Primary Site >> Biliary tract Cancer

Gene >> EGFR

1.
Journal: Liver. 1988 Jun;8(3):157-66.
Title: Simultaneous detection of epidermal growth factor receptor (EGF-R), epidermal growth factor (EGF) and ras p21 in cholangiocarcinoma by an immunocytochemical method.
Author: Nonomura, A|Ohta, G|Nakanuma, Y|Izumi, R|Mizukami, Y|Matsubara, F|Hayashi, M|Watanabe, K|Takayanagi, N
PMID: 2839749
2.
Journal: Nihon Geka Gakkai Zasshi. 1990 Nov;91(11):1758.
Title: [Immunohistochemical study of epidermal growth factor receptor and c-erbB.2 oncogene product in bile duct carcinoma: preliminary report].
Author: Sasaki, R|Kanno, S|Toyoshima, H|Sudo, T|Abe, T|Saito, K|Tomichi, N
PMID: 1980521
3.
Journal: J Gastroenterol. 1994 Oct;29(5):616-20.
Title: Serum levels of c-erbB-2 protein in digestive diseases.
Author: Motoo, Y|Sawabu, N|Yamaguchi, Y|Mouri, I|Yamakawa, O|Watanabe, H|Ohta, H|Okai, T|Makino, H
PMID: 7528080
4.
Journal: Hum Pathol. 1994 Sep;25(9):964-5.
Title: Expression of epidermal growth factor receptor in gallbladder cancer.
Author: Valerdiz-Casasola, S
PMID: 8088775
5.
Journal: Pathol Res Pract. 1995 Nov;191(11):1087-91.
Title: Epidermal growth factor receptor immunoreactivity in gallbladder and extrahepatic biliary tract tumours.
Author: Lee, C S|Pirdas, A
PMID: 8822109
6.
Journal: Can J Surg. 1996 Jun;39(3):193-7.
Title: An animal model of benign bile-duct stricture, sclerosing cholangitis and cholangiocarcinoma and the role of epidermal growth factor receptor in ductal proliferation.
Author: Cheifetz, R E|Davis, N L|Owen, D A
PMID: 8640617
7.
Journal: J Pathol. 1996 Feb;178(2):140-5.
Title: Overexpression of different members of the type 1 growth factor receptor family and their association with cell proliferation in periampullary carcinoma.
Author: Vaidya, P|Kawarada, Y|Higashiguchi, T|Yoshida, T|Sakakura, T|Yatani, R
PMID: 8683379
8.
Journal: J Dermatol. 1996 Mar;23(3):191-5.
Title: Hereditary onset of multiple seborrheic keratoses: a variant of Leser Trelat sign?
Author: Yamamoto, T|Yokoyama, A
PMID: 8935630
9.
Journal: Eur J Surg Oncol. 1998 Feb;24(1):38-42.
Title: Transforming growth factor alpha immunoreactivity in human gallbladder and extrahepatic biliary tract tumours.
Author: Lee, C S
PMID: 9542514
10.
Journal: Histopathology. 1998 Oct;33(4):325-31.
Title: c-erbB-2 protein is expressed in hepatolithiasis and cholangiocarcinoma.
Author: Terada, T|Ashida, K|Endo, K|Horie, S|Maeta, H|Matsunaga, Y|Takashima, K|Ohta, T|Kitamura, Y
PMID: 9822921
11.
Journal: Pathol Res Pract. 2001;197(2):95-100.
Title: Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma.
Author: Ito, Y|Takeda, T|Sasaki, Y|Sakon, M|Yamada, T|Ishiguro, S|Imaoka, S|Tsujimoto, M|Higashiyama, S|Monden, M|Matsuura, N
PMID: 11261824
12.
Journal: Cancer Res. 2001 Oct 1;61(19):6971-6.
Title: Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma.
Author: Kiguchi, K|Carbajal, S|Chan, K|Beltran, L|Ruffino, L|Shen, J|Matsumoto, T|Yoshimi, N|DiGiovanni, J
PMID: 11585718
13.
