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR.
Author:	Dougherty, Urszula\|Mustafi, Reba\|Wang, Yunwei\|Musch, Mark W\|Wang, Chong-Zhi\|Konda, Vani J\|Kulkarni, Anirudh\|Hart, John\|Dawson, Glyn\|Kim, Karen E\|Yuan, Chun-Su\|Chang, Eugene B\|Bissonnette, Marc
PMID:	22070864

1205.
Journal:	J Drug Target. 2011 Dec;19(10):933-43.
Title:	Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer.
Author:	Kopansky, Eva\|Shamay, Yosi\|David, Ayelet
PMID:	22074249

1206.
Journal:	BMC Cancer. 2011 Nov 25;11:496.
Title:	Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer.
Author:	Dahan, Laetitia\|Norguet, Emmanuelle\|Etienne-Grimaldi, Marie-Christine\|Formento, Jean-Louis\|Gasmi, Mohamed\|Nanni, Isabelle\|Gaudart, Jean\|Garcia, Stephane\|Ouafik, L'Houcine\|Seitz, Jean-Francois\|Milano, Gerard
PMID:	22117530

1207.
Journal:	Discov Med. 2011 Nov;12(66):419-32.
Title:	The nuclear epidermal growth factor receptor signaling network and its role in cancer.
Author:	Brand, Toni M\|Iida, Mari\|Li, Chunrong\|Wheeler, Deric L
PMID:	22127113

1208.
Journal:	Cesk Patol. 2011 Oct;47(4):154-8.
Title:	[Molecular predictive markers of EGFR-targeted therapy in metastatic colorectal cancer].
Author:	Fabian, P\|Berkovcova, J
PMID:	22145213

1209.
Journal:	World J Gastroenterol. 2011 Nov 28;17(44):4858-66.
Title:	Erlotinib inhibits progression to dysplasia in a colitis-associated colon cancer model.
Author:	Pagan, Beatriz\|Isidro, Angel A\|Cruz, Myrella L\|Ren, Yuan\|Coppola, Domenico\|Wu, Jie\|Appleyard, Caroline B
PMID:	22171126

1210.
Journal:	PLoS One. 2011;6(12):e28841.
Title:	Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors.
Author:	Morgillo, Floriana\|Martinelli, Erika\|Troiani, Teresa\|Orditura, Michele\|De Vita, Ferdinando\|Ciardiello, Fortunato
PMID:	22174910

1211.
Journal:	PLoS One. 2011;6(12):e29060.
Title:	Regulation of cysteinyl leukotriene receptor 2 expression--a potential anti-tumor mechanism.
Author:	Magnusson, Cecilia\|Bengtsson, Astrid M\|Liu, Minghui\|Liu, Jian\|Ceder, Yvonne\|Ehrnstrom, Roy\|Sjolander, Anita
PMID:	22194989

1212.
Journal:	Mol Cell. 2011 Dec 23;44(6):893-906.
Title:	Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.
Author:	Matallanas, David\|Romano, David\|Al-Mulla, Fahd\|O'Neill, Eric\|Al-Ali, Waleed\|Crespo, Piero\|Doyle, Brendan\|Nixon, Colin\|Sansom, Owen\|Drosten, Matthias\|Barbacid, Mariano\|Kolch, Walter
PMID:	22195963

1213.
Journal:	Int J Mol Epidemiol Genet. 2011;2(4):300-15. Epub 2011 Dec 3.
Title:	Genetic variability in EGFR, Src and HER2 and risk of colorectal adenoma and cancer.
Author:	Poole, Elizabeth M\|Curtin, Karen\|Hsu, Li\|Kulmacz, Richard J\|Duggan, David J\|Makar, Karen W\|Xiao, Liren\|Carlson, Christopher S\|Slattery, Martha L\|Caan, Bette J\|Potter, John D\|Ulrich, Cornelia M
PMID:	22199994

1214.
Journal:	Gan To Kagaku Ryoho. 2011 Nov;38(12):2244-6.
Title:	[Three cases of patients in their eighties who received anti-EGFR antibody mono-therapy as first-line treatment for metastatic colorectal cancer].
Author:	Katsumoto, Yoshihiro\|Aritake, Noriko\|Endoh, Akira\|Ueda, Naoki\|Inami, Naokuni
PMID:	22202343

1215.
Journal:	PLoS One. 2011;6(12):e29146.
Title:	KRAS mutations testing in colorectal carcinoma patients in Italy: from guidelines to external quality assessment.
Author:	Normanno, Nicola\|Pinto, Carmine\|Castiglione, Francesca\|Bardelli, Alberto\|Gambacorta, Marcello\|Botti, Gerardo\|Nappi, Oscar\|Siena, Salvatore\|Ciardiello, Fortunato\|Taddei, Gianluigi\|Marchetti, Antonio
PMID:	22216189

1216.
Journal:	Rev Esp Enferm Dig. 2011 Dec;103(12):632-9.
Title:	Epidermal growth factor receptor overexpression/amplification in adenocarcinomas arising in the gastrointestinal tract.
Author:	Rossi, Elisa\|Villanacci, Vincenzo\|Danesino, Cesare\|Donato, Francesco\|Nascimbeni, Riccardo\|Bassotti, Gabrio
PMID:	22217347

1217.
Journal:	Oncology. 2011;81(5-6):359-64.
Title:	Clinical and economic aspects of KRAS mutational status as predictor for epidermal growth factor receptor inhibitor therapy in metastatic colorectal cancer patients.
Author:	Konigsberg, Robert\|Hulla, Wolfgang\|Klimpfinger, Martin\|Reiner-Concin, Angelika\|Steininger, Tanja\|Buchler, Wilfried\|Terkola, Robert\|Dittrich, Christian
PMID:	22248908

1218.
Journal:	Folia Histochem Cytobiol. 2011;49(4):570-8.
Title:	Digital pathology in personalized cancer therapy.
Author:	Slodkowska, Janina\|Rojo, Marcial Garcia
PMID:	22252751

1219.
Journal:	Klin Onkol. 2011;24(6):465-9.
Title:	[The role of chemotherapy and targeted antiVEGF- and antiEGFR-therapy in metastatic colorectal cancer: a case report of long-term and intensive response].
Author:	Nemecek, R\|Vyzula, R
PMID:	22257237

1220.
Journal:	Zhonghua Yi Xue Za Zhi. 2011 Sep 6;91(33):2333-5.
Title:	[Phase I study of anti-EGFR monoclonal antibody (CMAB009) in patients with advanced cancer].
Author:	He, Xiao-Hui\|Shi, Yuan-Kai\|Qin, Yan\|Yang, Sheng\|Sun, Yan
PMID:	22321747

1221.
Journal:	Lijec Vjesn. 2011 Nov-Dec;133(11-12):403-7.
Title:	[The role of KRAS gene mutation testing in colorectal cancer--a predictive biomarker of response to EGFR inhibitors therapy].
Author:	Rako, Ivana\|Jakic-Razumovic, Jasminka\|Caban, Domagoj\|Sertic, Jadranka\|Katalinic, Darko\|Golem, Hilda\|Plestina, Stjepko
PMID:	22329297

1222.
Journal:	Cancer Discov. 2011 Nov;1(6):472-4.
Title:	HER2 signaling and resistance to the anti-EGFR monoclonal antibody cetuximab: a further step toward personalized medicine for patients with colorectal cancer.
Author:	Ciardiello, Fortunato\|Normanno, Nicola
PMID:	22586650

1223.
Journal:	Cancer Discov. 2011 Nov;1(6):508-23.
Title:	A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Author:	Bertotti, Andrea\|Migliardi, Giorgia\|Galimi, Francesco\|Sassi, Francesco\|Torti, Davide\|Isella, Claudio\|Cora, Davide\|Di Nicolantonio, Federica\|Buscarino, Michela\|Petti, Consalvo\|Ribero, Dario\|Russolillo, Nadia\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alber
PMID:	22586653

1224.
Journal:	Expert Opin Med Diagn. 2011 Mar;5(2):91-4.
Title:	Models of partnership between the pharmaceutical and diagnostics industries around companion diagnostics for cancer and beyond.
Author:	Ensinger, Christian
PMID:	23480583

1225.
Journal:	Cancers (Basel). 2011 Apr 26;3(2):2176-94.
Title:	Predictive factors of the response of rectal cancer to neoadjuvant radiochemotherapy.
Author:	Spolverato, Gaya\|Pucciarelli, Salvatore\|Bertorelle, Roberta\|De Rossi, Anita\|Nitti, Donato
PMID:	24212803

1226.
Journal:	Cancers (Basel). 2011 Aug 2;3(3):3104-13.
Title:	Toll-like receptor 4 signaling integrates intestinal inflammation with tumorigenesis: lessons from the murine model of colitis-associated cancer.
Author:	Hernandez, Yasmin\|Sotolongo, John\|Fukata, Masayuki
PMID:	24212947

1227.
Journal:	Gastroenterol Hepatol Bed Bench. 2011 Spring;4(2):70-5.
Title:	The role of kras mutations and MSI status in diagnosis of colorectal cancer.
Author:	Shemirani, Atena Irani\|Haghighi, Mahdi Montazer\|Milanizadeh, Saman\|Taleghani, Mohammad Yaghoob\|Fatemi, Seyed Reza\|Damavand, Behzad\|Akbari, Zahra\|Zali, Mohammad Reza
PMID:	24834160

1228.
Journal:	Gastroenterol Hepatol Bed Bench. 2011 Summer;4(3):127-32.
Title:	Colorectal cancer and NF-kappaB signaling pathway.
Author:	Hassanzadeh, Parichehr
PMID:	24834170

1229.
Journal:	Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):138-44.
Title:	X-ray cross-complementing group 1 and thymidylate synthase polymorphisms might predict response to chemoradiotherapy in rectal cancer patients.
Author:	Lamas, Maria J\|Duran, Goretti\|Gomez, Antonio\|Balboa, Emilia\|Anido, Urbano\|Bernardez, Beatriz\|Rana-Diez, Pablo\|Lopez, Rafael\|Carracedo, Angel\|Barros, Francisco
PMID:	21167658

1230.
Journal:	Cancer Treat Rev. 2012 Feb;38(1):63-7.
Title:	Critical comments for roles of biomarkers in the diagnosis and treatment of cancer.
Author:	Saijo, Nagahiro
PMID:	21652149

1231.
Journal:	Bull Cancer. 2012 Feb 1;99(2):181-9.
Title:	[EGFR/HER1: a target life].
Author:	Viel, Erika\|Curtit, Elsa\|Mansi, Laura\|Vignot, Stephane
PMID:	21684835

1232.
Journal:	Invest New Drugs. 2012 Aug;30(4):1607-13.
Title:	Biweekly cetuximab plus irinotecan as second-line chemotherapy for patients with irinotecan-refractory and KRAS wild-type metastatic colorectal cancer according to epidermal growth factor receptor expression status.
Author:	Kang, Myoung Joo\|Hong, Yong Sang\|Kim, Kyu-pyo\|Kim, Sun Young\|Baek, Ji Yeon\|Ryu, Min-Hee\|Lee, Jae-Lyun\|Chang, Heung Moon\|Kim, Mi-Jung\|Chang, Hee Jin\|Kang, Yoon-Koo\|Kim, Tae Won
PMID:	21706149

1233.
Journal:	Int J Oncol. 2012 Jan;40(1):176-84.
Title:	The effect of a dimeric Affibody molecule (ZEGFR:1907)2 targeting EGFR in combination with radiation in colon cancer cell lines.
Author:	Haggblad Sahlberg, Sara\|Spiegelberg, Diana\|Lennartsson, Johan\|Nygren, Peter\|Glimelius, Bengt\|Stenerlow, Bo
PMID:	21879255

1234.
Journal:	Cancer Chemother Pharmacol. 2012 Mar;69(3):577-90.
Title:	Pharmacodynamics of DT-IgG, a dual-targeting antibody against VEGF-EGFR, in tumor xenografted mice.
Author:	Hurwitz, Selwyn J\|Zhang, Hongzheng\|Yun, Sujin\|Batuwangala, Thil D\|Steward, Michael\|Holmes, Steve D\|Rycroft, Daniel\|Pan, Lin\|Tighiouart, Mourad\|Shin, Hyung Ju C\|Koenig, Lydia\|Wang, Yuxiang\|Chen, Zhuo Georgia\|Shin, Dong M
PMID:	21913035

1235.
Journal:	Cell Signal. 2012 Jan;24(1):162-9.
Title:	Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells.
Author:	Wang, Jaw-Yuan\|Chen, Ben-Kuen\|Wang, Yu-Shiuan\|Tsai, Yao-Ting\|Chen, Wei-Chiao\|Chang, Wen-Chang\|Hou, Ming-Feng\|Wu, Yang-Chang\|Chang, Wei-Chiao
PMID:	21924350

1236.
Journal:	Clin Colorectal Cancer. 2012 Mar;11(1):14-23.
Title:	Panitumumab in combination with cytotoxic chemotherapy for the treatment of metastatic colorectal carcinoma.
Author:	Peeters, Marc\|Cohn, Allen\|Kohne, Claus-Henning\|Douillard, Jean-Yves
PMID:	21925954

1237.
Journal:	Acta Oncol. 2012 Feb;51(2):231-3.
Title:	Capecitabine and bevacizumab in heavily pre-treated patients with advanced colorectal cancer.
Author:	Larsen, Finn Ole\|Boisen, Mogens Karsbol\|Fromm, Annelene L\|Jensen, Benny Vittrup
PMID:	21936753

1238.
Journal:	Cancer Sci. 2012 Jan;103(1):7-16.
Title:	Susceptibility to natural killer cell-mediated lysis of colon cancer cells is enhanced by treatment with epidermal growth factor receptor inhibitors through UL16-binding protein-1 induction.
Author:	Bae, Jae-Ho\|Kim, So-Jung\|Kim, Mi-Ju\|Oh, Sae-Ock\|Chung, Joo-Seop\|Kim, Sun-Hee\|Kang, Chi-Dug
PMID:	21951556

1239.
Journal:	Oncogene. 2012 May 31;31(22):2761-72.
Title:	BAG-1 interacts with the p50-p50 homodimeric NF-kappaB complex: implications for colorectal carcinogenesis.
Author:	Southern, S L\|Collard, T J\|Urban, B C\|Skeen, V R\|Smartt, H J\|Hague, A\|Oakley, F\|Townsend, P A\|Perkins, N D\|Paraskeva, C\|Williams, A C
PMID:	21963853

1240.
Journal:	Int J Oncol. 2012 Feb;40(2):378-84.
Title:	Detection of KRAS mutations in colorectal cancer with Fast COLD-PCR.
Author:	Carotenuto, Pietro\|Roma, Cristin\|Cozzolino, Salvatore\|Fenizia, Francesca\|Rachiglio, Anna Maria\|Tatangelo, Fabiana\|Iannaccone, Alessia\|Baron, Luigi\|Botti, Gerardo\|Normanno, Nicola
PMID:	21971641

1241.
Journal:	J Gastrointest Cancer. 2012 Sep;43(3):444-55.
Title:	Expression of EGFR, HER2, phosphorylated ERK and phosphorylated MEK in colonic neoplasms of familial adenomatous polyposis patients.
Author:	Wang, Jayson\|Hollingshead, James\|El-Masry, Nabil\|Horncastle, Donna\|Talbot, Ian\|Tomlinson, Ian\|Alison, Malcolm R\|El-Bahrawy, Mona
PMID:	21989899

1242.
Journal:	Ann Oncol. 2012 Jun;23(6):1518-25.
Title:	PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis.
Author:	Mao, C\|Yang, Z Y\|Hu, X F\|Chen, Q\|Tang, J L
PMID:	22039088

1243.
Journal:	Anticancer Agents Med Chem. 2012 Feb;12(2):163-71.
Title:	Are KRAS/BRAF mutations potent prognostic and/or predictive biomarkers in colorectal cancers?
Author:	Yokota, Tomoya
PMID:	22043994

1244.
Journal:	FEBS J. 2012 Jan;279(2):251-63.
Title:	EphrinA5 suppresses colon cancer development by negatively regulating epidermal growth factor receptor stability.
Author:	Wang, Tong-Hong\|Chang, Junn-Liang\|Ho, Jar-Yi\|Wu, Hsiao-Chun\|Chen, Tse-Ching
PMID:	22074469

1245.
Journal:	Ann Oncol. 2012 Jul;23(7):1706-12.
Title:	Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer patients receiving irinotecan-cetuximab.
Author:	Scartozzi, M\|Giampieri, R\|Maccaroni, E\|Mandolesi, A\|Giustini, L\|Silva, R\|Zaniboni, A\|Biscotti, T\|Biagetti, S\|Galizia, E\|Loupakis, F\|Falcone, A\|Bearzi, I\|Cascinu, S
PMID:	22112971

1246.
Journal:	Cancer Treat Rev. 2012 Oct;38(6):618-25.
Title:	Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis.
Author:	Vale, Claire L\|Tierney, Jayne F\|Fisher, David\|Adams, Richard A\|Kaplan, Richard\|Maughan, Timothy S\|Parmar, Mahesh K B\|Meade, Angela M
PMID:	22118887

1247.
Journal:	Cancer Sci. 2012 Mar;103(3):600-5.
Title:	Predicting cetuximab accumulation in KRAS wild-type and KRAS mutant colorectal cancer using 64Cu-labeled cetuximab positron emission tomography.
Author:	Achmad, Arifudin\|Hanaoka, Hirofumi\|Yoshioka, Hiroki\|Yamamoto, Shinji\|Tominaga, Hideyuki\|Araki, Takuya\|Ohshima, Yasuhiro\|Oriuchi, Noboru\|Endo, Keigo
PMID:	22126621

1248.
Journal:	J Clin Pathol. 2012 Mar;65(3):218-23.
Title:	Standardisation of EGFR FISH in colorectal cancer: results of an international interlaboratory reproducibility ring study.
Author:	Sartore-Bianchi, Andrea\|Fieuws, Steffen\|Veronese, Silvio\|Moroni, Mauro\|Personeni, Nicola\|Frattini, Milo\|Torri, Valter\|Cappuzzo, Federico\|Vander Borght, Sara\|Martin, Vittoria\|Skokan, Margaret\|Santoro, Armando\|Gambacorta, Marcello\|Tejpar, Sabine\|Varella-Gar
PMID:	22130903

1249.
Journal:	Mol Biol Rep. 2012 May;39(5):5387-91.
Title:	No evidence for PML-RARa bcr1 fusion gene in colorectal cancer.
Author:	Herreros-Villanueva, Marta
PMID:	22167334

1250.
Journal:	Clin Colorectal Cancer. 2012 Jun;11(2):85-7.
Title:	To give or not to give anti-epidermal growth factor receptor (EGFR) monoclonal antibodies to patients with KRAS G13D mutation in advanced colorectal cancer.
Author:	Kim, Richard\|Kubal, Timothy
PMID:	22169039

1251.
Journal:	Clin Cancer Res. 2012 Feb 1;18(3):688-99.
Title:	Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment.
Author:	Vermaat, Joost S\|Nijman, Isaac J\|Koudijs, Marco J\|Gerritse, Frank L\|Scherer, Stefan J\|Mokry, Michal\|Roessingh, Wijnand M\|Lansu, Nico\|de Bruijn, Ewart\|van Hillegersberg, Richard\|van Diest, Paul J\|Cuppen, Edwin\|Voest, Emile E
PMID:	22173549

1252.
Journal:	Mol Oncol. 2012 Feb;6(1):15-26.
Title:	Drug development to overcome resistance to EGFR inhibitors in lung and colorectal cancer.
Author:	Dienstmann, Rodrigo\|De Dosso, Sara\|Felip, Enriqueta\|Tabernero, Josep
PMID:	22189054

1253.
Journal:	Clin Chem. 2012 Mar;58(3):580-9.
Title:	COLD-PCR enrichment of rare cancer mutations prior to targeted amplicon resequencing.
Author:	Milbury, Coren A\|Correll, Mick\|Quackenbush, John\|Rubio, Renee\|Makrigiorgos, G Mike
PMID:	22194627

1254.
Journal:	Front Biosci (Elite Ed). 2012 Jan 1;4:12-22.
Title:	Role of anti-EGFR target therapy in colorectal carcinoma.
Author:	Enrique, Aranda-Aguilar\|Gema, Pulido-Cortijo\|Jeronimo, Jimenez-Castro\|Auxiliadora, Gomez-Espana Maria
PMID:	22201852

1255.
Journal:	Arch Pathol Lab Med. 2012 Jan;136(1):26-32.
Title:	Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma.
Author:	Kamel-Reid, Suzanne\|Zhang, Tong\|Persons, Diane L\|Nikiforova, Marina N\|Halling, Kevin C
PMID:	22208484

1256.
Journal:	Oncologist. 2012;17(1):13.
Title:	Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101.
Author:	Chiorean, E Gabriela\|Ramasubbaiah, Rashmi\|Yu, Menggang\|Picus, Joel\|Bufill, Jose A\|Tong, Yan\|Coleman, Nicki\|Johnston, Erica L\|Currie, Colleen\|Loehrer, Patrick J
PMID:	22210086

1257.
Journal:	Oncologist. 2012;17(1):14.
Title:	Panitumumab in patients with KRAS wild-type colorectal cancer after progression on cetuximab.
Author:	Wadlow, Raymond C\|Hezel, Aram F\|Abrams, Thomas A\|Blaszkowsky, Lawrence S\|Fuchs, Charles S\|Kulke, Matthew H\|Kwak, Eunice L\|Meyerhardt, Jeffrey A\|Ryan, David P\|Szymonifka, Jackie\|Wolpin, Brian M\|Zhu, Andrew X\|Clark, Jeffrey W
PMID:	22210091

1258.
Journal:	J Nucl Med. 2012 Jan;53(1):113-20.
Title:	PET and MRI of metastatic peritoneal and pulmonary colorectal cancer in mice with human epidermal growth factor receptor 1-targeted 89Zr-labeled panitumumab.
Author:	Nayak, Tapan K\|Garmestani, Kayhan\|Milenic, Diane E\|Brechbiel, Martin W
PMID:	22213822

1259.
Journal:	Curr Cancer Drug Targets. 2012 Feb;12(2):124-31.
Title:	Analysis of the concordance in the EGFR pathway status between primary tumors and related metastases of colorectal cancer patients:implications for cancer therapy.
Author:	Cejas, P\|Lopez-Gomez, M\|Aguayo, C\|Madero, R\|Moreno-Rubio, J\|de Castro Carpeno, J\|Belda-Iniesta, C\|Barriuso, J\|Moreno Garcia, V\|Diaz, E\|Burgos, E\|Gonzalez-Baron, M\|Feliu, J
PMID:	22229245

1260.
Journal:	Cancer Biol Ther. 2012 Feb 1;13(3):130-7.
Title:	Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer.
Author:	Rinella, Erica S\|Bankaitis, Eric D\|Threadgill, David W
PMID:	22231407

1261.
Journal:	Cell Cycle. 2012 Feb 1;11(3):594-603.
Title:	mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors.
Author:	Zhang, Yanjie\|Zheng, X F Steven
PMID:	22262166

1262.
Journal:	Biochem Pharmacol. 2012 Apr 1;83(7):849-57.
Title:	Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells.
Author:	Park, Jung-Jin\|Yi, Jae Youn\|Jin, Yeung Bae\|Lee, Yoon-Jin\|Lee, Jae-Seon\|Lee, Yun-Sil\|Ko, Young-Gyu\|Lee, Minyoung
PMID:	22266356

1263.
Journal:	Nat Med. 2012 Jan 22;18(2):221-3.
Title:	Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer.
Author:	Montagut, Clara\|Dalmases, Alba\|Bellosillo, Beatriz\|Crespo, Marta\|Pairet, Silvia\|Iglesias, Mar\|Salido, Marta\|Gallen, Manuel\|Marsters, Scot\|Tsai, Siao Ping\|Minoche, Andre\|Seshagiri, Somasekar\|Serrano, Sergi\|Himmelbauer, Heinz\|Bellmunt, Joaquim\|Rovira, Ana\|S
PMID:	22270724

1264.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2012 Apr;302(7):G655-63.
Title:	EGFR regulation of colon cancer stem-like cells during aging and in response to the colonic carcinogen dimethylhydrazine.
Author:	Nautiyal, Jyoti\|Du, Jianhua\|Yu, Yingjie\|Kanwar, Shailender S\|Levi, Edi\|Majumdar, Adhip P N
PMID:	22281474

1265.
Journal:	Nature. 2012 Jan 26;483(7387):100-3.
Title:	Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.
Author:	Prahallad, Anirudh\|Sun, Chong\|Huang, Sidong\|Di Nicolantonio, Federica\|Salazar, Ramon\|Zecchin, Davide\|Beijersbergen, Roderick L\|Bardelli, Alberto\|Bernards, Rene
PMID:	22281684

1266.
Journal:	Cancer. 2012 Aug 15;118(16):3882-92.
Title:	Exploring biomarkers in head and neck cancer.
Author:	Langer, Corey J
PMID:	22281752

1267.
Journal:	Clin Colorectal Cancer. 2012 Jun;11(2):143-50.
Title:	PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer.
Author:	Sood, Arjun\|McClain, Danielle\|Maitra, Radhashree\|Basu-Mallick, Atrayee\|Seetharam, Raviraja\|Kaubisch, Andreas\|Rajdev, Lakshmi\|Mariadason, John M\|Tanaka, Kathryn\|Goel, Sanjay
PMID:	22285706

1268.
Journal:	Diagn Mol Pathol. 2012 Mar;21(1):9-13.
Title:	Comparison of a PNA clamp PCR and an ARMS/Scorpion PCR assay for the detection of K-ras mutations.
Author:	Nordgard, Oddmund\|Oltedal, Satu\|Janssen, Emiel A M\|Gilje, Bjornar\|Korner, Hartwig\|Tjensvoll, Kjersti\|Smaaland, Rune
PMID:	22306670

1269.
Journal:	Diagn Mol Pathol. 2012 Mar;21(1):14-23.
Title:	KRAS mutation testing in colorectal cancer: comparison of the results obtained using 3 different methods for the analysis of codons G12 and G13.
Author:	Bihl, Michel P\|Hoeller, Sylvia\|Andreozzi, Maria Carla\|Foerster, Anja\|Rufle, Alexander\|Tornillo, Luigi\|Terracciano, Luigi
PMID:	22306671

1270.
Journal:	Cancer Biol Ther. 2012 Mar;13(5):289-95.
Title:	CIP2A overexpression is associated with c-Myc expression in colorectal cancer.
Author:	Bockelman, Camilla\|Koskensalo, Selja\|Hagstrom, Jaana\|Lundin, Mikael\|Ristimaki, Ari\|Haglund, Caj
PMID:	22310977

1271.
Journal:	Cancer Sci. 2012 Apr;103(4):791-6.
Title:	Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild-type colorectal cancer patients treated with cetuximab-based chemotherapy.
Author:	Hsieh, Yao-Yu\|Tzeng, Cheng-Hwai\|Chen, Ming-Huang\|Chen, Po-Min\|Wang, Wei-Shu
PMID:	22321154

1272.
Journal:	Gan To Kagaku Ryoho. 2012 Feb;39(2):311-5.
Title:	[Pathologically complete response for unresectable stage IV rectal cancer using systemic chemotherapy with panitumumab - a case report].
Author:	Bamba, Takeo\|Suda, Takeyasu\|Nakano, Masato\|Terashima, Tetsuro\|Umezu, Hajime
PMID:	22333651

1273.
Journal:	Cancer Lett. 2012 Aug 28;321(2):187-94.
Title:	The decrease of cell membrane fluidity by the non-steroidal anti-inflammatory drug Licofelone inhibits epidermal growth factor receptor signalling and triggers apoptosis in HCA-7 colon cancer cells.
Author:	Tavolari, Simona\|Munarini, Alessandra\|Storci, Gianluca\|Laufer, Stefan\|Chieco, Pasquale\|Guarnieri, Tiziana
PMID:	22343320

1274.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G1006-15.
Title:	Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation.
Author:	Xie, Guofeng\|Peng, Zhongsheng\|Raufman, Jean-Pierre
PMID:	22361730

1275.
Journal:	Jpn J Clin Oncol. 2012 Apr;42(4):278-86.
Title:	Safety, efficacy and pharmacokinetics of neratinib (HKI-272) in Japanese patients with advanced solid tumors: a Phase 1 dose-escalation study.
Author:	Ito, Yoshinori\|Suenaga, Mitsukuni\|Hatake, Kiyohiko\|Takahashi, Shunji\|Yokoyama, Masahiro\|Onozawa, Yusuke\|Yamazaki, Kentaro\|Hironaka, Shuichi\|Hashigami, Kiyoshi\|Hasegawa, Hirotaka\|Takenaka, Nobuko\|Boku, Narikazu
PMID:	22371427

1276.
Journal:	Curr Cancer Drug Targets. 2012 May;12(4):316-28.
Title:	Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond.
Author:	Ballestrero, A\|Garuti, A\|Cirmena, G\|Rocco, I\|Palermo, C\|Nencioni, A\|Scabini, S\|Zoppoli, G\|Parodi, S\|Patrone, F
PMID:	22385512

1277.
Journal:	Curr Cancer Drug Targets. 2012 May;12(4):356-71.
Title:	DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.
Author:	Solier, S\|Zhang, Y-W\|Ballestrero, A\|Pommier, Y\|Zoppoli, G
PMID:	22385513

1278.
Journal:	Clin Cancer Res. 2012 May 1;18(9):2515-25.
Title:	Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Author:	Migliardi, Giorgia\|Sassi, Francesco\|Torti, Davide\|Galimi, Francesco\|Zanella, Eugenia R\|Buscarino, Michela\|Ribero, Dario\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alberto\|Risio, Mauro\|Capussotti, Lorenzo\|Marsoni, Silvia\|Di Nicolantonio, Federica\|Bardelli,
PMID:	22392911

1279.
Journal:	Anticancer Res. 2012 Mar;32(3):783-6.
Title:	Cetuximab sensitivity associated with oxaliplatin resistance in colorectal cancer.
Author:	Ekblad, Lars\|Johnsson, Anders
PMID:	22399593

1280.
Journal:	Clin Med Insights Oncol. 2012;6:125-35.
Title:	Long-term treatment of metastatic colorectal cancer with panitumumab.
Author:	Lopez-Gomez, Miriam\|Merino, Maria\|Casado, Enrique
PMID:	22408376

1281.
Journal:	BMC Cancer. 2012 Mar 13;12:88.
Title:	Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases.
Author:	Kuramochi, Hidekazu\|Nakajima, Go\|Kaneko, Yuka\|Nakamura, Ayako\|Inoue, Yuji\|Yamamoto, Masakazu\|Hayashi, Kazuhiko
PMID:	22409860

1282.
Journal:	Hepatogastroenterology. 2012 Jun;59(116):1091-7.
Title:	Correlations between clinicopathological parameters and molecular signatures of primary tumors for patients with stage T3n0 colorectal adenocarcinomas: a single center retrospective study on 100 cases.
Author:	Andras, Csilla\|Toth, Laszlo\|Molnar, Csaba\|Tanyi, Miklos\|Csiki, Zoltan\|Dezso, Balazs\|Posan, Janos\|Shemirani, Amir-Houshang\|Csiki, Emese\|Szanto, Janos
PMID:	22414548

1283.
Journal:	J Mol Diagn. 2012 May-Jun;14(3):187-91.
Title:	Implementation of formalin-fixed, paraffin-embedded cell line pellets as high-quality process controls in quality assessment programs for KRAS mutation analysis.
Author:	Dijkstra, Jeroen R\|Opdam, Frank J M\|Boonyaratanakornkit, Jerry\|Schonbrunner, E Ralf\|Shahbazian, Mona\|Edsjo, Anders\|Hoefler, Gerald\|Jung, Andreas\|Kotsinas, Athanassios\|Gorgoulis, Vassilis G\|Lopez-Rios, Fernando\|de Stricker, Karin\|Rouleau, Etienne\|Biesmans,
PMID:	22414609

1284.
Journal:	Int J Biol Markers. 2012 Jan-Mar;27(1):27-33.
Title:	Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma.
Author:	Bagadi, Sarita B\|Sanghvi, Meera\|Nair, Sudish B\|Das, Bibhu R
PMID:	22427190

1285.
Journal:	Oncol Rep. 2012 Jun;27(6):1887-92.
Title:	Transcriptional upregulation of HER2 expression in the absence of HER2 gene amplification results in cetuximab resistance that is reversed by trastuzumab treatment.
Author:	Oliveras-Ferraros, Cristina\|Massaguer Vall-Llovera, Anna\|Vazquez-Martin, Alejandro\|Salip, Dolors Carrion\|Queralt, Bernardo\|Cufi, Silvia\|Martin-Castillo, Begona\|Bosch-Barrera, Joaquim\|Brunet, Joan\|De Llorens, Rafael\|Menendez, Javier A
PMID:	22427198

1286.
Journal:	Oncology. 2012;82(3):153-64.
Title:	Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition.
Author:	Fernandez-Marcelo, Tamara\|Moran, Alberto\|de Juan, Carmen\|Pascua, Irene\|Head, Jacqueline\|Gomez, Ana\|Hernando, Florentino\|Lopez-Asenjo, Jose A\|Hernandez, Susana\|Sanchez-Pernaute, Andres\|Torres, Antonio J\|Benito, Manuel\|Iniesta, Pilar
PMID:	22433385

1287.
Journal:	Diagn Pathol. 2012 Mar 21;7:29.
Title:	Effect of image compression and scaling on automated scoring of immunohistochemical stainings and segmentation of tumor epithelium.
Author:	Konsti, Juho\|Lundin, Mikael\|Linder, Nina\|Haglund, Caj\|Blomqvist, Carl\|Nevanlinna, Heli\|Aaltonen, Kirsimari\|Nordling, Stig\|Lundin, Johan
PMID:	22436596

1288.
Journal:	BMC Cancer. 2012 Mar 22;12:108.
Title:	A phase II study for metabolic in vivo response monitoring with sequential 18FDG-PET-CT during treatment with the EGFR-monoclonal-antibody cetuximab in metastatic colorectal cancer: the Heidelberg REMOTUX trial.
Author:	Berger, Anne Katrin\|von Gall, Carl\|Abel, Ulrich\|Delorme, Stefan\|Kloor, Matthias\|Ose, Jennifer\|Weber, Tim Frederik\|Stange, Annika\|Haag, Georg Martin\|Haberkorn, Uwe\|Lordick, Florian\|Jager, Dirk
PMID:	22439666

1289.
Journal:	Eur J Cancer. 2012 May;48(7):1108-15.
Title:	Concordance in KRAS and BRAF mutations in endoscopic biopsy samples and resection specimens of colorectal adenocarcinoma.
Author:	Krol, L C\|'t Hart, N A\|Methorst, N\|Knol, A J\|Prinsen, C\|Boers, J E
PMID:	22446020

1290.
Journal:	Cancer Discov. 2012 Mar;2(3):227-35.
Title:	EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib.
Author:	Corcoran, Ryan B\|Ebi, Hiromichi\|Turke, Alexa B\|Coffee, Erin M\|Nishino, Michiya\|Cogdill, Alexandria P\|Brown, Ronald D\|Della Pelle, Patricia\|Dias-Santagata, Dora\|Hung, Kenneth E\|Flaherty, Keith T\|Piris, Adriano\|Wargo, Jennifer A\|Settleman, Jeffrey\|Mino-Kenu
PMID:	22448344

1291.
Journal:	Med Oncol. 2012 Dec;29(4):2864-5.
Title:	Three different KRAS statuses in three synchronous colorectal cancers.
Author:	Jolissaint, L\|Cacheux, W\|Mariani, P\|Le Tourneau, C\|Lievre, A\|Lappartient, E\|Margogne, A\|Farkhondeh, F\|de Cremoux, P
PMID:	22467075

1292.
Journal:	J Med Chem. 2012 Apr 26;55(8):3725-38.
Title:	Phthalocyanine-peptide conjugates for epidermal growth factor receptor targeting.
Author:	Ongarora, Benson G\|Fontenot, Krystal R\|Hu, Xiaoke\|Sehgal, Inder\|Satyanarayana-Jois, Seetharama D\|Vicente, M Graca H
PMID:	22468711

1293.
Journal:	J Clin Oncol. 2012 May 20;30(15):1735-7.
Title:	Explaining the unexplainable: EGFR antibodies in colorectal cancer.
Author:	Grothey, Axel\|Lenz, Heinz-Josef
PMID:	22473160

1294.
Journal:	Int J Oncol. 2012 Jul;41(1):317-24.
Title:	ErbB3 expression predicts sensitivity to elisidepsin treatment: in vitro synergism with cisplatin, paclitaxel and gemcitabine in lung, breast and colon cancer cell lines.
Author:	Teixido, Cristina\|Arguelaguet, Elisabet\|Pons, Berta\|Aracil, Miguel\|Jimeno, Jose\|Somoza, Rosa\|Mares, Roso\|Ramon Y Cajal, Santiago\|Hernandez-Losa, Javier
PMID:	22485250

1295.
Journal:	Br J Clin Pharmacol. 2012 May;73(5):776-85.
Title:	Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan.
Author:	Etienne-Grimaldi, Marie-Christine\|Bennouna, Jaafar\|Formento, Jean-Louis\|Douillard, Jean-Yves\|Francoual, Mireille\|Hennebelle, Isabelle\|Chatelut, Etienne\|Francois, Eric\|Faroux, Roger\|El Hannani, Chaza\|Jacob, Jacques-Henri\|Milano, Gerard
PMID:	22486600

1296.
Journal:	Neoplasma. 2012;59(4):376-83.
Title:	Mutation pattern of KRAS and BRAF oncogenes in colorectal cancer patients.
Author:	Rako, I\|Jakic-Razumovic, J\|Katalinic, D\|Sertic, J\|Plestina, S
PMID:	22489692

1297.
Journal:	J Transl Med. 2012 Apr 10;10:71.
Title:	Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab.
Author:	Scartozzi, Mario\|Giampieri, Riccardo\|Maccaroni, Elena\|Mandolesi, Alessandra\|Biagetti, Simona\|Alfonsi, Simona\|Giustini, Lucio\|Loretelli, Cristian\|Faloppi, Luca\|Bittoni, Alessandro\|Bianconi, Maristella\|Del Prete, Michela\|Bearzi, Italo\|Cascinu, Stefano
PMID:	22490361

1298.
Journal:	Cell Death Dis. 2012 Apr 12;3:e295.
Title:	Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity.
Author:	Siegemund, M\|Pollak, N\|Seifert, O\|Wahl, K\|Hanak, K\|Vogel, A\|Nussler, A K\|Gottsch, D\|Munkel, S\|Bantel, H\|Kontermann, R E\|Pfizenmaier, K
PMID:	22495350

1299.
Journal:	Neoplasia. 2012 Mar;14(3):190-205.
Title:	Oncogenic KRAS impairs EGFR antibodies' efficiency by C/EBPbeta-dependent suppression of EGFR expression.
Author:	Derer, Stefanie\|Berger, Sven\|Schlaeth, Martin\|Schneider-Merck, Tanja\|Klausz, Katja\|Lohse, Stefan\|Overdijk, Marije B\|Dechant, Michael\|Kellner, Christian\|Nagelmeier, Iris\|Scheel, Andreas H\|Lammerts van Bueren, Jeroen J\|van de Winkel, Jan G J\|Parren, Paul W
PMID:	22496619

1300.
Journal:	Transl Oncol. 2012 Apr;5(2):105-12. Epub 2012 Apr 1.
Title:	hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study.
Author:	Lastraioli, Elena\|Bencini, Lapo\|Bianchini, Elisa\|Romoli, Maria Raffaella\|Crociani, Olivia\|Giommoni, Elisa\|Messerini, Luca\|Gasperoni, Silvia\|Moretti, Renato\|Di Costanzo, Francesco\|Boni, Luca\|Arcangeli, Annarosa
PMID:	22496927

1301.
Journal:	Int J Mol Med. 2012 Jul;30(1):126-32.
Title:	Antitumor effect of FP3 in combination with cetuximab on patient-derived tumor tissue xenograft models of primary colon carcinoma and related lymphatic and hepatic metastases.
Author:	Dong, Xiaofang\|Jin, Ketao\|Hu, Xiaoyan\|Du, Fangmin\|Lan, Huanrong\|Han, Na\|Ma, Zhaosheng\|Xie, Bojian\|Cui, Binbin\|Teng, Lisong\|Cao, Feilin
PMID:	22505231

1302.
Journal:	J BUON. 2012 Jan-Mar;17(1):73-8.
Title:	Meta-analysis of the predictive value of KRAS mutations in treatment response using cetuximab in colorectal cancer.
Author:	Tsoukalas, N\|Tzovaras, A A\|Tolia, M\|Kostakis, I D\|Papakostidi, A\|Pistamaltzian, N\|Ardavanis, A
PMID:	22517696

1303.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G111-9.
Title:	Epidermal growth factor receptor transactivation is required for proteinase-activated receptor-2-induced COX-2 expression in intestinal epithelial cells.
Author:	Hirota, Christina L\|Moreau, France\|Iablokov, Vadim\|Dicay, Michael\|Renaux, Bernard\|Hollenberg, Morley D\|MacNaughton, Wallace K
PMID:	22517768

1304.
Journal:	J Cancer Res Clin Oncol. 2012 Sep;138(9):1487-92.
Title:	Anti-EGFR (cetuximab) combined with irinotecan for treatment of elderly patients with metastatic colorectal cancer (mCRC).
Author:	Abdelwahab, S\|Azmy, A\|Abdel-Aziz, H\|Salim, H\|Mahmoud, A
PMID:	22526166

1305.
Journal:	Br J Cancer. 2012 May 22;106(11):1826-32.
Title:	Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer.
Author:	Pichler, M\|Winter, E\|Stotz, M\|Eberhard, K\|Samonigg, H\|Lax, S\|Hoefler, G
PMID:	22549179

1306.
Journal:	Oncol Rep. 2012 Jul;28(1):15-20.
Title:	Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells.
Author:	Li, Bo\|Gao, Shuohui\|Wei, Feng\|Bellail, Anita C\|Hao, Chunhai\|Liu, Tongjun
PMID:	22552366

1307.
Journal:	Int J Oncol. 2012 Jul;41(1):211-8.
Title:	CD44 enhances the epithelial-mesenchymal transition in association with colon cancer invasion.
Author:	Cho, Sang Hyuk\|Park, Yeon Sun\|Kim, Hun Jin\|Kim, Chang Hyun\|Lim, Sang Woo\|Huh, Jung Wook\|Lee, Jae Hyuk\|Kim, Hyeong Rok
PMID:	22552741

1308.
Journal:	Mol Cancer Ther. 2012 Jul;11(7):1385-8.
Title:	Early FDG/PET scanning as a pharmacodynamic marker of anti-EGFR antibody activity in colorectal cancer.
Author:	Krystal, Geoffrey W\|Alesi, Erin\|Tatum, James L
PMID:	22562987

1309.
Journal:	Curr Pharm Des. 2012;18(20):2901-13.
Title:	Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors in cancer therapy: advances and perspectives.
Author:	Xue, Mengzhu\|Cao, Xianwen\|Zhong, Ye\|Kuang, Dong\|Liu, Xiaofeng\|Zhao, Zhenjiang\|Li, Honglin
PMID:	22571659

1310.
Journal:	J Immunother. 2012 Jun;35(5):367-73.
Title:	Monoclonal antibody therapy of pancreatic cancer with cetuximab: potential for immune modulation.
Author:	Luedke, Eric\|Jaime-Ramirez, Alena Cristina\|Bhave, Neela\|Carson, William E 3rd
PMID:	22576341

1311.
Journal:	Int J Oncol. 2012 Aug;41(2):583-8.
Title:	Differential response to EGFR- and VEGF-targeted therapies in patient-derived tumor tissue xenograft models of colon carcinoma and related metastases.
Author:	Jin, Ketao\|Lan, Huanrong\|Cao, Feilin\|Han, Na\|Xu, Zhenzhen\|Li, Guangliang\|He, Kuifeng\|Teng, Lisong
PMID:	22581265

1312.
Journal:	Oncologist. 2012;17(6):823-9.
Title:	High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease.
Author:	Ruzzo, Annamaria\|Graziano, Francesco\|Vincenzi, Bruno\|Canestrari, Emanuele\|Perrone, Giuseppe\|Galluccio, Nadia\|Catalano, Vincenzo\|Loupakis, Fotios\|Rabitti, Carla\|Santini, Daniele\|Tonini, Giuseppe\|Fiorentini, Giammaria\|Rossi, David\|Falcone, Alfredo\|Magnani,
PMID:	22584434

1313.
Journal:	Am J Clin Pathol. 2012 Jun;137(6):847-59.
Title:	Molecular testing in colorectal cancer: diagnosis of Lynch syndrome and personalized cancer medicine.
Author:	Shi, Chanjuan\|Washington, Kay
PMID:	22586043

1314.
Journal:	Expert Opin Biol Ther. 2012 Jun;12 Suppl 1:S209-15.
Title:	The importance of examining the proportion of circulating DNA originating from tumor, microenvironment and normal cells in colorectal cancer patients.
Author:	Mouliere, Florent\|Thierry, Alain R
PMID:	22594497

1315.
Journal:	Cancer Chemother Pharmacol. 2012 Jun;69(6):1647-55.
Title:	Loss of PTEN expression as a predictor of resistance to anti-EGFR monoclonal therapy in metastatic colorectal cancer: evidence from retrospective studies.
Author:	Wang, Zhen-Hua\|Gao, Qin-Yan\|Fang, Jing-Yuan
PMID:	22610356

1316.
Journal:	Drugs. 2012 May 28;72(8):1057-73.
Title:	The role of capecitabine in locally advanced rectal cancer treatment: an update.
Author:	Fernandez-Martos, Carlos\|Nogue, Miquel\|Cejas, Paloma\|Moreno-Garcia, Victor\|Machancoses, Ana Hernandez\|Feliu, Jaime
PMID:	22621694

1317.
Journal:	Anticancer Res. 2012 Jun;32(6):2315-21.
Title:	Amphiregulin is a prognostic factor in colorectal cancer.
Author:	Ohchi, Takafumi\|Akagi, Yoshito\|Kinugasa, Tetsushi\|Kakuma, Tatsuyuki\|Kawahara, Akihiro\|Sasatomi, Teruo\|Gotanda, Yukito\|Yamaguchi, Keizo\|Tanaka, Natsuki\|Ishibashi, Yoshiaki\|Miyamoto, Shingo\|Kage, Masayoshi\|Shirouzu, Kazuo
PMID:	22641668

1318.
Journal:	Gastroenterology. 2012 Sep;143(3):730-740.
Title:	A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans.
Author:	Bongers, Gerold\|Muniz, Luciana R\|Pacer, Michelle E\|Iuga, Alina C\|Thirunarayanan, Nanthakumar\|Slinger, Erik\|Smit, Martine J\|Reddy, E Premkumar\|Mayer, Lloyd\|Furtado, Glaucia C\|Harpaz, Noam\|Lira, Sergio A
PMID:	22643351

1319.
Journal:	PLoS One. 2012;7(5):e38033.
Title:	KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors.
Author:	Garrido-Laguna, Ignacio\|Hong, David S\|Janku, Filip\|Nguyen, Ly M\|Falchook, Gerald S\|Fu, Siqing\|Wheler, Jenifer J\|Luthra, Rajyalakshmi\|Naing, Aung\|Wang, Xuemei\|Kurzrock, Razelle
PMID:	22675430

1320.
Journal:	Mol Cancer. 2012 Jun 8;11:38.
Title:	Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer.
Author:	Nelson, Laura D\|Bender, Christian\|Mannsperger, Heiko\|Buergy, Daniel\|Kambakamba, Patryk\|Mudduluru, Giridhar\|Korf, Ulrike\|Hughes, Dennis\|Van Dyke, Michael W\|Allgayer, Heike
PMID:	22682314

1321.
Journal:	Oral Oncol. 2012 Oct;48(10):991-6.
Title:	Epidermal growth factor receptor (EGFR) in salivary gland carcinomas: potentials as therapeutic target.
Author:	Clauditz, Till Sebastian\|Gontarewicz, Artur\|Lebok, Patrick\|Tsourlakis, Maria-Christina\|Grob, Tobias J\|Munscher, Adrian\|Sauter, Guido\|Bokemeyer, Carsten\|Knecht, Rainald\|Wilczak, Waldemar
PMID:	22694907

1322.
Journal:	PLoS One. 2012;7(6):e38231.
Title:	Phase I study of cetuximab, irinotecan, and vandetanib (ZD6474) as therapy for patients with previously treated metastastic colorectal cancer.
Author:	Meyerhardt, Jeffrey A\|Ancukiewicz, Marek\|Abrams, Thomas A\|Schrag, Deborah\|Enzinger, Peter C\|Chan, Jennifer A\|Kulke, Matthew H\|Wolpin, Brian M\|Goldstein, Michael\|Blaszkowsky, Lawrence\|Zhu, Andrew X\|Elliott, Meaghan\|Regan, Eileen\|Jain, Rakesh K\|Duda, Dan G
PMID:	22701615

1323.
Journal:	Oncol Rep. 2012 Sep;28(3):855-61.
Title:	Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy.
Author:	Saigusa, Susumu\|Tanaka, Koji\|Toiyama, Yuji\|Matsushita, Kohei\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Hiro, Junichiro\|Inoue, Yasuhiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22711167

1324.
Journal:	Drugs. 2012 Jun 19;72 Suppl 1:28-36.
Title:	Prognostic and predictive value of K-RAS mutations in non-small cell lung cancer.
Author:	Califano, Raffaele\|Landi, Lorenza\|Cappuzzo, Federico
PMID:	22712795

1325.
Journal:	Small GTPases. 2012 Jan-Mar;3(1):34-9.
Title:	KRAS mutant colorectal tumors: past and present.
Author:	Brand, Toni M\|Wheeler, Deric L
PMID:	22714415

1326.
Journal:	Nature. 2012 Jun 28;486(7404):532-6.
Title:	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
Author:	Misale, Sandra\|Yaeger, Rona\|Hobor, Sebastijan\|Scala, Elisa\|Janakiraman, Manickam\|Liska, David\|Valtorta, Emanuele\|Schiavo, Roberta\|Buscarino, Michela\|Siravegna, Giulia\|Bencardino, Katia\|Cercek, Andrea\|Chen, Chin-Tung\|Veronese, Silvio\|Zanon, Carlo\|Sartore-B
PMID:	22722830

1327.
Journal:	Rom J Morphol Embryol. 2012;53(2):277-85.
Title:	Study of molecular prognostic factors Bcl-2 and EGFR in rectal mucinous carcinomas.
Author:	Afrem, Georgeta\|Mogoanta, S S\|Secureanu, F A\|Olaru, A\|Neamtu, Carmen\|Totolici, B D\|Ionila, M\|Craitoiu, Stefania
PMID:	22732796

1328.
Journal:	J Hepatobiliary Pancreat Sci. 2012 Sep;19(5):528-35.
Title:	Selecting the best targeted agent in first-line treatment of unresectable liver metastases from colorectal cancer: does the bench have the answers?
Author:	Benhaim, L\|Loupakis, F\|Labonte, M J\|Lenz, H J
PMID:	22735932

1329.
Journal:	Oncol Lett. 2012 Mar;3(3):649-653.
Title:	Acquired/intratumoral mutation of KRAS during metastatic progression of colorectal carcinogenesis.
Author:	Otsuka, Kazunori\|Satoyoshi, Rika\|Nanjo, Hiroshi\|Miyazawa, Hideaki\|Abe, Yuki\|Tanaka, Masamitsu\|Yamamoto, Yuzo\|Shibata, Hiroyuki
PMID:	22740969

1330.
Journal:	Cancer Res. 2012 Sep 1;72(17):4383-93. Epub 2012 Jul 2.
Title:	Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
Author:	Dulak, Austin M\|Schumacher, Steven E\|van Lieshout, Jasper\|Imamura, Yu\|Fox, Cameron\|Shim, Byoungyong\|Ramos, Alex H\|Saksena, Gordon\|Baca, Sylvan C\|Baselga, Jose\|Tabernero, Josep\|Barretina, Jordi\|Enzinger, Peter C\|Corso, Giovanni\|Roviello, Franco\|Lin, Lin\|Ba
PMID:	22751462

1331.
Journal:	PLoS One. 2012;7(6):e39552.
Title:	Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials.
Author:	Rinella, Erica S\|Threadgill, David W
PMID:	22761823

1332.
Journal:	PLoS One. 2012;7(6):e39682.
Title:	Alteration of EGFR spatiotemporal dynamics suppresses signal transduction.
Author:	Turk, Harmony F\|Barhoumi, Rola\|Chapkin, Robert S
PMID:	22761867

1333.
Journal:	Oncol Rep. 2012 Sep;28(3):889-94.
Title:	Involvement of nuclear NHERF1 in colorectal cancer progression.
Author:	Mangia, Anita\|Saponaro, Concetta\|Malfettone, Andrea\|Bisceglie, Domenico\|Bellizzi, Antonia\|Asselti, Mariaconsilia\|Popescu, Ondina\|Reshkin, Stephan J\|Paradiso, Angelo\|Simone, Giovanni
PMID:	22766563

1334.
Journal:	J Clin Invest. 2012 Aug;122(8):2780-92.
Title:	Epidermal growth factor receptor inhibits colitis-associated cancer in mice.
Author:	Dube, Philip E\|Yan, Fang\|Punit, Shivesh\|Girish, Nandini\|McElroy, Steven J\|Washington, M Kay\|Polk, D Brent
PMID:	22772467

1335.
Journal:	In Vivo. 2012 Jul-Aug;26(4):537-47.
Title:	A comprehensive procedural approach to genotyping KRAS and BRAF from paraffin embedded tissues for diagnostic purposes.
Author:	Palmirotta, Raffaele\|Ludovici, Giorgia\|De Marchis, Maria Laura\|Leone, Barbara\|Formica, Vincenzo\|Ettorre, Giuseppe Maria\|Cavaliere, Francesco\|Della-Morte, David\|Ferroni, Patrizia\|Roselli, Mario\|Guadagni, Fiorella
PMID:	22773565

1336.
Journal:	Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):E2127-33.
Title:	Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
Author:	Ohashi, Kadoaki\|Sequist, Lecia V\|Arcila, Maria E\|Moran, Teresa\|Chmielecki, Juliann\|Lin, Ya-Lun\|Pan, Yumei\|Wang, Lu\|de Stanchina, Elisa\|Shien, Kazuhiko\|Aoe, Keisuke\|Toyooka, Shinichi\|Kiura, Katsuyuki\|Fernandez-Cuesta, Lynnette\|Fidias, Panos\|Yang, James Chi
PMID:	22773810

1337.
Journal:	Oncol Lett. 2012 May;3(5):1129-1135.
Title:	The pattern of epidermal growth factor receptor variation with disease progression and aggressiveness in colorectal cancer depends on tumor location.
Author:	Papagiorgis, Petros C\|Zizi, Adamantia E\|Tseleni, Sophia\|Oikonomakis, Ioannis N\|Nikiteas, Nikolaos I
PMID:	22783405

1338.
Journal:	Clin Lab. 2012;58(5-6):441-8.
Title:	Evaluation of carcinoembryonic antigen (CEA), epidermal growth factor receptor (EGFR), epithelial cell adhesion molecule EpCAM (GA733-2), and carbohydrate antigen 19-9 (CA 19-9) levels in colorectal cancer patients and correlation with clinicopathological
Author:	Mourtzikou, Antonia\|Stamouli, Marilena\|Kroupis, Christos\|Christodoulou, Spyridon\|Skondra, Marika\|Kastania, Anastasia\|Pectasides, Demetrios\|Athanasas, Georgios\|Dimas, Claire
PMID:	22783573

1339.
Journal:	Mol Cancer. 2012 Jul 12;11:45.
Title:	Cisplatin and ultra-violet-C synergistically down-regulate receptor tyrosine kinases in human colorectal cancer cells.
Author:	Kawaguchi, Junji\|Adachi, Seiji\|Yasuda, Ichiro\|Yamauchi, Takahiro\|Nakashima, Masanori\|Ohno, Tomohiko\|Shimizu, Masahito\|Yoshioka, Takashi\|Itani, Masahiko\|Kozawa, Osamu\|Moriwaki, Hisataka
PMID:	22788833

1340.
Journal:	Carcinogenesis. 2012 Oct;33(10):1930-9.
Title:	Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts.
Author:	Mustafi, Reba\|Dougherty, Urszula\|Shah, Hardik\|Dehghan, Hooman\|Gliksberg, Ariel\|Wu, Jiang\|Zhu, Hongyan\|Joseph, Loren\|Hart, John\|Dive, Caroline\|Fichera, Alessandro\|Threadgill, David\|Bissonnette, Marc
PMID:	22791816

1341.
Journal:	Oncol Rep. 2012 Oct;28(4):1187-92.
Title:	KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung.
Author:	Yokota, Keisuke\|Sasaki, Hidefumi\|Okuda, Katsuhiro\|Shimizu, Shigeki\|Shitara, Masayuki\|Hikosaka, Yu\|Moriyama, Satoru\|Yano, Motoki\|Fujii, Yoshitaka
PMID:	22797671

1342.
Journal:	BMC Cancer. 2012 Jul 17;12:292.
Title:	Beyond KRAS mutation status: influence of KRAS copy number status and microRNAs on clinical outcome to cetuximab in metastatic colorectal cancer patients.
Author:	Mekenkamp, Leonie J M\|Tol, Jolien\|Dijkstra, Jeroen R\|de Krijger, Inge\|Vink-Borger, M Elisa\|van Vliet, Shannon\|Teerenstra, Steven\|Kamping, Eveline\|Verwiel, Eugene\|Koopman, Miriam\|Meijer, Gerrit A\|van Krieken, J Han Jm\|Kuiper, Roland\|Punt, Cornelis J A\|Nagt
PMID:	22804917

1343.
Journal:	Br J Cancer. 2012 Aug 7;107(4):626-31.
Title:	KRAS mutation detection by high-resolution melting analysis significantly predicts clinical benefit of cetuximab in metastatic colorectal cancer.
Author:	Malapelle, U\|Carlomagno, C\|Salatiello, M\|De Stefano, A\|De Luca, C\|Bianco, R\|Marciano, R\|Cimminiello, C\|Bellevicine, C\|De Placido, S\|Troncone, G
PMID:	22805329

1344.
Journal:	Virchows Arch. 2012 Sep;461(3):231-43.
Title:	Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer : future possibilities for personalised treatment by use of biomarkers.
Author:	de Cuba, E M V\|Kwakman, R\|van Egmond, M\|Bosch, L J W\|Bonjer, H J\|Meijer, G A\|te Velde, E A
PMID:	22825001

1345.
Journal:	Clin Cancer Res. 2012 Sep 15;18(18):4942-53.
Title:	Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Author:	Prasad, Sahdeo\|Yadav, Vivek R\|Sung, Bokyung\|Reuter, Simone\|Kannappan, Ramaswamy\|Deorukhkar, Amit\|Diagaradjane, Parmeswaran\|Wei, Caimiao\|Baladandayuthapani, Veerabhadran\|Krishnan, Sunil\|Guha, Sushovan\|Aggarwal, Bharat B
PMID:	22832932

1346.
Journal:	Biochem Biophys Res Commun. 2012 Aug 24;425(2):328-32. Epub 2012 Jul 25.
Title:	BDNF/TrkB signaling protects HT-29 human colon cancer cells from EGFR inhibition.
Author:	de Farias, Caroline Brunetto\|Heinen, Tiago Elias\|dos Santos, Rafael Pereira\|Abujamra, Ana Lucia\|Schwartsmann, Gilberto\|Roesler, Rafael
PMID:	22842573

1347.
Journal:	Expert Rev Mol Diagn. 2012 Jul;12(6):593-602.
Title:	Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing.
Author:	Ong, Frank S\|Das, Kingshuk\|Wang, Jay\|Vakil, Hana\|Kuo, Jane Z\|Blackwell, Wendell-Lamar B\|Lim, Stephen W\|Goodarzi, Mark O\|Bernstein, Kenneth E\|Rotter, Jerome I\|Grody, Wayne W
PMID:	22845480

1348.
Journal:	Cytopathology. 2012 Oct;23(5):286-94.
Title:	Molecular diagnosis on tissues and cells: how it affects training and will affect practice in the future.
Author:	Boyd, C\|Boyle, D P
PMID:	22846108

1349.
Journal:	Clin Cancer Res. 2012 Sep 15;18(18):4919-30. Epub 2012 Jul 31.
Title:	The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa.
Author:	Gaedcke, Jochen\|Grade, Marian\|Camps, Jordi\|Sokilde, Rolf\|Kaczkowski, Bogumil\|Schetter, Aaron J\|Difilippantonio, Michael J\|Harris, Curtis C\|Ghadimi, B Michael\|Moller, Soren\|Beissbarth, Tim\|Ried, Thomas\|Litman, Thomas
PMID:	22850566

1350.
Journal:	Clin Transl Oncol. 2012 Oct;14(10):726-39.
Title:	Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM).
Author:	Garcia-Alfonso, Pilar\|Salazar, Ramon\|Garcia-Foncillas, Jesus\|Musulen, Eva\|Garcia-Carbonero, Rocio\|Paya, Artemio\|Perez-Segura, Pedro\|Ramon y Cajal, Santiago\|Navarro, Samuel
PMID:	22855150

1351.
Journal:	PLoS One. 2012;7(7):e42001.
Title:	A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.
Author:	Xie, Tao\|D' Ario, Giovanni\|Lamb, John R\|Martin, Eric\|Wang, Kai\|Tejpar, Sabine\|Delorenzi, Mauro\|Bosman, Fred T\|Roth, Arnaud D\|Yan, Pu\|Bougel, Stephanie\|Di Narzo, Antonio Fabio\|Popovici, Vlad\|Budinska, Eva\|Mao, Mao\|Weinrich, Scott L\|Rejto, Paul A\|Hodgson, J
PMID:	22860045

1352.
Journal:	Pathol Biol (Paris). 2012 Aug;60(4):223-8.
Title:	[Therapeutic monoclonal antibodies in oncology].
Author:	Bouzid, K\|Bedairia, N\|Marty, M
PMID:	22863361

1353.
Journal:	Clin Transl Oncol. 2012 Dec;14(12):937-42.
Title:	Study of KRAS new predictive marker in a clinical laboratory.
Author:	Bando, Inmaculada\|Cillero, Lourdes\|Sanz-Ortega, Julian\|Llovet, Patricia\|Pescador, Paula\|Ferrer, Milagros\|de la Hoya, Miguel\|Sastre, Javier\|Garcia, Eduardo Diaz-Rubio\|Caldes, Trinidad
PMID:	22865324

1354.
Journal:	Mol Cell Biochem. 2012 Nov;370(1-2):191-8.
Title:	EGFR and PKC are involved in the activation of ERK1/2 and p90 RSK and the subsequent proliferation of SNU-407 colon cancer cells by muscarinic acetylcholine receptors.
Author:	Park, Yang-Seo\|Cho, Nam Jeong
PMID:	22865467

1355.
Journal:	Asian Pac J Cancer Prev. 2012;13(5):2235-40.
Title:	c-Src antisense complexed with PAMAM denderimes decreases of c-Src expression and EGFR-dependent downstream genes in the human HT-29 colon cancer cell line.
Author:	Nourazarian, Ali Reza\|Pashaei-Asl, Roghiyeh\|Omidi, Yadollah\|Najar, Ahmad Gholamhoseinian
PMID:	22901200

1356.
Journal:	Gan To Kagaku Ryoho. 2012 Aug;39(8):1221-5.
Title:	[Evaluation of skin toxicity caused by cetuximab related to its clinical response].
Author:	Osuga, Takahiro\|Kogawa, Takahiro\|Kimura, Tomohiro\|Abe, Masakazu\|Tsuji, Yasushi\|Kondo, Hitoshi
PMID:	22902446

1357.
Journal:	Cancer Biol Ther. 2012 Nov;13(13):1235-43.
Title:	K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapy.
Author:	Stec, Rafal\|Bodnar, Lubomir\|Charkiewicz, Radoslaw\|Korniluk, Jan\|Rokita, Marta\|Smoter, Marta\|Ciechowicz, Marzena\|Chyczewski, Lech\|Niklinski, Jacek\|Kozlowski, Wojciech\|Szczylik, Cezary
PMID:	22909976

1358.
Journal:	PLoS One. 2012;7(7):e41347.
Title:	Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations.
Author:	Brandi, Giovanni\|Tavolari, Simona\|De Rosa, Francesco\|Di Girolamo, Stefania\|Agostini, Valentina\|Barbera, Maria Aurelia\|Frega, Giorgio\|Biasco, Guido
PMID:	22911782

1359.
Journal:	Oncol Rep. 2012 Nov;28(5):1579-84.
Title:	The prognostic value of KRAS mutations in patients with colorectal cancer.
Author:	Inoue, Yasuhiro\|Saigusa, Susumu\|Iwata, Takashi\|Okugawa, Yoshinaga\|Toiyama, Yuji\|Tanaka, Koji\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22922794

1360.
Journal:	J Biol Chem. 2012 Oct 12;287(42):35201-11.
Title:	Meprinalpha transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migration.
Author:	Minder, Petra\|Bayha, Elke\|Becker-Pauly, Christoph\|Sterchi, Erwin E
PMID:	22923609

1361.
Journal:	Cell Prolif. 2012 Oct;45(5):413-9.
Title:	EGF signalling pathway regulates colon cancer stem cell proliferation and apoptosis.
Author:	Feng, Y\|Dai, X\|Li, X\|Wang, H\|Liu, J\|Zhang, J\|Du, Y\|Xia, L
PMID:	22925500

1362.
Journal:	Stud Health Technol Inform. 2012;179:143-54.
Title:	Digital pathology in personalized cancer therapy.
Author:	Slodkowska, Janina\|Garcia-Rojo, Marcial
PMID:	22925795

1363.
Journal:	J Transl Med. 2012 Aug 29;10:178.
Title:	Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.
Author:	Palomba, Grazia\|Colombino, Maria\|Contu, Antonio\|Massidda, Bruno\|Baldino, Giovanni\|Pazzola, Antonio\|Ionta, MariaTeresa\|Capelli, Francesca\|Trova, Vittorio\|Sedda, Tito\|Sanna, Giovanni\|Tanda, Francesco\|Budroni, Mario\|Palmieri, Giuseppe\|Cossu, Antonio\|Contu, M
PMID:	22931052

1364.
Journal:	Pathology. 2012 Oct;44(6):547-51.
Title:	The effect of monoclonal antibody cetuximab (C225) in combination with tyrosine kinase inhibitor gefitinib (ZD1839) on colon cancer cell lines.
Author:	Yuan, Heng-Heng\|Han, Yu\|Bian, Wei-xin\|Liu, Lei\|Bai, Yu-xian
PMID:	22935976

1365.
Journal:	Exp Ther Med. 2012 Mar;3(3):547-549.
Title:	Possibility of molecular targeting therapy for the treatment of cancer of unknown primary origin by analysis of intracellular signaling molecules.
Author:	Ohta, Shoichiro\|Cho, Yukiko\|Shibata, Masaharu\|Nagai, Kimihiro\|Iijima, Tatsuo\|Saito, Hitoaki\|Asakura, Hirotaka\|Kojima, Hiroshi
PMID:	22969927

1366.
Journal:	Exp Ther Med. 2012 May;3(5):755-762.
Title:	Combination therapy using oral S-1 and targeted agents against human tumor xenografts in nude mice.
Author:	Nukatsuka, Mamoru\|Saito, Hitoshi\|Nakagawa, Fumio\|Tsujimoto, Hiroaki\|Sakamoto, Kazuki\|Tsukioka, Sayaka\|Uchida, Junji\|Kiniwa, Mamoru\|Kobunai, Takashi\|Takechi, Teiji
PMID:	22969964

1367.
Journal:	Cancer Cell. 2012 Sep 11;22(3):318-30.
Title:	EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Author:	Navas, Carolina\|Hernandez-Porras, Isabel\|Schuhmacher, Alberto J\|Sibilia, Maria\|Guerra, Carmen\|Barbacid, Mariano
PMID:	22975375

1368.
Journal:	Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):e577-84.
Title:	Molecular markers predict distant metastases after adjuvant chemoradiation for rectal cancer.
Author:	Kim, Jun Won\|Kim, Yong Bae\|Choi, Jun Jeong\|Koom, Woong Sub\|Kim, Hoguen\|Kim, Nam-Kyu\|Ahn, Joong Bae\|Lee, Ikjae\|Cho, Jae Ho\|Keum, Ki Chang
PMID:	22981710

1369.
Journal:	Oncotarget. 2012 Sep;3(9):907-8.
Title:	Mutation specific antibodies: tool or dinosaur?
Author:	von Deimling, Andreas\|Sahm, Felix\|Capper, David
PMID:	23006938

1370.
Journal:	Clin Cancer Res. 2012 Dec 1;18(23):6436-45.
Title:	Redirecting gene-modified T cells toward various cancer types using tagged antibodies.
Author:	Tamada, Koji\|Geng, Degui\|Sakoda, Yukimi\|Bansal, Navneeta\|Srivastava, Ratika\|Li, Zhaoyang\|Davila, Eduardo
PMID:	23032741

1371.
Journal:	Curr Med Chem. 2012;19(33):5735-44.
Title:	Signal transduction pathways of the epidermal growth factor receptor in colorectal cancer and their inhibition by small molecules.
Author:	Efferth, T
PMID:	23033949

1372.
Journal:	Tumori. 2012 Jul-Aug;98(4):408-12.
Title:	The management of skin toxicity during cetuximab treatment in advanced colorectal cancer: how much does it cost? A retrospecive economic assessment from a single-center experience.
Author:	Giuliani, Jacopo\|Indelli, Monica\|Marzola, Marina\|Raisi, Elena\|Frassoldati, Antonio
PMID:	23052154

1373.
Journal:	Bioorg Med Chem. 2012 Nov 15;20(22):6724-31.
Title:	Synthesis and evaluation of apoptosis induction of thienopyrimidine compounds on KRAS and BRAF mutated colorectal cancer cell lines.
Author:	Pedeboscq, Stephane\|Gravier, Denis\|Casadebaig, Francoise\|Hou, Genevieve\|Gissot, Arnaud\|Rey, Christophe\|Ichas, Francois\|De Giorgi, Francesca\|Lartigue, Lydia\|Pometan, Jean-Paul
PMID:	23063521

1374.
Journal:	Sci Signal. 2012 Oct 16;5(246):pe46.
Title:	The response of cancers to BRAF inhibition underscores the importance of cancer systems biology.
Author:	Stites, Edward C
PMID:	23074264

1375.
Journal:	Cancer Invest. 2012 Dec;30(10):741-7.
Title:	Concordant KRAS mutations in primary and metastatic colorectal cancer tissue specimens: a meta-analysis and systematic review.
Author:	Han, Cheng-Bo\|Li, Fan\|Ma, Jie-Tao\|Zou, Hua-Wei
PMID:	23075074

1376.
Journal:	Chemother Res Pract. 2012;2012:198197.
Title:	Antiepidermal growth factor receptor monoclonal antibodies: applications in colorectal cancer.
Author:	Azizi, Efat\|Kittai, Adam\|Kozuch, Peter
PMID:	23091721

1377.
Journal:	Chemother Res Pract. 2012;2012:387172.
Title:	Novel drugs targeting the epidermal growth factor receptor and its downstream pathways in the treatment of colorectal cancer: a systematic review.
Author:	Merla, Amartej\|Goel, Sanjay
PMID:	23097702

1378.
Journal:	Asian Pac J Cancer Prev. 2012;13(8):3967-71.
Title:	Multivariate analysis of molecular indicators for postoperative liver metastasis in colorectal cancer cases.
Author:	Qian, Li-Yuan\|Li, Ping\|Li, Xiao-Rong\|Chen, Dao-Jin\|Zhu, Shai-Hong
PMID:	23098501

1379.
Journal:	Dtsch Med Wochenschr. 2012 Nov;137(45):2327-31.
Title:	[The change of pathology in the era of personalized medicine using the example of discordant KRAS mutational status in metastasized colorectal carcinoma].
Author:	Hekeler, E\|Zoller, W G\|Wiedorn, K H\|Bosse, A
PMID:	23111797

1380.
Journal:	Mar Drugs. 2012 Sep;10(9):2055-68.
Title:	In vivo induction of apoptosis by fucoxanthin, a marine carotenoid, associated with down-regulating STAT3/EGFR signaling in sarcoma 180 (S180) xenografts-bearing mice.
Author:	Wang, Jun\|Chen, Shihui\|Xu, Shiqiang\|Yu, Xing\|Ma, Dongqing\|Hu, Xiamin\|Cao, Xiaolu
PMID:	23118721

1381.
Journal:	PLoS One. 2012;7(10):e48461.
Title:	Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis.
Author:	Peng, Zhongsheng\|Raufman, Jean-Pierre\|Xie, Guofeng
PMID:	23119029

1382.
Journal:	Int J Biol Markers. 2012 Dec 27;27(4):e366-74.
Title:	Survey of KRAS, BRAF and PIK3CA mutational status in 209 consecutive Italian colorectal cancer patients.
Author:	Bozzao, Cristina\|Varvara, Dora\|Piglionica, Marilidia\|Bagnulo, Rosanna\|Forte, Giovanna\|Patruno, Margherita\|Russo, Silvana\|Piscitelli, Domenico\|Stella, Alessandro\|Resta, Nicoletta
PMID:	23125007

1383.
Journal:	Clin Res Hepatol Gastroenterol. 2012 Sep;36 Suppl 1:S53-60.
Title:	Chemoprevention of colorectal cancer with ursodeoxycholic acid: pro.
Author:	Serfaty, Lawrence
PMID:	23141895

1384.
Journal:	PLoS One. 2012;7(11):e48803.
Title:	Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.
Author:	Cohen, Gadi\|Lecht, Shimon\|Arien-Zakay, Hadar\|Ettinger, Keren\|Amsalem, Orit\|Oron-Herman, Mor\|Yavin, Eylon\|Prus, Diana\|Benita, Simon\|Nissan, Aviram\|Lazarovici, Philip
PMID:	23144978

1385.
Journal:	Gan To Kagaku Ryoho. 2012 Nov;39(11):1618-25.
Title:	[Predictive biomarkers for anti-EGFR antibodies].
Author:	Bando, Hideaki\|Yoshino, Takayuki
PMID:	23152013

1386.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):590-4.
Title:	[Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma].
Author:	Ling, Yun\|Ying, Jian-ming\|Qiu, Tian\|Shan, Ling\|Guo, Lei\|Lu, Ning
PMID:	23157825

1387.
Journal:	Cell Cycle. 2012 Dec 1;11(23):4447-61.
Title:	Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.
Author:	Chappell, William H\|Abrams, Stephen L\|Franklin, Richard A\|LaHair, Michelle M\|Montalto, Giuseppe\|Cervello, Melchiorre\|Martelli, Alberto M\|Nicoletti, Ferdinando\|Candido, Saverio\|Libra, Massimo\|Polesel, Jerry\|Talamini, Renato\|Milella, Michele\|Tafuri, Agostin
PMID:	23159854

1388.
Journal:	Pol J Pathol. 2012 Nov;63(3):145-64.
Title:	KRAS mutation testing in colorectal cancer as an example of the pathologist's role in personalized targeted therapy: a practical approach.
Author:	Domagala, Pawel\|Hybiak, Jolanta\|Sulzyc-Bielicka, Violetta\|Cybulski, Cezary\|Rys, Janusz\|Domagala, Wenancjusz
PMID:	23161231

1389.
Journal:	Asian Pac J Cancer Prev. 2012;13(9):4751-6.
Title:	Combined EGFR and c-Src antisense oligodeoxynucleotides encapsulated with PAMAM Denderimers inhibit HT-29 colon cancer cell proliferation.
Author:	Nourazarian, Ali Reza\|Najar, Ahmad Gholamhoseinian\|Farajnia, Safar\|Khosroushahi, Ahmad Yari\|Pashaei-Asl, Roghiyeh\|Omidi, Yadollah
PMID:	23167414

1390.
Journal:	J Transl Med. 2012 Nov 21;10:232.
Title:	Fc gamma receptor IIIa polymorphisms in advanced colorectal cancer patients correlated with response to anti-EGFR antibodies and clinical outcome.
Author:	Calemma, Rosa\|Ottaiano, Alessandro\|Trotta, Anna Maria\|Nasti, Guglielmo\|Romano, Carmela\|Napolitano, Maria\|Galati, Domenico\|Borrelli, Pasquale\|Zanotta, Serena\|Cassata, Antonino\|Castello, Giuseppe\|Iaffaioli, Vincenzo Rosario\|Scala, Stefania
PMID:	23171437

1391.
Journal:	Development. 2012 Dec;139(24):4524-35.
Title:	Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut.
Author:	Cordero, Julia B\|Stefanatos, Rhoda K\|Myant, Kevin\|Vidal, Marcos\|Sansom, Owen J
PMID:	23172913

1392.
Journal:	BMC Cancer. 2012 Nov 23;12:548.
Title:	Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancer.
Author:	Kristensen, Lasse Sommer\|Kjeldsen, Tina Ellegaard\|Hager, Henrik\|Hansen, Lise Lotte
PMID:	23173730

1393.
Journal:	Crit Rev Oncog. 2012;17(4):345-59.
Title:	Current status of radiosensitizing agents for the management of rectal cancer.
Author:	Illum, Henrik
PMID:	23176042

1394.
Journal:	Cell. 2012 Nov 21;151(5):937-50.
Title:	MED12 controls the response to multiple cancer drugs through regulation of TGF-beta receptor signaling.
Author:	Huang, Sidong\|Holzel, Michael\|Knijnenburg, Theo\|Schlicker, Andreas\|Roepman, Paul\|McDermott, Ultan\|Garnett, Mathew\|Grernrum, Wipawadee\|Sun, Chong\|Prahallad, Anirudh\|Groenendijk, Floris H\|Mittempergher, Lorenza\|Nijkamp, Wouter\|Neefjes, Jacques\|Salazar, Ramo
PMID:	23178117

1395.
Journal:	Cancer Genet. 2012 Dec;205(12):630-5.
Title:	Epidermal growth factor receptor (EGFR) gene copy number in colorectal adenoma-carcinoma progression.
Author:	Flora, Marcella\|Piana, Simonetta\|Bassano, Cristina\|Bisagni, Alessandra\|De Marco, Loredana\|Ciarrocchi, Alessia\|Tagliavini, Elena\|Gardini, Giorgio\|Tamagnini, Ione\|Banzi, Chiara\|Bisagni, Giancarlo
PMID:	23181982

1396.
Journal:	BMC Cancer. 2012 Nov 30;12:564.
Title:	Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.
Author:	Gandhy, Shruti U\|Kim, Kyounghyun\|Larsen, Lesley\|Rosengren, Rhonda J\|Safe, Stephen
PMID:	23194063

1397.
Journal:	Oncol Lett. 2012 Oct;4(4):705-710.
Title:	KRAS mutations and subtyping in colorectal cancer in Jordanian patients.
Author:	Elbjeirami, Wafa M\|Sughayer, Maher A
PMID:	23205087

1398.
Journal:	Acta Cytol. 2012;56(6):655-60.
Title:	Circulating tumor cells in lung cancer.
Author:	Young, Rachel\|Pailler, Emma\|Billiot, Fanny\|Drusch, Francoise\|Barthelemy, Amelie\|Oulhen, Marianne\|Besse, Benjamin\|Soria, Jean-Charles\|Farace, Francoise\|Vielh, Philippe
PMID:	23207444

1399.
Journal:	Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21046-51.
Title:	Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.
Author:	Ashraf, Shazad Q\|Nicholls, Angela M\|Wilding, Jennifer L\|Ntouroupi, Triantafyllia G\|Mortensen, Neil J\|Bodmer, Walter F
PMID:	23213241

1400.
Journal:	Cancer Biomark. 2012;11(5):219-26.
Title:	Expression of EGFR, Her2 predict lymph node metastasis (LNM)-associated metastasis in colorectal cancer.
Author:	Lu, Yuanming\|Jingyan, Gao\|Baorong, Song\|Peng, Junjie\|Xu, Ye\|Cai, Sanjun
PMID:	23220854

1401.
Journal:	PLoS One. 2012;7(11):e50806.
Title:	Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer.
Author:	Ree, Anne Hansen\|Kristensen, Annette Torgunrud\|Saelen, Marie Gron\|de Wijn, Rik\|Edvardsen, Hege\|Jovanovic, Jovana\|Abrahamsen, Torveig Weum\|Dueland, Svein\|Flatmark, Kjersti
PMID:	23226389

1402.
Journal:	PLoS One. 2012;7(11):e50925.
Title:	No survival benefit from adding cetuximab or panitumumab to oxaliplatin-based chemotherapy in the first-line treatment of metastatic colorectal cancer in KRAS wild type patients: a meta-analysis.
Author:	Zhou, Si-wei\|Huang, Yuan-yuan\|Wei, Ying\|Jiang, Zhi-min\|Zhang, Yuan-dong\|Yang, Qiong\|Xie, De-rong
PMID:	23226426

1403.
Journal:	Exp Ther Med. 2012 Nov;4(5):790-794.
Title:	Detecting KRAS mutations in peripheral blood of colorectal cancer patients by peptide nucleic acid clamp PCR.
Author:	Miyano, Shozo\|Hanazawa, Kisaburo\|Kitabatake, Toshiaki\|Fujisawa, Minoru\|Kojima, Kuniaki
PMID:	23226727

1404.
Journal:	Nihon Rinsho. 2012 Dec;70(12):2152-8.
Title:	[Anti-EGFR antibody therapy for colorectal cancer].
Author:	Ishikawa, Toshiaki\|Uetake, Hiroyuki\|Sugihara, Kenichi
PMID:	23259389

1405.
Journal:	BMC Cancer. 2012 Dec 21;12:612.
Title:	Alternative dosing of dual PI3K and MEK inhibition in cancer therapy.
Author:	Jokinen, Elina\|Laurila, Niina\|Koivunen, Jussi P
PMID:	23259591

1406.
Journal:	Genes Cancer. 2012 Jul;3(7-8):459-66.
Title:	KRAS Testing: A Tool for the Implementation of Personalized Medicine.
Author:	Shackelford, Rodney E\|Whitling, Nicholas A\|McNab, Patricia\|Japa, Shanker\|Coppola, Domenico
PMID:	23264846

1407.
Journal:	Chin J Physiol. 2012 Oct 31;55(5):352-60.
Title:	Discordance between EGFR expression and clinicopathologic parameters of colorectal adenocarcinoma in Taiwan.
Author:	Tsai, Wen-Chiuan\|Lin, Chih-Kung\|Lee, Herng-Sheng\|Chen, Ann\|Nieh, Shin\|Yu, Cheng-Ping\|Wu, Chang-Chieh\|Jao, Shu-Wen\|Jin, Jong-Shiaw
PMID:	23282210