Journal: Gastroenterology. 2002 Apr;122(4):985-93.
Title: Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line.
Author: Yoon, Jung-Hwan|Higuchi, Hajime|Werneburg, Nathan W|Kaufmann, Scott H|Gores, Gregory J
PMID: 11910351
14.
Journal: J Hepatol. 2002 Jun;36(6):780-5.
Title: Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry.
Author: Ukita, Yoko|Kato, Masako|Terada, Tadashi
PMID: 12044528
15.
Journal: Ai Zheng. 2003 Mar;22(3):262-5.
Title: [Significance of expression of epidermal growth factor (EGF) and its receptor (EGFR) in chronic cholecystitis and gallbladder carcinoma].
Author: Zhou, Yan-Ming|Li, Yu-Min|Cao, Nong|Feng, Ying|Zeng, Feng
PMID: 12654182
16.
Journal: Dig Liver Dis. 2003 May;35(5):332-8.
Title: Investigation of ErbB1 and ErbB2 expression for therapeutic targeting in primary liver tumours.
Author: Altimari, A|Fiorentino, M|Gabusi, E|Gruppioni, E|Corti, B|D'Errico, A|Grigioni, W F
PMID: 12846405
17.
Journal: Cancer Immunol Immunother. 2004 Jun;53(6):497-509. Epub 2003 Nov 25.
Title: A highly effective and stable bispecific diabody for cancer immunotherapy: cure of xenografted tumors by bispecific diabody and T-LAK cells.
Author: Hayashi, Hiroki|Asano, Ryutaro|Tsumoto, Kouhei|Katayose, Yu|Suzuki, Masanori|Unno, Michiaki|Kodama, Hideaki|Takemura, Shin-ichi|Yoshida, Hiroshi|Makabe, Koki|Imai, Kohzoh|Matsuno, Seiki|Kumagai, Izumi|Kudo, Toshio
PMID: 14648071
18.
Journal: Zhonghua Gan Zang Bing Za Zhi. 2004 Jan;12(1):55.
Title: [The expression and their significance of epidermal growth factor, transforming growth factor alpha and epidermal growth factor receptor during the intrahepatic cholangiocarcinoma carcinogenesis].
Author: Zhuang, Da-yong|Liang, Ping|Fan, Xi-hong|Chen, Hai
PMID: 14761293
19.
Journal: Ann Surg. 2004 Jul;240(1):89-94.
Title: Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: appraisal of an animal model of cholangiocarcinoma.
Author: Jan, Yi-Yin|Yeh, Ta-Sen|Yeh, Jun-Nan|Yang, Horng-Ren|Chen, Miin-Fu
PMID: 15213623
20.
Journal: J Hepatol. 2004 Nov;41(5):808-14.
Title: Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells.
Author: Yoon, Jung-Hwan|Gwak, Geum-Youn|Lee, Hyo-Suk|Bronk, Steven F|Werneburg, Nathan W|Gores, Gregory J
PMID: 15519654
21.
Journal: Liver Int. 2004 Dec;24(6):687-95.
Title: Imatinib mesylate induces apoptosis in human cholangiocarcinoma cells.
Author: Chiorean, Mihnea V|Guicciardi, Maria Eugenia|Yoon, Jung-Hwan|Bronk, Steven F|Kaufmanns, Scott H|Gores, Gregory J
PMID: 15566522
22.
Journal: Korean J Gastroenterol. 2005 Jan;45(1):52-9.
Title: [Expression of epidermal growth factor receptor, ErbB2 and matrix metalloproteinase-9 in hepatolithiasis and cholangiocarcinoma].
Author: Kim, Hyo Jung|Kim, Jae Seon|Kang, Chang Don|Lee, Sung Joon|Kim, Jin Yong|Yeon, Jong Eun|Park, Jong-Jae|Shim, Jae Jeong|Byun, Kwan Soo|Bak, Young-Tae|Lee, Chang Hong
PMID: 15665568
23.
Journal: Cancer Res. 2005 Apr 15;65(8):3003-10.
Title: Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents.
Author: Jimeno, Antonio|Rubio-Viqueira, Belen|Amador, Maria L|Oppenheimer, Darin|Bouraoud, Nadia|Kulesza, Peter|Sebastiani, Valeria|Maitra, Anirban|Hidalgo, Manuel
PMID: 15833824
24.
Journal: Biochim Biophys Acta. 2005 Jul 25;1755(2):135-50.
Title: Cyclooxygenase-2 and prostaglandin signaling in cholangiocarcinoma.
Author: Wu, Tong
PMID: 15921858
25.
Journal: J Cancer Res Clin Oncol. 2005 Oct;131(10):649-52. Epub 2005 Oct 20.
Title: Detection of response-predicting mutations in the kinase domain of the epidermal growth factor receptor gene in cholangiocarcinomas.
Author: Gwak, G-Y|Yoon, J-H|Shin, C M|Ahn, Y J|Chung, J K|Kim, Y A|Kim, T-Y|Lee, H-S
PMID: 16032426
26.
Journal: Clin Cancer Res. 2005 Aug 1;11(15):5572-80.
Title: Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma.
Author: Kiguchi, Kaoru|Ruffino, Lynnsie|Kawamoto, Toru|Ajiki, Tetsuo|Digiovanni, John
PMID: 16061875
27.
Journal: Hepatology. 2005 Sep;42(3):657-64.
Title: Characterization of intrahepatic cholangiocarcinoma of the intraductal growth-type and its precursor lesions.
Author: Yeh, Ta-Sen|Tseng, Jeng-Hwei|Chen, Tse-Ching|Liu, Nai-Jen|Chiu, Cheng-Tang|Jan, Yi-Yin|Chen, Miin-Fu
PMID: 16116640
28.
Journal: Cancer Res Treat. 2005 Jun;37(3):171-6.
Title: Co-expression of cox-2, C-met and beta-catenin in cells forming invasive front of gallbladder cancer.
Author: Moon, Woo Sung|Park, Ho Sung|Lee, Ho|Pai, Rama|Tarnawski, Andrzej S|Kim, Kyung Ryoul|Jang, Kyu Yun
PMID: 19956499
29.
Journal: Int J Oncol. 2006 Apr;28(4):915-21.
Title: The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
Author: Miyata, Hideki|Sasaki, Tamito|Kuwahara, Kenichi|Serikawa, Masahiro|Chayama, Kazuaki
PMID: 16525641
30.
Journal: Clin Cancer Res. 2006 Mar 15;12(6):1680-5.
Title: Somatic mutations of epidermal growth factor receptor in bile duct and gallbladder carcinoma.
Author: Leone, Francesco|Cavalloni, Giuliana|Pignochino, Ymera|Sarotto, Ivana|Ferraris, Renato|Piacibello, Wanda|Venesio, Tiziana|Capussotti, Lorenzo|Risio, Mauro|Aglietta, Massimo
PMID: 16551849
31.
Journal: Mol Cancer Ther. 2006 Jul;5(7):1895-903.
Title: Assessment of gefitinib- and CI-1040-mediated changes in epidermal growth factor receptor signaling in HuCCT-1 human cholangiocarcinoma by serial fine needle aspiration.
Author: Hidalgo, Manuel|Amador, Maria Luz|Jimeno, Antonio|Mezzadra, Heather|Patel, Pina|Chan, Audrey|Nielsen, Matthew E|Maitra, Anirban|Altiok, Soner
PMID: 16891476
32.
Journal: Anticancer Drugs. 2006 Aug;17(7):783-95.
Title: Novel targeted approaches to treating biliary tract cancer: the dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP-AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib.
Author: Wiedmann, Marcus|Feisthammel, Jurgen|Bluthner, Thilo|Tannapfel, Andrea|Kamenz, Thomas|Kluge, Annett|Mossner, Joachim|Caca, Karel
PMID: 16926628
33.
Journal: Cancer Res. 2006 Nov 1;66(21):10517-24.