1408.
Journal:	PLoS One. 2012;7(12):e52711.
Title:	Regulation of amphiregulin gene expression by beta-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system.
Author:	Latasa, Maria U\|Salis, Fabiana\|Urtasun, Raquel\|Garcia-Irigoyen, Oihane\|Elizalde, Maria\|Uriarte, Iker\|Santamaria, Monica\|Feo, Francesco\|Pascale, Rosa M\|Prieto, Jesus\|Berasain, Carmen\|Avila, Matias A
PMID:	23285165

1409.
Journal:	Front Immunol. 2013 Jan 7;3:409.
Title:	Prediction of response to anti-EGFR antibodies in metastatic colorectal cancer: looking beyond EGFR inhibition.
Author:	Ottaiano, Alessandro\|Capuozzo, Maurizio\|Nasti, Guglielmo\|Maiolino, Piera\|De Angelis, Valentina\|Scala, Stefania\|Iaffaioli, Rosario V
PMID:	23316197

1410.
Journal:	Asian Pac J Cancer Prev. 2012;13(11):5599-603.
Title:	Mutational analysis of key EGFR pathway genes in Chinese breast cancer patients.
Author:	Tong, Lin\|Yang, Xue-Xi\|Liu, Min-Feng\|Yao, Guang-Yu\|Dong, Jian-Yu\|Ye, Chang-Sheng\|Li, Ming
PMID:	23317280

1411.
Journal:	Front Genet. 2013 Jan 17;3:312.
Title:	High-resolution melting analysis of the common c.1905+1G>A mutation causing dihydropyrimidine dehydrogenase deficiency and lethal 5-fluorouracil toxicity.
Author:	Borras, Emma\|Dotor, Emma\|Arcusa, Angels\|Gamundi, Maria J\|Hernan, Imma\|de Sousa Dias, Miguel\|Mane, Begona\|Agundez, Jose A G\|Blanca, Miguel\|Carballo, Miguel
PMID:	23335937

1412.
Journal:	J Res Med Sci. 2012 Aug;17(8):741-4.
Title:	An immunohistochemical study of EGFR expression in colorectal cancer and its correlation with lymph nodes status and tumor grade.
Author:	Mokhtari, Mojgan\|Ardestani, Mina Memar\|Movahedipour, Mohammad
PMID:	23798940

1413.
Journal:	ISRN Mol Biol. 2012 Jan 31;2012:706545.
Title:	Increased Phospho-Keratin 8 Isoforms in Colorectal Tumors Associated with EGFR Pathway Activation and Reduced Apoptosis.
Author:	Arentz, Georgia\|Chataway, Tim\|Condina, Mark R\|Price, Timothy J\|Hoffmann, Peter\|Hardingham, Jennifer E
PMID:	27398237

1414.
Journal:	ISRN Mol Biol. 2012 May 14;2012:837306.
Title:	K-Ras Mutations in Non-Small-Cell Lung Cancer: Prognostic and Predictive Value.
Author:	D'Arcangelo, Manolo\|Cappuzzo, Federico
PMID:	27398239

1415.
Journal:	J Eur Acad Dermatol Venereol. 2013 Apr;27(4):514-9.
Title:	Phytomenadione pre-treatment in EGFR inhibitor-induced folliculitis.
Author:	Tomkova, H\|Pospiskova, M\|Zabojnikova, M\|Kohoutek, M\|Serclova, M\|Gharibyar, M\|Sternbersky, J
PMID:	22035385

1416.
Journal:	Int J Clin Oncol. 2013 Jun;18(3):454-63.
Title:	Clinical significance of KRAS gene mutation and epidermal growth factor receptor expression in Japanese patients with squamous cell carcinoma of the larynx, oropharynx and hypopharynx.
Author:	Fujii, Satoshi\|Uryu, Hideoki\|Akashi, Ken\|Suzuki, Kensuke\|Yamazaki, Manabu\|Tahara, Makoto\|Hayashi, Ryuichi\|Ochiai, Atsushi
PMID:	22441881

1417.
Journal:	Int J Clin Oncol. 2013 Aug;18(4):670-7.
Title:	Clinical usefulness of KRAS, BRAF, and PIK3CA mutations as predictive markers of cetuximab efficacy in irinotecan- and oxaliplatin-refractory Japanese patients with metastatic colorectal cancer.
Author:	Soeda, Hiroshi\|Shimodaira, Hideki\|Watanabe, Mika\|Suzuki, Takao\|Gamoh, Makio\|Mori, Takahiro\|Komine, Keigo\|Iwama, Noriyuki\|Kato, Shunsuke\|Ishioka, Chikashi
PMID:	22638623

1418.
Journal:	Int J Cancer. 2013 Jan 1;132(1):236-45.
Title:	Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO CRC Stu
Author:	Stintzing, Sebastian\|Kapaun, Christine\|Laubender, Rudiger Paul\|Jung, Andreas\|Neumann, Jens\|Modest, Dominik Paul\|Giessen, Clemens\|Moosmann, Nicolas\|Wollenberg, Andreas\|Kirchner, Thomas\|Heinemann, Volker
PMID:	22644776

1419.
Journal:	Crit Rev Oncol Hematol. 2013 Jan;85(1):45-81.
Title:	Prognostic and predictive biomarkers for epidermal growth factor receptor-targeted therapy in colorectal cancer: beyond KRAS mutations.
Author:	Custodio, Ana\|Feliu, Jaime
PMID:	22647972

1420.
Journal:	Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):201-7.
Title:	KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials.
Author:	Kim, Sun Young\|Shim, Eun Kyung\|Yeo, Hyun Yang\|Baek, Ji Yeon\|Hong, Yong Sang\|Kim, Dae Yong\|Kim, Tae Won\|Kim, Jee Hyun\|Im, Seock-Ah\|Jung, Kyung Hae\|Chang, Hee Jin
PMID:	22672749

1421.
Journal:	Int J Colorectal Dis. 2013 Jan;28(1):9-18.
Title:	FAK, CD44v6, c-Met and EGFR in colorectal cancer parameters: tumour progression, metastasis, patient survival and receptor crosstalk.
Author:	Garouniatis, Alexandros\|Zizi-Sermpetzoglou, Adamantia\|Rizos, Spyros\|Kostakis, Alkiviadis\|Nikiteas, Nikolaos\|Papavassiliou, Athanasios G
PMID:	22733437

1422.
Journal:	Int J Colorectal Dis. 2013 May;28(5):733-4.
Title:	Letter to the editor: Worse prognosis caused by anti-EGFR treatment in advanced colorectal cancer patients with KRAS mutation.
Author:	Yin, Peihao\|Qiu, Yanyan\|Li, Qi
PMID:	22752244

1423.
Journal:	Crit Rev Oncol Hematol. 2013 Feb;85(2):121-35.
Title:	Overview of biomarkers in metastatic colorectal cancer: tumour, blood and patient-related factors.
Author:	Clarke, Stephen J\|Karapetis, Christos S\|Gibbs, Peter\|Pavlakis, Nick\|Desai, Jayesh\|Michael, Michael\|Tebbutt, Niall C\|Price, Tim J\|Tabernero, Josep
PMID:	22762963

1424.
Journal:	Oncogene. 2013 Jun 6;32(23):2873-81.
Title:	Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockade.
Author:	Kasper, S\|Breitenbuecher, F\|Reis, H\|Brandau, S\|Worm, K\|Kohler, J\|Paul, A\|Trarbach, T\|Schmid, K W\|Schuler, M
PMID:	22797062

1425.
Journal:	Gut. 2013 Apr;62(4):540-9.
Title:	A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation improves colorectal cancer classification and cetuximab treatment prediction.
Author:	Tian, Sun\|Simon, Iris\|Moreno, Victor\|Roepman, Paul\|Tabernero, Josep\|Snel, Mireille\|van't Veer, Laura\|Salazar, Ramon\|Bernards, Rene\|Capella, Gabriel
PMID:	22798500

1426.
Journal:	Diagn Cytopathol. 2013 Jul;41(7):595-8.
Title:	Epidermal growth factor receptor and Kras gene expression: reliability of mutational analysis on cytological samples.
Author:	Bozzetti, Cecilia\|Negri, Francesca V\|Azzoni, Cinzia\|Naldi, Nadia\|Nizzoli, Rita\|Bortesi, Beatrice\|Zobbi, Valentina\|Bottarelli, Lorena\|Tiseo, Marcello\|Silini, Enrico Maria\|Ardizzoni, Andrea
PMID:	22833420

1427.
Journal:	Cell Res. 2013 Jan;23(1):13-4.
Title:	Resistance to EGFR blockade in colorectal cancer: liquid biopsies and latent subclones.
Author:	Konieczkowski, David J\|Garraway, Levi A
PMID:	22847744

1428.
Journal:	Oncogene. 2013 Jun 27;32(26):3139-46.
Title:	Aneuploid human colonic epithelial cells are sensitive to AICAR-induced growth inhibition through EGFR degradation.
Author:	Ly, P\|Kim, S B\|Kaisani, A A\|Marian, G\|Wright, W E\|Shay, J W
PMID:	22890317

1429.
Journal:	Int J Cancer. 2013 Apr 1;132(7):1719-20.
Title:	Author's reply to: "Prognostic value of cetuximab related skintoxicity in metastatic colorectal cancer patients and its correlation with parameters of the EGFR signal transduction pathway: results from a randomized trial of the GERMAN AIO CRC Study Group"
Author:	Stintzing, Sebastian\|Heinemann, Volker
PMID:	22930449

1430.
Journal:	Invest New Drugs. 2013 Jun;31(3):516-24.
Title:	Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.
Author:	Gialeli, Ch\|Theocharis, A D\|Kletsas, D\|Tzanakakis, G N\|Karamanos, N K
PMID:	22956286

1431.
Journal:	Curr Pharm Des. 2013;19(5):958-64.
Title:	Irinotecan resistance is accompanied by upregulation of EGFR and Src signaling in human cancer models.
Author:	Petitprez, Amelie\|Larsen, Annette K
PMID:	22973964

1432.
Journal:	J Cell Biochem. 2013 Mar;114(3):514-24.
Title:	Molecular diagnostics and personalized medicine in oncology: challenges and opportunities.
Author:	Normanno, Nicola\|Rachiglio, Anna Maria\|Roma, Cristin\|Fenizia, Francesca\|Esposito, Claudia\|Pasquale, Raffaella\|La Porta, Maria Libera\|Iannaccone, Alessia\|Micheli, Filippo\|Santangelo, Michele\|Bergantino, Francesca\|Costantini, Susan\|De Luca, Antonella
PMID:	22991232

1433.
Journal:	Cancer Lett. 2013 Jan 1;328(1):73-82.
Title:	Celecoxib induces proliferation and Amphiregulin production in colon subepithelial myofibroblasts, activating erk1-2 signaling in synergy with EGFR.
Author:	Benelli, Roberto\|Vene, Roberta\|Minghelli, Simona\|Carlone, Sebastiano\|Gatteschi, Beatrice\|Ferrari, Nicoletta
PMID:	23010081

1434.
Journal:	J Cancer Res Clin Oncol. 2013 Feb;139(2):201-9.
Title:	KRAS p.G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines.
Author:	Messner, Isabelle\|Cadeddu, Giuseppe\|Huckenbeck, Wolfgang\|Knowles, Helen J\|Gabbert, Helmut E\|Baldus, Stephan E\|Schaefer, Karl-Ludwig
PMID:	23015072

1435.
Journal:	Clin Exp Metastasis. 2013 Mar;30(3):309-16.
Title:	Protein pathway activation mapping of colorectal metastatic progression reveals metastasis-specific network alterations.
Author:	Silvestri, Alessandra\|Calvert, Valerie\|Belluco, Claudio\|Lipsky, Michael\|De Maria, Ruggero\|Deng, Jianghong\|Colombatti, Alfonso\|De Marchi, Francesco\|Nitti, Donato\|Mammano, Enzo\|Liotta, Lance\|Petricoin, Emanuel\|Pierobon, Mariaelena
PMID:	23053743

1436.
Journal:	Int J Cancer. 2013 May 1;132(9):2118-26.
Title:	RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma.
Author:	Tennstedt, Pierre\|Fresow, Robert\|Simon, Ronald\|Marx, Andreas\|Terracciano, Luigi\|Petersen, Cordula\|Sauter, Guido\|Dikomey, Ekkehard\|Borgmann, Kerstin
PMID:	23065657

1437.
Journal:	Clin Colorectal Cancer. 2013 Mar;12(1):28-36.
Title:	Impact of STAT3 phosphorylation on the clinical effectiveness of anti-EGFR-based therapy in patients with metastatic colorectal cancer.
Author:	Dobi, Erion\|Monnien, Franck\|Kim, Stefano\|Ivanaj, Arben\|N'Guyen, Thiery\|Demarchi, Martin\|Adotevi, Olivier\|Thierry-Vuillemin, Antoine\|Jary, Marie\|Kantelip, Bernadette\|Pivot, Xavier\|Godet, Yann\|Degano, Severine Valmary\|Borg, Christophe
PMID:	23083634

1438.
Journal:	Eur J Cancer. 2013 Mar;49(5):1117-26.
Title:	UbcH10 overexpression in human lung carcinomas and its correlation with EGFR and p53 mutational status.
Author:	Pallante, Pierlorenzo\|Malapelle, Umberto\|Berlingieri, Maria Teresa\|Bellevicine, Claudio\|Sepe, Romina\|Federico, Antonella\|Rocco, Danilo\|Galgani, Mario\|Chiariotti, Lorenzo\|Sanchez-Cespedes, Montserrat\|Fusco, Alfredo\|Troncone, Giancarlo
PMID:	23102841

1439.
Journal:	Dig Dis Sci. 2013 Apr;58(4):998-1003.
Title:	The usability of allele-specific PCR and reverse-hybridization assays for KRAS genotyping in Serbian colorectal cancer patients.
Author:	Brotto, Ksenija\|Malisic, Emina\|Cavic, Milena\|Krivokuca, Ana\|Jankovic, Radmila
PMID:	23108567

1440.
Journal:	Oncology. 2013;84(2):81-91.
Title:	Relationship between the expression of the extracellular matrix genes SPARC, SPP1, FN1, ITGA5 and ITGAV and clinicopathological parameters of tumor progression and colorectal cancer dissemination.
Author:	Viana, Luciano de Souza\|Affonso, Renato Jose Jr\|Silva, Sandra Regina Morini\|Denadai, Marcos Vinicius Araujo\|Matos, Delcio\|Salinas de Souza, Carolina\|Waisberg, Jaques
PMID:	23128103

1441.
Journal:	Clin Chem. 2013 Jan;59(1):252-60.
Title:	Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.
Author:	Gasch, Christin\|Bauernhofer, Thomas\|Pichler, Martin\|Langer-Freitag, Sabine\|Reeh, Matthias\|Seifert, Adrian M\|Mauermann, Oliver\|Izbicki, Jakob R\|Pantel, Klaus\|Riethdorf, Sabine
PMID:	23136247

1442.
Journal:	Cancer Epidemiol Biomarkers Prev. 2013 Jan;22(1):91-101.
Title:	KRAS testing and epidermal growth factor receptor inhibitor treatment for colorectal cancer in community settings.
Author:	Webster, Jennifer\|Kauffman, Tia L\|Feigelson, Heather Spencer\|Pawloski, Pamala A\|Onitilo, Adedayo A\|Potosky, Arnold L\|Cross, Deanna\|Meier, Paul R\|Mirabedi, Anousheh S\|Delate, Thomas\|Daida, Yihe\|Williams, Andrew E\|Alexander, Gwen L\|McCarty, Catherine A\|Hond
PMID:	23155138

1443.
Journal:	Hum Pathol. 2013 May;44(5):829-36.
Title:	Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome.
Author:	Bettstetter, Marcus\|Berezowska, Sabina\|Keller, Gisela\|Walch, Axel\|Feuchtinger, Annette\|Slotta-Huspenina, Julia\|Feith, Marcus\|Drecoll, Enken\|Hofler, Heinz\|Langer, Rupert
PMID:	23158210

1444.
Journal:	Mol Cell Proteomics. 2013 Feb;12(2):343-55.
Title:	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Author:	Demory Beckler, Michelle\|Higginbotham, James N\|Franklin, Jeffrey L\|Ham, Amy-Joan\|Halvey, Patrick J\|Imasuen, Imade E\|Whitwell, Corbin\|Li, Ming\|Liebler, Daniel C\|Coffey, Robert J
PMID:	23161513

1445.
Journal:	Clin Cancer Res. 2013 Jan 1;19(1):138-47.
Title:	Sphingosine kinase 1 overexpression contributes to cetuximab resistance in human colorectal cancer models.
Author:	Rosa, Roberta\|Marciano, Roberta\|Malapelle, Umberto\|Formisano, Luigi\|Nappi, Lucia\|D'Amato, Claudia\|D'Amato, Valentina\|Damiano, Vincenzo\|Marfe, Gabriella\|Del Vecchio, Silvana\|Zannetti, Antonella\|Greco, Adelaide\|De Stefano, Alfonso\|Carlomagno, Chiara\|Venezia
PMID:	23166225

1446.
Journal:	J Biol Chem. 2013 Jan 25;288(4):2403-13.
Title:	Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines.
Author:	Vartanian, Steffan\|Bentley, Carolyn\|Brauer, Matthew J\|Li, Li\|Shirasawa, Senji\|Sasazuki, Takehiko\|Kim, Jung-Sik\|Haverty, Pete\|Stawiski, Eric\|Modrusan, Zora\|Waldman, Todd\|Stokoe, David
PMID:	23188824

1447.
Journal:	Cancer Lett. 2013 Apr 28;330(2):200-7.
Title:	In vivo molecular imaging of epidermal growth factor receptor in patients with colorectal neoplasia using confocal laser endomicroscopy.
Author:	Liu, Jun\|Zuo, Xiuli\|Li, Changqing\|Yu, Tao\|Gu, Xiaomeng\|Zhou, Chengjun\|Li, Zhen\|Goetz, Martin\|Kiesslich, Ralf\|Li, Yanqing
PMID:	23220286

1448.
Journal:	J Natl Cancer Inst. 2013 Feb 20;105(4):266-73.
Title:	HER3 overexpression and survival in solid tumors: a meta-analysis.
Author:	Ocana, Alberto\|Vera-Badillo, Francisco\|Seruga, Bostjan\|Templeton, Arnoud\|Pandiella, Atanasio\|Amir, Eitan
PMID:	23221996

1449.
Journal:	Int J Clin Exp Pathol. 2013;6(1):24-30. Epub 2012 Nov 20.
Title:	High-sensitivity epidermal growth factor receptor immunostaining for colorectal carcinomas, compared with EGFR PharmDx: a study of diagnostic accuracy.
Author:	Shiogama, Kazuya\|Wongsiri, Trai\|Mizutani, Yasuyoshi\|Inada, Ken-ichi\|Tsutsumi, Yutaka
PMID:	23236539

1450.
Journal:	Clin Cancer Res. 2013 Feb 1;19(3):657-67.
Title:	Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Author:	Mao, Muling\|Tian, Feng\|Mariadason, John M\|Tsao, Chun C\|Lemos, Robert Jr\|Dayyani, Farshid\|Gopal, Y N Vashisht\|Jiang, Zhi-Qin\|Wistuba, Ignacio I\|Tang, Xi M\|Bornman, William G\|Bollag, Gideon\|Mills, Gordon B\|Powis, Garth\|Desai, Jayesh\|Gallick, Gary E\|Davies,
PMID:	23251002

1451.
Journal:	Oncol Lett. 2013 Jan;5(1):249-254.
Title:	Comparison of KRAS/BRAF mutations between primary tumors and serum in colorectal cancer: Biological and clinical implications.
Author:	Pu, Xingxiang\|Pan, Zhizhong\|Huang, Ying\|Tian, Ying\|Guo, Hongqiang\|Wu, Lin\|He, Xuexing\|Chen, Xinggui\|Zhang, Shaodan\|Lin, Tongyu
PMID:	23255930

1452.
Journal:	Eur J Cancer. 2013 Apr;49(6):1161-8.
Title:	Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: analysis of data from the EXTREME and CRYSTAL studies.
Author:	Licitra, Lisa\|Storkel, Stephan\|Kerr, Keith M\|Van Cutsem, Eric\|Pirker, Robert\|Hirsch, Fred R\|Vermorken, Jan B\|von Heydebreck, Anja\|Esser, Regina\|Celik, Ilhan\|Ciardiello, Fortunato
PMID:	23265711

1453.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S485-91.
Title:	KRAS and BRAF mutations in 203 esophageal squamous cell carcinomas: pyrosequencing technology and literature review.
Author:	Shigaki, Hironobu\|Baba, Yoshifumi\|Watanabe, Masayuki\|Miyake, Keisuke\|Murata, Asuka\|Iwagami, Shiro\|Ishimoto, Takatsugu\|Iwatsuki, Masaaki\|Yoshida, Naoya\|Baba, Hideo
PMID:	23274581

1454.
Journal:	Front Biosci (Landmark Ed). 2013 Jan 1;18:394-421.
Title:	Prognostic significance and targeting of HER family in colorectal cancer.
Author:	Khelwatty, Said Abdullah\|Essapen, Sharadah\|Seddon, Alan Michael\|Modjtahedi, Helmout
PMID:	23276932

1455.
Journal:	Front Biosci (Elite Ed). 2013 Jan 1;5:574-82.
Title:	Effect of genomic instability and mutations on the signaling pathways in colon cancer cells.
Author:	Cui, Miao\|Ye, Fei\|Jiang, Bo\|Deng, Peng\|Wang, Xinying\|Jiang, Yong\|Zhang, David Yong
PMID:	23277013

1456.
Journal:	Proteomics. 2013 Mar;13(5):866-77.
Title:	Increased anaerobic metabolism is a distinctive signature in a colorectal cancer cellular model of resistance to antiepidermal growth factor receptor antibody.
Author:	Monteleone, Francesca\|Rosa, Roberta\|Vitale, Monica\|D'Ambrosio, Chiara\|Succoio, Mariangela\|Formisano, Luigi\|Nappi, Lucia\|Romano, Maria Fiammetta\|Scaloni, Andrea\|Tortora, Giampaolo\|Bianco, Roberto\|Zambrano, Nicola
PMID:	23281225

1457.
Journal:	Expert Opin Biol Ther. 2013 Feb;13(2):241-55.
Title:	Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR antibodies: overcoming the mechanisms of cancer cell resistance.
Author:	Troiani, Teresa\|Zappavigna, Silvia\|Martinelli, Erika\|Addeo, Santolo R\|Stiuso, Paola\|Ciardiello, Fortunato\|Caraglia, Michele
PMID:	23281932

1458.
Journal:	HPB (Oxford). 2013 Feb;15(2):106-15.
Title:	Systemic cytotoxic and biological therapies of colorectal liver metastases: expert consensus statement.
Author:	Schwarz, Roderich E\|Berlin, Jordan D\|Lenz, Heinz J\|Nordlinger, Bernard\|Rubbia-Brandt, Laura\|Choti, Michael A
PMID:	23297721

1459.
Journal:	Cancer. 2013 May 1;119(9):1752-60.
Title:	Cohypermethylation of p14 in combination with CADM1 or DCC as a recurrence-related prognostic indicator in stage I esophageal squamous cell carcinoma.
Author:	Lee, Eunju\|Lee, Bo Bin\|Ko, Eunkyung\|Kim, Yujin\|Han, Jungho\|Shim, Young Mog\|Park, Joobae\|Kim, Duk-Hwan
PMID:	23310950

1460.
Journal:	Expert Opin Investig Drugs. 2013 Mar;22(3):341-56.
Title:	Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers.
Author:	Desai, Monica Dandona\|Saroya, Bikramajit Singh\|Lockhart, Albert Craig
PMID:	23316969

1461.
Journal:	Br J Cancer. 2013 Feb 19;108(3):662-7.
Title:	Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting.
Author:	Tiernan, J P\|Perry, S L\|Verghese, E T\|West, N P\|Yeluri, S\|Jayne, D G\|Hughes, T A
PMID:	23322207

1462.
Journal:	J Thorac Oncol. 2013 Feb;8(2):131-9.
Title:	Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation.
Author:	Endo, Hiroko\|Okami, Jiro\|Okuyama, Hiroaki\|Kumagai, Toru\|Uchida, Junji\|Kondo, Jumpei\|Takehara, Tetsuo\|Nishizawa, Yasuko\|Imamura, Fumio\|Higashiyama, Masahiko\|Inoue, Masahiro
PMID:	23328545

1463.
Journal:	Int J Cancer. 2013 Jul 15;133(2):307-14.
Title:	Bevacizumab reduces tumor targeting of antiepidermal growth factor and anti-insulin-like growth factor 1 receptor antibodies.
Author:	Heskamp, Sandra\|Boerman, Otto C\|Molkenboer-Kuenen, Janneke D M\|Oyen, Wim J G\|van der Graaf, Winette T A\|van Laarhoven, Hanneke W M
PMID:	23335047

1464.
Journal:	Histol Histopathol. 2013 Mar;28(3):311-20.
Title:	Chromosome 16q loss--a genetic key to the understanding of breast carcinogenesis.
Author:	Burger, Horst\|de Boer, Mirthe\|van Diest, Paul J\|Korsching, Eberhard
PMID:	23348384

1465.
Journal:	PLoS One. 2013;8(1):e54510.
Title:	Detection of low-abundance KRAS mutations in colorectal cancer using microfluidic capillary electrophoresis-based restriction fragment length polymorphism method with optimized assay conditions.
Author:	Zhang, Huidan\|Song, Jin\|Ren, Hui\|Xu, Zhangrun\|Wang, Xiaonan\|Shan, Lianfeng\|Fang, Jin
PMID:	23355875

1466.
Journal:	EPMA J. 2013 Jan 28;4(1):3.
Title:	Targeted therapies in colorectal cancer-an integrative view by PPPM.
Author:	Hagan, Suzanne\|Orr, Maria C M\|Doyle, Brendan
PMID:	23356214

1467.
Journal:	Nucl Med Biol. 2013 Apr;40(3):424-9.
Title:	Synthesis and application of a novel cysteine-based DTPA-NCS for targeted radioimmunotherapy.
Author:	Lee, So-Young\|Hong, Young Don\|Kim, Hak-Sung\|Choi, Sun-Ju
PMID:	23357082

1468.
Journal:	Arch Pathol Lab Med. 2013 Feb;137(2):155.
Title:	Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma.
Author:	Idowu, Michael O
PMID:	23368856

1469.
Journal:	BMC Cancer. 2013 Feb 2;13:49.
Title:	Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes.
Author:	Pentheroudakis, George\|Kotoula, Vassiliki\|De Roock, Wendy\|Kouvatseas, George\|Papakostas, Pavlos\|Makatsoris, Thomas\|Papamichael, Demetris\|Xanthakis, Ioannis\|Sgouros, Joseph\|Televantou, Despina\|Kafiri, Georgia\|Tsamandas, Athanassios C\|Razis, Evangelia\|Galan
PMID:	23374602

1470.
Journal:	Genet Test Mol Biomarkers. 2013 Apr;17(4):348-51.
Title:	High expression of epidermal growth factor receptor might predict poor survival in patients with colon cancer: a meta-analysis.
Author:	Hong, Liu\|Han, Yu\|Zhang, Hongwei\|Zhao, Qingchuan\|Yang, Jianjun\|Ahuja, Nita
PMID:	23387315

1471.
Journal:	Virchows Arch. 2013 Mar;462(3):329-35.
Title:	Comparison of COBAS 4800 KRAS, TaqMan PCR and high resolution melting PCR assays for the detection of KRAS somatic mutations in formalin-fixed paraffin embedded colorectal carcinomas.
Author:	Harle, Alexandre\|Busser, Benoit\|Rouyer, Marie\|Harter, Valentin\|Genin, Pascal\|Leroux, Agnes\|Merlin, Jean-Louis
PMID:	23400679

1472.
Journal:	Int J Cancer. 2013 Sep 1;133(5):1259-65.
Title:	KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
Author:	Valtorta, Emanuele\|Misale, Sandra\|Sartore-Bianchi, Andrea\|Nagtegaal, Iris D\|Paraf, Francois\|Lauricella, Calogero\|Dimartino, Valentina\|Hobor, Sebastijan\|Jacobs, Bart\|Ercolani, Cristiana\|Lamba, Simona\|Scala, Elisa\|Veronese, Silvio\|Laurent-Puig, Pierre\|Siena
PMID:	23404247

1473.
Journal:	Expert Opin Pharmacother. 2013 Mar;14(4):505-13.
Title:	Everolimus in colorectal cancer.
Author:	Altomare, Ivy\|Hurwitz, Herbert
PMID:	23406528

1474.
Journal:	Oncol Lett. 2013 Feb;5(2):521-526.
Title:	Function and mode of action of cytohesins in the epidermal growth factor pathway in colorectal cancer cells.
Author:	Pan, Tao\|Sun, Junfeng\|Zhou, Jun\|Fu, Zhixuan\|Hu, Yiwang\|Zheng, Shu\|Zhang, Suzhan
PMID:	23420529

1475.
Journal:	Oncol Lett. 2013 Feb;5(2):637-640.
Title:	Bevacizumab-containing regimens after cetuximab failure in Kras wild-type metastatic colorectal carcinoma.
Author:	Lam, Ka On\|Lee, Victor Ho Fun\|Liu, Rico Kin Yin\|Leung, To Wai\|Kwong, Dora Lai Wan
PMID:	23420587

1476.
Journal:	Int J Mol Sci. 2013 Feb 19;14(2):4121-34.
Title:	Polymorphisms in XPD and ERCC1 Associated with Colorectal Cancer Outcome.
Author:	Huang, Ming-Yii\|Wang, Jaw-Yuan\|Huang, Meng-Lin\|Chang, Hui-Jen\|Lin, Shiu-Ru
PMID:	23429196

1477.
Journal:	Genet Med. 2013 Jul;15(7):517-27.
Title:	Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy?
Author:
PMID:	23429431

1478.
Journal:	PLoS One. 2013;8(2):e56205.
Title:	EGFR gene copy number as a prognostic marker in colorectal cancer patients treated with cetuximab or panitumumab: a systematic review and meta analysis.
Author:	Jiang, Zheng\|Li, Chunxiang\|Li, Fuyuan\|Wang, Xishan
PMID:	23441167

1479.
Journal:	PLoS One. 2013;8(2):e56770.
Title:	Telmisartan inhibits cell proliferation by blocking nuclear translocation of ProHB-EGF C-terminal fragment in colon cancer cells.
Author:	Ozeki, Keiji\|Tanida, Satoshi\|Morimoto, Chie\|Inoue, Yoshimasa\|Mizoshita, Tsutomu\|Tsukamoto, Hironobu\|Shimura, Takaya\|Kataoka, Hiromi\|Kamiya, Takeshi\|Nishiwaki, Eiji\|Ishiguro, Hiroshi\|Higashiyama, Shigeki\|Joh, Takashi
PMID:	23451083

1480.
Journal:	J Gastrointest Oncol. 2013 Mar;4(1):72-81.
Title:	The role of EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer.
Author:	Muhammad, Shan\|Jiang, Zheng\|Liu, Zheng\|Kaur, Kavanjit\|Wang, Xishan
PMID:	23451330

1481.
Journal:	Nucl Med Biol. 2013 May;40(4):451-7.
Title:	Zirconium-89 labeled panitumumab: a potential immuno-PET probe for HER1-expressing carcinomas.
Author:	Bhattacharyya, Sibaprasad\|Kurdziel, Karen\|Wei, Ling\|Riffle, Lisa\|Kaur, Gurmeet\|Hill, G Craig\|Jacobs, Paula M\|Tatum, James L\|Doroshow, James H\|Kalen, Joseph D
PMID:	23454247

1482.
Journal:	PLoS One. 2013;8(2):e56666.
Title:	Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.
Author:	Wang, Lihong\|Cao, Hailong\|Lu, Ning\|Liu, Liping\|Wang, Bangmao\|Hu, Tianhui\|Israel, Dawn A\|Peek, Richard M Jr\|Polk, D Brent\|Yan, Fang
PMID:	23457600

1483.
Journal:	J Proteome Res. 2013 Apr 5;12(4):1732-42.
Title:	Proteogenomic analysis of human colon carcinoma cell lines LIM1215, LIM1899, and LIM2405.
Author:	Fanayan, Susan\|Smith, Joshua T\|Lee, Ling Y\|Yan, Fangfei\|Snyder, Michael\|Hancock, William S\|Nice, Edouard
PMID:	23458625

1484.
Journal:	Int J Mol Sci. 2013 Mar 4;14(3):5170-81.
Title:	EGFR Expression and KRAS and BRAF Mutational Status in Intestinal-Type Sinonasal Adenocarcinoma.
Author:	Szablewski, Vanessa\|Solassol, Jerome\|Poizat, Flora\|Larrieux, Marion\|Crampette, Louis\|Mange, Alain\|Bascoul-Mollevi, Caroline\|Costes, Valerie
PMID:	23459231

1485.
Journal:	Hum Pathol. 2013 Aug;44(8):1524-33.
Title:	Altered PTEN function caused by deletion or gene disruption is associated with poor prognosis in rectal but not in colon cancer.
Author:	Bohn, B A\|Mina, S\|Krohn, A\|Simon, R\|Kluth, M\|Harasimowicz, S\|Quaas, A\|Bockhorn, M\|Izbicki, J R\|Sauter, G\|Marx, A\|Stahl, P R
PMID:	23465274

1486.
Journal:	Eur J Cancer. 2013 Jun;49(9):2126-33.
Title:	The KRAS mutation detection within the initial management of patients with metastatic colorectal cancer: a status report in France in 2011.
Author:	Lievre, A\|Artru, P\|Guiu, M\|Laurent-Puig, P\|Merlin, J L\|Sabourin, J C\|Viguier, J\|Bastie, A\|Seronde, A\|Ducreux, M
PMID:	23473612

1487.
Journal:	Crit Rev Oncol Hematol. 2013 Sep;87(3):283-305.
Title:	The contribution of targeted therapy to the neoadjuvant chemoradiation of rectal cancer.
Author:	Torino, Francesco\|Sarmiento, Roberta\|Gasparini, Giampietro
PMID:	23478150

1488.
Journal:	J Egypt Natl Canc Inst. 2013 Mar;25(1):37-41.
Title:	The KRAS StripAssay for detection of KRAS mutation in Egyptian patients with colorectal cancer (CRC): a pilot study.
Author:	Abd El Kader, Yasser\|Emera, Gamal\|Safwat, Ezzat\|Kassem, Heba A\|Kassem, Neemat M
PMID:	23499205

1489.
Journal:	J Egypt Natl Canc Inst. 2013 Mar;25(1):51-6.
Title:	Immunohistochemical assay for detection of K-ras protein expression in metastatic colorectal cancer.
Author:	Elsabah, Mahmoud Tag\|Adel, Iman
PMID:	23499207

1490.
Journal:	PLoS One. 2013;8(3):e58606.
Title:	Salmonella infection upregulates the leaky protein claudin-2 in intestinal epithelial cells.
Author:	Zhang, Yong-guo\|Wu, Shaoping\|Xia, Yinglin\|Sun, Jun
PMID:	23505542

1491.
Journal:	Curr Opin Oncol. 2013 May;25(3):313-24.
Title:	Crosstalk between HER2 signaling and angiogenesis in breast cancer: molecular basis, clinical applications and challenges.
Author:	Alameddine, Raafat S\|Otrock, Zaher K\|Awada, Ahmad\|Shamseddine, Ali
PMID:	23518595

1492.
Journal:	Chem Biol Interact. 2013 Apr 25;203(2):412-22.
Title:	Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells.
Author:	Yu, Sheng-Yi\|Liu, Huei-Fang\|Wang, Su-Pei\|Chang, Chia-Ching\|Tsai, Chuan-Mei\|Chao, Jui-I
PMID:	23523951

1493.
Journal:	Klin Onkol. 2013;26(1):25-30.
Title:	[Molecular biological diagnostics of KRAS and BRAF mutations in patients with colorectal cancer - laboratory experience].
Author:	Robesova, B\|Bajerova, M\|Vasikova, A\|Ostrizkova, L\|Hausnerova, J\|Kyclova, J\|Pospisilova, S\|Mayer, J\|Dvorakova, D
PMID:	23528169

1494.
Journal:	Exp Mol Pathol. 2013 Aug;95(1):74-82.
Title:	Heterogeneity of colorectal cancer (CRC) in reference to KRAS proto-oncogene utilizing WAVE technology.
Author:	Perez, K\|Walsh, R\|Brilliant, K\|Noble, L\|Yakirevich, E\|Breese, V\|Jackson, C\|Chatterjee, D\|Pricolo, V\|Roth, L\|Shah, N\|Cataldo, T\|Safran, H\|Hixson, D\|Quesenberry, P
PMID:	23528430

1495.
Journal:	Asian Pac J Cancer Prev. 2013;14(1):495-8.
Title:	EGFR antisense oligonucleotides encapsulated with nanoparticles decrease EGFR, MAPK1 and STAT5 expression in a human colon cancer cell line.
Author:	Najar, Ahmad Gholamhoseinian\|Pashaei-Asl, Roghiyeh\|Omidi, Yadollah\|Farajnia, Safar\|Nourazarian, Ali Reza
PMID:	23534780

1496.
Journal:	PLoS One. 2013;8(3):e59918.
Title:	TGF-Beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis.
Author:	Geng, Liying\|Chaudhuri, Anathbandhu\|Talmon, Geoffrey\|Wisecarver, James L\|Wang, Jing
PMID:	23536895

1497.
Journal:	PLoS One. 2013;8(3):e59939.
Title:	A new microarray substrate for ultra-sensitive genotyping of KRAS and BRAF gene variants in colorectal cancer.
Author:	Galbiati, Silvia\|Damin, Francesco\|Pinzani, Pamela\|Mancini, Irene\|Vinci, Serena\|Chiari, Marcella\|Orlando, Claudio\|Cremonesi, Laura\|Ferrari, Maurizio
PMID:	23536897

1498.
Journal:	Pathol Res Pract. 2013 Apr;209(4):233-6.
Title:	Mutation analysis of KRAS in primary colorectal cancer and matched metastases by means of highly sensitivity molecular assay.
Author:	Miglio, Umberto\|Mezzapelle, Rosanna\|Paganotti, Alessia\|Allegrini, Sara\|Veggiani, Claudia\|Antona, Jlenia\|Gentilli, Sergio\|Monga, Guido\|Alabiso, Oscar\|Boldorini, Renzo
PMID:	23538047

1499.
Journal:	Transl Oncol. 2013 Apr;6(2):180-6. Epub 2013 Apr 1.
Title:	Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens.
Author:	Yu, Yingjie\|Sarkar, Fazlul H\|Majumdar, Adhip P N
PMID:	23544170

1500.
Journal:	Health Technol Assess. 2013 Apr;17(14):1-237.
Title:	The clinical effectiveness and cost-effectiveness of cetuximab (mono- or combination chemotherapy), bevacizumab (combination with non-oxaliplatin chemotherapy) and panitumumab (monotherapy) for the treatment of metastatic colorectal cancer after first-lin
Author:	Hoyle, M\|Crathorne, L\|Peters, J\|Jones-Hughes, T\|Cooper, C\|Napier, M\|Tappenden, P\|Hyde, C
PMID:	23547747

1501.
Journal:	BMC Cancer. 2013 Apr 1;13:169.
Title:	High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.
Author:	Guedes, Joana G\|Veiga, Isabel\|Rocha, Patricia\|Pinto, Pedro\|Pinto, Carla\|Pinheiro, Manuela\|Peixoto, Ana\|Fragoso, Maria\|Raimundo, Ana\|Ferreira, Paula\|Machado, Manuela\|Sousa, Nuno\|Lopes, Paula\|Araujo, Antonio\|Macedo, Joana\|Alves, Fernando\|Coutinho, Camila\|He
PMID:	23548132

1502.
Journal:	PLoS One. 2013;8(3):e59689.
Title:	Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines.
Author:	Luca, Anna C\|Mersch, Sabrina\|Deenen, Rene\|Schmidt, Stephan\|Messner, Isabelle\|Schafer, Karl-Ludwig\|Baldus, Stephan E\|Huckenbeck, Wolfgang\|Piekorz, Roland P\|Knoefel, Wolfram T\|Krieg, Andreas\|Stoecklein, Nikolas H
PMID:	23555746

1503.
Journal:	Future Oncol. 2013 Apr;9(4):551-60.
Title:	Targeting mechanisms of resistance to anti-EGF receptor therapy in KRAS wild-type colorectal cancer: the path to more personalized medicine.
Author:	Fakih, Marwan
PMID:	23560377

1504.
Journal:	BMC Cancer. 2013 Apr 8;13:183.
Title:	Genetic variations of the A13/A14 repeat located within the EGFR 3' untranslated region have no oncogenic effect in patients with colorectal cancer.
Author:	Sarafan-Vasseur, Nasrin\|Sefrioui, David\|Tougeron, David\|Lamy, Aude\|Blanchard, France\|Le Pessot, Florence\|Di Fiore, Frederic\|Michel, Pierre\|Bezieau, Stephane\|Latouche, Jean-Baptiste\|Frebourg, Thierry\|Sesboue, Richard
PMID:	23565769

1505.
Journal:	J Cancer. 2013;4(4):320-2.
Title:	Rare Though Not Mutually Exclusive: A Report of Three Cases of Concomitant KRAS and BRAF Mutation and a Review of the Literature.
Author:	Sahin, Ibrahim Halil\|Kazmi, Syed M A\|Yorio, Jeffrey T\|Bhadkamkar, Nishin A\|Kee, Bryan K\|Garrett, Christopher R
PMID:	23569465

1506.
Journal:	Eur J Hum Genet. 2013 Dec;21(12):1383-8.
Title:	Oncogenic mutations and microsatellite instability phenotype predict specific anatomical subsite in colorectal cancer patients.
Author:	Corso, Giovanni\|Pascale, Valeria\|Flauti, Giuseppe\|Ferrara, Francesco\|Marrelli, Daniele\|Roviello, Franco
PMID:	23572025

1507.
Journal:	Magy Onkol. 2013 Mar;57(1):56-62.
Title:	[Biomarkers in solid tumors].
Author:	Nagy, Zsuzsanna
PMID:	23573523

1508.
Journal:	J Oncol. 2013;2013:386906.
Title:	Analysis of the mRNA expression of chemotherapy-related genes in colorectal carcinoma using the danenberg tumor profile method.
Author:	Sasaki, Shin\|Watanabe, Toshiyuki\|Nakayama, Hiroshi
PMID:	23577026

1509.
Journal:	Tumour Biol. 2013 Aug;34(4):2109-17.
Title:	Vascular endothelial growth factor receptors 1,3 and caveolin-1 are implicated in colorectal cancer aggressiveness and prognosis--correlations with epidermal growth factor receptor, CD44v6, focal adhesion kinase, and c-Met.
Author:	Garouniatis, Alexandros\|Zizi-Sermpetzoglou, Adamantia\|Rizos, Spyros\|Kostakis, Alkiviadis\|Nikiteas, Nikolaos\|Papavassiliou, Athanasios G
PMID:	23580180

1510.
Journal:	Endoscopy. 2013 Jun;45(6):469-77.
Title:	In vivo molecular imaging with cetuximab, an anti-EGFR antibody, for prediction of response in xenograft models of human colorectal cancer.
Author:	Goetz, M\|Hoetker, M S\|Diken, M\|Galle, P R\|Kiesslich, R
PMID:	23580409

1511.
Journal:	J Agric Food Chem. 2013 May 22;61(20):4873-81.
Title:	Effect of microformulation on the bioactivity of an anthocyanin-rich bilberry pomace extract ( Vaccinium myrtillus L.) in vitro.
Author:	Kropat, Christopher\|Betz, Michael\|Kulozik, Ulrich\|Leick, Sabine\|Rehage, Heinz\|Boettler, Ute\|Teller, Nicole\|Marko, Doris
PMID:	23581244

1512.
Journal:	Mod Pathol. 2013 Sep;26(9):1197-203.
Title:	Immunohistochemical staining with EGFR mutation-specific antibodies: high specificity as a diagnostic marker for lung adenocarcinoma.
Author:	Wen, Yong Hannah\|Brogi, Edi\|Hasanovic, Adnan\|Ladanyi, Marc\|Soslow, Robert A\|Chitale, Dhananjay\|Shia, Jinru\|Moreira, Andre L
PMID:	23599147

1513.
Journal:	Mol Diagn Ther. 2013 Jun;17(3):193-203.
Title:	KRAS and BRAF mutation analysis in colorectal adenocarcinoma specimens with a low percentage of tumor cells.
Author:	Lewandowska, Marzena Anna\|Jozwicki, Wojciech\|Zurawski, Bogdan
PMID:	23606169

1514.
Journal:	Cancer Res Treat. 2013 Mar;45(1):55-62.
Title:	Impact of KRAS Mutation Status on Outcomes in Metastatic Colon Cancer Patients without Anti-Epidermal Growth Factor Receptor Therapy.
Author:	Kim, Seung Tae\|Park, Kyong Hwa\|Kim, Jun Suk\|Shin, Sang Won\|Kim, Yeul Hong
PMID:	23613671

1515.
Journal:	Future Oncol. 2013 Aug;9(8):1207-14.
Title:	Role of beta4 integrin in HER-3-negative, K-RAS wild-type metastatic colorectal tumors receiving cetuximab.
Author:	Scartozzi, Mario\|Giampieri, Riccardo\|Loretelli, Cristian\|Mandolesi, Alessandra\|del Prete, Michela\|Biagetti, Simona\|Alfonsi, Simona\|Faloppi, Luca\|Bianconi, Maristella\|Bittoni, Alessandro\|Bearzi, Italo\|Cascinu, Stefano
PMID:	23617461

1516.
Journal:	BMC Cancer. 2013 Apr 24;13:204.
Title:	Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis.
Author:	Peng, Zhongsheng\|Heath, Jonathon\|Drachenberg, Cinthia\|Raufman, Jean-Pierre\|Xie, Guofeng
PMID:	23617763

1517.
Journal:	N Am J Med Sci. 2013 Mar;5(3):202-6.
Title:	Allele Frequencies of the Epidermal Growth Factor Receptors Polymorphism R521K in Colorectal Cancer Patients and Healthy Subjects Indicate a Risk-Reducing Effect of K521 in Syrian Population.
Author:	Mustafa, Ola Haj\|Hamzeh, Abdul Rezzak\|Ghabreau, Lina\|Akil, Nizar\|Almoustafa, Ala-Eddin\|Alachkar, Amal
PMID:	23626956

1518.
Journal:	Neoplasia. 2013 May;15(5):544-53.
Title:	Cellular immunotherapy for carcinoma using genetically modified EGFR-specific T lymphocytes.
Author:	Zhou, Xikun\|Li, Jing\|Wang, Zhen\|Chen, Zhongwen\|Qiu, Ji\|Zhang, Yinbing\|Wang, Wei\|Ma, Yu\|Huang, Nongyu\|Cui, Kaijun\|Li, Jiong\|Wei, Yu-quan
PMID:	23633926

1519.
Journal:	Discov Med. 2013 Apr;15(83):259-67.
Title:	Personalized cancer treatment and the myth of KRAS wild-type colon tumors.
Author:	Parsons, Barbara L\|Myers, Meagan B
PMID:	23636143

1520.
Journal:	Target Oncol. 2013 Jun;8(2):83-96.
Title:	Role of targeted agents in metastatic colorectal cancer.
Author:	Prenen, Hans\|Vecchione, Loredana\|Van Cutsem, Eric
PMID:	23645285

1521.
Journal:	Anticancer Res. 2013 May;33(5):2239-43.
Title:	Monitoring of circulating tumor cells in patients undergoing surgery for hepatic metastases from colorectal cancer.
Author:	Pesta, Martin\|Fichtl, Jakub\|Kulda, Vlastimil\|Topolcan, Ondrej\|Treska, Vladislav
PMID:	23645782

1522.
Journal:	Genes Chromosomes Cancer. 2013 Aug;52(8):748-52.
Title:	BRAF V600E mutation detection by immunohistochemistry in colorectal carcinoma.
Author:	Affolter, Kajsa\|Samowitz, Wade\|Tripp, Sheryl\|Bronner, Mary P
PMID:	23650027

1523.
Journal:	Clin Chem. 2013 Oct;59(10):1447-56.
Title:	Companion biomarkers: paving the pathway to personalized treatment for cancer.
Author:	Duffy, Michael J\|Crown, John
PMID:	23656699

1524.
Journal:	Cancer. 2013 Aug 1;119(15):2765-70.
Title:	Mutation-specific antibody detects mutant BRAFV600E protein expression in human colon carcinomas.
Author:	Sinicrope, Frank A\|Smyrk, Thomas C\|Tougeron, David\|Thibodeau, Stephen N\|Singh, Shalini\|Muranyi, Andrea\|Shanmugam, Kandavel\|Grogan, Thomas M\|Alberts, Steven R\|Shi, Qian
PMID:	23657789

1525.
Journal:	PLoS One. 2013 May 9;8(5):e62989.
Title:	A novel fully automated molecular diagnostic system (AMDS) for colorectal cancer mutation detection.
Author:	Kitano, Shiro\|Myers, Jamie\|Nakamura, Junko\|Yamane, Akio\|Yamashita, Mami\|Nakayama, Masato\|Tsukahara, Yusuke\|Ushida, Hiroshi\|Liu, Wanqing\|Ratain, Mark J\|Amano, Masahiko
PMID:	23671647

1526.
Journal:	Int J Oncol. 2013 Jul;43(1):141-50.
Title:	Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells.
Author:	Chen, Hui-Jye\|Jiang, Yi-Lin\|Lin, Chung-Ming\|Tsai, Shih-Chang\|Peng, Shu-Fen\|Fushiya, Shinji\|Hour, Mann-Jen\|Yang, Jai-Sing
PMID:	23677180

1527.
Journal:	Bioorg Med Chem Lett. 2013 Jul 1;23(13):3935-41.
Title:	Design, synthesis and biological evaluation of 2-mercapto-3-phenethylquinazoline bearing anilide fragments as potential antitumor agents: molecular docking study.
Author:	Al-Suwaidan, Ibrahim A\|Alanazi, Amer M\|Abdel-Aziz, Alaa A-M\|Mohamed, Menshawy A\|El-Azab, Adel S
PMID:	23683592

1528.
Journal:	Am Soc Clin Oncol Educ Book. 2013. pii: 0011300e115.
Title:	Right drug for the right patient: hurdles and the path forward in colorectal cancer.
Author:	Kopetz, Scott
PMID:	23714474

1529.
Journal:	Lancet Oncol. 2013 Jul;14(8):749-59.
Title:	Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial.
Author:	Seymour, Matthew T\|Brown, Sarah R\|Middleton, Gary\|Maughan, Timothy\|Richman, Susan\|Gwyther, Stephen\|Lowe, Catherine\|Seligmann, Jennifer F\|Wadsley, Jonathan\|Maisey, Nick\|Chau, Ian\|Hill, Mark\|Dawson, Lesley\|Falk, Stephen\|O'Callaghan, Ann\|Benstead, Kim\|Chambe
PMID:	23725851

1530.
Journal:	Med Oncol. 2013;30(3):617.
Title:	KRAS gene mutations in correlation with clinicopathological features of colorectal carcinomas in Indian patient cohort.
Author:	Patil, Harshali\|Korde, Rajesh\|Kapat, Arnab
PMID:	23729268

1531.
Journal:	Cancer Discov. 2013 Jun;3(6):658-73.
Title:	Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer.
Author:	Bardelli, Alberto\|Corso, Simona\|Bertotti, Andrea\|Hobor, Sebastijan\|Valtorta, Emanuele\|Siravegna, Giulia\|Sartore-Bianchi, Andrea\|Scala, Elisa\|Cassingena, Andrea\|Zecchin, Davide\|Apicella, Maria\|Migliardi, Giorgia\|Galimi, Francesco\|Lauricella, Calogero\|Zanon
PMID:	23729478

1532.
Journal:	Int J Mol Med. 2013 Aug;32(2):291-5.
Title:	Induction of apoptosis and the regulation of ErbB signaling by laminarin in HT-29 human colon cancer cells.
Author:	Park, Hee-Kyoung\|Kim, In-Hye\|Kim, Joongkyun\|Nam, Taek-Jeong
PMID:	23739740

1533.
Journal:	Clin Cancer Res. 2013 Aug 1;19(15):4104-13.
Title:	Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy +/- cetuximab.
Author:	Smith, Christopher G\|Fisher, David\|Claes, Bart\|Maughan, Timothy S\|Idziaszczyk, Shelley\|Peuteman, Gilian\|Harris, Rebecca\|James, Michelle D\|Meade, Angela\|Jasani, Bharat\|Adams, Richard A\|Kenny, Sarah\|Kaplan, Richard\|Lambrechts, Diether\|Cheadle, Jeremy P
PMID:	23741067

1534.
Journal:	Gastrointest Cancer Res. 2013 Mar;6(2):47-55.
Title:	Alternate dosing of cetuximab for patients with metastatic colorectal cancer.
Author:	Hubbard, Joleen M\|Alberts, Steven R
PMID:	23745159

1535.
Journal:	Int J Oncol. 2013 Aug;43(2):629-37.
Title:	Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling.
Author:	Chen, Hui-Jye\|Lin, Chung-Ming\|Lee, Chao-Ying\|Shih, Nai-Chen\|Amagaya, Sakae\|Lin, Yung-Chang\|Yang, Jai-Sing
PMID:	23754208

1536.
Journal:	Clin Cancer Res. 2013 Aug 1;19(15):4149-62.
Title:	Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
Author:	Spreafico, Anna\|Tentler, John J\|Pitts, Todd M\|Tan, Aik Choon\|Gregory, Mark A\|Arcaroli, John J\|Klauck, Peter J\|McManus, Martine C\|Hansen, Ryan J\|Kim, Jihye\|Micel, Lindsey N\|Selby, Heather M\|Newton, Timothy P\|McPhillips, Kelly L\|Gustafson, Daniel L\|Degregor
PMID:	23757356

1537.
Journal:	Histopathology. 2013 Aug;63(2):187-93.
Title:	Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma.
Author:	Adackapara, Cheryl A\|Sholl, Lynette M\|Barletta, Justine A\|Hornick, Jason L
PMID:	23763264

1538.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):703-10.
Title:	Off-label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer.
Author:	Al-Marrawi, Mhd Yaser\|Saroya, Bikramajit Singh\|Brennan, Matthew C\|Yang, Zhaohai\|Dykes, Thomas M\|El-Deiry, Wafik S
PMID:	23792568

1539.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):699-702.
Title:	Contradictory KRAS mutation test results in a patient with metastatic colon cancer: a clinical dilemma in the era of personalized medicine.
Author:	Lamparella, Nicholas E\|Saroya, Bikramajit S\|Yang, Zhaohai\|Sarwani, Nabeel E\|El-Deiry, Wafik S
PMID:	23792572

1540.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S599-606.
Title:	Associations between genetic polymorphisms of epidermal growth factor receptor (EGFR) and survival of colorectal cancer (CRC) patients treated with 5-fluorouracil-based chemotherapy.
Author:	Lai, Ching-Yu\|Sung, Fung-Chang\|Hsieh, Ling-Ling\|Tang, Reiping\|Chiou, Hung-Yi\|Wu, Fang-Yang\|Yeh, Chih-Ching
PMID:	23800895

1541.
Journal:	Eur J Nucl Med Mol Imaging. 2013 Oct;40(11):1635-44.
Title:	Clinical significance of VEGFR-2 and (1)(8)F-FDG PET/CT SUVmax pretreatment score in predicting the long-term outcome of patients with locally advanced rectal cancer treated with neoadjuvant therapy.
Author:	Sole, Claudio V\|Calvo, Felipe A\|Alvarez, Emilio\|Peligros, Isabel\|Garcia-Alfonso, Pilar\|Ferrer, Carlos\|Ochoa, Enrique\|Herranz, Rafael\|Carreras, Jose L
PMID:	23801169

1542.
Journal:	Crit Rev Oncol Hematol. 2013 Nov;88(2):272-83.
Title:	Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation.
Author:	Giampieri, Riccardo\|Scartozzi, Mario\|Del Prete, Michela\|Maccaroni, Elena\|Bittoni, Alessandro\|Faloppi, Luca\|Bianconi, Maristella\|Cecchini, Luca\|Cascinu, Stefano
PMID:	23806981

1543.
Journal:	J Cancer Res Clin Oncol. 2013 Oct;139(10):1615-24.
Title:	MicroRNAs targeting EGFR signalling pathway in colorectal cancer.
Author:	Mlcochova, Jitka\|Faltejskova, Petra\|Nemecek, Radim\|Svoboda, Marek\|Slaby, Ondrej
PMID:	23817698

1544.
Journal:	PLoS One. 2013 Jun 18;8(6):e66302.
Title:	Expression of Epidermal Growth Factor Receptor Detected by Cetuximab Indicates Its Efficacy to Inhibit In Vitro and In Vivo Proliferation of Colorectal Cancer Cells.
Author:	Shigeta, Kohei\|Hayashida, Tetsu\|Hoshino, Yoshinori\|Okabayashi, Koji\|Endo, Takashi\|Ishii, Yoshiyuki\|Hasegawa, Hirotoshi\|Kitagawa, Yuko
PMID:	23824671

1545.
Journal:	PLoS One. 2013 Jun 25;8(6):e67142.
Title:	Layered signaling regulatory networks analysis of gene expression involved in malignant tumorigenesis of non-resolving ulcerative colitis via integration of cross-study microarray profiles.
Author:	Fan, Shengjun\|Pan, Zhenyu\|Geng, Qiang\|Li, Xin\|Wang, Yefan\|An, Yu\|Xu, Yan\|Tie, Lu\|Pan, Yan\|Li, Xuejun
PMID:	23825635

1546.
Journal:	Clin Chim Acta. 2013 Oct 21;425:1-2.
Title:	Companion-diagnostic testing limited to KRAS codons 12 and 13 misses 17% of potentially relevant RAS mutations in colorectal cancer.
Author:	Netzel, Brian C\|Grebe, Stefan K G
PMID:	23832066

1547.
Journal:	Pathol Biol (Paris). 2013 Dec;61(6):273-6.
Title:	Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer.
Author:	Marchoudi, N\|Amrani Hassani Joutei, H\|Jouali, F\|Fekkak, J\|Rhaissi, H
PMID:	23849768

1548.
Journal:	Gan To Kagaku Ryoho. 2013 Jul;40(7):897-900.
Title:	[Effect of magnesium supplementation on early-stage hypomagnesemia in patients treated with cetuximab].
Author:	Demizu, Mutsuko\|Ueda, Hiroshi\|Osawa, Machiko\|Chihara, Satomi\|Igarashi, Tsutomu\|Yano, Keiko\|Kimura, Fumihiko\|Tanaka, Nobuo\|Hiratsuka, Masahiro
PMID:	23863731

1549.
Journal:	Biomed Res Int. 2013;2013:976765.
Title:	Loss of RASSF1A expression in colorectal cancer and its association with K-ras status.
Author:	Cao, Dan\|Chen, Ye\|Tang, Yuan\|Peng, Xing-Chen\|Dong, Hang\|Li, Long-Hao\|Cheng, Ke\|Ge, Jun\|Liu, Ji-Yan
PMID:	23865079

1550.
Journal:	Mol Cancer. 2013 Jul 17;12:78.
Title:	TNFalpha and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells.
Author:	Straus, Daniel S
PMID:	23866118

1551.
Journal:	J Clin Invest. 2013 Aug;123(8):3459-71.
Title:	Metastasis-associated PRL-3 induces EGFR activation and addiction in cancer cells.
Author:	Al-Aidaroos, Abdul Qader Omer\|Yuen, Hiu Fung\|Guo, Ke\|Zhang, Shu Dong\|Chung, Tae-Hoon\|Chng, Wee Joo\|Zeng, Qi
PMID:	23867504

1552.
Journal:	Eur J Cancer. 2013 Oct;49(15):3344-52.
Title:	Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer.
Author:	Jain, Ajay\|Poonia, Bhawna\|So, Edward C\|Vyzasatya, Ravi\|Burch, Erin E\|Olsen, Henrik S\|Merigeon, Emmanuel Y\|Block, David S\|Zhang, Xiaoyu\|Schulze, Dan H\|Hanna, Nader N\|Twadell, William S\|Yfantis, Harris G\|Chan, Siaw L\|Cai, Ling\|Strome, Scott E
PMID:	23871153

1553.
Journal:	PLoS One. 2013 Jul 9;8(7):e68022.
Title:	Colorectal cancer patients with low abundance of KRAS mutation may benefit from EGFR antibody therapy.
Author:	Yu, Shaorong\|Xiao, Xia\|Lu, Jianwei\|Qian, Xiaoping\|Liu, Baorui\|Feng, Jifeng
PMID:	23874486

1554.
Journal:	Eur J Cancer. 2013 Oct;49(15):3076-82.
Title:	Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center.
Author:	Wiesweg, Marcel\|Ting, Saskia\|Reis, Henning\|Worm, Karl\|Kasper, Stefan\|Tewes, Mitra\|Welt, Anja\|Richly, Heike\|Meiler, Johannes\|Bauer, Sebastian\|Hense, Jorg\|Gauler, Thomas C\|Kohler, Jens\|Eberhardt, Wilfried E\|Darwiche, Kaid\|Freitag, Lutz\|Stamatis, Georgios\|Br
PMID:	23876834

1555.
Journal:	Bioorg Med Chem. 2013 Sep 1;21(17):5012-20.
Title:	Exploring pyrimidine-substituted curcumin analogues: design, synthesis and effects on EGFR signaling.
Author:	Qiu, Peiju\|Xu, Lingling\|Gao, Lei\|Zhang, Meng\|Wang, Shixi\|Tong, Sheng\|Sun, Yue\|Zhang, Lijuan\|Jiang, Tao
PMID:	23880083

1556.
Journal:	Harefuah. 2013 Jun;152(6):326-9, 369.
Title:	[Correlation between the presence of Kras mutation and the presence of the proteins epiregulin and amphiregulin in colon cancer tissue].
Author:	Levi, Yosef\|Barshack, Iris\|Avivi, Kamila\|Bar-ILan, Dalia\|Gutman, Mordechai\|Aderka, Dan\|Berger, Raanan\|Yacobi, Rinat
PMID:	23885463

1557.
Journal:	Yonsei Med J. 2013 Sep;54(5):1194-201.
Title:	Proteinuria as a risk factor for mortality in patients with colorectal cancer.
Author:	Kim, Min Jee\|Kang, Yong Un\|Kim, Chang Seong\|Choi, Joon Seok\|Bae, Eun Hui\|Ma, Seong Kwon\|Kweon, Sun-Seog\|Kim, Soo Wan
PMID:	23918569

1558.
Journal:	PLoS One. 2013 Jul 26;8(7):e69604.
Title:	Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis.
Author:	McCourt, Clare M\|McArt, Darragh G\|Mills, Ken\|Catherwood, Mark A\|Maxwell, Perry\|Waugh, David J\|Hamilton, Peter\|O'Sullivan, Joe M\|Salto-Tellez, Manuel
PMID:	23922754

1559.
Journal:	Onco Targets Ther. 2013 Jul 24;6:967-76.
Title:	Overexpression of epidermal growth factor receptor as a prognostic factor in colorectal cancer on the basis of the Allred scoring system.
Author:	Rokita, Marta\|Stec, Rafal\|Bodnar, Lubomir\|Charkiewicz, Radoslaw\|Korniluk, Jan\|Smoter, Marta\|Cichowicz, Marzena\|Chyczewski, Lech\|Niklinski, Jacek\|Kozlowski, Wojciech\|Szczylik, Cezary
PMID:	23926437

1560.
Journal:	Cancer Med. 2013 Jun;2(3):296-304.
Title:	EGFR, KRAS, BRAF, and HER-2 molecular status in brain metastases from 77 NSCLC patients.
Author:	Villalva, Claire\|Duranton-Tanneur, Valerie\|Guilloteau, Karline\|Burel-Vandenbos, Fanny\|Wager, Michel\|Doyen, Jerome\|Levillain, Pierre Marie\|Fontaine, Denys\|Blons, Helene\|Pedeutour, Florence\|Karayan-Tapon, Lucie
PMID:	23930206

1561.
Journal:	Virchows Arch. 2013 Oct;463(4):509-23.
Title:	Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis.
Author:	Neumann, Jens\|Wehweck, Laura\|Maatz, Susanne\|Engel, Jutta\|Kirchner, Thomas\|Jung, Andreas
PMID:	23934607

1562.
Journal:	PLoS One. 2013 Jul 25;8(7):e68945.
Title:	Performance and cost efficiency of KRAS mutation testing for metastatic colorectal cancer in routine diagnosis: the MOKAECM study, a nationwide experience.
Author:	Blons, Helene\|Rouleau, Etienne\|Charrier, Nathanael\|Chatellier, Gilles\|Cote, Jean-Francois\|Pages, Jean-Christophe\|de Fraipont, Florence\|Boyer, Jean-Christophe\|Merlio, Jean Philippe\|Morel, Alain\|Gorisse, Marie-Claude\|de Cremoux, Patricia\|Leroy, Karen\|Milano
PMID:	23935912

1563.
Journal:	Biomaterials. 2013 Nov;34(34):8756-65.
Title:	Targeting colorectal cancer cells with single-walled carbon nanotubes conjugated to anticancer agent SN-38 and EGFR antibody.
Author:	Lee, Pei-Chi\|Chiou, Yu-Chi\|Wong, Jau-Min\|Peng, Cheng-Liang\|Shieh, Ming-Jium
PMID:	23937913

1564.
Journal:	Onco Targets Ther. 2013 Aug 5;6:1057-64.
Title:	454 next generation-sequencing outperforms allele-specific PCR, Sanger sequencing, and pyrosequencing for routine KRAS mutation analysis of formalin-fixed, paraffin-embedded samples.
Author:	Altimari, Annalisa\|de Biase, Dario\|De Maglio, Giovanna\|Gruppioni, Elisa\|Capizzi, Elisa\|Degiovanni, Alessio\|D'Errico, Antonia\|Pession, Annalisa\|Pizzolitto, Stefano\|Fiorentino, Michelangelo\|Tallini, Giovanni
PMID:	23950653

1565.
Journal:	Cancer Chemother Pharmacol. 2013 Oct;72(4):767-75.
Title:	Effects of pemetrexed, gefitinib, and their combination on human colorectal cancer cells.
Author:	Zhang, Guanzhong\|Xie, Xiaodong\|Liu, Tianyi\|Yang, Jihua\|Jiao, Shunchang
PMID:	23959460

1566.
Journal:	Mol Cancer Ther. 2013 Oct;12(10):2121-34.
Title:	Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.
Author:	Mazard, Thibault\|Causse, Annick\|Simony, Joelle\|Leconet, Wilhem\|Vezzio-Vie, Nadia\|Torro, Adeline\|Jarlier, Marta\|Evrard, Alexandre\|Del Rio, Maguy\|Assenat, Eric\|Martineau, Pierre\|Ychou, Marc\|Robert, Bruno\|Gongora, Celine
PMID:	23960095

1567.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Aug;16(8):753-8.
Title:	[Association of epithermal growth factor receptor expression and its downstream gene mutation status with radiosensitivity of colorectal carcinoma cell lines in vitro].
Author:	Zuo, Zhi-gui\|Yu, Zhi-qi\|Gao, Xian-hua\|Wang, Hao\|Zhang, Chang\|Liu, Qi-zhi\|Han, Yi-fang\|Chen, Li-ping\|Zhang, Xiao-qing\|Fu, Chuan-gang
PMID:	23980047

1568.
Journal:	Zhonghua Zhong Liu Za Zhi. 2013 Apr;35(4):277-81.
Title:	[Expression of molecular markers detected by immunohistochemistry and risk of lymph node metastasis in stage T1 and T2 colorecrectal cancers].
Author:	Wang, Fu-long\|Wan, De-sen\|Lu, Zhen-hai\|Fang, Yu-jing\|Li, Li-ren\|Chen, Gong\|Wu, Xiao-jun\|Ding, Pei-rong\|Kong, Ling-heng\|Lin, Jun-zhong\|Pan, Zhi-zhong
PMID:	23985256

1569.
Journal:	J Cell Sci. 2013 Nov 1;126(Pt 21):4939-49.
Title:	Functional expression of the voltage-gated Na(+)-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells.
Author:	Campbell, Thomas M\|Main, Martin J\|Fitzgerald, Elizabeth M
PMID:	23986482

1570.
Journal:	Biomed Res Int. 2013;2013:546318.
Title:	The role of epidermal growth factor receptor in cancer metastasis and microenvironment.
Author:	Sasaki, Takamitsu\|Hiroki, Kuniyasu\|Yamashita, Yuichi
PMID:	23986907

1571.
Journal:	PLoS One. 2013 Aug 22;8(8):e73175.
Title:	Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinoma.
Author:	Wang, Quan\|Wei, Feng\|Li, Chunsheng\|Lv, Guoyue\|Wang, Guangyi\|Liu, Tongjun\|Bellail, Anita C\|Hao, Chunhai
PMID:	23991179

1572.
Journal:	J Gastrointest Oncol. 2013 Sep;4(3):245-52.
Title:	Status of targeted therapies in the adjuvant treatment of colon cancer.
Author:	Nelson, Valerie M\|Benson, Al B 3rd
PMID:	23997937

1573.
Journal:	J Gastrointest Oncol. 2013 Sep;4(3):308-18.
Title:	Markers of resistance to anti-EGFR therapy in colorectal cancer.
Author:	Shaib, Walid\|Mahajan, Reena\|El-Rayes, Bassel
PMID:	23997942

1574.
Journal:	Int J Biol Markers. 2013 Dec 17;28(4):e393-7.
Title:	K-RAS mutation profile in Puerto Rican patients with colorectal cancer: trends from April 2009 to January 2011.
Author:	Ruiz-Candelaria, Yelitza\|Miranda-Diaz, Christine\|Hunter-Mellado, Robert F
PMID:	23999847

1575.
Journal:	Biol Sex Differ. 2013 Sep 10;4(1):17.
Title:	Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study.
Author:	Wangefjord, Sakarias\|Sundstrom, Magnus\|Zendehrokh, Nooreldin\|Lindquist, Kajsa Ericson\|Nodin, Bjorn\|Jirstrom, Karin\|Eberhard, Jakob
PMID:	24020794

1576.
Journal:	Anticancer Res. 2013 Sep;33(9):3753-8.
Title:	Combination of the EGFR tyrosine kinase inhibitor AG1478 and 5-FU: no synergistic effect on EGFR phosphorylation, cell proliferation and apoptosis induction.
Author:	Yagublu, Vugar\|Ahmadova, Zhala\|Hajiyeva, Yegana\|Hafner, Mathias\|Keese, Michael
PMID:	24023306

1577.
Journal:	Anticancer Res. 2013 Sep;33(9):3905-10.
Title:	Circulating tumor cell (CTC) count and epithelial growth factor receptor expression on CTCs as biomarkers for cetuximab efficacy in advanced colorectal cancer.
Author:	Kuboki, Yasutoshi\|Matsusaka, Satoshi\|Minowa, Sayuri\|Shibata, Harumi\|Suenaga, Mitsukuni\|Shinozaki, Eiji\|Mizunuma, Nobuyuki\|Ueno, Masashi\|Yamaguchi, Toshiharu\|Hatake, Kiyohiko
PMID:	24023327

1578.
Journal:	N Engl J Med. 2013 Sep 12;369(11):1023-34.
Title:	Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer.
Author:	Douillard, Jean-Yves\|Oliner, Kelly S\|Siena, Salvatore\|Tabernero, Josep\|Burkes, Ronald\|Barugel, Mario\|Humblet, Yves\|Bodoky, Gyorgy\|Cunningham, David\|Jassem, Jacek\|Rivera, Fernando\|Kocakova, Ilona\|Ruff, Paul\|Blasinska-Morawiec, Maria\|Smakal, Martin\|Canon, J
PMID:	24024839

1579.
Journal:	Cancer Biol Ther. 2013 Oct 1;14(10):877-8.
Title:	Multi-kinase modulation for colon cancer therapy.
Author:	Dent, Paul
PMID:	24025253

1580.
Journal:	Cancer Biol Ther. 2013 Dec;14(12):1143-6.
Title:	The S492R EGFR ectodomain mutation is never detected in KRAS wild-type colorectal carcinoma before exposure to EGFR monoclonal antibodies.
Author:	Esposito, Claudia\|Rachiglio, Anna Maria\|La Porta, Maria Libera\|Sacco, Alessandra\|Roma, Cristin\|Iannaccone, Alessia\|Tatangelo, Fabiana\|Forgione, Laura\|Pasquale, Raffaella\|Barbaro, Americo\|Botti, Gerardo\|Ciardiello, Fortunato\|Normanno, Nicola
PMID:	24025416

1581.
Journal:	World J Surg Oncol. 2013 Sep 13;11:226.
Title:	Evaluation of the immune factors in the tumor environment before and after the treatment of cetuximab combined with chemotherapy.
Author:	Zhu, Yanyun\|Li, Jie\|Jing, Fangfang\|Ji, Tiefeng\|Guo, Xiaoqin\|Yang, Junlan\|Jiao, Shunchang
PMID:	24028754

1582.
Journal:	Mol Cancer Ther. 2013 Nov;12(11):2483-93.
Title:	The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells.
Author:	Sreevalsan, Sandeep\|Safe, Stephen
PMID:	24030632

1583.
Journal:	Neoplasma. 2013 Sep 20.
Title:	The role of tumor markers and biomarkers in colorectal cancer.
Author:	Lech, G\|Slotwinski, R\|Krasnodebski, I W
PMID:	24050544

1584.
Journal:	Clin Colorectal Cancer. 2013 Dec;12(4):267-274.e2.
Title:	The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab.
Author:	Strimpakos, Alexios\|Pentheroudakis, George\|Kotoula, Vassiliki\|De Roock, Wendy\|Kouvatseas, George\|Papakostas, Pavlos\|Makatsoris, Thomas\|Papamichael, Demetris\|Andreadou, Anna\|Sgouros, Joseph\|Zizi-Sermpetzoglou, Adamantia\|Kominea, Athina\|Televantou, Despina\|
PMID:	24050852

1585.
Journal:	Radiat Oncol. 2013 Sep 23;8:219.
Title:	Combined effects of C225 and 125-iodine seed radiation on colorectal cancer cells.
Author:	Liu, Jingjia\|Wang, Hao\|Qu, Ang\|Li, Jinna\|Zhao, Yong\|Wang, Junjie
PMID:	24053278

1586.
Journal:	Clin Ther. 2013 Sep;35(9):1282-303.
Title:	Epidermal growth factor receptor: pathway, therapies, and pipeline.
Author:	Goffin, John R\|Zbuk, Kevin
PMID:	24054705

1587.
Journal:	Rom J Morphol Embryol. 2013;54(3):567-74.
Title:	K-ras gene mutation status in colorectal cancer: comparative analysis of pyrosequencing and PCR-RFLP.
Author:	Dobre, Maria\|Comanescu, Maria\|Arsene, D\|Iosif, Cristina\|Bussolati, G
PMID:	24068405

1588.
Journal:	PLoS One. 2013 Sep 19;8(9):e74994.
Title:	Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling.
Author:	de Souza, Waldemir F\|Fortunato-Miranda, Natalia\|Robbs, Bruno K\|de Araujo, Wallace M\|de-Freitas-Junior, Julio C\|Bastos, Lilian G\|Viola, Joao P B\|Morgado-Diaz, Jose A
PMID:	24069372

1589.
Journal:	Drugs Today (Barc). 2013 Sep;49(9):523-35.
Title:	Afatinib for the treatment of patients with EGFR-positive non-small cell lung cancer.
Author:	Bowles, D W\|Weickhardt, A\|Jimeno, A
PMID:	24086949

1590.
Journal:	Future Oncol. 2013 Oct;9(10):1587-94.
Title:	Novel oncoprotein EPS8: a new target for anticancer therapy.
Author:	Li, Yu-Hua\|Xue, Tong-Yuan\|He, Ying-Zhi\|Du, Jing-Wen
PMID:	24106906

1591.
Journal:	Mol Cancer Ther. 2013 Dec;12(12):2950-61.
Title:	BRAF V600E is a determinant of sensitivity to proteasome inhibitors.
Author:	Zecchin, Davide\|Boscaro, Valentina\|Medico, Enzo\|Barault, Ludovic\|Martini, Miriam\|Arena, Sabrina\|Cancelliere, Carlotta\|Bartolini, Alice\|Crowley, Emily H\|Bardelli, Alberto\|Gallicchio, Margherita\|Di Nicolantonio, Federica
PMID:	24107445

1592.
Journal:	Clin Cancer Res. 2013 Dec 15;19(24):6751-65.
Title:	Increased TGF-alpha as a mechanism of acquired resistance to the anti-EGFR inhibitor cetuximab through EGFR-MET interaction and activation of MET signaling in colon cancer cells.
Author:	Troiani, Teresa\|Martinelli, Erika\|Napolitano, Stefania\|Vitagliano, Donata\|Ciuffreda, Loreta Pia\|Costantino, Sara\|Morgillo, Floriana\|Capasso, Anna\|Sforza, Vincenzo\|Nappi, Anna\|De Palma, Raffaele\|D'Aiuto, Elena\|Berrino, Liberato\|Bianco, Roberto\|Ciardiello,
PMID:	24122793

1593.
Journal:	Ann Oncol. 2013 Dec;24(12):3123-8.
Title:	HER2 in high-risk rectal cancer patients treated in EXPERT-C, a randomized phase II trial of neoadjuvant capecitabine and oxaliplatin (CAPOX) and chemoradiotherapy (CRT) with or without cetuximab.
Author:	Sclafani, F\|Roy, A\|Cunningham, D\|Wotherspoon, A\|Peckitt, C\|Gonzalez de Castro, D\|Tabernero, J\|Glimelius, B\|Cervantes, A\|Eltahir, Z\|Oates, J\|Chau, I
PMID:	24146218

1594.
Journal:	World J Gastroenterol. 2013 Oct 14;19(38):6315-8.
Title:	Epidermal growth factor receptor and metastatic colorectal cancer: insights into target therapies.
Author:	de Mello, Ramon Andrade\|Marques, Andrea Marin\|Araujo, Antonio
PMID:	24151349

1595.
Journal:	BMC Med Genomics. 2013 Oct 23;6:43.
Title:	Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway.
Author:	Wormald, Samuel\|Milla, Liz\|O'Connor, Liam
PMID:	24152305

1596.
Journal:	Medicina (B Aires). 2013;73(5):417-22.
Title:	[Clinical-pathological features and gene profile in colorectal cancer].
Author:	Perazzo, Florencia\|Piaggio, Fernando\|Krupitzki, Hugo\|Garcia, Alejandro\|Avagnina, Alejandra\|Elsner, Boris\|Denninghoff, Valeria
PMID:	24152396

1597.
Journal:	Chirurgia (Bucur). 2013 Sep-Oct;108(5):611-5.
Title:	Morphological and immunohistochemical criteria of tissue response to radiotherapy in rectal cancer.
Author:	Ionescu, S\|Bratucu, E\|Zurac, S\|Staniceanu, F\|Patrascu, Tr\|Burcos, Tr\|Herlea, V\|Degeratu, D\|Popa, I\|Cristian, D
PMID:	24157103

1598.
Journal:	J Natl Compr Canc Netw. 2013 Sep;11 Suppl 4:S18-27.
Title:	Emerging treatments in recurrent and metastatic colorectal cancer.
Author:	Ciombor, Kristen Keon\|Bekaii-Saab, Tanios
PMID:	24158967

1599.
Journal:	J Natl Compr Canc Netw. 2013 Sep;11 Suppl 4:S9-17.
Title:	Multigene assays in metastatic colorectal cancer.
Author:	Deeb, Kristin K\|Sram, Jakub P\|Gao, Hanlin\|Fakih, Marwan G
PMID:	24158971

1600.
Journal:	BMC Cancer. 2013 Oct 30;13:511.
Title:	EGF receptor and COX-1/COX-2 enzyme proteins as related to corresponding mRNAs in human per-operative biopsies of colorectal cancer.
Author:	Asting, Annika Gustafsson\|Farivar, Ava\|Iresjo, Britt-Marie\|Svensson, Helena\|Gustavsson, Bengt\|Lundholm, Kent
PMID:	24171795

1601.
Journal:	BMC Cancer. 2013 Nov 2;13:518.
Title:	Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer.
Author:	Khong, Tak L\|Thairu, Ngayu\|Larsen, Helene\|Dawson, Peter M\|Kiriakidis, Serafim\|Paleolog, Ewa M
PMID:	24180698

1602.
Journal:	Gan To Kagaku Ryoho. 2013 Oct;40(10):1393-5.
Title:	[A case study of stable disease after hepatic arterial infusion chemotherapy in a patient with systemic chemotherapy-resistant unresectable hepatic metastases of colon cancer].
Author:	Goi, Takanori\|Nakazawa, Toshiyuki\|Koneri, Kenji\|Murai, Atomu\|Yamaguchi, Akio
PMID:	24196078

1603.
Journal:	Cancer Genet. 2013 Sep-Oct;206(9-10):330-9.
Title:	Low frequency KRAS mutations in colorectal cancer patients and the presence of multiple mutations in oncogenic drivers in non-small cell lung cancer patients.
Author:	Jiang, Liyan\|Huang, Jiaqi\|Morehouse, Chris\|Zhu, Wei\|Korolevich, Susana\|Sui, Dan\|Ge, Xiaoxiao\|Lehmann, Kim\|Liu, Zheng\|Kiefer, Christine\|Czapiga, Meggan\|Su, Xinying\|Brohawn, Philip\|Gu, Yi\|Higgs, Brandon W\|Yao, Yihong
PMID:	24200637

1604.
Journal:	Neoplasia. 2013 Oct;15(10):1196-206.
Title:	Sym004, a novel EGFR antibody mixture, can overcome acquired resistance to cetuximab.
Author:	Iida, Mari\|Brand, Toni M\|Starr, Megan M\|Li, Chunrong\|Huppert, Evan J\|Luthar, Neha\|Pedersen, Mikkel W\|Horak, Ivan D\|Kragh, Michael\|Wheeler, Deric L
PMID:	24204198

1605.
Journal:	PLoS One. 2013 Oct 25;8(10):e76906.
Title:	Concomitant tumor expression of EGFR and TATI/SPINK1 associates with better prognosis in colorectal cancer.
Author:	Koskensalo, Selja\|Louhimo, Johanna\|Hagstrom, Jaana\|Lundin, Mikael\|Stenman, Ulf-Hakan\|Haglund, Caj
PMID:	24204699

1606.
Journal:	J Chem Inf Model. 2013 Dec 23;53(12):3123-6.
Title:	Computational modeling of an epidermal growth factor receptor single-mutation resistance to cetuximab in colorectal cancer treatment.
Author:	Buch, Ignasi\|Ferruz, Noelia\|De Fabritiis, Gianni
PMID:	24219403