Title: Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression.
Author: Wehbe, Hania|Henson, Roger|Meng, Fanyin|Mize-Berge, Janna|Patel, Tushar
PMID: 17079474
34.
Journal: Onkologie. 2007 Mar;30(3):129-31. Epub 2007 Feb 13.
Title: Effects of the anti-epidermal growth factor receptor antibody cetuximab on cholangiocarcinoma of the liver.
Author: Huang, Tsai-Wang|Wang, Chih-Hsin|Hsieh, Chung-Bao
PMID: 17341899
35.
Journal: Mol Cell Biochem. 2007 Nov;305(1-2):19-26. Epub 2007 Jun 6.
Title: Prostaglandin E2 enhances mitogen-activated protein kinase/Erk pathway in human cholangiocarcinoma cells: involvement of EP1 receptor, calcium and EGF receptors signaling.
Author: Zhang, Li|Jiang, Li|Sun, Qiuyan|Peng, Tao|Lou, Kexin|Liu, Ningbo|Leng, Jing
PMID: 17551669
36.
Journal: Mol Cancer Ther. 2007 Jun;6(6):1709-17.
Title: Therapeutic effect of CS-706, a specific cyclooxygenase-2 inhibitor, on gallbladder carcinoma in BK5.ErbB-2 mice.
Author: Kiguchi, Kaoru|Ruffino, Lynnsie|Kawamoto, Toru|Franco, Eugenia|Kurakata, Shin-ichi|Fujiwara, Kosaku|Hanai, Masaharu|Rumi, Mohammad|DiGiovanni, John
PMID: 17575102
37.
Journal: Hepatobiliary Pancreat Dis Int. 2007 Aug;6(4):412-5.
Title: Expression of c-erbB-2 proto-oncogene in extrahepatic cholangiocarcinoma and its clinical significance.
Author: Zheng, Jun|Zhu, Yao-Ming
PMID: 17690040
38.
Journal: Hepatogastroenterology. 2007 Jul-Aug;54(77):1339-44.
Title: Intestinal trefoil factor (TFF-3) and extracellular signal-regulated kinase (ERK) in cholangiocarcinoma.
Author: Ailawadhi, Sikander|Nagase, Hiroki|Khoury, Thaer|Yu, Jihnhee|Tan, Dongfeng|Black, Jennifer|Brattain, Michael|Javle, Milind
PMID: 17708250
39.
Journal: Oncology. 2007;72(1-2):105-10. Epub 2007 Nov 15.
Title: Cetuximab plus gemcitabine-oxaliplatin (GEMOX) in patients with refractory advanced intrahepatic cholangiocarcinomas.
Author: Paule, Bernard|Herelle, Marie-Olga|Rage, Estelle|Ducreux, Michel|Adam, Rene|Guettier, Catherine|Bralet, Marie-Pierre
PMID: 18025804
40.
Journal: Gastrointest Cancer Res. 2007 Nov;1(6):221-7.
Title: HER Receptor Family: Novel Candidate for Targeted Therapy for Gallbladder and Extrahepatic Bile Duct Cancer.
Author: Kawamoto, Toru|Krishnamurthy, Savitri|Tarco, Emily|Trivedi, Smita|Wistuba, Ignacio I|Li, Donghui|Roa, Ivan|Roa, Juan C|Thomas, Melanie B
PMID: 19262900
41.
Journal: Br J Cancer. 2008 Jan 29;98(2):418-25. Epub 2007 Dec 18.
Title: Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma.
Author: Yoshikawa, D|Ojima, H|Iwasaki, M|Hiraoka, N|Kosuge, T|Kasai, S|Hirohashi, S|Shibata, T
PMID: 18087285
42.
Journal: Curr Gastroenterol Rep. 2008 Feb;10(1):43-52.
Title: Diagnosis and management of cholangiocarcinoma.
Author: Sandhu, Dalbir S|Roberts, Lewis R
PMID: 18417042
43.
Journal: Int J Med Sci. 2008 Sep 22;5(5):285-91.