1607.
Journal:	Anticancer Res. 2013 Nov;33(11):4995-8.
Title:	Predicting skin toxicity according to EGFR polymorphisms in patients with colorectal cancer receiving antibody against EGFR.
Author:	Saito, Rie\|Suzuki, Hideo\|Yamada, Takeshi\|Endo, Shinji\|Moriwaki, Toshikazu\|Ueno, Takunori\|Hirose, Mitsuaki\|Hirai, Sachiko\|Yamato, Kenji\|Mizokami, Yuji\|Hyodo, Ichinosuke
PMID:	24222141

1608.
Journal:	J Natl Compr Canc Netw. 2013 Nov;11(11):1343-53.
Title:	Translating genomics in cancer care.
Author:	Bombard, Yvonne\|Bach, Peter B\|Offit, Kenneth
PMID:	24225968

1609.
Journal:	Cancer Manag Res. 2013 Nov 21;5:387-400.
Title:	Personalized treatment for advanced colorectal cancer: KRAS and beyond.
Author:	Patel, Gargi Surendra\|Karapetis, Christos S
PMID:	24294007

1610.
Journal:	Front Oncol. 2013 Nov 15;3:281.
Title:	Toward a Molecular Classification of Colorectal Cancer: The Role of BRAF.
Author:	Thiel, Alexandra\|Ristimaki, Ari
PMID:	24298448

1611.
Journal:	PLoS One. 2013 Nov 28;8(11):e81514.
Title:	NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling.
Author:	Tanksley, Jarred P\|Chen, Xi\|Coffey, Robert J
PMID:	24312311

1612.
Journal:	Cancer Biol Ther. 2013 Dec;14(12):1075-6.
Title:	Not all antibodies are equal.
Author:	Booth, Laurence
PMID:	24317328

1613.
Journal:	BMC Cancer. 2013 Dec 13;13:599.
Title:	The prognostic values of EGFR expression and KRAS mutation in patients with synchronous or metachronous metastatic colorectal cancer.
Author:	Huang, Ching-Wen\|Tsai, Hsiang-Lin\|Chen, Yi-Ting\|Huang, Chun-Ming\|Ma, Cheng-Jen\|Lu, Chien-Yu\|Kuo, Chao-Hung\|Wu, Deng-Chyang\|Chai, Chee-Yin\|Wang, Jaw-Yuan
PMID:	24330663

1614.
Journal:	PLoS One. 2013 Dec 10;8(12):e81628.
Title:	Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.
Author:	Shen, Yinchen\|Wang, Jianfei\|Han, Xiaohong\|Yang, Hongying\|Wang, Shuai\|Lin, Dongmei\|Shi, Yuankai
PMID:	24339949

1615.
Journal:	Biomed Res Int. 2013;2013:385087.
Title:	Detection of EGFR mutations by TaqMan mutation detection assays powered by competitive allele-specific TaqMan PCR technology.
Author:	Roma, Cristin\|Esposito, Claudia\|Rachiglio, Anna Maria\|Pasquale, Raffaella\|Iannaccone, Alessia\|Chicchinelli, Nicoletta\|Franco, Renato\|Mancini, Rita\|Pisconti, Salvatore\|De Luca, Antonella\|Botti, Gerardo\|Morabito, Alessandro\|Normanno, Nicola
PMID:	24364033

1616.
Journal:	Gan To Kagaku Ryoho. 2013 Nov;40(12):1714-6.
Title:	[Outcomes of patients with small bowel carcinoma treated with appropriate chemotherapy selected on the basis of genetic analysis findings].
Author:	Suzuki, Okihide\|Ishibashi, Keiichiro\|Imaizumi, Hideko\|Amano, Kunihiko\|Hatano, Satoshi\|Matsuzawa, Takeaki\|Ogita, Tomohiko\|Kuwabara, Koki\|Sobajima, Jun\|Ishiguro, Toru\|Higashi, Morihiro\|Fukuchi, Minoru\|Kumamoto, Keisuke\|Baba, Hiroyuki\|Kumagai, Yoichi\|Tsuji,
PMID:	24393898

1617.
Journal:	Gan To Kagaku Ryoho. 2013 Nov;40(12):2005-7.
Title:	[A case of advanced colorectal carcinoma with aggressively growing liver metastases successfully managed with the induction of cetuximab single-agent therapy].
Author:	Tanimine, Naoki\|Hinoi, Takao\|Egi, Hiroyuki\|Shimomura, Manabu\|Adachi, Tomohiro\|Saito, Yasufumi\|Sawada, Hiroyuki\|Miguchi, Masashi\|Niitsu, Hiroaki\|Mukai, Shoichiro\|Ohdan, Hideki
PMID:	24393994

1618.
Journal:	Front Oncol. 2014 Jan 16;3:326.
Title:	Functions and Regulation of the PTEN Gene in Colorectal Cancer.
Author:	Molinari, Francesca\|Frattini, Milo
PMID:	24475377

1619.
Journal:	Vopr Onkol. 2013;59(6):751-5.
Title:	[The frequency and spectrum of KRAS mutations in metastatic colorectal cancer].
Author:	Mazurenko, N N\|Gagarin, I M\|Tsyganova, I V\|Mochal'nikova, V V\|Breder, V V
PMID:	24624786

1620.
Journal:	Mol Clin Oncol. 2013 Mar;1(2):291-296.
Title:	Analysis of the anatomic subsites, gender and age in unresectable advanced colorectal carcinomas in Tochigi, Japan suggests a shift in location towards the right side colon in elderly patients treated with cetuximab.
Author:	Tanaka, Toshio\|Ichikawa, Kazuhito\|Maruoka, Takashi\|Tomita, Shigeki\|Ueda, Hirofumi\|Yamaguchi, Takeshi\|Shida, Yosuke\|Kato, Hiroyuki\|Nagata, Hitoshi\|Kubota, Keiichi\|Akimoto, Naohiko\|Sakamoto, Chouitsu\|Imura, Johji\|Arita, Munefumi\|Tanaka, Hiroyuki\|Okamoto, Yo
PMID:	24649163

1621.
Journal:	Gastroenterol Hepatol Bed Bench. 2013 Winter;6(1):6-13.
Title:	Clinical implications of BRAF mutation test in colorectal cancer.
Author:	Nazemalhosseini Mojarad, Ehsan\|Farahani, Roya Kishani\|Haghighi, Mahdi Montazer\|Aghdaei, Hamid Asadzadeh\|Kuppen, Peter Jk\|Zali, Mohammad Reza
PMID:	24834238

1622.
Journal:	Gastroenterol Hepatol Bed Bench. 2013;6(Suppl 1):S32-8.
Title:	Different frequency of epidermal growth factor rs76189946 polymorphism genotype in an Iranian colorectal cancer.
Author:	Chaleshi, Vahid\|Savabkar, Sanaz\|Dolatmoradi, Hesamodin\|Haghighi, Mahdi Montazer\|Maryan, Elmira Khalili\|Pasha, Sara\|Vandfaez, Narges Ebrahimi\|Nazemalhosseini Mojarad, Ehsan\|Aghdaei, Hamid Asadzadeh\|Zali, Mohammad Reza
PMID:	24834285

1623.
Journal:	Chin Clin Oncol. 2013 Jun;2(2):17.
Title:	Adjuvant therapy of stage III colon cancer.
Author:	Sun, Weijing\|Haller, Daniel G
PMID:	25841497

1624.
Journal:	Scand J Pain. 2013 Jan 1;4(1):3-7.
Title:	Epithelial growth factor receptor (EGFR)-inhibition for relief of neuropathic pain-A case series.
Author:	Kersten, Christian\|Cameron, Marte Gronlie\|Mjaland, Svein
PMID:	29913887

1625.
Journal:	Pharmacogenomics J. 2014 Feb;14(1):14-9.
Title:	Role of immunoglobulin G fragment C receptor polymorphism-mediated antibody-dependant cellular cytotoxicity in colorectal cancer treated with cetuximab therapy.
Author:	Negri, F V\|Musolino, A\|Naldi, N\|Bortesi, B\|Missale, G\|Laccabue, D\|Zerbini, A\|Camisa, R\|Chernyschova, N\|Bisagni, G\|Loupakis, F\|Ruzzo, A\|Neri, T M\|Ardizzoni, A
PMID:	23296156

1626.
Journal:	J Oncol Pharm Pract. 2014 Feb;20(1):11-28.
Title:	Predictive and prognostic biomarkers with therapeutic targets in breast, colorectal, and non-small cell lung cancers: a systemic review of current development, evidence, and recommendation.
Author:	Chung, Clement\|Christianson, Matthew
PMID:	23493335

1627.
Journal:	Invest New Drugs. 2014 Feb;32(1):113-22.
Title:	Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients.
Author:	Rubinson, Douglas A\|Hochster, Howard S\|Ryan, David P\|Wolpin, Brian M\|McCleary, Nadine Jackson\|Abrams, Thomas A\|Chan, Jennifer A\|Iqbal, Syma\|Lenz, Heinz J\|Lim, Dean\|Rose, Jeffrey\|Bekaii-Saab, Tanios\|Chen, Helen X\|Fuchs, Charles S\|Ng, Kimmie
PMID:	23568716

1628.
Journal:	Target Oncol. 2014 Jun;9(2):171-5.
Title:	Is availability of anti-EGFR therapy for the colorectal adenocarcinomas showing fascin expression limited?
Author:	Kocer, Nazim Emrah\|Kayaselcuk, Fazilet
PMID:	23588415

1629.
Journal:	Oncogene. 2014 Apr 17;33(16):2123-33.
Title:	Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.
Author:	Cardoso, A P\|Pinto, M L\|Pinto, A T\|Oliveira, M I\|Pinto, M T\|Goncalves, R\|Relvas, J B\|Figueiredo, C\|Seruca, R\|Mantovani, A\|Mareel, M\|Barbosa, M A\|Oliveira, M J
PMID:	23644655

1630.
Journal:	Int J Cancer. 2014 May 1;134(9):2019-29.
Title:	The molecular rationale of Src inhibition in colorectal carcinomas.
Author:	Gargalionis, Antonios N\|Karamouzis, Michalis V\|Papavassiliou, Athanasios G
PMID:	23733480

1631.
Journal:	Invest New Drugs. 2014 Feb;32(1):160-70.
Title:	Phase 1 dose-escalation, pharmacokinetic, and cerebrospinal fluid distribution study of TAK-285, an investigational inhibitor of EGFR and HER2.
Author:	LoRusso, Patricia\|Venkatakrishnan, Karthik\|Chiorean, E Gabriela\|Noe, Dennis\|Wu, Jing-Tao\|Sankoh, Serap\|Corvez, Maria\|Sausville, Edward A
PMID:	23817974

1632.
Journal:	Int J Cancer. 2014 Jun 1;134(11):2513-22.
Title:	Tumor markers in colorectal cancer, gastric cancer and gastrointestinal stromal cancers: European group on tumor markers 2014 guidelines update.
Author:	Duffy, M J\|Lamerz, R\|Haglund, C\|Nicolini, A\|Kalousova, M\|Holubec, L\|Sturgeon, C
PMID:	23852704

1633.
Journal:	Clin Exp Metastasis. 2014 Jan;31(1):1-14.
Title:	Tumour growth stimulation following partial hepatectomy in mice is associated with increased upregulation of c-Met.
Author:	Harun, Nadia\|Costa, Patricia\|Christophi, C
PMID:	23900501

1634.
Journal:	Int J Colorectal Dis. 2014 Jan;29(1):31-41.
Title:	Gefitinib enhances the effects of combined radiotherapy and 5-fluorouracil in a colorectal cancer cell line.
Author:	Palumbo, Isabella\|Piattoni, Simonetta\|Valentini, Vincenzo\|Marini, Valeria\|Contavalli, Paola\|Calzuola, Monica\|Vecchio, Fabio Maria\|Cecchini, Debora\|Falzetti, Franca\|Aristei, Cynthia
PMID:	23917393

1635.
Journal:	Dig Liver Dis. 2014 Feb;46(2):105-12.
Title:	Options for metastatic colorectal cancer beyond the second line of treatment.
Author:	Foubert, Fanny\|Matysiak-Budnik, Tamara\|Touchefeu, Yann
PMID:	23954144

1636.
Journal:	Pharmacogenomics J. 2014 Jun;14(3):256-62.
Title:	Intergenic polymorphisms in the amphiregulin gene region as biomarkers in metastatic colorectal cancer patients treated with anti-EGFR plus irinotecan.
Author:	Sebio, A\|Paez, D\|Salazar, J\|Berenguer-Llergo, A\|Pare-Brunet, L\|Lasa, A\|Del Rio, E\|Tobena, M\|Martin-Richard, M\|Baiget, M\|Barnadas, A
PMID:	23959273

1637.
Journal:	J Clin Pathol. 2014 Jan;67(1):1-9.
Title:	KRAS testing in metastatic colorectal carcinoma: challenges, controversies, breakthroughs and beyond.
Author:	Malapelle, Umberto\|Carlomagno, Chiara\|de Luca, Caterina\|Bellevicine, Claudio\|Troncone, Giancarlo
PMID:	24022727

1638.
Journal:	Cancer Lett. 2014 Feb 1;343(1):1-5.
Title:	Clinical relevance of KRAS mutations in codon 13: Where are we?
Author:	Er, Tze-Kiong\|Chen, Chih-Chieh\|Bujanda, Luis\|Herreros-Villanueva, Marta
PMID:	24051306

1639.
Journal:	J Clin Pathol. 2014 Mar;67(3):198-203.
Title:	miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor.
Author:	Pichler, Martin\|Winter, Elke\|Ress, Anna Lena\|Bauernhofer, Thomas\|Gerger, Armin\|Kiesslich, Tobias\|Lax, Sigurd\|Samonigg, Hellmut\|Hoefler, Gerald
PMID:	24098024

1640.
Journal:	J Magn Reson Imaging. 2014 Jun;39(6):1436-42.
Title:	Rectal cancer: dynamic contrast-enhanced MRI correlates with lymph node status and epidermal growth factor receptor expression.
Author:	Lollert, Andre\|Junginger, Theodor\|Schimanski, Carl Christoph\|Biesterfeld, Stefan\|Gockel, Ines\|Duber, Christoph\|Oberholzer, Katja
PMID:	24127411

1641.
Journal:	Int J Cancer. 2014 May 1;134(9):2146-55.
Title:	KRAS mutation confers resistance to antibody-dependent cellular cytotoxicity of cetuximab against human colorectal cancer cells.
Author:	Nakadate, Yusuke\|Kodera, Yasuo\|Kitamura, Yuka\|Shirasawa, Senji\|Tachibana, Taro\|Tamura, Tomohide\|Koizumi, Fumiaki
PMID:	24136682

1642.
Journal:	Oncogene. 2014 Sep 4;33(36):4531-6.
Title:	Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling.
Author:	Kamekura, R\|Kolegraff, K N\|Nava, P\|Hilgarth, R S\|Feng, M\|Parkos, C A\|Nusrat, A
PMID:	24166502

1643.
Journal:	Clin Cancer Res. 2014 Jan 1;20(1):265-72.
Title:	Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.
Author:	Guinney, Justin\|Ferte, Charles\|Dry, Jonathan\|McEwen, Robert\|Manceau, Gilles\|Kao, K J\|Chang, Kai-Ming\|Bendtsen, Claus\|Hudson, Kevin\|Huang, Erich\|Dougherty, Brian\|Ducreux, Michel\|Soria, Jean-Charles\|Friend, Stephen\|Derry, Jonathan\|Laurent-Puig, Pierre
PMID:	24170544

1644.
Journal:	Clin Cancer Res. 2014 Jan 1;20(1):164-75.
Title:	AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer.
Author:	Dunne, Philip D\|McArt, Darragh G\|Blayney, Jaine K\|Kalimutho, Murugan\|Greer, Samanda\|Wang, Tingting\|Srivastava, Supriya\|Ong, Chee Wee\|Arthur, Ken\|Loughrey, Maurice\|Redmond, Keara\|Longley, Daniel B\|Salto-Tellez, Manuel\|Johnston, Patrick G\|Van Schaeybroeck,
PMID:	24170546

1645.
Journal:	Mol Cancer Res. 2014 Feb;12(2):228-38.
Title:	The metalloprotease ADAMTS8 displays antitumor properties through antagonizing EGFR-MEK-ERK signaling and is silenced in carcinomas by CpG methylation.
Author:	Choi, Gigi C G\|Li, Jisheng\|Wang, Yajun\|Li, Lili\|Zhong, Lan\|Ma, Brigette\|Su, Xianwei\|Ying, Jianming\|Xiang, Tingxiu\|Rha, Sun Young\|Yu, Jun\|Sung, Joseph J Y\|Tsao, Sai Wah\|Chan, Anthony T C\|Tao, Qian
PMID:	24184540

1646.
Journal:	Neoplasma. 2014;61(1):1-8.
Title:	The role of tumor markers and biomarkers in colorectal cancer.
Author:	Lech, G\|Slotwinski, R\|Krasnodebski, I W
PMID:	24195503

1647.
Journal:	Int J Biol Markers. 2014 Mar 24;29(1):e55-61.
Title:	A PNA-mediated clamping PCR for routine detection of KRAS mutations in colorectal carcinoma.
Author:	Messa, Francesca\|Tonissi, Federica\|Millo, Enrico\|Bracco, Enrico\|Ungari, Silvana\|Lattanzio, Laura\|Merlano, Marco\|Damonte, Gianluca\|Lo Nigro, Cristiana
PMID:	24242294

1648.
Journal:	Eur J Cancer. 2014 Feb;50(3):496-505.
Title:	Open-label, multicentre expansion cohort to evaluate imgatuzumab in pre-treated patients with KRAS-mutant advanced colorectal carcinoma.
Author:	Delord, Jean-Pierre\|Tabernero, Josep\|Garcia-Carbonero, Rocio\|Cervantes, Andres\|Gomez-Roca, Carlos\|Berge, Yann\|Capdevila, Jaume\|Paz-Ares, Luis\|Roda, Desamparados\|Delmar, Paul\|Oppenheim, David\|Brossard, Sophia Soehrman\|Farzaneh, Farzin\|Manenti, Luigi\|Passio
PMID:	24262587

1649.
Journal:	Pharmacol Res. 2014 Jan;79:34-74.
Title:	The ErbB/HER family of protein-tyrosine kinases and cancer.
Author:	Roskoski, Robert Jr
PMID:	24269963

1650.
Journal:	Ann Surg Oncol. 2014 Mar;21(3):946-54.
Title:	EGFR, BRAF and KRAS status in patients undergoing pulmonary metastasectomy from primary colorectal carcinoma: a prospective follow-up study.
Author:	Schweiger, Thomas\|Hegedus, Balazs\|Nikolowsky, Christoph\|Hegedus, Zita\|Szirtes, Ildiko\|Mair, Roland\|Birner, Peter\|Dome, Balazs\|Lang, Gyorgy\|Klepetko, Walter\|Ankersmit, Hendrik Jan\|Hoetzenecker, Konrad
PMID:	24281417

1651.
Journal:	Curr Oncol Rep. 2014;16(1):363.
Title:	Palliative treatment of metastatic colorectal cancer: what is the optimal approach?
Author:	Strickler, John H\|Hurwitz, Herbert I
PMID:	24293074

1652.
Journal:	Lung Cancer. 2014 Feb;83(2):163-7.
Title:	KRAS mutations in non-small-cell lung cancer and colorectal cancer: implications for EGFR-targeted therapies.
Author:	Maus, M K H\|Grimminger, P P\|Mack, P C\|Astrow, S H\|Stephens, C\|Zeger, G\|Hsiang, J\|Brabender, J\|Friedrich, M\|Alakus, H\|Holscher, A H\|Lara, P\|Danenberg, K D\|Lenz, H J\|Gandara, D R
PMID:	24331409

1653.
Journal:	Br J Cancer. 2014 Feb 4;110(3):648-55.
Title:	Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer.
Author:	Jonker, D J\|Karapetis, C S\|Harbison, C\|O'Callaghan, C J\|Tu, D\|Simes, R J\|Malone, D P\|Langer, C\|Tebbutt, N\|Price, T J\|Shapiro, J\|Siu, L L\|Wong, R P W\|Bjarnason, G\|Moore, M J\|Zalcberg, J R\|Khambata-Ford, S
PMID:	24335920

1654.
Journal:	Cancer Biol Ther. 2014 Mar 1;15(3):266-70.
Title:	Increase in antibody-dependent cellular cytotoxicity (ADCC) in a patient with advanced colorectal carcinoma carrying a KRAS mutation under lenalidomide therapy.
Author:	Gamerith, Gabriele\|Auer, Thomas\|Amann, Arno\|Putzer, Daniel\|Schenk, Bettina\|Kircher, Brigitte\|Hilbe, Wolfgang\|Zwierzina, Heinz\|Loeffler-Ragg, Judith
PMID:	24351336

1655.
Journal:	Mol Biol Rep. 2014 Mar;41(3):1291-8.
Title:	Effect of BRAF V600E mutation on tumor response of anti-EGFR monoclonal antibodies for first-line metastatic colorectal cancer treatment: a meta-analysis of randomized studies.
Author:	Cui, Dandan\|Cao, Dan\|Yang, Yu\|Qiu, Meng\|Huang, Ying\|Yi, Cheng
PMID:	24390240

1656.
Journal:	Anticancer Res. 2014 Jan;34(1):423-34.
Title:	Targeted agents and oxaliplatin-containing regimens for the treatment of colon cancer.
Author:	Bonetti, Andrea\|Giuliani, Jacopo\|Muggia, Franco
PMID:	24403498

1657.
Journal:	Gan To Kagaku Ryoho. 2014 Jan;41(1):1-6.
Title:	[Clinical application of next-generation sequencing technologies to achieve cancer precision medicine].
Author:	Tsuchihara, Katsuya
PMID:	24423944

1658.
Journal:	Cancer Biol Ther. 2014;15(2):147-8.
Title:	When to screen and not to screen.
Author:	Cruickshanks, Nichola
PMID:	24424112

1659.
Journal:	Analyst. 2014 Mar 7;139(5):1155-61.
Title:	Label-free imaging of drug distribution and metabolism in colon cancer cells by Raman microscopy.
Author:	El-Mashtoly, Samir F\|Petersen, Dennis\|Yosef, Hesham K\|Mosig, Axel\|Reinacher-Schick, Anke\|Kotting, Carsten\|Gerwert, Klaus
PMID:	24427772

1660.
Journal:	Int J Clin Oncol. 2014 Apr;19(2):211-9.
Title:	Is biomarker research advancing in the era of personalized medicine for head and neck cancer?
Author:	Yokota, Tomoya
PMID:	24442754

1661.
Journal:	J Labelled Comp Radiopharm. 2014 Jan;57(1):25-35.
Title:	Preparation of clinical-grade (89) Zr-panitumumab as a positron emission tomography biomarker for evaluating epidermal growth factor receptor-targeted therapy.
Author:	Wei, Ling\|Shi, Jianfeng\|Afari, George\|Bhattacharyya, Sibaprasad
PMID:	24448743

1662.
Journal:	PLoS One. 2014 Jan 15;9(1):e84597.
Title:	MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance.
Author:	Lee, Chang Gong\|McCarthy, Susan\|Gruidl, Mike\|Timme, Cindy\|Yeatman, Timothy J
PMID:	24454732

1663.
Journal:	Digestion. 2014;89(1):18-23.
Title:	Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer.
Author:	Okada, Yasuyuki\|Miyamoto, Hiroshi\|Goji, Takahiro\|Takayama, Tetsuji
PMID:	24458108

1664.
Journal:	Curr Cancer Drug Targets. 2014;14(2):217-24.
Title:	Cetuximab inhibits gastric cancer growth in vivo, independent of KRAS status.
Author:	Shi, Min\|Shi, Hailong\|Ji, Jun\|Cai, Qu\|Chen, Xuehua\|Yu, Yingyan\|Liu, Bingya\|Zhu, Zhenggang\|Zhang, Jun
PMID:	24467518

1665.
Journal:	Br J Cancer. 2014 Mar 4;110(5):1221-7.
Title:	Glyco-engineered anti-EGFR mAb elicits ADCC by NK cells from colorectal cancer patients irrespective of chemotherapy.
Author:	Oppenheim, D E\|Spreafico, R\|Etuk, A\|Malone, D\|Amofah, E\|Pena-Murillo, C\|Murray, T\|McLaughlin, L\|Choi, B S\|Allan, S\|Belousov, A\|Passioukov, A\|Gerdes, C\|Umana, P\|Farzaneh, F\|Ross, P
PMID:	24496456

1666.
Journal:	Cancer Chemother Pharmacol. 2014 Apr;73(4):749-57.
Title:	Overexpression of MET is a new predictive marker for anti-EGFR therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Watanabe, Takashi\|Sugiyama, Masanori
PMID:	24500024

1667.
Journal:	Am J Surg Pathol. 2014 Jul;38(7):910-20.
Title:	SMARCB1 (INI1)-negative rhabdoid carcinomas of the gastrointestinal tract: clinicopathologic and molecular study of a highly aggressive variant with literature review.
Author:	Agaimy, Abbas\|Rau, Tilman T\|Hartmann, Arndt\|Stoehr, Robert
PMID:	24503755

1668.
Journal:	Anticancer Res. 2014 Feb;34(2):613-21.
Title:	Melting curve analysis for mutations of EGFR and KRAS.
Author:	Furugaki, Koh\|Yasuno, Hideyuki\|Iwai, Toshiki\|Moriya, Yoichiro\|Harada, Naoki\|Fujimoto-Ouchi, Kaori
PMID:	24510990

1669.
Journal:	Gut Liver. 2014 Jan;8(1):13-23.
Title:	The expression of multiple proteins as prognostic factors in colorectal cancer: cathepsin D, p53, COX-2, epidermal growth factor receptor, C-erbB-2, and Ki-67.
Author:	Shin, Il Yong\|Sung, Na Young\|Lee, Youn Soo\|Kwon, Taek Soo\|Si, Yoon\|Lee, Yoon Suk\|Oh, Seong Taek\|Lee, In Kyu
PMID:	24516696

1670.
Journal:	Cancer Res. 2014 Apr 1;74(7):2062-72.
Title:	Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-alpha: impact on gastrointestinal cancers driven by secondary bile acids.
Author:	Nagathihalli, Nagaraj S\|Beesetty, Yugandhar\|Lee, Wooin\|Washington, M Kay\|Chen, Xi\|Lockhart, A Craig\|Merchant, Nipun B
PMID:	24520077

1671.
Journal:	Cancer Res Treat. 2014 Jan;46(1):48-54.
Title:	Dose KRAS Mutation Status Affect on the Effect of VEGF Therapy in Metastatic Colon Cancer Patients?
Author:	Kim, Seung Tae\|Park, Kyong Hwa\|Shin, Sang Won\|Kim, Yeul Hong
PMID:	24520223

1672.
Journal:	Curr Oncol. 2014 Feb;21(1):e151-4.
Title:	Anticancer activity of combination targeted therapy using cetuximab plus vemurafenib for refractory BRAF (V600E)-mutant metastatic colorectal carcinoma.
Author:	Connolly, K\|Brungs, D\|Szeto, E\|Epstein, R J
PMID:	24523613

1673.
Journal:	Clin Chim Acta. 2014 Apr 20;431:211-20.
Title:	KRAS mutations: analytical considerations.
Author:	Herreros-Villanueva, Marta\|Chen, Chih-Chieh\|Yuan, Shyng-Shiou F\|Liu, Ta-Chih\|Er, Tze-Kiong
PMID:	24534449

1674.
Journal:	Sci Transl Med. 2014 Feb 19;6(224):224ra26.
Title:	Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer.
Author:	Misale, Sandra\|Arena, Sabrina\|Lamba, Simona\|Siravegna, Giulia\|Lallo, Alice\|Hobor, Sebastijan\|Russo, Mariangela\|Buscarino, Michela\|Lazzari, Luca\|Sartore-Bianchi, Andrea\|Bencardino, Katia\|Amatu, Alessio\|Lauricella, Calogero\|Valtorta, Emanuele\|Siena, Salvato
PMID:	24553387

1675.
Journal:	Cancer Biol Ther. 2014 May;15(5):623-32.
Title:	Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity.
Author:	Ung, Nelson\|Putoczki, Tracy L\|Stylli, Stanley S\|Ng, Irvin\|Mariadason, John M\|Chan, Timothy A\|Zhu, Hong-Jian\|Luwor, Rodney B
PMID:	24556630

1676.
Journal:	Gastrointest Cancer Res. 2014 Jan;7(1):23-6.
Title:	KRAS G13D Mutation and Sensitivity to Cetuximab or Panitumumab in a Colorectal Cancer Cell Line Model.
Author:	Kumar, Shalini Sree\|Price, Timothy J\|Mohyieldin, Omar\|Borg, Matthew\|Townsend, Amanda\|Hardingham, Jennifer E
PMID:	24558511

1677.
Journal:	Pathol Res Pract. 2014 May;210(5):274-8.
Title:	EGFR, KRAS, BRAF-mutations and microsatellite instability are absent in goblet cell carcinoids of the appendix.
Author:	Dimmler, Arno\|Geddert, Helene\|Faller, Gerhard
PMID:	24560515

1678.
Journal:	BMC Cancer. 2014 Feb 25;14:128.
Title:	Can we accurately report PTEN status in advanced colorectal cancer?
Author:	Hocking, Christopher\|Hardingham, Jennifer E\|Broadbridge, Vy\|Wrin, Joe\|Townsend, Amanda R\|Tebbutt, Niall\|Cooper, John\|Ruszkiewicz, Andrew\|Lee, Chee\|Price, Timothy J
PMID:	24564252

1679.
Journal:	Oncol Rep. 2014 Apr;31(4):1811-7.
Title:	Adenomatous polyposis coli determines sensitivity to the EGFR tyrosine kinase inhibitor gefitinib in colorectal cancer cells.
Author:	Zhang, Yining\|Xiao, Qinghuan\|Zhang, Huijing\|Sun, Xuren\|Ge, Huijuan\|Liu, Xiaoming\|Guan, Lin\|Sun, Mingjun
PMID:	24573033

1680.
Journal:	Eur J Cancer. 2014 May;50(8):1430-6.
Title:	RAS mutations and cetuximab in locally advanced rectal cancer: results of the EXPERT-C trial.
Author:	Sclafani, F\|Gonzalez, D\|Cunningham, D\|Hulkki Wilson, S\|Peckitt, C\|Giralt, J\|Glimelius, B\|Rosello Keranen, S\|Wotherspoon, A\|Brown, G\|Tait, D\|Oates, J\|Chau, I
PMID:	24582914

1681.
Journal:	J Med Chem. 2014 Mar 27;57(6):2692-703.
Title:	Identification and optimization of new dual inhibitors of B-Raf and epidermal growth factor receptor kinases for overcoming resistance against vemurafenib.
Author:	Cheng, Huimin\|Chang, Yu\|Zhang, Lianwen\|Luo, Jinfeng\|Tu, Zhengchao\|Lu, Xiaoyun\|Zhang, Qingwen\|Lu, Jibu\|Ren, Xiaomei\|Ding, Ke
PMID:	24588073

1682.
Journal:	Exp Mol Pathol. 2014 Apr;96(2):257-60.
Title:	KRAS insertions in colorectal cancer: what do we know about unusual KRAS mutations?
Author:	de Macedo, Mariana Petaccia\|de Lima, Luiz Guilherme Cernaglia Aureliano\|Begnami, Maria Dirlei Ferreira de Souza\|de Melo, Fernanda Machado\|Andrade, Louise D Brot\|Lisboa, Bianca Cristina Garcia\|Soares, Luisa Martelli\|Soares, Fernando Augusto\|Carraro, Dirce
PMID:	24594115

1683.
Journal:	Virchows Arch. 2014 May;464(5):575-81.
Title:	Mutation status of somatic EGFR and KRAS genes in Chinese patients with prostate cancer (PCa).
Author:	Fu, Meng\|Zhang, Wei\|Shan, Ling\|Song, Jian\|Shang, Donghao\|Ying, Jianming\|Zhao, Jimao
PMID:	24595526

1684.
Journal:	J Cancer Res Clin Oncol. 2014 May;140(5):737-48.
Title:	EGFR gene gain and PTEN protein expression are favorable prognostic factors in patients with KRAS wild-type metastatic colorectal cancer treated with cetuximab.
Author:	Razis, Evangelia\|Pentheroudakis, George\|Rigakos, George\|Bobos, Mattheos\|Kouvatseas, George\|Tzaida, Olympia\|Makatsoris, Thomas\|Papakostas, Pavlos\|Bai, Maria\|Goussia, Anna\|Samantas, Epaminontas\|Papamichael, Demetrios\|Romanidou, Ourania\|Efstratiou, Ioannis\|T
PMID:	24595598

1685.
Journal:	Nihon Rinsho. 2014 Jan;72(1):29-34.
Title:	[Perspective of personalized (precise) cancer therapy based on predictive biomarkers].
Author:	Osera, Shozo\|Yoshino, Takayuki
PMID:	24597345

1686.
Journal:	Nihon Rinsho. 2014 Jan;72(1):63-70.
Title:	[The brand new trend of colorectal carcinoma pathology].
Author:	Tomita, Shigeki\|Yamauchi, Mayuko\|Ichikawa, Kazuhito\|Mitomi, Hiroyuki\|Fujimori, Takahiro
PMID:	24597350

1687.
Journal:	Nihon Rinsho. 2014 Jan;72(1):114-9.
Title:	[Use of antibodies for colorectal cancer chemotherapy].
Author:	Kanemitsu, Kiyonori\|Kakeji, Yoshihiro
PMID:	24597358

1688.
Journal:	PLoS One. 2014 Mar 7;9(3):e91139.
Title:	Co-expression of HER family members in patients with Dukes' C and D colon cancer and their impacts on patient prognosis and survival.
Author:	Khelwatty, Said Abdullah\|Essapen, Sharadah\|Bagwan, Izhar\|Green, Margaret\|Seddon, Alan Michael\|Modjtahedi, Helmout
PMID:	24609222

1689.
Journal:	PLoS One. 2014 Mar 11;9(3):e90997.
Title:	Cytohesins/ARNO: the function in colorectal cancer cells.
Author:	Pan, Tao\|Sun, Junfeng\|Hu, Jiyi\|Hu, Yiwang\|Zhou, Jun\|Chen, Zhigang\|Xu, Dong\|Xu, Wenhong\|Zheng, Shu\|Zhang, Suzhan
PMID:	24618737

1690.
Journal:	BMC Genomics. 2014 Mar 13;15:190.
Title:	Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author:	Castle, John C\|Loewer, Martin\|Boegel, Sebastian\|de Graaf, Jos\|Bender, Christian\|Tadmor, Arbel D\|Boisguerin, Valesca\|Bukur, Thomas\|Sorn, Patrick\|Paret, Claudia\|Diken, Mustafa\|Kreiter, Sebastian\|Tureci, Ozlem\|Sahin, Ugur
PMID:	24621249

1691.
Journal:	Front Oncol. 2014 Mar 3;4:35.
Title:	PIK3CA in Colorectal Cancer.
Author:	Cathomas, Gieri
PMID:	24624362

1692.
Journal:	Oncol Rep. 2014 May;31(5):2115-22.
Title:	Cetuximab-mediated ADCC activity is correlated with the cell surface expression level of EGFR but not with the KRAS/BRAF mutational status in colorectal cancer.
Author:	Seo, Yuki\|Ishii, Yoshiyuki\|Ochiai, Hiroki\|Fukuda, Kazumasa\|Akimoto, Shingo\|Hayashida, Tetsu\|Okabayashi, Koji\|Tsuruta, Masashi\|Hasegawa, Hirotoshi\|Kitagawa, Yuko
PMID:	24626880

1693.
Journal:	Mol Cancer Ther. 2014 May;13(5):1345-55.
Title:	ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models.
Author:	Zhang, Li\|Castanaro, Carla\|Luan, Bo\|Yang, Katie\|Fan, Liangfen\|Fairhurst, Jeanette L\|Rafique, Ashique\|Potocky, Terra B\|Shan, Jing\|Delfino, Frank J\|Shi, Ergang\|Huang, Tammy\|Martin, Joel H\|Chen, Gang\|Macdonald, Douglas\|Rudge, John S\|Thurston, Gavin\|Daly, Chr
PMID:	24634416

1694.
Journal:	Pathobiology. 2014;81(3):133-7.
Title:	Analysis of KRAS mutations in cases of metastatic colorectal cancer at a single institution in Tochigi, Japan.
Author:	Saito, Natsuko\|Tomita, Shigeki\|Ichikawa, Kazuhito\|Mitomi, Hiroyuki\|Imura, Johji\|Fujimori, Takahiro
PMID:	24642668

1695.
Journal:	Naunyn Schmiedebergs Arch Pharmacol. 2014 Jun;387(6):505-21.
Title:	A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer.
Author:	Modjtahedi, Helmout\|Cho, Byoung Chul\|Michel, Martin C\|Solca, Flavio
PMID:	24643470

1696.
Journal:	Mol Cancer Res. 2014 Jun;12(6):823-9.
Title:	HD chromoendoscopy coupled with DNA mass spectrometry profiling identifies somatic mutations in microdissected human proximal aberrant crypt foci.
Author:	Drew, David A\|Devers, Thomas J\|O'Brien, Michael J\|Horelik, Nicole A\|Levine, Joel\|Rosenberg, Daniel W
PMID:	24651453

1697.
Journal:	Int J Cancer. 2014 Nov 1;135(9):2215-22.
Title:	Changes in mutational status during third-line treatment for metastatic colorectal cancer--results of consecutive measurement of cell free DNA, KRAS and BRAF in the plasma.
Author:	Spindler, Karen-Lise Garm\|Pallisgaard, Niels\|Andersen, Rikke Fredslund\|Jakobsen, Anders
PMID:	24659028

1698.
Journal:	Mol Diagn Ther. 2014 Aug;18(4):459-68.
Title:	Highly sensitive KRAS mutation detection from formalin-fixed paraffin-embedded biopsies and circulating tumour cells using wild-type blocking polymerase chain reaction and Sanger sequencing.
Author:	Huang, Meggie Mo Chao\|Leong, Sai Mun\|Chua, Hui Wen\|Tucker, Steven\|Cheong, Wai Chye\|Chiu, Lily\|Li, Mo-Huang\|Koay, Evelyn Siew-Chuan
PMID:	24664550

1699.
Journal:	Tumour Biol. 2014 Jul;35(7):6397-404.
Title:	VPAC1 overexpression is associated with poor differentiation in colon cancer.
Author:	Liu, Shaohua\|Zeng, Yunjie\|Li, Yunhua\|Guo, Wenying\|Liu, Jiali\|Ouyang, Nengtai
PMID:	24671823

1700.
Journal:	PLoS Genet. 2014 Mar 27;10(3):e1004271.
Title:	Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
Author:	Mohan, Sumitra\|Heitzer, Ellen\|Ulz, Peter\|Lafer, Ingrid\|Lax, Sigurd\|Auer, Martina\|Pichler, Martin\|Gerger, Armin\|Eisner, Florian\|Hoefler, Gerald\|Bauernhofer, Thomas\|Geigl, Jochen B\|Speicher, Michael R
PMID:	24676216

1701.
Journal:	Oncol Rep. 2014 May;31(5):2393-8.
Title:	Transphosphorylation of EGFR at Y845 plays an important role in its autophosphorylation and kinase activity.
Author:	Song, Hui\|Huang, Lei\|Zhang, Ming\|Wang, Xiuwei\|Song, Shuang\|Yang, Lin
PMID:	24677053

1702.
Journal:	Oncologist. 2014 Apr;19(4):356-7.
Title:	Mitomycin C and high-dose 5-fluorouracil with folinic acid as a therapeutic option for heavily pretreated patients with metastatic colorectal cancer: prospective phase II trial.
Author:	Stec, Rafal\|Bodnar, Lubomir\|Smoter, Marta\|Korniluk, Jan\|Kuchar, Agata\|Mlot, Beata\|Szczylik, Cezary
PMID:	24682464

1703.
Journal:	Cell Rep. 2014 Apr 10;7(1):86-93.
Title:	Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.
Author:	Sun, Chong\|Hobor, Sebastijan\|Bertotti, Andrea\|Zecchin, Davide\|Huang, Sidong\|Galimi, Francesco\|Cottino, Francesca\|Prahallad, Anirudh\|Grernrum, Wipawadee\|Tzani, Anna\|Schlicker, Andreas\|Wessels, Lodewyk F A\|Smit, Egbert F\|Thunnissen, Erik\|Halonen, Pasi\|Lieft
PMID:	24685132

1704.
Journal:	Clin Chim Acta. 2014 Jun 10;433:284-9.
Title:	Comparison of KRAS mutation analysis of primary tumors and matched circulating cell-free DNA in plasmas of patients with colorectal cancer.
Author:	Kuo, Yung-Bin\|Chen, Jinn-Shiun\|Fan, Chung-Wei\|Li, Yi-Shuan\|Chan, Err-Cheng
PMID:	24685572

1705.
Journal:	PLoS One. 2014 Apr 1;9(4):e92147.
Title:	Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status.
Author:	Pietrantonio, Filippo\|Maggi, Claudia\|Di Bartolomeo, Maria\|Facciorusso, Maria Grazia\|Perrone, Federica\|Testi, Adele\|Iacovelli, Roberto\|Miceli, Rosalba\|Bossi, Ilaria\|Leone, Giorgia\|Milione, Massimo\|Pelosi, Giuseppe\|de Braud, Filippo
PMID:	24691006

1706.
Journal:	Anticancer Res. 2014 Apr;34(4):1793-800.
Title:	COX2 inhibitor NS398 reduces HT-29 cell invasiveness by modulating signaling pathways mediated by EGFR and HIF1-alpha.
Author:	Bocca, Claudia\|Bozzo, Francesca\|Miglietta, Antonella
PMID:	24692712

1707.
Journal:	Int J Clin Exp Pathol. 2014 Feb 15;7(3):1266-74. eCollection 2014.
Title:	Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases.
Author:	Wang, Cai-Xia\|Liu, Biao\|Wang, Yan-Fen\|Zhang, Ru-Song\|Yu, Bo\|Lu, Zhen-Feng\|Shi, Qun-Li\|Zhou, Xiao-Jun
PMID:	24696747

1708.
Journal:	Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title:	The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author:	Abdul-Jalil, Khairun I\|Sheehan, Katherine M\|Toomey, Sinead\|Schmid, Jasmin\|Prehn, Jochen\|O'Grady, Anthony\|Cummins, Robert\|O'Neill, Brian\|McNamara, Deborah A\|Deasy, Joseph\|Breathnach, Oscar\|Grogan, Liam\|Rogers, Ailin\|Doherty, Glen\|Winter, Des\|Ryan, John\|El-
PMID:	24700299

1709.
Journal:	Lancet Oncol. 2014 May;15(6):549-50.
Title:	Exploring better strategies for EGFR antibodies in colon cancer.
Author:	Cervantes, Andres
PMID:	24703530

1710.
Journal:	BMC Cancer. 2014 Apr 4;14:241.
Title:	P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer.
Author:	Sim, Sung Hoon\|Kang, Mi-Hyun\|Kim, Yu Jung\|Lee, Keun-Wook\|Kim, Duck-Woo\|Kang, Sung-Bum\|Eom, Keun-Yong\|Kim, Jae-Sung\|Lee, Hye Seung\|Kim, Jee Hyun
PMID:	24708484

1711.
Journal:	Int J Mol Sci. 2014 Apr 4;15(4):5838-51.
Title:	Cetuximab-induced MET activation acts as a novel resistance mechanism in colon cancer cells.
Author:	Song, Na\|Liu, Shizhou\|Zhang, Jingdong\|Liu, Jing\|Xu, Ling\|Liu, Yunpeng\|Qu, Xiujuan
PMID:	24714091

1712.
Journal:	Mol Pharm. 2014 Nov 3;11(11):3980-7.
Title:	Comparison of conjugation strategies of cross-bridged macrocyclic chelators with cetuximab for copper-64 radiolabeling and PET imaging of EGFR in colorectal tumor-bearing mice.
Author:	Zeng, Dexing\|Guo, Yunjun\|White, Alexander G\|Cai, Zhengxin\|Modi, Jalpa\|Ferdani, Riccardo\|Anderson, Carolyn J
PMID:	24720806

1713.
Journal:	Cancer Lett. 2014 Jul 10;349(1):51-60.
Title:	Resistance to irinotecan (CPT-11) activates epidermal growth factor receptor/nuclear factor kappa B and increases cellular metastasis and autophagy in LoVo colon cancer cells.
Author:	Chen, Ming-Cheng\|Lee, Nien-Hung\|Ho, Tsung-Jung\|Hsu, Hsi-Hsien\|Kuo, Chia-Hua\|Kuo, Wei-Wen\|Lin, Yueh-Min\|Tsai, Fuu-Jen\|Tsai, Chang-Hai\|Huang, Chih-Yang
PMID:	24726344

1714.
Journal:	Prog Tumor Res. 2014;41:36-50.
Title:	Successes and limitations of targeted cancer therapy in colon cancer.
Author:	Kohne, Claus-Henning
PMID:	24727985

1715.
Journal:	Biochim Biophys Acta. 2014 Sep;1842(9):1423-32.
Title:	MFAP3L activation promotes colorectal cancer cell invasion and metastasis.
Author:	Lou, Xiaomin\|Kang, Bin\|Zhang, Jun\|Hao, Chunyi\|Tian, Xiuyun\|Li, Wenmei\|Xu, Ningzhi\|Lu, Youyong\|Liu, Siqi
PMID:	24735981

1716.
Journal:	ScientificWorldJournal. 2014 Mar 4;2014:102541.
Title:	Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination.
Author:	Lustosa, Suzana Angelica Silva\|Viana, Luciano de Souza\|Affonso, Renato Jose Jr\|Silva, Sandra Regina Morini\|Denadai, Marcos Vinicius Araujo\|de Toledo, Silvia Regina Caminada\|Oliveira, Indhira Dias\|Matos, Delcio
PMID:	24737953

1717.
Journal:	Lancet Oncol. 2014 May;15(6):540-1.
Title:	Targeting EGFR in colorectal cancer: beyond KRAS exon 2.
Author:	Waddell, Tom
PMID:	24739895

1718.
Journal:	Methods Mol Biol. 2014;1160:189-214.
Title:	Clinical applications using digital PCR.
Author:	Bizouarn, Francisco
PMID:	24740231

1719.
Journal:	Rev Recent Clin Trials. 2014;9(1):8-12.
Title:	The Emerging Role of NRAS Mutations in Colorectal Cancer Patients Selected for Anti-EGFR Therapies.
Author:	Meriggi, Fausto\|Vermi, William\|Bertocchi, Paola\|Zaniboni, Alberto
PMID:	24758538

1720.
Journal:	PLoS One. 2014 Apr 23;9(4):e94621.
Title:	Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.
Author:	Sahlberg, Sara Haggblad\|Spiegelberg, Diana\|Glimelius, Bengt\|Stenerlow, Bo\|Nestor, Marika
PMID:	24760019

1721.
Journal:	Expert Opin Drug Saf. 2014 Jun;13(6):843-51.
Title:	Panitumumab safety for treating colorectal cancer.
Author:	Stremitzer, Stefan\|Sebio, Ana\|Stintzing, Sebastian\|Lenz, Heinz-Josef
PMID:	24766434

1722.
Journal:	PLoS One. 2014 Apr 25;9(4):e96420.
Title:	Real-time bidirectional pyrophosphorolysis-activated polymerization for quantitative detection of somatic mutations.
Author:	Song, Najie\|Zhong, Xueting\|Li, Qingge
PMID:	24769870

1723.
Journal:	Mol Cancer. 2014 Apr 29;13:95.
Title:	SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1.
Author:	Qu, Yingying\|Chen, Qin\|Lai, Xueping\|Zhu, Changhong\|Chen, Cheng\|Zhao, Xian\|Deng, Rong\|Xu, Ming\|Yuan, Haihua\|Wang, Yanli\|Yu, Jianxiu\|Huang, Jian
PMID:	24775912

1724.
Journal:	EMBO J. 2014 Jul 1;33(13):1474-91.
Title:	c-Src drives intestinal regeneration and transformation.
Author:	Cordero, Julia B\|Ridgway, Rachel A\|Valeri, Nicola\|Nixon, Colin\|Frame, Margaret C\|Muller, William J\|Vidal, Marcos\|Sansom, Owen J
PMID:	24788409

1725.
Journal:	PLoS One. 2014 May 1;9(5):e94977.
Title:	Does KRAS testing in metastatic colorectal cancer impact overall survival? A comparative effectiveness study in a population-based sample.
Author:	Feigelson, Heather Spencer\|Zeng, Chan\|Pawloski, Pamala A\|Onitilo, Adedayo A\|Richards, C Sue\|Johnson, Monique A\|Kauffman, Tia L\|Webster, Jennifer\|Nyirenda, Carsie\|Alexander, Gwen L\|Hwang, Clara\|Cross, Deanna\|McCarty, Catherine A\|Davis, Robert L\|Schwarzkopf
PMID:	24788807

1726.
Journal:	Biochim Biophys Acta. 2014 Aug;1840(8):2651-61.
Title:	EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules.
Author:	Ellina, Maria-Ioanna\|Bouris, Panagiotis\|Aletras, Alexios J\|Theocharis, Achilleas D\|Kletsas, Dimitris\|Karamanos, Nikos K
PMID:	24792576

1727.
Journal:	Angiogenesis. 2014 Oct;17(4):805-21.
Title:	The role of antiangiogenic agents in the treatment of patients with advanced colorectal cancer according to K-RAS status.
Author:	Garcia-Alfonso, Pilar\|Grande, Enrique\|Polo, Eduardo\|Afonso, Ruth\|Reina, Juan Jose\|Jorge, Monica\|Campos, Juan Manuel\|Martinez, Virginia\|Angeles, Cristina\|Montagut, Clara
PMID:	24793846

1728.
Journal:	Pathology. 2014 Jun;46(4):311-5.
Title:	BRAFV600E mutation analysis by immunohistochemistry in patients with thoracic metastases from colorectal cancer.
Author:	Ilie, Marius I\|Long-Mira, Elodie\|Hofman, Veronique\|Mouroux, Jerome\|Vignaud, Jean-Michel\|Gauchotte, Guillaume\|Begueret, Hugues\|Merlio, Jean-Philippe\|Emile, Jean-Francois\|Hebuterne, Xavier\|Hofman, Paul
PMID:	24798160

1729.
Journal:	Future Oncol. 2014 Apr;10(5):713-23.
Title:	Pyrosequencing evaluation of low-frequency KRAS mutant alleles for EGF receptor therapy selection in metastatic colorectal carcinoma.
Author:	Natalicchio, Maria Iole\|Improta, Giuseppina\|Zupa, Angela\|Cursio, Olga Elisabetta\|Stampone, Emanuela\|Possidente, Luciana\|Teresa Gerardi, Assunta Maria\|Vita, Giulia\|Martini, Maurizio\|Cassano, Alessandra\|Piccoli, Claudia\|Romito, Sante\|Aieta, Michele\|Antonett
PMID:	24799053

1730.
Journal:	Br J Cancer. 2014 May 27;110(11):2728-37.
Title:	Molecular patterns in deficient mismatch repair colorectal tumours: results from a French prospective multicentric biological and genetic study.
Author:	Etienne-Grimaldi, M-C\|Mahamat, A\|Chazal, M\|Laurent-Puig, P\|Olschwang, S\|Gaub, M-P\|Formento, J-L\|Formento, P\|Sudaka, A\|Boige, V\|Abderrahim-Ferkoune, A\|Benchimol, D\|Andre, T\|Houry, S\|Faucheron, J-L\|Letoublon, C\|Gilly, F-N\|Delpero, J-R\|Lasser, P\|Pradere, B\|P
PMID:	24800948

1731.
Journal:	Oncol Rep. 2014 Jul;32(1):121-30.
Title:	MMP-2/9-oriented combinations enhance antitumor efficacy of EGFR/HER2-targeting fusion proteins and gemcitabine.
Author:	Qin, Ye\|Liu, Xiu-Jun\|Li, Liang\|Liu, Xu-Jie\|Li, Yi\|Gao, Rui-Juan\|Shao, Rong-Guang\|Zhen, Yong-Su
PMID:	24807584

1732.
Journal:	J Mol Med (Berl). 2014 Jul;92(7):709-22.
Title:	Primary and acquired resistance to EGFR-targeted therapies in colorectal cancer: impact on future treatment strategies.
Author:	Leto, Simonetta M\|Trusolino, Livio
PMID:	24811491

1733.
Journal:	Clin Cancer Res. 2014 Jul 15;20(14):3775-86.
Title:	Primary and acquired resistance of colorectal cancer cells to anti-EGFR antibodies converge on MEK/ERK pathway activation and can be overcome by combined MEK/EGFR inhibition.
Author:	Troiani, Teresa\|Napolitano, Stefania\|Vitagliano, Donata\|Morgillo, Floriana\|Capasso, Anna\|Sforza, Vincenzo\|Nappi, Anna\|Ciardiello, Davide\|Ciardiello, Fortunato\|Martinelli, Erika
PMID:	24812410

1734.
Journal:	Asian Pac J Cancer Prev. 2014;15(7):3045-50.
Title:	Targeting EGFL7 expression through RNA interference suppresses renal cell carcinoma growth by inhibiting angiogenesis.
Author:	Xu, Han-Feng\|Chen, Lei\|Liu, Xian-Dong\|Zhan, Yun-Hong\|Zhang, Hui-Hui\|Li, Qing\|Wu, Bin
PMID:	24815445

1735.
Journal:	Dis Colon Rectum. 2014 May;57(5):592-601.
Title:	Can a biomarker-based scoring system predict pathologic complete response after preoperative chemoradiotherapy for rectal cancer?
Author:	Hur, Hyuk\|Kim, Nam Kyu\|Min, Byung Soh\|Baik, Seung Hyuk\|Lee, Kang Young\|Koom, Woong Sub\|Ahn, Joong Bae\|Kim, Hoguen
PMID:	24819099

1736.
Journal:	J Clin Invest. 2014 Jun;124(6):2668-82.
Title:	Targeting CD137 enhances the efficacy of cetuximab.
Author:	Kohrt, Holbrook E\|Colevas, A Dimitrios\|Houot, Roch\|Weiskopf, Kipp\|Goldstein, Matthew J\|Lund, Peder\|Mueller, Antonia\|Sagiv-Barfi, Idit\|Marabelle, Aurelien\|Lira, Ruth\|Troutner, Emily\|Richards, Lori\|Rajapaska, Amanda\|Hebb, Jonathan\|Chester, Cariad\|Waller, Er
PMID:	24837434

1737.
Journal:	Oncol Rep. 2014 Jul;32(1):57-64.
Title:	Impact of genetic profiles on the efficacy of anti-EGFR antibodies in metastatic colorectal cancer with KRAS mutation.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Sugiyama, Masanori\|Watanabe, Takashi
PMID:	24839940

1738.
Journal:	Expert Rev Mol Diagn. 2014 Jun;14(5):517-24.
Title:	A new generation of companion diagnostics: cobas BRAF, KRAS and EGFR mutation detection tests.
Author:	Angulo, Barbara\|Lopez-Rios, Fernando\|Gonzalez, David
PMID:	24844134

1739.
Journal:	Tumour Biol. 2014 Aug;35(8):8161-7.
Title:	LMO1 is a novel oncogene in colorectal cancer and its overexpression is a new predictive marker for anti-EGFR therapy.
Author:	Liu, Junguang\|Yan, Peiyun\|Jing, Niancai\|Yang, Jili
PMID:	24845030

1740.
Journal:	Curr Opin Oncol. 2014 Jul;26(4):454-61.
Title:	Ras in digestive oncology: from molecular biology to clinical implications.
Author:	Charette, Nicolas\|Vandeputte, Caroline\|Starkel, Peter
PMID:	24849046

1741.
Journal:	Rev Med Chil. 2014 Jan;142(1):55-60.
Title:	[BRAF gene mutation in wild-type KRAS patients with colorectal cancers].
Author:	Roa, Ivan\|Game, Anakaren\|Bizama, Carolina\|Schalper, Kurt
PMID:	24861115

1742.
Journal:	Clin Chim Acta. 2014 Sep 25;436:169-75.
Title:	Detection of KRAS codon 12 and 13 mutations by mutant-enriched PCR assay.
Author:	Chang, Ya-Sian\|Er, Tze-Kiong\|Lu, Hsiu-Chin\|Yeh, Kun-Tu\|Chang, Jan-Gowth
PMID:	24863805

1743.
Journal:	Arch Pharm (Weinheim). 2014 Sep;347(9):624-34.
Title:	Design and synthesis of quinazolinone tagged acridones as cytotoxic agents and their effects on EGFR tyrosine kinase.
Author:	Babu, Yarlagadda Rajesh\|Bhagavanraju, Mantripragada\|Reddy, Gade Deepak\|Peters, Godefridus J\|Prasad, Velivela V S Rajendra
PMID:	24866341

1744.
Journal:	PLoS One. 2014 May 29;9(5):e97719.
Title:	Combination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells.
Author:	Lou, Yun-feng\|Zou, Zheng-zhi\|Chen, Pin-jia\|Huang, Guo-bin\|Li, Bin\|Zheng, De-qing\|Yu, Xiu-rong\|Luo, Xiao-yong
PMID:	24874286

1745.
Journal:	World J Gastroenterol. 2014 May 28;20(20):6102-12.
Title:	Targeted therapy in advanced metastatic colorectal cancer: current concepts and perspectives.
Author:	Hohla, Florian\|Winder, Thomas\|Greil, Richard\|Rick, Ferenc G\|Block, Norman L\|Schally, Andrew V
PMID:	24876732

1746.
Journal:	Cancer Biomark. 2014;14(2-3):177-84.
Title:	The prognostic value of the Na(+)/ H(+) exchanger regulatory factor 1 (NHERF1) protein in cancer.
Author:	Saponaro, Concetta\|Malfettone, Andrea\|Dell'Endice, Teresa Stefania\|Brunetti, Anna Elisabetta\|Achimas-Cadariu, Patriciu\|Paradiso, Angelo\|Mangia, Anita
PMID:	24878819

1747.
Journal:	J Transl Med. 2014 May 26;12:147.
Title:	Detection of activated KRAS from cancer patient peripheral blood using a weighted enzymatic chip array.
Author:	Huang, Ming-Yii\|Liu, Hsueh-Chiao\|Yen, Li-Chen\|Chang, Jia-Yuan\|Huang, Jian-Jhang\|Wang, Jaw-Yuan\|Hsiao, Chao-Peng\|Lin, Shiu-Ru
PMID:	24884535

1748.
Journal:	Mol Cancer. 2014 May 31;13:135.
Title:	Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.
Author:	Imamura, Yu\|Lochhead, Paul\|Yamauchi, Mai\|Kuchiba, Aya\|Qian, Zhi Rong\|Liao, Xiaoyun\|Nishihara, Reiko\|Jung, Seungyoun\|Wu, Kana\|Nosho, Katsuhiko\|Wang, Yaoyu E\|Peng, Shouyong\|Bass, Adam J\|Haigis, Kevin M\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles S\|O
PMID:	24885062

1749.
Journal:	BMC Gastroenterol. 2014 May 21;14:96.
Title:	Up-regulation of CNDP2 facilitates the proliferation of colon cancer.
Author:	Xue, Conglong\|Zhang, Zhenwei\|Yu, Honglan\|Yu, Miao\|Yuan, Kaitao\|Yang, Ting\|Miao, Mingyong\|Shi, Hanping
PMID:	24885395

1750.
Journal:	Oncol Rep. 2014 Aug;32(2):821-8.
Title:	Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase.
Author:	Kundu, Juthika\|Choi, Bu Young\|Jeong, Chul-Ho\|Kundu, Joydeb Kumar\|Chun, Kyung-Soo
PMID:	24890449

1751.
Journal:	Cancer Med. 2014 Oct;3(5):1385-95.
Title:	Let-7 microRNA-binding-site polymorphism in the 3'UTR of KRAS and colorectal cancer outcome: a systematic review and meta-analysis.
Author:	Langevin, Scott M\|Christensen, Brock C
PMID:	24890702

1752.
Journal:	Clin Cancer Res. 2014 Aug 1;20(15):4115-28.
Title:	An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells.
Author:	Bae, Jeong A\|Yoon, Somy\|Park, So-Yeon\|Lee, Jae Hyuk\|Hwang, Jun-Eul\|Kim, Hangun\|Seo, Young-Woo\|Cha, Yoon Jin\|Hong, Sung Pil\|Kim, Hoguen\|Chung, Ik Joo\|Kim, Kyung Keun
PMID:	24893630

1753.
Journal:	Mol Cancer. 2014 Jun 4;13:141.
Title:	Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
Author:	Cho, Jeonghee\|Bass, Adam J\|Lawrence, Michael S\|Cibulskis, Kristian\|Cho, Ahye\|Lee, Shi-Nai\|Yamauchi, Mai\|Wagle, Nikhil\|Pochanard, Panisa\|Kim, Nayoung\|Park, Angela Kj\|Won, Jonghwa\|Hur, Hyung-Suk\|Greulich, Heidi\|Ogino, Shuji\|Sougnez, Carrie\|Voet, Douglas\|Tab
PMID:	24894453

1754.
Journal:	APMIS. 2014 Dec;122(12):1207-12.
Title:	Mutational and expressional analysis of ERBB3 gene in common solid cancers.
Author:	Choi, Mi Ryoung\|An, Chang Hyeok\|Chung, Yeun Jun\|Choi, Youn Jin\|Yoo, Nam Jin\|Lee, Sug Hyung
PMID:	24909266

1755.
Journal:	Mol Oncol. 2014 Sep 12;8(6):1084-94.
Title:	Acquired resistance to EGFR-targeted therapies in colorectal cancer.
Author:	Van Emburgh, Beth O\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Siena, Salvatore\|Bardelli, Alberto
PMID:	24913799

1756.
Journal:	Cancer Chemother Pharmacol. 2014 Jul;74(1):1-13.
Title:	Anti-EGFR MoAb treatment in colorectal cancer: limitations, controversies, and contradictories.
Author:	Cheng, Lei\|Ren, Wei\|Xie, Li\|Li, Ming\|Liu, Jiang\|Hu, Jing\|Liu, Bao-Rui\|Qian, Xiao-Ping
PMID:	24916545

1757.
Journal:	Clin Cancer Res. 2014 Dec 15;20(24):6429-38.
Title:	TGFalpha and amphiregulin paracrine network promotes resistance to EGFR blockade in colorectal cancer cells.
Author:	Hobor, Sebastijan\|Van Emburgh, Beth O\|Crowley, Emily\|Misale, Sandra\|Di Nicolantonio, Federica\|Bardelli, Alberto
PMID:	24916700

1758.
Journal:	Invest New Drugs. 2014 Dec;32(6):1197-203.
Title:	A multicenter phase 1 study of PX-866 and cetuximab in patients with metastatic colorectal carcinoma or recurrent/metastatic squamous cell carcinoma of the head and neck.
Author:	Bowles, Daniel W\|Senzer, Neil\|Hausman, Diana\|Peterson, Scott\|Vo, Alex\|Walker, Luke\|Cohen, Roger B\|Jimeno, Antonio
PMID:	24916771

1759.
Journal:	Klin Onkol. 2014;27(3):166-72.
Title:	[The combination of neoadjuvant chemoradiotherapy and epidermal growth factor receptor inhibitors in the treatment of rectal adenocarcinoma].
Author:	Richter, I\|Dvorak, J\|Bartos, J
PMID:	24918274

1760.
Journal:	Anticancer Res. 2014 Jun;34(6):3083-92.
Title:	Detection of circulating tumor cells in colorectal and gastric cancer using a multiplex PCR assay.
Author:	Vaiopoulos, Aristeidis G\|Kostakis, Ioannis D\|Gkioka, Eliona\|Athanasoula, Kalliopi Ch\|Pikoulis, Emmanouil\|Papalambros, Alexandros\|Christopoulos, Panagiotis\|Gogas, Helen\|Kouraklis, Gregory\|Koutsilieris, Michael
PMID:	24922677

1761.
Journal:	Pharmacol Res. 2014 Sep;87:42-59.
Title:	ErbB/HER protein-tyrosine kinases: Structures and small molecule inhibitors.
Author:	Roskoski, Robert Jr
PMID:	24928736

1762.
Journal:	PLoS One. 2014 Jun 18;9(6):e99590.
Title:	Heterogeneous EGFR gene copy number increase is common in colorectal cancer and defines response to anti-EGFR therapy.
Author:	Algars, Annika\|Avoranta, Tuulia\|Osterlund, Pia\|Lintunen, Minnamaija\|Sundstrom, Jari\|Jokilehto, Terhi\|Ristimaki, Ari\|Ristamaki, Raija\|Carpen, Olli
PMID:	24940619

1763.
Journal:	Ann Oncol. 2014 Sep;25(9):1756-61.
Title:	Clinical activity of FOLFIRI plus cetuximab according to extended gene mutation status by next-generation sequencing: findings from the CAPRI-GOIM trial.
Author:	Ciardiello, F\|Normanno, N\|Maiello, E\|Martinelli, E\|Troiani, T\|Pisconti, S\|Giuliani, F\|Barone, C\|Carteni, G\|Rachiglio, A M\|Montesarchio, V\|Tonini, G\|Rizzi, D\|Cinieri, S\|Bordonaro, R\|Febbraro, A\|De Vita, F\|Orditura, M\|Fenizia, F\|Lambiase, M\|Rinaldi, A\|Tatan
PMID:	24942275

1764.
Journal:	Oncotarget. 2014 Jul 15;5(13):4868-80.
Title:	Afatinib and its encapsulated polymeric micelles inhibits HER2-overexpressed colorectal tumor cell growth in vitro and in vivo.
Author:	Guan, Siao-Syun\|Chang, Jungshan\|Cheng, Chun-Chia\|Luo, Tsai-Yueh\|Ho, Ai-Sheng\|Wang, Chia-Chi\|Wu, Cheng-Tien\|Liu, Shing-Hwa
PMID:	24947902

1765.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Jun;17(6):565-9.
Title:	[Sensitivity study on preoperative individual concomitant radiochemotherapy for rectal cancer].
Author:	Pei, Haiping\|Pei, Qian\|Wu, Shaobin\|Zhu, Hong
PMID:	24953363

1766.
Journal:	Chirurgia (Bucur). 2014 May-Jun;109(3):383-9.
Title:	Efficacy of cetuximab in metastatic colon cancer - case report.
Author:	Grigorean, V T\|Ciuhu, A N\|Rahnea Nita, G\|Strambu, V\|Straja, D N\|Popescu, M\|Sandu, A M\|Rahnea Nita, R A
PMID:	24956345

1767.
Journal:	Br J Cancer. 2014 Jul 29;111(3):430-6.
Title:	Phase II study of gemcitabine, oxaliplatin in combination with panitumumab in KRAS wild-type unresectable or metastatic biliary tract and gallbladder cancer.
Author:	Hezel, A F\|Noel, M S\|Allen, J N\|Abrams, T A\|Yurgelun, M\|Faris, J E\|Goyal, L\|Clark, J W\|Blaszkowsky, L S\|Murphy, J E\|Zheng, H\|Khorana, A A\|Connolly, G C\|Hyrien, O\|Baran, A\|Herr, M\|Ng, K\|Sheehan, S\|Harris, D J\|Regan, E\|Borger, D R\|Iafrate, A J\|Fuchs, C\|Ryan
PMID:	24960403

1768.
Journal:	Oncotarget. 2014 Jul 15;5(13):5138-52.
Title:	ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.
Author:	Lee, Hyunji\|Lee, Hyunjung\|Chin, Hyunjung\|Kim, Kyoungmi\|Lee, Daekee
PMID:	24970817

1769.
Journal:	Br J Cancer. 2014 Aug 12;111(4):749-55.
Title:	Epidermal growth factor receptor (EGFR) and prostaglandin-endoperoxide synthase 2 (PTGS2) are prognostic biomarkers for patients with resected colorectal cancer liver metastases.
Author:	Goos, J A C M\|Hiemstra, A C\|Coupe, V M H\|Diosdado, B\|Kooijman, W\|Delis-Van Diemen, P M\|Karga, C\|Belien, J A M\|Menke-van der Houven van Oordt, C W\|Geldof, A A\|Meijer, G A\|Hoekstra, O S\|Fijneman, R J A
PMID:	24983372

1770.
Journal:	Crit Rev Oncol Hematol. 2014 Dec;92(3):218-26.
Title:	Potentially resectable metastatic colorectal cancer: an individualized approach to conversion therapy.
Author:	Marino, Donatella\|Leone, Francesco\|D'Avanzo, Francesca\|Ribero, Dario\|Capussotti, Lorenzo\|Aglietta, Massimo
PMID:	24985058

1771.
Journal:	Cancer Res. 2014 Jul 15;74(14):3647-51.
Title:	MET-mediated resistance to EGFR inhibitors: an old liaison rooted in colorectal cancer stem cells.
Author:	Boccaccio, Carla\|Luraghi, Paolo\|Comoglio, Paolo M
PMID:	24986519

1772.
Journal:	Int J Oncol. 2014 Sep;45(3):1167-74.
Title:	Next-generation sequencing analysis of lung and colon carcinomas reveals a variety of genetic alterations.
Author:	Chevrier, Sandy\|Arnould, Laurent\|Ghiringhelli, Francois\|Coudert, Bruno\|Fumoleau, Pierre\|Boidot, Romain
PMID:	24990411

1773.
Journal:	J Clin Pathol. 2014 Sep;67(9):751-7.
Title:	RAS testing of colorectal carcinoma-a guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Group.
Author:	Wong, Newton A C S\|Gonzalez, David\|Salto-Tellez, Manuel\|Butler, Rachel\|Diaz-Cano, Salvador J\|Ilyas, Mohammad\|Newman, William\|Shaw, Emily\|Taniere, Philippe\|Walsh, Shaun V
PMID:	24996433

1774.
Journal:	Hum Pathol. 2014 Sep;45(9):1866-71.
Title:	Adenoma and carcinoma components in colonic tumors show discordance for KRAS mutation.
Author:	Hershkovitz, Dov\|Simon, Einav\|Bick, Tova\|Prinz, Elad\|Noy, Shawna\|Sabo, Edmond\|Ben-Izhak, Ofer\|Vieth, Michael
PMID:	24998492

1775.
Journal:	Oncotarget. 2014 Jun 15;5(11):3673-84.
Title:	beta1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells.
Author:	Che, Mei-Ieng\|Huang, John\|Hung, Ji-Shiang\|Lin, Yo-Chuen\|Huang, Miao-Juei\|Lai, Hong-Shiee\|Hsu, Wen-Ming\|Liang, Jin-Tung\|Huang, Min-Chuan
PMID:	25003232

1776.
Journal:	J Clin Pathol. 2014 Sep;67(9):764-7.
Title:	Comparison of KRAS mutation analysis of colorectal cancer samples by standard testing and next-generation sequencing.
Author:	Kothari, Nishi\|Schell, Michael J\|Teer, Jamie K\|Yeatman, Timothy\|Shibata, David\|Kim, Richard
PMID:	25004944

1777.
Journal:	Oncol Lett. 2014 Aug;8(2):561-565.
Title:	Comparison of K-ras mutations in lung, colorectal and gastric cancer.
Author:	Peng, Nanqiu\|Zhao, Xintai
PMID:	25013470

1778.
Journal:	J Biomed Nanotechnol. 2014 Aug;10(8):1416-28.
Title:	Actively targeted cetuximab conjugated gamma-poly(glutamic acid)-docetaxel nanomedicines for epidermal growth factor receptor over expressing colon cancer cells.
Author:	Maya, S\|Sarmento, Bruno\|Lakshmanan, Vinoth-Kumar\|Menon, Deepthy\|Jayakumar, R
PMID:	25016642

1779.
Journal:	Int J Oncol. 2014 Oct;45(4):1583-93.
Title:	Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity.
Author:	Nakata, Susumu\|Tanaka, Harunari\|Ito, Yuichi\|Hara, Masayasu\|Fujita, Mitsugu\|Kondo, Eisaku\|Kanemitsu, Yukihide\|Yatabe, Yasushi\|Nakanishi, Hayao
PMID:	25017791

1780.
Journal:	Dig Dis Sci. 2014 Oct;59(10):2367-80.
Title:	Differential regulation of EGFR-MAPK signaling by deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA) in colon cancer.
Author:	Centuori, Sara M\|Martinez, Jesse D
PMID:	25027205

1781.
Journal:	Ann Surg Oncol. 2014 Dec;21 Suppl 4:S743-9.
Title:	Clinical significance of GAB2, a scaffolding/docking protein acting downstream of EGFR in human colorectal cancer.
Author:	Matsumura, Tae\|Sugimachi, Keishi\|Takahashi, Yusuke\|Uchi, Ryutaro\|Sawada, Genta\|Ueda, Masami\|Hirata, Hidenari\|Sakimura, Shotaro\|Ueo, Hiroki\|Takano, Yuki\|Kurashige, Junji\|Shinden, Yoshiaki\|Eguchi, Hidetoshi\|Sudo, Tomoya\|Yamamoto, Hirofumi\|Doki, Yuichiro\|Mor
PMID:	25029990

1782.
Journal:	Neoplasma. 2014;61(5):514-22.
Title:	SKLB-287, anovel oral multikinase inhibitor of EGFR and VEGFR2, exhibits potent antitumor activity in LoVo colorectal tumor model.
Author:	Chen, X\|Liu, Y\|Yang, H-W\|Zhou, S\|Cheng, C\|Zheng, M-W\|Zhong, L\|Fu, X-Y\|Pan, Y-L\|Ma, S\|Tang, Y\|Chen, Y-Z\|Li, L-L\|Yang, S-Y
PMID:	25030434

1783.
Journal:	Biomed Res Int. 2014;2014:591867.
Title:	Current approaches for predicting a lack of response to anti-EGFR therapy in KRAS wild-type patients.
Author:	Er, Tze-Kiong\|Chen, Chih-Chieh\|Bujanda, Luis\|Herreros-Villanueva, Marta
PMID:	25032217

1784.
Journal:	J Oncol Pract. 2014 Sep;10(5):308-14.
Title:	Oncologists' response to new data regarding the use of epidermal growth factor receptor inhibitors in colorectal cancer.
Author:	Dotan, Efrat\|Li, Tianyu\|Hall, Michael J\|Meropol, Neal J\|Beck, J Robert\|Wong, Yu-Ning
PMID:	25052499

1785.
Journal:	Genes Cancer. 2014 Mar;5(3-4):113-26.
Title:	Amphiregulin and PTEN evoke a multimodal mechanism of acquired resistance to PI3K inhibition.
Author:	Edgar, Kyle A\|Crocker, Lisa\|Cheng, Eric\|Wagle, Marie-Claire\|Wongchenko, Matthew\|Yan, Yibing\|Wilson, Timothy R\|Dompe, Nicholas\|Neve, Richard M\|Belvin, Marcia\|Sampath, Deepak\|Friedman, Lori S\|Wallin, Jeffrey J
PMID:	25053989

1786.
Journal:	Ann Oncol. 2014 Oct;25(10):1995-2001.
Title:	Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features.
Author:	Missiaglia, E\|Jacobs, B\|D'Ario, G\|Di Narzo, A F\|Soneson, C\|Budinska, E\|Popovici, V\|Vecchione, L\|Gerster, S\|Yan, P\|Roth, A D\|Klingbiel, D\|Bosman, F T\|Delorenzi, M\|Tejpar, S
PMID:	25057166

1787.
Journal:	Theranostics. 2014 Jul 1;4(9):893-903.
Title:	An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis.
Author:	Turker, N Selcan\|Heidari, Pedram\|Kucherlapati, Raju\|Kucherlapati, Melanie\|Mahmood, Umar
PMID:	25057314

1788.
Journal:	Med Oncol. 2014 Sep;31(9):124.
Title:	Molecular spectrum of KRAS, BRAF, and PIK3CA gene mutation: determination of frequency, distribution pattern in Indian colorectal carcinoma.
Author:	Bisht, Swati\|Ahmad, Firoz\|Sawaimoon, Satyakam\|Bhatia, Simi\|Das, Bibhu Ranjan
PMID:	25073438

1789.
Journal:	Clin Colorectal Cancer. 2014 Sep;13(3):192-8.
Title:	Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies in older adults with metastatic colorectal cancer.
Author:	Dotan, Efrat\|Devarajan, Karthik\|D'Silva, A James\|Beck, Andrew\|Kloth, Dwight D\|Cohen, Steven J\|Denlinger, Crystal
PMID:	25074246

1790.
Journal:	PLoS One. 2014 Aug 1;9(8):e103159.
Title:	Sporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study.
Author:	Kirzin, Sylvain\|Marisa, Laetitia\|Guimbaud, Rosine\|De Reynies, Aurelien\|Legrain, Michele\|Laurent-Puig, Pierre\|Cordelier, Pierre\|Pradere, Bernard\|Bonnet, Delphine\|Meggetto, Fabienne\|Portier, Guillaume\|Brousset, Pierre\|Selves, Janick
PMID:	25083765

1791.
Journal:	PLoS One. 2014 Aug 4;9(8):e103551.
Title:	Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independent of KRAS mutational status.
Author:	Lee, Jeeyun\|Jain, Anjali\|Kim, Phillip\|Lee, Tani\|Kuller, Anne\|Princen, Fred\|In-GuDo\|Kim, Suk Hyeong\|Park, Joon Oh\|Park, Young Suk\|Singh, Sharat\|Kim, Hee Cheol
PMID:	25090459

1792.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):9732-43.
Title:	Beyond KRAS: Predictive factors of the efficacy of anti-EGFR monoclonal antibodies in the treatment of metastatic colorectal cancer.
Author:	De Stefano, Alfonso\|Carlomagno, Chiara
PMID:	25110411

1793.
Journal:	PLoS One. 2014 Aug 14;9(8):e104891.
Title:	Epidermal growth factor stimulates nuclear factor-kappaB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
Author:	Lien, Gi-Shih\|Wu, Ming-Shun\|Bien, Mauo-Ying\|Chen, Chien-Hsin\|Lin, Chien-Huang\|Chen, Bing-Chang
PMID:	25122478

1794.
Journal:	Cell Prolif. 2014 Oct;47(5):435-47.
Title:	In vitro combined treatment with cetuximab and trastuzumab inhibits growth of colon cancer cells.
Author:	Luca, T\|Barresi, V\|Privitera, G\|Musso, N\|Caruso, M\|Condorelli, D F\|Castorina, S
PMID:	25131935

1795.
Journal:	BMC Cancer. 2014 Aug 18;14:599.
Title:	Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs.
Author:	Samuel, Temesgen\|Fadlalla, Khalda\|Gales, Dominique N\|Putcha, Balananda D K\|Manne, Upender
PMID:	25134433

1796.
Journal:	Clin Cancer Res. 2014 Dec 15;20(24):6227-9.
Title:	Paracrine network: another step in the complexity of resistance to EGFR blockade?
Author:	Salazar, Ramon\|Capella, Gabriel\|Tabernero, Josep
PMID:	25139340

1797.
Journal:	Int J Environ Res Public Health. 2014 Aug 25;11(9):8645-60.
Title:	Clinical and metabolic parameters in non-small cell lung carcinoma and colorectal cancer patients with and without KRAS mutations.
Author:	Yilmaz, Ahmet\|Mohamed, Nehad\|Patterson, Kara A\|Tang, Yan\|Shilo, Konstantin\|Villalona-Calero, Miguel A\|Davis, Michael E\|Zhou, Xiao-Ping\|Frankel, Wendy\|Otterson, Gregory A\|Zhao, Weiqiang
PMID:	25158139

1798.
Journal:	Genome Biol. 2014 Aug 28;15(8):454.
Title:	Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.
Author:	Brannon, A Rose\|Vakiani, Efsevia\|Sylvester, Brooke E\|Scott, Sasinya N\|McDermott, Gregory\|Shah, Ronak H\|Kania, Krishan\|Viale, Agnes\|Oschwald, Dayna M\|Vacic, Vladimir\|Emde, Anne-Katrin\|Cercek, Andrea\|Yaeger, Rona\|Kemeny, Nancy E\|Saltz, Leonard B\|Shia, Jinru
PMID:	25164765

1799.
Journal:	Nutr Cancer. 2014;66(6):999-1008.
Title:	The ethanolic extract of bark from Salix aegyptiaca L. inhibits the metastatic potential and epithelial to mesenchymal transition of colon cancer cell lines.
Author:	Enayat, Shabnam\|Banerjee, Sreeparna
PMID:	25175673

1800.
Journal:	Clin Cancer Res. 2014 Sep 1;20(17):4499-4510.
Title:	A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy.
Author:	Saridaki, Zenia\|Weidhaas, Joanne B\|Lenz, Heinz-Josef\|Laurent-Puig, Pierre\|Jacobs, Bart\|De Schutter, Jef\|De Roock, Wendy\|Salzman, David W\|Zhang, Wu\|Yang, Dongyun\|Pilati, Camilla\|Bouche, Olivier\|Piessevaux, Hubert\|Tejpar, Sabine
PMID:	25183481

1801.
Journal:	PLoS One. 2014 Sep 8;9(9):e107165.
Title:	EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.
Author:	Moller, Yvonne\|Siegemund, Martin\|Beyes, Sven\|Herr, Ricarda\|Lecis, Daniele\|Delia, Domenico\|Kontermann, Roland\|Brummer, Tilman\|Pfizenmaier, Klaus\|Olayioye, Monilola A
PMID:	25198428

1802.
Journal:	Cancer Prev Res (Phila). 2014 Nov;7(11):1160-9.
Title:	The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats.
Author:	Ivancic, Melanie M\|Irving, Amy A\|Jonakin, Kelli G\|Dove, William F\|Sussman, Michael R
PMID:	25200834

1803.
Journal:	Onco Targets Ther. 2014 Aug 25;7:1487-96.
Title:	The involvement of Kras gene 3'-UTR polymorphisms in risk of cancer and influence on patient response to anti-EGFR therapy in metastatic colorectal cancer: a meta-analysis.
Author:	Ying, Hou-Qun\|Wang, Feng\|He, Bang-Shun\|Pan, Yu-Qin\|Gao, Tian-Yi\|Xu, Ye-Qiong\|Li, Rui\|Deng, Qi-Wen\|Sun, Hui-Lin\|Wang, Shu-Kui
PMID:	25210463

1804.
Journal:	Clin Cancer Res. 2014 Nov 15;20(22):5848-5859.
Title:	The renin-angiotensin system mediates EGF receptor-vitamin d receptor cross-talk in colitis-associated colon cancer.
Author:	Dougherty, Urszula\|Mustafi, Reba\|Sadiq, Farhana\|Almoghrabi, Anas\|Mustafi, Devkumar\|Kreisheh, Maggi\|Sundaramurthy, Sumana\|Liu, Weicheng\|Konda, Vani J\|Pekow, Joel\|Khare, Sharad\|Hart, John\|Joseph, Loren\|Wyrwicz, Alice\|Karczmar, Gregory S\|Li, Yan Chun\|Bissonn
PMID:	25212605

1805.
Journal:	PLoS One. 2014 Sep 26;9(9):e107926.
Title:	PCR-based assays versus direct sequencing for evaluating the effect of KRAS status on anti-EGFR treatment response in colorectal cancer patients: a systematic review and meta-analysis.
Author:	Shan, Lianfeng\|Li, Ming\|Ma, Jianzhong\|Zhang, Huidan
PMID:	25260023

1806.
Journal:	Oncotarget. 2014 Sep 30;5(18):8602-13.
Title:	Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma.
Author:	Goldshmit, Yona\|Trangle, Sari Schokoroy\|Kloog, Yoel\|Pinkas-Kramarski, Ronit
PMID:	25261371

1807.
Journal:	Clin Biochem. 2014 Dec;47(18):340-3.
Title:	High-throughput screening of extended RAS mutations based on high-resolution melting analysis for prediction of anti-EGFR treatment efficacy in colorectal carcinoma.
Author:	Ishige, Takayuki\|Itoga, Sakae\|Sato, Kenichi\|Kitamura, Kouichi\|Nishimura, Motoi\|Sawai, Setsu\|Matsushita, Kazuyuki\|Suzuki, Kazufumi\|Ota, Satoshi\|Miyauchi, Hideaki\|Matsubara, Hisahiro\|Nakatani, Yukio\|Nomura, Fumio
PMID:	25262986

1808.
Journal:	Diagn Pathol. 2014 Sep 30;9:187.
Title:	KRAS and BRAF mutational status in colon cancer from Albanian patients.
Author:	Martinetti, Daniela\|Costanzo, Rosario\|Kadare, Shahin\|Alimehmeti, Mehdiu\|Colarossi, Cristina\|Canzonieri, Vincenzo\|Berretta, Massimiliano\|Memeo, Lorenzo
PMID:	25267307

1809.
Journal:	Anticancer Res. 2014 Oct;34(10):5599-607.
Title:	Overexpression of the ITGAV gene is associated with progression and spread of colorectal cancer.
Author:	Waisberg, Jaques\|De Souza Viana, Luciano\|Affonso Junior, Renato Jose\|Silva, Sandra Regina Morini\|Denadai, Marcos Vinicius Araujo\|Margeotto, Fernando Beani\|De Souza, Carolina Salinas\|Matos, Delcio
PMID:	25275062

1810.
Journal:	Acta Neuropathol. 2014 Dec;128(6):879-91.
Title:	Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues.
Author:	Berghoff, Anna Sophie\|Bartsch, Rupert\|Wohrer, Adelheid\|Streubel, Berthold\|Birner, Peter\|Kros, Johan M\|Brastianos, Priscilla K\|von Deimling, Andreas\|Preusser, Matthias
PMID:	25287912

1811.
Journal:	Cancer Treat Rev. 2014 Dec;40(10):1221-9.
Title:	Infectious complications in cancer patients treated with anti-EGFR monoclonal antibodies cetuximab and panitumumab: a systematic review and meta-analysis.
Author:	Funakoshi, Tomohiro\|Suzuki, Maya\|Tamura, Kazuo
PMID:	25288497

1812.
Journal:	Cancer Discov. 2014 Nov;4(11):1269-80.
Title:	Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution.
Author:	Misale, Sandra\|Di Nicolantonio, Federica\|Sartore-Bianchi, Andrea\|Siena, Salvatore\|Bardelli, Alberto
PMID:	25293556

1813.
Journal:	EMBO Rep. 2014 Nov;15(11):1210-8.
Title:	Iro/IRX transcription factors negatively regulate Dpp/TGF-beta pathway activity during intestinal tumorigenesis.
Author:	Martorell, Oscar\|Barriga, Francisco M\|Merlos-Suarez, Anna\|Stephan-Otto Attolini, Camille\|Casanova, Jordi\|Batlle, Eduard\|Sancho, Elena\|Casali, Andreu
PMID:	25296644

1814.
Journal:	Oncotarget. 2014 Oct 30;5(20):10070-83.
Title:	The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling.
Author:	Asbagh, Layka Abbasi\|Vazquez, Iria\|Vecchione, Loredana\|Budinska, Eva\|De Vriendt, Veerle\|Baietti, Maria Francesca\|Steklov, Mikhail\|Jacobs, Bart\|Hoe, Nicholas\|Singh, Sharat\|Imjeti, Naga-Sailaja\|Zimmermann, Pascale\|Sablina, Anna\|Tejpar, Sabine
PMID:	25301722

1815.
Journal:	J Natl Compr Canc Netw. 2014 Oct;12(10):1433-42.
Title:	Predictive biomarkers for anti-epidermal growth factor receptor therapy: beyond KRAS testing.
Author:	Ashraf, Noman\|Kothari, Nishi\|Kim, Richard
PMID:	25313182

1816.
Journal:	Br J Cancer. 2014 Nov 11;111(10):1965-76.
Title:	Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer.
Author:	Wang, X\|Zuo, D\|Chen, Y\|Li, W\|Liu, R\|He, Y\|Ren, L\|Zhou, L\|Deng, T\|Wang, X\|Ying, G\|Ba, Y
PMID:	25321193

1817.
Journal:	Clin Cancer Res. 2014 Dec 15;20(24):6346-56.
Title:	Circulating pEGFR is a candidate response biomarker of cetuximab therapy in colorectal cancer.
Author:	Katsila, Theodora\|Juliachs, Merce\|Gregori, Josep\|Macarulla, Teresa\|Villarreal, Laura\|Bardelli, Alberto\|Torrance, Chris\|Elez, Elena\|Tabernero, Josep\|Villanueva, Josep
PMID:	25324142

1818.
Journal:	Tumour Biol. 2014 Dec;35(12):11851-4.
Title:	Somatic mutations of the HER2 in metastatic breast cancer.
Author:	Fang, Yi\|Jiang, Yanxia\|Wang, Xin\|Yang, Xue\|Gao, Yinqi\|Wang, Jing
PMID:	25326805

1819.
Journal:	Mol Cancer Ther. 2014 Dec;13(12):3230-40.
Title:	Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypes.
Author:	San Lucas, F Anthony\|Fowler, Jerry\|Chang, Kyle\|Kopetz, Scott\|Vilar, Eduardo\|Scheet, Paul
PMID:	25349306

1820.
Journal:	Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15964-8.
Title:	Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers.
Author:	Bozic, Ivana\|Nowak, Martin A
PMID:	25349424

1821.
Journal:	Oncotarget. 2014 Dec 15;5(23):12304-16.
Title:	Targeting cytosolic phospholipase A2 alpha in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation.
Author:	Zheng, Zhong\|He, Xiangyi\|Xie, Chanlu\|Hua, Sheng\|Li, Jianfang\|Wang, Tingfeng\|Yao, Mu\|Vignarajan, Soma\|Teng, Ying\|Hejazi, Leila\|Liu, Bingya\|Dong, Qihan
PMID:	25365190

1822.
Journal:	Curr Drug Targets. 2014;15(13):1225-30.
Title:	Beyond RAS: the role of epidermal growth factor receptor (EGFR) and its network in the prediction of clinical outcome during anti-EGFR treatment in colorectal cancer patients.
Author:	Giampieri, Riccardo\|Aprile, Giuseppe\|Del Prete, Michela\|Faloppi, Luca\|Bianconi, Maristella\|Bonotto, Marta\|Fasola, Giampiero\|Cascinu, Stefano\|Scartozzi, Mario
PMID:	25382208

1823.
Journal:	Sci Signal. 2014 Nov 11;7(351):ra107.
Title:	Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Author:	Belmont, Peter J\|Jiang, Ping\|McKee, Trevor D\|Xie, Tao\|Isaacson, Jason\|Baryla, Nicole E\|Roper, Jatin\|Sinnamon, Mark J\|Lee, Nathan V\|Kan, Julie L C\|Guicherit, Oivin\|Wouters, Bradly G\|O'Brien, Catherine A\|Shields, David\|Olson, Peter\|VanArsdale, Todd\|Weinrich
PMID:	25389372

1824.
Journal:	Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2965-70.
Title:	Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type.
Author:	Gatalica, Zoran\|Snyder, Carrie\|Maney, Todd\|Ghazalpour, Anatole\|Holterman, Daniel A\|Xiao, Nianqing\|Overberg, Peggy\|Rose, Inga\|Basu, Gargi D\|Vranic, Semir\|Lynch, Henry T\|Von Hoff, Daniel D\|Hamid, Omid
PMID:	25392179

1825.
Journal:	Molecules. 2014 Nov 13;19(11):18558-73.
Title:	Synthetic genistein glycosides inhibiting EGFR phosphorylation enhance the effect of radiation in HCT 116 colon cancer cells.
Author:	Gruca, Aleksandra\|Krawczyk, Zdzislaw\|Szeja, Wieslaw\|Grynkiewicz, Grzegorz\|Rusin, Aleksandra
PMID:	25401399

1826.
Journal:	BMC Cancer. 2014 Nov 22;14:863.
Title:	Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer.
Author:	Mitsui, Keigo\|Yonezawa, Masaoki\|Tatsuguchi, Atsushi\|Shinji, Seiichi\|Gudis, Katya\|Tanaka, Shu\|Fujimori, Shunji\|Sakamoto, Choitsu
PMID:	25416285

1827.
Journal:	PLoS One. 2014 Nov 26;9(11):e113186.
Title:	c-Met targeting enhances the effect of irradiation and chemical agents against malignant colon cells harboring a KRAS mutation.
Author:	Li, Yingbo\|Wang, Jinxi\|Gao, Xing\|Han, Weihua\|Zheng, Yongxiang\|Xu, Huan\|Zhang, Chuanling\|He, Qiuchen\|Zhang, Lihe\|Li, Zhongxin\|Zhou, Demin
PMID:	25427200

1828.
Journal:	Cytometry B Clin Cytom. 2014 Nov 28.
Title:	Isolating EGFR Overexpressing Carcinoma Cells from Human Whole Blood by Bio-Ferrography.
Author:	Levi, Ofer\|Shapira, Assaf\|Tal, Baruch\|Benhar, Itai\|Eliaz, Noam
PMID:	25447785

1829.
Journal:	Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17995-8000.
Title:	Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer.
Author:	Stachnik, Agnes\|Yuen, Tony\|Iqbal, Jameel\|Sgobba, Miriam\|Gupta, Yogesh\|Lu, Ping\|Colaianni, Graziana\|Ji, Yaoting\|Zhu, Ling-Ling\|Kim, Se-Min\|Li, Jianhua\|Liu, Peng\|Izadmehr, Sudeh\|Sangodkar, Jaya\|Scherer, Thomas\|Mujtaba, Shiraz\|Galsky, Matthew\|Gomez, Jorge\|Ep
PMID:	25453078

1830.
Journal:	Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17989-94.
Title:	Bisphosphonates inactivate human EGFRs to exert antitumor actions.
Author:	Yuen, Tony\|Stachnik, Agnes\|Iqbal, Jameel\|Sgobba, Miriam\|Gupta, Yogesh\|Lu, Ping\|Colaianni, Graziana\|Ji, Yaoting\|Zhu, Ling-Ling\|Kim, Se-Min\|Li, Jianhua\|Liu, Peng\|Izadmehr, Sudeh\|Sangodkar, Jaya\|Bailey, Jack\|Latif, Yathin\|Mujtaba, Shiraz\|Epstein, Solomon\|Dav
PMID:	25453081

1831.
Journal:	Biomed Pharmacother. 2014 Oct;68(8):1089-97.
Title:	Down-regulation of sphingosine kinase 2 (SphK2) increases the effects of all-trans-retinoic acid (ATRA) on colon cancer cells.
Author:	Chu, Jia-Hui\|Gao, Zu-Hua\|Qu, Xian-Jun
PMID:	25455157

1832.
Journal:	Cancer Treat Rev. 2014 Dec;40(10):1171-81.
Title:	Navigating later lines of treatment for advanced colorectal cancer - optimizing targeted biological therapies to improve outcomes.
Author:	Gill, Sharlene\|Dowden, Scot\|Colwell, Bruce\|Collins, Loretta L\|Berry, Scott
PMID:	25458604

1833.
Journal:	Oncotarget. 2014 Dec 15;5(23):11847-56.
Title:	The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells.
Author:	Kawakami, Hisato\|Okamoto, Isamu\|Yonesaka, Kimio\|Okamoto, Kunio\|Shibata, Kiyoko\|Shinkai, Yume\|Sakamoto, Haruka\|Kitano, Michiko\|Tamura, Takao\|Nishio, Kazuto\|Nakagawa, Kazuhiko
PMID:	25474137

1834.
Journal:	Indian J Cancer. 2014 July-September;51(3):358-362.
Title:	Epidermal growth factor receptor gene expression evaluation in colorectal cancer patients.
Author:	Motalleb, G\|Pourrahmat, E\|Najafi, S\|Rashki, A\|Moghadam, A Yegane\|Mazaheri, M\|Jahantigh, M\|Sabagh, K\|Sanadgol, N\|Najafi, S\|Talaee, R
PMID:	25494138

1835.
Journal:	J Carcinog. 2014 Nov 27;13:13.
Title:	The advent of precision therapy in gastrointestinal malignancies: Targeting the human epidermal growth factor receptor family in colorectal and esophagogastric cancer.
Author:	Desautels, Danielle\|Harlos, Craig\|Czaykowski, Piotr
PMID:	25525412

1836.
Journal:	Oncotarget. 2014 Nov 30;5(22):11017-28.
Title:	Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue.
Author:	David, Kerstin A\|Unger, Florian T\|Uhlig, Philipp\|Juhl, Hartmut\|Moore, Helen M\|Compton, Carolyn\|Nashan, Bjorn\|Dorner, Arnulf\|de Weerth, Andreas\|Zornig, Carsten
PMID:	25526028

1837.
Journal:	Cancer Biol Ther. 2014;15(12):1677-87.
Title:	EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells.
Author:	Katona, Bryson W\|Liu, Yuanyuan\|Ma, Anqi\|Jin, Jian\|Hua, Xianxin
PMID:	25535899

1838.
Journal:	F1000Prime Rep. 2014 Nov 4;6:108.
Title:	Management of colorectal cancer.
Author:	Stintzing, Sebastian
PMID:	25580262

1839.
Journal:	Oncoscience. 2014 Aug 7;1(8):540-9.
Title:	Dual EGFR inhibition in combination with anti-VEGF treatment in colorectal cancer.
Author:	Falchook, Gerald S\|Naing, Aung\|Wheler, Jennifer J\|Tsimberidou, Apostolia M\|Zinner, Ralph\|Hong, David S\|Fu, Siqing\|Piha-Paul, Sarina A\|Janku, Filip\|Hess, Kenneth R\|Bastida, Christel\|Kurzrock, Razelle
PMID:	25594061

1840.
Journal:	Pol J Pathol. 2014 Dec;65(4):257-66.
Title:	Molecular pathology of colorectal cancer.
Author:	Bosman, Ft\|Yan, P
PMID:	25693079

1841.
Journal:	Hepatogastroenterology. 2014 Nov-Dec;61(136):2215-8.
Title:	Comparison analysis in synchronous and metachronous metastatic colorectal cancer based on microarray expression profile.
Author:	Wang, Da-dong\|Xu, Yong\|Tu, Yu-liang\|Tan, Xiang-long\|Zhu, Zi-man\|Han, Ming-ming\|Dou, Chun-qing\|Zeng, Jian-ping\|Tan, Jing-wang\|Du, Jun-dong\|Jiao, Hua-bou\|Cai, Shou-wang
PMID:	25699354

1842.
Journal:	Gan To Kagaku Ryoho. 2014 Nov;41(12):1701-3.
Title:	[A case of postoperative colon cancer with peritoneal dissemination in which a long-term response was achieved using panitumumab maintenance therapy].
Author:	Takahashi, Hidenori\|Ishikawa, Toshiaki\|Iwata, Noriko\|Baba, Hironobu\|Someno, Yasunori\|Okazaki, Satoshi\|Matsuyama, Takatoshi\|Ishiguro, Megumi\|Kobayashi, Hirotoshi\|Iida, Satoru\|Uetake, Hiroyuki\|Sugihara, Kenichi
PMID:	25731301

1843.
Journal:	Gan To Kagaku Ryoho. 2014 Nov;41(12):2145-7.
Title:	[Mixed adenoneuroendocrine carcinoma with multiple liver metastases successfully treated by cetuximab/CPT-11 chemotherapy followed by curative resection - a case report].
Author:	Tani, Keigo\|Seyama, Yasuji\|Inada, Kentaro\|Matsuoka, Yujiro\|Takahashi, Masamichi\|Tanizawa, Tohru\|Warabi, Masahiro\|Nasu, Keiichi\|Wada, Ikuo\|Maeshiro, Tsuyoshi\|Miyamoto, Sachio\|Umekita, Nobutaka
PMID:	25731451

1844.
Journal:
Title:
Author:	Meleth, Sreelatha\|Reeder-Hayes, Katherine\|Ashok, Mahima\|Clark, Robert\|Funkhouser, William\|Wines, Roberta\|Hill, Christine\|Shanahan, Ellen\|McClure, Emily\|Burson, Katrina\|Coker-Schwimmer, Manny\|Garge, Nikhil\|Jonas, Daniel E
PMID:	25905152

1845.
Journal:	EXCLI J. 2014 May 26;13:573-85. eCollection 2014.
Title:	EGFR tyrosine kinase targeted compounds: in vitro antitumor activity and molecular modeling studies of new benzothiazole and pyrimido[2,1-b]benzothiazole derivatives.
Author:	Gabr, Moustafa T\|El-Gohary, Nadia S\|El-Bendary, Eman R\|El-Kerdawy, Mohamed M
PMID:	26417284

1846.
Journal:	Biomedicines. 2014 Nov 25;2(4):345-358.
Title:	Role of HGF-MET Signaling in Primary and Acquired Resistance to Targeted Therapies in Cancer.
Author:	Della Corte, Carminia Maria\|Fasano, Morena\|Papaccio, Federica\|Ciardiello, Fortunato\|Morgillo, Floriana
PMID:	28548075

1847.
Journal:	J Magn Reson Imaging. 2015 Feb;41(2):474-80.
Title:	Correlation of dynamic contrast-enhanced MRI perfusion parameters with angiogenesis and biologic aggressiveness of rectal cancer: Preliminary results.
Author:	Yeo, Dong-Myung\|Oh, Soon Nam\|Jung, Chan-Kwon\|Lee, Myung Ah\|Oh, Seong Taek\|Rha, Sung Eun\|Jung, Seung Eun\|Byun, Jae Young\|Gall, Peter\|Son, Yohan
PMID:	24375840

1848.
Journal:	Int J Cancer. 2015 Feb 1;136(3):493-502.
Title:	Molecular therapy of colorectal cancer: progress and future directions.
Author:	Weng, Wenhao\|Feng, Junlan\|Qin, Huanlong\|Ma, Yanlei
PMID:	24420815

1849.
Journal:	Oncogene. 2015 Jan 22;34(4):531-6.
Title:	A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.
Author:	Bajpe, P K\|Prahallad, A\|Horlings, H\|Nagtegaal, I\|Beijersbergen, R\|Bernards, R
PMID:	24469059

1850.
Journal:	J Enzyme Inhib Med Chem. 2015 Feb;30(1):160-5.
Title:	Structure-based drug design and biological evaluation of 2-acetamidobenzothiazole derivative as EGFR kinase inhibitor.
Author:	Gabr, Moustafa T\|El-Gohary, Nadia S\|El-Bendary, Eman R\|El-Kerdawy, Mohamed M
PMID:	24601650

1851.
Journal:	Int J Cancer. 2015 Jan 1;136(1):83-90.
Title:	Role of NRAS mutations as prognostic and predictive markers in metastatic colorectal cancer.
Author:	Schirripa, Marta\|Cremolini, Chiara\|Loupakis, Fotios\|Morvillo, Manfredi\|Bergamo, Francesca\|Zoratto, Federica\|Salvatore, Lisa\|Antoniotti, Carlotta\|Marmorino, Federica\|Sensi, Elisa\|Lupi, Cristiana\|Fontanini, Gabriella\|De Gregorio, Veronica\|Giannini, Riccardo
PMID:	24806288

1852.
Journal:	Ann Surg Oncol. 2015 Jan;22(1):187-94.
Title:	KRAS mutation is associated with worse prognosis in stage III or high-risk stage II colon cancer patients treated with adjuvant FOLFOX.
Author:	Lee, Dae-Won\|Kim, Kyung Ju\|Han, Sae-Won\|Lee, Hyun Jung\|Rhee, Ye Young\|Bae, Jeong Mo\|Cho, Nam-Yun\|Lee, Kyung-Hun\|Kim, Tae-Yong\|Oh, Do-Youn\|Im, Seock-Ah\|Bang, Yung-Jue\|Jeong, Seung-Yong\|Park, Kyu Joo\|Park, Jae-Gahb\|Kang, Gyeong Hoon\|Kim, Tae-You
PMID:	24889488

1853.
Journal:	Pharmacogenomics J. 2015 Feb;15(1):77-83.
Title:	EGFR ligands and DNA repair genes: genomic predictors of complete response after capecitabine-based chemoradiotherapy in locally advanced rectal cancer.
Author:	Sebio, A\|Salazar, J\|Paez, D\|Berenguer-Llergo, A\|Del Rio, E\|Tobena, M\|Martin-Richard, M\|Sullivan, I\|Targarona, E\|Balart, J\|Baiget, M\|Barnadas, A
PMID:	25026457

1854.
Journal:	Clin Cancer Res. 2015 Mar 1;21(5):1087-97.
Title:	Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy.
Author:	Laurent-Puig, Pierre\|Pekin, Deniz\|Normand, Corinne\|Kotsopoulos, Steve K\|Nizard, Philippe\|Perez-Toralla, Karla\|Rowell, Rachel\|Olson, Jeff\|Srinivasan, Preethi\|Le Corre, Delphine\|Hor, Thevy\|El Harrak, Zakaria\|Li, Xinyu\|Link, Darren R\|Bouche, Olivier\|Emile, J
PMID:	25248381

1855.
Journal:	Mol Carcinog. 2015 Nov;54(11):1442-50.
Title:	MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.
Author:	Ress, Anna Lena\|Stiegelbauer, Verena\|Winter, Elke\|Schwarzenbacher, Daniela\|Kiesslich, Tobias\|Lax, Sigurd\|Jahn, Stefan\|Deutsch, Alexander\|Bauernhofer, Thomas\|Ling, Hui\|Samonigg, Hellmut\|Gerger, Armin\|Hoefler, Gerald\|Pichler, Martin
PMID:	25256312

1856.
Journal:	J Clin Pathol. 2015 Jan;68(1):83-5.
Title:	KRAS mutation status impacts diagnosis and treatment decision in a patient with two colon tumours: a case report.
Author:	Li, Xiaodong\|Pezeshkpour, G\|Phan, Ryan T
PMID:	25313410

1857.
Journal:	Tumour Biol. 2015 Feb;36(2):1091-7.
Title:	Combine MEK inhibition with PI3K/mTOR inhibition exert inhibitory tumor growth effect on KRAS and PIK3CA mutation CRC xenografts due to reduced expression of VEGF and matrix metallopeptidase-9.
Author:	E, Jifu\|Xing, Junjie\|Gong, Haifeng\|He, Jian\|Zhang, Wei
PMID:	25326806

1858.
Journal:	Tumour Biol. 2015 Feb;36(2):1129-33.
Title:	Nrdp1 inhibits metastasis of colorectal cancer cells by EGFR signaling-dependent MMP7 modulation.
Author:	Jiang, Yongsheng\|Sun, Shaochuan\|Liu, Guoqin\|Yan, Bing\|Niu, Jun
PMID:	25330950

1859.
Journal:	J Appl Genet. 2015 May;56(2):185-92.
Title:	Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer.
Author:	Szmida, Elzbieta\|Karpinski, Pawel\|Leszczynski, Przemyslaw\|Sedziak, Tomasz\|Kielan, Wojciech\|Ostasiewicz, Pawel\|Sasiadek, Maria M
PMID:	25366420

1860.
Journal:	Clin Transl Oncol. 2015 Apr;17(4):264-73.
Title:	Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology.
Author:	Garcia-Alfonso, P\|Garcia-Foncillas, J\|Salazar, R\|Perez-Segura, P\|Garcia-Carbonero, R\|Musulen-Palet, E\|Cuatrecasas, M\|Landolfi, S\|Ramon Y Cajal, S\|Navarro, S
PMID:	25373533

1861.
Journal:	J Clin Pathol. 2015 Jan;68(1):64-8.
Title:	Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients.
Author:	Malapelle, Umberto\|Vigliar, Elena\|Sgariglia, Roberta\|Bellevicine, Claudio\|Colarossi, Lorenzo\|Vitale, Domenico\|Pallante, Pierlorenzo\|Troncone, Giancarlo
PMID:	25378536

1862.
Journal:	J Interferon Cytokine Res. 2015 Apr;35(4):273-80.
Title:	Deficiency of interferon-gamma or its receptor promotes colorectal cancer development.
Author:	Wang, Lu\|Wang, Yan\|Song, Zhiyu\|Chu, Jiahui\|Qu, Xianjun
PMID:	25383957

1863.
Journal:	Mol Pharm. 2015 Jan 5;12(1):10-7.
Title:	Serial in vivo imaging using a fluorescence probe allows identification of tumor early response to cetuximab immunotherapy.
Author:	Ma, Teng\|Liu, Hao\|Sun, Xianlei\|Gao, Liquan\|Shi, Jiyun\|Zhao, Huiyun\|Jia, Bing\|Wang, Fan\|Liu, Zhaofei
PMID:	25397907

1864.
Journal:	Expert Rev Pharmacoecon Outcomes Res. 2015 Feb;15(1):81-100.
Title:	The use of EGFR inhibitors in colorectal cancer: is it clinically efficacious and cost-effective?
Author:	Lien, Kelly\|Berry, Scott\|Ko, Yoo-Joung\|Chan, Kelvin K W
PMID:	25400031

1865.
Journal:	Genes Chromosomes Cancer. 2015 Feb;54(2):110-21.
Title:	Heterogeneous DNA methylation contributes to tumorigenesis through inducing the loss of coexpression connectivity in colorectal cancer.
Author:	Wang, Quan\|Jia, Peilin\|Cheng, Feixiong\|Zhao, Zhongming
PMID:	25407423

1866.
Journal:	Oncologist. 2015 Jan;20(1):14-8.
Title:	Cost estimates and economic implications of expanded RAS testing in metastatic colorectal cancer.
Author:	Kircher, Sheetal M\|Mohindra, Nisha\|Nimeiri, Halla
PMID:	25410095

1867.
Journal:	Br J Cancer. 2015 Jan 20;112(2):313-8.
Title:	Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer.
Author:	Augustine, T A\|Baig, M\|Sood, A\|Budagov, T\|Atzmon, G\|Mariadason, J M\|Aparo, S\|Maitra, R\|Goel, S
PMID:	25412235

1868.
Journal:	Target Oncol. 2015 Sep;10(3):415-21.
Title:	Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping?
Author:	Allard, M A\|Saffroy, R\|de la Maisonneuve, P Bouvet\|Ricca, L\|Bosselut, N\|Hamelin, J\|Lecorche, E\|Bejarano, M A\|Innominato, P\|Sebagh, M\|Adam, R\|Morere, J F\|Lemoine, A
PMID:	25420993

1869.
Journal:	J Natl Cancer Inst. 2014 Nov 24;107(1):364.
Title:	Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer.
Author:	Kobold, Sebastian\|Steffen, Julius\|Chaloupka, Michael\|Grassmann, Simon\|Henkel, Jonas\|Castoldi, Raffaella\|Zeng, Yi\|Chmielewski, Markus\|Schmollinger, Jan C\|Schnurr, Max\|Rothenfusser, Simon\|Schendel, Dolores J\|Abken, Hinrich\|Sustmann, Claudio\|Niederfellner, G
PMID:	25424197

1870.
Journal:	Surg Oncol Clin N Am. 2015 Jan;24(1):199-214.
Title:	Integrating systemic and surgical approaches to treating metastatic colorectal cancer.
Author:	Mi, Kaihong\|Kalady, Matthew F\|Quintini, Cristiano\|Khorana, Alok A
PMID:	25444476

1871.
Journal:	J Immunol Methods. 2015 Jan;416:59-68.
Title:	Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories.
Author:	Zhou, Jerry\|Belov, Larissa\|Chapuis, Pierre\|Chan, Charles\|Armstrong, Nicola\|Kaufman, Kimberley L\|Solomon, Michael J\|Clarke, Stephen J\|Christopherson, Richard I
PMID:	25445327

1872.
Journal:	Exp Mol Pathol. 2015 Jun;98(3):375-81.
Title:	Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR.
Author:	Wang, Huijuan\|Yang, Bobo\|Geng, Tingting\|Li, Bin\|Dai, Penggao\|Chen, Chao
PMID:	25445497

1873.
Journal:	Metabolism. 2015 Mar;64(3 Suppl 1):S16-21.
Title:	Biomarkers for personalized oncology: recent advances and future challenges.
Author:	Kalia, Madhu
PMID:	25468140

1874.
Journal:	Ann Surg Oncol. 2015 Aug;22(8):2640-8.
Title:	Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer.
Author:	Igarashi, Hisayoshi\|Kurihara, Hiroyoshi\|Mitsuhashi, Kei\|Ito, Miki\|Okuda, Hiroyuki\|Kanno, Shinichi\|Naito, Takafumi\|Yoshii, Shinji\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hasegawa, Tadashi\|Sukawa, Yasutaka\|Adachi, Yasushi\|Okita, Kenji\|Hirata, Koichi\|Imamura, Yu\|B
PMID:	25472647

1875.
Journal:	Lasers Surg Med. 2015 Jan;47(1):40-9.
Title:	In vivo molecular mapping of the tumor microenvironment in an azoxymethane-treated mouse model of colon carcinogenesis.
Author:	Leung, Sarah J\|Rice, Photini S\|Barton, Jennifer K
PMID:	25487746

1876.
Journal:	Cytometry B Clin Cytom. 2015 Mar;88(2):136-44.
Title:	Isolating epidermal growth factor receptor overexpressing carcinoma cells from human whole blood by bio-ferrography.
Author:	Levi, Ofer\|Shapira, Assaf\|Tal, Baruch\|Benhar, Itai\|Eliaz, Noam
PMID:	25491065

1877.
Journal:	Carcinogenesis. 2015 Mar;36(3):338-45.
Title:	MicroRNA-7 expression in colorectal cancer is associated with poor prognosis and regulates cetuximab sensitivity via EGFR regulation.
Author:	Suto, Toshinaga\|Yokobori, Takehiko\|Yajima, Reina\|Morita, Hiroki\|Fujii, Takaaki\|Yamaguchi, Satoru\|Altan, Bolag\|Tsutsumi, Souichi\|Asao, Takayuki\|Kuwano, Hiroyuki
PMID:	25503932

1878.
Journal:	Anticancer Drugs. 2015 Apr;26(4):371-8.
Title:	Effect of KRAS exon 2 mutations on antitumor activity of afatinib and gefitinib.
Author:	Gamba, Sebastian\|Camaj, Peter\|Heinemann, Volker\|Laubender, Rudiger P\|Wang, Yan\|Zhao, Yue\|Stintzing, Sebastian\|Giessen, Clemens\|Boeck, Stefan\|Haertl, Christoph\|Bruns, Christiane J\|Modest, Dominik P
PMID:	25514114

1879.
Journal:	Pharmacogenomics J. 2015 Aug;15(4):354-62.
Title:	Distinct gene expression profiles of proximal and distal colorectal cancer: implications for cytotoxic and targeted therapy.
Author:	Maus, M K H\|Hanna, D L\|Stephens, C L\|Astrow, S H\|Yang, D\|Grimminger, P P\|Loupakis, F\|Hsiang, J H\|Zeger, G\|Wakatsuki, T\|Barzi, A\|Lenz, H-J
PMID:	25532759

1880.
Journal:	Tumour Biol. 2015 May;36(5):3471-82.
Title:	Electrolyte disorders assessment in solid tumor patients treated with anti-EGFR monoclonal antibodies: a pooled analysis of 25 randomized clinical trials.
Author:	Wang, Qiaoli\|Qi, Yuexiao\|Zhang, Di\|Gong, Caifeng\|Yao, Anqi\|Xiao, Yi\|Yang, Jie\|Zhou, Fuxiang\|Zhou, Yunfeng
PMID:	25542231

1881.
Journal:	Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):839-44.
Title:	Examination of HER3 targeting in cancer using monoclonal antibodies.
Author:	Gaborit, Nadege\|Abdul-Hai, Ali\|Mancini, Maicol\|Lindzen, Moshit\|Lavi, Sara\|Leitner, Orith\|Mounier, Lucile\|Chentouf, Myriam\|Dunoyer, Sai\|Ghosh, Manjusha\|Larbouret, Christel\|Chardes, Thierry\|Bazin, Herve\|Pelegrin, Andre\|Sela, Michael\|Yarden, Yosef
PMID:	25564668

1882.
Journal:	PLoS One. 2015 Jan 8;10(1):e0115672.
Title:	KRAS mutation analysis by PCR: a comparison of two methods.
Author:	Bolton, Louise\|Reiman, Anne\|Lucas, Katie\|Timms, Judith\|Cree, Ian A
PMID:	25568935

1883.
Journal:	Oncol Rep. 2015 Mar;33(3):1161-70.
Title:	Icotinib hydrochloride enhances the effect of radiotherapy by affecting DNA repair in colorectal cancer cells.
Author:	Ma, Hong\|Bi, Jianping\|Liu, Tao\|Ke, Yang\|Zhang, Sheng\|Zhang, Tao
PMID:	25572529

1884.
Journal:	Med Oncol. 2015 Feb;32(2):456.
Title:	Prognostic factors for survival with bevacizumab-based therapy in colorectal cancer patients: a systematic review and pooled analysis of 11,585 patients.
Author:	Petrelli, Fausto\|Coinu, Andrea\|Cabiddu, Mary\|Borgonovo, Karen\|Lonati, Veronica\|Ghilardi, Mara\|Barni, Sandro
PMID:	25572811

1885.
Journal:	Clin Cancer Res. 2015 Apr 1;21(7):1583-90.
Title:	Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation.
Author:	Bohanes, Pierre\|Rankin, Cathryn J\|Blanke, Charles D\|Winder, Thomas\|Ulrich, Cornelia M\|Smalley, Stephen R\|Rich, Tyvin A\|Martensen, James A\|Benson, Al B 3rd\|Mayer, Robert J\|Cripps, Christine M\|Danenberg, Kathleen\|Makar, Karen W\|Zhang, Wu\|Benedetti, Jacqueli
PMID:	25589620

1886.
Journal:	Clin Cancer Res. 2015 Mar 15;21(6):1313-20.
Title:	Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients.
Author:	Yaeger, Rona\|Cercek, Andrea\|O'Reilly, Eileen M\|Reidy, Diane L\|Kemeny, Nancy\|Wolinsky, Tamar\|Capanu, Marinela\|Gollub, Marc J\|Rosen, Neal\|Berger, Michael F\|Lacouture, Mario E\|Vakiani, Efsevia\|Saltz, Leonard B
PMID:	25589621

1887.
Journal:	Clin Cancer Res. 2015 Mar 15;21(6):1383-94.
Title:	Antibody-mediated delivery of anti-KRAS-siRNA in vivo overcomes therapy resistance in colon cancer.
Author:	Baumer, Sebastian\|Baumer, Nicole\|Appel, Neele\|Terheyden, Lisa\|Fremerey, Julia\|Schelhaas, Sonja\|Wardelmann, Eva\|Buchholz, Frank\|Berdel, Wolfgang E\|Muller-Tidow, Carsten
PMID:	25589625

1888.
Journal:	Int J Med Sci. 2015 Jan 1;12(2):92-9.
Title:	Syndecan-1 expression is associated with tumor size and EGFR expression in colorectal carcinoma: a clinicopathological study of 230 cases.
Author:	Kim, Su Young\|Choi, Eun Ji\|Yun, Jeong A\|Jung, Eun Sun\|Oh, Seung Taek\|Kim, Jun Gi\|Kang, Won Kyung\|Lee, Sung Hak
PMID:	25589885

1889.
Journal:	Cancer Res. 2015 Jan 15;75(2):245-9.
Title:	Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes.
Author:	Linnekamp, Janneke F\|Wang, Xin\|Medema, Jan Paul\|Vermeulen, Louis
PMID:	25593032

1890.
Journal:	Int J Pharm. 2015 Feb 20;479(2):364-73.
Title:	Epidermal growth factor receptor-targeted immunoliposomes for delivery of celecoxib to cancer cells.
Author:	Limasale, Yanuar Dwi Putra\|Tezcaner, Aysen\|Ozen, Can\|Keskin, Dilek\|Banerjee, Sreeparna
PMID:	25595386

1891.
Journal:	Acta Oncol. 2015 Apr;54(4):480-6.
Title:	HER3 expression in primary colorectal cancer including corresponding metastases in lymph node and liver.
Author:	Ledel, Frida\|Stenstedt, Kristina\|Hallstrom, Marja\|Ragnhammar, Peter\|Edler, David
PMID:	25601452

1892.
Journal:	Cancer Prev Res (Phila). 2015 Mar;8(3):222-30.
Title:	A phase IIa randomized, double-blind trial of erlotinib in inhibiting epidermal growth factor receptor signaling in aberrant crypt foci of the colorectum.
Author:	Gillen, Daniel L\|Meyskens, Frank L\|Morgan, Timothy R\|Zell, Jason A\|Carroll, Robert\|Benya, Richard\|Chen, Wen-Pin\|Mo, Allen\|Tucker, Chris\|Bhattacharya, Asmita\|Huang, Zhiliang\|Arcilla, Myra\|Wong, Vanessa\|Chung, Jinah\|Gonzalez, Rachel\|Rodriguez, Luz Maria\|Sza
PMID:	25604134

1893.
Journal:	Tumour Biol. 2015 Jun;36(6):4301-8.
Title:	TIMP-1 and CEA as biomarkers in third-line treatment with irinotecan and cetuximab for metastatic colorectal cancer.
Author:	Spindler, Karen-Lise Garm\|Christensen, Ib Jarle\|Nielsen, Hans Jorgen\|Jakobsen, Anders\|Brunner, Nils
PMID:	25608838

1894.
Journal:	J Clin Pathol. 2015 Apr;68(4):265-9.
Title:	KRAS mutant allele-specific imbalance (MASI) assessment in routine samples of patients with metastatic colorectal cancer.
Author:	Malapelle, Umberto\|Sgariglia, Roberta\|De Stefano, Alfonso\|Bellevicine, Claudio\|Vigliar, Elena\|de Biase, Dario\|Sepe, Romina\|Pallante, Pierlorenzo\|Carlomagno, Chiara\|Tallini, Giovanni\|Troncone, Giancarlo
PMID:	25609577

1895.
Journal:	J Colloid Interface Sci. 2015 May 1;445:151-160.
Title:	Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery.
Author:	She, Xiaodong\|Chen, Lijue\|Velleman, Leonora\|Li, Chengpeng\|Zhu, Haijin\|He, Canzhong\|Wang, Tao\|Shigdar, Sarah\|Duan, Wei\|Kong, Lingxue
PMID:	25617610

1896.
Journal:	Sci Rep. 2015 Jan 27;5:8013.
Title:	Systems approach for the selection of micro-RNAs as therapeutic biomarkers of anti-EGFR monoclonal antibody treatment in colorectal cancer.
Author:	Deyati, Avisek\|Bagewadi, Shweta\|Senger, Philipp\|Hofmann-Apitius, Martin\|Novac, Natalia
PMID:	25622824

1897.
Journal:	Clin Cancer Res. 2015 May 1;21(9):2157-66.
Title:	Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer.
Author:	Arena, Sabrina\|Bellosillo, Beatriz\|Siravegna, Giulia\|Martinez, Alejandro\|Canadas, Israel\|Lazzari, Luca\|Ferruz, Noelia\|Russo, Mariangela\|Misale, Sandra\|Gonzalez, Iria\|Iglesias, Mar\|Gavilan, Elena\|Corti, Giorgio\|Hobor, Sebastijan\|Crisafulli, Giovanni\|Salido
PMID:	25623215

1898.
Journal:	Ann Oncol. 2015 Apr;26(4):731-6.
Title:	Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment.
Author:	Morelli, M P\|Overman, M J\|Dasari, A\|Kazmi, S M A\|Mazard, T\|Vilar, E\|Morris, V K\|Lee, M S\|Herron, D\|Eng, C\|Morris, J\|Kee, B K\|Janku, F\|Deaton, F L\|Garrett, C\|Maru, D\|Diehl, F\|Angenendt, P\|Kopetz, S
PMID:	25628445

1899.
Journal:	Sci Transl Med. 2015 Jan 28;7(272):272ra12.
Title:	IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies.
Author:	Zanella, Eugenia R\|Galimi, Francesco\|Sassi, Francesco\|Migliardi, Giorgia\|Cottino, Francesca\|Leto, Simonetta M\|Lupo, Barbara\|Erriquez, Jessica\|Isella, Claudio\|Comoglio, Paolo M\|Medico, Enzo\|Tejpar, Sabine\|Budinska, Eva\|Trusolino, Livio\|Bertotti, Andrea
PMID:	25632036

1900.
Journal:	BMC Cancer. 2015 Jan 31;15:26.
Title:	Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium.
Author:	Tops, Bastiaan B J\|Normanno, Nicola\|Kurth, Henriette\|Amato, Eliana\|Mafficini, Andrea\|Rieber, Nora\|Le Corre, Delphine\|Rachiglio, Anna Maria\|Reiman, Anne\|Sheils, Orla\|Noppen, Christoph\|Lacroix, Ludovic\|Cree, Ian A\|Scarpa, Aldo\|Ligtenberg, Marjolijn J L\|Laur
PMID:	25637035

1901.
Journal:	Sci Rep. 2015 Feb 2;5:8065.
Title:	Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases.
Author:	Mao, Chen\|Wu, Xin-Yin\|Yang, Zu-Yao\|Threapleton, Diane Erin\|Yuan, Jin-Qiu\|Yu, Yuan-Yuan\|Tang, Jin-Ling
PMID:	25639985

1902.
Journal:	Oncologist. 2015 Mar;20(3):257-62.
Title:	External quality assessment unravels interlaboratory differences in quality of RAS testing for anti-EGFR therapy in colorectal cancer.
Author:	Tack, Veronique\|Ligtenberg, Marjolijn J L\|Tembuyser, Lien\|Normanno, Nicola\|Vander Borght, Sara\|Han van Krieken, J\|Dequeker, Elisabeth M C
PMID:	25657200

1903.
Journal:	Curr Gastroenterol Rep. 2015 Feb;17(2):431.
Title:	Molecular markers predictive of chemotherapy response in colorectal cancer.
Author:	Shiovitz, Stacey\|Grady, William M
PMID:	25663616

1904.
Journal:	Oncol Lett. 2015 Mar;9(3):1432-1438.
Title:	EGFR methylation and outcome of patients with advanced colorectal cancer treated with cetuximab.
Author:	Chiadini, Elisa\|Scarpi, Emanuela\|Passardi, Alessandro\|Calistri, Daniele\|Valgiusti, Martina\|Saragoni, Luca\|Zoli, Wainer\|Amadori, Dino\|Ulivi, Paola
PMID:	25663927

1905.
Journal:	Clin Colorectal Cancer. 2015 Jun;14(2):81-90.
Title:	Role of first-line anti-epidermal growth factor receptor therapy compared with anti-vascular endothelial growth factor therapy in advanced colorectal cancer: a meta-analysis of randomized clinical trials.
Author:	Khattak, Muhammad A\|Martin, Hilary\|Davidson, Andrew\|Phillips, Michael
PMID:	25666296

1906.
Journal:	Eur J Cancer. 2015 Mar;51(5):587-94.
Title:	Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: a meta-analysis.
Author:	Pietrantonio, Filippo\|Petrelli, Fausto\|Coinu, Andrea\|Di Bartolomeo, Maria\|Borgonovo, Karen\|Maggi, Claudia\|Cabiddu, Mary\|Iacovelli, Roberto\|Bossi, Ilaria\|Lonati, Veronica\|Ghilardi, Mara\|de Braud, Filippo\|Barni, Sandro
PMID:	25673558

1907.
Journal:	Cancer Discov. 2015 Apr;5(4):358-67.
Title:	Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.
Author:	Ahronian, Leanne G\|Sennott, Erin M\|Van Allen, Eliezer M\|Wagle, Nikhil\|Kwak, Eunice L\|Faris, Jason E\|Godfrey, Jason T\|Nishimura, Koki\|Lynch, Kerry D\|Mermel, Craig H\|Lockerman, Elizabeth L\|Kalsy, Anuj\|Gurski, Joseph M Jr\|Bahl, Samira\|Anderka, Kristin\|Green,
PMID:	25673644

1908.
Journal:	Appl Immunohistochem Mol Morphol. 2015 Feb;23(2):e4-7.
Title:	Direct correlation between double K-RAS mutation and mucinous carcinoma. A case report.
Author:	Pacini, Luca\|Bastianelli, Daniela\|Ponti, Donatella\|Rosa, Paolo\|Petrozza, Vincenzo\|Giannini, Giuseppe\|Ragona, Giuseppe\|Calogero, Antonella
PMID:	25675084

1909.
Journal:	MAbs. 2015;7(2):440-50.
Title:	Generation and characterization of a target-selectively activated antibody against epidermal growth factor receptor with enhanced anti-tumor potency.
Author:	Yang, Yun\|Guo, Qingcheng\|Xia, Mao\|Li, Yantao\|Peng, Xiaoyun\|Liu, Tao\|Tong, Xin\|Xu, Jin\|Guo, Huaizu\|Qian, Weizhu\|Hou, Sheng\|Dai, Jianxin\|Wang, Hao\|Liu, Rong\|Guo, Yajun
PMID:	25679409

1910.
Journal:	World J Gastroenterol. 2015 Feb 14;21(6):1749-58.
Title:	Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia.
Author:	Isidro, Raymond A\|Cruz, Myrella L\|Isidro, Angel A\|Baez, Axel\|Arroyo, Axel\|Gonzalez-Marques, William A\|Gonzalez-Keelan, Carmen\|Torres, Esther A\|Appleyard, Caroline B
PMID:	25684939

1911.
Journal:	Curr Oncol Rep. 2015 Mar;17(3):434.
Title:	The neoadjuvant treatment of rectal cancer: a review.
Author:	Nussbaum, Nathan\|Altomare, Ivy
PMID:	25691086

1912.
Journal:	Cancer Biol Ther. 2015;16(3):383-91.
Title:	Heterozygous deletion of ATG5 in Apc(Min/+) mice promotes intestinal adenoma growth and enhances the antitumor efficacy of interferon-gamma.
Author:	Wang, Lu\|Wang, Yan\|Lu, Yuyin\|Zhang, Qianyun\|Qu, Xianjun
PMID:	25695667

1913.
Journal:	Cell Cycle. 2015;14(8):1252-9.
Title:	Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics.
Author:	Kato, Shumei\|Schwaederle, Maria\|Daniels, Gregory A\|Piccioni, David\|Kesari, Santosh\|Bazhenova, Lyudmila\|Shimabukuro, Kelly\|Parker, Barbara A\|Fanta, Paul\|Kurzrock, Razelle
PMID:	25695927

1914.
Journal:	Int J Cancer. 2015 Sep 15;137(6):1467-74.
Title:	Circulating tumor cells as a longitudinal biomarker in patients with advanced chemorefractory, RAS-BRAF wild-type colorectal cancer receiving cetuximab or panitumumab.
Author:	Musella, Valeria\|Pietrantonio, Filippo\|Di Buduo, Eleonora\|Iacovelli, Roberto\|Martinetti, Antonia\|Sottotetti, Elisa\|Bossi, Ilaria\|Maggi, Claudia\|Di Bartolomeo, Maria\|de Braud, Filippo\|Daidone, Maria Grazia\|Cappelletti, Vera
PMID:	25704501

1915.
Journal:	J Cell Physiol. 2015 Sep;230(9):2281-98.
Title:	Nexavar/Stivarga and viagra interact to kill tumor cells.
Author:	Tavallai, Mehrad\|Hamed, Hossein A\|Roberts, Jane L\|Cruickshanks, Nichola\|Chuckalovcak, John\|Poklepovic, Andrew\|Booth, Laurence\|Dent, Paul
PMID:	25704960

1916.
Journal:	Analyst. 2015 Apr 21;140(8):2747-54.
Title:	KRAS mutation screening by chip-based DNA hybridization--a further step towards personalized oncology.
Author:	Steinbach, Christine\|Steinbrucker, Carolin\|Pollok, Sibyll\|Walther, Katharina\|Clement, Joachim H\|Chen, Yuan\|Petersen, Iver\|Cialla-May, Dana\|Weber, Karina\|Popp, Jurgen
PMID:	25706807

1917.
Journal:	Cancer Res. 2015 Apr 15;75(8):1560-6.
Title:	Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Author:	Nunes, Manoel\|Vrignaud, Patricia\|Vacher, Sophie\|Richon, Sophie\|Lievre, Astrid\|Cacheux, Wulfran\|Weiswald, Louis-Bastien\|Massonnet, Gerald\|Chateau-Joubert, Sophie\|Nicolas, Andre\|Dib, Colette\|Zhang, Weidong\|Watters, James\|Bergstrom, Donald\|Roman-Roman, Sergi
PMID:	25712343

1918.
Journal:	Mol Cancer Res. 2015 Jun;13(6):1003-8.
Title:	AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.
Author:	Hechtman, Jaclyn F\|Sadowska, Justyna\|Huse, Jason T\|Borsu, Laetitia\|Yaeger, Rona\|Shia, Jinru\|Vakiani, Efsevia\|Ladanyi, Marc\|Arcila, Maria E
PMID:	25714871

1919.
Journal:	Br J Cancer. 2015 Mar 17;112(6):963-70.
Title:	Correlation of extended RAS and PIK3CA gene mutation status with outcomes from the phase III AGITG MAX STUDY involving capecitabine alone or in combination with bevacizumab plus or minus mitomycin C in advanced colorectal cancer.
Author:	Price, T J\|Bruhn, M A\|Lee, C K\|Hardingham, J E\|Townsend, A R\|Mann, K P\|Simes, J\|Weickhardt, A\|Wrin, J W\|Wilson, K\|Gebski, V\|Van Hazel, G\|Robinson, B\|Cunningham, D\|Tebbutt, N C
PMID:	25742472

1920.
Journal:	Gan To Kagaku Ryoho. 2015 Feb;42(2):237-9.
Title:	[A successful multimodality therapy for a case of recurrent rectal cancer with KRAS mutation].
Author:	Watanabe, Ayako\|Inada, Ryo\|Nagasaka, Takeshi\|Yagi, Tomohiko\|Matsumoto, Hijiri\|Toshima, Toshiaki\|Mori, Yoshiko\|Kondo, Yoshitaka\|Kishimoto, Hiroyuki\|Fujiwara, Toshiyoshi
PMID:	25743147

1921.
Journal:	Oncogene. 2015 Dec 3;34(49):5971-82.
Title:	An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis.
Author:	Zhu, G\|Fan, Z\|Ding, M\|Zhang, H\|Mu, L\|Ding, Y\|Zhang, Y\|Jia, B\|Chen, L\|Chang, Z\|Wu, W
PMID:	25746002

1922.
Journal:	Anticancer Res. 2015 Mar;35(3):1683-9.
Title:	Circulating hepatocyte growth factor is correlated with resistance to cetuximab in metastatic colorectal cancer.
Author:	Yonesaka, Kimio\|Satoh, Taroh\|Ueda, Shinya\|Yoshida, Takeshi\|Takeda, Masayuki\|Shimizu, Toshio\|Okamoto, Isamu\|Nishio, Kazuto\|Tamura, Takao\|Nakagawa, Kazuhiko
PMID:	25750328

1923.
Journal:	Mol Ther Nucleic Acids. 2015 Mar 10;4:e231.
Title:	Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer.
Author:	Hiraki, Masayuki\|Nishimura, Junichi\|Takahashi, Hidekazu\|Wu, Xin\|Takahashi, Yusuke\|Miyo, Masaaki\|Nishida, Naohiro\|Uemura, Mamoru\|Hata, Taishi\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Soh, Jae-Won\|Doki, Yuichiro\|Mori, Masaki\|Yamamoto, Hirofumi
PMID:	25756961

1924.
Journal:	J Mol Biol. 2015 May 22;427(10):1934-48.
Title:	LRIG1 extracellular domain: structure and function analysis.
Author:	Xu, Yibin\|Soo, Priscilla\|Walker, Francesca\|Zhang, Hui Hua\|Redpath, Nicholas\|Tan, Chin Wee\|Nicola, Nicos A\|Adams, Timothy E\|Garrett, Thomas P\|Zhang, Jian-Guo\|Burgess, Antony W
PMID:	25765764

1925.
Journal:	Curr Opin Oncol. 2015 May;27(3):276-81.
Title:	B-type proto-oncogene-mutated tumors of colon cancer: promising therapeutic approaches.
Author:	Temraz, Sally\|Alameddine, Raafat\|Shamseddine, Ali
PMID:	25774859

1926.
Journal:	J BUON. 2015 Jan-Feb;20(1):128-35.
Title:	KRAS discordance between primary and metastatic tumor in patients with metastatic colorectal carcinoma.
Author:	Siyar Ekinci, Ahmet\|Demirci, Umut\|Cakmak Oksuzoglu, Berna\|Ozturk, Ayse\|Esbah, Onur\|Ozatli, Tahsin\|Celik, Burcin\|Budakoglu, Burcin\|Turker, Ibrahim\|Bal, Oznur\|Turan, Nedim
PMID:	25778307

1927.
Journal:	World J Gastroenterol. 2015 Mar 14;21(10):2871-4.
Title:	Targeted therapy in first line treatment of RAS wild type colorectal cancer.
Author:	Formica, Vincenzo\|Roselli, Mario
PMID:	25780283

1928.
Journal:	J Invest Dermatol. 2015 Jul;135(7):1863-1872.
Title:	MITF Modulates Therapeutic Resistance through EGFR Signaling.
Author:	Ji, Zhenyu\|Erin Chen, Yiyin\|Kumar, Raj\|Taylor, Michael\|Jenny Njauw, Ching-Ni\|Miao, Benchun\|Frederick, Dennie T\|Wargo, Jennifer A\|Flaherty, Keith T\|Jonsson, Goran\|Tsao, Hensin
PMID:	25789707

1929.
Journal:	Cancer Sci. 2015 Mar;106(3):324-7.
Title:	Japanese Society of Medical Oncology Clinical Guidelines: RAS (KRAS/NRAS) mutation testing in colorectal cancer patients.
Author:	Taniguchi, Hiroya\|Yamazaki, Kentaro\|Yoshino, Takayuki\|Muro, Kei\|Yatabe, Yasushi\|Watanabe, Toshiaki\|Ebi, Hiromichi\|Ochiai, Atsushi\|Baba, Eishi\|Tsuchihara, Katsuya
PMID:	25800101

1930.
Journal:	Genes Dis. 2015 Mar;2(1):4-12.
Title:	Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer.
Author:	Knickelbein, Kyle\|Zhang, Lin
PMID:	25815366

1931.
Journal:	Database (Oxford). 2015 Mar 27;2015. pii: bav015.
Title:	Colorectal cancer drug target prediction using ontology-based inference and network analysis.
Author:	Tao, Cui\|Sun, Jingchun\|Zheng, W Jim\|Chen, Junjie\|Xu, Hua
PMID:	25818893

1932.
Journal:	Oncol Rep. 2015 Jun;33(6):2719-27.
Title:	Eprobe-mediated screening system for somatic mutations in the KRAS locus.
Author:	Atsumi, Jun\|Hanami, Takeshi\|Enokida, Yasuaki\|Ogawa, Hiroomi\|Delobel, Diane\|Mitani, Yasumasa\|Kimura, Yasumasa\|Soma, Takahiro\|Tagami, Michihira\|Takase, Yoshiaki\|Ichihara, Tatsuo\|Takeyoshi, Izumi\|Usui, Kengo\|Hayashizaki, Yoshihide\|Shimizu, Kimihiro
PMID:	25823645

1933.
Journal:	Rom J Morphol Embryol. 2015;56(1):175-81.
Title:	Histochemical and immunohistochemical evidence of tumor heterogeneity in colorectal cancer.
Author:	Zlatian, Ovidiu Mircea\|Comanescu, Maria Victoria\|Rosu, Alexandra Floriana\|Rosu, Lucica\|Cruce, Mihai\|Gaman, Alice Elena\|Calina, Cornelia Daniela\|Sfredel, Veronica
PMID:	25826503

1934.
Journal:	J Gastrointest Oncol. 2015 Apr;6(2):185-200.
Title:	Review of systemic therapies for locally advanced and metastatic rectal cancer.
Author:	Yaffee, Patrick\|Osipov, Arsen\|Tan, Carlyn\|Tuli, Richard\|Hendifar, Andrew
PMID:	25830038

1935.
Journal:	Clin Cancer Res. 2015 Apr 1;21(7):1505-7.
Title:	CCR 20th Anniversary commentary: in search of cetuximab's first indication-combination therapy with irinotecan in colorectal cancer.
Author:	Hicklin, Daniel J
PMID:	25833307

1936.
Journal:	World J Gastroenterol. 2015 Mar 28;21(12):3746-9.
Title:	Cetuximab and panitumumab in a patient with colon cancer and concomitant chronic skin disease: a potential beneficial effect on psoriasis vulgaris.
Author:	Okamoto, Ken\|Maeda, Hiromichi\|Shiga, Takeo\|Shiga, Mai\|Dabanaka, Ken\|Hanazaki, Kazuhiro\|Kobayashi, Michiya
PMID:	25834345

1937.
Journal:	Exp Mol Pathol. 2015 Jun;98(3):563-7.
Title:	KRAS gene mutation in a series of unselected colorectal carcinoma patients with prognostic morphological correlations: a pyrosequencing method improved by nested PCR.
Author:	de Macedo, Mariana Petaccia\|de Melo, Fernanda Machado\|Lisboa, Bianca Cristina Garcia\|Andrade, Louise D Brot\|de Souza Begnami, Maria Dirlei Ferreira\|Junior, Samuel Aguiar\|Ribeiro, Heber Salvador de Castro\|Soares, Fernando Augusto\|Carraro, Dirce Maria\|da Cu
PMID:	25835782

1938.
Journal:	Clin Cancer Res. 2015 Jul 1;21(13):2975-83.
Title:	Primary and Acquired Resistance of Colorectal Cancer to Anti-EGFR Monoclonal Antibody Can Be Overcome by Combined Treatment of Regorafenib with Cetuximab.
Author:	Napolitano, Stefania\|Martini, Giulia\|Rinaldi, Barbara\|Martinelli, Erika\|Donniacuo, Maria\|Berrino, Liberato\|Vitagliano, Donata\|Morgillo, Floriana\|Barra, Giusy\|De Palma, Raffaele\|Merolla, Francesco\|Ciardiello, Fortunato\|Troiani, Teresa
PMID:	25838391

1939.
Journal:	Cell Cycle. 2015;14(8):1129-30.
Title:	VEGF and dual-EGFR inhibition in colorectal cancer.
Author:	Falchook, Gerald S\|Kurzrock, Razelle
PMID:	25845022

1940.
Journal:	Ann Biol Clin (Paris). 2015 Mar-Apr;73(2):158-64.
Title:	[Accumulation of p53 protein and overexpression of the HER3 receptor in colorectal cancer].
Author:	Amsaguine, Siham\|El Mhaia, Sara\|Drissi, Houda\|Amer, Chrifa\|Ahallat, Mohammed\|El Amrani, Najat\|Radallah, Driss
PMID:	25847737

1941.
Journal:	Oncoscience. 2015 Feb 9;2(2):125-30.
Title:	RAS mutations vary between lesions in synchronous primary colorectal cancer: testing only one lesion is not sufficient to guide anti-EGFR treatment decisions.
Author:	de Macedo, Mariana Petaccia\|de Melo, Fernanda Machado\|Ribeiro, Julia da Silva\|de Mello, Celso Abdon Lopes\|de Souza Begnami, Maria Dirlei Ferreira\|Soares, Fernando Augusto\|Carraro, Dirce Maria\|da Cunha, Isabela Werneck
PMID:	25859555

1942.
Journal:	Clin Colorectal Cancer. 2015 Sep;14(3):154-61.
Title:	A Phase II Study of Sorafenib Combined With Cetuximab in EGFR-Expressing, KRAS-Mutated Metastatic Colorectal Cancer.
Author:	Do, Khanh\|Cao, Liang\|Kang, Zhigang\|Turkbey, Baris\|Lindenberg, Maria L\|Larkins, Erin\|Holkova, Beata\|Steinberg, Seth M\|Raffeld, Mark\|Peer, Cody J\|Figg, William D\|Eugeni, Michelle\|Jacobs, Paula\|Choyke, Peter\|Wright, John J\|Doroshow, James H\|Kummar, Shivaani
PMID:	25861837

1943.
Journal:	J Transl Med. 2015 Mar 28;13:101.
Title:	Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients.
Author:	Benvenuto, Monica\|Sileri, Pierpaolo\|Rossi, Piero\|Masuelli, Laura\|Fantini, Massimo\|Nanni, Monica\|Franceschilli, Luana\|Sconocchia, Giuseppe\|Lanzilli, Giulia\|Arriga, Roberto\|Faggioni, Giovanni\|Lista, Florigio\|Orlandi, Augusto\|Manzari, Vittorio\|Gaspari, Achil
PMID:	25889931

1944.
Journal:	Ann Nucl Med. 2015 Jul;29(6):535-42.
Title:	[(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study.
Author:	McKinley, Eliot T\|Watchmaker, Jennifer M\|Chakravarthy, A Bapsi\|Meyerhardt, Jeffrey A\|Engelman, Jeffrey A\|Walker, Ronald C\|Washington, M Kay\|Coffey, Robert J\|Manning, H Charles
PMID:	25899481

1945.
Journal:	J Surg Oncol. 2015 Jun;111(7):905-10.
Title:	Mutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancers.
Author:	Lan, Yuan-Tzu\|Jen-Kou, Lin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Lin, Chun-Chi\|Wang, Huann-Sheng\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Jiang, Jeng-Kai\|Chang, Shih-Ching
PMID:	25920435

1946.
Journal:	Glycobiology. 2015 Aug;25(8):855-68.
Title:	NEU3 activity enhances EGFR activation without affecting EGFR expression and acts on its sialylation levels.
Author:	Mozzi, Alessandra\|Forcella, Matilde\|Riva, Alice\|Difrancesco, Carlotta\|Molinari, Francesca\|Martin, Vittoria\|Papini, Nadia\|Bernasconi, Barbara\|Nonnis, Simona\|Tedeschi, Gabriella\|Mazzucchelli, Luca\|Monti, Eugenio\|Fusi, Paola\|Frattini, Milo
PMID:	25922362

1947.
Journal:	Nat Commun. 2015 Apr 30;6:7002.
Title:	The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Author:	Medico, Enzo\|Russo, Mariangela\|Picco, Gabriele\|Cancelliere, Carlotta\|Valtorta, Emanuele\|Corti, Giorgio\|Buscarino, Michela\|Isella, Claudio\|Lamba, Simona\|Martinoglio, Barbara\|Veronese, Silvio\|Siena, Salvatore\|Sartore-Bianchi, Andrea\|Beccuti, Marco\|Mottolese
PMID:	25926053

1948.
Journal:	Tumour Biol. 2015 Sep;36(10):7641-7.
Title:	MiR-497 promotes metastasis of colorectal cancer cells through Nrdp1 inhibition.
Author:	Jiang, Yongsheng\|Meng, Qinghua\|Qi, Jiaqin\|Shen, Haiyu\|Sun, Shaochuan
PMID:	25926384

1949.
Journal:	Mol Oncol. 2015 Aug;9(7):1434-46.
Title:	KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells.
Author:	Leiser, Dominic\|Medova, Michaela\|Mikami, Kei\|Nisa, Lluis\|Stroka, Deborah\|Blaukat, Andree\|Bladt, Friedhelm\|Aebersold, Daniel M\|Zimmer, Yitzhak
PMID:	25933688

1950.
Journal:	Int J Oncol. 2015 Jul;47(1):97-105.
Title:	A novel approach to detect KRAS/BRAF mutation for colon cancer: Highly sensitive simultaneous detection of mutations and simple pre-treatment without DNA extraction.
Author:	Suzuki, Shun-Ichi\|Matsusaka, Satoshi\|Hirai, Mitsuharu\|Shibata, Harumi\|Takagi, Koichi\|Mizunuma, Nobuyuki\|Hatake, Kiyohiko
PMID:	25936694

1951.
Journal:	J Transl Med. 2015 May 7;13:140.
Title:	Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab.
Author:	Giampieri, Riccardo\|Mandolesi, Alessandra\|Abouelkhair, Khaled M\|Loretelli, Cristian\|Del Prete, Michela\|Faloppi, Luca\|Maristella, Bianconi\|Ibrahim, Ezzeldin M\|Scarpelli, Marina\|Cascinu, Stefano\|Scartozzi, Mario
PMID:	25943333

1952.
Journal:	Cancer Immunol Res. 2015 Sep;3(9):1052-62.
Title:	Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody.
Author:	Stewart, Ross\|Morrow, Michelle\|Hammond, Scott A\|Mulgrew, Kathy\|Marcus, Danielle\|Poon, Edmund\|Watkins, Amanda\|Mullins, Stefanie\|Chodorge, Matthieu\|Andrews, John\|Bannister, David\|Dick, Emily\|Crawford, Nicola\|Parmentier, Julie\|Alimzhanov, Marat\|Babcook, John
PMID:	25943534

1953.
Journal:	Oncotarget. 2015 Jun 20;6(17):15681-9.
Title:	RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers.
Author:	Boleij, Annemarie\|Tops, Bastiaan B J\|Rombout, Paul D M\|Dequeker, Elizabeth M\|Ligtenberg, Marjolijn J L\|van Krieken, J Han
PMID:	25944693

1954.
Journal:	Clin Cancer Res. 2015 Aug 15;21(16):3695-704.
Title:	Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.
Author:	Bazzocco, Sarah\|Dopeso, Higinio\|Carton-Garcia, Fernando\|Macaya, Irati\|Andretta, Elena\|Chionh, Fiona\|Rodrigues, Paulo\|Garrido, Miriam\|Alazzouzi, Hafid\|Nieto, Rocio\|Sanchez, Alex\|Schwartz, Simo Jr\|Bilic, Josipa\|Mariadason, John M\|Arango, Diego
PMID:	25944804

1955.
Journal:	PLoS One. 2015 May 8;10(5):e0121891.
Title:	Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.
Author:	Sakai, Kazuko\|Tsurutani, Junji\|Yamanaka, Takeharu\|Yoneshige, Azusa\|Ito, Akihiko\|Togashi, Yosuke\|De Velasco, Marco A\|Terashima, Masato\|Fujita, Yoshihiko\|Tomida, Shuta\|Tamura, Takao\|Nakagawa, Kazuhiko\|Nishio, Kazuto
PMID:	25954997

1956.
Journal:	Cancer Discov. 2015 Jun;5(6):598-609.
Title:	Safety and Activity of the First-in-Class Sym004 Anti-EGFR Antibody Mixture in Patients with Refractory Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Patnaik, Amita\|Garcia-Carbonero, Rocio\|Cervantes, Andres\|Benavent, Marta\|Rosello, Susana\|Tops, Bastiaan B J\|van der Post, Rachel S\|Argiles, Guillem\|Skartved, Niels J O\|Hansen, Ulla H\|Hald, Rikke\|Pedersen, Mikkel W\|Kragh, Michael\|Horak,
PMID:	25962717

1957.
Journal:	Oncotarget. 2015 Jun 30;6(18):16059-68.
Title:	Correlation between tumor engraftment in patient-derived xenograft models and clinical outcomes in colorectal cancer patients.
Author:	Oh, Bo Young\|Lee, Woo Yong\|Jung, Sungwon\|Hong, Hye Kyung\|Nam, Do-Hyun\|Park, Yoon Ah\|Huh, Jung Wook\|Yun, Seong Hyeon\|Kim, Hee Cheol\|Chun, Ho-Kyung\|Cho, Yong Beom
PMID:	25965827

1958.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):560-74. eCollection 2015.
Title:	Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells.
Author:	Grunt, Thomas W\|Hebar, Alexandra\|Laffer, Sylvia\|Wagner, Renate\|Peter, Barbara\|Herrmann, Harald\|Graf, Alexandra\|Bilban, Martin\|Posch, Martin\|Hoermann, Gregor\|Mayerhofer, Matthias\|Eisenwort, Gregor\|Zielinski, Christoph C\|Selzer, Edgar\|Valent, Peter
PMID:	25973297

1959.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):674-88. eCollection 2015.
Title:	A specific KRAS codon 13 mutation is an independent predictor for colorectal cancer metachronous distant metastases.
Author:	Feng, Qingyang\|Liang, Li\|Ren, Li\|Chen, Jingwen\|Wei, Ye\|Chang, Wenju\|Zhu, Dexiang\|Lin, Qi\|Zheng, Peng\|Xu, Jianmin
PMID:	25973306

1960.
Journal:	Expert Rev Mol Diagn. 2015;15(8):979-87.
Title:	The distinctive molecular, pathological and clinical characteristics of BRAF-mutant colorectal tumors.
Author:	Scartozzi, Mario\|Giampieri, Riccardo\|Aprile, Giuseppe\|Iacono, Donatella\|Santini, Daniele\|dell'Aquila, Emanuela\|Silvestris, Nicola\|Gnoni, Antonio\|Bonotto, Marta\|Puzzoni, Marco\|Demurtas, Laura\|Cascinu, Stefano
PMID:	25975986

1961.
Journal:	Eur J Cancer. 2015 Jul;51(11):1405-14.
Title:	Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17.
Author:	Brule, S Y\|Jonker, D J\|Karapetis, C S\|O'Callaghan, C J\|Moore, M J\|Wong, R\|Tebbutt, N C\|Underhill, Cr\|Yip, D\|Zalcberg, J R\|Tu, D\|Goodwin, R A
PMID:	25979833

1962.
Journal:	Gastroenterol Res Pract. 2015;2015:753903.
Title:	KRAS and BRAF Mutation Detection: Is Immunohistochemistry a Possible Alternative to Molecular Biology in Colorectal Cancer?
Author:	Piton, Nicolas\|Borrini, Francesco\|Bolognese, Antonio\|Lamy, Aude\|Sabourin, Jean-Christophe
PMID:	25983749

1963.
Journal:	Oncotarget. 2015 May 20;6(14):12310-25.
Title:	Celecoxib increases EGF signaling in colon tumor associated fibroblasts, modulating EGFR expression and degradation.
Author:	Vene, Roberta\|Tosetti, Francesca\|Minghelli, Simona\|Poggi, Alessandro\|Ferrari, Nicoletta\|Benelli, Roberto
PMID:	25987127

1964.
Journal:	Int J Clin Oncol. 2015 Dec;20(6):1147-55.
Title:	Gene-expression profiles correlate with the efficacy of anti-EGFR therapy and chemotherapy for colorectal cancer.
Author:	Inoue, Masahiro\|Takahashi, Shin\|Soeda, Hiroshi\|Shimodaira, Hideki\|Watanabe, Mika\|Miura, Koh\|Sasaki, Iwao\|Kato, Shunsuke\|Ishioka, Chikashi
PMID:	25990448

1965.
Journal:	Am Soc Clin Oncol Educ Book. 2015:e149-56.
Title:	Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	25993166

1966.
Journal:	Am Soc Clin Oncol Educ Book. 2015:e197-206.
Title:	Biologic therapies in colorectal cancer: indications and contraindications.
Author:	Fakih, Marwan
PMID:	25993173

1967.
Journal:	J Control Release. 2015 Jul 28;210:26-38.
Title:	Cetuximab-oxaliplatin-liposomes for epidermal growth factor receptor targeted chemotherapy of colorectal cancer.
Author:	Zalba, Sara\|Contreras, Ana M\|Haeri, Azadeh\|Ten Hagen, Timo L M\|Navarro, Inigo\|Koning, Gerben\|Garrido, Maria J
PMID:	25998052

1968.
Journal:	Nat Cell Biol. 2015 Jun;17(6):804-15.
Title:	RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
Author:	Depeille, Philippe\|Henricks, Linda M\|van de Ven, Robert A H\|Lemmens, Ed\|Wang, Chih-Yang\|Matli, Mary\|Werb, Zena\|Haigis, Kevin M\|Donner, David\|Warren, Robert\|Roose, Jeroen P
PMID:	26005835

1969.
Journal:	Genomics. 2015 Aug;106(2):71-5.
Title:	Discrepancies between the K-ras mutational status of primary colorectal cancers and corresponding liver metastases are found in codon 13.
Author:	Kawamata, Hiroshi\|Yamashita, Keishi\|Kojo, Ken\|Ushiku, Hideki\|Ooki, Akira\|Watanabe, Masahiko
PMID:	26026309

1970.
Journal:	Drug Resist Updat. 2015 May;20:39-70.
Title:	Pharmacogenomics of intrinsic and acquired pharmacoresistance in colorectal cancer: Toward targeted personalized therapy.
Author:	De Mattia, Elena\|Cecchin, Erika\|Toffoli, Giuseppe
PMID:	26027741

1971.
Journal:	J Gastrointest Oncol. 2015 Jun;6(3):314-21.
Title:	Extended RAS testing in metastatic colorectal cancer-Refining the predictive molecular biomarkers.
Author:	Al-Shamsi, Humaid O\|Alhazzani, Waleed\|Wolff, Robert A
PMID:	26029459

1972.
Journal:	Nat Med. 2015 Jul;21(7):795-801.
Title:	Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Author:	Siravegna, Giulia\|Mussolin, Benedetta\|Buscarino, Michela\|Corti, Giorgio\|Cassingena, Andrea\|Crisafulli, Giovanni\|Ponzetti, Agostino\|Cremolini, Chiara\|Amatu, Alessio\|Lauricella, Calogero\|Lamba, Simona\|Hobor, Sebastijan\|Avallone, Antonio\|Valtorta, Emanuele\|R
PMID:	26030179

1973.
Journal:	Clin Cancer Res. 2015 Jun 1;21(11):2462-70.
Title:	Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors.
Author:	Juric, Dejan\|Dienstmann, Rodrigo\|Cervantes, Andres\|Hidalgo, Manuel\|Messersmith, Wells\|Blumenschein, George R Jr\|Tabernero, Josep\|Roda, Desamparados\|Calles, Antonio\|Jimeno, Antonio\|Wang, Xiaodong\|Bohorquez, Sandra Sanabria\|Leddy, Cecilia\|Littman, Catherine
PMID:	26034219

1974.
Journal:	Expert Rev Anticancer Ther. 2015 Jun;15(6):715-25.
Title:	Colorectal cancer: using blood samples and tumor tissue to detect K-ras mutations.
Author:	Li, Yang\|Fu, Xiao-Hong\|Yuan, Jin-Qiu\|Yang, Zu-Yao\|Mao, Chen\|Dong, Xiao-Mei\|Tang, Jin-Ling\|Wang, Sheng-Yong
PMID:	26035720

1975.
Journal:	Pathol Oncol Res. 2015 Sep;21(4):1201-8.
Title:	Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
Author:	Chen, Yi-Ting\|Tsao, Shu-Chuan\|Yuan, Shyng-Shiou F\|Tsai, Hung-Pei\|Chai, Chee-Yin
PMID:	26037168

1976.
Journal:	BMC Cancer. 2015 Jun 5;15:456.
Title:	Matrix metalloproteases as maestros for the dual role of LPS- and IL-10-stimulated macrophages in cancer cell behaviour.
Author:	Cardoso, Ana P\|Pinto, Marta L\|Pinto, Ana T\|Pinto, Marta T\|Monteiro, Catia\|Oliveira, Marta I\|Santos, Susana G\|Relvas, Joao B\|Seruca, Raquel\|Mantovani, Alberto\|Mareel, Marc\|Barbosa, Mario A\|Oliveira, Maria J
PMID:	26043921

1977.
Journal:	Expert Opin Investig Drugs. 2015;24(9):1185-98.
Title:	Role and mechanisms of resistance of epidermal growth factor receptor antagonists in the treatment of colorectal cancer.
Author:	Rihawi, Karim\|Giampieri, Riccardo\|Scartozzi, Mario\|Pusceddu, Valeria\|Bonotto, Marta\|Fasola, Gianpiero\|Cascinu, Stefano\|Aprile, Giuseppe
PMID:	26044119

1978.
Journal:	Int J Clin Exp Pathol. 2015 Mar 1;8(3):2888-98. eCollection 2015.
Title:	Biomarkers of erlotinib response in non-small cell lung cancer tumors that do not harbor the more common epidermal growth factor receptor mutations.
Author:	Lopez-Ayllon, Blanca D\|de Castro-Carpeno, Javier\|Rodriguez, Carlos\|Pernia, Olga\|Ibanez de Caceres, Inmaculada\|Belda-Iniesta, Cristobal\|Perona, Rosario\|Sastre, Leandro
PMID:	26045797

1979.
Journal:	Genes Chromosomes Cancer. 2015 Aug;54(8):506-515.
Title:	ADRM1-amplified metastasis gene in gastric cancer.
Author:	Fejzo, Marlena S\|Anderson, Lee\|Chen, Hsiao-Wang\|Anghel, Adrian\|Zhuo, Jiaying\|Anchoori, Ravi\|Roden, Richard\|Slamon, Dennis J
PMID:	26052681

1980.
Journal:	J Proteomics. 2015 Aug 3;126:54-67.
Title:	Quantitative proteomic analysis of paired colorectal cancer and non-tumorigenic tissues reveals signature proteins and perturbed pathways involved in CRC progression and metastasis.
Author:	Sethi, Manveen K\|Thaysen-Andersen, Morten\|Kim, Hoguen\|Park, Cheol Keun\|Baker, Mark S\|Packer, Nicolle H\|Paik, Young-Ki\|Hancock, William S\|Fanayan, Susan
PMID:	26054784

1981.
Journal:	Onco Targets Ther. 2015 May 26;8:1229-37.
Title:	Positive feedback between oncogenic KRAS and HIF-1alpha confers drug resistance in colorectal cancer.
Author:	Wang, Yanzhao\|Lei, Fuming\|Rong, Wanshui\|Zeng, Qingmin\|Sun, Wenbing
PMID:	26060408

1982.
Journal:	DNA Cell Biol. 2015 Aug;34(8):541-9.
Title:	The Tumor Suppressive Effects of HPP1 Are Mediated Through JAK-STAT-Interferon Signaling Pathways.
Author:	Hernandez, Jonathan M\|Elahi, Abul\|Clark, Whalen\|Humphries, Leigh Ann\|Wang, Jian\|Achille, Alex\|Seto, Ed\|Shibata, David
PMID:	26061044

1983.
Journal:	Biomed Res Int. 2015;2015:823620.
Title:	MicroRNAs as Regulator of Signaling Networks in Metastatic Colon Cancer.
Author:	Wang, Jian\|Du, Yong\|Liu, Xiaoming\|Cho, William C\|Yang, Yinxue
PMID:	26064956

1984.
Journal:	Expert Opin Biol Ther. 2015;15(8):1205-20.
Title:	The importance of optimal drug sequencing in metastatic colorectal cancer: biological rationales for the observed survival benefit conferred by first-line treatment with EGFR inhibitors.
Author:	Wainberg, Zev A\|Drakaki, Alexandra
PMID:	26066903

1985.
Journal:	Clin Cancer Res. 2015 Aug 1;21(15):3377-83.
Title:	Molecular Pathways: Sensitivity and Resistance to Anti-EGFR Antibodies.
Author:	Bertotti, Andrea\|Sassi, Francesco
PMID:	26071484

1986.
Journal:	World J Gastroenterol. 2015 Jun 7;21(21):6470-8.
Title:	Different treatment strategies and molecular features between right-sided and left-sided colon cancers.
Author:	Shen, Hong\|Yang, Jiao\|Huang, Qing\|Jiang, Meng-Jie\|Tan, Yi-Nuo\|Fu, Jian-Fei\|Zhu, Li-Zhen\|Fang, Xue-Feng\|Yuan, Ying
PMID:	26074686

1987.
Journal:	Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Sep;159(3):466-71.
Title:	Comparison of the prevalence of KRAS-LCS6 polymorphism (rs61764370) within different tumour types (colorectal, breast, non-small cell lung cancer and brain tumours). A study of the Czech population.
Author:	Uvirova, Magdalena\|Simova, Jarmila\|Kubova, Barbora\|Dvorackova, Nina\|Tomaskova, Hana\|Sedivcova, Monika\|Dite, Petr
PMID:	26077004

1988.
Journal:	Clin Colorectal Cancer. 2015 Dec;14(4):203-18.
Title:	Current and Future Approaches to Target the Epidermal Growth Factor Receptor and Its Downstream Signaling in Metastatic Colorectal Cancer.
Author:	Lee, Michael S\|Kopetz, Scott
PMID:	26077270

1989.
Journal:	BMC Cancer. 2015 Jun 16;15:471.
Title:	The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma.
Author:	Chen, Shuo\|Gou, Wen-Feng\|Zhao, Shuang\|Niu, Zhe-Feng\|Zhao, Yang\|Takano, Yasuo\|Zheng, Hua-Chuan
PMID:	26077911

1990.
Journal:	J Exp Clin Cancer Res. 2015 Jun 18;34:63.
Title:	The mutation rates of EGFR in non-small cell lung cancer and KRAS in colorectal cancer of Chinese patients as detected by pyrosequencing using a novel dispensation order.
Author:	Xie, Guohua\|Xie, Fang\|Wu, Ping\|Yuan, Xiangliang\|Ma, Yanhui\|Xu, Yunchuan\|Li, Li\|Xu, Ling\|Yang, Ming\|Shen, Lisong
PMID:	26081767

1991.
Journal:	Glycobiology. 2015 Oct;25(10):1064-78.
Title:	In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.
Author:	Sethi, Manveen K\|Kim, Hoguen\|Park, Cheol Keun\|Baker, Mark S\|Paik, Young-Ki\|Packer, Nicolle H\|Hancock, William S\|Fanayan, Susan\|Thaysen-Andersen, Morten
PMID:	26085185

1992.
Journal:	Autophagy. 2015;11(8):1373-88.
Title:	The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.
Author:	Wiersma, Valerie R\|de Bruyn, Marco\|Wei, Yunwei\|van Ginkel, Robert J\|Hirashima, Mitsuomi\|Niki, Toshiro\|Nishi, Nozomu\|Zhou, Jin\|Pouwels, Simon D\|Samplonius, Douwe F\|Nijman, Hans W\|Eggleton, Paul\|Helfrich, Wijnand\|Bremer, Edwin
PMID:	26086204

1993.
Journal:	Crit Rev Oncol Hematol. 2015 Oct;96(1):156-66.
Title:	First-line anti-EGFR monoclonal antibodies in panRAS wild-type metastatic colorectal cancer: A systematic review and meta-analysis.
Author:	Pietrantonio, Filippo\|Cremolini, Chiara\|Petrelli, Fausto\|Di Bartolomeo, Maria\|Loupakis, Fotios\|Maggi, Claudia\|Antoniotti, Carlotta\|de Braud, Filippo\|Falcone, Alfredo\|Iacovelli, Roberto
PMID:	26088456

1994.
Journal:	Radiother Oncol. 2015 Sep;116(3):510-6.
Title:	EGFR and beta1-integrin targeting differentially affect colorectal carcinoma cell radiosensitivity and invasion.
Author:	Poschau, Mandy\|Dickreuter, Ellen\|Singh-Muller, Jenny\|Zscheppang, Katja\|Eke, Iris\|Liersch, Torsten\|Cordes, Nils
PMID:	26096850

1995.
Journal:	EBioMedicine. 2015 May 1;2(5):447-455.
Title:	Aspirin Prevents Colorectal Cancer by Normalizing EGFR Expression.
Author:	Li, Haitao\|Zhu, Feng\|Boardman, Lisa A\|Wang, Lei\|Oi, Naomi\|Liu, Kangdong\|Li, Xiang\|Fu, Yang\|Limburg, Paul J\|Bode, Ann M\|Dong, Zigang
PMID:	26097892

1996.
Journal:	Expert Opin Ther Targets. 2015;19(8):1017-26.
Title:	MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1.
Author:	Mussnich, Paula\|Rosa, Roberta\|Bianco, Roberto\|Fusco, Alfredo\|D'Angelo, Daniela
PMID:	26107137

1997.
Journal:	PLoS One. 2015 Jun 24;10(6):e0131363.
Title:	Simultaneous inhibition of EGFR/VEGFR and cyclooxygenase-2 targets stemness-related pathways in colorectal cancer cells.
Author:	Valverde, Araceli\|Penarando, Jon\|Canas, Amanda\|Lopez-Sanchez, Laura M\|Conde, Francisco\|Hernandez, Vanessa\|Peralbo, Esther\|Lopez-Pedrera, Chary\|de la Haba-Rodriguez, Juan\|Aranda, Enrique\|Rodriguez-Ariza, Antonio
PMID:	26107817

1998.
Journal:	PLoS One. 2015 Jun 25;10(6):e0130543.
Title:	EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells.
Author:	Roda, Desamparados\|Castillo, Josefa\|Telechea-Fernandez, Marcelino\|Gil, Anabel\|Lopez-Rodas, Gerardo\|Franco, Luis\|Gonzalez-Rodriguez, Patricia\|Rosello, Susana\|Perez-Fidalgo, J Alejandro\|Garcia-Trevijano, Elena R\|Cervantes, Andres\|Zaragoza, Rosa
PMID:	26110767

1999.
Journal:	Cancer Chemother Pharmacol. 2015 Oct;76(4):659-77.
Title:	Current controversies in the management of metastatic colorectal cancer.
Author:	Vera, Ruth\|Alonso, Vicente\|Gallego, Javier\|Gonzalez, Encarnacion\|Guillen-Ponce, Carmen\|Pericay, Carles\|Rivera, Fernando\|Safont, M Jose\|Valladares-Ayerbes, Manuel
PMID:	26113053

2000.
Journal:	EBioMedicine. 2014 Nov 15;2(1):82-90.
Title:	A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer.
Author:	Krishna, Sanjeev\|Ganapathi, Senthil\|Ster, Irina Chis\|Saeed, Mohamed E M\|Cowan, Matt\|Finlayson, Caroline\|Kovacsevics, Hajnalka\|Jansen, Herwig\|Kremsner, Peter G\|Efferth, Thomas\|Kumar, Devinder
PMID:	26137537

2001.
Journal:	EBioMedicine. 2015 Feb 14;2(4):317-23.
Title:	Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study.
Author:	Yoshino, Takayuki\|Muro, Kei\|Yamaguchi, Kensei\|Nishina, Tomohiro\|Denda, Tadamichi\|Kudo, Toshihiro\|Okamoto, Wataru\|Taniguchi, Hiroya\|Akagi, Kiwamu\|Kajiwara, Takeshi\|Hironaka, Shuichi\|Satoh, Taroh
PMID:	26137573

2002.
Journal:	Cancer Treat Rev. 2015 Sep;41(8):671-9.
Title:	Rectal and colon cancer: Not just a different anatomic site.
Author:	Tamas, K\|Walenkamp, A M E\|de Vries, E G E\|van Vugt, M A T M\|Beets-Tan, R G\|van Etten, B\|de Groot, D J A\|Hospers, G A P
PMID:	26145760

2003.
Journal:	J Transl Med. 2015 Jul 7;13:217.
Title:	Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer.
Author:	Hutchinson, Ryan A\|Adams, Richard A\|McArt, Darragh G\|Salto-Tellez, Manuel\|Jasani, Bharat\|Hamilton, Peter W
PMID:	26149458

2004.
Journal:	Mol Med Rep. 2015 Oct;12(4):5407-14.
Title:	Combinational treatment with microRNA133b and cetuximab has increased inhibitory effects on the growth and invasion of colorectal cancer cells by regulating EGFR.
Author:	Zhou, Jianyu\|Lv, Lv\|Lin, Changwei\|Hu, Gui\|Guo, Yihang\|Wu, Meirong\|Tian, Buning\|Li, Xiaorong
PMID:	26151111

2005.
Journal:	Nat Med. 2015 Jul;21(7):827.
Title:	Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Author:	Siravegna, Giulia\|Mussolin, Benedetta\|Buscarino, Michela\|Corti, Giorgio\|Cassingena, Andrea\|Crisafulli, Giovanni\|Ponzetti, Agostino\|Cremolini, Chiara\|Amatu, Alessio\|Lauricella, Calogero\|Lamba, Simona\|Hobor, Sebastijan\|Avallone, Antonio\|Valtorta, Emanuele\|R
PMID:	26151329

2006.
Journal:	Int J Oncol. 2015 Sep;47(3):1034-42.
Title:	Cortactin promotes colon cancer progression by regulating ERK pathway.
Author:	Ni, Qing-Feng\|Yu, Jia-Wei\|Qian, Fei\|Sun, Nai-Zhi\|Xiao, Jian-Jia\|Zhu, Jian-Wei
PMID:	26151562

2007.
Journal:	Biochem Biophys Res Commun. 2015 Aug 21;464(2):519-25.
Title:	LRIG1, a 3p tumor suppressor, represses EGFR signaling and is a novel epigenetic silenced gene in colorectal cancer.
Author:	Kou, Changhua\|Zhou, Tian\|Han, Xilin\|Zhuang, Huijie\|Qian, Haixin
PMID:	26159916

2008.
Journal:	Crit Rev Oncol Hematol. 2015 Nov;96(2):355-71.
Title:	Risk of grade 3-4 diarrhea and mucositis in colorectal cancer patients receiving anti-EGFR monoclonal antibodies regimens: A meta-analysis of 18 randomized controlled clinical trials.
Author:	Miroddi, Marco\|Sterrantino, Carmelo\|Simonelli, Ilaria\|Ciminata, Giorgio\|Phillips, Robert S\|Calapai, Gioacchino
PMID:	26160607

2009.
Journal:	Folia Histochem Cytobiol. 2015;53(2):105-19.
Title:	The Hippo pathway in colorectal cancer.
Author:	Wierzbicki, Piotr M\|Rybarczyk, Agnieszka
PMID:	26160682

2010.
Journal:	Oncotarget. 2015 Jul 10;6(19):16902-11.
Title:	ErbB-3 activation by NRG-1beta sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs).
Author:	Prasetyanti, Pramudita R\|Capone, Emily\|Barcaroli, Daniela\|D'Agostino, Daniela\|Volpe, Silvia\|Benfante, Antonina\|van Hooff, Sander\|Iacobelli, Valentina\|Rossi, Cosmo\|Iacobelli, Stefano\|Medema, Jan Paul\|De Laurenzi, Vincenzo\|Sala, Gianluca
PMID:	26160848

2011.
Journal:	Curr Treat Options Oncol. 2015 Aug;16(8):41.
Title:	Cost Considerations in the Evaluation and Treatment of Colorectal Cancer.
Author:	Shankaran, Veena
PMID:	26162432

2012.
Journal:	Pathol Res Pract. 2015 Sep;211(9):665-70.
Title:	Morphological aspects of the hepatic response to neoadjuvant therapy.
Author:	Fernandez-Acenero, M J\|Cortes-Guiral, D\|Munoz, L Estrada\|Martinez-Useros, J\|Pastor-Idoate, C
PMID:	26163186

2013.
Journal:	Exp Mol Pathol. 2015 Oct;99(2):207-11.
Title:	Development of pyrosequencing methods for the rapid detection of RAS mutations in clinical samples.
Author:	Cortes, Ulrich\|Guilloteau, Karline\|Rouvreau, Melanie\|Archaimbault, Celine\|Villalva, Claire\|Karayan-Tapon, Lucie
PMID:	26163758

2014.
Journal:	Clin Transl Gastroenterol. 2015 Jul 16;6:e101.
Title:	EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging.
Author:	Zhou, Juan\|Joshi, Bishnu P\|Duan, Xiyu\|Pant, Asha\|Qiu, Zhen\|Kuick, Rork\|Owens, Scott R\|Wang, Thomas D
PMID:	26181290

2015.
Journal:	Contemp Oncol (Pozn). 2015;19(1):48-53.
Title:	The prognostic significance of tumor epidermal growth factor receptor (EGFR) expression change after neoadjuvant chemoradiation in patients with rectal adenocarcinoma.
Author:	Richter, Igor\|Dvorak, Josef\|Urbanec, Marek\|Bluml, Antonin\|Cermakova, Eva\|Bartos, Jiri\|Petera, Jiri
PMID:	26199571

2016.
Journal:	Br J Surg. 2015 Sep;102(10):1175-83.
Title:	Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases.
Author:	Brudvik, K W\|Kopetz, S E\|Li, L\|Conrad, C\|Aloia, T A\|Vauthey, J-N
PMID:	26206254

2017.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2374-81.
Title:	Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer.
Author:	Stintzing, Sebastian\|Zhang, Wu\|Heinemann, Volker\|Neureiter, Daniel\|Kemmerling, Ralf\|Kirchner, Thomas\|Jung, Andreas\|Folwaczny, Matthias\|Yang, Dongyun\|Ning, Yan\|Sebio, Ana\|Stremitzer, Stefan\|Sunakawa, Yu\|Matsusaka, Satoshi\|Yamauchi, Shinichi\|Loupakis, Fotio
PMID:	26206335

2018.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2187-97.
Title:	BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Author:	Tang, Zhiyu\|Yuan, Xi\|Du, Rong\|Cheung, Shing-Hu\|Zhang, Guoliang\|Wei, Jing\|Zhao, Yuan\|Feng, Yingcai\|Peng, Hao\|Zhang, Yi\|Du, Yunguang\|Hu, Xiaoxia\|Gong, Wenfeng\|Liu, Yong\|Gao, Yajuan\|Liu, Ye\|Hao, Rui\|Li, Shengjian\|Wang, Shaohui\|Ji, Jiafu\|Zhang, Lianhai\|Li, Sh
PMID:	26208524

2019.
Journal:	J BUON. 2015 May-Jun;20(3):680-9.
Title:	HIF-1alpha in colorectal carcinoma: review of the literature.
Author:	Ioannou, Maria\|Paraskeva, Efrosyni\|Baxevanidou, Korina\|Simos, George\|Papamichali, Roidoula\|Papacharalambous, Constantina\|Samara, Maria\|Koukoulis, George
PMID:	26214618

2020.
Journal:	Diagn Pathol. 2015 Jul 30;10:132.
Title:	Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique.
Author:	Kriegsmann, Mark\|Arens, Norbert\|Endris, Volker\|Weichert, Wilko\|Kriegsmann, Jorg
PMID:	26220423

2021.
Journal:	Mod Pathol. 2015 Oct;28(10):1390-9.
Title:	Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers.
Author:	Haley, Lisa\|Tseng, Li-Hui\|Zheng, Gang\|Dudley, Jonathan\|Anderson, Derek A\|Azad, Nilofer S\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26226847

2022.
Journal:	Cancer Genet. 2015 Sep;208(9):441-7.
Title:	Diagnostic yield of targeted next generation sequencing in various cancer types: an information-theoretic approach.
Author:	Hagemann, Ian S\|O'Neill, Patrick K\|Erill, Ivan\|Pfeifer, John D
PMID:	26227479

2023.
Journal:	Nanomedicine. 2015 Nov;11(8):1883-92.
Title:	Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells.
Author:	Gener, Petra\|Gouveia, Luis Pleno\|Sabat, Guillem Romero\|de Sousa Rafael, Diana Fernandes\|Fort, Nuria Bergada\|Arranja, Alexandra\|Fernandez, Yolanda\|Prieto, Rafael Minana\|Ortega, Joan Sayos\|Arango, Diego\|Abasolo, Ibane\|Videira, Mafalda\|Schwartz, Simo Jr
PMID:	26238079

2024.
Journal:	Nanoscale. 2015 Sep 7;7(33):14080-92.
Title:	Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles.
Author:	Chen, Lijue\|She, Xiaodong\|Wang, Tao\|He, Li\|Shigdar, Sarah\|Duan, Wei\|Kong, Lingxue
PMID:	26242620

2025.
Journal:	Cancer Discov. 2015 Aug;5(8):799-801.
Title:	ERBB2 emerges as a new target for colorectal cancer.
Author:	Pectasides, Eirini\|Bass, Adam J
PMID:	26243861

2026.
Journal:	Cancer Discov. 2015 Aug;5(8):832-41.
Title:	HER2 activating mutations are targets for colorectal cancer treatment.
Author:	Kavuri, Shyam M\|Jain, Naveen\|Galimi, Francesco\|Cottino, Francesca\|Leto, Simonetta M\|Migliardi, Giorgia\|Searleman, Adam C\|Shen, Wei\|Monsey, John\|Trusolino, Livio\|Jacobs, Samuel A\|Bertotti, Andrea\|Bose, Ron
PMID:	26243863

2027.
Journal:	Oncoscience. 2015 Jul 1;2(6):581-4.
Title:	Durable clinical benefit to trastuzumab and chemotherapy in a patient with metastatic colon adenocarcinoma harboring ERBB2 amplification.
Author:	Disel, Umut\|Germain, Alexis\|Yilmazel, Bahar\|Abali, Huseyin\|Bolat, Filiz Aka\|Yelensky, Roman\|Elvin, Julia A\|Lipson, Doron\|Chmielecki, Juliann\|Wang, Kai\|Stephens, Philip J\|Ross, Jeffrey S\|Miller, Vincent A\|Ali, Siraj M\|George, Thomas J Jr
PMID:	26244165

2028.
Journal:	Pol J Pathol. 2015 Jun;66(2):109-20.
Title:	Can the histological type of colorectal cancer determine the carcinogenesis pathway?
Author:	Kolos, Malgorzata\|Wasaznik-Jedras, Anna\|Nasierowska-Guttmejer, Anna
PMID:	26247523

2029.
Journal:	PLoS One. 2015 Aug 10;10(8):e0134948.
Title:	Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array.
Author:	Chung, Seyung\|Dwabe, Sami\|Elshimali, Yayha\|Sukhija, Hemlata\|Aroh, Clement\|Vadgama, Jaydutt V
PMID:	26258407

2030.
Journal:	Oncogenesis. 2015 Aug 10;4:e162.
Title:	SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression.
Author:	Tiwari, R\|Pandey, S K\|Goel, S\|Bhatia, V\|Shukla, S\|Jing, X\|Dhanasekaran, S M\|Ateeq, B
PMID:	26258891

2031.
Journal:	Appl Immunohistochem Mol Morphol. 2015 Aug;23(7):506-15.
Title:	Mucinous Colorectal Adenocarcinoma: Influence of EGFR and E-Cadherin Expression on Clinicopathologic Features and Prognosis.
Author:	Foda, Abd AlRahman M\|AbdelAziz, Azza\|El-Hawary, Amira K\|Hosni, Ali\|Zalata, Khalid R\|Gado, Asmaa I
PMID:	26262813

2032.
Journal:	Cancer Cell. 2015 Aug 10;28(2):183-97.
Title:	ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development.
Author:	Fang, Lekun\|Lu, Weisi\|Choi, Hyun Ho\|Yeung, Sai-Ching J\|Tung, Jung-Yu\|Hsiao, Chwan-Deng\|Fuentes-Mattei, Enrique\|Menter, David\|Chen, Chuangqi\|Wang, Lei\|Wang, Jianping\|Lee, Mong-Hong
PMID:	26267535

2033.
Journal:	Am J Cancer Res. 2015 May 15;5(6):1972-87. eCollection 2015.
Title:	YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells.
Author:	Dubois, Fanny\|Leroy, Cedric\|Simon, Valerie\|Benistant, Christine\|Roche, Serge
PMID:	26269757

2034.
Journal:	Clin Cancer Res. 2015 Aug 15;21(16):3578-80.
Title:	CCR 20th Anniversary Commentary: RAS as a Biomarker for EGFR--Targeted Therapy for Colorectal Cancer-From Concept to Practice.
Author:	Camp, E Ramsay\|Ellis, Lee M
PMID:	26275951

2035.
Journal:	Z Gastroenterol. 2015 Aug;53(8):782-8.
Title:	[Clinically relevant, gender-specific differences in colorectal carcinoma (CRC)].
Author:	Hoffken, N\|Leichsenring, J\|Reinacher-Schick, A
PMID:	26284326

2036.
Journal:	Mol Cancer Res. 2015 Dec;13(12):1554-66.
Title:	Sulfiredoxin Promotes Colorectal Cancer Cell Invasion and Metastasis through a Novel Mechanism of Enhancing EGFR Signaling.
Author:	Jiang, Hong\|Wu, Lisha\|Chen, Jing\|Mishra, Murli\|Chawsheen, Hedy A\|Zhu, Haining\|Wei, Qiou
PMID:	26290602

2037.
Journal:	Rev Prat. 2015 Jun;65(6):802-6.
Title:	[Colorectal cancer biology].
Author:	Perkins, Geraldine\|Laurent-Puig, Pierre
PMID:	26298904

2038.
Journal:	Mol Biol (Mosk). 2015 Jul-Aug;49(4):617-27.
Title:	[Biochip detection of KRAS, BRAF, and PIK3CA somatic mutations in colorectal cancer patients].
Author:	Emelyanova, M A\|Amossenko, F A\|Semyanikhina, A V\|Aliev, V A\|Barsukov, Yu A\|Lyubchenko, L N\|Nasedkina, T V
PMID:	26299862

2039.
Journal:	Nat Commun. 2015 Aug 24;6:8022.
Title:	Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway.
Author:	Song, Wei\|Liu, Wenjie\|Zhao, Hong\|Li, Shangze\|Guan, Xin\|Ying, Jianming\|Zhang, Yefan\|Miao, Fei\|Zhang, Mengmeng\|Ren, Xiaoxia\|Li, Xiaolu\|Wu, Fan\|Zhao, Yuechao\|Tian, Yuanyuan\|Wu, Wenming\|Fu, Jun\|Liang, Junbo\|Wu, Wei\|Liu, Changzheng\|Yu, Jia\|Zong, Shudong\|Miao,
PMID:	26300397

2040.
Journal:	Oncotarget. 2015 Oct 6;6(30):30384-93.
Title:	89Zr-cetuximab PET imaging in patients with advanced colorectal cancer.
Author:	Menke-van der Houven van Oordt, Catharina Willemien\|Gootjes, Elske C\|Huisman, Marc C\|Vugts, Danielle J\|Roth, Chantal\|Luik, Anne Marije\|Mulder, Emma R\|Schuit, Robert C\|Boellaard, Ronald\|Hoekstra, Otto S\|van Dongen, Guus Ams\|Verheul, Henk M W
PMID:	26309164

2041.
Journal:	Virchows Arch. 2015 Oct;467(4):383-92.
Title:	KRAS mutations in microsatellite instable gastric tumours: impact of targeted treatment and intratumoural heterogeneity.
Author:	Queiros, Pedro\|Pinheiro, Hugo\|Carvalho, Joana\|Oliveira, Patricia\|Gullo, Irene\|Carneiro, Fatima\|Almeida, Gabriela M\|Oliveira, Carla
PMID:	26318594

2042.
Journal:	Bioorg Med Chem Lett. 2015 Oct 1;25(19):4287-92.
Title:	Probing a 3,4'-bis-guanidinium diaryl derivative as an allosteric inhibitor of the Ras pathway.
Author:	Diez-Cecilia, Elena\|Carson, Robert\|Kelly, Brendan\|van Schaeybroeck, Sandra\|Murray, James T\|Rozas, Isabel
PMID:	26318998

2043.
Journal:	Oncol Rep. 2015 Nov;34(5):2768-75.
Title:	Isolation and characterization of circulating micro(nano)vesicles in the plasma of colorectal cancer patients and their interactions with tumor cells.
Author:	Stec, Malgorzata\|Baj-Krzyworzeka, Monika\|Baran, Jaroslaw\|Weglarczyk, Kazimierz\|Zembala, Maria\|Barbasz, Jakub\|Szczepanik, Antoni\|Zembala, Marek
PMID:	26324403

2044.
Journal:	Ther Adv Med Oncol. 2015 Sep;7(5):252-62.
Title:	Precision medicine in colorectal cancer: the molecular profile alters treatment strategies.
Author:	Tran, Nguyen H\|Cavalcante, Ludmila L\|Lubner, Sam J\|Mulkerin, Daniel L\|LoConte, Noelle K\|Clipson, Linda\|Matkowskyj, Kristina A\|Deming, Dustin A
PMID:	26327923

2045.
Journal:	Am J Cancer Res. 2015 Jun 15;5(7):2277-84. eCollection 2015.
Title:	Correlation study of Bcl-2, B7-H1, EGFR, VEGF and colorectal cancer.
Author:	Li, Xiao-Feng\|Liu, Xian-Feng\|Yang, Yong-Yan\|Liu, Ai-Yong\|Zhang, Mei-Yun\|Bai, Xue-Feng\|Gao, Hui\|Guo, Xiao-Guang
PMID:	26328258

2046.
Journal:	J Transl Med. 2015 Sep 3;13:287.
Title:	The Italian external quality assessment for RAS testing in colorectal carcinoma identifies methods-related inter-laboratory differences.
Author:	Normanno, Nicola\|Pinto, Carmine\|Castiglione, Francesca\|Fenizia, Francesca\|Barberis, Massimo\|Marchetti, Antonio\|Fontanini, Gabriella\|De Rosa, Gaetano\|Taddei, Gian Luigi
PMID:	26335936

2047.
Journal:	J Nephrol. 2015 Dec;28(6):647-57.
Title:	Renal toxicity of anticancer agents targeting HER2 and EGFR.
Author:	Cosmai, Laura\|Gallieni, Maurizio\|Porta, Camillo
PMID:	26341657

2048.
Journal:	Oncogenesis. 2015 Sep 7;4:e165.
Title:	Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression.
Author:	Nukuda, A\|Sasaki, C\|Ishihara, S\|Mizutani, T\|Nakamura, K\|Ayabe, T\|Kawabata, K\|Haga, H
PMID:	26344692

2049.
Journal:	Drugs. 2015 Oct;75(15):1739-56.
Title:	Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2.
Author:	Boeckx, Nele\|Peeters, Marc\|Van Camp, Guy\|Pauwels, Patrick\|Op de Beeck, Ken\|Deschoolmeester, Vanessa
PMID:	26347132

2050.
Journal:	Cancer Gene Ther. 2015 Sep;22(9):417-30.
Title:	A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.
Author:	Dietel, M\|Johrens, K\|Laffert, M V\|Hummel, M\|Blaker, H\|Pfitzner, B M\|Lehmann, A\|Denkert, C\|Darb-Esfahani, S\|Lenze, D\|Heppner, F L\|Koch, A\|Sers, C\|Klauschen, F\|Anagnostopoulos, I
PMID:	26358176

2051.
Journal:	Cell Rep. 2015 Sep 29;12(12):1978-85.
Title:	PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.
Author:	Prahallad, Anirudh\|Heynen, Guus J J E\|Germano, Giovanni\|Willems, Stefan M\|Evers, Bastiaan\|Vecchione, Loredana\|Gambino, Valentina\|Lieftink, Cor\|Beijersbergen, Roderick L\|Di Nicolantonio, Federica\|Bardelli, Alberto\|Bernards, Rene
PMID:	26365186

2052.
Journal:	PLoS One. 2015 Sep 14;10(9):e0138245.
Title:	Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers.
Author:	D'Haene, Nicky\|Le Mercier, Marie\|De Neve, Nancy\|Blanchard, Oriane\|Delaunoy, Melanie\|El Housni, Hakim\|Dessars, Barbara\|Heimann, Pierre\|Remmelink, Myriam\|Demetter, Pieter\|Tejpar, Sabine\|Salmon, Isabelle
PMID:	26366557

2053.
Journal:	Curr Pharm Des. 2015;21(35):5116-26.
Title:	New Insights into the Mechanism of Action of Aspirin in the Prevention of Colorectal Neoplasia.
Author:	Di Francesco, Luigia\|Lopez Contreras, Luilli Antonio\|Sacco, Angela\|Patrignani, Paola
PMID:	26369679

2054.
Journal:	Br J Cancer. 2015 Sep 29;113(7):1010-9.
Title:	Acquired resistance to anti-EGFR mAb ICR62 in cancer cells is accompanied by an increased EGFR expression, HER-2/HER-3 signalling and sensitivity to pan HER blockers.
Author:	Khelwatty, Said A\|Essapen, Sharadah\|Seddon, Alan M\|Fan, Zhen\|Modjtahedi, Helmout
PMID:	26372697

2055.
Journal:	Curr Treat Options Oncol. 2015 Nov;16(11):52.
Title:	First-Line Treatment of Metastatic Colorectal Cancer: Interpreting FIRE-3, PEAK, and CALGB/SWOG 80405.
Author:	Elez, Elena\|Argiles, Guillem\|Tabernero, Josep
PMID:	26374340

2056.
Journal:	Drugs. 2015 Nov;75(16):1833-42.
Title:	Maintenance therapy for colorectal cancer: which regimen and which patients?
Author:	Mikhail, Sameh\|Bekaii-Saab, Tanios
PMID:	26377935

2057.
Journal:	Invest New Drugs. 2015 Dec;33(6):1242-7.
Title:	Safety and efficacy of the addition of simvastatin to cetuximab in previously treated KRAS mutant metastatic colorectal cancer patients.
Author:	Baas, J M\|Krens, L L\|ten Tije, A J\|Erdkamp, F\|van Wezel, T\|Morreau, H\|Gelderblom, H\|Guchelaar, H J
PMID:	26386973

2058.
Journal:	Nat Commun. 2015 Sep 22;6:8305.
Title:	Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers.
Author:	Misale, Sandra\|Bozic, Ivana\|Tong, Jingshan\|Peraza-Penton, Ashley\|Lallo, Alice\|Baldi, Federica\|Lin, Kevin H\|Truini, Mauro\|Trusolino, Livio\|Bertotti, Andrea\|Di Nicolantonio, Federica\|Nowak, Martin A\|Zhang, Lin\|Wood, Kris C\|Bardelli, Alberto
PMID:	26392303

2059.
Journal:	Anal Chem. 2015 Oct 20;87(20):10323-9.
Title:	Harvesting (67)Cu from the Collection of a Secondary Beam Cocktail at the National Superconducting Cyclotron Laboratory.
Author:	Mastren, Tara\|Pen, Aranh\|Loveless, Shaun\|Marquez, Bernadette V\|Bollinger, Elizabeth\|Marois, Boone\|Hubley, Nicholas\|Brown, Kyle\|Morrissey, David J\|Peaslee, Graham F\|Lapi, Suzanne E
PMID:	26403524

2060.
Journal:	Nature. 2015 Oct 8;526(7572):263-7.
Title:	The genomic landscape of response to EGFR blockade in colorectal cancer.
Author:	Bertotti, Andrea\|Papp, Eniko\|Jones, Sian\|Adleff, Vilmos\|Anagnostou, Valsamo\|Lupo, Barbara\|Sausen, Mark\|Phallen, Jillian\|Hruban, Carolyn A\|Tokheim, Collin\|Niknafs, Noushin\|Nesselbush, Monica\|Lytle, Karli\|Sassi, Francesco\|Cottino, Francesca\|Migliardi, Giorg
PMID:	26416732

2061.
Journal:	Oncotarget. 2015 Oct 13;6(31):31272-83.
Title:	Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors.
Author:	Serrano-Heras, Gemma\|Cuenca-Lopez, Maria Dolores\|Montero, Juan Carlos\|Corrales-Sanchez, Veronica\|Morales, Jorge Carlos\|Nunez, Luz-Elena\|Moris, Francisco\|Pandiella, Atanasio\|Ocana, Alberto
PMID:	26418718

2062.
Journal:	Cancer Sci. 2015 Dec;106(12):1722-9.
Title:	DNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer.
Author:	Ouchi, Kota\|Takahashi, Shin\|Yamada, Yasuhide\|Tsuji, Shingo\|Tatsuno, Kenji\|Takahashi, Hidekazu\|Takahashi, Naoki\|Takahashi, Masanobu\|Shimodaira, Hideki\|Aburatani, Hiroyuki\|Ishioka, Chikashi
PMID:	26426205

2063.
Journal:	J Exp Clin Cancer Res. 2015 Oct 1;34:108.
Title:	Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer.
Author:	Giordano, Guido\|Febbraro, Antonio\|Tomaselli, Eugenio\|Sarnicola, Maria Lucia\|Parcesepe, Pietro\|Parente, Domenico\|Forte, Nicola\|Fabozzi, Alessio\|Remo, Andrea\|Bonetti, Andrea\|Manfrin, Erminia\|Ghasemi, Somayehsadat\|Ceccarelli, Michele\|Cerulo, Luigi\|Bazzoni, F
PMID:	26427914

2064.
Journal:	Oncotarget. 2015 Oct 13;6(31):30592-603.
Title:	Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics.
Author:	Magliacane, Gilda\|Grassini, Greta\|Bartocci, Paola\|Francaviglia, Ilaria\|Dal Cin, Elena\|Barbieri, Gianluca\|Arrigoni, Gianluigi\|Pecciarini, Lorenza\|Doglioni, Claudio\|Cangi, Maria Giulia
PMID:	26435479

2065.
Journal:	Med Sci Monit. 2015 Oct 12;21:3068-76.
Title:	MTHFR C677T Polymorphism is Associated with Tumor Response to Preoperative Chemoradiotherapy: A Result Based on Previous Reports.
Author:	Zhao, Yue\|Li, Xingde\|Kong, Xiangjun
PMID:	26456456

2066.
Journal:	J Clin Oncol. 2015 Dec 1;33(34):4032-8.
Title:	Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.
Author:	Kopetz, Scott\|Desai, Jayesh\|Chan, Emily\|Hecht, Joel Randolph\|O'Dwyer, Peter J\|Maru, Dipen\|Morris, Van\|Janku, Filip\|Dasari, Arvind\|Chung, Woonbook\|Issa, Jean-Pierre J\|Gibbs, Peter\|James, Brian\|Powis, Garth\|Nolop, Keith B\|Bhattacharya, Suman\|Saltz, Leonard
PMID:	26460303

2067.
Journal:	Zhonghua Zhong Liu Za Zhi. 2015 May;37(5):342-6.
Title:	[Effect and mechanism of EGFR expression in macrophages on the anti-cancer effect of berberine on colorectal cancer].
Author:	Lu, Ning\|Tong, Zhongsheng\|Zhang, Mei\|Lu, Lu\|Cao, Hailong
PMID:	26463023

2068.
Journal:	Clin Cancer Res. 2015 Dec 15;21(24):5415-6.
Title:	Optimizing Anti-EGFR Therapy in Colorectal Cancer.
Author:	Salazar, Ramon\|Ciardiello, Fortunato
PMID:	26463710

2069.
Journal:	World J Clin Oncol. 2015 Oct 10;6(5):133-41.
Title:	Colon cancer and the epidermal growth factor receptor: Current treatment paradigms, the importance of diet, and the role of chemoprevention.
Author:	Pabla, Baldeep\|Bissonnette, Marc\|Konda, Vani J
PMID:	26468449

2070.
Journal:	Biopreserv Biobank. 2015 Oct;13(5):325-34.
Title:	Surgical Specimens of Colorectal Cancer Fixed with PAXgene Tissue System Preserve High-Quality RNA.
Author:	Hara, Keisuke\|Watanabe, Atsushi\|Matsumoto, Satoshi\|Matsuda, Yoko\|Kuwata, Takeshi\|Kan, Hayato\|Yamada, Takeshi\|Koizumi, Michihiro\|Shinji, Seiichi\|Yamagishi, Aya\|Ishiwata, Toshiyuki\|Naito, Zenya\|Shimada, Takashi\|Uchida, Eiji
PMID:	26484572

2071.
Journal:	Biomed Res Int. 2015;2015:397563.
Title:	Synergistic Inhibitory Effects of Cetuximab and Cisplatin on Human Colon Cancer Cell Growth via Inhibition of the ERK-Dependent EGF Receptor Signaling Pathway.
Author:	Son, Dong Ju\|Hong, Ji Eun\|Ban, Jung Ok\|Park, Ju Ho\|Lee, Hye Lim\|Gu, Sun Mi\|Hwang, Jae Yeon\|Jung, Myung Hee\|Lee, Dong Won\|Han, Sang-Bae\|Hong, Jin Tae
PMID:	26491668

2072.
Journal:	Nature. 2015 Oct 29;526(7575):715-8.
Title:	Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.
Author:	Gregorieff, Alex\|Liu, Yu\|Inanlou, Mohammad R\|Khomchuk, Yuliya\|Wrana, Jeffrey L
PMID:	26503053

2073.
Journal:	Anticancer Res. 2015 Nov;35(11):6175-81.
Title:	Prophylactic Effect of Oral Minocycline in Combination with Topical Steroid and Skin Care Against Panitumumab-induced Acneiform Rash in Metastatic Colorectal Cancer Patients.
Author:	Yamada, Maya\|Iihara, Hirotoshi\|Fujii, Hironori\|Ishihara, Masashi\|Matsuhashi, Nobuhisa\|Takahashi, Takao\|Yoshida, Kazuhiro\|Itoh, Yoshinori
PMID:	26504047

2074.
Journal:	BMC Cancer. 2015 Oct 27;15:808.
Title:	Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.
Author:	Lupini, Laura\|Bassi, Cristian\|Mlcochova, Jitka\|Musa, Gentian\|Russo, Marta\|Vychytilova-Faltejskova, Petra\|Svoboda, Marek\|Sabbioni, Silvia\|Nemecek, Radim\|Slaby, Ondrej\|Negrini, Massimo
PMID:	26508446

2075.
Journal:	Onco Targets Ther. 2015 Oct 15;8:2949-57.
Title:	Molecular profiling in the treatment of colorectal cancer: focus on regorafenib.
Author:	Yan, Yiyi\|Grothey, Axel
PMID:	26508880

2076.
Journal:	Oncotarget. 2015 Dec 1;6(38):40815-21.
Title:	A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations.
Author:	Chen, Dawei\|Huang, Xuesong\|Cai, Jie\|Guo, Sheng\|Qian, Wubin\|Wery, Jean-Pierre\|Li, Qi-Xiang
PMID:	26512781

2077.
Journal:	Oncotarget. 2015 Nov 10;6(35):38166-80.
Title:	Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways.
Author:	Greening, David W\|Lee, Sze Ting\|Ji, Hong\|Simpson, Richard J\|Rigopoulos, Angela\|Murone, Carmel\|Fang, Catherine\|Gong, Sylvia\|O'Keefe, Graeme\|Scott, Andrew M
PMID:	26517691

2078.
Journal:	Sci Rep. 2015 Nov 6;5:16082.
Title:	Nuclear PKM2 contributes to gefitinib resistance via upregulation of STAT3 activation in colorectal cancer.
Author:	Li, Qiong\|Zhang, Daoxiang\|Chen, Xiaoying\|He, Lei\|Li, Tianming\|Xu, Xiaoping\|Li, Min
PMID:	26542452

2079.
Journal:	Cancer Biol Ther. 2015;16(12):1726-37.
Title:	Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites.
Author:	El-Deiry, Wafik S\|Vijayvergia, Namrata\|Xiu, Joanne\|Scicchitano, Angelique\|Lim, Bora\|Yee, Nelson S\|Harvey, Harold A\|Gatalica, Zoran\|Reddy, Sandeep
PMID:	26553611

2080.
Journal:	J Biomed Nanotechnol. 2015 Nov;11(11):2034-49.
Title:	Cellular Uptake and Cytotoxic Effect of Epidermal Growth Factor Receptor Targeted and Plitidepsin Loaded Co-Polymeric Polymersomes on Colorectal Cancer Cell Lines.
Author:	Goni-de-Cerio, Felipe\|Thevenot, Julie\|Oliveira, Hugo\|Perez-Andres, Encarnacion\|Berra, Edurne\|Masa, Marc\|Suarez-Merino, Blanca\|Lecommandoux, Sebastien\|Heredia, Pedro
PMID:	26554161

2081.
Journal:	Contemp Oncol (Pozn). 2015;19(4):261-4.
Title:	The role of Reg IV in colorectal cancer, as a potential therapeutic target.
Author:	Hu, Yiwang\|Pan, Chi\|Hu, Jiyi\|Zhang, Suzhan
PMID:	26557771

2082.
Journal:	Int J Mol Sci. 2015 Nov 11;16(11):26936-52.
Title:	Exploring Different Strategies for Efficient Delivery of Colorectal Cancer Therapy.
Author:	Lin, Congcong\|Ng, Huei Leng Helena\|Pan, Weisan\|Chen, Hubiao\|Zhang, Ge\|Bian, Zhaoxiang\|Lu, Aiping\|Yang, Zhijun
PMID:	26569228

2083.
Journal:	PLoS One. 2015 Nov 16;10(11):e0143132.
Title:	Combined Analysis of Plasma Amphiregulin and Heregulin Predicts Response to Cetuximab in Metastatic Colorectal Cancer.
Author:	Yonesaka, Kimio\|Takegawa, Naoki\|Satoh, Taroh\|Ueda, Hiroto\|Yoshida, Takeshi\|Takeda, Masayuki\|Shimizu, Toshio\|Chiba, Yasutaka\|Okamoto, Isamu\|Nishio, Kazuto\|Tamura, Takao\|Nakagawa, Kazuhiko
PMID:	26569500

2084.
Journal:	J Clin Invest. 2015 Dec;125(12):4320-2.
Title:	Old dog, new tricks: extracellular domain arginine methylation regulates EGFR function.
Author:	Epstein, David M\|Buck, Elizabeth
PMID:	26571394

2085.
Journal:	J Clin Invest. 2015 Dec;125(12):4529-43.
Title:	PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response.
Author:	Liao, Hsin-Wei\|Hsu, Jung-Mao\|Xia, Weiya\|Wang, Hung-Ling\|Wang, Ying-Nai\|Chang, Wei-Chao\|Arold, Stefan T\|Chou, Chao-Kai\|Tsou, Pei-Hsiang\|Yamaguchi, Hirohito\|Fang, Yueh-Fu\|Lee, Hong-Jen\|Lee, Heng-Huan\|Tai, Shyh-Kuan\|Yang, Mhu-Hwa\|Morelli, Maria P\|Sen, Malabi
PMID:	26571401

2086.
Journal:	Expert Opin Drug Metab Toxicol. 2015;11(12):1907-24.
Title:	Pharmacokinetic and pharmacodynamic evaluation of panitumumab in the treatment of colorectal cancer.
Author:	Lo, Louisa\|Patel, Dainik\|Townsend, Amanda R\|Price, Timothy J
PMID:	26572750

2087.
Journal:	Biomed Res Int. 2015;2015:690721.
Title:	Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines.
Author:	Korpetinou, Angeliki\|Papachristou, Dionysios J\|Lampropoulou, Angeliki\|Bouris, Panagiotis\|Labropoulou, Vassiliki T\|Noulas, Argyrios\|Karamanos, Nikos K\|Theocharis, Achilleas D
PMID:	26581653

2088.
Journal:	Onco Targets Ther. 2015 Nov 2;8:3185-92.
Title:	Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma.
Author:	Cheng, Lei\|Xia, Zuguang\|Bian, Xinyu\|Li, Guangchao\|Hu, Jing\|Cao, Ya\|Wang, Qing\|Qian, Xiaoping
PMID:	26586952

2089.
Journal:	Rev Med Brux. 2015 Sep;36(4):263-6.
Title:	[Colorectal cancer: ten years of illusion of progress but advances are on the horizon].
Author:	Shaza, L\|Charette, N\|Hendlisz, A
PMID:	26591311

2090.
Journal:	Rinsho Byori. 2015 Jul;63(7):870-5.
Title:	[Companion Diagnostics Sub-Section of Anatomic Pathology Department in a Mid-Sized General Hospital: Start Up and Maintenance].
Author:	Nakayama, Hirofumi\|Yasuhara, Mayumi
PMID:	26591440

2091.
Journal:	Semin Oncol. 2015 Dec;42(6):896-908.
Title:	Overcoming Resistance to Targeted Therapies in Cancer.
Author:	Redmond, Keara L\|Papafili, Anastasia\|Lawler, Mark\|Van Schaeybroeck, Sandra
PMID:	26615134

2092.
Journal:	Pharmacogenomics. 2015 Dec;16(18):2069-81.
Title:	BRAF in metastatic colorectal cancer: the future starts now.
Author:	Orlandi, Armando\|Calegari, Alessandra\|Inno, Alessandro\|Berenato, Rosa\|Caporale, Marta\|Niger, Monica\|Bossi, Ilaria\|Di Bartolomeo, Maria\|de Braud, Filippo\|Pietrantonio, Filippo
PMID:	26615988

2093.
Journal:	Mol Clin Oncol. 2015 Sep;3(5):1053-1057.
Title:	Cetuximab treatment for metastatic colorectal cancer with KRAS p.G13D mutations improves progression-free survival.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Osako, Masahiko\|Kawazoe, Yoshimasa\|Oba, Masaru\|Misaka, Takaharu\|Goto, Takashi\|Kamo, Hitomi\|Suenaga, Mitsukuni\|Kumekawa, Yosuke\|Ogura, Mariko\|Ozaka, Masato\|Matsusaka, Satoshi\|Chin, Keisho\|Hatake, Kiyohiko\|Mizunuma, Nobuyuki
PMID:	26623049

2094.
Journal:	Horiz Cancer Res. 2015 2nd Quarter;56:23-40.
Title:	Targeting Cathepsin B for Cancer Therapies.
Author:	Ruan, Hang\|Hao, Susan\|Young, Peter\|Zhang, Hongtao
PMID:	26623174

2095.
Journal:	BMC Cancer. 2015 Dec 16;15:974.
Title:	Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors.
Author:	Li, Xi\|Pathi, Satya S\|Safe, Stephen
PMID:	26673922

2096.
Journal:	Ther Adv Med Oncol. 2015 May;7(3):153-69.
Title:	Therapeutic strategy in unresectable metastatic colorectal cancer: an updated review.
Author:	Chibaudel, Benoist\|Tournigand, Christophe\|Bonnetain, Franck\|Richa, Hubert\|Benetkiewicz, Magdalena\|Andre, Thierry\|de Gramont, Aimery
PMID:	26673925

2097.
Journal:	Clin Epigenetics. 2015 Dec 16;7:129.
Title:	MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma-a step towards personalized therapy.
Author:	Garajova, Ingrid\|Funel, Niccola\|Fiorentino, Michelangelo\|Agostini, Valentina\|Ferracin, Manuela\|Negrini, Massimo\|Frassineti, Giovanni Luca\|Gavelli, Giampaolo\|Frampton, Adam Enver\|Biasco, Guido\|Giovannetti, Elisa
PMID:	26677401

2098.
Journal:	PLoS One. 2015 Dec 17;10(12):e0144708.
Title:	Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Author:	Briffa, Romina\|Um, Inhwa\|Faratian, Dana\|Zhou, Ying\|Turnbull, Arran K\|Langdon, Simon P\|Harrison, David J
PMID:	26678268

2099.
Journal:	Rinsho Byori. 2015 Sep;63(9):1091-102.
Title:	[Alternative Splicing Detection as a Biomarker for Cancer Diagnosis: A Novel Progressive Mechanism of Acute Lymphoblastic Leukemia with Alternative Splicing as a Biomarker Candidate].
Author:	Kitamura, Kouichi\|Matsushita, Kazuyuki\|Kobayashi, Souhei\|Ishige, Takayuki\|Semba, Toshihisa\|Kimura, Asako\|Kazami, Takahiro\|Ohyama, Masayuki\|Itoga, Sakae\|Beppu, Minako\|Nishimura, Motoi\|Satoh, Mamoru\|Nomura, Fumio
PMID:	26731899

2100.
Journal:	Clin Lab. 2015;61(11):1635-41.
Title:	Epidermal Growth Factor Receptor Inconsistency by Immunohistochemistry Method Using Different Monoclonal Antibodies in Colorectal Cancer Patients.
Author:	Fan, Chi-Chen\|Wang, Tao-Yeuan\|Kung, Chien-Min
PMID:	26731987

2101.
Journal:	Discov Med. 2015 Dec;20(112):369-78.
Title:	Guanylate-binding protein 1 (GBP1) promotes lymph node metastasis in human esophageal squamous cell carcinoma.
Author:	Li, Lin\|Ma, Gang\|Jing, Chao\|Liu, Zhihua
PMID:	26760981

2102.
Journal:	J Med Liban. 2015 Oct-Dec;63(4):218-27.
Title:	MANAGEMENT OF METASTATIC COLORECTAL CANCER: Current Treatments and New Therapies.
Author:	Henaine, Anna-Maria\|Chahine, Georges\|Salameh, Pascale\|Elias, Edouard\|Massoud, Marcel\|Hartmann, Daniel\|Aulagner, Gilles\|Armoiry, Xavier
PMID:	26821406

2103.
Journal:	Int J Exp Pathol. 2015 Dec;96(6):362-9.
Title:	Multiple pathways regulate Cten in colorectal cancer without a Tensin switch.
Author:	Thorpe, Hannah\|Akhlaq, Maham\|Jackson, Darryl\|Al Ghamdi, Saleh\|Storr, Sarah\|Martin, Stewart\|Ilyas, Mohammad
PMID:	26852686

2104.
Journal:	Rinsho Byori. 2015 Nov;63(11):1310-5.
Title:	[Companion Diagnostics for Solid Tumors].
Author:	Watanabe, Atsushi
PMID:	26995877

2105.
Journal:	Hum Genome Var. 2015 Apr 2;2:15009.
Title:	Pathway activation strength is a novel independent prognostic biomarker for cetuximab sensitivity in colorectal cancer patients.
Author:	Zhu, Qingsong\|Izumchenko, Evgeny\|Aliper, Alexander M\|Makarev, Evgeny\|Paz, Keren\|Buzdin, Anton A\|Zhavoronkov, Alex A\|Sidransky, David
PMID:	27081524

2106.
Journal:	Mol Cell Oncol. 2015 Jan 23;2(4):e1002709.
Title:	BRAF inhibitors in colorectal cancer: Toward a differentiation therapy?
Author:	Herr, Ricarda\|Brummer, Tilman
PMID:	27308494

2107.
Journal:	Head Neck. 2016 Mar;38(3):410-6.
Title:	Assessment of the change in cetuximab-induced antibody-dependent cellular cytotoxicity activity of natural killer cells by steroid.
Author:	Kumai, Takumi\|Oikawa, Kensuke\|Aoki, Naoko\|Kimura, Shoji\|Harabuchi, Yasuaki\|Kobayashi, Hiroya
PMID:	25352398

2108.
Journal:	Cancer Res Treat. 2016 Jan;48(1):355-64.
Title:	Antitumor Activity of HM781-36B, alone or in Combination with Chemotherapeutic Agents, in Colorectal Cancer Cells.
Author:	Kang, Mi Hyun\|Moon, Sung Ung\|Sung, Ji Hea\|Kim, Jin Won\|Lee, Keun Wook\|Lee, Hye Seung\|Lee, Jong Seok\|Kim, Jee Hyun
PMID:	25761479

2109.
Journal:	Gut. 2016 Aug;65(8):1296-305.
Title:	Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer.
Author:	Kloth, Michael\|Ruesseler, Vanessa\|Engel, Christoph\|Koenig, Katharina\|Peifer, Martin\|Mariotti, Erika\|Kuenstlinger, Helen\|Florin, Alexandra\|Rommerscheidt-Fuss, Ursula\|Koitzsch, Ulrike\|Wodtke, Claudia\|Ueckeroth, Frank\|Holzapfel, Stefanie\|Aretz, Stefan\|Proppi
PMID:	26001389

2110.
Journal:	Gen Thorac Cardiovasc Surg. 2016 Dec;64(12):749-751.
Title:	Pulmonary enteric adenocarcinoma.
Author:	Handa, Yoshinori\|Kai, Yuichiro\|Ikeda, Takuhiro\|Mukaida, Hidenori\|Egawa, Hiromi\|Kaneko, Mayumi
PMID:	26139021

2111.
Journal:	Hum Exp Toxicol. 2016 May;35(5):526-43.
Title:	Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.
Author:	Yar Saglam, A S\|Alp, E\|Elmazoglu, Z\|Menevse, S
PMID:	26183715

2112.
Journal:	J Clin Pathol. 2016 Mar;69(3):204-8.
Title:	Correlation between DPYD gene variation and KRAS wild type status in colorectal cancer.
Author:	Kleist, Britta\|Kempa, Marcel\|Meurer, Thuja\|Poetsch, Micaela
PMID:	26281864

2113.
Journal:	Crit Rev Oncol Hematol. 2016 Jan;97:85-95.
Title:	Signaling mechanisms of resistance to EGFR- and Anti-Angiogenic Inhibitors cancer.
Author:	Mirone, Giovanna\|Shukla, Arvind\|Marfe, Gabriella
PMID:	26364891

2114.
Journal:	Tumour Biol. 2016 Feb;37(2):2519-26.
Title:	Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells.
Author:	Tveteraas, Ingun Heiene\|Aasrum, Monica\|Brusevold, Ingvild Johnsen\|Odegard, John\|Christoffersen, Thoralf\|Sandnes, Dagny
PMID:	26386720

2115.
Journal:	Int J Cancer. 2016 Mar 15;138(6):1516-27.
Title:	Combination therapy with zoledronic acid and cetuximab effectively suppresses growth of colorectal cancer cells regardless of KRAS status.
Author:	Kato, Junko\|Futamura, Manabu\|Kanematsu, Masako\|Gaowa, Siqin\|Mori, Ryutaro\|Tanahashi, Toshiyuki\|Matsuhashi, Nobuhisa\|Yoshida, Kazuhiro
PMID:	26437179

2116.
Journal:	J Clin Oncol. 2016 Jan 10;34(2):179-85.
Title:	Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015.
Author:	Allegra, Carmen J\|Rumble, R Bryan\|Hamilton, Stanley R\|Mangu, Pamela B\|Roach, Nancy\|Hantel, Alexander\|Schilsky, Richard L
PMID:	26438111

2117.
Journal:	Clin Exp Metastasis. 2016 Jan;33(1):87-95.
Title:	Potent anti-tumor effects of EGFR-targeted hybrid peptide on mice bearing liver metastases.
Author:	Gaowa, Arong\|Horibe, Tomohisa\|Kohno, Masayuki\|Harada, Hiroshi\|Hiraoka, Masahiro\|Kawakami, Koji
PMID:	26467564

2118.
Journal:	Oncol Rep. 2016 Jan;35(1):107-16.
Title:	Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression.
Author:	Weng, Wen-Hui\|Leung, Wai-Hung\|Pang, Yeu-Jye\|Hsu, Hsi-Hsien
PMID:	26496897

2119.
Journal:	Oncotarget. 2016 Jan 12;7(2):2123-34.
Title:	A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9.
Author:	Goos, Jeroen A C M\|Coupe, Veerle M H\|van de Wiel, Mark A\|Diosdado, Begona\|Delis-Van Diemen, Pien M\|Hiemstra, Annemieke C\|de Cuba, Erienne M V\|Belien, Jeroen A M\|Menke-van der Houven van Oordt, C Willemien\|Geldof, Albert A\|Meijer, Gerrit A\|Hoekstra, Otto S
PMID:	26497206

2120.
Journal:	Surgery. 2016 Mar;159(3):728-35.
Title:	Prognostic factor analysis of circulating tumor cells in peripheral blood of patients with peritoneal carcinomatosis of colon cancer origin treated with cytoreductive surgery plus an intraoperative hyperthermic intraperitoneal chemotherapy procedure (CRS
Author:	Melero, Juan Torres\|Ortega, Francisco G\|Gonzalez, Alvaro Morales\|Carmona-Saez, Pedro\|Garcia Puche, Jose L\|Sugarbaker, Paul H\|Delgado, Miguel\|Lorente, Jose A\|Serrano, Maria Jose
PMID:	26518392

2121.
Journal:	Oncogene. 2016 Jun 16;35(24):3190-200.
Title:	The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.
Author:	Rey, C\|Faustin, B\|Mahouche, I\|Ruggieri, R\|Brulard, C\|Ichas, F\|Soubeyran, I\|Lartigue, L\|De Giorgi, F
PMID:	26522728

2122.
Journal:	Clin Cancer Res. 2016 Mar 1;22(5):1284-94.
Title:	Elevated Coexpression of KITENIN and the ErbB4 CYT-2 Isoform Promotes the Transition from Colon Adenoma to Carcinoma Following APC loss.
Author:	Bae, Jeong A\|Kho, Dhong Hyo\|Sun, Eun Gene\|Ko, Yoo-Seung\|Yoon, Somy\|Lee, Kyung Hwa\|Ahn, Kyu Youn\|Lee, Jae Hyuk\|Joo, Young Eun\|Chung, Ik Joo\|Lee, Sug Hyung\|Kim, Hangun\|Kim, Kyung Keun
PMID:	26527747

2123.
Journal:	Clin Res Hepatol Gastroenterol. 2016 Apr;40(2):154-60.
Title:	Advanced small bowel adenocarcinoma: Molecular characteristics and therapeutic perspectives.
Author:	Zaaimi, Yosra\|Aparicio, Thomas\|Laurent-Puig, Pierre\|Taieb, Julien\|Zaanan, Aziz
PMID:	26547136

2124.
Journal:	Expert Opin Biol Ther. 2016;16(1):93-110.
Title:	Current and advancing treatments for metastatic colorectal cancer.
Author:	Sanz-Garcia, Enrique\|Grasselli, Julieta\|Argiles, Guillem\|Elez, M Elena\|Tabernero, Josep
PMID:	26549053

2125.
Journal:	J Theor Biol. 2016 Jan 21;389:263-73.
Title:	Mathematical modeling of drug resistance due to KRAS mutation in colorectal cancer.
Author:	Sameen, Sheema\|Barbuti, Roberto\|Milazzo, Paolo\|Cerone, Antonio\|Del Re, Marzia\|Danesi, Romano
PMID:	26551156

2126.
Journal:	Int J Colorectal Dis. 2016 Jun;31(6):1245-6.
Title:	HRAS G13D, a new mutation implicated in the resistance to anti-EGFR therapies in colorectal cancer, a case report.
Author:	Boidot, Romain\|Chevrier, Sandy\|Julie, Vincent\|Ladoire, Sylvain\|Ghiringhelli, Francois
PMID:	26561417

2127.
Journal:	Mol Nutr Food Res. 2016 Mar;60(3):519-29.
Title:	Hydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation.
Author:	Terzuoli, Erika\|Giachetti, Antonio\|Ziche, Marina\|Donnini, Sandra
PMID:	26577496

2128.
Journal:	Mol Diagn Ther. 2016 Feb;20(1):65-74.
Title:	KRAS Exon 2 Mutations as Prognostic Indicators in Advanced Colorectal Cancer in Clinical Practice: A Mono-Institutional Study.
Author:	Dadduzio, Vincenzo\|Basso, Michele\|Rossi, Sabrina\|Cenci, Tonia\|Capodimonti, Sara\|Strippoli, Antonia\|Orlandi, Armando\|Cerchiaro, Eleonora\|Schinzari, Giovanni\|Cassano, Alessandra\|Martini, Maurizio\|Barone, Carlo
PMID:	26610798

2129.
Journal:	J Biol Chem. 2016 Jan 29;291(5):2319-30.
Title:	Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES.
Author:	Kado, Yuji\|Mizohata, Eiichi\|Nagatoishi, Satoru\|Iijima, Mariko\|Shinoda, Keiko\|Miyafusa, Takamitsu\|Nakayama, Taisuke\|Yoshizumi, Takuma\|Sugiyama, Akira\|Kawamura, Takeshi\|Lee, Young-Hun\|Matsumura, Hiroyoshi\|Doi, Hirofumi\|Fujitani, Hideaki\|Kodama, Tatsuhiko\|Sh
PMID:	26627827

2130.
Journal:	Yonsei Med J. 2016 Jan;57(1):232-7.
Title:	Relationship between Preoperative (1)(8)F-Fluorodeoxyglucose Uptake and Epidermal Growth Factor Receptor Status in Primary Colorectal Cancer.
Author:	Choi, Yun Jung\|Kim, Min Jeong\|Lee, Bong Hwa\|Kwon, Mi Jung\|Hwang, Hee Sung
PMID:	26632406

2131.
Journal:	Virchows Arch. 2016 Mar;468(3):313-9.
Title:	Microsatellite instability in pulmonary adenocarcinomas: a comprehensive study of 480 cases.
Author:	Warth, Arne\|Korner, Sandrina\|Penzel, Roland\|Muley, Thomas\|Dienemann, Hendrik\|Schirmacher, Peter\|von Knebel-Doeberitz, Magnus\|Weichert, Wilko\|Kloor, Matthias
PMID:	26637197

2132.
Journal:	Cancer Discov. 2016 Feb;6(2):147-153.
Title:	Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer.
Author:	Russo, Mariangela\|Siravegna, Giulia\|Blaszkowsky, Lawrence S\|Corti, Giorgio\|Crisafulli, Giovanni\|Ahronian, Leanne G\|Mussolin, Benedetta\|Kwak, Eunice L\|Buscarino, Michela\|Lazzari, Luca\|Valtorta, Emanuele\|Truini, Mauro\|Jessop, Nicholas A\|Robinson, Hayley E\|H
PMID:	26644315

2133.
Journal:	Oncotarget. 2016 Jan 19;7(3):3453-60.
Title:	HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer.
Author:	Takegawa, Naoki\|Yonesaka, Kimio\|Sakai, Kazuko\|Ueda, Hiroto\|Watanabe, Satomi\|Nonagase, Yoshikane\|Okuno, Tatsuya\|Takeda, Masayuki\|Maenishi, Osamu\|Tsurutani, Junji\|Satoh, Taroh\|Okamoto, Isamu\|Nishio, Kazuto\|Tamura, Takao\|Nakagawa, Kazuhiko
PMID:	26657506

2134.
Journal:	Biochem Biophys Res Commun. 2016 Jan 15;469(3):370-6.
Title:	Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6.
Author:	Penrose, Harrison\|Heller, Sandra\|Cable, Chloe\|Makboul, Rania\|Chadalawada, Gita\|Chen, Ying\|Crawford, Susan E\|Savkovic, Suzana D
PMID:	26657850

2135.
Journal:	Mol Cancer Res. 2016 Mar;14(3):296-301.
Title:	Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF.
Author:	Hechtman, Jaclyn F\|Zehir, Ahmet\|Yaeger, Rona\|Wang, Lu\|Middha, Sumit\|Zheng, Tao\|Hyman, David M\|Solit, David\|Arcila, Maria E\|Borsu, Laetitia\|Shia, Jinru\|Vakiani, Efsevia\|Saltz, Leonard\|Ladanyi, Marc
PMID:	26660078

2136.
Journal:	Target Oncol. 2016 Jun;11(3):363-70.
Title:	Rare RAS Mutations in Metastatic Colorectal Cancer Detected During Routine RAS Genotyping Using Next Generation Sequencing.
Author:	Harle, Alexandre\|Filhine-Tresarrieu, Pierre\|Husson, Marie\|Boidot, Romain\|Rouyer, Marie\|Dubois, Cindy\|Leroux, Agnes\|Merlin, Jean-Louis
PMID:	26661077

2137.
Journal:	Invest New Drugs. 2016 Apr;34(2):168-75.
Title:	A phase I study of selumetinib (AZD6244/ARRY-142866), a MEK1/2 inhibitor, in combination with cetuximab in refractory solid tumors and KRAS mutant colorectal cancer.
Author:	Deming, Dustin A\|Cavalcante, Ludmila L\|Lubner, Sam J\|Mulkerin, Daniel L\|LoConte, Noelle K\|Eickhoff, Jens C\|Kolesar, Jill M\|Fioravanti, Suzanne\|Greten, Tim F\|Compton, Kathryn\|Doyle, Austin G\|Wilding, George\|Duffy, Austin\|Liu, Glenn
PMID:	26666244

2138.
Journal:	Tumour Biol. 2016 Jun;37(6):7295-303.
Title:	A synonymous EGFR polymorphism predicting responsiveness to anti-EGFR therapy in metastatic colorectal cancer patients.
Author:	Bonin, Serena\|Donada, Marisa\|Bussolati, Gianni\|Nardon, Ermanno\|Annaratone, Laura\|Pichler, Martin\|Chiaravalli, Anna Maria\|Capella, Carlo\|Hoefler, Gerald\|Stanta, Giorgio
PMID:	26666825

2139.
Journal:	Int J Mol Med. 2016 Feb;37(2):319-28.
Title:	Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis.
Author:	Shimamoto, Yuji\|Nukatsuka, Mamoru\|Takechi, Teiji\|Fukushima, Masakazu
PMID:	26676887

2140.
Journal:	J Nucl Med. 2016 Mar;57(3):480-5.
Title:	Molecular Fluorescence Endoscopy Targeting Vascular Endothelial Growth Factor A for Improved Colorectal Polyp Detection.
Author:	Tjalma, Jolien J\|Garcia-Allende, P Beatriz\|Hartmans, Elmire\|Terwisscha van Scheltinga, Anton G\|Boersma-van Ek, Wytske\|Glatz, Jurgen\|Koch, Maximilian\|van Herwaarden, Yasmijn J\|Bisseling, Tanya M\|Nagtegaal, Iris D\|Timmer-Bosscha, Hetty\|Koornstra, Jan Jacob\|
PMID:	26678613

2141.
Journal:	J Pathol. 2016 Mar;238(4):562-70.
Title:	HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
Author:	Richman, Susan D\|Southward, Katie\|Chambers, Philip\|Cross, Debra\|Barrett, Jennifer\|Hemmings, Gemma\|Taylor, Morag\|Wood, Henry\|Hutchins, Gordon\|Foster, Joseph M\|Oumie, Assa\|Spink, Karen G\|Brown, Sarah R\|Jones, Marc\|Kerr, David\|Handley, Kelly\|Gray, Richard\|Se
PMID:	26690310

2142.
Journal:	Oncol Rep. 2016 Mar;35(3):1750-6.
Title:	Effects of CD73 on human colorectal cancer cell growth in vivo and in vitro.
Author:	Wu, Ruimin\|Chen, Yijia\|Li, Fuyan\|Li, Wei\|Zhou, Hong\|Yang, Yi\|Pei, Zhijun
PMID:	26708311

2143.
Journal:	Front Biosci (Landmark Ed). 2016 Jan 1;21:410-8.
Title:	Epidermal growth factor receptor-targeted therapy in colorectal cancer.
Author:	Xu, WeiDong\|Jing, HuaYong\|Zhang, FuLi
PMID:	26709782

2144.
Journal:	Oncol Rep. 2016 Feb;35(2):1091-100.
Title:	Pristimerin demonstrates anticancer potential in colorectal cancer cells by inducing G1 phase arrest and apoptosis and suppressing various pro-survival signaling proteins.
Author:	Yousef, Bashir A\|Guerram, Mounia\|Hassan, Hozeifa M\|Hamdi, Aida M\|Zhang, Lu-Yong\|Jiang, Zhen-Zhou
PMID:	26718323

2145.
Journal:	J Natl Cancer Inst. 2015 Dec 30;108(6):djv394.
Title:	Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer.
Author:	Santoro, Valeria\|Jia, Ruochen\|Thompson, Hannah\|Nijhuis, Anke\|Jeffery, Rosemary\|Kiakos, Konstantinos\|Silver, Andrew R\|Hartley, John A\|Hochhauser, Daniel
PMID:	26719345

2146.
Journal:	Drugs. 2016 Feb;76(2):283-9.
Title:	Necitumumab: First Global Approval.
Author:	Garnock-Jones, Karly P
PMID:	26729188

2147.
Journal:	ACS Nano. 2016 Jan 26;10(1):648-62.
Title:	Engineering Chimeric Receptors To Investigate the Size- and Rigidity-Dependent Interaction of PEGylated Nanoparticles with Cells.
Author:	Huang, Wei-Chiao\|Burnouf, Pierre-Alain\|Su, Yu-Cheng\|Chen, Bing-Mae\|Chuang, Kuo-Hsiang\|Lee, Chia-Wei\|Wei, Pei-Kuen\|Cheng, Tian-Lu\|Roffler, Steve R
PMID:	26741147

2148.
Journal:	Jpn J Clin Oncol. 2016 Mar;46(3):228-33.
Title:	A short interval between bevacizumab and anti-epithelial growth factor receptor therapy interferes with efficacy of subsequent anti-EGFR therapy for refractory colorectal cancer.
Author:	Taniguchi, Hiroya\|Komori, Azusa\|Narita, Yukiya\|Kadowaki, Shigenori\|Ura, Takashi\|Andoh, Masashi\|Yatabe, Yasushi\|Komori, Koji\|Kimura, Kenichi\|Kinoshita, Takashi\|Muro, Kei
PMID:	26759349

2149.
Journal:	Oncogenesis. 2016 Jan 18;5:e187.
Title:	Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer.
Author:	Rossner, F\|Gieseler, C\|Morkel, M\|Royer, H-D\|Rivera, M\|Blaker, H\|Dietel, M\|Schafer, R\|Sers, C
PMID:	26779809

2150.
Journal:	Bull Cancer. 2016 Jan;103(1):55-65.
Title:	[What future for circulating tumor DNA? Current data and prospects in colorectal, non-small cell lung and pancreatic cancers].
Author:	Pietrasz, Daniel\|Pecuchet, Nicolas\|Fabre, Elizabeth\|Blons, Helene\|Chevalier, Line\|Taly, Valerie\|Laurent-Puig, Pierre\|Bachet, Jean-Baptiste
PMID:	26790710

2151.
Journal:	J Clin Pathol. 2016 Sep;69(9):767-71.
Title:	Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.
Author:	Malapelle, Umberto\|Pisapia, Pasquale\|Sgariglia, Roberta\|Vigliar, Elena\|Biglietto, Maria\|Carlomagno, Chiara\|Giuffre, Giuseppe\|Bellevicine, Claudio\|Troncone, Giancarlo
PMID:	26797410

2152.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Jan;19(1):22-6.
Title:	[Application of molecular diagnostic techniques in precision medicine of personalized treatment for colorectal cancer].
Author:	Fu, Ji\|Lin, Guole
PMID:	26797832

2153.
Journal:	World J Gastrointest Oncol. 2016 Jan 15;8(1):1-7.
Title:	Clinical efficacy and drug resistance of anti-epidermal growth factor receptor therapy in colorectal cancer.
Author:	Kocoglu, Hakan\|Velibeyoglu, Fatih Mehmet\|Karaca, Mustafa\|Tural, Deniz
PMID:	26798432

2154.
Journal:	Cancer Biol Ther. 2016;17(2):199-207.
Title:	EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile.
Author:	Zhang, Jiayin\|Lu, Biao\|Liu, Dong\|Shen, Ru\|Yan, Yinfa\|Yang, Liuqing\|Zhang, Minsheng\|Zhang, Lei\|Cao, Guoqing\|Cao, Hu\|Fu, Beibei\|Gong, Aishen\|Sun, Qiming\|Wan, Hong\|Zhang, Lianshan\|Tao, Weikang\|Cao, Jingsong
PMID:	26810733

2155.
Journal:	World J Gastroenterol. 2016 Jan 14;22(2):490-500.
Title:	Tropomyosin-related kinase B/brain derived-neurotrophic factor signaling pathway as a potential therapeutic target for colorectal cancer.
Author:	Akil, Hussein\|Perraud, Aurelie\|Jauberteau, Marie-Odile\|Mathonnet, Muriel
PMID:	26811602

2156.
Journal:	World J Gastroenterol. 2016 Jan 14;22(2):887-94.
Title:	Biomarkers of skin toxicity induced by anti-epidermal growth factor receptor antibody treatment in colorectal cancer.
Author:	Kubo, Akiko\|Hashimoto, Hironobu\|Takahashi, Naoki\|Yamada, Yasuhide
PMID:	26811634

2157.
Journal:	PLoS One. 2016 Jan 26;11(1):e0147672.
Title:	Validation of a Multiplex Allele-Specific Polymerase Chain Reaction Assay for Detection of KRAS Gene Mutations in Formalin-Fixed, Paraffin-Embedded Tissues from Colorectal Cancer Patients.
Author:	Seekhuntod, Sirirat\|Thavarungkul, Paninee\|Chaichanawongsaroj, Nuntaree
PMID:	26812617

2158.
Journal:	Cancer Immunol Res. 2016 Apr;4(4):366-74.
Title:	Prospective Evaluation of Cetuximab-Mediated Antibody-Dependent Cell Cytotoxicity in Metastatic Colorectal Cancer Patients Predicts Treatment Efficacy.
Author:	Trotta, Anna Maria\|Ottaiano, Alessandro\|Romano, Carmela\|Nasti, Guglielmo\|Nappi, Anna\|De Divitiis, Chiara\|Napolitano, Maria\|Zanotta, Serena\|Casaretti, Rossana\|D'Alterio, Crescenzo\|Avallone, Antonio\|Califano, Daniela\|Iaffaioli, Rosario Vincenzo\|Scala, Stefa
PMID:	26817995

2159.
Journal:	Oncotarget. 2016 Feb 23;7(8):9309-21.
Title:	Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?
Author:	Derangere, Valentin\|Fumet, Jean David\|Boidot, Romain\|Bengrine, Leila\|Limagne, Emeric\|Chevriaux, Angelique\|Vincent, Julie\|Ladoire, Sylvain\|Apetoh, Lionel\|Rebe, Cedric\|Ghiringhelli, Francois
PMID:	26824184

2160.
Journal:	Clin Cancer Res. 2016 Jun 15;22(12):2897-907.
Title:	Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors.
Author:	Macaulay, Valentine M\|Middleton, Mark R\|Eckhardt, S Gail\|Rudin, Charles M\|Juergens, Rosalyn A\|Gedrich, Richard\|Gogov, Sven\|McCarthy, Sean\|Poondru, Srinivasu\|Stephens, Andrew W\|Gadgeel, Shirish M
PMID:	26831715

2161.
Journal:	Tumour Biol. 2016 May;37(5):5727-34.
Title:	Segmental distribution of some common molecular markers for colorectal cancer (CRC): influencing factors and potential implications.
Author:	Papagiorgis, Petros Christakis
PMID:	26842924

2162.
Journal:	Sci Transl Med. 2016 Feb 3;8(324):324ra14.
Title:	MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations.
Author:	Arena, Sabrina\|Siravegna, Giulia\|Mussolin, Benedetta\|Kearns, Jeffrey D\|Wolf, Beni B\|Misale, Sandra\|Lazzari, Luca\|Bertotti, Andrea\|Trusolino, Livio\|Adjei, Alex A\|Montagut, Clara\|Di Nicolantonio, Federica\|Nering, Rachel\|Bardelli, Alberto
PMID:	26843189

2163.
Journal:	Acta Oncol. 2016 Jul;55(7):875-80.
Title:	HER3 expression is correlated to distally located and low-grade colon cancer.
Author:	Ledel, Frida\|Stenstedt, Kristina\|Hallstrom, Marja\|Ragnhammar, Peter\|Edler, David
PMID:	26863446

2164.
Journal:	BMC Syst Biol. 2016 Feb 11;10:16.
Title:	Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity.
Author:	Pavel, Ana B\|Sonkin, Dmitriy\|Reddy, Anupama
PMID:	26864072

2165.
Journal:	JAMA Oncol. 2016 Feb 11. pii: 2490542.
Title:	Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer.
Author:	Seligmann, Jenny F\|Elliott, Faye\|Richman, Susan D\|Jacobs, Bart\|Hemmings, Gemma\|Brown, Sarah\|Barrett, Jennifer H\|Tejpar, Sabine\|Quirke, Philip\|Seymour, Matthew T
PMID:	26867820

2166.
Journal:	Onco Targets Ther. 2016 Jan 27;9:557-65.
Title:	Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Liu, Jiang\|Hu, Jing\|Cheng, Lei\|Ren, Wei\|Yang, Mi\|Liu, Baorui\|Xie, Li\|Qian, Xiaoping
PMID:	26869800

2167.
Journal:	Iran J Pathol. 2016 Winter;11(1):71-5.
Title:	The Report of KRAS Mutation and NRAS Wild Type in a Patient with Thyroid Metastasis from Colon Cancer: a Rare Case Report.
Author:	Payandeh, Mehrdad\|Sadeghi, Masoud\|Sadeghi, Edris
PMID:	26870147

2168.
Journal:	Oncol Lett. 2016 Jan;11(1):831-836.
Title:	Appropriate use of tumour biomarkers for treatment with innovative drugs: A retrospective study.
Author:	Massa, Ilaria\|Nanni, Oriana\|Guidoboni, Massimo\|Frassineti, Giovanni Luca\|Rocca, Andrea\|Burgio, Marco Angelo\|Valmorri, Linda\|Marri, Mattia\|Piancastelli, Alessandra\|Faedi, Marina\|Leoni, Maurizio\|Tamberi, Stefano\|Altini, Mattia\|Amadori, Dino
PMID:	26870292

2169.
Journal:	Comput Biol Chem. 2016 Apr;61:138-44.
Title:	Design, synthesis and molecular modeling studies of few chalcone analogues of benzimidazole for epidermal growth factor receptor inhibitor in search of useful anticancer agent.
Author:	Chhajed, Santosh S\|Sonawane, Sandeep S\|Upasani, Chandrashekhar D\|Kshirsagar, Sanjay J\|Gupta, Pramodkumar P
PMID:	26878127

2170.
Journal:	Clin Cancer Res. 2016 Jul 1;22(13):3260-7.
Title:	The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer.
Author:	Sanchez-Martin, Francisco J\|Bellosillo, Beatriz\|Gelabert-Baldrich, Mariona\|Dalmases, Alba\|Canadas, Israel\|Vidal, Joana\|Martinez, Alejandro\|Argiles, Guillem\|Siravegna, Giulia\|Arena, Sabrina\|Koefoed, Klaus\|Visa, Laura\|Arpi, Oriol\|Horak, Ivan David\|Iglesias,
PMID:	26888827

2171.
Journal:	Mod Pathol. 2016 Apr;29(4):402-15.
Title:	Clinicopathologic and prognostic associations of KRAS and BRAF mutations in small intestinal adenocarcinoma.
Author:	Jun, Sun-Young\|Kim, Misung\|Jin Gu, Mi\|Kyung Bae, Young\|Chang, Hee-Kyung\|Sun Jung, Eun\|Jang, Kee-Taek\|Kim, Jihun\|Yu, Eunsil\|Woon Eom, Dae\|Hong, Seung-Mo
PMID:	26892442

2172.
Journal:	Cancer Genomics Proteomics. 2016 Mar-Apr;13(2):141-50.
Title:	GeneGazer: A Toolkit Integrating Two Pipelines for Personalized Profiling and Biosignature Identification.
Author:	Luo, Ji-Dung\|Chang, Yu-Jia\|Chang, Chung-Ming\|You, Jeng-Fu\|Wei, Po-Li\|Chiou, Chiuan-Chian
PMID:	26912804

2173.
Journal:	Genes Chromosomes Cancer. 2016 Jun;55(6):505-21.
Title:	Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology.
Author:	Jesinghaus, Moritz\|Pfarr, Nicole\|Endris, Volker\|Kloor, Matthias\|Volckmar, Anna-Lena\|Brandt, Regine\|Herpel, Esther\|Muckenhuber, Alexander\|Lasitschka, Felix\|Schirmacher, Peter\|Penzel, Roland\|Weichert, Wilko\|Stenzinger, Albrecht
PMID:	26917275

2174.
Journal:	Jpn J Clin Oncol. 2016 May;46(5):399-406.
Title:	The possibility of clinical sequencing in the management of cancer.
Author:	Kou, Tadayuki\|Kanai, Masashi\|Matsumoto, Shigemi\|Okuno, Yasushi\|Muto, Manabu
PMID:	26917600

2175.
Journal:	Asian Pac J Cancer Prev. 2016;17(2):539-43.
Title:	Value of KRAS, BRAF, and PIK3CA Mutations and Survival Benefit from Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis.
Author:	Sasaki, Yusuke\|Hamaguchi, Tetsuya\|Yamada, Yasuhide\|Takahashi, Naoki\|Shoji, Hirokazu\|Honma, Yoshitaka\|Iwasa, Satoru\|Okita, Natsuko\|Takashima, Atsuo\|Kato, Ken\|Nagai, Yushi\|Taniguchi, Hirokazu\|Boku, Narikazu\|Ushijima, Toshikazu\|Shimada, Yasuhiro
PMID:	26925640

2176.
Journal:	BioDrugs. 2016 Apr;30(2):95-104.
Title:	Anti-EGFR Therapy for Metastatic Colorectal Cancer in the Era of Extended RAS Gene Mutational Analysis.
Author:	Kassouf, Elie\|Tabchi, Samer\|Tehfe, Mustapha
PMID:	26927802

2177.
Journal:	Cancer Discov. 2016 Apr;6(4):336-7.
Title:	Potential Therapy for Refractory Colon Cancer.
Author:	Leslie, Mitch
PMID:	26928314

2178.
Journal:	Mol Med Rep. 2016 Apr;13(4):3514-20.
Title:	Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer.
Author:	Nagaoka, Tomoko\|Kitaura, Kazutaka\|Miyata, Yukinaga\|Kumagai, Kenichi\|Kaneda, Goro\|Kanazawa, Hideki\|Suzuki, Satsuki\|Hamada, Yoshiki\|Suzuki, Ryuji
PMID:	26935861

2179.
Journal:	Stem Cells Transl Med. 2016 Apr;5(4):511-23.
Title:	Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy Resistance.
Author:	De Angelis, Maria Laura\|Zeuner, Ann\|Policicchio, Eleonora\|Russo, Giorgio\|Bruselles, Alessandro\|Signore, Michele\|Vitale, Sara\|De Luca, Gabriele\|Pilozzi, Emanuela\|Boe, Alessandra\|Stassi, Giorgio\|Ricci-Vitiani, Lucia\|Amoreo, Carla Azzurra\|Pagliuca, Alfredo\|F
PMID:	26956206

2180.
Journal:	Anticancer Res. 2016 Mar;36(3):1093-102.
Title:	Biomarkers in Colorectal Cancer.
Author:	Yiu, Andrew J\|Yiu, Chu Y
PMID:	26977004

2181.
Journal:	Steroids. 2016 Jul;111:63-70.
Title:	The combination of tetraiodothyroacetic acid and cetuximab inhibits cell proliferation in colorectal cancers with different K-ras status.
Author:	Lee, Yee-Shin\|Chin, Yu-Tang\|Yang, Yu-Chen S H\|Wei, Po-Li\|Wu, Han-Chung\|Shih, Ai\|Lu, Yueh-Tong\|Pedersen, Jens Z\|Incerpi, Sandra\|Liu, Leroy F\|Lin, Hung-Yun\|Davis, Paul J
PMID:	26980146

2182.
Journal:	Expert Opin Drug Saf. 2016 Jun;15(6):799-808.
Title:	The safety of monoclonal antibodies for treatment of colorectal cancer.
Author:	Berger, Martin D\|Lenz, Heinz-Josef
PMID:	26982510

2183.
Journal:	MAbs. 2016 May-Jun;8(4):811-27.
Title:	*XGFR, a novel affinity-matured bispecific antibody targeting IGF-1R and EGFR with combined signaling inhibition and enhanced immune activation for the treatment of pancreatic cancer.**
Author:	Schanzer, Juergen M\|Wartha, Katharina\|Moessner, Ekkehard\|Hosse, Ralf J\|Moser, Samuel\|Croasdale, Rebecca\|Trochanowska, Halina\|Shao, Cuiying\|Wang, Peng\|Shi, Lei\|Weinzierl, Tina\|Rieder, Natascha\|Bacac, Marina\|Ries, Carola H\|Kettenberger, Hubert\|Schlothauer,
PMID:	26984378

2184.
Journal:	Mol Diagn Ther. 2016 Jun;20(3):231-40.
Title:	Novel Approach for Clinical Validation of the cobas KRAS Mutation Test in Advanced Colorectal Cancer.
Author:	Sharma, Abha\|Zhang, Guili\|Aslam, Shagufta\|Yu, Karen\|Chee, Melody\|Palma, John F
PMID:	26984642

2185.
Journal:	Ann Occup Environ Med. 2016 Mar 16;28:13.
Title:	Gene mutation discovery research of non-smoking lung cancer patients due to indoor radon exposure.
Author:	Choi, Jung Ran\|Park, Seong Yong\|Noh, O Kyu\|Koh, Young Wha\|Kang, Dae Ryong
PMID:	26985396

2186.
Journal:	PLoS One. 2016 Mar 18;11(3):e0151865.
Title:	BRAF, PIK3CA, and HER2 Oncogenic Alterations According to KRAS Mutation Status in Advanced Colorectal Cancers with Distant Metastasis.
Author:	Nam, Soo Kyung\|Yun, Sumi\|Koh, Jiwon\|Kwak, Yoonjin\|Seo, An Na\|Park, Kyoung Un\|Kim, Duck-Woo\|Kang, Sung-Bum\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	26991109

2187.
Journal:	BMJ Case Rep. 2016 Mar 18;2016. pii: bcr-2016-214582.
Title:	A case of psoriasis pustolosa palmaris induced by cetuximab.
Author:	Marinello, Elena\|Pastorelli, Davide\|Alaibac, Mauro
PMID:	26994052

2188.
Journal:	Cureus. 2016 Feb 3;8(2):e478.
Title:	KDR Mutation as a Novel Predictive Biomarker of Exceptional Response to Regorafenib in Metastatic Colorectal Cancer.
Author:	Loaiza-Bonilla, Arturo\|Jensen, Christopher E\|Shroff, Stuti\|Furth, Emma\|Bonilla-Reyes, Paula A\|Deik, Andres F\|Morrissette, Jennifer
PMID:	27004155

2189.
Journal:	Int J Cancer. 2016 Aug 15;139(4):803-11.
Title:	RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Suenaga, Mitsukuni\|Matsusaka, Satoshi\|Konishi, Tsuyoshi\|Akiyoshi, Takashi\|Fujimoto, Yoshiya\|Nagayama, Satoshi\|Fukunaga, Yosuke\|Ueno, Masashi\|Mise, Yoshihiro\|Ishizawa, Takeaki\|Inoue, Yosuke\|Takahashi, Yu\|Saiura, Akio\|Uehara, H
PMID:	27004837

2190.
Journal:	Nat Rev Gastroenterol Hepatol. 2016 May;13(5):258-9.
Title:	Colorectal cancer: Overcoming resistance to anti-EGFR therapy - where do we stand?
Author:	Schirripa, Marta\|Lenz, Heinz-Josef
PMID:	27006256

2191.
Journal:	Crit Rev Oncol Hematol. 2016 May;101:151-7.
Title:	Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance.
Author:	Temraz, Sally\|Mukherji, Deborah\|Shamseddine, Ali
PMID:	27017409

2192.
Journal:	Arch Pharm Res. 2016 May;39(5):721-9.
Title:	Synergistic inhibitory effect of cetuximab and tectochrysin on human colon cancer cell growth via inhibition of EGFR signal.
Author:	Park, Mi Hee\|Hong, Ji Eun\|Hwang, Chul Ju\|Choi, Mingi\|Choi, Jeong Soon\|An, Young Jin\|Son, Dong Ju\|Hong, Jin Tae
PMID:	27025376

2193.
Journal:	Mol Nutr Food Res. 2016 Sep;60(9):1912-23.
Title:	Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis.
Author:	Kim, Hyemee\|Banerjee, Nivedita\|Ivanov, Ivan\|Pfent, Catherine M\|Prudhomme, Kalan R\|Bisson, William H\|Dashwood, Roderick H\|Talcott, Stephen T\|Mertens-Talcott, Susanne U
PMID:	27028006

2194.
Journal:	Rev Recent Clin Trials. 2016;11(2):93-8.
Title:	What is the Current Role of Immunotherapy for Colon Cancer?
Author:	Galanternik, Fernando\|Recondo, Gonzalo\|Valsecchi, Matias E\|Greco, Martin\|Recondo, Gonzalo\|de la Vega, Maximo\|E Diaz Canton
PMID:	27028968

2195.
Journal:	J Gastrointest Oncol. 2016 Apr;7(Suppl 1):S11-20.
Title:	Molecular testing to optimize therapeutic decision making in advanced colorectal cancer.
Author:	Semrad, Thomas J\|Kim, Edward J
PMID:	27034809

2196.
Journal:	Asian Pac J Cancer Prev. 2016;17(3):1175-9.
Title:	Distribution of KRAS and BRAF Mutations in Metastatic Colorectal Cancers in Turkish Patients.
Author:	Gorukmez, Orhan\|Yakut, Tahsin\|Gorukmez, Ozlem\|Sag, Sebnem Ozemri\|Karkucak, Mutlu\|Kanat, Ozkan
PMID:	27039744

2197.
Journal:	Int J Mol Sci. 2016 Apr 1;17(4):484.
Title:	KRAS G12V Mutation Detection by Droplet Digital PCR in Circulating Cell-Free DNA of Colorectal Cancer Patients.
Author:	Olmedillas Lopez, Susana\|Garcia-Olmo, Dolores C\|Garcia-Arranz, Mariano\|Guadalajara, Hector\|Pastor, Carlos\|Garcia-Olmo, Damian
PMID:	27043547

2198.
Journal:	Q J Nucl Med Mol Imaging. 2016 Apr 5.
Title:	Clinical value of intratumoral metabolic heterogeneity in [18F]FDG PET/CT for prediction of recurrence in patients with locally advanced colorectal cancer.
Author:	Han, Yeon H\|Jeong, Hwan J\|Sohn, Myung H\|Lim, Seok T
PMID:	27045576

2199.
Journal:	Oncotarget. 2016 May 31;7(22):33391-407.
Title:	Treatment outcome of nimotuzumab plus chemotherapy in advanced cancer patients: a single institute experience.
Author:	Xu, Shuping\|Ramos-Suzarte, Mayra\|Bai, Xianhong\|Xu, Binghe
PMID:	27050148

2200.
Journal:	Int J Radiat Oncol Biol Phys. 2016 Jun 1;95(2):663-72.
Title:	Cost-Effectiveness of Surgery, Stereotactic Body Radiation Therapy, and Systemic Therapy for Pulmonary Oligometastases.
Author:	Lester-Coll, Nataniel H\|Rutter, Charles E\|Bledsoe, Trevor J\|Goldberg, Sarah B\|Decker, Roy H\|Yu, James B
PMID:	27055395

2201.
Journal:	Clin Adv Hematol Oncol. 2016 Feb;14(2):116-28.
Title:	A paradigm shift from one-size-fits-all to tailor-made therapy for metastatic colorectal cancer.
Author:	Weinberg, Benjamin A\|Marshall, John L\|Hartley, Marion\|Salem, Mohamed E
PMID:	27057810

2202.
Journal:	J BUON. 2016 Jan-Feb;21(1):95-100.
Title:	Detection of EGFR expression in patients with colorectal cancer and the therapeutic effect of cetuximab.
Author:	Liu, Jinbo\|Zhou, Quanbo\|Xu, Jizhong\|Wang, Jiaxiang\|Zhang, Yi
PMID:	27061536

2203.
Journal:	Cancer Biomark. 2016;16(3):435-44.
Title:	Multiple differential expression networks identify key genes in rectal cancer.
Author:	Li, Ri-Heng\|Zhang, Ai-Min\|Li, Shuang\|Li, Tian-Yang\|Wang, Lian-Jing\|Zhang, Hao-Ran\|Li, Ping\|Jia, Xiong-Jie\|Zhang, Tao\|Peng, Xin-Yu\|Liu, Min-Di\|Wang, Xu\|Lang, Yan\|Xue, Wei-Lan\|Liu, Jing\|Wang, Yan-Yan
PMID:	27062700

2204.
Journal:	PLoS One. 2016 Apr 11;11(4):e0153278.
Title:	Heterogeneity of KRAS Mutation Status in Rectal Cancer.
Author:	Jo, Peter\|Konig, Alexander\|Schirmer, Markus\|Kitz, Julia\|Conradi, Lena-Christin\|Azizian, Azadeh\|Bernhardt, Markus\|Wolff, Hendrik A\|Grade, Marian\|Ghadimi, Michael\|Strobel, Philipp\|Schildhaus, Hans-Ulrich\|Gaedcke, Jochen
PMID:	27064574

2205.
Journal:	Gan To Kagaku Ryoho. 2016 Feb;43(2):229-33.
Title:	[Relationship between the Incidence of Hypomagnesemia and Acneiform Rash and the Therapeutic Effect of Anti-EGFR Monoclonal Antibody in Patients with Metastatic Colorectal Cancer].
Author:	Fujii, Hironori\|Iihara, Hirotoshi\|Ishihara, Masashi\|Matsuhashi, Nobuhisa\|Takahashi, Takao\|Yoshida, Kazuhiro\|Itoh, Yoshinori
PMID:	27067688

2206.
Journal:	Gan To Kagaku Ryoho. 2016 Mar;43(3):377-9.
Title:	[A Case of an Unresectable Locally Advanced Rectal Cancer with Surrounding Organ Invasion Successfully Resected after Chemotherapy with mFOLFOX6 plus Cetuximab].
Author:	Takagi, Hironori\|Ariake, Kyohei\|Takemura, Shinichi\|Doi, Takashi
PMID:	27067860

2207.
Journal:	Anticancer Res. 2016 Apr;36(4):1571-9.
Title:	Rapid and Specific Screening Assay for KRAS Oncogene Mutation by a Novel Gene Amplification Method.
Author:	Kumasaka, Akira\|Matsumoto, Naoyuki\|Mukae, Shotaro\|Kitano, Taiichi\|Noguchi, Hiroyasu\|Ohki, Hidero\|Komiyama, Kazuo\|Ando, Tomohiro
PMID:	27069133

2208.
Journal:	Oncotarget. 2016 Oct 4;7(40):64766-64777.
Title:	Identification and validation of COX-2 as a co-target for overcoming cetuximab resistance in colorectal cancer cells.
Author:	Lu, Yang\|Shi, Chunmei\|Qiu, Songbo\|Fan, Zhen
PMID:	27074568

2209.
Journal:	Sci Rep. 2016 Apr 14;6:24310.
Title:	Prognostic impact of mutation profiling in patients with stage II and III colon cancer.
Author:	Shen, Yinchen\|Han, Xiaohong\|Wang, Jianfei\|Wang, Shuai\|Yang, Hongying\|Lu, Shih-Hsin\|Shi, Yuankai
PMID:	27074743

2210.
Journal:	World J Gastroenterol. 2016 Apr 14;22(14):3758-68.
Title:	Evaluation of therapeutic effectiveness of (131)I-antiEGFR-BSA-PCL in a mouse model of colorectal cancer.
Author:	Li, Wei\|Ji, Yan-Hui\|Li, Cheng-Xia\|Liu, Zhong-Yun\|Li, Ning\|Fang, Lei\|Chang, Jin\|Tan, Jian
PMID:	27076760

2211.
Journal:	BMC Cancer. 2016 Apr 14;16:271.
Title:	Comparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia.
Author:	Shivakumar, B M\|Chakrabarty, Sanjiban\|Rotti, Harish\|Seenappa, Venu\|Rao, Lakshmi\|Geetha, Vasudevan\|Tantry, B V\|Kini, Hema\|Dharamsi, Rajesh\|Pai, C Ganesh\|Satyamoorthy, Kapaettu
PMID:	27080994

2212.
Journal:	Bioorg Med Chem Lett. 2016 Jun 1;26(11):2685-90.
Title:	Computer-aided design, synthesis, and biological evaluation of new indole-2-carboxamide derivatives as PI3Kalpha/EGFR inhibitors.
Author:	Sweidan, Kamal\|Sabbah, Dima A\|Bardaweel, Sanaa\|Dush, Khadeja Abu\|Sheikha, Ghassan Abu\|Mubarak, Mohammad S
PMID:	27084677

2213.
Journal:	Biochim Biophys Acta. 2016 Jul;1861(7):663-70.
Title:	Deoxycholic acid mediates non-canonical EGFR-MAPK activation through the induction of calcium signaling in colon cancer cells.
Author:	Centuori, Sara M\|Gomes, Cecil J\|Trujillo, Jesse\|Borg, Jamie\|Brownlee, Joshua\|Putnam, Charles W\|Martinez, Jesse D
PMID:	27086143

2214.
Journal:	Sci Rep. 2016 Apr 19;6:24572.
Title:	Oncolytic Activity of a Recombinant Measles Virus, Blind to Signaling Lymphocyte Activation Molecule, Against Colorectal Cancer Cells.
Author:	Amagai, Yosuke\|Fujiyuki, Tomoko\|Yoneda, Misako\|Shoji, Koichiro\|Furukawa, Yoichi\|Sato, Hiroki\|Kai, Chieko
PMID:	27090874

2215.
Journal:	Nutr Cancer. 2016;68(3):495-506.
Title:	Ethanolic Extract of Bark from Salix aegyptiaca Ameliorates 1,2-dimethylhydrazine-induced Colon Carcinogenesis in Mice by Reducing Oxidative Stress.
Author:	Bounaama, Abdelkader\|Enayat, Shabnam\|Ceyhan, Muserref Seyma\|Moulahoum, Hichem\|Djerdjouri, Bahia\|Banerjee, Sreeparna
PMID:	27093594

2216.
Journal:	Sci Rep. 2016 Apr 20;6:24720.
Title:	miRs-134 and -370 function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling.
Author:	El-Daly, Sherien M\|Abba, Mohammed L\|Patil, Nitin\|Allgayer, Heike
PMID:	27095166

2217.
Journal:	Onco Targets Ther. 2016 Mar 31;9:1899-920.
Title:	Advances in targeted and immunobased therapies for colorectal cancer in the genomic era.
Author:	Seow, Heng Fong\|Yip, Wai Kien\|Fifis, Theodora
PMID:	27099521

2218.
Journal:	PLoS One. 2016 Apr 21;11(4):e0154038.
Title:	Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.
Author:	Froyen, Guy\|Broekmans, An\|Hillen, Femke\|Pat, Karin\|Achten, Ruth\|Mebis, Jeroen\|Rummens, Jean-Luc\|Willemse, Johan\|Maes, Brigitte
PMID:	27101000

2219.
Journal:	Oncotarget. 2016 Jun 14;7(24):36168-36184.
Title:	SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Author:	Gueguinou, Maxime\|Harnois, Thomas\|Crottes, David\|Uguen, Arnaud\|Deliot, Nadine\|Gambade, Audrey\|Chantome, Aurelie\|Haelters, Jean Pierre\|Jaffres, Paul Alain\|Jourdan, Marie Lise\|Weber, Gunther\|Soriani, Olivier\|Bougnoux, Philippe\|Mignen, Olivier\|Bourmeyster, N
PMID:	27102434

2220.
Journal:	J Clin Pathol. 2016 Apr 22. pii: jclinpath-2016-203638.
Title:	Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
Author:	Chen, Yi-Ting\|Tsao, Shu-Chuan\|Tsai, Hung-Pei\|Wang, Jaw-Yuan\|Chai, Chee-Yin
PMID:	27107100

2221.
Journal:	Oncotarget. 2016 May 17;7(20):29429-39.
Title:	Pinin facilitated proliferation and metastasis of colorectal cancer through activating EGFR/ERK signaling pathway.
Author:	Wei, Zhigang\|Ma, Wenhui\|Qi, Xiaolong\|Zhu, Xianjun\|Wang, Yutian\|Xu, Zhuoluo\|Luo, Jun\|Wang, Da\|Guo, Weihong\|Li, Xiaomei\|Xin, Sainan\|Yu, Jiang\|Li, Guoxin
PMID:	27107420

2222.
Journal:	Cancer Sci. 2016 Jul;107(7):936-43.
Title:	Utility of KRAS mutation detection using circulating cell-free DNA from patients with colorectal cancer.
Author:	Yamada, Takeshi\|Iwai, Takuma\|Takahashi, Goro\|Kan, Hayato\|Koizumi, Michihiro\|Matsuda, Akihisa\|Shinji, Seiichi\|Yamagishi, Aya\|Yokoyama, Yasuyuki\|Tatsuguchi, Atsushi\|Kawagoe, Tatsuro\|Kitano, Shiro\|Nakayama, Masato\|Matsumoto, Satoshi\|Uchida, Eiji
PMID:	27116474

2223.
Journal:	Oncotarget. 2016 May 17;7(20):29492-506.
Title:	Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling.
Author:	Owusu, Benjamin Y\|Bansal, Namita\|Venukadasula, Phanindra K M\|Ross, Larry J\|Messick, Troy E\|Goel, Sanjay\|Galemmo, Robert A\|Klampfer, Lidija
PMID:	27121052

2224.
Journal:	Nat Med. 2016 Jun;22(6):624-31.
Title:	The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death.
Author:	Pozzi, Chiara\|Cuomo, Alessandro\|Spadoni, Ilaria\|Magni, Elena\|Silvola, Alessio\|Conte, Alexia\|Sigismund, Sara\|Ravenda, Paola Simona\|Bonaldi, Tiziana\|Zampino, Maria Giulia\|Cancelliere, Carlotta\|Di Fiore, Pier Paolo\|Bardelli, Alberto\|Penna, Giuseppe\|Rescigno,
PMID:	27135741

2225.
Journal:	Br J Radiol. 2016 Jul;89(1063):20160212.
Title:	(18)F-FDG PET/CT imaging in rectal cancer: relationship with the RAS mutational status.
Author:	Lovinfosse, Pierre\|Koopmansch, Benjamin\|Lambert, Frederic\|Jodogne, Sebastien\|Kustermans, Gaelle\|Hatt, Mathieu\|Visvikis, Dimitris\|Seidel, Laurence\|Polus, Marc\|Albert, Adelin\|Delvenne, Philippe\|Hustinx, Roland
PMID:	27146067

2226.
Journal:	J Transl Med. 2016 May 4;14(1):118.
Title:	Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.
Author:	Dallol, Ashraf\|Buhmeida, Abdelbaset\|Al-Ahwal, Mahmoud Shaheen\|Al-Maghrabi, Jaudah\|Bajouh, Osama\|Al-Khayyat, Shadi\|Alam, Rania\|Abusanad, Atlal\|Turki, Rola\|Elaimi, Aisha\|Alhadrami, Hani A\|Abuzenadah, Mohammed\|Banni, Huda\|Al-Qahtani, Mohammed H\|Abuzenadah, A
PMID:	27146902

2227.
Journal:	Acta Dermatovenerol Croat. 2016 Apr;24(1):70-2.
Title:	Adverse Reaction to Cetuximab, an Epidermal Growth Factor Receptor Inhibitor.
Author:	Stulhofer Buzina, Daska\|Martinac, Ivana\|Ledic Drvar, Daniela\|Ceovic, Romana\|Bilic, Ivan\|Marinovic, Branka
PMID:	27149134

2228.
Journal:	Am J Transl Res. 2016 Feb 15;8(2):1190-6. eCollection 2016.
Title:	Colorectal cancer cells are resistant to anti-EGFR monoclonal antibody through adapted autophagy.
Author:	Chen, Zhi\|Gao, Shuohui\|Wang, Dayv\|Song, Defeng\|Feng, Ye
PMID:	27158405

2229.
Journal:	Eur Urol. 2016 Nov;70(5):771-775.
Title:	Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition.
Author:	Collazo-Lorduy, Ana\|Castillo-Martin, Mireia\|Wang, Li\|Patel, Vaibhav\|Iyer, Gopa\|Jordan, Emmet\|Al-Ahmadie, Hikmat\|Leonard, Issa\|Oh, William K\|Zhu, Jun\|McBride, Russell B\|Cordon-Cardo, Carlos\|Solit, David B\|Sfakianos, John P\|Galsky, Matthew D
PMID:	27178450

2230.
Journal:	Clin Cancer Res. 2016 May 15;22(10):2435-44.
Title:	Fc-gamma Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.
Author:	Liu, Geoffrey\|Tu, Dongsheng\|Lewis, Marcia\|Cheng, Dangxiao\|Sullivan, Leslie A\|Chen, Zhuo\|Morgen, Eric\|Simes, John\|Price, Timothy J\|Tebbutt, Niall C\|Shapiro, Jeremy D\|Jeffery, G Mark\|Mellor, J Daniel\|Mikeska, Thomas\|Virk, Shakeel\|Shepherd, Lois E\|Jonker, De
PMID:	27179112

2231.
Journal:	Pol J Pathol. 2016 Mar;67(1):13-8.
Title:	Concordance of KRAS mutation status between luminal and peripheral regions of primary colorectal cancer. A laser-capture microdissection-based study.
Author:	Lewandowska, M\|Hybiak, J\|Domagala, W
PMID:	27179269

2232.
Journal:	Mol Cancer Ther. 2016 Jul;15(7):1525-34.
Title:	The Discovery and Characterization of K-756, a Novel Wnt/beta-Catenin Pathway Inhibitor Targeting Tankyrase.
Author:	Okada-Iwasaki, Ryoko\|Takahashi, Yuichi\|Watanabe, Yasuo\|Ishida, Hiroshi\|Saito, Jun-Ichi\|Nakai, Ryuichiro\|Asai, Akira
PMID:	27196752

2233.
Journal:	J Nat Sci. 2016;2(1).
Title:	Pharmacokinetic, biodistribution and therapeutic efficacy of 5-fluorouracil-loaded pH-sensitive PEGylated liposomal nanoparticles in HCT-116 tumor bearing mouse.
Author:	Udofot, Ofonime\|Affram, Kevin\|Smith, Taylor\|Tshabe, Bulumko\|Krishnan, Sunil\|Sachdeva, Mandip\|Agyare, Edward
PMID:	27200415

2234.
Journal:	Carcinogenesis. 2016 Jul;37(7):731-739.
Title:	Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Author:	Tao, Yun\|Messer, Jeannette S\|Goss, Kathleen H\|Hart, John\|Bissonnette, Marc\|Chang, Eugene B
PMID:	27207671

2235.
Journal:	Gan To Kagaku Ryoho. 2016 May;43(5):633-5.
Title:	[A Case of Advanced Colon Cancer with Long-Term and Re-Administration of Regorafenib].
Author:	Funakoshi, Tohru\|Kato, Takuya\|Kuratani, Yuki\|Yamada, Kenji\|Kenno, Sachiko\|Shibaki, Taiichiro\|Yanagida, Naoyuki\|Inagaki, Mitsuhiro\|Ikeue, Sunao\|Akabane, Hiromitsu\|Nakano, Shiro
PMID:	27210098

2236.
Journal:	Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title:	Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author:	Pfarr, Nicole\|Penzel, Roland\|Klauschen, Frederick\|Heim, Daniel\|Brandt, Regine\|Kazdal, Daniel\|Jesinghaus, Moritz\|Herpel, Esther\|Schirmacher, Peter\|Warth, Arne\|Weichert, Wilko\|Endris, Volker\|Stenzinger, Albrecht
PMID:	27218826

2237.
Journal:	Tumour Biol. 2016 Sep;37(9):12153-12160.
Title:	SH3GL1 inhibition reverses multidrug resistance in colorectal cancer cells by downregulation of MDR1/P-glycoprotein via EGFR/ERK/AP-1 pathway.
Author:	Guan, Haitao\|Zhao, Ping\|Dai, Zhijun\|Liu, Xiaoxu\|Wang, Xijing
PMID:	27220321

2238.
Journal:	Asian Pac J Cancer Prev. 2016;17(4):1729-32.
Title:	Correlation between RAS Test Results and Prognosis of Metastatic Colorectal Cancer Patients: a Report from Western Iran.
Author:	Payandeh, Mehrdad\|Shazad, Babak\|Sadeghi, Masoud\|Shahbazi, Maryam
PMID:	27221845

2239.
Journal:	BMC Cancer. 2016 May 31;16:339.
Title:	ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours.
Author:	Segelov, Eva\|Waring, Paul\|Desai, Jayesh\|Wilson, Kate\|Gebski, Val\|Thavaneswaran, Subotheni\|Elez, Elena\|Underhill, Craig\|Pavlakis, Nick\|Chantrill, Lorraine\|Nott, Louise\|Jefford, Michael\|Khasraw, Mustafa\|Day, Fiona\|Wasan, Harpreet\|Ciardiello, Fortunato\|Karap
PMID:	27246726

2240.
Journal:	Oncogene. 2016 Dec 15;35(50):6403-6415.
Title:	Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter.
Author:	Qu, X\|Sandmann, T\|Frierson, H Jr\|Fu, L\|Fuentes, E\|Walter, K\|Okrah, K\|Rumpel, C\|Moskaluk, C\|Lu, S\|Wang, Y\|Bourgon, R\|Penuel, E\|Pirzkall, A\|Amler, L\|Lackner, M R\|Tabernero, J\|Hampton, G M\|Kabbarah, O
PMID:	27270421

2241.
Journal:	Med Oncol. 2016 Jul;33(7):71.
Title:	Comparison of KRAS mutation status between primary tumor and metastasis in Chinese colorectal cancer patients.
Author:	Li, Zhe-Zhen\|Bai, Long\|Wang, Feng\|Zhang, Zi-Chen\|Wang, Fang\|Zeng, Zhao-Lei\|Zeng, Jun-Bo\|Zhang, Dong-Sheng\|Wang, Feng-Hua\|Wang, Zhi-Qiang\|Li, Yu-Hong\|Shao, Jian-Yong\|Xu, Rui-Hua
PMID:	27270901

2242.
Journal:	Br J Cancer. 2016 Jun 14;114(12):1352-61.
Title:	Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.
Author:	Lee, Michael S\|McGuffey, Elizabeth J\|Morris, Jeffrey S\|Manyam, Ganiraju\|Baladandayuthapani, Veerabahdran\|Wei, Wei\|Morris, Van K\|Overman, Michael J\|Maru, Dipen M\|Jiang, Zhi-Qin\|Hamilton, Stanley R\|Kopetz, Scott
PMID:	27272216

2243.
Journal:	PLoS One. 2016 Jun 8;11(6):e0156540.
Title:	Terpinen-4-ol: A Novel and Promising Therapeutic Agent for Human Gastrointestinal Cancers.
Author:	Shapira, Shiran\|Pleban, Shlomo\|Kazanov, Diana\|Tirosh, Peter\|Arber, Nadir
PMID:	27275783

2244.
Journal:	Oncotarget. 2016 Jun 28;7(26):39293-39301.
Title:	Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance.
Author:	Modos, Orsolya\|Reis, Henning\|Niedworok, Christian\|Rubben, Herbert\|Szendroi, Attila\|Szasz, Marcell A\|Timar, Jozsef\|Baghy, Kornelia\|Kovalszky, Ilona\|Golabek, Tomasz\|Chlosta, Piotr\|Okon, Krzysztof\|Peyronnet, Benoit\|Mathieu, Romain\|Shariat, Shahrokh F\|Hollosi
PMID:	27283768

2245.
Journal:	Mol Clin Oncol. 2016 Jun;4(6):1017-1024.
Title:	Efficacy of cetuximab-based chemotherapy in metastatic colorectal cancer according to RAS and BRAF mutation subgroups: A meta-analysis.
Author:	Lin, L I\|Chen, Lu-Lu\|Wang, You\|Meng, Xiang-Yu\|Liang, Chen\|Zhou, Fu-Xiang
PMID:	27284437

2246.
Journal:	BMC Cancer. 2016 Jun 13;16:366.
Title:	PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study.
Author:	Kuramochi, Hidekazu\|Nakamura, Ayako\|Nakajima, Go\|Kaneko, Yuka\|Araida, Tatsuo\|Yamamoto, Masakazu\|Hayashi, Kazuhiko
PMID:	27296289

2247.
Journal:	Oncotarget. 2016 Jul 5;7(27):42225-42240.
Title:	Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC).
Author:	Zhang, Tiening\|Cai, Xun\|Li, Qi\|Xue, Peng\|Chen, Zhixiao\|Dong, Xiao\|Xue, Ying
PMID:	27302926

2248.
Journal:	Mol Oncol. 2016 Oct;10(8):1221-31.
Title:	Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery.
Author:	Denis, Jerome Alexandre\|Patroni, Alexia\|Guillerm, Erell\|Pepin, Dominique\|Benali-Furet, Naoual\|Wechsler, Janine\|Manceau, Gilles\|Bernard, Maguy\|Coulet, Florence\|Larsen, Annette K\|Karoui, Mehdi\|Lacorte, Jean-Marc
PMID:	27311775

2249.
Journal:	Cancer Res. 2016 Aug 1;76(15):4504-15.
Title:	Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer.
Author:	Oddo, Daniele\|Sennott, Erin M\|Barault, Ludovic\|Valtorta, Emanuele\|Arena, Sabrina\|Cassingena, Andrea\|Filiciotto, Genny\|Marzolla, Giulia\|Elez, Elena\|van Geel, Robin M J M\|Bartolini, Alice\|Crisafulli, Giovanni\|Boscaro, Valentina\|Godfrey, Jason T\|Buscarino, M
PMID:	27312529

2250.
Journal:	PLoS One. 2016 Jun 17;11(6):e0157830.
Title:	Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer.
Author:	Veluchamy, John Pradeep\|Spanholtz, Jan\|Tordoir, Marleen\|Thijssen, Victor L\|Heideman, Danielle A M\|Verheul, Henk M W\|de Gruijl, Tanja D\|van der Vliet, Hans J
PMID:	27314237

2251.
Journal:	Genet Mol Res. 2016 May 23;15(2). pii: gmr8365.
Title:	Construction of a protein-protein interaction network of Wilms' tumor and pathway prediction of molecular complexes.
Author:	Teng, W J\|Zhou, C\|Liu, L J\|Cao, X J\|Zhuang, J\|Liu, G X\|Sun, C G
PMID:	27323086

2252.
Journal:	Cancer Discov. 2016 Sep;6(9):963-71.
Title:	MET-Driven Resistance to Dual EGFR and BRAF Blockade May Be Overcome by Switching from EGFR to MET Inhibition in BRAF-Mutated Colorectal Cancer.
Author:	Pietrantonio, Filippo\|Oddo, Daniele\|Gloghini, Annunziata\|Valtorta, Emanuele\|Berenato, Rosa\|Barault, Ludovic\|Caporale, Marta\|Busico, Adele\|Morano, Federica\|Gualeni, Ambra Vittoria\|Alessi, Alessandra\|Siravegna, Giulia\|Perrone, Federica\|Di Bartolomeo, Maria\|
PMID:	27325282

2253.
Journal:	Br J Cancer. 2016 Jun 28;115(1):40-51.
Title:	FAT1: a potential target for monoclonal antibody therapy in colon cancer.
Author:	Pileri, Piero\|Campagnoli, Susanna\|Grandi, Alberto\|Parri, Matteo\|De Camilli, Elisa\|Song, Chaojun\|Ganfini, Luisa\|Lacombe, Aurelien\|Naldi, Ilaria\|Sarmientos, Paolo\|Cinti, Caterina\|Jin, Boquan\|Grandi, Guido\|Viale, Giuseppe\|Terracciano, Luigi\|Grifantini, Renat
PMID:	27328312

2254.
Journal:	Dig Dis. 2016;34(5):574-9.
Title:	Therapeutic Strategies in Diseases of the Digestive Tract - 2015 and Beyond Targeted Therapies in Colon Cancer Today and Tomorrow.
Author:	Pohl, Michael\|Schmiegel, Wolff
PMID:	27332557

2255.
Journal:	Biomol Detect Quantif. 2016 Jun 6;8:29-32.
Title:	Diagnostic RAS mutation analysis by polymerase chain reaction (PCR).
Author:	Cree, Ian A
PMID:	27335808

2256.
Journal:	World J Gastroenterol. 2016 Jun 21;22(23):5332-41.
Title:	Treatment dilemmas of cetuximab combined with chemotherapy for metastatic colorectal cancer.
Author:	Wen, Feng\|Li, Qiu
PMID:	27340349

2257.
Journal:	Cancer J. 2016 May-Jun;22(3):149-55.
Title:	Spectrum of Gene Mutations in Colorectal Cancer: Implications for Treatment.
Author:	Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	27341591

2258.
Journal:	Cancer Chemother Pharmacol. 2016 Aug;78(2):397-403.
Title:	Panitumumab in combination with irinotecan plus S-1 (IRIS) as second-line therapy for metastatic colorectal cancer.
Author:	Takaoka, Toshi\|Kimura, Tetsuo\|Shimoyama, Rai\|Kawamoto, Shunji\|Sakamoto, Kazuki\|Goda, Fuminori\|Miyamoto, Hiroshi\|Negoro, Yuji\|Tsuji, Akihito\|Yoshizaki, Koji\|Goji, Takahiro\|Kitamura, Shinji\|Yano, Hiromi\|Okamoto, Koichi\|Kimura, Masako\|Okahisa, Toshiya\|Muguru
PMID:	27342247

2259.
Journal:	Oncotarget. 2016 Aug 23;7(34):55890-55899.
Title:	Prognostic value of amphiregulin and epiregulin mRNA expression in metastatic colorectal cancer patients.
Author:	Jing, Chen\|Jin, Yang Han\|You, Zhai\|Qiong, Qian\|Jun, Zhou
PMID:	27344184

2260.
Journal:	J Extracell Vesicles. 2016 Jun 24;5:29254.
Title:	Identification and characterization of EGF receptor in individual exosomes by fluorescence-activated vesicle sorting.
Author:	Higginbotham, James N\|Zhang, Qin\|Jeppesen, Dennis K\|Scott, Andrew M\|Manning, H Charles\|Ochieng, Josiah\|Franklin, Jeffrey L\|Coffey, Robert J
PMID:	27345057

2261.
Journal:	Anticancer Res. 2016 Jul;36(7):3781-8.
Title:	Nuclear Y-Box-binding Protein-1 Expression Predicts Poor Clinical Outcome in Stage III Colorectal Cancer.
Author:	Shiraiwa, Sachiko\|Kinugasa, Tetsushi\|Kawahara, Akihiko\|Mizobe, Tomoaki\|Ohchi, Takafumi\|Yuge, Kotaro\|Fujino, Shinya\|Katagiri, Mitsuhiro\|Shimomura, Susumu\|Tajiri, Kensuke\|Sudo, Tomoya\|Kage, Masayoshi\|Kuwano, Michihiko\|Akagi, Yoshito
PMID:	27354655

2262.
Journal:	Cancer Res. 2016 Sep 1;76(17):5019-29.
Title:	Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody.
Author:	Pupo, Emanuela\|Ducano, Nadia\|Lupo, Barbara\|Vigna, Elisa\|Avanzato, Daniele\|Perera, Timothy\|Trusolino, Livio\|Lanzetti, Letizia\|Comoglio, Paolo M
PMID:	27364553

2263.
Journal:	Pharmacol Ther. 2016 Oct;166:71-83.
Title:	Preclinical and clinical studies on afatinib in monotherapy and in combination regimens: Potential impact in colorectal cancer.
Author:	De Pauw, I\|Wouters, A\|Van den Bossche, J\|Peeters, M\|Pauwels, P\|Deschoolmeester, V\|Vermorken, J B\|Lardon, F
PMID:	27373506

2264.
Journal:	Oncologist. 2016 Aug;21(8):988-94.
Title:	Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer.
Author:	Moretto, Roberto\|Cremolini, Chiara\|Rossini, Daniele\|Pietrantonio, Filippo\|Battaglin, Francesca\|Mennitto, Alessia\|Bergamo, Francesca\|Loupakis, Fotios\|Marmorino, Federica\|Berenato, Rosa\|Marsico, Valentina Angela\|Caporale, Marta\|Antoniotti, Carlotta\|Masi, Gi
PMID:	27382031

2265.
Journal:	Biochim Biophys Acta. 2016 Aug;1866(1):106-20.
Title:	DNA methylation based biomarkers in colorectal cancer: A systematic review.
Author:	Lam, Kevin\|Pan, Kathy\|Linnekamp, Janneke Fiona\|Medema, Jan Paul\|Kandimalla, Raju
PMID:	27385266

2266.
Journal:	Diagn Pathol. 2016 Jul 8;11(1):61.
Title:	In depth evaluation of the prognostic and predictive utility of PTEN immunohistochemistry in colorectal carcinomas: performance of three antibodies with emphasis on intracellular and intratumoral heterogeneity.
Author:	Agoston, Emese Irma\|Micsik, Tamas\|Acs, Balazs\|Fekete, Krisztina\|Hahn, Oszkar\|Baranyai, Zsolt\|Dede, Kristof\|Bodoky, Gyorgy\|Bursics, Attila\|Kulka, Janina\|Krenacs, Tibor\|Gyorffy, Balazs\|Harsanyi, Laszlo\|Szasz, A Marcell
PMID:	27392434

2267.
Journal:	Oncogenesis. 2016 Jul 11;5(7):e240.
Title:	Expression of the chemokine CXCL14 and cetuximab-dependent tumour suppression in head and neck squamous cell carcinoma.
Author:	Kondo, T\|Ozawa, S\|Ikoma, T\|Yang, X-Y\|Kanamori, K\|Suzuki, K\|Iwabuchi, H\|Maehata, Y\|Miyamoto, C\|Taguchi, T\|Kiyono, T\|Kubota, E\|Hata, R-I
PMID:	27399917

2268.
Journal:	BMC Cancer. 2016 Jul 12;16:454.
Title:	Highly sensitive detection of the PIK3CA (H1047R) mutation in colorectal cancer using a novel PCR-RFLP method.
Author:	Li, Wan-Ming\|Hu, Ting-Ting\|Zhou, Lin-Lin\|Feng, Yi-Ming\|Wang, Yun-Yi\|Fang, Jin
PMID:	27405731

2269.
Journal:	Oncotarget. 2016 Aug 2;7(31):50575-50581.
Title:	Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature.
Author:	Guo, Sheng\|Chen, Dawei\|Huang, Xuesong\|Cai, Jie\|Wery, Jean-Pierre\|Li, Qi-Xiang
PMID:	27409671

2270.
Journal:	J Pharm Biomed Anal. 2016 Sep 10;129:142-147.
Title:	Determination of a novel B-Raf(V600E) and EGFR dual inhibitor in rat plasma by HPLC-MS/MS and its application in a pharmacokinetic study.
Author:	Zhou, Zhi-Ling\|Deng, Ji-Feng\|Li, Ying-Jun\|Chang, Yu\|Cheng, Hui-Min
PMID:	27423011

2271.
Journal:	Int J Clin Oncol. 2016 Dec;21(6):1091-1101.
Title:	CpG island methylator phenotype is associated with the efficacy of sequential oxaliplatin- and irinotecan-based chemotherapy and EGFR-related gene mutation in Japanese patients with metastatic colorectal cancer.
Author:	Zhang, Xiaofei\|Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Takahashi, Hidekazu\|Ouchi, Kota\|Inoue, Masahiro\|Takahashi, Masanobu\|Takahashi, Shin\|Ishioka, Chikashi
PMID:	27435270

2272.
Journal:	Oncol Lett. 2016 Aug;12(2):1415-1421.
Title:	Prognostic role of KRAS mutations in Sardinian patients with colorectal carcinoma.
Author:	Palomba, Grazia\|Cossu, Antonio\|Paliogiannis, Panagiotis\|Pazzola, Antonio\|Baldino, Giovanni\|Scartozzi, Mario\|Ionta, Maria Teresa\|Ortu, Salvatore\|Capelli, Francesca\|Lanzillo, Annamaria\|Sedda, Tito\|Sanna, Giovanni\|Barca, Michela\|Virdis, Luciano\|Budroni, Mari
PMID:	27446446

2273.
Journal:	Oncotarget. 2016 Oct 11;7(41):66595-66605.
Title:	Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma.
Author:	Rachiglio, Anna Maria\|Esposito Abate, Riziero\|Sacco, Alessandra\|Pasquale, Raffaella\|Fenizia, Francesca\|Lambiase, Matilde\|Morabito, Alessandro\|Montanino, Agnese\|Rocco, Gaetano\|Romano, Carmen\|Nappi, Anna\|Iaffaioli, Rosario Vincenzo\|Tatangelo, Fabiana\|Botti,
PMID:	27448974

2274.
Journal:	Oncol Rep. 2016 Sep;36(3):1672-8.
Title:	GATA binding protein 2 overexpression is associated with poor prognosis in KRAS mutant colorectal cancer.
Author:	Xu, Kai\|Wang, Jiayuan\|Gao, Jing\|Di, Jiabo\|Jiang, Beihai\|Chen, Lei\|Wang, Zaozao\|Wang, Aidong\|Wu, Fan\|Wu, Wei\|Shen, Lin\|Su, Xiangqian
PMID:	27460045

2275.
Journal:	J Biomol Screen. 2016 Oct;21(9):989-97.
Title:	Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.
Author:	Severyn, Bryan\|Nguyen, Thi\|Altman, Michael D\|Li, Lixia\|Nagashima, Kumiko\|Naumov, George N\|Sathyanarayanan, Sriram\|Cook, Erica\|Morris, Erick\|Ferrer, Marc\|Arthur, Bill\|Benita, Yair\|Watters, Jim\|Loboda, Andrey\|Hermes, Jeff\|Gilliland, D Gary\|Cleary, Michelle
PMID:	27461835

2276.
Journal:	Cancer Med. 2016 Sep;5(9):2249-60.
Title:	Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance).
Author:	Hatch, Ace J\|Sibley, Alexander B\|Starr, Mark D\|Brady, J Chris\|Jiang, Chen\|Jia, Jingquan\|Bowers, Daniel L\|Pang, Herbert\|Owzar, Kouros\|Niedzwiecki, Donna\|Innocenti, Federico\|Venook, Alan P\|Hurwitz, Herbert I\|Nixon, Andrew B
PMID:	27465221

2277.
Journal:	Biomed Pharmacother. 2016 Aug;82:528-36.
Title:	IGF1R and c-met as therapeutic targets for colorectal cancer.
Author:	Shali, Hajar\|Ahmadi, Majid\|Kafil, Hossein Samadi\|Dorosti, Abbasali\|Yousefi, Mehdi
PMID:	27470393

2278.
Journal:	BMC Cancer. 2016 Aug 2;16:585.
Title:	A rational two-step approach to KRAS mutation testing in colorectal cancer using high resolution melting analysis and pyrosequencing.
Author:	Mack, Elisabeth\|Stabla, Kathleen\|Riera-Knorrenschild, Jorge\|Moll, Roland\|Neubauer, Andreas\|Brendel, Cornelia
PMID:	27485514

2279.
Journal:	J Pathol Clin Res. 2016 Apr 15;2(3):166-74.
Title:	Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations.
Author:	Crobach, Stijn\|Ruano, Dina\|van Eijk, Ronald\|Schrumpf, Melanie\|Fleuren, Gertjan\|van Wezel, Tom\|Morreau, Hans
PMID:	27499925

2280.
Journal:	Oncotarget. 2016 Sep 13;7(37):59441-59457.
Title:	TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer.
Author:	Tarpgaard, Line S\|Orum-Madsen, Maj Sofie\|Christensen, Ib J\|Nordgaard, Cathrine\|Noer, Julie\|Guren, Tormod K\|Glimelius, Bengt\|Sorbye, Halfdan\|Ikdahl, Tone\|Kure, Elin H\|Tveit, Kjell M\|Nielsen, Hans J\|Pfeiffer, Per\|Brunner, Nils\|Moreira, Jose M A
PMID:	27509063

2281.
Journal:	Surg Pathol Clin. 2016 Sep;9(3):427-39.
Title:	Molecular Evaluation of Colorectal Adenocarcinoma: Current Practice and Emerging Concepts.
Author:	Nowak, Jonathan A\|Hornick, Jason L
PMID:	27523970

2282.
Journal:	Oncotarget. 2016 Oct 11;7(41):66660-66678.
Title:	Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma.
Author:	Hu, Liang\|Wang, Ruo-Yu\|Cai, Jian\|Feng, Dan\|Yang, Guang-Zhen\|Xu, Qing-Guo\|Zhai, Yan-Xia\|Zhang, Yu\|Zhou, Wei-Ping\|Cai, Qing-Ping
PMID:	27556502

2283.
Journal:	BMC Cancer. 2016 Aug 25;16(1):683.
Title:	High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.
Author:	Padhan, Narendra\|Nordling, Torbjorn E M\|Sundstrom, Magnus\|Akerud, Peter\|Birgisson, Helgi\|Nygren, Peter\|Nelander, Sven\|Claesson-Welsh, Lena
PMID:	27562229

2284.
Journal:	Med Oncol. 2016 Oct;33(10):106.
Title:	Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Shokeen, Yogender\|Minhas, Sachin\|Aggarwal, Shyam
PMID:	27568332

2285.
Journal:	Cancer Lett. 2016 Nov 1;382(1):32-43.
Title:	Broad RTK-targeted therapy overcomes molecular heterogeneity-driven resistance to cetuximab via vectored immunoprophylaxis in colorectal cancer.
Author:	Hu, Shi\|Dai, Haibin\|Li, Tian\|Tang, Ying\|Fu, Wenyan\|Yuan, Qingning\|Wang, Feifei\|Lv, Gaojian\|Lv, Yuanyuan\|Fan, Xiaoyan\|Zhang, Sheng\|Jin, Ruobing\|Shen, Yafeng\|Lin, Fangxing\|Ye, Xuting\|Ding, Min\|Yang, Yongji\|Lei, Changhai
PMID:	27569653

2286.
Journal:	World J Gastroenterol. 2016 Aug 14;22(30):6944-54.
Title:	Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
Author:	Lo Nigro, Cristiana\|Ricci, Vincenzo\|Vivenza, Daniela\|Granetto, Cristina\|Fabozzi, Teresa\|Miraglio, Emanuela\|Merlano, Marco C
PMID:	27570430

2287.
Journal:	Expert Opin Emerg Drugs. 2016 Sep;21(3):267-82.
Title:	Emerging tyrosine kinase inhibitors for the treatment of metastatic colorectal cancer.
Author:	Matos, Ignacio\|Elez, Elena\|Capdevila, Jaume\|Tabernero, Josep
PMID:	27578253

2288.
Journal:	Onco Targets Ther. 2016 Aug 25;9:5257-70.
Title:	Correlations between EGFR gene polymorphisms and pleural metastasis of lung adenocarcinoma.
Author:	Guo, Haisheng\|Xing, Yunhui\|Mu, Ailan\|Li, Xia\|Li, Tingshan\|Bian, Xia\|Yang, Chunmei\|Zhang, Xiaolei\|Liu, Yuefen\|Wang, Xunguo
PMID:	27601918

2289.
Journal:	Oncol Lett. 2016 Sep;12(3):1868-1876.
Title:	Cetuximab intensifies the ADCC activity of adoptive NK cells in a nude mouse colorectal cancer xenograft model.
Author:	Chen, Shanshan\|Li, Xuechun\|Chen, Rongming\|Yin, Mingang\|Zheng, Qiuhong
PMID:	27602116

2290.
Journal:	Exp Lung Res. 2016 Sep;42(7):346-353.
Title:	Targeting H19 by lentivirus-mediated RNA interference increases A549 cell migration and invasion.
Author:	Wang, Lin\|Sun, Yan\|Yi, Jiqun\|Wang, Xiuwen\|Liang, Jizhen\|Pan, Zhaojun\|Li, Li\|Jiang, Gaofeng
PMID:	27607135

2291.
Journal:	Gastroenterol Res Pract. 2016;2016:3481578.
Title:	Prognostic Impact of mRNA Expression Levels of HER1-4 (ERBB1-4) in Patients with Locally Advanced Rectal Cancer.
Author:	Kripp, Melanie\|Merx, Kirsten\|Wirtz, Ralph Markus\|Gaiser, Timo\|Eidt, Sebastian\|Schwaab, Juliana\|Post, Stefan\|Wenz, Frederik\|Hochhaus, Andreas\|Hofheinz, Ralf-Dieter\|Erben, Philipp
PMID:	27610130

2292.
Journal:	World J Gastroenterol. 2016 Aug 28;22(32):7215-25.
Title:	Multisciplinary management of patients with liver metastasis from colorectal cancer.
Author:	De Greef, Kathleen\|Rolfo, Christian\|Russo, Antonio\|Chapelle, Thiery\|Bronte, Giuseppe\|Passiglia, Francesco\|Coelho, Andreia\|Papadimitriou, Konstantinos\|Peeters, Marc
PMID:	27621569

2293.
Journal:	Oncotarget. 2016 Oct 18;7(42):68749-68767.
Title:	Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer.
Author:	Moench, Romana\|Grimmig, Tanja\|Kannen, Vinicius\|Tripathi, Sudipta\|Faber, Marc\|Moll, Eva-Maria\|Chandraker, Anil\|Lissner, Reinhard\|Germer, Christoph-Thomas\|Waaga-Gasser, Ana Maria\|Gasser, Martin
PMID:	27626684

2294.
Journal:	Anticancer Res. 2016 Sep;36(9):4421-6.
Title:	The Role of Cetuximab in the Induction of Anticancer Immune Response in Colorectal Cancer Treatment.
Author:	Holubec, Lubos\|Polivka, Jiri Jr\|Safanda, Martin\|Karas, Michal\|Liska, Vaclav
PMID:	27630277

2295.
Journal:	PLoS One. 2016 Sep 15;11(9):e0163070.
Title:	Optimized Multiplex Detection of 7 KRAS Mutations by Taqman Allele-Specific qPCR.
Author:	Orue, Andrea\|Rieber, Manuel
PMID:	27632281

2296.
Journal:	Asian Pac J Cancer Prev. 2016;17(8):4019-23.
Title:	Plant Phenolics Ferulic Acid and P-Coumaric Acid Inhibit Colorectal Cancer Cell Proliferation through EGFR Down-Regulation.
Author:	Roy, Nabarun\|Narayanankutty, Arunaksharan\|Nazeem, P A\|Valsalan, Ravisankar\|Babu, T D\|Mathew, Deepu
PMID:	27644655

2297.
Journal:	Am J Cancer Res. 2016 Aug 1;6(8):1609-23. eCollection 2016.
Title:	A perspective on anti-EGFR therapies targeting triple-negative breast cancer.
Author:	Nakai, Katsuya\|Hung, Mien-Chie\|Yamaguchi, Hirohito
PMID:	27648353

2298.
Journal:	Acc Chem Res. 2016 Oct 18;49(10):2099-2106.
Title:	Identifying N-Glycan Biomarkers in Colorectal Cancer by Mass Spectrometry.
Author:	Sethi, Manveen K\|Hancock, William S\|Fanayan, Susan
PMID:	27653471

2299.
Journal:	Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title:	Genomic characterization of liver metastases from colorectal cancer patients.
Author:	Sayagues, Jose Maria\|Corchete, Luis Antonio\|Gutierrez, Maria Laura\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria\|Bengoechea, Oscar\|Ferminan, Encarna\|Anduaga, Maria Fernanda\|Del Carmen, Sofia\|Iglesias, Manuel\|Esteban, Carmen\|Angoso, Maria\|Alcazar, Jose Ant
PMID:	27662660

2300.
Journal:	World J Gastrointest Oncol. 2016 Sep 15;8(9):642-55.
Title:	Role of targeted therapy in metastatic colorectal cancer.
Author:	Ohhara, Yoshihito\|Fukuda, Naoki\|Takeuchi, Satoshi\|Honma, Rio\|Shimizu, Yasushi\|Kinoshita, Ichiro\|Dosaka-Akita, Hirotoshi
PMID:	27672422

2301.
Journal:	Oncologist. 2016 Nov;21(11):1306-1314.
Title:	Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer.
Author:	Rankin, Andrew\|Klempner, Samuel J\|Erlich, Rachel\|Sun, James X\|Grothey, Axel\|Fakih, Marwan\|George, Thomas J Jr\|Lee, Jeeyun\|Ross, Jeffrey S\|Stephens, Philip J\|Miller, Vincent A\|Ali, Siraj M\|Schrock, Alexa B
PMID:	27682134

2302.
Journal:	PLoS One. 2016 Sep 29;11(9):e0163444.
Title:	Multi-Center Evaluation of the Fully Automated PCR-Based Idylla KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer.
Author:	Solassol, Jerome\|Vendrell, Julie\|Markl, Bruno\|Haas, Christian\|Bellosillo, Beatriz\|Montagut, Clara\|Smith, Matthew\|O'Sullivan, Brendan\|D'Haene, Nicky\|Le Mercier, Marie\|Grauslund, Morten\|Melchior, Linea Cecilie\|Burt, Emma\|Cotter, Finbarr\|Stieber, Daniel\|Schm
PMID:	27685259

2303.
Journal:	Br J Cancer. 2016 Nov 8;115(10):1223-1233.
Title:	FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.
Author:	Marzi, L\|Combes, E\|Vie, N\|Ayrolles-Torro, A\|Tosi, D\|Desigaud, D\|Perez-Gracia, E\|Larbouret, C\|Montagut, C\|Iglesias, M\|Jarlier, M\|Denis, V\|Linares, L K\|Lam, E W-F\|Martineau, P\|Del Rio, M\|Gongora, C
PMID:	27685445

2304.
Journal:	J BUON. 2016 Jul-Aug;21(4):867-873.
Title:	Cbl-b regulates the sensitivity of cetuximab through ubiquitin-proteasome system in human gastric cancer cells.
Author:	Yu, Ping\|Fan, Yibo\|Qu, Xiujuan\|Zhang, Jingdong\|Song, Na\|Liu, Jing\|Liu, Yunpeng
PMID:	27685907

2305.
Journal:	J Pharm Health Care Sci. 2016 Sep 22;2:23.
Title:	Correlation between blood magnesium and calcium concentration in patients treated with an anti-EGFR antibody.
Author:	Tsujii, Toshiyasu\|Ogaki, Takafumi\|Nakae, Kaori\|Imai, Kiyotaka\|Kise, Daisuke\|Tada, Shoji\|Ueda, Hiroki\|Moriyama, Masahiro
PMID:	27688901

2306.
Journal:	Biomed Res Int. 2016;2016:9850690.
Title:	Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective.
Author:	Chen, Guoli\|Yang, Zhaohai\|Eshleman, James R\|Netto, George J\|Lin, Ming-Tseh
PMID:	27699178

2307.
Journal:	Oncotarget. 2016 Nov 8;7(45):73402-73413.
Title:	Asporin enhances colorectal cancer metastasis through activating the EGFR/src/cortactin signaling pathway.
Author:	Wu, Huo\|Jing, Xiaoqian\|Cheng, Xi\|He, Yonggang\|Hu, Lei\|Wu, Haoxuan\|Ye, Feng\|Zhao, Ren
PMID:	27705916

2308.
Journal:	Oncotarget. 2016 Nov 1;7(44):72167-72183.
Title:	A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors.
Author:	Gelfo, Valerio\|Rodia, Maria Teresa\|Pucci, Michela\|Dall'Ora, Massimiliano\|Santi, Spartaco\|Solmi, Rossella\|Roth, Lee\|Lindzen, Moshit\|Bonafe, Massimiliano\|Bertotti, Andrea\|Caramelli, Elisabetta\|Lollini, Pier-Luigi\|Trusolino, Livio\|Yarden, Yosef\|D'Uva, Gabrie
PMID:	27708224

2309.
Journal:	Front Cell Dev Biol. 2016 Sep 21;4:103.
Title:	Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer.
Author:	Burke, Lorraine\|Butler, Clare T\|Murphy, Adrian\|Moran, Bruce\|Gallagher, William M\|O'Sullivan, Jacintha\|Kennedy, Breandan N
PMID:	27709113

2310.
Journal:	J Clin Invest. 2016 Nov 1;126(11):4157-4173.
Title:	Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer.
Author:	Yin, Mingzhu\|Li, Xia\|Tan, Shu\|Zhou, Huanjiao Jenny\|Ji, Weidong\|Bellone, Stefania\|Xu, Xiaocao\|Zhang, Haifeng\|Santin, Alessandro D\|Lou, Ge\|Min, Wang
PMID:	27721235

2311.
Journal:	BMC Cancer. 2016 Oct 12;16(1):791.
Title:	Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model.
Author:	Ding, Chenbo\|Li, Longmei\|Yang, Taoyu\|Fan, Xiaobo\|Wu, Guoqiu
PMID:	27729020

2312.
Journal:	Minerva Chir. 2016 Dec;71(6):382-397. Epub 2016 Oct 12.
Title:	Unresectable liver metastases in colorectal cancer: review of current strategies.
Author:	Sueur, Benjamin\|Pellerin, Olivier\|Voron, Thibault\|Pointet, Anne L\|Taieb, Julien\|Pernot, Simon
PMID:	27733753

2313.
Journal:	J Transl Med. 2016 Oct 13;14(1):292.
Title:	Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study.
Author:	Palomba, Grazia\|Doneddu, Valentina\|Cossu, Antonio\|Paliogiannis, Panagiotis\|Manca, Antonella\|Casula, Milena\|Colombino, Maria\|Lanzillo, Annamaria\|Defraia, Efisio\|Pazzola, Antonio\|Sanna, Giovanni\|Putzu, Carlo\|Ortu, Salvatore\|Scartozzi, Mario\|Ionta, Maria Ter
PMID:	27737711

2314.
Journal:	Expert Opin Biol Ther. 2016 Dec;16(12):1549-1555.
Title:	The prospect of patritumab for treating non-small cell lung cancer.
Author:	Horinouchi, Hidehito
PMID:	27744717

2315.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):687-704.
Title:	RAS and BRAF in metastatic colorectal cancer management.
Author:	Gong, Jun\|Cho, May\|Fakih, Marwan
PMID:	27747083

2316.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):705-712.
Title:	Beyond RAS and BRAF: a target rich disease that is ripe for picking.
Author:	Friedrich, Tyler\|Leong, Stephen\|Lieu, Christopher H
PMID:	27747084

2317.
Journal:	BMC Med Genomics. 2016 Oct 19;9(1):65.
Title:	Adaptation of a RAS pathway activation signature from FF to FFPE tissues in colorectal cancer.
Author:	Omolo, Bernard\|Yang, Mingli\|Lo, Fang Yin\|Schell, Michael J\|Austin, Sharon\|Howard, Kellie\|Madan, Anup\|Yeatman, Timothy J
PMID:	27756306

2318.
Journal:	Mol Cancer. 2016 Oct 18;15(1):63.
Title:	Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author:	Kovaleva, Valentina\|Geissler, Anna-Lena\|Lutz, Lisa\|Fritsch, Ralph\|Makowiec, Frank\|Wiesemann, Sebastian\|Hopt, Ulrich T\|Passlick, Bernward\|Werner, Martin\|Lassmann, Silke
PMID:	27756406

2319.
Journal:	Cancer Discov. 2016 Dec;6(12):OF6.
Title:	Triple Therapy Improves Colorectal Cancer Response.
Author:
PMID:	27770002

2320.
Journal:	World J Clin Oncol. 2016 Oct 10;7(5):340-351.
Title:	Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer.
Author:	Sobani, Zain A\|Sawant, Ashwin\|Jafri, Mikram\|Correa, Amit Keith\|Sahin, Ibrahim Halil
PMID:	27777877

2321.
Journal:	Pathologe. 2016 Nov;37(Suppl 2):191-195.
Title:	[Pancreatic acinar neoplasms : Comparative molecular characterization].
Author:	Bergmann, F
PMID:	27807633

2322.
Journal:	Oncotarget. 2016 Dec 6;7(49):80888-80900.
Title:	FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc.
Author:	Yu, Yiyi\|Guo, Mengzhou\|Wei, Ye\|Yu, Shan\|Li, Hong\|Wang, Yan\|Xu, Xiaojing\|Cui, Yuehong\|Tian, Jiawen\|Liang, Li\|Peng, Ke\|Liu, Tianshu
PMID:	27825133

2323.
Journal:	Sci Rep. 2016 Nov 10;6:37062.
Title:	Noscapine targets EGFR(p-Tyr1068) to suppress the proliferation and invasion of MG63 cells.
Author:	He, Ming\|Jiang, Linlin\|Ren, Zhaozhou\|Wang, Guangbin\|Wang, Jiashi
PMID:	27830833

2324.
Journal:	Oncotarget. 2016 Dec 6;7(49):81402-81409.
Title:	Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy.
Author:	Feng, Ye\|Gao, Shuohui\|Gao, Yongjian\|Wang, Xuefeng\|Chen, Zhi
PMID:	27833077

2325.
Journal:	J BUON. 2016 Sept-Oct;21(5):1287-1295.
Title:	Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Author:	Cavic, Milena\|Krivokuca, Ana\|Boljevic, Ivana\|Brotto, Ksenija\|Jovanovic, Katarina\|Tanic, Miljana\|Filipovic, Lana\|Zec, Manja\|Malisic, Emina\|Jankovic, Radmila\|Radulovic, Sinisa
PMID:	27837635

2326.
Journal:	Cell Physiol Biochem. 2016;40(1-2):62-76.
Title:	MicroRNAs as Regulators, Biomarkers and Therapeutic Targets in the Drug Resistance of Colorectal Cancer.
Author:	Xie, Tao\|Huang, Mengxi\|Wang, Ye\|Wang, Liya\|Chen, Cheng\|Chu, Xiaoyuan
PMID:	27842308

2327.
Journal:	ESMO Open. 2016 Aug 4;1(4):e000079.
Title:	Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer.
Author:	Sartore-Bianchi, Andrea\|Valtorta, Emanuele\|Amatu, Alessio\|Veronese, Silvio\|Lauricella, Calogero\|Bonazzina, Erica\|Siravegna, Giulia\|Truini, Mauro\|Bardelli, Alberto\|Siena, Salvatore
PMID:	27843629

2328.
Journal:	ESMO Open. 2016 Sep 16;1(5):e000088.
Title:	Therapeutic value of EGFR inhibition in CRC and NSCLC: 15 years of clinical evidence.
Author:	Troiani, Teresa\|Napolitano, Stefania\|Della Corte, Carminia Maria\|Martini, Giulia\|Martinelli, Erika\|Morgillo, Floriana\|Ciardiello, Fortunato
PMID:	27843640

2329.
Journal:	Sci Rep. 2016 Nov 15;6:37240.
Title:	A comparative analysis and guidance for individualized chemotherapy of stage II and III colorectal cancer patients based on pathological markers.
Author:	Han, Yang\|Lu, Su\|Yu, Fudong\|Liu, Xisheng\|Sun, Huimin\|Wang, Jingtao\|Zhu, Xingwu\|Lu, Huijun\|Yue, Hao\|Wang, Jing\|Lin, Jun\|Zhou, Chongzhi\|Tang, Huamei\|Peng, Zhihai
PMID:	27845412

2330.
Journal:	Elife. 2016 Nov 15;5.
Title:	Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.
Author:	Verissimo, Carla S\|Overmeer, Rene M\|Ponsioen, Bas\|Drost, Jarno\|Mertens, Sander\|Verlaan-Klink, Ingrid\|Gerwen, Bastiaan van\|van der Ven, Marieke\|Wetering, Marc van de\|Egan, David A\|Bernards, Rene\|Clevers, Hans\|Bos, Johannes L\|Snippert, Hugo J
PMID:	27845624

2331.
Journal:	Eur Rev Med Pharmacol Sci. 2016 Nov;20(21):4474-4481.
Title:	Nox1 promotes colon cancer cell metastasis via activation of the ADAM17 pathway.
Author:	Wang, H-P\|Wang, X\|Gong, L-F\|Chen, W-J\|Hao, Z\|Feng, S-W\|Wu, Y-B\|Ye, T\|Cai, Y-K
PMID:	27874952

2332.
Journal:	Oncol Res Treat. 2016;39(12):796-802.
Title:	Targeted Therapy of Colorectal Cancer.
Author:	Seeber, Andreas\|Gastl, Gunther
PMID:	27889786

2333.
Journal:	Curr Mol Med. 2016;16(9):829-839.
Title:	Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features.
Author:	Lee, H S\|Park, K U\|Kim, D-W\|Lhn, M H\|Kim, W H\|Seo, A N\|Chang, H E\|Nam, S K\|Lee, S Y\|Oh, H-K\|Kang, S-B
PMID:	27889996

2334.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(11):1361-1365.
Title:	[New Classification for Advanced Colorectal Cancer Using CancerPlex(R)Genomic Tests].
Author:	Kameyama, Hitoshi\|Shimada, Yoshifumi\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Okuda, Shujiro\|Ling, Yiwei\|Izutsu, Hiroshi\|Kodama, Keisuke\|Nakada, Mitsutaka\|Wakai, Toshifumi
PMID:	27899776

2335.
Journal:	Stem Cell Res Ther. 2016 Dec 1;7(1):181.
Title:	Bile acid: a potential inducer of colon cancer stem cells.
Author:	Farhana, Lulu\|Nangia-Makker, Pratima\|Arbit, Evan\|Shango, Kathren\|Sarkar, Sarah\|Mahmud, Hamidah\|Hadden, Timothy\|Yu, Yingjie\|Majumdar, Adhip P N
PMID:	27908290

2336.
Journal:	Int J Mol Sci. 2016 Dec 1;17(12). pii: ijms17122015.
Title:	High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer.
Author:	Jeantet, Marion\|Tougeron, David\|Tachon, Gaelle\|Cortes, Ulrich\|Archambaut, Celine\|Fromont, Gaelle\|Karayan-Tapon, Lucie
PMID:	27916952

2337.
Journal:	World J Radiol. 2016 Nov 28;8(11):880-886.
Title:	Mechanisms underlying (18)F-fluorodeoxyglucose accumulation in colorectal cancer.
Author:	Kawada, Kenji\|Iwamoto, Masayoshi\|Sakai, Yoshiharu
PMID:	27928469

2338.
Journal:	Nat Commun. 2016 Dec 8;7:13665.
Title:	Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer.
Author:	Van Emburgh, Beth O\|Arena, Sabrina\|Siravegna, Giulia\|Lazzari, Luca\|Crisafulli, Giovanni\|Corti, Giorgio\|Mussolin, Benedetta\|Baldi, Federica\|Buscarino, Michela\|Bartolini, Alice\|Valtorta, Emanuele\|Vidal, Joana\|Bellosillo, Beatriz\|Germano, Giovanni\|Pietranton
PMID:	27929064

2339.
Journal:	Liver Cancer. 2016 Nov;6(1):72-79.
Title:	Recent Advances in Chemotherapy and Surgery for Colorectal Liver Metastases.
Author:	Passot, Guillaume\|Soubrane, Olivier\|Giuliante, Felice\|Zimmitti, Giuseppe\|Goere, Diane\|Yamashita, Suguru\|Vauthey, Jean-Nicolas
PMID:	27995091

2340.
Journal:	Int J Mol Sci. 2016 Dec 16;17(12). pii: ijms17122117.
Title:	Clinical Application of Targeted Next Generation Sequencing for Colorectal Cancers.
Author:	Fontanges, Quitterie\|De Mendonca, Ricardo\|Salmon, Isabelle\|Le Mercier, Marie\|D'Haene, Nicky
PMID:	27999270

2341.
Journal:	Korean J Gastroenterol. 2016 Dec 25;68(6):303-311.
Title:	[Target Therapy in Unresectable or Metastatic Colorectal Cancer].
Author:	Kim, Jae Hyun\|Park, Seun Ja
PMID:	28025473

2342.
Journal:	Adv Clin Exp Med. 2016 Nov-Dec;25(6):1273-1279.
Title:	Monitoring of Circulating Tumor Cells by a Combination of Immunomagnetic Enrichment and RT-PCR in Colorectal Cancer Patients Undergoing Surgery.
Author:	Vojtechova, Gabriela\|Benesova, Lucie\|Belsanova, Barbora\|Minarikova, Petra\|Levy, Miroslav\|Lipska, Ludmila\|Suchanek, Stepan\|Zavoral, Miroslav\|Minarik, Marek
PMID:	28028983

2343.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):1800-1802.
Title:	[A Case of Metastatic Colon Cancer Dramatically Affected by Anti-EGFR Antibody Therapy].
Author:	Yagi, Ryoma\|Shimada, Yoshifumi\|Miura, Kohei\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Kobayashi, Takashi\|Kameyama, Hitoshi\|Wakai, Toshifumi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa
PMID:	28133136

2344.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):2307-2309.
Title:	[A Case of Metastatic Colorectal Cancer with HER2 Overexpression/Amplification].
Author:	Matsumoto, Akio\|Shimada, Yoshifumi\|Yagi, Ryoma\|Miura, Kohei\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Kameyama, Hitoshi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Ichikawa, Hiroshi\|Sakata, Jun\|Kobayashi, Takashi\|Wakai, Toshifumi
PMID:	28133304

2345.
Journal:	Acta Med Litu. 2016;23(1):24-34.
Title:	Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience.
Author:	Baltruskeviciene, Edita\|Mickys, Ugnius\|Zvirblis, Tadas\|Stulpinas, Rokas\|Pipiriene Zelviene, Terese\|Aleknavicius, Eduardas
PMID:	28356789

2346.
Journal:	Oncotarget. 2017 Apr 4;8(14):22414-22432.
Title:	Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer.
Author:	Zou, Zheng-Zhi\|Nie, Pei-Pei\|Li, Ya-Wei\|Hou, Ben-Xin\|Rui-Li\|Shi, Xin-Peng\|Ma, Zhao-Kui\|Han, Bao-Wei\|Luo, Xiao-Yong
PMID:	26461472

2347.
Journal:	Oncotarget. 2017 Feb 21;8(8):13611-13619.
Title:	Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA.
Author:	Del Re, Marzia\|Tiseo, Marcello\|Bordi, Paola\|D'Incecco, Armida\|Camerini, Andrea\|Petrini, Iacopo\|Lucchesi, Maurizio\|Inno, Alessandro\|Spada, Daniele\|Vasile, Enrico\|Citi, Valentina\|Malpeli, Giorgio\|Testa, Enrica\|Gori, Stefania\|Falcone, Alfredo\|Amoroso, Domeni
PMID:	26799287

2348.
Journal:	Mol Carcinog. 2017 Jan;56(1):106-117.
Title:	Significance of FGF9 gene in resistance to anti-EGFR therapies targeting colorectal cancer: A subset of colorectal cancer patients with FGF9 upregulation may be resistant to anti-EGFR therapies.
Author:	Mizukami, Takuro\|Togashi, Yosuke\|Naruki, Saeko\|Banno, Eri\|Terashima, Masato\|de Velasco, Marco A\|Sakai, Kazuko\|Yoneshige, Azusa\|Hayashi, Hidetoshi\|Fujita, Yoshihiko\|Tomida, Shuta\|Nakajima, Takako Eguchi\|Fujino, Takashi\|Boku, Narikazu\|Ito, Akihiko\|Nakagawa,
PMID:	26916220

2349.
Journal:	Environ Toxicol. 2017 Feb;32(2):669-678.
Title:	Inhibition of NF-kappaB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38.
Author:	Chen, Ming-Cheng\|Lee, Nien-Hung\|Hsu, Hsi-Hsien\|Ho, Tsung-Jung\|Tu, Chuan-Chou\|Chen, Ray-Jade\|Lin, Yueh-Min\|Viswanadha, Vijaya Padma\|Kuo, Wei-Wen\|Huang, Chih-Yang
PMID:	27060453

2350.
Journal:	Clin Cancer Res. 2017 Jan 1;23(1):104-115.
Title:	BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression.
Author:	Barras, David\|Missiaglia, Edoardo\|Wirapati, Pratyaksha\|Sieber, Oliver M\|Jorissen, Robert N\|Love, Chris\|Molloy, Peter L\|Jones, Ian T\|McLaughlin, Stephen\|Gibbs, Peter\|Guinney, Justin\|Simon, Iris M\|Roth, Arnaud D\|Bosman, Fred T\|Tejpar, Sabine\|Delorenzi, Maur
PMID:	27354468

2351.
Journal:	Clin Cancer Res. 2017 Jan 1;23(1):159-170.
Title:	Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer.
Author:	De Robertis, Mariangela\|Loiacono, Luisa\|Fusilli, Caterina\|Poeta, Maria Luana\|Mazza, Tommaso\|Sanchez, Massimo\|Marchionni, Luigi\|Signori, Emanuela\|Lamorte, Giuseppe\|Vescovi, Angelo Luigi\|Garcia-Foncillas, Jesus\|Fazio, Vito Michele
PMID:	27401248

2352.
Journal:	Clin Cancer Res. 2017 Jan 15;23(2):549-561.
Title:	ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer.
Author:	Mustafi, Reba\|Dougherty, Urszula\|Mustafi, Devkumar\|Ayaloglu-Butun, Fatma\|Fletcher, Michelle\|Adhikari, Sarbani\|Sadiq, Farhana\|Meckel, Katherine\|Haider, Haider I\|Khalil, Abdurahman\|Pekow, Joel\|Konda, Vani\|Joseph, Loren\|Hart, John\|Fichera, Alessandro\|Li, Yan
PMID:	27489286

2353.
Journal:	Abdom Radiol (NY). 2017 Feb;42(2):451-459.
Title:	Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90.
Author:	Magnetta, Michael J\|Ghodadra, Anish\|Lahti, Steven J\|Xing, Minzhi\|Zhang, Di\|Kim, Hyun S
PMID:	27600383

2354.
Journal:	Anticancer Drugs. 2017 Jan;28(1):66-74.
Title:	Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway.
Author:	Guo, Xiaoqing\|Meng, Yue\|Sheng, Xiaotong\|Guan, Yuan\|Zhang, Fenglei\|Han, Zhen\|Kang, Yuying\|Tai, Guihua\|Zhou, Yifa\|Cheng, Hairong
PMID:	27603596

2355.
Journal:	Mol Carcinog. 2017 Mar;56(3):1068-1081.
Title:	KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation.
Author:	Sun, Eun Gene\|Lee, Kyung Hwa\|Ko, Yoo-Seung\|Choi, Hui Jeong\|Yang, Jung-In\|Lee, Jae Hyuk\|Chung, Ik Joo\|Paek, Yun-Woong\|Kim, Hangun\|Bae, Jeong A\|Kim, Kyung Keun
PMID:	27648936

2356.
Journal:	Genes Chromosomes Cancer. 2017 Mar;56(3):214-220.
Title:	Synonymous EGFR variant p.Q787Q is neither prognostic nor predictive in patients with lung adenocarcinoma.
Author:	Leichsenring, Jonas\|Volckmar, Anna-Lena\|Magios, Nikolaus\|Morais de Oliveira, Cristiano Manuel\|Penzel, Roland\|Brandt, Regine\|Kirchner, Martina\|Bozorgmehr, Farastuk\|Thomas, Michael\|Schirmacher, Peter\|Warth, Arne\|Endris, Volker\|Stenzinger, Albrecht
PMID:	27750395

2357.
Journal:	J Natl Cancer Inst. 2016 Oct 22;109(2). pii: djw209.
Title:	Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
Author:	Picco, Gabriele\|Petti, Consalvo\|Sassi, Francesco\|Grillone, Katia\|Migliardi, Giorgia\|Rossi, Teresa\|Isella, Claudio\|Di Nicolantonio, Federica\|Sarotto, Ivana\|Sapino, Anna\|Bardelli, Alberto\|Trusolino, Livio\|Bertotti, Andrea\|Medico, Enzo
PMID:	27771609

2358.
Journal:	Invest New Drugs. 2017 Feb;35(1):68-78.
Title:	A phase 1 study combining the HER3 antibody seribantumab (MM-121) and cetuximab with and without irinotecan.
Author:	Cleary, James M\|McRee, Autumn J\|Shapiro, Geoffrey I\|Tolaney, Sara M\|O'Neil, Bert H\|Kearns, Jeffrey D\|Mathews, Sara\|Nering, Rachel\|MacBeath, Gavin\|Czibere, Akos\|Sharma, Sunil\|Korn, W Michael
PMID:	27853996

2359.
Journal:	Oncol Rep. 2017 Jan;37(1):123-130.
Title:	miR-20b reduces 5-FU resistance by suppressing the ADAM9/EGFR signaling pathway in colon cancer.
Author:	Fu, Qiang\|Cheng, Jing\|Zhang, Jindai\|Zhang, Yonglei\|Chen, Xiaobing\|Luo, Suxia\|Xie, Jianguo
PMID:	27878272

2360.
Journal:	Int J Cancer. 2017 Feb 15;140(4):922-929.
Title:	EGFR gene copy number predicts response to anti-EGFR treatment in RAS wild type and RAS/BRAF/PIK3CA wild type metastatic colorectal cancer.
Author:	Algars, Annika\|Sundstrom, Jari\|Lintunen, Minnamaija\|Jokilehto, Terhi\|Kytola, Soili\|Kaare, Milja\|Vainionpaa, Reetta\|Orpana, Arto\|Osterlund, Pia\|Ristimaki, Ari\|Carpen, Olli\|Ristamaki, Raija
PMID:	27879995

2361.
Journal:	Oncotarget. 2017 Jan 3;8(1):954-966.
Title:	Hierarchical investigating the predictive value of p53, COX2, EGFR, nm23 in the post-operative patients with colorectal carcinoma.
Author:	Du, Peng\|Xu, Bin\|Zhang, Dachuan\|Shao, Yingjie\|Zheng, Xiao\|Li, Xiaodong\|Xiong, Yuqi\|Wu, Changping\|Jiang, Jingting
PMID:	27888614

2362.
Journal:	Biomed Pharmacother. 2017 Jan;85:389-398.
Title:	In-silico and in-vitro anti-cancer potential of a curcumin analogue (1E, 6E)-1, 7-di (1H-indol-3-yl) hepta-1, 6-diene-3, 5-dione.
Author:	Sufi, Shamim Akhtar\|Adigopula, Lakshmi Narayana\|Syed, Safiulla Basha\|Mukherjee, Victor\|Coumar, Mohane S\|Rao, H Surya Prakash\|Rajagopalan, Rukkumani
PMID:	27889234

2363.
Journal:	Pharmacogenomics J. 2017 Dec;17(6):535-542.
Title:	Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis.
Author:	Morgen, E K\|Lenz, H-J\|Jonker, D J\|Tu, D\|Milano, G\|Graziano, F\|Zalcberg, J\|Karapetis, C S\|Dobrovic, A\|O'Callaghan, C J\|Liu, G
PMID:	27897268

2364.
Journal:	Oncotarget. 2017 Jan 3;8(1):1541-1554.
Title:	Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway.
Author:	Zhang, Xiaojian\|Liu, Kun\|Zhang, Tao\|Wang, Zhenlei\|Qin, Xuan\|Jing, Xiaoqian\|Wu, Haoxuan\|Ji, Xiaopin\|He, Yonggang\|Zhao, Ren
PMID:	27903975

2365.
Journal:	Eur J Cancer. 2017 Jan;70:87-98.
Title:	The relevance of primary tumour location in patients with metastatic colorectal cancer: A meta-analysis of first-line clinical trials.
Author:	Holch, Julian Walter\|Ricard, Ingrid\|Stintzing, Sebastian\|Modest, Dominik Paul\|Heinemann, Volker
PMID:	27907852

2366.
Journal:	Nat Rev Clin Oncol. 2017 Apr;14(4):235-246.
Title:	From tumour heterogeneity to advances in precision treatment of colorectal cancer.
Author:	Punt, Cornelis J A\|Koopman, Miriam\|Vermeulen, Louis
PMID:	27922044

2367.
Journal:	Oncotarget. 2017 Jan 17;8(3):5048-5056.
Title:	FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway.
Author:	Li, Kun\|Guo, Qunfeng\|Yang, Jun\|Chen, Hui\|Hu, Kewen\|Zhao, Juan\|Zheng, Shunxin\|Pang, Xiufeng\|Zhou, Sufang\|Dang, Yongyan\|Li, Lei
PMID:	27926503

2368.
Journal:	Int J Oncol. 2017 Jan;50(1):85-92.
Title:	Pro-metastatic intracellular signaling of the elaidic trans fatty acid.
Author:	Fujii, Kiyomu\|Luo, Yi\|Fujiwara-Tani, Rina\|Kishi, Shingo\|He, Song\|Yang, Shuyun\|Sasaki, Takamitsu\|Ohmori, Hitoshi\|Kuniyasu, Hiroki
PMID:	27959384

2369.
Journal:	Oncotarget. 2017 Jan 10;8(2):3206-3225.
Title:	KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies.
Author:	Wen, Qing\|Dunne, Philip D\|O'Reilly, Paul G\|Li, Gerald\|Bjourson, Anthony J\|McArt, Darragh G\|Hamilton, Peter W\|Zhang, Shu-Dong
PMID:	27965461

2370.
Journal:	Oncol Rep. 2017 Feb;37(2):785-792.
Title:	High concordance rate of KRAS/BRAF mutations and MSI-H between primary colorectal cancer and corresponding metastases.
Author:	Fujiyoshi, Kenji\|Yamamoto, Gou\|Takahashi, Akemi\|Arai, Yoshiko\|Yamada, Mina\|Kakuta, Miho\|Yamaguchi, Kensei\|Akagi, Yoshito\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Akagi, Kiwamu
PMID:	28000889

2371.
Journal:	Oncotarget. 2017 Jan 17;8(3):3980-4000.
Title:	Mechanisms of resistance to anti-EGFR therapy in colorectal cancer.
Author:	Zhao, Ben\|Wang, Lu\|Qiu, Hong\|Zhang, Mingsheng\|Sun, Li\|Peng, Ping\|Yu, Qianqian\|Yuan, Xianglin
PMID:	28002810

2372.
Journal:	Clin Transl Oncol. 2017 Jun;19(6):718-726.
Title:	High early growth response 1 (EGR1) expression correlates with resistance to anti-EGFR treatment in vitro and with poorer outcome in metastatic colorectal cancer patients treated with cetuximab.
Author:	Kumar, S S\|Tomita, Y\|Wrin, J\|Bruhn, M\|Swalling, A\|Mohammed, M\|Price, T J\|Hardingham, J E
PMID:	28005260

2373.
Journal:	Int J Cancer. 2017 Apr 1;140(7):1653-1661.
Title:	Copy number variations in DCC/18q and ERBB2/17q are associated with disease-free survival in microsatellite stable colon cancer.
Author:	Sefrioui, David\|Vermeulin, Thomas\|Blanchard, France\|Chapusot, Caroline\|Beaussire, Ludivine\|Armengol-Debeir, Laura\|Sesboue, Richard\|Gangloff, Alice\|Hebbar, Mohamed\|Copin, Marie-Christine\|Houivet, Estelle\|Schwarz, Lilian\|Clatot, Florian\|Tuech, Jean-Jacques\|
PMID:	28006840

2374.
Journal:	Biochem J. 2017 Feb 20;474(5):647-665.
Title:	Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.
Author:	Said, Anan H\|Hu, Shien\|Abutaleb, Ameer\|Watkins, Tonya\|Cheng, Kunrong\|Chahdi, Ahmed\|Kuppusamy, Panjamurthy\|Saxena, Neeraj\|Xie, Guofeng\|Raufman, Jean-Pierre
PMID:	28008134

2375.
Journal:	Pathol Oncol Res. 2017 Jul;23(3):673-677.
Title:	EGFR Gene Amplification and KRAS Mutation Predict Response to Combination Targeted Therapy in Metastatic Colorectal Cancer.
Author:	Khan, Sajid A\|Zeng, Zhaoshi\|Shia, Jinru\|Paty, Philip B
PMID:	28025786

2376.
Journal:	Ann Oncol. 2017 Apr 1;28(4):824-830.
Title:	Adjuvant FOLFOX +/- cetuximab in full RAS and BRAF wildtype stage III colon cancer patients.
Author:	Taieb, J\|Balogoun, R\|Le Malicot, K\|Tabernero, J\|Mini, E\|Folprecht, G\|Van Laethem, J-L\|Emile, J-F\|Mulot, C\|Fratte, S\|Levache, C-B\|Saban-Roche, L\|Thaler, J\|Petersen, L N\|Bridgewater, J\|Perkins, G\|Lepage, C\|Van Cutsem, E\|Zaanan, A\|Laurent-Puig, P
PMID:	28031175

2377.
Journal:	Oncotarget. 2017 Jan 17;8(3):4277-4288.
Title:	Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Author:	Bosch-Vilaro, Albert\|Jacobs, Bart\|Pomella, Valentina\|Abbasi Asbagh, Layka\|Kirkland, Richard\|Michel, Joe\|Singh, Sharat\|Liu, Xinjun\|Kim, Phillip\|Weitsman, Gregory\|Barber, Paul R\|Vojnovic, Borivoj\|Ng, Tony\|Tejpar, Sabine
PMID:	28032592

2378.
Journal:	Curr Med Res Opin. 2017 Apr;33(4):749-759.
Title:	Targeting the PD-1 pathway: a new hope for gastrointestinal cancers.
Author:	Bilgin, Burak\|Sendur, Mehmet A N\|Bulent Akinci, Muhammed\|Sener Dede, Didem\|Yalcin, Bulent
PMID:	28055269

2379.
Journal:	Pathol Oncol Res. 2017 Oct;23(4):737-744.
Title:	Detection of KRAS Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients.
Author:	Hosoya, Kazuhisa\|Matsusaka, Satoshi\|Kashiwada, Tomomi\|Suzuki, Koichi\|Ureshino, Norio\|Sato, Akemi\|Miki, Yoshio\|Kitera, Kazuki\|Hirai, Mitsuharu\|Hatake, Kiyohiko\|Kimura, Shinya\|Sueoka-Aragane, Naoko
PMID:	28058585

2380.
Journal:	BMC Cancer. 2017 Jan 9;17(1):38.
Title:	Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients.
Author:	Nakayama, Izuma\|Shinozaki, Eiji\|Matsushima, Tomohiro\|Wakatsuki, Takeru\|Ogura, Mariko\|Ichimura, Takashi\|Ozaka, Masato\|Takahari, Daisuke\|Suenaga, Mitsukuni\|Chin, Keisho\|Mizunuma, Nobuyuki\|Yamaguchi, Kensei
PMID:	28068936

2381.
Journal:	Cancer Treat Rev. 2017 Feb;53:61-69.
Title:	Cancer resistance to therapies against the EGFR-RAS-RAF pathway: The role of MEK.
Author:	Martinelli, Erika\|Morgillo, Floriana\|Troiani, Teresa\|Ciardiello, Fortunato
PMID:	28073102

2382.
Journal:	BMC Cancer. 2017 Jan 13;17(1):55.
Title:	Norcantharidin Inhibits cell growth by suppressing the expression and phosphorylation of both EGFR and c-Met in human colon cancer cells.
Author:	Qiu, Peiju\|Wang, Siwen\|Liu, Ming\|Ma, He\|Zeng, Xuan\|Zhang, Meng\|Xu, Lingling\|Cui, Yidi\|Xu, Huixin\|Tang, Yang\|He, Yanli\|Zhang, Lijuan
PMID:	28086832

2383.
Journal:	J Oncol Pract. 2017 Mar;13(3):e185-e196.
Title:	Medical Oncologists' Experiences in Using Genomic Testing for Lung and Colorectal Cancer Care.
Author:	Gray, Stacy W\|Kim, Benjamin\|Sholl, Lynette\|Cronin, Angel\|Parikh, Aparna R\|Klabunde, Carrie N\|Kahn, Katherine L\|Haggstrom, David A\|Keating, Nancy L
PMID:	28095174

2384.
Journal:	PLoS One. 2017 Jan 18;12(1):e0168625.
Title:	The Role of Liquid Based Cytology and Ancillary Techniques in the Peritoneal Washing Analysis: Our Institutional Experience.
Author:	Rossi, Esther\|Bizzarro, Tommaso\|Martini, Maurizio\|Longatto-Filho, Adhemar\|Schmitt, Fernando\|Fagotti, Anna\|Scambia, Giovanni\|Zannoni, Gian Franco
PMID:	28099523

2385.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Jan 25;20(1):28-33.
Title:	[Interpretation of the updates of NCCN 2017 version 1.0 guideline for colorectal cancer].
Author:	Chen, Gong
PMID:	28105616

2386.
Journal:	Mol Oncol. 2017 Feb;11(2):208-219.
Title:	Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing.
Author:	Schmiegel, Wolff\|Scott, Rodney J\|Dooley, Susan\|Lewis, Wendy\|Meldrum, Cliff J\|Pockney, Peter\|Draganic, Brian\|Smith, Steve\|Hewitt, Chelsee\|Philimore, Hazel\|Lucas, Amanda\|Shi, Elva\|Namdarian, Kateh\|Chan, Timmy\|Acosta, Danilo\|Ping-Chang, Su\|Tannapfel, Andrea\|
PMID:	28106345

2387.
Journal:	Int J Mol Sci. 2017 Jan 19;18(1). pii: ijms18010197.
Title:	Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Author:	Marmol, Ines\|Sanchez-de-Diego, Cristina\|Pradilla Dieste, Alberto\|Cerrada, Elena\|Rodriguez Yoldi, Maria Jesus
PMID:	28106826

2388.
Journal:	Future Oncol. 2017 May;13(12):1115-1127.
Title:	Primary tumor site and anti-EGFR monoclonal antibody benefit in metastatic colorectal cancer: a meta-analysis.
Author:	Li, Dandan\|Fu, Qiang\|Li, Man\|Li, Jun\|Yin, Can\|Zhao, Jin\|Li, Feng
PMID:	28110551

2389.
Journal:	Curr Pharm Des. 2017;23(13):2002-2008.
Title:	Current Status and Perspectives Regarding the Therapeutic Potential of Targeting EGFR Pathway by Curcumin in Lung Cancer.
Author:	Shafiee, Mojtaba\|Mohamadzade, Elham\|ShahidSales, Soudabeh\|Khakpouri, Samaneh\|Maftouh, Mina\|Parizadeh, Seyed Alireza\|Hasanian, Seyed Mahdi\|Avan, Amir
PMID:	28117012

2390.
Journal:	Curr Pharm Des. 2017;23(16):2314-2320.
Title:	The Role of Epidermal Growth Factor Receptor in the Management of Gastrointestinal Carcinomas: Present Status and Future Perspectives.
Author:	Mahmood, Malik Quasir\|Shukla, Shakti Dhar\|Dua, Kamal\|Shastri, Madhur D
PMID:	28120720

2391.
Journal:	J Cancer. 2017 Jan 1;8(1):146-151.
Title:	Low Incidence along with Low mRNA Levels of EGFR(vIII) in Prostate and Colorectal Cancers Compared to Glioblastoma.
Author:	Peciak, Joanna\|Stec, Wojciech J\|Treda, Cezary\|Ksiazkiewicz, Magdalena\|Janik, Karolina\|Popeda, Marta\|Smolarz, Maciej\|Rosiak, Kamila\|Hulas-Bigoszewska, Krystyna\|Och, Waldemar\|Rieske, Piotr\|Stoczynska-Fidelus, Ewelina
PMID:	28123609

2392.
Journal:	Food Funct. 2017 Mar 22;8(3):1052-1060.
Title:	Identification of terpenoids from Rubus corchorifolius L. f. leaves and their anti-proliferative effects on human cancer cells.
Author:	Chen, Xuexiang\|Gao, Zili\|Song, Mingyue\|Ouyang, Wen\|Wu, Xian\|Chen, Yunjiao\|Zhou, Liping\|William, Dixon\|Cai, Xiaokun\|Cao, Yong\|Zhou, Shuangde\|Tang, Zhonghai\|Xiao, Hang
PMID:	28134947

2393.
Journal:	Curr Top Med Chem. 2017 Jun 7;17(18):2100-2111.
Title:	Targeted Theranostics Against Solid Cancer Using Metal Bond Milk Protein and Aptamers.
Author:	Chaudhary, Suman\|Kanwar, Rupinder Kaur\|Kanwar, Jagat Rakesh
PMID:	28137239

2394.
Journal:	Drug Des Devel Ther. 2017 Jan 11;11:177-184.
Title:	Immunotherapy for the treatment of colorectal tumors: focus on approved and in-clinical-trial monoclonal antibodies.
Author:	Francoso, Alex\|Simioni, Patricia Ucelli
PMID:	28138221

2395.
Journal:	Arch Pathol Lab Med. 2017 May;141(5):625-657.
Title:	Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.
Author:	Sepulveda, Antonia R\|Hamilton, Stanley R\|Allegra, Carmen J\|Grody, Wayne\|Cushman-Vokoun, Allison M\|Funkhouser, William K\|Kopetz, Scott E\|Lieu, Christopher\|Lindor, Noralane M\|Minsky, Bruce D\|Monzon, Federico A\|Sargent, Daniel J\|Singh, Veena M\|Willis, Joseph
PMID:	28165284

2396.
Journal:	J Clin Oncol. 2017 May 1;35(13):1453-1486.
Title:	Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology.
Author:	Sepulveda, Antonia R\|Hamilton, Stanley R\|Allegra, Carmen J\|Grody, Wayne\|Cushman-Vokoun, Allison M\|Funkhouser, William K\|Kopetz, Scott E\|Lieu, Christopher\|Lindor, Noralane M\|Minsky, Bruce D\|Monzon, Federico A\|Sargent, Daniel J\|Singh, Veena M\|Willis, Joseph
PMID:	28165299

2397.
Journal:	Oncogene. 2017 Jun 22;36(25):3618-3628.
Title:	Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor.
Author:	Weitsman, G\|Mitchell, N J\|Evans, R\|Cheung, A\|Kalber, T L\|Bofinger, R\|Fruhwirth, G O\|Keppler, M\|Wright, Z V F\|Barber, P R\|Gordon, P\|de Koning, T\|Wulaningsih, W\|Sander, K\|Vojnovic, B\|Ameer-Beg, S\|Lythgoe, M\|Arnold, J N\|Arstad, E\|Festy, F\|Hailes, H C\|Tabor,
PMID:	28166195

2398.
Journal:	J Agric Food Chem. 2017 Mar 1;65(8):1566-1573.
Title:	Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.
Author:	Chen, Xuexiang\|Wu, Xian\|Ouyang, Wen\|Gu, Min\|Gao, Zili\|Song, Mingyue\|Chen, Yunjiao\|Lin, Yanyin\|Cao, Yong\|Xiao, Hang
PMID:	28169543

2399.
Journal:	Br J Cancer. 2017 Mar 14;116(6):802-810.
Title:	Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients.
Author:	Malapelle, Umberto\|Mayo de-Las-Casas, Clara\|Rocco, Danilo\|Garzon, Monica\|Pisapia, Pasquale\|Jordana-Ariza, Nuria\|Russo, Maria\|Sgariglia, Roberta\|De Luca, Caterina\|Pepe, Francesco\|Martinez-Bueno, Alejandro\|Morales-Espinosa, Daniela\|Gonzalez-Cao, Maria\|Karac
PMID:	28170370

2400.
Journal:	Mol Oncol. 2017 May;11(5):470-490.
Title:	Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
Author:	Kalimutho, Murugan\|Bain, Amanda L\|Mukherjee, Bipasha\|Nag, Purba\|Nanayakkara, Devathri M\|Harten, Sarah K\|Harris, Janelle L\|Subramanian, Goutham N\|Sinha, Debottam\|Shirasawa, Senji\|Srihari, Sriganesh\|Burma, Sandeep\|Khanna, Kum Kum
PMID:	28173629

2401.
Journal:	Clin Cancer Res. 2017 Jul 15;23(14):3918-3928.
Title:	Circular RNA ciRS-7-A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer.
Author:	Weng, Wenhao\|Wei, Qing\|Toden, Shusuke\|Yoshida, Kazuhiro\|Nagasaka, Takeshi\|Fujiwara, Toshiyoshi\|Cai, Sanjun\|Qin, Huanlong\|Ma, Yanlei\|Goel, Ajay
PMID:	28174233

2402.
Journal:	Mol Oncol. 2017 Jun;11(6):599-611.
Title:	Heat-shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF.
Author:	Konda, John D\|Olivero, Martina\|Musiani, Daniele\|Lamba, Simona\|Di Renzo, Maria F
PMID:	28182330

2403.
Journal:	J Nutr Biochem. 2017 Apr;42:126-133.
Title:	Gene expression changes in colon tissues from colorectal cancer patients following the intake of an ellagitannin-containing pomegranate extract: a randomized clinical trial.
Author:	Nunez-Sanchez, Maria A\|Gonzalez-Sarrias, Antonio\|Garcia-Villalba, Rocio\|Monedero-Saiz, Tamara\|Garcia-Talavera, Noelia V\|Gomez-Sanchez, Maria B\|Sanchez-Alvarez, Carmen\|Garcia-Albert, Ana M\|Rodriguez-Gil, Francisco J\|Ruiz-Marin, Miguel\|Pastor-Quirante, Fran
PMID:	28183047

2404.
Journal:	J Mol Diagn. 2017 Mar;19(2):187-225.
Title:	Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.
Author:	Sepulveda, Antonia R\|Hamilton, Stanley R\|Allegra, Carmen J\|Grody, Wayne\|Cushman-Vokoun, Allison M\|Funkhouser, William K\|Kopetz, Scott E\|Lieu, Christopher\|Lindor, Noralane M\|Minsky, Bruce D\|Monzon, Federico A\|Sargent, Daniel J\|Singh, Veena M\|Willis, Joseph
PMID:	28185757

2405.
Journal:	Oncoimmunology. 2016 Dec 7;6(1):e1255395.
Title:	Prophylactic vaccination targeting ERBB3 decreases polyp burden in a mouse model of human colorectal cancer.
Author:	Bautz, David J\|Sherpa, Ang T\|Threadgill, David W
PMID:	28197371

2406.
Journal:	Oncotarget. 2017 Mar 7;8(10):17164-17190.
Title:	ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer.
Author:	Geissler, Anna-Lena\|Geissler, Miriam\|Kottmann, Daniel\|Lutz, Lisa\|Fichter, Christiane D\|Fritsch, Ralph\|Weddeling, Britta\|Makowiec, Frank\|Werner, Martin\|Lassmann, Silke
PMID:	28199979

2407.
Journal:	Front Immunol. 2017 Feb 6;8:87.
Title:	In Vivo Efficacy of Umbilical Cord Blood Stem Cell-Derived NK Cells in the Treatment of Metastatic Colorectal Cancer.
Author:	Veluchamy, John P\|Lopez-Lastra, Silvia\|Spanholtz, Jan\|Bohme, Fenna\|Kok, Nina\|Heideman, Danielle A M\|Verheul, Henk M W\|Di Santo, James P\|de Gruijl, Tanja D\|van der Vliet, Hans J
PMID:	28220124

2408.
Journal:	Cell Death Dis. 2017 Feb 23;8(2):e2621.
Title:	Oncogenic role of rab escort protein 1 through EGFR and STAT3 pathway.
Author:	Yun, Un-Jung\|Sung, Jee Young\|Park, Seog-Yun\|Ye, Sang-Kyu\|Shim, Jaegal\|Lee, Jae-Seon\|Hibi, Masahiko\|Bae, Young-Ki\|Kim, Yong-Nyun
PMID:	28230863

2409.
Journal:	Case Rep Oncol Med. 2017;2017:6139634.
Title:	Clinical Application of Liquid Biopsy in Targeted Therapy of Metastatic Colorectal Cancer.
Author:	Trojan, Jorg\|Klein-Scory, Susanne\|Koch, Christine\|Schmiegel, Wolff\|Baraniskin, Alexander
PMID:	28232873

2410.
Journal:	J Cancer. 2017 Jan 12;8(2):162-173.
Title:	Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform.
Author:	Peterfia, Balint\|Kalmar, Alexandra\|Patai, Arpad V\|Csabai, Istvan\|Bodor, Andras\|Micsik, Tamas\|Wichmann, Barnabas\|Egedi, Krisztina\|Hollosi, Peter\|Kovalszky, Ilona\|Tulassay, Zsolt\|Molnar, Bela
PMID:	28243320

2411.
Journal:	Orv Hetil. 2017 Mar;158(9):340-344.
Title:	[Does the sidedness determine the first line treatment of irresectable metastatic colorectal cancer?]
Author:	Kullmann, Tamas\|Sipocz, Istvan\|Pinter, Tamas
PMID:	28245681

2412.
Journal:	Med Sci Monit. 2017 Mar 5;23:1146-1155.
Title:	Evaluation of 6-chloro-N-[3,4-disubstituted-1,3-thiazol-2(3H)-ylidene]-1,3-benzothiazol-2-amine Using Drug Design Concept for Their Targeted Activity Against Colon Cancer Cell Lines HCT-116, HCT15, and HT29.
Author:	Zhu, Ming-Li\|Wang, Cui-Yue\|Xu, Cheng-Mian\|Bi, Wei-Ping\|ZHou, Xiu-Ying
PMID:	28259893

2413.
Journal:	Onco Targets Ther. 2017 Feb 23;10:1143-1147.
Title:	Long-term survival after a favorable response to anti-EGFR antibody plus chemotherapy to treat bone marrow metastasis: a case report of KRAS-wildtype rectal cancer.
Author:	Nakamura, Sho\|Fukui, Tadahisa\|Suzuki, Shuhei\|Takeda, Hiroyuki\|Watanabe, Kaname\|Yoshioka, Takashi
PMID:	28260928

2414.
Journal:	Clin Case Rep. 2017 Feb 9;5(3):338-341.
Title:	A novel KRAS gene mutation report in sporadic colorectal cancer, from Northwest of Iran.
Author:	Dolatkhah, Roya\|Somi, Mohammad Hossein\|Kermani, Iraj Asvadi\|Farassati, Faris\|Dastgiri, Saeed
PMID:	28265402

2415.
Journal:	Anticancer Agents Med Chem. 2017;17(10):1389-1400.
Title:	Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
Author:	Bakr, Rania B\|Mehany, Ahmed B M\|Abdellatif, Khaled R A
PMID:	28270084

2416.
Journal:	Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2357-E2364.
Title:	Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids.
Author:	Fumagalli, Arianna\|Drost, Jarno\|Suijkerbuijk, Saskia J E\|van Boxtel, Ruben\|de Ligt, Joep\|Offerhaus, G Johan\|Begthel, Harry\|Beerling, Evelyne\|Tan, Ee Hong\|Sansom, Owen J\|Cuppen, Edwin\|Clevers, Hans\|van Rheenen, Jacco
PMID:	28270604

2417.
Journal:	Clin Cancer Res. 2017 Aug 1;23(15):4146-4154.
Title:	Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author:	Parseghian, Christine M\|Parikh, Nila U\|Wu, Ji Yuan\|Jiang, Zhi-Qin\|Henderson, Laura\|Tian, Feng\|Pastor, Brice\|Ychou, Marc\|Raghav, Kanwal\|Dasari, Arvind\|Fogelman, David R\|Katsiampoura, Anastasia D\|Menter, David G\|Wolff, Robert A\|Eng, Cathy\|Overman, Michael J
PMID:	28280091

2418.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

2419.
Journal:	J Med Genet. 2017 Aug;54(8):567-571.
Title:	Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab.
Author:	Madi, Ayman\|Fisher, David\|Maughan, Timothy S\|Colley, James P\|Meade, Angela M\|Tejpar, Sabine\|Van den Bosch, Ben\|Maynard, Julie\|Humphreys, Vikki\|Wasan, Harpreet\|Adams, Richard A\|Idziaszczyk, Shelley\|Harris, Rebecca\|Kaplan, Richard S\|Cheadle, Jeremy P
PMID:	28283541

2420.
Journal:	PLoS One. 2017 Mar 16;12(3):e0174151.
Title:	In vivo and ex vivo cetuximab sensitivity assay using three-dimensional primary culture system to stratify KRAS mutant colorectal cancer.
Author:	Tashiro, Takahiro\|Okuyama, Hiroaki\|Endo, Hiroko\|Kawada, Kenji\|Ashida, Yasuko\|Ohue, Masayuki\|Sakai, Yoshiharu\|Inoue, Masahiro
PMID:	28301591

2421.
Journal:	J Clin Pathol. 2017 Aug;70(8):720-723.
Title:	Intratumorous heterogeneity for RAS mutations in a treatment-naive colorectal tumour.
Author:	Lunke, Sebastian\|Lee, Belinda\|Kranz, Sevastjan\|Gibbs, Peter\|Waring, Paul\|Christie, Michael
PMID:	28314739

2422.
Journal:	Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2852-E2861.
Title:	Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer.
Author:	Li, Cunxi\|Singh, Bhuminder\|Graves-Deal, Ramona\|Ma, Haiting\|Starchenko, Alina\|Fry, William H\|Lu, Yuanyuan\|Wang, Yang\|Bogatcheva, Galina\|Khan, Mohseen P\|Milne, Ginger L\|Zhao, Shilin\|Ayers, Gregory Daniel\|Li, Nenggan\|Hu, Huaying\|Washington, Mary Kay\|Yeatman,
PMID:	28320945

2423.
Journal:	Cancer Lett. 2017 Jun 28;396:94-102.
Title:	Co-targeting of EGFR and autophagy signaling is an emerging treatment strategy in metastatic colorectal cancer.
Author:	Koustas, Evangelos\|Karamouzis, Michalis V\|Mihailidou, Chrysovalantou\|Schizas, Dimitrios\|Papavassiliou, Athanasios G
PMID:	28323034

2424.
Journal:	Interdiscip Sci. 2017 Mar 27. pii: 10.1007/s12539-017-0227-6.
Title:	EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-Cysteine Sulfoxide.
Author:	Roy, Nabarun\|Nazeem, P A\|Babu, T D\|Abida, P S\|Narayanankutty, Arunaksharan\|Valsalan, Ravisankar\|Valsala, P A\|Raghavamenon, Achuthan C
PMID:	28349439

2425.
Journal:	Clin Colorectal Cancer. 2017 Dec;16(4):247-251.
Title:	HER2 as an Emerging Oncotarget for Colorectal Cancer Treatment After Failure of Anti-Epidermal Growth Factor Receptor Therapy.
Author:	Takegawa, Naoki\|Yonesaka, Kimio
PMID:	28363756

2426.
Journal:	Cancer Discov. 2017 Jun;7(6):610-619.
Title:	A Phase Ib Dose-Escalation Study of Encorafenib and Cetuximab with or without Alpelisib in Metastatic BRAF-Mutant Colorectal Cancer.
Author:	van Geel, Robin M J M\|Tabernero, Josep\|Elez, Elena\|Bendell, Johanna C\|Spreafico, Anna\|Schuler, Martin\|Yoshino, Takayuki\|Delord, Jean-Pierre\|Yamada, Yasuhide\|Lolkema, Martijn P\|Faris, Jason E\|Eskens, Ferry A L M\|Sharma, Sunil\|Yaeger, Rona\|Lenz, Heinz-Josef
PMID:	28363909

2427.
Journal:	Mol Cell Biochem. 2017 Jul;431(1-2):45-54.
Title:	MicroR-545 mediates colorectal cancer cells proliferation through up-regulating epidermal growth factor receptor expression in HOTAIR long non-coding RNA dependent.
Author:	Huang, Xinli\|Lu, Sen
PMID:	28364379

2428.
Journal:	Expert Opin Ther Pat. 2017 May;27(5):527-538.
Title:	Methods of selecting combination therapy for colorectal cancer patients: a patent evaluation of US20160025730A1.
Author:	Plano, Daniel\|Alcolea, Veronica\|Sanmartin, Carmen\|Sharma, Arun K
PMID:	28366103

2429.
Journal:	Handb Exp Pharmacol. 2017 Apr 6.
Title:	Plasticity of Resistance and Sensitivity to Anti-Epidermal Growth Factor Receptor Inhibitors in Metastatic Colorectal Cancer.
Author:	Sartore-Bianchi, Andrea\|Siena, Salvatore
PMID:	28382467

2430.
Journal:	Crit Rev Clin Lab Sci. 2017 May;54(3):205-218.
Title:	Using circulating cell-free DNA to monitor personalized cancer therapy.
Author:	Oellerich, Michael\|Schutz, Ekkehard\|Beck, Julia\|Kanzow, Philipp\|Plowman, Piers N\|Weiss, Glen J\|Walson, Philip D
PMID:	28393575

2431.
Journal:	Sensors (Basel). 2017 Apr 11;17(4). pii: s17040831.
Title:	Miniaturized Real-Time PCR on a Q3 System for Rapid KRAS Genotyping.
Author:	Guarnaccia, Maria\|Iemmolo, Rosario\|Petralia, Salvatore\|Conoci, Sabrina\|Cavallaro, Sebastiano
PMID:	28398227

2432.
Journal:	Gastroenterology. 2017 Jul;153(1):178-190.e10.
Title:	EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.
Author:	Srivatsa, Sriram\|Paul, Mariel C\|Cardone, Claudia\|Holcmann, Martin\|Amberg, Nicole\|Pathria, Paulina\|Diamanti, Michaela A\|Linder, Markus\|Timelthaler, Gerald\|Dienes, Hans P\|Kenner, Lukas\|Wrba, Fritz\|Prager, Gerald W\|Rose-John, Stefan\|Eferl, Robert\|Liguori, Gi
PMID:	28400195

2433.
Journal:	Acta Cir Bras. 2017 Mar;32(3):243-250.
Title:	Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors.
Author:	Carvalho, Thais Inacio de\|Novais, Paulo Cezar\|Lizarte, Fermino Sanches Neto\|Sicchieri, Renata Danielle\|Rosa, Marcella Suelma Torrecillas\|Carvalho, Camila Albuquerque Mello de\|Tirapelli, Daniela Pretti da Cunha\|Peria, Fernanda Maris\|Rocha, Jose Joaquim Rib
PMID:	28403349

2434.
Journal:	Oncotarget. 2017 Apr 18;8(16):27454-27470.
Title:	Multi-factorial modulation of colorectal carcinoma cells motility - partial coordination by the tetraspanin Co-029/tspan8.
Author:	Zhu, Yingying\|Ailane, Naouel\|Sala-Valdes, Monica\|Haghighi-Rad, Farhad\|Billard, Martine\|Nguyen, Viet\|Saffroy, Raphael\|Lemoine, Antoinette\|Rubinstein, Eric\|Boucheix, Claude\|Greco, Celine
PMID:	28418857

2435.
Journal:	Ann Oncol. 2017 Jun 1;28(6):1325-1332.
Title:	Plasma ctDNA RAS mutation analysis for the diagnosis and treatment monitoring of metastatic colorectal cancer patients.
Author:	Vidal, J\|Muinelo, L\|Dalmases, A\|Jones, F\|Edelstein, D\|Iglesias, M\|Orrillo, M\|Abalo, A\|Rodriguez, C\|Brozos, E\|Vidal, Y\|Candamio, S\|Vazquez, F\|Ruiz, J\|Guix, M\|Visa, L\|Sikri, V\|Albanell, J\|Bellosillo, B\|Lopez, R\|Montagut, C
PMID:	28419195

2436.
Journal:	Oncotarget. 2017 May 23;8(21):35138-35153.
Title:	Toll like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer.
Author:	Maitra, Radhashree\|Augustine, Titto\|Dayan, Yitzchak\|Chandy, Carol\|Coffey, Matthew\|Goel, Sanjay
PMID:	28422714

2437.
Journal:	JCI Insight. 2017 Apr 20;2(8). pii: 90380.
Title:	First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients.
Author:	Subbiah, Vivek\|Khawaja, Muhammad Rizwan\|Hong, David S\|Amini, Behrang\|Yungfang, Jiang\|Liu, Hui\|Johnson, Adrienne\|Schrock, Alexa B\|Ali, Siraj M\|Sun, James X\|Fabrizio, David\|Piha-Paul, Sarina\|Fu, Siqing\|Tsimberidou, Apostolia M\|Naing, Aung\|Janku, Filip\|Karp,
PMID:	28422758

2438.
Journal:	Oncotarget. 2017 Mar 28;8(13):21754-21769.
Title:	The addition of celecoxib improves the antitumor effect of cetuximab in colorectal cancer: role of EGFR-RAS-FOXM1-beta- catenin signaling axis.
Author:	Valverde, Araceli\|Penarando, Jon\|Canas, Amanda\|Lopez-Sanchez, Laura M\|Conde, Francisco\|Guil-Luna, Silvia\|Hernandez, Vanessa\|Villar, Carlos\|Morales-Estevez, Cristina\|de la Haba-Rodriguez, Juan\|Aranda, Enrique\|Rodriguez-Ariza, Antonio
PMID:	28423516

2439.
Journal:	Onco Targets Ther. 2017 Apr 7;10:2033-2044.
Title:	Patient considerations in metastatic colorectal cancer - role of panitumumab.
Author:	Rogers, Jane E
PMID:	28435294

2440.
Journal:	Onco Targets Ther. 2017 Apr 7;10:2045-2056.
Title:	Silencing CDR1as inhibits colorectal cancer progression through regulating microRNA-7.
Author:	Tang, Wentao\|Ji, Meiling\|He, Guodong\|Yang, Liangliang\|Niu, Zhengchuan\|Jian, Mi\|Wei, Ye\|Ren, Li\|Xu, Jianmin
PMID:	28435295

2441.
Journal:	Sci Rep. 2017 Apr 24;7:46632.
Title:	Rational design of non-resistant targeted cancer therapies.
Author:	Martinez-Jimenez, Francisco\|Overington, John P\|Al-Lazikani, Bissan\|Marti-Renom, Marc A
PMID:	28436422

2442.
Journal:	Hum Pathol. 2017 Jun;64:179-185.
Title:	Clinicopathological, immunohistochemical, and mutational analyses of pulmonary enteric adenocarcinoma: usefulness of SATB2 and beta-catenin immunostaining for differentiation from metastatic colorectal carcinoma.
Author:	Matsushima, Jun\|Yazawa, Takuya\|Suzuki, Masaki\|Takahashi, Yoko\|Ota, Satoshi\|Nakajima, Takahiro\|Yoshino, Ichiro\|Yokose, Tomoyuki\|Inoue, Toru\|Kawahara, Kunimitsu\|Nakatani, Yukio
PMID:	28438615

2443.
Journal:	J Control Release. 2017 Jul 28;258:196-207.
Title:	EGFR-targeted micelles containing near-infrared dye for enhanced photothermal therapy in colorectal cancer.
Author:	Shih, Ying-Hsia\|Luo, Tsai-Yueh\|Chiang, Ping-Fang\|Yao, Cheng-Jung\|Lin, Wuu-Jyh\|Peng, Cheng-Liang\|Shieh, Ming-Jium
PMID:	28445743

2444.
Journal:	Oncotarget. 2017 Apr 11;8(15):25251-25260.
Title:	RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer.
Author:	Miao, Fei\|Zhang, Mengmeng\|Zhao, Yuechao\|Li, Xiaolu\|Yao, Rongyan\|Wu, Fan\|Huang, Rong\|Li, Kai\|Miao, Shiying\|Ma, Changwu\|Ju, Hongge\|Song, Wei\|Wang, Linfang
PMID:	28445956

2445.
Journal:	Clin Cancer Res. 2017 Aug 15;23(16):4753-4760.
Title:	Clinical Features and Outcomes of Patients with Colorectal Cancers Harboring NRAS Mutations.
Author:	Cercek, Andrea\|Braghiroli, Maria Ignez\|Chou, Joanne F\|Hechtman, Jaclyn F\|Kemeny, Nancy\|Saltz, Leonard\|Capanu, Marinela\|Yaeger, Rona
PMID:	28446505

2446.
Journal:	Acta Oncol. 2017 May;56(5):639-645.
Title:	Risk factors for brain metastases in patients with metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Hogdall, Estrid\|Poulsen, Tim Svenstrup\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Christensen, Ib Jarle\|Nielsen, Dorte
PMID:	28447565

2447.
Journal:	Mol Clin Oncol. 2017 Mar;6(3):403-408.
Title:	Role of RAS mutation status as a prognostic factor for patients with advanced colorectal cancer treated with first-line chemotherapy based on fluoropyrimidines and oxaliplatin, with or without bevavizumab: A retrospective analysis.
Author:	Garde Noguera, Javier\|Jantus-Lewintre, Eloisa\|Gil-Raga, Mireia\|Evgenyeva, Elena\|Macia Escalante, Sonia\|Llombart-Cussac, Antonio\|Camps Herrero, Carlos
PMID:	28451421

2448.
Journal:	Sci Rep. 2017 May 4;7(1):1502.
Title:	Rationally co-targeting divergent pathways in KRAS wild-type colorectal cancers by CANscript technology reveals tumor dependence on Notch and Erbb2.
Author:	Brijwani, Nilesh\|Jain, Misti\|Dhandapani, Muthu\|Zahed, Farrah\|Mukhopadhyay, Pragnashree\|Biswas, Manjusha\|Khatri, Deepak\|Radhakrishna, Vinod D\|Majumder, Biswanath\|Radhakrishnan, Padhma\|Thiyagarajan, Saravanan
PMID:	28473715

2449.
Journal:	Anticancer Res. 2017 May;37(5):2255-2263.
Title:	Up-regulation of SLC9A9 Promotes Cancer Progression and Is Involved in Poor Prognosis in Colorectal Cancer.
Author:	Ueda, Masami\|Iguchi, Tomohiro\|Masuda, Takaaki\|Komatsu, Hisateru\|Nambara, Sho\|Sakimura, Shotaro\|Hirata, Hidenari\|Uchi, Ryutaro\|Eguchi, Hidetoshi\|Ito, Shuhei\|Sugimachi, Keishi\|Mizushima, Tsunekazu\|Doki, Yuichiro\|Mori, Masaki\|Mimori, Koshi
PMID:	28476790

2450.
Journal:	Mol Oncol. 2017 Aug;11(8):1065-1077.
Title:	Panitumumab interaction with TAS-102 leads to combinational anticancer effects via blocking of EGFR-mediated tumor response to trifluridine.
Author:	Baba, Yuji\|Tamura, Toshiya\|Satoh, Yoshihiko\|Gotou, Masamitsu\|Sawada, Hiroshi\|Ebara, Shunsuke\|Shibuya, Kazunori\|Soeda, Jumpei\|Nakamura, Kazuhide
PMID:	28486761

2451.
Journal:	Oncotarget. 2017 Jul 11;8(28):45898-45917.
Title:	Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapy.
Author:	Kasper, Stefan\|Reis, Henning\|Ziegler, Sophie\|Nothdurft, Silke\|Mueller, Andre\|Goetz, Moritz\|Wiesweg, Marcel\|Phasue, Jeannette\|Ting, Saskia\|Wieczorek, Sarah\|Even, Anna\|Worm, Karl\|Pogorzelski, Michael\|Breitenbuecher, Sandra\|Meiler, Johannes\|Paul, Andreas\|Tra
PMID:	28507280

2452.
Journal:	Pathol Res Pract. 2017 Jun;213(6):639-642.
Title:	CPEB4 immunohistochemical expression is associated to prognosis in stage IV colorectal carcinoma.
Author:	Cortes-Guiral, D\|Pastor-Iodate, C\|Diaz Del Arco, C\|Del Puerto-Nevado, L\|Fernandez-Acenero, M J
PMID:	28551384

2453.
Journal:	Pathol Res Pract. 2017 Jun;213(6):606-611.
Title:	Influence of mucinous and necrotic tissue in colorectal cancer samples on KRAS mutation analysis.
Author:	Buttner, Juliane\|Lehmann, Annika\|Klauschen, Frederick\|Hummel, Michael\|Lenze, Dido\|Dietel, Manfred\|Johrens, Korinna
PMID:	28551386

2454.
Journal:	Oncol Rep. 2017 Jul;38(1):263-270.
Title:	EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells.
Author:	Cuyas, Elisabet\|Queralt, Bernardo\|Martin-Castillo, Begona\|Bosch-Barrera, Joaquim\|Menendez, Javier A
PMID:	28560458

2455.
Journal:	Nat Commun. 2017 May 31;8:15107.
Title:	Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.
Author:	Isella, Claudio\|Brundu, Francesco\|Bellomo, Sara E\|Galimi, Francesco\|Zanella, Eugenia\|Porporato, Roberta\|Petti, Consalvo\|Fiori, Alessandro\|Orzan, Francesca\|Senetta, Rebecca\|Boccaccio, Carla\|Ficarra, Elisa\|Marchionni, Luigi\|Trusolino, Livio\|Medico, Enzo\|Ber
PMID:	28561063

2456.
Journal:	J Surg Oncol. 2017 Nov;116(6):706-715.
Title:	Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients.
Author:	Handa, Tadashi\|Katayama, Ayaka\|Yokobori, Takehiko\|Yamane, Arito\|Horiguchi, Jun\|Kawabata-Iwakawa, Reika\|Rokudai, Susumu\|Bao, Pinjie\|Gombodorj, Navchaa\|Altan, Bolag\|Kaira, Kyoichi\|Asao, Takayuki\|Kuwano, Hiroyuki\|Nishiyama, Masahiko\|Oyama, Tetsunari
PMID:	28570747

2457.
Journal:	Cell J. 2017 Spring;19(Suppl 1):113-117.
Title:	Coexistence of KRAS and BRAF Mutations in Colorectal Cancer: A Case Report Supporting The Concept of Tumoral Heterogeneity.
Author:	Larki, Pegah\|Gharib, Ehsan\|Yaghoob Taleghani, Mohammad\|Khorshidi, Fatemeh\|Nazemalhosseini-Mojarad, Ehsan\|Asadzadeh Aghdaei, Hamid
PMID:	28580315

2458.
Journal:	BMC Cancer. 2017 Jun 5;17(1):403.
Title:	The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients.
Author:	Won, Daeyoun David\|Lee, Jae Im\|Lee, In Kyu\|Oh, Seong-Taek\|Jung, Eun Sun\|Lee, Sung Hak
PMID:	28583095

2459.
Journal:	Biomed Pharmacother. 2017 Aug;92:696-706.
Title:	Libidibia ferrea presents antiproliferative, apoptotic and antioxidant effects in a colorectal cancer cell line.
Author:	Guerra, Andreza Conceicao Veras de Aguiar\|Soares, Luiz Alberto Lira\|Ferreira, Magda Rhayanny Assuncao\|Araujo, Aurigena Antunes de\|Rocha, Hugo Alexandre de Oliveira\|Medeiros, Juliana Silva de\|Cavalcante, Romulo Dos Santos\|Junior, Raimundo Fernandes de Arau
PMID:	28586741

2460.
Journal:	PLoS One. 2017 Jun 7;12(6):e0178676.
Title:	The impact of de novo liver metastasis on clinical outcome in patients with advanced non-small-cell lung cancer.
Author:	Chang, Yu-Ping\|Chen, Yu-Mu\|Lai, Chien-Hao\|Lin, Chiung-Yu\|Fang, Wen-Feng\|Huang, Cherng-Hua\|Li, Shau-Hsuan\|Chen, Hung-Chen\|Wang, Chin-Chou\|Lin, Meng-Chih
PMID:	28591157

2461.
Journal:	Oncotarget. 2017 Jun 20;8(25):39945-39962.
Title:	BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.
Author:	Deihimi, Safoora\|Lev, Avital\|Slifker, Michael\|Shagisultanova, Elena\|Xu, Qifang\|Jung, Kyungsuk\|Vijayvergia, Namrata\|Ross, Eric A\|Xiu, Joanne\|Swensen, Jeffrey\|Gatalica, Zoran\|Andrake, Mark\|Dunbrack, Roland L\|El-Deiry, Wafik S
PMID:	28591715

2462.
Journal:	J Cancer. 2017 Apr 9;8(7):1113-1122.
Title:	A Combined ULBP2 and SEMA5A Expression Signature as a Prognostic and Predictive Biomarker for Colon Cancer.
Author:	Demirkol, Secil\|Gomceli, Ismail\|Isbilen, Murat\|Dayanc, Baris Emre\|Tez, Mesut\|Bostanci, Erdal Birol\|Turhan, Nesrin\|Akoglu, Musa\|Ozyerli, Ezgi\|Durdu, Sevi\|Konu, Ozlen\|Nissan, Aviram\|Gonen, Mithat\|Gure, Ali Osmay
PMID:	28607584

2463.
Journal:	Mol Cancer Ther. 2017 Oct;16(10):2178-2190.
Title:	A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF-mutated and BCL2L1-amplified Colorectal Cancers.
Author:	Cho, Sung-Yup\|Han, Jee Yun\|Na, Deukchae\|Kang, Wonyoung\|Lee, Ahra\|Kim, Jooyoung\|Lee, Jieun\|Min, Seoyeon\|Kang, Jinjoo\|Chae, Jeesoo\|Kim, Jong-Il\|Park, Hansoo\|Lee, Won-Suk\|Lee, Charles
PMID:	28611106

2464.
Journal:	Clin Cancer Res. 2017 Sep 15;23(18):5547-5560.
Title:	Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with BRAF or KRAS Mutations.
Author:	Yao, Yung-Mae M\|Donoho, Gregory P\|Iversen, Philip W\|Zhang, Youyan\|Van Horn, Robert D\|Forest, Amelie\|Novosiadly, Ruslan D\|Webster, Yue Wang\|Ebert, Philip\|Bray, Steven\|Ting, Jason C\|Aggarwal, Amit\|Henry, James R\|Tiu, Ramon V\|Plowman, Gregory D\|Peng, Sheng-B
PMID:	28611205

2465.
Journal:	Mol Oncol. 2017 Sep;11(9):1263-1272.
Title:	Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights.
Author:	Dienstmann, Rodrigo\|Elez, Elena\|Argiles, Guillem\|Matos, Ignacio\|Sanz-Garcia, Enrique\|Ortiz, Carolina\|Macarulla, Teresa\|Capdevila, Jaume\|Alsina, Maria\|Sauri, Tamara\|Verdaguer, Helena\|Vilaro, Marta\|Ruiz-Pace, Fiorella\|Viaplana, Cristina\|Garcia, Ariadna\|Land
PMID:	28618197

2466.
Journal:	Br J Cancer. 2017 Jul 25;117(3):358-366.
Title:	Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.
Author:	Mariani, Sara\|Bertero, Luca\|Osella-Abate, Simona\|Di Bello, Cristiana\|Francia di Celle, Paola\|Coppola, Vittoria\|Sapino, Anna\|Cassoni, Paola\|Marchio, Caterina
PMID:	28618430

2467.
Journal:	Br J Cancer. 2017 Jul 25;117(3):315-321.
Title:	The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab.
Author:	Demurtas, Laura\|Puzzoni, Marco\|Giampieri, Riccardo\|Ziranu, Pina\|Pusceddu, Valeria\|Mandolesi, Alessandra\|Cremolini, Chiara\|Masi, Gianluca\|Gelsomino, Fabio\|Antoniotti, Carlotta\|Loretelli, Cristian\|Meriggi, Fausto\|Zaniboni, Alberto\|Falcone, Alfredo\|Cascinu,
PMID:	28632725

2468.
Journal:	Int J Med Sci. 2017 Apr 9;14(6):515-522.
Title:	Nuclear Expression of GS28 Protein: A Novel Biomarker that Predicts Prognosis in Colorectal Cancers.
Author:	Lee, Sung Hak\|Yoo, Hyung Jae\|Rim, Do Eun\|Cui, Yinji\|Lee, Ahwon\|Jung, Eun Sun\|Oh, Seung Taek\|Kim, Jun Gi\|Kwon, Oh-Joo\|Kim, Su Young\|Jeong, Seong-Whan
PMID:	28638266

2469.
Journal:	Mol Diagn Ther. 2017 Oct;21(5):571-579.
Title:	Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.
Author:	Ma, Wanlong\|Brodie, Steven\|Agersborg, Sally\|Funari, Vincent A\|Albitar, Maher
PMID:	28639239

2470.
Journal:	NPJ Syst Biol Appl. 2017 Jun 2;3:14.
Title:	Clinical responses to ERK inhibition in BRAF(V600E)-mutant colorectal cancer predicted using a computational model.
Author:	Kirouac, Daniel C\|Schaefer, Gabriele\|Chan, Jocelyn\|Merchant, Mark\|Orr, Christine\|Huang, Shih-Min A\|Moffat, John\|Liu, Lichuan\|Gadkar, Kapil\|Ramanujan, Saroja
PMID:	28649441

2471.
Journal:	Virchows Arch. 2017 Dec;471(6):721-729.
Title:	RAS screening in colorectal cancer: a comprehensive analysis of the results from the UK NEQAS colorectal cancer external quality assurance schemes (2009-2016).
Author:	Richman, Susan D\|Fairley, Jennifer\|Butler, Rachel\|Deans, Zandra C
PMID:	28653203

2472.
Journal:	Int J Biol Markers. 2017 Oct 31;32(4):e474-e477.
Title:	Discordance in RAS mutations between primary colon tumor and metastases: a real event or a matter of methodology?
Author:	De Stefano, Alfonso\|Rosanova, Mario\|Malapelle, Umberto\|Martini, Maurizio\|De Falco, Stefano\|Attademo, Laura\|Fiore, Giovanni\|Cenci, Tonia\|Bellevicine, Claudio\|De Placido, Sabino\|Troncone, Giancarlo\|Carlomagno, Chiara
PMID:	28665451

2473.
Journal:	Int J Cancer. 2017 Oct 15;141(8):1614-1629.
Title:	MicroRNA 375 regulates proliferation and migration of colon cancer cells by suppressing the CTGF-EGFR signaling pathway.
Author:	Alam, Khondoker Jahengir\|Mo, Ji-Su\|Han, Seol-Hee\|Park, Won-Cheol\|Kim, Hun-Soo\|Yun, Ki-Jung\|Chae, Soo-Cheon
PMID:	28670764

2474.
Journal:	Health Technol Assess. 2017 Jun;21(38):1-294.
Title:	The clinical effectiveness and cost-effectiveness of cetuximab (review of technology appraisal no. 176) and panitumumab (partial review of technology appraisal no. 240) for previously untreated metastatic colorectal cancer: a systematic review and economi
Author:	Huxley, Nicola\|Crathorne, Louise\|Varley-Campbell, Jo\|Tikhonova, Irina\|Snowsill, Tristan\|Briscoe, Simon\|Peters, Jaime\|Bond, Mary\|Napier, Mark\|Hoyle, Martin
PMID:	28682222

2475.
Journal:	Mol Clin Oncol. 2017 Jul;7(1):113-120.
Title:	Heterogeneity in the colorectal primary tumor and the synchronous resected liver metastases prior to and after treatment with an anti-EGFR monoclonal antibody.
Author:	Adua, Daniela\|Di Fabio, Francesca\|Ercolani, Giorgio\|Fiorentino, Michelangelo\|Gruppioni, Elisa\|Altimari, Annalisa\|Rojas Limpe, Fabiola Lorena\|Normanno, Nicola\|Pinna, Antonio Daniele\|Pinto, Carmine
PMID:	28685087

2476.
Journal:	Gene. 2017 Sep 5;627:484-490.
Title:	Systemic analysis of different colorectal cancer cell lines and TCGA datasets identified IGF-1R/EGFR-PPAR-CASPASE axis as important indicator for radiotherapy sensitivity.
Author:	Chen, Lin\|Zhu, Zhe\|Gao, Wei\|Jiang, Qixin\|Yu, Jiangming\|Fu, Chuangang
PMID:	28687332

2477.
Journal:	Cancer Metastasis Rev. 2017 Jun;36(2):395-406.
Title:	Optimal use of anti-EGFR monoclonal antibodies for patients with advanced colorectal cancer: a meta-analysis.
Author:	van Helden, E J\|Menke-van der Houven van Oordt, C W\|Heymans, M W\|Ket, J C F\|van den Oord, R\|Verheul, H M W
PMID:	28695301

2478.
Journal:	Mol Cancer Res. 2017 Oct;15(10):1445-1454.
Title:	EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer.
Author:	Okada, Yasuyuki\|Kimura, Tetsuo\|Nakagawa, Tadahiko\|Okamoto, Koichi\|Fukuya, Akira\|Goji, Takahiro\|Fujimoto, Shota\|Sogabe, Masahiro\|Miyamoto, Hiroshi\|Muguruma, Naoki\|Tsuji, Yasushi\|Okahisa, Toshiya\|Takayama, Tetsuji
PMID:	28698359

2479.
Journal:	Int J Mol Sci. 2017 Jul 17;18(7). pii: ijms18071547.
Title:	Non-Coding RNAs as Predictive Biomarkers to Current Treatment in Metastatic Colorectal Cancer.
Author:	Garajova, Ingrid\|Ferracin, Manuela\|Porcellini, Elisa\|Palloni, Andrea\|Abbati, Francesca\|Biasco, Guido\|Brandi, Giovanni
PMID:	28714940

2480.
Journal:	J Enzyme Inhib Med Chem. 2017 Dec;32(1):935-944.
Title:	Synthesis, anticancer and apoptosis-inducing activities of quinazoline-isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies.
Author:	El-Azab, Adel S\|Al-Dhfyan, Abdullah\|Abdel-Aziz, Alaa A-M\|Abou-Zeid, Laila A\|Alkahtani, Hamad M\|Al-Obaid, Abdulrahman M\|Al-Gendy, Manal A
PMID:	28718672

2481.
Journal:	Rom J Morphol Embryol. 2017;58(2):655-663.
Title:	Morphology with immunohistochemical and genetic profiling of high-grade neuroendocrine carcinoma of colon - a case report with review of literature.
Author:	Wincewicz, Andrzej\|Kowalik, Artur\|Zieba, Sebastian\|Sulkowski, Stanislaw\|Gozdz, Stanislaw
PMID:	28730258

2482.
Journal:	Cell Death Differ. 2017 Nov;24(11):1937-1947.
Title:	Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells.
Author:	Piyush, Tushar\|Chacko, Anisha R\|Sindrewicz, Paulina\|Hilkens, John\|Rhodes, Jonathan M\|Yu, Lu-Gang
PMID:	28731466

2483.
Journal:	J Gastrointest Oncol. 2017 Jun;8(3):387-404.
Title:	Personalized and precision medicine: integrating genomics into treatment decisions in gastrointestinal malignancies.
Author:	Au, Trang H\|Wang, Kai\|Stenehjem, David\|Garrido-Laguna, Ignacio
PMID:	28736627

2484.
Journal:	J Gastrointest Oncol. 2017 Jun;8(3):405-417.
Title:	Predictive and prognostic biomarkers in personalized gastrointestinal cancer treatment.
Author:	Verdaguer, Helena\|Sauri, Tamara\|Macarulla, Teresa
PMID:	28736628

2485.
Journal:	J Gastrointest Oncol. 2017 Jun;8(3):499-512.
Title:	Primary and acquired resistance to biologic therapies in gastrointestinal cancers.
Author:	Lubner, Sam J\|Uboha, Nataliya V\|Deming, Dustin A
PMID:	28736637

2486.
Journal:	Cell Physiol Biochem. 2017;42(4):1559-1574.
Title:	A Novel Role for MiR-520a-3p in Regulating EGFR Expression in Colorectal Cancer.
Author:	Zhang, Rui\|Liu, Rui\|Liu, Chang\|Niu, Yahan\|Zhang, Jianguo\|Guo, Baoliang\|Zhang, Chen-Yu\|Li, Jing\|Yang, Jie\|Chen, Xi
PMID:	28738328

2487.
Journal:	Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt B):2228-2239.
Title:	Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.
Author:	Dempsey, Peter J
PMID:	28739265

2488.
Journal:	Lab Invest. 2017 Nov;97(11):1343-1353.
Title:	Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth.
Author:	Li, Dandan\|Zhang, Youyu\|Liu, Kun\|Zhao, Yujie\|Xu, Beibei\|Xu, Liang\|Tan, Li\|Tian, Yuan\|Li, Cunxi\|Zhang, Wenqing\|Cao, Hanwei\|Zhan, Yan-Yan\|Hu, Tianhui
PMID:	28759012

2489.
Journal:	Oncogene. 2017 Nov 16;36(46):6480-6489.
Title:	Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma.
Author:	Fujishita, T\|Kojima, Y\|Kajino-Sakamoto, R\|Taketo, M M\|Aoki, M
PMID:	28759045

2490.
Journal:	Lancet Oncol. 2017 Sep;18(9):1172-1181.
Title:	TAS-102 plus bevacizumab for patients with metastatic colorectal cancer refractory to standard therapies (C-TASK FORCE): an investigator-initiated, open-label, single-arm, multicentre, phase 1/2 study.
Author:	Kuboki, Yasutoshi\|Nishina, Tomohiro\|Shinozaki, Eiji\|Yamazaki, Kentaro\|Shitara, Kohei\|Okamoto, Wataru\|Kajiwara, Takeshi\|Matsumoto, Toshihiko\|Tsushima, Takahiro\|Mochizuki, Nobuo\|Nomura, Shogo\|Doi, Toshihiko\|Sato, Akihiro\|Ohtsu, Atsushi\|Yoshino, Takayuki
PMID:	28760399

2491.
Journal:	J Transl Med. 2017 Aug 1;15(1):167.
Title:	Comparative analysis of the EGFR, HER2, c-MYC, and MET variations in colorectal cancer determined by three different measures: gene copy number gain, amplification status and the 2013 ASCO/CAP guideline criterion for HER2 testing of breast cancer.
Author:	Kwak, Yoonjin\|Yun, Sumi\|Nam, Soo Kyung\|Seo, An Na\|Lee, Kyu Sang\|Shin, Eun\|Oh, Heung-Kwon\|Kim, Duck Woo\|Kang, Sung Bum\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	28764718

2492.
Journal:	Cancer Cell Int. 2017 Aug 7;17:75.
Title:	Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer.
Author:	Liu, Jingwei\|Li, Hao\|Sun, Liping\|Wang, Zhenning\|Xing, Chengzhong\|Yuan, Yuan
PMID:	28794688

2493.
Journal:	Ther Adv Med Oncol. 2017 Aug;9(8):551-564.
Title:	Recent developments in the treatment of metastatic colorectal cancer.
Author:	Loree, Jonathan M\|Kopetz, Scott
PMID:	28794806

2494.
Journal:	J Extracell Vesicles. 2017 Jul 16;6(1):1340745.
Title:	Characterisation of tumour-derived microvesicles in cancer patients' blood and correlation with clinical outcome.
Author:	Menck, Kerstin\|Bleckmann, Annalen\|Wachter, Astrid\|Hennies, Bianca\|Ries, Lena\|Schulz, Matthias\|Balkenhol, Marko\|Pukrop, Tobias\|Schatlo, Bawarjan\|Rost, Ulrike\|Wenzel, Dirk\|Klemm, Florian\|Binder, Claudia
PMID:	28804596

2495.
Journal:	Chin J Nat Med. 2017 Jul;15(7):505-514.
Title:	Mesua ferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways.
Author:	Asif, Muhammad\|Shafaei, Armaghan\|Abdul Majid, Aman Shah\|Ezzat, Mohammed Oday\|Dahham, Saad S\|Ahamed, Mohamed B Khadeer\|Oon, Chern Ein\|Abdul Majid, Amin Malik Shah
PMID:	28807224

2496.
Journal:	J Cancer. 2017 Jul 20;8(12):2263-2268.
Title:	MAP2K1 Mutation in Colorectal Cancer Patients: Therapeutic Challenge Using Patient-Derived Tumor Cell Lines.
Author:	Kim, J E\|Kim, K K\|Kim, S Y\|Lee, J\|Park, S H\|Park, J O\|Park, Y S\|Lim, H Y\|Kang, W K\|Kim, S T
PMID:	28819429

2497.
Journal:	Theranostics. 2017 Jun 25;7(10):2620-2633.
Title:	A High-Affinity Repebody for Molecular Imaging of EGFR-Expressing Malignant Tumors.
Author:	Yun, Misun\|Kim, Dong-Yeon\|Lee, Joong-Jae\|Kim, Hyeon-Sik\|Kim, Hyung-Seok\|Pyo, Ayoung\|Ryu, Yiseul\|Kim, Tae-Yoon\|Zheng, Jin Hai\|Yoo, Su Woong\|Hyun, Hoon\|Oh, Gyungseok\|Jeong, Jaeho\|Moon, Myeongju\|Min, Jung-Hyun\|Kwon, Seong Young\|Kim, Jung Young\|Chung, Euiheon
PMID:	28819451

2498.
Journal:	Cancer Lett. 2017 Oct 28;407:93-105.
Title:	Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death.
Author:	Oberthur, Rabea\|Seemann, Henning\|Gehrig, Julia\|Rave-Frank, Margret\|Bremmer, Felix\|Halpape, Rovena\|Conradi, Lena-Christin\|Scharf, Jens-Gerd\|Burfeind, Peter\|Kaulfuss, Silke
PMID:	28823963

2499.
Journal:	Sci Rep. 2017 Aug 29;7(1):9814.
Title:	Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition.
Author:	Lin, Yu-Wei\|Raj, Emmanuel Naveen\|Liao, Wei-Siang\|Lin, Johnson\|Liu, Kuang-Kai\|Chen, Ting-Hua\|Cheng, Hsiao-Chun\|Wang, Chi-Ching\|Li, Lily Yi\|Chen, Chinpiao\|Chao, Jui-I
PMID:	28852020

2500.
Journal:	Medicine (Baltimore). 2017 Sep;96(35):e7882.
Title:	Prognostic value of KRAS codon 13 gene mutation for overall survival in colorectal cancer: Direct and indirect comparison meta-analysis.
Author:	Kwak, Min Seob\|Cha, Jae Myung\|Yoon, Jin Young\|Jeon, Jung Won\|Shin, Hyun Phil\|Chang, Hye Jung\|Kim, Hyung Kyung\|Joo, Kwang Ro\|Lee, Joung Il
PMID:	28858102

2501.
Journal:	Br J Cancer. 2017 Oct 24;117(9):1286-1294.
Title:	Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations.
Author:	Gollins, Simon\|West, Nick\|Sebag-Montefiore, David\|Myint, Arthur Sun\|Saunders, Mark\|Susnerwala, Shabbir\|Quirke, Phil\|Essapen, Sharadah\|Samuel, Leslie\|Sizer, Bruce\|Worlding, Jane\|Southward, Katie\|Hemmings, Gemma\|Tinkler-Hundal, Emma\|Taylor, Morag\|Bottomley,
PMID:	28859058

2502.
Journal:	Mar Drugs. 2017 Sep 4;15(9). pii: md15090283.
Title:	Potential Application of Eicosapentaenoic Acid Monoacylglyceride in the Management of Colorectal Cancer.
Author:	Morin, Caroline\|Rodriguez, Enrique\|Blier, Pierre U\|Fortin, Samuel
PMID:	28869531

2503.
Journal:	Mol Imaging. 2017 Jan-Dec;16:1536012117729044.
Title:	Ex Vivo and In Vivo Noninvasive Imaging of Epidermal Growth Factor Receptor Inhibition on Colon Tumorigenesis Using Activatable Near-Infrared Fluorescent Probes.
Author:	Ding, Shengli\|Blue, Randall E\|Moorefield, Emily\|Yuan, Hong\|Lund, Pauline K
PMID:	28884622

2504.
Journal:	Yi Chuan. 2017 Jun 20;39(6):482-490.
Title:	Research progress on genetic heterogeneity between primary and paired metastatic colorectal cancer.
Author:	Lu, You-Wang\|Wang, Kun-Hua
PMID:	28903907

2505.
Journal:	Cell Death Discov. 2017 Sep 18;3:17063.
Title:	The lauric acid-activated signaling prompts apoptosis in cancer cells.
Author:	Lappano, Rosamaria\|Sebastiani, Anna\|Cirillo, Francesca\|Rigiracciolo, Damiano Cosimo\|Galli, Giulia Raffaella\|Curcio, Rosita\|Malaguarnera, Roberta\|Belfiore, Antonino\|Cappello, Anna Rita\|Maggiolini, Marcello
PMID:	28924490

2506.
Journal:	J Cancer. 2017 Aug 22;8(14):2713-2719.
Title:	The Impact of Cetuximab Plus AKT- or mTOR- Inhibitor in a Patient-Derived Colon Cancer Cell Model with Wild-Type RAS and PIK3CA Mutation.
Author:	Kim, Ju Sun\|Kim, Jung Eun\|Kim, Kyung\|Lee, Jeeyun\|Park, Joon Oh\|Lim, Ho Yeong\|Park, Young Suk\|Kang, Won Ki\|Kim, Seung Tae
PMID:	28928860

2507.
Journal:	Tumour Biol. 2017 Sep;39(9):1010428317724517.
Title:	EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features.
Author:	Alvarez, Karin\|Orellana, Paulina\|Villarroel, Cynthia\|Contreras, Luis\|Kawachi, Hiroshi\|Kobayashi, Maki\|Wielandt, Ana Maria\|De la Fuente, Marjorie\|Trivino, Juan Carlos\|Kronberg, Udo\|Carvallo, Pilar\|Lopez-Kostner, Francisco
PMID:	28936923

2508.
Journal:	Oncotarget. 2017 Jul 28;8(35):58133-58151.
Title:	Predictive clinical model of tumor response after chemoradiation in rectal cancer.
Author:	Santos, Marisa D\|Silva, Cristina\|Rocha, Anabela\|Nogueira, Carlos\|Castro-Pocas, Fernando\|Araujo, Antonio\|Matos, Eduarda\|Pereira, Carina\|Medeiros, Rui\|Lopes, Carlos
PMID:	28938543

2509.
Journal:	Cancer Res. 2017 Dec 1;77(23):6513-6523.
Title:	Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition.
Author:	Yaeger, Rona\|Yao, Zhan\|Hyman, David M\|Hechtman, Jaclyn F\|Vakiani, Efsevia\|Zhao, HuiYong\|Su, Wenjing\|Wang, Lu\|Joelson, Andrew\|Cercek, Andrea\|Baselga, Jose\|de Stanchina, Elisa\|Saltz, Leonard\|Berger, Michael F\|Solit, David B\|Rosen, Neal
PMID:	28951457

2510.
Journal:	Int J Environ Res Public Health. 2017 Sep 28;14(10). pii: ijerph14101146.
Title:	Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival.
Author:	Sharafeldin, Noha\|Slattery, Martha L\|Liu, Qi\|Franco-Villalobos, Conrado\|Caan, Bette J\|Potter, John D\|Yasui, Yutaka
PMID:	28956832

2511.
Journal:	Sci Data. 2017 Oct 3;4:170139.
Title:	High-throughput RNAi screen for essential genes and drug synergistic combinations in colorectal cancer.
Author:	Williams, Steven P\|Barthorpe, Andrew S\|Lightfoot, Howard\|Garnett, Mathew J\|McDermott, Ultan
PMID:	28972570

2512.
Journal:	Food Chem Toxicol. 2017 Dec;110:33-41.
Title:	Hijiki and sodium arsenite stimulate growth of human colorectal adenocarcinoma cells through ERK1/2 activation.
Author:	Cholpraipimolrat, Wanida\|Suriyo, Tawit\|Rangkadilok, Nuchanart\|Nookabkaew, Sumontha\|Satayavivad, Jutamaad
PMID:	28974440

2513.
Journal:	Am J Cancer Res. 2017 Sep 1;7(9):1978-1989. eCollection 2017.
Title:	KRAS mutation status is highly homogeneous between areas of the primary tumor and the corresponding metastasis of colorectal adenocarcinomas: one less problem in patient care.
Author:	Petaccia de Macedo, Mariana\|Melo, Fernanda M\|Ribeiro, Heber Salvador C\|Marques, Marcio C\|Kagohara, Luciane T\|Begnami, Maria Dirlei\|Neto, Julio C\|Ribeiro, Julia S\|Soares, Fernando A\|Carraro, Dirce M\|Cunha, Isabela W
PMID:	28979819

2514.
Journal:	PLoS One. 2017 Oct 5;12(10):e0175484.
Title:	Neutral evolution of drug resistant colorectal cancer cell populations is independent of their KRAS status.
Author:	Blagoev, Krastan B\|Wilkerson, Julia\|Burotto, Mauricio\|Kim, Chul\|Espinal-Dominguez, Edward\|Garcia-Alfonso, Pilar\|Alimchandani, Meghna\|Miettinen, Markku\|Blanco-Codesido, Montserrat\|Fojo, Tito
PMID:	28981524

2515.
Journal:	Br J Cancer. 2017 Dec 5;117(12):1819-1827.
Title:	Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.
Author:	Lievre, Astrid\|Ouine, Berengere\|Canet, Jim\|Cartier, Aurelie\|Amar, Yael\|Cacheux, Wulfran\|Mariani, Odette\|Guimbaud, Rosine\|Selves, Janick\|Lecomte, Thierry\|Guyetant, Serge\|Bieche, Ivan\|Berger, Frederique\|de Koning, Leanne
PMID:	29024937

2516.
Journal:	Oncotarget. 2017 Aug 11;8(39):66458-66466.
Title:	Targeted first-line therapies for advanced colorectal cancer: a Bayesian meta-analysis.
Author:	Ridouane, Yassine\|Lopes, Gilberto\|Ku, Geoffrey\|Masud, Hasan\|Haaland, Benjamin
PMID:	29029527

2517.
Journal:	Nat Med. 2017 Nov;23(11):1331-1341.
Title:	lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/beta-catenin signaling.
Author:	Lu, Yuanyuan\|Zhao, Xiaodi\|Liu, Qi\|Li, Cunxi\|Graves-Deal, Ramona\|Cao, Zheng\|Singh, Bhuminder\|Franklin, Jeffrey L\|Wang, Jing\|Hu, Huaying\|Wei, Tianying\|Yang, Mingli\|Yeatman, Timothy J\|Lee, Ethan\|Saito-Diaz, Kenyi\|Hinger, Scott\|Patton, James G\|Chung, Christin
PMID:	29035371

2518.
Journal:	Clin Lab. 2017 Oct 1;63(10):1731-1740.
Title:	Enhanced Specificity of BRAF V600E Genotyping Using Wild-Type Blocker Coupled with Internal Competitive Reference in a Single Tube.
Author:	Peng, Jia\|Wei, Kun\|Yu, Shu\|Yang, Xiang\|Zhao, Xiang\|Liu, Yu\|Zhu, Xiao-Yan\|Zhao, Na\|Huang, Qing\|Fu, Wei-Ling
PMID:	29035465

2519.
Journal:	Nat Commun. 2017 Oct 16;8(1):939.
Title:	PKCepsilon phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation.
Author:	Chen, Tao\|Li, Jingjie\|Xu, Meidong\|Zhao, Qin\|Hou, Yingyong\|Yao, Liqing\|Zhong, Yunshi\|Chou, Ping-Chieh\|Zhang, Wei\|Zhou, Pinghong\|Jiang, Yuhui
PMID:	29038521

2520.
Journal:	Gan To Kagaku Ryoho. 2017 Oct;44(10):947-949.
Title:	[Anti-EGFR Antibody Combination Chemotherapy Was Effective against Locally Advanced Ascending Colon Cancer as Well as a Recurrent Lesion - A Case Report].
Author:	Yamada, Yasufumi\|Yokomizo, Hajime\|Yano, Yuki\|Okayama, Sachiyo\|Satake, Masaya\|Ida, Arika\|Usui, Takebumi\|Yamaguchi, Kentaro\|Shiozawa, Shunichi\|Yoshimatsu, Kazuhiko\|Shimakawa, Takeshi\|Katsube, Takao\|Naritaka, Yoshihiko\|Kato, Hiroyuki
PMID:	29066705

2521.
Journal:	Oncotarget. 2017 Aug 7;8(42):72633-72651.
Title:	RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR.
Author:	Li, Haiping\|Al-Japairai, K\|Tao, Yong\|Xiang, Zheng
PMID:	29069815

2522.
Journal:	Ann Surg Treat Res. 2017 Oct;93(4):173-180.
Title:	Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy.
Author:	Jung, Joohee\|Kim, Jisup\|Lim, Hyun Kyung\|Kim, Kyoung Mee\|Lee, Yun Sun\|Park, Joon Seong\|Yoon, Dong Sup
PMID:	29094026

2523.
Journal:	Oncotarget. 2017 May 26;8(44):77928-77941.
Title:	Meta-analysis of the mutational status of circulation tumor cells and paired primary tumor tissues from colorectal cancer patients.
Author:	Liu, Yong\|Meucci, Stefano\|Sheng, Liming\|Keilholz, Ulrich
PMID:	29100436

2524.
Journal:	BMC Cancer. 2017 Nov 7;17(1):723.
Title:	microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer.
Author:	Takahashi, Hidekazu\|Takahashi, Masanobu\|Ohnuma, Shinobu\|Unno, Michiaki\|Yoshino, Yuki\|Ouchi, Kota\|Takahashi, Shin\|Yamada, Yasuhide\|Shimodaira, Hideki\|Ishioka, Chikashi
PMID:	29115941

2525.
Journal:	Cancer Med. 2017 Dec;6(12):2972-2983.
Title:	In vivo imaging xenograft models for the evaluation of anti-brain tumor efficacy of targeted drugs.
Author:	Kita, Kenji\|Arai, Sachiko\|Nishiyama, Akihiro\|Taniguchi, Hirokazu\|Fukuda, Koji\|Wang, Rong\|Yamada, Tadaaki\|Takeuchi, Shinji\|Tange, Shoichiro\|Tajima, Atsushi\|Nakada, Mitsutoshi\|Yasumoto, Kazuo\|Motoo, Yoshiharu\|Murakami, Takashi\|Yano, Seiji
PMID:	29125233

2526.
Journal:	Oncotarget. 2017 Aug 8;8(48):83860-83871.
Title:	Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics.
Author:	Jin, Choong Eun\|Yeom, Seung-Seop\|Koo, Bonhan\|Lee, Tae Yoon\|Lee, Jeong Hoon\|Shin, Yong\|Lim, Seok-Byung
PMID:	29137388

2527.
Journal:	Onco Targets Ther. 2017 Nov 3;10:5281-5288.
Title:	PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells.
Author:	Guo, Lingchuan\|Huang, Shan\|Wang, Xinwei
PMID:	29138581

2528.
Journal:	Oncotarget. 2017 Sep 23;8(50):87718-87736.
Title:	HDAC-4 regulates claudin-2 expression in EGFR-ERK1/2 dependent manner to regulate colonic epithelial cell differentiation.
Author:	Ahmad, Rizwan\|Kumar, Balawant\|Pan, Kaichao\|Dhawan, Punita\|Singh, Amar B
PMID:	29152115

2529.
Journal:	Oncotarget. 2017 Sep 21;8(49):86356-86368.
Title:	Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers.
Author:	Salem, Mohamed E\|Weinberg, Benjamin A\|Xiu, Joanne\|El-Deiry, Wafik S\|Hwang, Jimmy J\|Gatalica, Zoran\|Philip, Philip A\|Shields, Anthony F\|Lenz, Heinz-Josef\|Marshall, John L
PMID:	29156800

2530.
Journal:	Oncogenesis. 2017 Dec 4;6(11):399.
Title:	MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9.
Author:	Vychytilova-Faltejskova, Petra\|Merhautova, Jana\|Machackova, Tana\|Gutierrez-Garcia, Irene\|Garcia-Solano, Jose\|Radova, Lenka\|Brchnelova, Dominika\|Slaba, Katerina\|Svoboda, Marek\|Halamkova, Jana\|Demlova, Regina\|Kiss, Igor\|Vyzula, Rostislav\|Conesa-Zamora, Pabl
PMID:	29199273

2531.
Journal:	Heliyon. 2017 Nov 21;3(11):e00448.
Title:	KRAS biomarker testing disparities in colorectal cancer patients in New Mexico.
Author:	Greenbaum, Alissa\|Wiggins, Charles\|Meisner, Angela Lw\|Rojo, Manuel\|Kinney, Anita Y\|Rajput, Ashwani
PMID:	29202108

2532.
Journal:	Oncotarget. 2017 Sep 27;8(55):93856-93866.
Title:	Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: a post-hoc analysis of the New EPOC trial.
Author:	Pugh, Sian\|Thiebaut, Raphaele\|Bridgewater, John\|Grisoni, Marie-Lise\|Moutasim, Karwan\|Rousseau, Francis\|Thomas, Gareth J\|Griffiths, Gareth\|Liebaert, Francois\|Primrose, John\|Laurent-Puig, Pierre
PMID:	29212194

2533.
Journal:	Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Dec 18;49(6):931-936.
Title:	[Mechanism of cross talk between tissue factor/active coagulation factor VII and epidermal growth factor receptor signalings in colon cancer cells in culture].
Author:	Chen, H K\|Dai, Y\|Wu, T\|Wang, X\|Wan, Y L\|Tang, J Q
PMID:	29263461

2534.
Journal:	Molecules. 2017 Dec 27;23(1). pii: molecules23010048.
Title:	Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
Author:	Alswah, Mohamed\|Bayoumi, Ashraf H\|Elgamal, Kamal\|Elmorsy, Ahmed\|Ihmaid, Saleh\|Ahmed, Hany E A
PMID:	29280968

2535.
Journal:	Oncotarget. 2017 Sep 23;8(62):105061-105071.
Title:	AIO LQ-0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumab-mediated skin toxicity in patients with metastatic colorectal cancer.
Author:	Kripp, Melanie\|Prasnikar, Nicole\|Vehling-Kaiser, Ursula\|Quidde, Julia\|Al-Batran, Salah-Eddin\|Stein, Alexander\|Neben, Kai\|Hannig, Carla Verena\|Tessen, Hans Werner\|Trarbach, Tanja\|Hinke, Axel\|Hofheinz, Ralf-Dieter
PMID:	29285233

2536.
Journal:	Oncotarget. 2017 Sep 27;8(62):105072-105080.
Title:	Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.
Author:	Hou, Helei\|Liu, Dong\|Zhang, Chuantao\|Jiang, Yanxia\|Lu, Guifang\|Zhou, Na\|Yang, Xiaonan\|Zhang, Xiaoping\|Li, Zhuokun\|Zhu, Hongmei\|Qian, Zhaoyang\|Zhang, Xiaochun
PMID:	29285234

2537.
Journal:	J Gastrointest Oncol. 2017 Dec;8(6):980-984.
Title:	The correlations between serum amphiregulin and other clinicopathological factors in colorectal cancer.
Author:	Chayangsu, Chawalit\|Khunsri, Siriporn\|Sriuranpong, Virote\|Tanasanvimon, Suebpong
PMID:	29299357

2538.
Journal:	Oncotarget. 2017 Nov 26;8(65):108303-108315.
Title:	Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the Apc(Min) model of colorectal cancer.
Author:	Dombernowsky, Sarah L\|Schwarz, Jeanette\|Samsoe-Petersen, Jacob\|Albrechtsen, Reidar\|Jensen, Kim B\|Thomas, Gary\|Kveiborg, Marie
PMID:	29312533

2539.
Journal:	Oncotarget. 2016 Aug 19;8(65):108463-108479.
Title:	Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers.
Author:	Bon, Giulia\|Loria, Rossella\|Amoreo, Carla Azzurra\|Verdina, Alessandra\|Sperduti, Isabella\|Mastrofrancesco, Arianna\|Soddu, Silvia\|Diodoro, Maria Grazia\|Mottolese, Marcella\|Todaro, Matilde\|Stassi, Giorgio\|Milella, Michele\|De Maria, Ruggero\|Falcioni, Rita
PMID:	29312543

2540.
Journal:	Case Rep Nephrol. 2017;2017:7964015.
Title:	Cetuximab-Associated Crescentic Diffuse Proliferative Glomerulonephritis.
Author:	Manthri, Sukesh\|Bandaru, Sindhura\|Chang, Anthony\|Hudali, Tamer
PMID:	29348949

2541.
Journal:	Gastroenterol Hepatol Bed Bench. 2017 Fall;10(4):295-302.
Title:	Network analysis of common genes related to esophageal, gastric, and colon cancers.
Author:	Vaseghi Maghvan, Padina\|Rezaei-Tavirani, Mostafa\|Zali, Hakimeh\|Nikzamir, Abdolrahim\|Abdi, Saeed\|Khodadoostan, Mahsa\|Asadzadeh-Aghdaei, Hamid
PMID:	29379595

2542.
Journal:	Oncotarget. 2017 Dec 9;8(70):114663-114676.
Title:	EGFR expression in patients with stage III colorectal cancer after adjuvant chemotherapy and on cancer cell function.
Author:	Huang, Ching-Wen\|Chen, Yi-Ting\|Tsai, Hsiang-Lin\|Yeh, Yung-Sung\|Su, Wei-Chih\|Ma, Cheng-Jen\|Tsai, Tsen-Ni\|Wang, Jaw-Yuan
PMID:	29383110

2543.
Journal:	Gan To Kagaku Ryoho. 2017 Nov;44(12):1420-1422.
Title:	[Case Report of Long-Term Survival for Stage IV Advanced Sigmoid Colon Cancer with Para-Aortic Nodes by R0 Resection and Chemotherapy].
Author:	Akai, Masaaki\|Otsuka, Shinya\|Yasui, Yuichi\|Isoda, Kenta\|Hamano, Ryousuke\|Tokunaga, Naoyuki\|Takahashi, Kenji\|Miyaso, Hideaki\|Tsunemitsu, Yousuke\|Iwakawa, Kazuhide\|Inagaki, Masaru\|Iwagaki, Hiromi
PMID:	29394654

2544.
Journal:	Am J Clin Oncol. 2018 Jun;41(6):613-618.
Title:	Molecular Predictors of Response to Neoadjuvant Chemoradiation for Rectal Cancer.
Author:	Kundel, Yulia\|Nasser, Nicola J\|Rath-Wolfson, Lea\|Purim, Ofer\|Yanichkin, Natalia\|Brenner, Ronen\|Zehavi, Tanya\|Nardi, Yuval\|Fenig, Eyal\|Sulkes, Aaron\|Brenner, Baruch
PMID:	27740975

2545.
Journal:	Gut. 2018 Mar;67(3):473-484.
Title:	Protein and glycomic plasma markers for early detection of adenoma and colon cancer.
Author:	Rho, Jung-Hyun\|Ladd, Jon J\|Li, Christopher I\|Potter, John D\|Zhang, Yuzheng\|Shelley, David\|Shibata, David\|Coppola, Domenico\|Yamada, Hiroyuki\|Toyoda, Hidenori\|Tada, Toshifumi\|Kumada, Takashi\|Brenner, Dean E\|Hanash, Samir M\|Lampe, Paul D
PMID:	27821646

2546.
Journal:	J Gastrointest Cancer. 2018 Jun;49(2):124-131.
Title:	Clinicopathological Associations of K-RAS and N-RAS Mutations in Indonesian Colorectal Cancer Cohort.
Author:	Levi, Michael\|Prayogi, Gintang\|Sastranagara, Farid\|Sudianto, Edi\|Widjajahakim, Grace\|Gani, Winiarti\|Mahanadi, Albert\|Agnes, Jocelyn\|Khairunisa, Bela Haifa\|Utomo, Ahmad R
PMID:	28044264

2547.
Journal:	Curr Cancer Drug Targets. 2018;18(5):430-441.
Title:	The Role of Target Therapy in the Treatment of Gastrointestinal Noncolorectal Cancers: Clinical Impact and Cost Consideration.
Author:	Berretta, Massimiliano\|Romano, Carmela\|Di Francia, Raffaele\|De Diviitis, Chiara\|Canzonieri, Vincenzo\|Caraglia, Michele\|Facchini, Gaetano\|Nasti, Guglielmo
PMID:	28183250

2548.
Journal:	Curr Cancer Drug Targets. 2018;18(5):421-429.
Title:	Metastatic Colorectal Cancer: Role of Target Therapies and Future Perspectives.
Author:	Nappi, Anna\|Berretta, Massimiliano\|Romano, Carmela\|Tafuto, Salvatore\|Cassata, Antonino\|Casaretti, Rossana\|Silvestro, Lucrezia\|Divitiis, Chiara De\|Alessandrini, Lara\|Fiorica, Francesco\|Ottaiano, Alessandro\|Nasti, Guglielmo
PMID:	28183254

2549.
Journal:	J Cell Physiol. 2018 Mar;233(3):2058-2066.
Title:	Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer.
Author:	Bahrami, Afsane\|Hassanian, Seyed Mahdi\|ShahidSales, Soodabeh\|Farjami, Zahra\|Hasanzadeh, Malihe\|Anvari, Kazem\|Aledavood, Amir\|Maftouh, Mina\|Ferns, Gordon A\|Khazaei, Majid\|Avan, Amir
PMID:	28262927

2550.
Journal:	Curr Cancer Drug Targets. 2018;18(3):278-286.
Title:	Effects of PHA-665752 and Cetuximab Combination Treatment on In Vitro and Murine Xenograft Growth of Human Colorectal Cancer Cells with KRAS or BRAF Mutations.
Author:	Jia, Yi-Tao\|Yang, Dong-Hai\|Zhao, Zhaolong\|Bi, Xiao-Hui\|Han, Wei-Hua\|Feng, Bo\|Zhi, Jie\|Gu, Bin\|Duan, Zhihui\|Wu, Jian-Hua\|Ju, Ying-Chao\|Wang, Ming-Xia\|Li, Zhong-Xin
PMID:	28359236

2551.
Journal:	Anticancer Agents Med Chem. 2018 Feb 7;17(14):1931-1941.
Title:	Synthesis, Characterization of 4-Anilino-6,7-Dimethoxy Quinazoline Derivatives as Potential Anti-Angiogenic Agents.
Author:	Devegowda, Preethi Saligrama\|Balaji, Kyathegowdanadoddi Srinivasa\|Prasanna, Doddakunche Shivaramu\|Swaroop, Toreshettahally Ramesh\|Kameshwar, Vivek Hamse\|Jayarama, Shankar\|Siddalingaiah, Lokesh\|Rangappa, Kanchugarakoppal Subbegowda
PMID:	28403784

2552.
Journal:	J Cell Physiol. 2018 Mar;233(3):2162-2169.
Title:	The therapeutic potential of targeting the BRAF mutation in patients with colorectal cancer.
Author:	Bahrami, Afsane\|Hesari, AmirReza\|Khazaei, Majid\|Hassanian, Seyed Mahdi\|Ferns, Gordon A\|Avan, Amir
PMID:	28407239

2553.
Journal:	J Gastrointest Cancer. 2018 Sep;49(3):283-287.
Title:	Left Versus Right: Does Location Matter for Refractory Metastatic Colorectal Cancer Patients in Phase 1 Clinical Trials?
Author:	Arora, Sukeshi Patel\|Ketchum, Norma S\|Michalek, Joel\|Gelfond, Jonathon\|Mahalingam, Devalingam
PMID:	28432610

2554.
Journal:	Breast Cancer. 2018 Jan;25(1):74-80.
Title:	The role of PRMT1 in EGFR methylation and signaling in MDA-MB-468 triple-negative breast cancer cells.
Author:	Nakai, Katsuya\|Xia, Weiya\|Liao, Hsin-Wei\|Saito, Mitsue\|Hung, Mien-Chie\|Yamaguchi, Hirohito
PMID:	28643125

2555.
Journal:	Rev Physiol Biochem Pharmacol. 2018;174:1-23.
Title:	Ezrin Orchestrates Signal Transduction in Airway Cells.
Author:	Yin, Lei-Miao\|Duan, Ting-Ting\|Ulloa, Luis\|Yang, Yong-Qing
PMID:	28702704

2556.
Journal:	Surg Endosc. 2018 Mar;32(3):1533-1539.
Title:	Simvastatin enhances radiation sensitivity of colorectal cancer cells.
Author:	Karagkounis, Georgios\|DeVecchio, Jennifer\|Ferrandon, Sylvain\|Kalady, Matthew F
PMID:	28916945

2557.
Journal:	Ann Oncol. 2018 Jan 1;29(1):112-118.
Title:	RAS testing of liquid biopsy correlates with the outcome of metastatic colorectal cancer patients treated with first-line FOLFIRI plus cetuximab in the CAPRI-GOIM trial.
Author:	Normanno, N\|Esposito Abate, R\|Lambiase, M\|Forgione, L\|Cardone, C\|Iannaccone, A\|Sacco, A\|Rachiglio, A M\|Martinelli, E\|Rizzi, D\|Pisconti, S\|Biglietto, M\|Bordonaro, R\|Troiani, T\|Latiano, T P\|Giuliani, F\|Leo, S\|Rinaldi, A\|Maiello, E\|Ciardiello, F
PMID:	28950295

2558.
Journal:	Clin Cancer Res. 2018 Feb 15;24(4):807-820.
Title:	A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem-Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy.
Author:	Luraghi, Paolo\|Bigatto, Viola\|Cipriano, Elia\|Reato, Gigliola\|Orzan, Francesca\|Sassi, Francesco\|De Bacco, Francesca\|Isella, Claudio\|Bellomo, Sara E\|Medico, Enzo\|Comoglio, Paolo M\|Bertotti, Andrea\|Trusolino, Livio\|Boccaccio, Carla
PMID:	28974546

2559.
Journal:	Food Chem. 2018 Mar 1;242:378-388.
Title:	Comparison of the effect of chemical composition of anthocyanin-rich plant extracts on colon cancer cell proliferation and their potential mechanism of action using in vitro, in silico, and biochemical assays.
Author:	Mazewski, Candice\|Liang, Katie\|Gonzalez de Mejia, Elvira
PMID:	29037704

2560.
Journal:	Chem Biol Drug Des. 2018 Feb;91(2):605-619.
Title:	Peptide ligands for targeting the extracellular domain of EGFR: Comparison between linear and cyclic peptides.
Author:	Williams, Tyrslai M\|Sable, Rushikesh\|Singh, Sitanshu\|Vicente, Maria Graca H\|Jois, Seetharama D
PMID:	29052959

2561.
Journal:	J Cell Biochem. 2018 Mar;119(3):2864-2874.
Title:	HOXA3 promotes tumor growth of human colon cancer through activating EGFR/Ras/Raf/MEK/ERK signaling pathway.
Author:	Zhang, Xianxiang\|Liu, Guangwei\|Ding, Lei\|Jiang, Tao\|Shao, Shihong\|Gao, Yuan\|Lu, Yun
PMID:	29073728

2562.
Journal:	JAMA Oncol. 2018 Apr 1;4(4):564-568.
Title:	Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer.
Author:	Seligmann, Jenny F\|Hatch, Ace J\|Richman, Susan D\|Elliott, Faye\|Jacobs, Bart\|Brown, Sarah\|Hurwitz, Herbert\|Barrett, Jennifer H\|Quirke, Philip\|Nixon, Andrew B\|Seymour, Matthew T
PMID:	29075780

2563.
Journal:	Stem Cells. 2018 Feb;36(2):252-264.
Title:	Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration.
Author:	Piryani, Sadhna O\|Kam, Angel Y F\|Kliassov, Evelyna G\|Chen, Benny J\|Spector, Neil L\|Chute, John P\|Hsu, David S\|Chao, Nelson J\|Doan, Phuong L
PMID:	29086459

2564.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):e69-e76.
Title:	Treatment and Survival Outcome of BRAF-Mutated Metastatic Colorectal Cancer: A Retrospective Matched Case-Control Study.
Author:	Kayhanian, Hamzeh\|Goode, Emily\|Sclafani, Francesco\|Ang, Joo Ern\|Gerlinger, Marco\|Gonzalez de Castro, David\|Shepherd, Scott\|Peckitt, Clare\|Rao, Sheela\|Watkins, David\|Chau, Ian\|Cunningham, David\|Starling, Naureen
PMID:	29129559

2565.
Journal:	Br J Cancer. 2018 Feb 20;118(4):558-565.
Title:	LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity.
Author:	Morgan, R G\|Mortensson, E\|Legge, D N\|Gupta, B\|Collard, T J\|Greenhough, A\|Williams, A C
PMID:	29149105

2566.
Journal:	Biomed Pharmacother. 2018 Jan;97:1319-1330.
Title:	MicroRNAs as novel biomarkers for colorectal cancer: New outlooks.
Author:	Shirafkan, Naghmeh\|Mansoori, Behzad\|Mohammadi, Ali\|Shomali, Navid\|Ghasbi, Mehri\|Baradaran, Behzad
PMID:	29156521

2567.
Journal:	Mol Cancer Ther. 2018 Feb;17(2):521-531.
Title:	Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance.
Author:	Bagchi, Atrish\|Haidar, Jaafar N\|Eastman, Scott W\|Vieth, Michal\|Topper, Michael\|Iacolina, Michelle D\|Walker, Jason M\|Forest, Amelie\|Shen, Yang\|Novosiadly, Ruslan D\|Ferguson, Kathryn M
PMID:	29158469

2568.
Journal:	Mol Cancer Ther. 2018 Apr;17(4):806-813.
Title:	Wnt/beta-Catenin Pathway Activation Mediates Adaptive Resistance to BRAF Inhibition in Colorectal Cancer.
Author:	Chen, Guangming\|Gao, Chenxi\|Gao, Xuan\|Zhang, Dennis Han\|Kuan, Shih-Fan\|Burns, Timothy F\|Hu, Jing
PMID:	29167314

2569.
Journal:	Eur J Surg Oncol. 2018 Jan;44(1):115-121.
Title:	Exome sequencing of synchronously resected primary colorectal tumours and colorectal liver metastases to inform oncosurgical management.
Author:	Sutton, P A\|Jithesh, P V\|Jones, R P\|Evans, J P\|Vimalachandran, D\|Malik, H Z\|Park, B K\|Goldring, C E\|Palmer, D H\|Kitteringham, N R
PMID:	29174709

2570.
Journal:	Cancer Discov. 2018 Feb;8(2):164-173.
Title:	Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer.
Author:	Strickler, John H\|Loree, Jonathan M\|Ahronian, Leanne G\|Parikh, Aparna R\|Niedzwiecki, Donna\|Pereira, Allan Andresson Lima\|McKinney, Matthew\|Korn, W Michael\|Atreya, Chloe E\|Banks, Kimberly C\|Nagy, Rebecca J\|Meric-Bernstam, Funda\|Lanman, Richard B\|Talasaz, A
PMID:	29196463

2571.
Journal:	J Gastrointest Surg. 2018 Mar;22(3):523-528.
Title:	Does the Addition of Biologic Agents to Chemotherapy in Patients with Unresectable Colorectal Cancer Metastases Result in a Higher Proportion of Patients Undergoing Resection? A Systematic Review and Meta-analysis.
Author:	Bogach, Jessica\|Levine, Oren\|Parpia, Sameer\|Valencia, Marlie\|Ruo, Leyo\|Serrano, Pablo
PMID:	29204907

2572.
Journal:	Mol Cancer Res. 2018 Mar;16(3):543-553.
Title:	TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting beta-CATENIN and AKT Signaling in Colorectal Cancer.
Author:	Solberg, Nina T\|Waaler, Jo\|Lund, Kaja\|Mygland, Line\|Olsen, Petter A\|Krauss, Stefan
PMID:	29222171

2573.
Journal:	Clin Cancer Res. 2018 Feb 15;24(4):794-806.
Title:	Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies.
Author:	Sveen, Anita\|Bruun, Jarle\|Eide, Peter W\|Eilertsen, Ina A\|Ramirez, Lorena\|Murumagi, Astrid\|Arjama, Mariliina\|Danielsen, Stine A\|Kryeziu, Kushtrim\|Elez, Elena\|Tabernero, Josep\|Guinney, Justin\|Palmer, Hector G\|Nesbakken, Arild\|Kallioniemi, Olli\|Dienstmann, R
PMID:	29242316

2574.
Journal:	Lancet Gastroenterol Hepatol. 2018 Mar;3(3):162-171.
Title:	Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2-3 randomised trial.
Author:	Adams, Richard\|Brown, Ewan\|Brown, Louise\|Butler, Rachel\|Falk, Stephen\|Fisher, David\|Kaplan, Richard\|Quirke, Phil\|Richman, Susan\|Samuel, Leslie\|Seligmann, Jenny\|Seymour, Matt\|Shiu, Kai Keen\|Wasan, Harpreet\|Wilson, Richard\|Maughan, Tim
PMID:	29254887

2575.
Journal:	Oncologist. 2018 Mar;23(3):277-e26.
Title:	Phase II Study of Panitumumab in RAS Wild-Type Metastatic Adenocarcinoma of Small Bowel or Ampulla of Vater.
Author:	Gulhati, Pat\|Raghav, Kanwal\|Shroff, Rachna\|Varadhachary, Gauri\|Javle, Milind\|Qiao, Wei\|Wang, Huamin\|Morris, Jeffrey\|Wolff, Robert\|Overman, Michael J
PMID:	29259073

2576.
Journal:	Crit Rev Oncol Hematol. 2018 Jan;121:1-10.
Title:	The predictive value of primary tumor location in patients with metastatic colorectal cancer: A systematic review.
Author:	Boeckx, Nele\|Janssens, Katleen\|Van Camp, Guy\|Rasschaert, Marika\|Papadimitriou, Konstantinos\|Peeters, Marc\|Op de Beeck, Ken
PMID:	29279095

2577.
Journal:	Genome Med. 2018 Jan 4;10(1):2.
Title:	Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.
Author:	Kundu, Snehangshu\|Ali, Muhammad Akhtar\|Handin, Niklas\|Padhan, Narendra\|Larsson, Jimmy\|Karoutsou, Maria\|Ban, Kenneth\|Wisniewski, Jacek R\|Artursson, Per\|He, Liqun\|Hellstrom, Mats\|Sjoblom, Tobias
PMID:	29301589

2578.
Journal:	Sensors (Basel). 2018 Jan 5;18(1). pii: s18010131.
Title:	Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform.
Author:	Guarnaccia, Maria\|Iemmolo, Rosario\|San Biagio, Floriana\|Alessi, Enrico\|Cavallaro, Sebastiano
PMID:	29304017

2579.
Journal:	Adv Clin Chem. 2018;83:53-72.
Title:	Locked Nucleic Acid Technology for Highly Sensitive Detection of Somatic Mutations in Cancer.
Author:	Ishige, Takayuki\|Itoga, Sakae\|Matsushita, Kazuyuki
PMID:	29304903

2580.
Journal:	Oncoimmunology. 2017 Nov 13;7(2):e1393597.
Title:	Enhancement of antibody-dependent cellular cytotoxicity of cetuximab by a chimeric protein encompassing interleukin-15.
Author:	Ochoa, Maria Carmen\|Minute, Luna\|Lopez, Ascension\|Perez-Ruiz, Elisabeth\|Gomar, Celia\|Vasquez, Marcos\|Inoges, Susana\|Etxeberria, Inaki\|Rodriguez, Inmaculada\|Garasa, Saray\|Mayer, Jan-Peter Andreas\|Wirtz, Peter\|Melero, Ignacio\|Berraondo, Pedro
PMID:	29308327

2581.
Journal:	Oncogene. 2018 Mar;37(12):1576-1593.
Title:	BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.
Author:	Herr, Ricarda\|Halbach, Sebastian\|Heizmann, Miriam\|Busch, Hauke\|Boerries, Melanie\|Brummer, Tilman
PMID:	29326440

2582.
Journal:	Mod Pathol. 2018 May;31(5):829-839.
Title:	Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix.
Author:	Jesinghaus, Moritz\|Konukiewitz, Bjorn\|Foersch, Sebastian\|Stenzinger, Albrecht\|Steiger, Katja\|Muckenhuber, Alexander\|Gross, Claudia\|Mollenhauer, Martin\|Roth, Wilfried\|Detlefsen, Sonke\|Weichert, Wilko\|Kloppel, Gunter\|Pfarr, Nicole\|Schlitter, Anna Melissa
PMID:	29327707

2583.
Journal:	Virchows Arch. 2018 May;472(5):717-725.
Title:	RAS testing for colorectal cancer patients is reliable in European laboratories that pass external quality assessment.
Author:	Tack, V\|Ligtenberg, M J L\|Siebers, A G\|Rombout, P D M\|Dabir, P D\|Weren, R D A\|van Krieken, J H J M\|Dequeker, E M C
PMID:	29333594

2584.
Journal:	Exp Mol Pathol. 2018 Feb;104(1):76-81.
Title:	Intratumoral morphological heterogeneity can be an indicator of genetic heterogeneity in colorectal cancer.
Author:	Buttner, Juliane\|Johrens, Korinna\|Klauschen, Frederick\|Hummel, Michael\|Lenze, Dido\|Saeger, Wolfgang\|Lehmann, Annika
PMID:	29337243

2585.
Journal:	Cancer. 2018 Apr 1;124(7):1358-1373.
Title:	Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.
Author:	Ross, Jeffrey S\|Fakih, Marwan\|Ali, Siraj M\|Elvin, Julia A\|Schrock, Alexa B\|Suh, James\|Vergilio, Jo-Anne\|Ramkissoon, Shakti\|Severson, Eric\|Daniel, Sugganth\|Fabrizio, David\|Frampton, Garrett\|Sun, James\|Miller, Vincent A\|Stephens, Philip J\|Gay, Laurie M
PMID:	29338072

2586.
Journal:	Bioconjug Chem. 2018 Feb 21;29(2):250-254.
Title:	Pretargeted Immuno-PET Based on Bioorthogonal Chemistry for Imaging EGFR Positive Colorectal Cancer.
Author:	Shi, Xudong\|Gao, Kai\|Huang, Hao\|Gao, Ran
PMID:	29338219

2587.
Journal:	Med Sci Monit. 2018 Jan 17;24:332-341.
Title:	Caveolin-1 Inhibits Proliferation, Migration, and Invasion of Human Colorectal Cancer Cells by Suppressing Phosphorylation of Epidermal Growth Factor Receptor.
Author:	Yang, Juanli\|Zhu, Tienian\|Zhao, Ruijing\|Gao, Dongmei\|Cui, Yujie\|Wang, Kun\|Guo, Yanli
PMID:	29339715

2588.
Journal:	J Cancer. 2018 Jan 1;9(2):358-366.
Title:	Clinical Significance of Glycoprotein Non-metastatic B and Its Association with EGFR/HER2 in Gastrointestinal Cancer.
Author:	Tajima, Jesse Yu\|Futamura, Manabu\|Gaowa, Siqin\|Mori, Ryutaro\|Tanahashi, Toshiyuki\|Tanaka, Yoshihiro\|Matsuhashi, Nobuhisa\|Takahashi, Takao\|Yamaguchi, Kazuya\|Miyazaki, Tatsuhiko\|Yoshida, Kazuhiro
PMID:	29344282

2589.
Journal:	Curr Mol Pharmacol. 2018;11(3):184-190.
Title:	Targeting M3 Muscarinic Receptors for Colon Cancer Therapy.
Author:	Felton, Jessica\|Hu, Shien\|Raufman, Jean-Pierre
PMID:	29357811

2590.
Journal:	Cancer Res Treat. 2018 Jan 17. pii: crt.2017.487.
Title:	Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer.
Author:	Yun, Sumi\|Kwak, Yoonjin\|Nam, Soo Kyung\|Seo, An Na\|Oh, Heung-Kwon\|Kim, Duck-Woo\|Kang, Sung-Bum\|Lee, Hye Seung
PMID:	29361822

2591.
Journal:	Gan To Kagaku Ryoho. 2018 Jan;45(1):175-177.
Title:	[A Case of Rectal Cancer with Multiple Endocrine Neoplasia Type 2].
Author:	Mori, Ryota\|Murata, Kohei\|Kagawa, Yoshinori\|Nose, Yohei\|Kawai, Kenji\|Sakamoto, Takuya\|Naito, Atsushi\|Murakami, Kohei\|Katsura, Yoshiteru\|Ohmura, Yoshiaki\|Masuzawa, Toru\|Takeno, Atsushi\|Takeda, Yutaka
PMID:	29362346

2592.
Journal:	Int J Cancer. 2018 Jun 15;142(12):2578-2588.
Title:	Inhibition of SLC1A5 sensitizes colorectal cancer to cetuximab.
Author:	Ma, Huanrong\|Wu, Zhenzhen\|Peng, Jianjun\|Li, Yang\|Huang, Hongxiang\|Liao, Yi\|Zhou, Minyu\|Sun, Li\|Huang, Na\|Shi, Min\|Bin, Jianping\|Liao, Yulin\|Rao, Jinjun\|Wang, Lin\|Liao, Wangjun
PMID:	29363109

2593.
Journal:	Transl Oncol. 2018 Apr;11(2):213-220.
Title:	Significance of Liquid Biopsy for Monitoring and Therapy Decision of Colorectal Cancer.
Author:	Klein-Scory, Susanne\|Maslova, Marina\|Pohl, Michael\|Eilert-Micus, Christina\|Schroers, Roland\|Schmiegel, Wolff\|Baraniskin, Alexander
PMID:	29367069

2594.
Journal:	ACS Appl Mater Interfaces. 2018 Feb 21;10(7):6096-6106.
Title:	Panitumumab-Conjugated and Platinum-Cored pH-Sensitive Apoferritin Nanocages for Colorectal Cancer-Targeted Therapy.
Author:	Lin, Chun-Yen\|Yang, Shu-Jyuan\|Peng, Cheng-Liang\|Shieh, Ming-Jium
PMID:	29368506

2595.
Journal:	J Clin Lab Anal. 2018 Jun;32(5):e22391.
Title:	A novel cell line generated using the CRISPR/Cas9 technology as universal quality control material for KRAS G12V mutation testing.
Author:	Jia, Shiyu\|Zhang, Rui\|Lin, Guigao\|Peng, Rongxue\|Gao, Peng\|Han, Yanxi\|Fu, Yu\|Ding, Jiansheng\|Wu, Qisheng\|Zhang, Kuo\|Xie, Jiehong\|Li, Jinming
PMID:	29380513

2596.
Journal:	J Gastrointest Cancer. 2018 Feb 1. pii: 10.1007/s12029-018-0062-y.
Title:	Clinical Impact of PI3K/BRAF Mutations in RAS Wild Metastatic Colorectal Cancer: Meta-analysis Results.
Author:	Mohamed, Amr\|Twardy, Brandon\|AbdAllah, Nadine\|Akhras, Alaa\|Ismail, Hibah\|Zordok, Magdi\|Schrapp, Kelly\|Attumi, Taraq\|Tesfaye, Anteneh\|El-Rayes, Bassel
PMID:	29388061

2597.
Journal:	World J Gastroenterol. 2018 Jan 21;24(3):351-359.
Title:	Epidermal growth factor receptor-targeted immune magnetic liposomes capture circulating colorectal tumor cells efficiently.
Author:	Kuai, Jing-Hua\|Wang, Qing\|Zhang, Ai-Jun\|Zhang, Jing-Yu\|Chen, Zheng-Feng\|Wu, Kang-Kang\|Hu, Xiao-Zhen
PMID:	29391757

2598.
Journal:	Onco Targets Ther. 2018 Jan 22;11:465-471.
Title:	Subsequent anti-VEGF therapy after first-line anti-EGFR therapy improved overall survival of patients with metastatic colorectal cancer.
Author:	Qiu, Tianzhu\|Chen, Wensen\|Li, Ping\|Sun, Jing\|Gu, Yanhong\|Chen, Xiaofeng
PMID:	29403291

2599.
Journal:	Hum Pathol. 2018 Jul;77:1-10.
Title:	The importance of EGFR as a biomarker in molecular apocrine breast cancer.
Author:	Liu, Xiaozhen\|Feng, Changyun\|Liu, Junjun\|Liu, Jian\|Li, Congying\|Xu, Cong\|Niu, Yun
PMID:	29409930

2600.
Journal:	Ann Diagn Pathol. 2018 Feb;32:41-46.
Title:	Colorectal signet ring cell carcinoma: Influence of EGFR, E-cadherin and MMP-13 expression on clinicopathological features and prognosis.
Author:	Foda, Abd Al-Rahman Mohammad\|Aziz, Azza Abdel\|Mohamed, Mie Ali
PMID:	29414397

2601.
Journal:	Pathobiology. 2018;85(1-2):72-84.
Title:	Tumor Heterogeneity in Colorectal Cancer: What Do We Know So Far?
Author:	Sagaert, Xavier\|Vanstapel, Arno\|Verbeek, Sanne
PMID:	29414818

2602.
Journal:	Cancer Discov. 2018 Apr;8(4):417-427.
Title:	Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAF(V600E) Colorectal Cancer.
Author:	Hazar-Rethinam, Mehlika\|Kleyman, Marianna\|Han, G Celine\|Liu, David\|Ahronian, Leanne G\|Shahzade, Heather A\|Chen, Lifeng\|Parikh, Aparna R\|Allen, Jill N\|Clark, Jeffrey W\|Kwak, Eunice L\|Faris, Jason E\|Murphy, Janet E\|Hong, Theodore S\|Van Seventer, Emily E\|Nad
PMID:	29431697

2603.
Journal:	Cancer Discov. 2018 Apr;8(4):428-443.
Title:	Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAF(V600E)-Mutant Colorectal Cancer.
Author:	Corcoran, Ryan B\|Andre, Thierry\|Atreya, Chloe E\|Schellens, Jan H M\|Yoshino, Takayuki\|Bendell, Johanna C\|Hollebecque, Antoine\|McRee, Autumn J\|Siena, Salvatore\|Middleton, Gary\|Muro, Kei\|Gordon, Michael S\|Tabernero, Josep\|Yaeger, Rona\|O'Dwyer, Peter J\|Humble
PMID:	29431699

2604.
Journal:	J Proteomics. 2018 Apr 15;177:1-10.
Title:	Polyphenol extracts from dried sugarcane inhibit inflammatory mediators in an in vitro colon cancer model.
Author:	Bucio-Noble, Daniel\|Kautto, Liisa\|Krisp, Christoph\|Ball, Malcolm S\|Molloy, Mark P
PMID:	29432917

2605.
Journal:	Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: mcs.a002535.
Title:	Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases.
Author:	Owen, Daniel R\|Wong, Hui-Li\|Bonakdar, Melika\|Jones, Martin\|Hughes, Christopher S\|Morin, Gregg B\|Jones, Steven J M\|Renouf, Daniel J\|Lim, Howard\|Laskin, Janessa\|Marra, Marco\|Yip, Stephen\|Schaeffer, David F
PMID:	29438965

2606.
Journal:	Cell Death Dis. 2018 Feb 15;9(3):271.
Title:	PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d.
Author:	Huang, Lanlan\|Wen, Chuangyu\|Yang, Xiangling\|Lou, Qiong\|Wang, Xiaoyan\|Che, Jia\|Chen, Junxiong\|Yang, Zihuan\|Wu, Xiaojian\|Huang, Meijin\|Lan, Ping\|Wang, Lei\|Iwamoto, Aikichi\|Wang, Jianping\|Liu, Huanliang
PMID:	29449544

2607.
Journal:	Sci Rep. 2018 Feb 19;8(1):3287.
Title:	Common Deregulation of Seven Biological Processes by MicroRNAs in Gastrointestinal Cancers.
Author:	Zhang, Lin\|Zhang, Yuchen\|Wong, Sunny H\|Law, Priscilla T Y\|Zhao, Shan\|Yu, Jun\|Chan, Matthew T V\|Wu, William K K
PMID:	29459716

2608.
Journal:	Clin Drug Investig. 2018 Jun;38(6):553-562.
Title:	First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Author:	Moiseyenko, Vladimir M\|Moiseyenko, Fedor V\|Yanus, Grigoriy A\|Kuligina, Ekatherina Sh\|Sokolenko, Anna P\|Bizin, Ilya V\|Kudriavtsev, Alexey A\|Aleksakhina, Svetlana N\|Volkov, Nikita M\|Chubenko, Vyacheslav A\|Kozyreva, Kseniya S\|Kramchaninov, Mikhail M\|Zhuravle
PMID:	29470838

2609.
Journal:	Cell Biol Toxicol. 2018 Feb 24. pii: 10.1007/s10565-018-9423-3.
Title:	Colorectal cancer spheroid biobanks: multi-level approaches to drug sensitivity studies.
Author:	De Angelis, Maria Laura\|Bruselles, Alessandro\|Francescangeli, Federica\|Pucilli, Flavia\|Vitale, Sara\|Zeuner, Ann\|Tartaglia, Marco\|Baiocchi, Marta
PMID:	29478126

2610.
Journal:	J Enzyme Inhib Med Chem. 2018 Dec;33(1):546-557.
Title:	Anticancer evaluation and molecular modeling of multi-targeted kinase inhibitors based pyrido[2,3-d]pyrimidine scaffold.
Author:	Elzahabi, Heba S A\|Nossier, Eman S\|Khalifa, Nagy M\|Alasfoury, Rania A\|El-Manawaty, May A
PMID:	29482389

2611.
Journal:	Mol Cancer Ther. 2018 Jun;17(6):1280-1290.
Title:	The Unfolded Protein Response: A Novel Therapeutic Target for Poor Prognostic BRAF Mutant Colorectal Cancer.
Author:	Forsythe, Nicholas\|Refaat, Alaa\|Javadi, Arman\|Khawaja, Hajrah\|Weir, Jessica-Anne\|Emam, Heba\|Allen, Wendy L\|Burkamp, Frank\|Popovici, Vlad\|Jithesh, Puthen V\|Isella, Claudio\|Labonte, Melissa J\|Mills, Ian G\|Johnston, Patrick G\|Van Schaeybroeck, Sandra
PMID:	29483217

2612.
Journal:	Gan To Kagaku Ryoho. 2018 Feb;45(2):353-355.
Title:	[A Case of Surgery after Chemotherapy for Cecal Cancer with Onset of the Stenosis of the Colostomy].
Author:	Kono, Teppei\|Yokomizo, Hajime\|Yano, Yuki\|Okayama, Sachiyo\|Satake, Masaya\|Yamada, Yasufumi\|Ida, Arika\|Usui, Takebumi\|Yamaguchi, Kentaro\|Shiozawa, Shunichi\|Yoshimatsu, Kazuhiko\|Shimakawa, Takeshi\|Katsube, Takao\|Kato, Hiroyuki\|Naritaka, Yoshihiko
PMID:	29483445

2613.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Feb 27.
Title:	Clinicopathologic Significance of Intestinal-type Molecules' Expression and Different EGFR Gene Status in Pulmonary Adenocarcinoma.
Author:	Feng, Chang\|Feng, Man\|Gao, Yujun\|Zhao, Xiaogang\|Peng, Chuanliang\|Yang, Xiangshan\|Zhang, Jing
PMID:	29489510

2614.
Journal:	Clin Cancer Res. 2018 Jun 1;24(11):2548-2558.
Title:	Combinations of Bevacizumab and Erlotinib Show Activity in Colorectal Cancer Independent of RAS Status.
Author:	Mesange, Paul\|Bouygues, Anais\|Ferrand, Nathalie\|Sabbah, Michele\|Escargueil, Alexandre E\|Savina, Ariel\|Chibaudel, Benoist\|Tournigand, Christophe\|Andre, Thierry\|de Gramont, Aimery\|Larsen, Annette K
PMID:	29490990

2615.
Journal:	Cancer Sci. 2018 May;109(5):1455-1467.
Title:	Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
Author:	Akao, Yukihiro\|Kumazaki, Minami\|Shinohara, Haruka\|Sugito, Nobuhiko\|Kuranaga, Yuki\|Tsujino, Takuya\|Yoshikawa, Yuki\|Kitade, Yukio
PMID:	29498789

2616.
Journal:	Mol Pharm. 2018 Apr 2;15(4):1432-1444.
Title:	pH-Responsive Nanophotosensitizer for an Enhanced Photodynamic Therapy of Colorectal Cancer Overexpressing EGFR.
Author:	Chu, Wen-Yu\|Tsai, Ming-Hsien\|Peng, Cheng-Liang\|Shih, Ying-Hsia\|Luo, Tsai-Yueh\|Yang, Shu-Jyuan\|Shieh, Ming-Jium
PMID:	29498860

2617.
Journal:	J Exp Clin Cancer Res. 2018 Mar 2;37(1):41.
Title:	Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway.
Author:	Hu, Xiang\|Li, Ya-Qi\|Li, Qing-Guo\|Ma, Yan-Lei\|Peng, Jun-Jie\|Cai, San-Jun
PMID:	29499765

2618.
Journal:	Zhonghua Zhong Liu Za Zhi. 2018 Feb 23;40(2):99-104.
Title:	[Relationships between the enrichment of ETBF, Fn, Hp in intestinal and colorectal cancer].
Author:	Zhang, J\|Lu, X L\|Zhao, G\|Shi, H T\|Geng, Y\|Zhong, W T\|Dong, L
PMID:	29502368

2619.
Journal:	Medicine (Baltimore). 2018 Jan;97(3):e9672.
Title:	Anti epidermal growth factor receptor therapy in small bowel adenocarcinoma: Case report and literature review.
Author:	Falcone, Rosa\|Roberto, Michela\|Filetti, Marco\|Anselmi, Elisabetta\|Marchetti, Paolo
PMID:	29505011

2620.
Journal:	Oncol Rep. 2018 May;39(5):2297-2305.
Title:	Delineating the underlying molecular mechanisms and key genes involved in metastasis of colorectal cancer via bioinformatics analysis.
Author:	Qi, Chao\|Chen, Yuanlei\|Zhou, Yixuan\|Huang, Xucheng\|Li, Guoli\|Zeng, Jin\|Ruan, Zhi\|Xie, Xinyou\|Zhang, Jun
PMID:	29517105

2621.
Journal:	Oncologist. 2018 Aug;23(8):912-918.
Title:	Phase II Study of Preoperative Treatment with External Radiotherapy Plus Panitumumab in Low-Risk, Locally Advanced Rectal Cancer (RaP Study/STAR-03).
Author:	Pinto, Carmine\|Di Bisceglie, Maurizio\|Di Fabio, Francesca\|Bochicchio, Annamaria\|Latiano, Tiziana\|Cordio, Stefano\|Rosati, Gerardo\|Aschele, Carlo\|Marino, Antonella\|Bergamo, Francesca\|Bustreo, Sara\|Frassineti, Luca\|Ciardiello, Fortunato\|Damato, Angela\|Giaqui
PMID:	29523646

2622.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2018 Apr 1;50(4):355-361.
Title:	BRAF and EGFR inhibitors synergize to increase cytotoxic effects and decrease stem cell capacities in BRAF(V600E)-mutant colorectal cancer cells.
Author:	Wu, Zhenhua\|Huang, Mingzhu\|Gong, Yiwei\|Lin, Chen\|Guo, Weijian
PMID:	29534162

2623.
Journal:	Oncotarget. 2018 Jan 31;9(13):11322-11335.
Title:	Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells.
Author:	Hutt, Meike\|Fellermeier-Kopf, Sina\|Seifert, Oliver\|Schmitt, Lisa C\|Pfizenmaier, Klaus\|Kontermann, Roland E
PMID:	29541416

2624.
Journal:	Cell Death Dis. 2018 Apr 1;9(4):417.
Title:	CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7.
Author:	Zeng, Kaixuan\|Chen, Xiaoxiang\|Xu, Mu\|Liu, Xiangxiang\|Hu, Xiuxiu\|Xu, Tao\|Sun, Huiling\|Pan, Yuqin\|He, Bangshun\|Wang, Shukui
PMID:	29549306

2625.
Journal:	Asian Pac J Allergy Immunol. 2018 Mar 12.
Title:	Cutaneous toxicities of epidermal growth factor receptor inhibitors: A prospective study in 60 Asian patients.
Author:	Chularojanamontri, Leena\|Tuchinda, Papapit\|Likitwattananurak, Chayanee\|Pongparit, Kamolwan\|Rujitharanawong, Chuda\|Ithimakin, Suthinee\|Kulthanan, Kanokvalai
PMID:	29549700

2626.
Journal:	Oncotarget. 2018 Jan 13;9(15):12250-12260.
Title:	Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab.
Author:	He, Xuzhi\|Cruz, Jazmina L\|Joseph, Shannon\|Pett, Nicola\|Chew, Hui Yi\|Tuong, Zewen K\|Okano, Satomi\|Kelly, Gabrielle\|Veitch, Margaret\|Simpson, Fiona\|Wells, James W
PMID:	29552307

2627.
Journal:	J BUON. 2018 Jan-Feb;23(1):23-28.
Title:	Prognostic significance of EGFR and COX-2 expression in colorectal cancer and their association. A study in Greek population.
Author:	Mouzakiti, Anna\|Nastos, Constantinos\|Vlachodimitropoulos, Dimitrios\|Gennatas, Constantinos\|Kondi-Pafiti, Agathi\|Voros, Dionisios
PMID:	29552755

2628.
Journal:	Int J Oncol. 2018 Mar 16.
Title:	A novel therapeutic strategy of personalized medicine based on anti-epidermal growth factor receptor monoclonal antibodies in patients with metastatic colorectal cancer.
Author:	Matsuhashi, Nobuhisa\|Takahashi, Takao\|Matsui, Satoshi\|Tanahashi, Toshiyuki\|Imai, Hisashi\|Tanaka, Yoshihiro\|Yamaguchi, Kazuya\|Yoshida, Kazuhiro
PMID:	29568913

2629.
Journal:	Cancer Biol Ther. 2018 Aug 3;19(8):659-663.
Title:	Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?
Author:	Baretti, M\|Personeni, N\|Destro, A\|Santoro, A\|Rimassa, L
PMID:	29580164

2630.
Journal:	Oncotarget. 2018 Feb 16;9(18):14306-14310.
Title:	TP53 mutations and number of alterations correlate with maximum standardized uptake value (SUVmax) determined by positron emission tomography/computed tomography (PET/CT) [(18)F] fluorodeoxyglucose ((18)F-FDG PET).
Author:	Chang, Geraldine H\|Kurzrock, Razelle\|Tran, Lisa\|Schwaederle, Maria\|Hoh, Carl K
PMID:	29581845

2631.
Journal:	Clin Cancer Res. 2018 Aug 1;24(15):3550-3559.
Title:	Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies.
Author:	Toledo, Rodrigo A\|Garralda, Elena\|Mitsi, Maria\|Pons, Tirso\|Monsech, Jorge\|Vega, Estela\|Otero, Alvaro\|Albarran, Maria I\|Banos, Natalia\|Duran, Yolanda\|Bonilla, Victoria\|Sarno, Francesca\|Camacho-Artacho, Marta\|Sanchez-Perez, Tania\|Perea, Sofia\|Alvarez, Rafae
PMID:	29588308

2632.
Journal:	Methods Mol Biol. 2018;1765:281-297.
Title:	Molecular Testing for the Treatment of Advanced Colorectal Cancer: An Overview.
Author:	Lin, Patrick S\|Semrad, Thomas J
PMID:	29589315

2633.
Journal:	Sci Rep. 2018 Mar 28;8(1):5309.
Title:	Metabolomic approach for a rapid identification of natural products with cytotoxic activity against human colorectal cancer cells.
Author:	Graziani, Vittoria\|Scognamiglio, Monica\|Belli, Valentina\|Esposito, Assunta\|D'Abrosca, Brigida\|Chambery, Angela\|Russo, Rosita\|Panella, Marta\|Russo, Aniello\|Ciardiello, Fortunato\|Troiani, Teresa\|Potenza, Nicoletta\|Fiorentino, Antonio
PMID:	29593231

2634.
Journal:	Anticancer Res. 2018 Apr;38(4):2235-2240.
Title:	Racial Disparities in the Molecular Landscape of Cancer.
Author:	Heath, Elisabeth I\|Lynce, Filipa\|Xiu, Joanne\|Ellerbrock, Angela\|Reddy, Sandeep K\|Obeid, Elias\|Liu, Stephen V\|Bollig-Fischer, Aliccia\|Separovic, Duska\|Vanderwalde, Ari
PMID:	29599344

2635.
Journal:	Cancer Discov. 2018 Apr;8(4):389-391.
Title:	Advances on the BRAF Front in Colorectal Cancer.
Author:	Janku, Filip
PMID:	29610287

2636.
Journal:	PLoS One. 2018 Apr 4;13(4):e0193544.
Title:	Prevention of colonic neoplasia with polyethylene glycol: A short term randomized placebo-controlled double-blinded trial.
Author:	Wali, Ramesh K\|Bianchi, Laura\|Kupfer, Sonia\|De La Cruz, Mart\|Jovanovic, Borko\|Weber, Christopher\|Goldberg, Michael J\|Rodriguez, L M\|Bergan, Raymond\|Rubin, David\|Tull, Mary Beth\|Richmond, Ellen\|Parker, Beth\|Khan, Seema\|Roy, Hemant K
PMID:	29617381

2637.
Journal:	Cell Physiol Biochem. 2018;46(2):829-846.
Title:	Gambogic Acid Efficiently Kills Stem-Like Colorectal Cancer Cells by Upregulating ZFP36 Expression.
Author:	Wei, Fang\|Zhang, Tong\|Yang, Zhi\|Wei, Jian-Chang\|Shen, Hong-Fen\|Xiao, Dong\|Wang, Qiang\|Yang, Ping\|Chen, Hua-Cui\|Hu, He\|Chen, Zhuan-Peng\|Huang, Qing\|Li, Wang-Lin\|Cao, Jie
PMID:	29627822

2638.
Journal:	Gastrointest Cancer. 2018;8:13-23.
Title:	Emerging treatment options for BRAF-mutant colorectal cancer.
Author:	Ursem, Carling\|Atreya, Chloe E\|Van Loon, Katherine
PMID:	29628780

2639.
Journal:	Cesk Patol. 2018 Spring;54(1):17-21.
Title:	[Prediction of EGFR blockade responses in metastatic colorectal carcinoma].
Author:	Fabian, Pavel\|Nemecek, Radim
PMID:	29631407

2640.
Journal:	Cancer Biother Radiopharm. 2018 Mar;33(2):60-64.
Title:	PTPN12 Affects Nasopharyngeal Carcinoma Cell Proliferation and Migration Through Regulating EGFR.
Author:	Lin, Qinghai\|Wang, Huige\|Lin, Xinqiang\|Zhang, Wenrui\|Huang, Shuhua\|Zheng, Yandan
PMID:	29634414

2641.
Journal:	Oncotarget. 2018 Mar 23;9(22):15968-15983.
Title:	Promotion of malignant phenotype after disruption of the three-dimensional structure of cultured spheroids from colorectal cancer.
Author:	Piulats, Jose M\|Kondo, Jumpei\|Endo, Hiroko\|Ono, Hiromasa\|Hagihara, Takeshi\|Okuyama, Hiroaki\|Nishizawa, Yasuko\|Tomita, Yasuhiko\|Ohue, Masayuki\|Okita, Kouki\|Oyama, Hidejiro\|Bono, Hidemasa\|Masuko, Takashi\|Inoue, Masahiro
PMID:	29662620

2642.
Journal:	J Exp Clin Cancer Res. 2018 Apr 17;37(1):84.
Title:	Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.
Author:	Mendes Oliveira, Duarte\|Grillone, Katia\|Mignogna, Chiara\|De Falco, Valentina\|Laudanna, Carmelo\|Biamonte, Flavia\|Locane, Rosa\|Corcione, Francesco\|Fabozzi, Massimiliano\|Sacco, Rosario\|Viglietto, Giuseppe\|Malanga, Donatella\|Rizzuto, Antonia
PMID:	29665843

2643.
Journal:	Oncotarget. 2018 Mar 30;9(24):17066-17077.
Title:	Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells.
Author:	Scheers, Nathalie M\|Pereira, Dora I A\|Faria, Nuno\|Powell, Jonathan J
PMID:	29682205

2644.
Journal:	Mol Pharm. 2018 Jun 4;15(6):2316-2326.
Title:	Nanoencapsulation of Novel Inhibitors of PNKP for Selective Sensitization to Ionizing Radiation and Irinotecan and Induction of Synthetic Lethality.
Author:	Shire, Zahra\|Vakili, Mohammad Reza\|Morgan, Timothy D R\|Hall, Dennis G\|Lavasanifar, Afsaneh\|Weinfeld, Michael
PMID:	29688721

2645.
Journal:	Eur J Cancer Prev. 2018 Apr 23.
Title:	Selected proliferation markers correlated with dynamics of growth in colorectal cancer.
Author:	Luo, Wu-Xia\|Chen, Ye\|Li, Yun-Tao\|Tang, Jie\|Ding, Jing\|Du, Yang\|Wu, Qiang\|Liu, Ji-Yan
PMID:	29688906

2646.
Journal:	BMC Med Genomics. 2018 Apr 20;11(Suppl 2):29.
Title:	Population-based statistical inference for temporal sequence of somatic mutations in cancer genomes.
Author:	Rhee, Je-Keun\|Kim, Tae-Min
PMID:	29697365

2647.
Journal:	Oncotarget. 2018 Apr 6;9(26):18510-18517.
Title:	Histogram analysis of ADC in rectal cancer: associations with different histopathological findings including expression of EGFR, Hif1-alpha, VEGF, p53, PD1, and KI 67. A preliminary study.
Author:	Meyer, Hans Jonas\|Hohn, Annekathrin\|Surov, Alexey
PMID:	29719621

2648.
Journal:	Clin Colon Rectal Surg. 2018 May;31(3):147-152.
Title:	Update on Sporadic Colorectal Cancer Genetics.
Author:	Hardiman, Karin M
PMID:	29720900

2649.
Journal:	Oncotarget. 2018 Apr 10;9(27):18698-18711.
Title:	Consensus molecular subtypes classification of colorectal cancer as a predictive factor for chemotherapeutic efficacy against metastatic colorectal cancer.
Author:	Okita, Akira\|Takahashi, Shin\|Ouchi, Kota\|Inoue, Masahiro\|Watanabe, Mika\|Endo, Mareyuki\|Honda, Hiroshi\|Yamada, Yasuhide\|Ishioka, Chikashi
PMID:	29721154

2650.
Journal:	Future Oncol. 2018 May 4.
Title:	Management and grading of EGFR inhibitor-induced cutaneous toxicity.
Author:	Beech, Janette\|Germetaki, Theodora\|Judge, Mary\|Paton, Nina\|Collins, Joanne\|Garbutt, Abigail\|Braun, Michael\|Fenwick, Jill\|Saunders, Mark P
PMID:	29727211

2651.
Journal:	Thorac Cancer. 2018 Jul;9(7):885-891.
Title:	EGFR exon 20 insertion mutation in advanced thymic squamous cell carcinoma: Response to apatinib and clinical outcomes.
Author:	Yudong, Su\|Zhaoting, Meng\|Xinyue, Wang\|Li, Lin\|Xiaoyan, Xu\|Ran, Zuo\|Jinliang, Chen\|Peng, Chen
PMID:	29740957

2652.
Journal:	Expert Opin Drug Saf. 2018 Jun;17(6):643-650.
Title:	The safety of trifluridine and tipiracil for the treatment of metastatic colorectal cancer.
Author:	Martinez-Perez, Julia\|Riesco-Martinez, M Carmen\|Garcia-Carbonero, Rocio
PMID:	29745737

2653.
Journal:	Pathology. 2018 Jun;50(4):389-401.
Title:	Implementation of next generation sequencing technology for somatic mutation detection in routine laboratory practice.
Author:	Giardina, Tindaro\|Robinson, Cleo\|Grieu-Iacopetta, Fabienne\|Millward, Michael\|Iacopetta, Barry\|Spagnolo, Dominic\|Amanuel, Benhur
PMID:	29752127

2654.
Journal:	Curr Treat Options Oncol. 2018 May 11;19(6):29.
Title:	Promising New Agents for Colorectal Cancer.
Author:	Das, Satya\|Ciombor, Kristen K\|Haraldsdottir, Sigurdis\|Goldberg, Richard M
PMID:	29752549

2655.
Journal:	Br J Cancer. 2018 May 14. pii: 10.1038/s41416-018-0086-x.
Title:	AZ304, a novel dual BRAF inhibitor, exerts anti-tumour effects in colorectal cancer independently of BRAF genetic status.
Author:	Ma, Rui\|Xu, Ling\|Qu, Xiujuan\|Che, Xiaofang\|Zhang, Ye\|Fan, Yibo\|Li, Ce\|Guo, Tianshu\|Hou, Kezuo\|Hu, Xuejun\|Drew, Lisa\|Shen, Minhui\|Cheung, Tony\|Liu, Yunpeng
PMID:	29755114

2656.
Journal:	Oncogene. 2018 May 14. pii: 10.1038/s41388-018-0289-x.
Title:	Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer.
Author:	Knickelbein, Kyle\|Tong, Jingshan\|Chen, Dongshi\|Wang, Yi-Jun\|Misale, Sandra\|Bardelli, Alberto\|Yu, Jian\|Zhang, Lin
PMID:	29755130

2657.
Journal:	Oncotarget. 2018 Apr 17;9(29):20761-20768.
Title:	Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience.
Author:	D'Haene, Nicky\|Fontanges, Quitterie\|De Neve, Nancy\|Blanchard, Oriane\|Melendez, Barbara\|Delos, Monique\|Dehou, Marie-Francoise\|Maris, Calliope\|Nagy, Nathalie\|Rousseau, Emmanuel\|Vandenhove, Josse\|Gilles, Andre\|De Prez, Carine\|Verset, Laurine\|Van Craynest, Ma
PMID:	29755687

2658.
Journal:	Chin Clin Oncol. 2018 Apr;7(2):17.
Title:	The evolving role of immune oncology in colorectal cancer.
Author:	Dawood, Shaheenah
PMID:	29764162

2659.
Journal:	Oncologist. 2018 Sep;23(9):1004-e102.
Title:	Phase II Study of Irinotecan Plus Panitumumab as Second-Line Therapy for Patients with Advanced Esophageal Adenocarcinoma.
Author:	Yoon, Harry\|Karapetyan, Lilit\|Choudhary, Anita\|Kosozi, Ramla\|Bali, Gurvinder Singh\|Zaidi, Ali H\|Atasoy, Ajlan\|Forastiere, Arlene A\|Gibson, Michael K
PMID:	29769385

2660.
Journal:	Front Pharmacol. 2018 May 3;9:441.
Title:	First Biologic Drug in the Treatment of RAS Wild-Type Metastatic Colorectal Cancer: Anti-EGFR or Bevacizumab? Results From a Meta-Analysis.
Author:	Ottaiano, Alessandro\|De Stefano, Alfonso\|Capozzi, Monica\|Nappi, Anna\|De Divitiis, Chiara\|Romano, Carmela\|Silvestro, Lucrezia\|Cassata, Antonino\|Casaretti, Rossana\|Tafuto, Salvatore\|Caraglia, Michele\|Berretta, Massimiliano\|Nasti, Guglielmo\|Avallone, Antonio
PMID:	29773991

2661.
Journal:	Clin Cancer Res. 2018 Aug 1;24(15):3528-3538.
Title:	The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 21,807 Advanced Cancer Patients.
Author:	Zill, Oliver A\|Banks, Kimberly C\|Fairclough, Stephen R\|Mortimer, Stefanie A\|Vowles, James V\|Mokhtari, Reza\|Gandara, David R\|Mack, Philip C\|Odegaard, Justin I\|Nagy, Rebecca J\|Baca, Arthur M\|Eltoukhy, Helmy\|Chudova, Darya I\|Lanman, Richard B\|Talasaz, AmirAl
PMID:	29776953

2662.
Journal:	Neoplasma. 2018 Mar 14;65(3):415-424.
Title:	Novel insights into transcriptional dysregulation in colorectal cancer.
Author:	Feodorova, Y\|Tashkova, D\|Koev, I\|Todorov, A\|Kostov, G\|Simitchiev, K\|Belovejdov, V\|Dimov, R\|Sarafian, V
PMID:	29788743

2663.
Journal:	Drugs. 2018 Jun;78(8):789-798.
Title:	Colorectal Cancer: Why Does Side Matter?
Author:	Gallois, Claire\|Pernot, Simon\|Zaanan, Aziz\|Taieb, Julien
PMID:	29790124

2664.
Journal:	Curr Treat Options Oncol. 2018 May 23;19(6):31.
Title:	Right Versus Left Colon Cancer: Resectable and Metastatic Disease.
Author:	Ghidini, Michele\|Petrelli, Fausto\|Tomasello, Gianluca
PMID:	29796712

2665.
Journal:	Neoplasia. 2018 Jul;20(7):668-677.
Title:	Biologic Response of Colorectal Cancer Xenograft Tumors to Sequential Treatment with Panitumumab and Bevacizumab.
Author:	Taniguchi, Hiroya\|Baba, Yuji\|Sagiya, Yoji\|Gotou, Masamitsu\|Nakamura, Kazuhide\|Sawada, Hiroshi\|Yamanaka, Kazunori\|Sakakibara, Yukiko\|Mori, Ikuo\|Hikichi, Yukiko\|Soeda, Junpei\|Baba, Hideo
PMID:	29802988

2666.
Journal:	Future Oncol. 2018 Jun;14(14):1339-1346.
Title:	Phase III study with FOLFIRI + cetuximab versus FOLFIRI + cetuximab followed by cetuximab alone in RAS and BRAF WT mCRC.
Author:	Pinto, Carmine\|Normanno, Nicola\|Orlandi, Armando\|Fenizia, Francesca\|Damato, Angela\|Maiello, Evaristo\|Tamburini, Emiliano\|Di Costanzo, Francesco\|Tonini, Giuseppe\|Bilancia, Domenico\|Corsi, Domenico\|Pisconti, Salvatore\|Ferrau, Francesco\|Gori, Stefania\|Daniel
PMID:	29846100

2667.
Journal:	Anal Cell Pathol (Amst). 2018 Apr 16;2018:1616973.
Title:	Angiodrastic Chemokines in Colorectal Cancer: Clinicopathological Correlations.
Author:	Emmanouil, George\|Ayiomamitis, George\|Zizi-Sermpetzoglou, Adamantia\|Tzardi, Maria\|Moursellas, Andrew\|Voumvouraki, Argyro\|Kouroumalis, Elias
PMID:	29850390

2668.
Journal:	Oncotarget. 2018 Apr 27;9(32):22749-22768.
Title:	Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.
Author:	Oliveira, Duarte Mendes\|Mirante, Teresa\|Mignogna, Chiara\|Scrima, Marianna\|Migliozzi, Simona\|Rocco, Gaetano\|Franco, Renato\|Corcione, Francesco\|Viglietto, Giuseppe\|Malanga, Donatella\|Rizzuto, Antonia
PMID:	29854313

2669.
Journal:	Med Oncol. 2018 May 31;35(7):101.
Title:	Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping.
Author:	Papaxoinis, George\|Kotoula, Vassiliki\|Giannoulatou, Eleni\|Koliou, Georgia-Angeliki\|Karavasilis, Vasilios\|Lakis, Sotirios\|Koureas, Andreas\|Bobos, Mattheos\|Chalaralambous, Elpida\|Daskalaki, Emily\|Chatzopoulos, Kyriakos\|Tsironis, George\|Pazarli, Elisavet\|Chr
PMID:	29855806

2670.
Journal:	Ann Gastroenterol Surg. 2018 Apr 17;2(3):167-175.
Title:	Recent advances in treatment for colorectal liver metastasis.
Author:	Oki, Eiji\|Ando, Koji\|Nakanishi, Ryota\|Sugiyama, Masahiko\|Nakashima, Yuichiro\|Kubo, Nobuhide\|Kudou, Kensuke\|Saeki, Hiroshi\|Nozoe, Tadahiro\|Emi, Yasunori\|Maehara, Yoshihiko
PMID:	29863162

2671.
Journal:	Pathol Oncol Res. 2018 Jun 7. pii: 10.1007/s12253-018-0434-4.
Title:	The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells.
Author:	Sticz, Tamas\|Molnar, Anna\|Danko, Titanilla\|Hujber, Zoltan\|Petovari, Gabor\|Nagy, Noemi\|Vegso, Gyula\|Kopper, Laszlo\|Sebestyen, Anna
PMID:	29882195

2672.
Journal:	Exp Mol Med. 2018 Jun 6;50(6):71.
Title:	Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of beta-catenin signaling.
Author:	Shin, Wookjin\|Lee, Sang-Kyu\|Hwang, Jeong-Ha\|Park, Jong-Chan\|Cho, Yong-Hee\|Ro, Eun Ji\|Song, Yeonhwa\|Seo, Haeng Ran\|Choi, Kang-Yell
PMID:	29884842

2673.
Journal:	Cell Cycle. 2018;17(10):1212-1219.
Title:	IGF1/IGF1R and microRNA let-7e down-regulate each other and modulate proliferation and migration of colorectal cancer cells.
Author:	Li, Zhenjun\|Pan, Weihuo\|Shen, Yi\|Chen, Zhiliang\|Zhang, Lihua\|Zhang, Yuping\|Luo, Quan\|Ying, Xiaojiang
PMID:	29886785

2674.
Journal:	Jpn J Clin Oncol. 2018 Aug 1;48(8):718-727.
Title:	Mucositis with anti-EGFR monoclonal antibody in cancer patients: a meta-analysis of randomized controlled trials.
Author:	Li, Jing\|Xie, Jing
PMID:	29893861

2675.
Journal:	Br J Cancer. 2018 Jun 14. pii: 10.1038/s41416-018-0130-x.
Title:	Correction: Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.
Author:	Lievre, Astrid\|Ouine, Berengere\|Canet, Jim\|Cartier, Aurelie\|Amar, Yael\|Cacheux, Wulfran\|Mariani, Odette\|Guimbaud, Rosine\|Selves, Janick\|Lecomte, Thierry\|Guyetant, Serge\|Bieche, Ivan\|Berger, Frederique\|de Koning, Leanne
PMID:	29899390

2676.
Journal:	Biosci Rep. 2018 Jul 31;38(4). pii: BSR20180322.
Title:	Circulating tumor DNA detectable in early- and late-stage colorectal cancer patients.
Author:	Yang, Ying-Chi\|Wang, Dong\|Jin, Lan\|Yao, Hong-Wei\|Zhang, Jing-Hui\|Wang, Jin\|Zhao, Xiao-Mu\|Shen, Chun-Ying\|Chen, Wei\|Wang, Xue-Liang\|Shi, Rong\|Chen, Si-Yi\|Zhang, Zhong-Tao
PMID:	29914973

2677.
Journal:	Cancer Chemother Pharmacol. 2018 Sep;82(3):407-418.
Title:	A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer.
Author:	Patnaik, Amita\|Gordon, Michael\|Tsai, Frank\|Papadopoulous, Kyri\|Rasco, Drew\|Beeram, S Muralidhar\|Fu, Siqing\|Janku, Filip\|Hynes, Scott M\|Gundala, Sushma R\|Willard, Melinda D\|Zhang, Wei\|Lin, Aimee Bence\|Hong, David
PMID:	29926131

2678.
Journal:	Per Med. 2018 Jul 1;15(4):319-327.
Title:	The interference between oxaliplatin & anti-EGFR therapies: a different hypothesis to explain the 'unexplainable'.
Author:	Basso, Michele\|Dadduzio, Vincenzo\|Rossi, Sabrina\|D'Argento, Ettore\|Strippoli, Antonia\|Di Salvatore, Mariantonietta\|Orlandi, Armando\|Zurlo, Valeria\|Di Noia, Vincenzo\|Barone, Carlo
PMID:	29927360

2679.
Journal:	Oncol Lett. 2018 Jul;16(1):27-33.
Title:	Research progress on common adverse events caused by targeted therapy for colorectal cancer.
Author:	Zhang, Bo\|Fang, Chenyan\|Deng, Dehou\|Xia, Liang
PMID:	29928383

2680.
Journal:	Oncol Lett. 2018 Jul;16(1):326-334.
Title:	Cetuximab improves AZD6244 antitumor activity in colorectal cancer HT29 cells in vitro and in nude mice by attenuating HER3/Akt pathway activation.
Author:	Zhang, Qin\|Xiao, He\|Jin, Feng\|Li, Mengxia\|Luo, Jia\|Wang, Ge
PMID:	29928418

2681.
Journal:	Surg Oncol. 2018 Jun;27(2):280-288.
Title:	Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence.
Author:	Tsilimigras, Diamantis I\|Ntanasis-Stathopoulos, Ioannis\|Bagante, Fabio\|Moris, Demetrios\|Cloyd, Jordan\|Spartalis, Eleftherios\|Pawlik, Timothy M
PMID:	29937183

2682.
Journal:	Rom J Morphol Embryol. 2018;59(1):121-129.
Title:	Mutational status of KRAS and MMR genes in a series of colorectal carcinoma cases.
Author:	Cionca, Florina Lucia\|Dobre, Maria\|Dobrea, Camelia Marioara\|Iosif, Cristina Ileana\|Comanescu, Maria Victoria\|Ardeleanu, Carmen Maria
PMID:	29940619

2683.
Journal:	Drugs. 2018 Jul;78(11):1133-1144.
Title:	Regorafenib: A Review in Metastatic Colorectal Cancer.
Author:	Dhillon, Sohita
PMID:	29943375

2684.
Journal:	BMC Cancer. 2018 Jun 27;18(1):695.
Title:	Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author:	Molnar, Bela\|Galamb, Orsolya\|Peterfia, Balint\|Wichmann, Barnabas\|Csabai, Istvan\|Bodor, Andras\|Kalmar, Alexandra\|Szigeti, Krisztina Andrea\|Bartak, Barbara Kinga\|Nagy, Zsofia Brigitta\|Valcz, Gabor\|Patai, Arpad V\|Igaz, Peter\|Tulassay, Zsolt
PMID:	29945573

2685.
Journal:	J Coll Physicians Surg Pak. 2018 Jul;28(7):527-531.
Title:	Expression of Epidermal Growth Factor Receptor in Colorectal Adenocarcinoma and its Correlation with Clinicopathological Factors.
Author:	Nemanqani, Dalal M\|Aftab, Kanwal\|Al-Malki, Samia H\|Al-Sufyani, Walaa M
PMID:	29950257

2686.
Journal:	Biochem Biophys Res Commun. 2018 Sep 18;503(4):2333-2339.
Title:	Knockdown of ADAM17 inhibits cell proliferation and increases oxaliplatin sensitivity in HCT-8 colorectal cancer through EGFR-PI3K-AKT activation.
Author:	Zhang, Qi\|Wang, Changyou\|Han, Xuechao\|Yang, Guanghua\|Ge, Zhipeng\|Zhang, Guozhi
PMID:	29964008

2687.
Journal:	Mol Cell Proteomics. 2018 Oct;17(10):1892-1908.
Title:	A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.
Author:	Ressa, Anna\|Bosdriesz, Evert\|de Ligt, Joep\|Mainardi, Sara\|Maddalo, Gianluca\|Prahallad, Anirudh\|Jager, Myrthe\|de la Fonteijne, Lisanne\|Fitzpatrick, Martin\|Groten, Stijn\|Altelaar, A F Maarten\|Bernards, Rene\|Cuppen, Edwin\|Wessels, Lodewyk\|Heck, Albert J R
PMID:	29970458

2688.
Journal:	J Cancer Res Ther. 2018 Jun;14(Supplement):S388-S393.
Title:	Longan flower proanthocyanidins induce apoptosis in HT-29 colorectal carcinoma spheroids.
Author:	Chung, Yuan-Chiang\|Chiang, Hua-Che\|Chang, Hsiang\|Lin, Chih-Cheng\|Lo, Li-Tsai\|Wang, Ai-Yih\|Chou, Kuo-Feng\|Hsu, Chih-Ping
PMID:	29970694

2689.
Journal:	Cancer Lett. 2018 Oct 1;433:165-175.
Title:	Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells.
Author:	Liang, Kang-Hao\|Tso, Hsien-Cheng\|Hung, Shao-Hsi\|Kuan, I-I\|Lai, Jun-Kai\|Ke, Feng-Yi\|Chuang, Yi-Ting\|Liu, I-Ju\|Wang, Yi-Ping\|Chen, Ruey-Hwa\|Wu, Han-Chung
PMID:	29981429

2690.
Journal:	Carcinogenesis. 2018 Jul 3;39(7):911-920.
Title:	Nitric oxide-donating aspirin (NO-Aspirin) suppresses lung tumorigenesis in vitro and in vivo and these effects are associated with modulation of the EGFR signaling pathway.
Author:	Song, Jung Min\|Upadhyaya, Pramod\|Kassie, Fekadu
PMID:	29982425

2691.
Journal:	World J Surg Oncol. 2018 Jul 12;16(1):138.
Title:	Are ADC values of readout-segmented echo-planar diffusion-weighted imaging (RESOLVE) correlated with pathological prognostic factors in rectal adenocarcinoma?
Author:	Tang, Cui\|Lin, Mou-Bin\|Xu, Jin-Lei\|Zhang, Lan-Hua\|Zuo, Xiao-Ming\|Zhang, Zhong-Shuai\|Liu, Meng-Xiao\|Xu, Jin-Ming
PMID:	30001205

2692.
Journal:	PLoS One. 2018 Jul 12;13(7):e0200163.
Title:	Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth.
Author:	Baumer, Nicole\|Rehkamper, Jan\|Appel, Neele\|Terheyden, Lisa\|Hartmann, Wolfgang\|Wardelmann, Eva\|Buchholz, Frank\|Muller-Tidow, Carsten\|Berdel, Wolfgang E\|Baumer, Sebastian
PMID:	30001368

2693.
Journal:	Oncol Lett. 2018 Aug;16(2):1809-1814.
Title:	Overexpression of the long noncoding RNA CCAT1 promotes metastasis via epithelial-to-mesenchymal transition in lung adenocarcinoma.
Author:	Lin, Heping\|Cheng, Wei\|Yan, Hanhan\|Zhang, Xiaodiao
PMID:	30008869

2694.
Journal:	Expert Rev Anticancer Ther. 2018 Oct;18(10):991-1006.
Title:	Targeted therapy for metastatic colorectal cancer.
Author:	Price, Timothy J\|Tang, Monica\|Gibbs, Peter\|Haller, Daniel G\|Peeters, Marc\|Arnold, Dirk\|Segelov, Eva\|Roy, Amitesh\|Tebbutt, Niall\|Pavlakis, Nick\|Karapetis, Chris\|Burge, Matthew\|Shapiro, Jeremy
PMID:	30019590

2695.
Journal:	Free Radic Biol Med. 2018 Oct;126:41-54.
Title:	Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability.
Author:	Afrin, Sadia\|Giampieri, Francesca\|Forbes-Hernandez, Tamara Y\|Gasparrini, Massimiliano\|Amici, Adolfo\|Cianciosi, Danila\|Quiles, Jose L\|Battino, Maurizio
PMID:	30056083

2696.
Journal:	J Biomed Sci. 2018 Aug 2;25(1):60.
Title:	STAT3 exacerbates survival of cancer stem-like tumorspheres in EGFR-positive colorectal cancers: RNAseq analysis and therapeutic screening.
Author:	Cheng, Chun-Chia\|Liao, Po-Nien\|Ho, Ai-Sheng\|Lim, Ken-Hong\|Chang, Jungshan\|Su, Ying-Wen\|Chen, Caleb Gon-Shen\|Chiang, Ya-Wen\|Yang, Bi-Ling\|Lin, Huan-Chau\|Chang, Yu-Cheng\|Chang, Chun-Chao\|Chang, Yi-Fang
PMID:	30068339

2697.
Journal:	Microrna. 2018 Aug 2. pii: MIRNA-EPUB-92141.
Title:	Computational Analysis of miRNA and their Gene Targets Significantly Involved in Colorectal Cancer Progression.
Author:	Kandhavelu, Jeyalakshmi\|Subramanian, Kumar\|Khan, Amber\|Omar, Aadilah\|Ruff, Paul\|Penny, Clement
PMID:	30073936

2698.
Journal:	Drug Resist Updat. 2018 Jul;39:18-40.
Title:	Host genetic profiling to increase drug safety in colorectal cancer from discovery to implementation.
Author:	Cecchin, Erika\|De Mattia, Elena\|Ecca, Fabrizio\|Toffoli, Giuseppe
PMID:	30075835

2699.
Journal:	Ann Saudi Med. 2018 Jul-Aug;38(4):251-259.
Title:	Molecular characteristics of colorectal cancer in a Middle Eastern population in a single institution.
Author:	Ibrahim, Tony\|Saer-Ghorra, Claude\|Trak-Smayra, Vivane\|Nadiri, Samah\|Yazbeck, Charbel\|Baz, Maria\|Kattan, Joseph G
PMID:	30078023

2700.
Journal:	Adv Clin Exp Med. 2018 Aug 7.
Title:	Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study.
Author:	Wojas-Krawczyk, Kamila\|Kalinka-Warzocha, Ewa\|Reszka, Katarzyna\|Nicos, Marcin\|Szumilo, Justyna\|Mandziuk, Slawomir\|Szczepaniak, Katarzyna\|Kupnicka, Dorota\|Lewandowski, Remigiusz\|Milanowski, Janusz\|Krawczyk, Pawel
PMID:	30085422

2701.
Journal:	Target Oncol. 2018 Aug 9. pii: 10.1007/s11523-018-0586-x.
Title:	Vitamin D Deficiency has a Negative Impact on Cetuximab-Mediated Cellular Cytotoxicity against Human Colon Carcinoma Cells.
Author:	Mortara, Lorenzo\|Gariboldi, Marzia B\|Bosi, Annalisa\|Bregni, Marco\|Pinotti, Graziella\|Guasti, Luigina\|Squizzato, Alessandro\|Noonan, Douglas M\|Monti, Elena\|Campiotti, Leonardo
PMID:	30090970

2702.
Journal:	Expert Rev Anticancer Ther. 2018 Aug 21:1-8.
Title:	Current and future therapies for targeting HER2 mutations in gastrointestinal cancer.
Author:	El Dika, Imane\|Ilson, David H
PMID:	30092682

2703.
Journal:	Hum Pathol. 2018 Aug 7. pii: S0046-8177(18)30296-X.
Title:	EGFR gene copy number decreases during anti-EGFR antibody therapy in colorectal cancer.
Author:	Birkman, Eva-Maria\|Avoranta, Tuulia\|Algars, Annika\|Korkeila, Eija\|Lintunen, Minnamaija\|Lahtinen, Laura\|Kuopio, Teijo\|Ristamaki, Raija\|Carpen, Olli\|Sundstrom, Jari
PMID:	30096327

2704.
Journal:	Ann Transl Med. 2018 Jul;6(14):285.
Title:	Precision oncology in liver cancer.
Author:	Sullivan, Kevin M\|Kenerson, Heidi L\|Pillarisetty, Venu G\|Riehle, Kimberly J\|Yeung, Raymond S
PMID:	30105235

2705.
Journal:	Oncol Rep. 2018 Oct;40(4):2171-2182.
Title:	Inhibition of YAP reverses primary resistance to EGFR inhibitors in colorectal cancer cells.
Author:	Liu, Bi-Sheng\|Xia, Hong-Wei\|Zhou, Sheng\|Liu, Qing\|Tang, Qiu-Lin\|Bi, Na-Xi\|Zhou, Ji-Tao\|Gong, Qi-Yong\|Nie, Yong-Zhan\|Bi, Feng
PMID:	30106444

2706.
Journal:	Bladder Cancer. 2018 Jul 30;4(3):269-282.
Title:	A Gene Expression Signature Predicts Bladder Cancer Cell Line Sensitivity to EGFR Inhibition.
Author:	Goodspeed, Andrew\|Jean, Annie\|Theodorescu, Dan\|Costello, James C
PMID:	30112438

2707.
Journal:	Gastroenterology Res. 2018 Aug;11(4):264-273.
Title:	Difference Between Left-Sided and Right-Sided Colorectal Cancer: A Focused Review of Literature.
Author:	Baran, Burcin\|Mert Ozupek, Nazli\|Yerli Tetik, Nihal\|Acar, Emine\|Bekcioglu, Omer\|Baskin, Yasemin
PMID:	30116425

2708.
Journal:	PLoS One. 2018 Aug 17;13(8):e0200836.
Title:	Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations.
Author:	Pal, Rekha\|Wei, Ning\|Song, Nan\|Wu, Shaoyu\|Kim, Rim S\|Wang, Ying\|Gavin, Patrick G\|Lucas, Peter C\|Srinivasan, Ashok\|Allegra, Carmen J\|Jacobs, Samuel A\|Paik, Soonmyung\|Schmitz, John C\|Pogue-Geile, Katherine L
PMID:	30118499

2709.
Journal:	Cancer Manag Res. 2018 Aug 1;10:2289-2301.
Title:	Development of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer.
Author:	Pan, Jing-Hua\|Zhou, Hong\|Zhu, Sheng-Bin\|Huang, Jin-Lian\|Zhao, Xiao-Xu\|Ding, Hui\|Pan, Yun-Long
PMID:	30122982

2710.
Journal:	Sci Rep. 2018 Aug 20;8(1):12424.
Title:	The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway.
Author:	Ta, Ngoc Ly\|Chakrabandhu, Krittalak\|Huault, Sebastien\|Hueber, Anne-Odile
PMID:	30127519

2711.
Journal:	Digestion. 2018 Aug 21;98(4):263-269.
Title:	Anti-EGF Receptor-Based Conversion Chemotherapy in RAS Wild-Type Colorectal Cancer Patients: Impact on Survival and Resection Rates.
Author:	Koch, Christine\|Schmidt, Niklas\|Winkelmann, Ria\|Eichler, Katrin\|Pession, Ursula\|Bechstein, Wolf Otto\|Zeuzem, Stefan\|Waidmann, Oliver\|Trojan, Jorg
PMID:	30130797

2712.
Journal:	Int J Oncol. 2018 Nov;53(5):1869-1880.
Title:	COL1A1: A potential therapeutic target for colorectal cancer expressing wild-type or mutant KRAS.
Author:	Zhang, Zheying\|Fang, Cheng\|Wang, Yongxia\|Zhang, Jinghang\|Yu, Jian\|Zhang, Yongxi\|Wang, Xianwei\|Zhong, Jiateng
PMID:	30132520

2713.
Journal:	Contemp Oncol (Pozn). 2018;22(2):75-85.
Title:	Quality and practical aspects of pathological and molecular diagnostics in metastatic colorectal cancer (mCRC).
Author:	Tysarowski, Andrzej\|Nasierowska-Guttmejer, Anna
PMID:	30150883

2714.
Journal:	Nanoscale. 2018 Sep 13;10(35):16738-16749.
Title:	EGFR-targeted liposomal nanohybrid cerasomes: theranostic function and immune checkpoint inhibition in a mouse model of colorectal cancer.
Author:	Li, Yuan\|Du, Yang\|Liang, Xiaolong\|Sun, Ting\|Xue, Huadan\|Tian, Jie\|Jin, Zhengyu
PMID:	30156250

2715.
Journal:	Cell Death Dis. 2018 Aug 29;9(9):877.
Title:	Novel beta-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer.
Author:	Kim, Su Jin\|Noh, Tae Hwan\|Son, Sujin\|Kim, Do Hyun\|Kim, Wooseong\|Lee, Yunna\|Choo, Jieun\|Heo, Gwangbeom\|Kim, Min Jae\|Chung, Hae Young\|Jung, Yunjin\|Jung, Jee Hyung\|Moon, Hyung Ryong\|Im, Eunok
PMID:	30158525

2716.
Journal:	Cancer Discov. 2018 Aug 30. pii: 2159-8290.CD-17-0891.
Title:	Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial.
Author:	Khan, Khurum H\|Cunningham, David\|Werner, Benjamin\|Vlachogiannis, Georgios\|Spiteri, Inmaculada\|Heide, Timon\|Mateos, Javier Fernandez\|Vatsiou, Alexandra\|Lampis, Andrea\|Darvish Damavandi, Mahnaz\|Lote, Hazel\|Huntingford, Ian S\|Hedayat, Somaieh\|Chau, Ian\|Tunar
PMID:	30166348

2717.
Journal:	J Cancer Res Clin Oncol. 2018 Aug 31. pii: 10.1007/s00432-018-2742-1.
Title:	The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing.
Author:	Zou, Shuang-Mei\|Li, Wei-Hua\|Wang, Wen-Miao\|Li, Wen-Bin\|Shi, Su-Sheng\|Ying, Jian-Ming\|Lyu, Ning
PMID:	30171333

2718.
Journal:	Surg Endosc. 2018 Aug 31. pii: 10.1007/s00464-018-6411-x.
Title:	Colonic stent-induced mechanical compression may suppress cancer cell proliferation in malignant large bowel obstruction.
Author:	Matsuda, Akihisa\|Miyashita, Masao\|Matsumoto, Satoshi\|Sakurazawa, Nobuyuki\|Kawano, Youichi\|Yamahatsu, Kazuya\|Sekiguchi, Kumiko\|Yamada, Marina\|Hatori, Tsutomu\|Yoshida, Hiroshi
PMID:	30171397

2719.
Journal:	Biomed Res Int. 2018 Aug 13;2018:3724393.
Title:	Histogram Analysis of Perfusion Parameters from Dynamic Contrast-Enhanced MR Imaging with Tumor Characteristics and Therapeutic Response in Locally Advanced Rectal Cancer.
Author:	Yeo, Dong Myung\|Oh, Soon Nam\|Choi, Moon Hyung\|Lee, Sung Hak\|Lee, Myung Ah\|Jung, Seung Eun
PMID:	30186857

2720.
Journal:	Horm Cancer. 2018 Sep 5. pii: 10.1007/s12672-018-0341-x.
Title:	Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation.
Author:	Chang, Tung-Cheng\|Chin, Yu-Tang\|Nana, Andre Wendindonde\|Wang, Shwu-Huey\|Liao, Yu-Min\|Chen, Yi-Ru\|Shih, Ya-Jung\|Changou, Chun A\|Yang, Yu-Chen Sh\|Wang, Kuan\|Whang-Peng, Jacqueline\|Wang, Liang-Shun\|Stain, Steven C\|Shih, Ai\|Lin, Hung-Yun\|Wu, Chih-Hsiung\|Davis
PMID:	30187356

2721.
Journal:	Int J Cancer. 2018 Sep 8.
Title:	PDEdelta inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas.
Author:	Klein, Christian H\|Truxius, Dina C\|Vogel, Holger A\|Harizanova, Jana\|Murarka, Sandip\|Martin-Gago, Pablo\|Bastiaens, Philippe I H
PMID:	30194764

2722.
Journal:	J Cell Physiol. 2018 Sep 10.
Title:	Neratinib augments the lethality of [regorafenib + sildenafil].
Author:	Booth, Laurence\|Roberts, Jane L\|Rais, Rumeesa\|Cutler, Richard E Jr\|Diala, Irmina\|Lalani, Alshad S\|Hancock, John F\|Poklepovic, Andrew\|Dent, Paul
PMID:	30203445

2723.
Journal:	Am J Transl Res. 2018 Aug 15;10(8):2402-2412. eCollection 2018.
Title:	Extracellular galectin-3 facilitates colon cancer cell migration and is related to the epidermal growth factor receptor.
Author:	Wu, Keng-Liang\|Kuo, Chung-Mou\|Huang, Eng-Yen\|Pan, Hui-Mei\|Huang, Chao-Cheng\|Chen, Yi-Fan\|Hsiao, Chang-Chun\|Yang, Kuender D
PMID:	30210679

2724.
Journal:	Int J Nanomedicine. 2018 Aug 31;13:4961-4975.
Title:	Anti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal cancer treatment.
Author:	Zhang, Zhen\|Qian, Hanqing\|Huang, Jie\|Sha, Huizi\|Zhang, Hang\|Yu, Lixia\|Liu, Baorui\|Hua, Dong\|Qian, Xiaoping
PMID:	30214200

2725.
Journal:	Future Oncol. 2018 Sep 14.
Title:	Pre-emptive skin treatments to prevent skin toxicity caused by anti-EGFR antibody: the real-world evidence in Japan.
Author:	Yamazaki, Naoya\|Oomuku, Yumi\|Mishiro, Izumi\|Soeda, Junpei
PMID:	30215532

2726.
Journal:	Adv Ther. 2018 Sep 14. pii: 10.1007/s12325-018-0791-0.
Title:	An Update of Efficacy and Safety of Cetuximab in Metastatic Colorectal Cancer: A Narrative Review.
Author:	Fornasier, Giulia\|Francescon, Sara\|Baldo, Paolo
PMID:	30218345

2727.
Journal:	Oncol Rep. 2018 Nov;40(5):2690-2697.
Title:	EGF ligand fused to truncated Pseudomonas aeruginosa exotoxin A specifically targets and inhibits EGFRpositive cancer cells.
Author:	Hashimi, Saeed M\|Grant, Brock\|Alqurashi, Naif\|Alowaidi, Faisal\|Wei, Ming Q
PMID:	30226622

2728.
Journal:	Am Soc Clin Oncol Educ Book. 2018 May 23;(38):978-997.
Title:	Liquid Biopsy to Identify Actionable Genomic Alterations.
Author:	Ou, Sai-Hong Ignatius\|Nagasaka, Misako\|Zhu, Viola W
PMID:	30231331

2729.
Journal:	Arab J Gastroenterol. 2018 Sep 20. pii: S1687-1979(18)30064-9.
Title:	Expression of epidermal growth factor receptor (EGFR) in colorectal cancer: An immunohistochemical study.
Author:	Ben Brahim, Ehsen\|Ayari, Imen\|Jouini, Raja\|Atafi, Salsabil\|Koubaa, Wafa\|Elloumi, Hela\|Chadli, Aschraf
PMID:	30243897

2730.
Journal:	Am J Pathol. 2018 Sep 21. pii: S0002-9440(18)30279-7.
Title:	Expression of Lrig1, a negative regulator of EGFR, is dynamically altered during different stages of gastric carcinogenesis.
Author:	Yu, Sungsook\|Yang, Mijeong\|Lim, Kyung-Min\|Cho, Yejin\|Kim, Hyunji\|Lee, Keunwook\|Jeong, Sang-Ho\|Coffey, Robert J\|Goldenring, James R\|Nam, Ki Taek
PMID:	30248341

2731.
Journal:	Int J Cancer. 2018 Sep 25.
Title:	Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.
Author:	Bormann, Felix\|Stinzing, Sebastian\|Tierling, Sascha\|Morkel, Markus\|Rivera Markelova, Maria\|Walter, Jorn\|Weichert, Wilko\|Rossner, Florian\|Kuhn, Natalia\|Perner, Juliane\|Dietz, Johanna\|Ispasanie, Sylvia\|Dietel, Manfred\|Schafer, Reinhold\|Heinemann, Volker\|Ser
PMID:	30252132

2732.
Journal:	Cancers (Basel). 2018 Sep 26;10(10). pii: cancers10100355.
Title:	A Novel Role for the Interleukin-1 Receptor Axis in Resistance to Anti-EGFR Therapy.
Author:	Gelfo, Valerio\|Mazzeschi, Martina\|Grilli, Giada\|Lindzen, Moshit\|Santi, Spartaco\|D'Uva, Gabriele\|Gyorffy, Balazs\|Ardizzoni, Andrea\|Yarden, Yosef\|Lauriola, Mattia
PMID:	30261609

2733.
Journal:	Cancer Med. 2018 Sep 27.
Title:	The anti-metastatic effect of ginsenoside Rb2 in colorectal cancer in an EGFR/SOX2-dependent manner.
Author:	Phi, Lan Thi Hanh\|Wijaya, Yoseph Toni\|Sari, Ita Novita\|Yang, Ying-Gui\|Lee, Yun Kyung\|Kwon, Hyog Young
PMID:	30264477

2734.
Journal:	Anticancer Res. 2018 Oct;38(10):5983-5990.
Title:	EGFR, SMAD7, and TGFBR2 Polymorphisms Are Associated with Colorectal Cancer in Patients with Lynch Syndrome.
Author:	Kamiza, Abram Bunya\|Wang, Wen-Chang\|You, Jeng-Fu\|Tang, Reiping\|Wang, Yen-Ting\|Chien, Huei-Tzu\|Lai, Chih-Hsiung\|Chiu, Li-Ling\|Lo, Tsai-Ping\|Hung, Kuan-Yi\|Hsiung, Chao Agnes\|Yeh, Chih-Ching
PMID:	30275229

2735.
Journal:	BMC Cancer. 2018 Oct 5;18(1):957.
Title:	Oral mucositis associated with anti-EGFR therapy in colorectal cancer: single institutional retrospective cohort study.
Author:	Dote, Satoshi\|Itakura, Shoji\|Kamei, Kohei\|Hira, Daiki\|Noda, Satoshi\|Kobayashi, Yuka\|Terada, Tomohiro
PMID:	30290786

2736.
Journal:	Int J Cancer. 2018 Oct 10.
Title:	ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in Early Stage Gallbladder Cancer.
Author:	Iyer, Prajish\|Shrikhande, Shailesh V\|Ranjan, Malika\|Joshi, Asim\|Gardi, Nilesh\|Prasad, Ratnam\|Dharavath, Bhasker\|Thorat, Rahul\|Salunkhe, Sameer\|Sahoo, Bikram\|Chandrani, Pratik\|Kore, Hitesh\|Mohanty, Bhabani\|Chaudhari, Vikram\|Choughule, Anuradha\|Kawle, Dhana
PMID:	30304546

2737.
Journal:	Oncotarget. 2018 Sep 11;9(71):33446-33458.
Title:	RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models.
Author:	Wong, Oi Kwan\|Tran, Thomas-Toan\|Ho, Wei-Hsien\|Casas, Meritxell Galindo\|Au, Melinda\|Bateman, Marjorie\|Lindquist, Kevin C\|Rajpal, Arvind\|Shelton, David L\|Strop, Pavel\|Liu, Shu-Hui
PMID:	30323890

2738.
Journal:	Oncol Lett. 2018 Nov;16(5):6188-6194.
Title:	EPA significantly improves anti-EGFR targeted therapy by regulating miR-378 expression in colorectal cancer.
Author:	Weng, Wen-Hui\|Leung, Wai-Hung\|Pang, Yeu Jye\|Kuo, Li-Wei\|Hsu, Hsi-Hsien
PMID:	30333883

2739.
Journal:	Ther Drug Monit. 2018 Oct 16.
Title:	Circulating cell-free DNA- diagnostic and prognostic applications in personalized cancer therapy.
Author:	Oellerich, M\|Schutz, E\|Beck, J\|Walson, P D
PMID:	30335711

2740.
Journal:	Oncotarget. 2018 Sep 28;9(76):34279-34288.
Title:	Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.
Author:	Del Carmen, Sofia\|Sayagues, Jose Maria\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Alcazar, Jose Antonio\|Gervas, Ruth\|Garcia, Jacinto\|Orfao, Alberto\|Bellvis, Luis Munoz\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria
PMID:	30344942

2741.
Journal:	F1000Res. 2018 Sep 24;7.
Title:	Recent advances in understanding colorectal cancer.
Author:	Stintzing, Sebastian
PMID:	30345013

2742.
Journal:	Target Oncol. 2018 Oct 23. pii: 10.1007/s11523-018-0597-7.
Title:	Impact of Delayed Addition of Anti-EGFR Monoclonal Antibodies on the Outcome of First-Line Therapy in Metastatic Colorectal Cancer Patients: a Retrospective Registry-Based Analysis.
Author:	Fiala, Ondrej\|Veskrnova, Veronika\|Chloupkova, Renata\|Poprach, Alexandr\|Kiss, Igor\|Kopeckova, Katerina\|Dusek, Ladislav\|Slavicek, Lubomir\|Kohoutek, Milan\|Finek, Jindrich\|Svoboda, Marek\|Petruzelka, Lubos\|Boublikova, Ludmila\|Dvorak, Josef\|Melichar, Bohuslav\|B
PMID:	30353488

2743.
Journal:	J BUON. 2018 Jul-Aug;23(4):925-935.
Title:	Worst outcomes according to RAS mutation variants: an analysis in patients with metastatic colorectal adenocarcinoma.
Author:	Uson, Pedro L S Jr\|Bugano, Diogo D G\|Moura, Fernando\|Carvalho, Ricardo S\|Maluf, Fernando C
PMID:	30358195