Title: EGFR expression in gallbladder carcinoma in North America.
Author: Kaufman, Matthew|Mehrotra, Bhoomi|Limaye, Sewanti|White, Sherrie|Fuchs, Alexander|Lebowicz, Yehuda|Nissel-Horowitz, Sandy|Thomas, Adrienne
PMID: 18825277
44.
Journal: World J Gastroenterol. 2008 Dec 14;14(46):7033-58.
Title: Role of ErbB family receptor tyrosine kinases in intrahepatic cholangiocarcinoma.
Author: Sirica, Alphonse-E
PMID: 19084911
45.
Journal: Oncology. 2009;76(4):293-300.
Title: A comprehensive analysis of immunohistochemical studies in intrahepatic cholangiocarcinoma using the survival tree model.
Author: Iguchi, Tomohiro|Yamashita, Natsumi|Aishima, Shinichi|Kuroda, Yousuke|Terashi, Takahiro|Sugimachi, Keishi|Taguchi, Ken-ichi|Taketomi, Akinobu|Maehara, Yoshihiko|Tsuneyoshi, Masazumi
PMID: 19262069
46.
Journal: Br J Cancer. 2009 Apr 21;100(8):1257-66.
Title: Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma.
Author: Yoshikawa, D|Ojima, H|Kokubu, A|Ochiya, T|Kasai, S|Hirohashi, S|Shibata, T
PMID: 19319137
47.
Journal: Anticancer Res. 2009 Jan;29(1):19-26.
Title: Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma.
Author: Ooi, Akishi|Suzuki, Shioto|Nakazawa, Kumiko|Itakura, Jun|Imoto, Issei|Nakamura, Hiroyuki|Dobashi, Yoh
PMID: 19331129
48.
Journal: Gastroenterology. 2009 Sep;137(3):1138-50, 1150.e1-9.
Title: ANXA8 down-regulation by EGF-FOXO4 signaling is involved in cell scattering and tumor metastasis of cholangiocarcinoma.
Author: Lee, Mi-Jin|Yu, Gyung-Ran|Yoo, Hee-Jung|Kim, Jong-Hyun|Yoon, Byung-Il|Choi, Yang-Kyu|Kim, Dae-Ghon
PMID: 19376120
49.
Journal: Anticancer Res. 2009 Apr;29(4):1169-80.
Title: ZD1839 (IRESSA) stabilizes p27Kip1 and enhances radiosensitivity in cholangiocarcinoma cell lines.
Author: Yabuuchi, Shinichi|Katayose, Yu|Oda, Akira|Mizuma, Masamichi|Shirasou, Satoru|Sasaki, Tsuyoshi|Yamamoto, Kuniharu|Oikawa, Masaya|Rikiyama, Toshiki|Onogawa, Tohru|Yoshida, Hiroshi|Ohtuska, Hideo|Motoi, Fuyuhiko|Egawa, Shinichi|Unno, Michiaki
PMID: 19414361
50.
Journal: Mol Cancer Ther. 2009 Jun;8(6):1547-56.
Title: Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells.
Author: Herberger, Beata|Berger, Walter|Puhalla, Harald|Schmid, Katharina|Novak, Sabine|Brandstetter, Anita|Pirker, Christine|Gruenberger, Thomas|Filipits, Martin
PMID: 19509244
51.
Journal: World J Gastroenterol. 2009 Sep 28;15(36):4511-7.
Title: EGFR and HER2 expression in advanced biliary tract cancer.
Author: Harder, Jan|Waiz, Oliver|Otto, Florian|Geissler, Michael|Olschewski, Manfred|Weinhold, Brigitte|Blum, Hubert E|Schmitt-Graeff, Annette|Opitz, Oliver G
PMID: 19777609
52.
Journal: Future Oncol. 2009 Dec;5(10):1675-84.
Title: Targeted therapy in biliary tract cancer: 2009 update.
Author: Tonini, Giuseppe|Virzi, Vladimir|Fratto, Maria Elisabetta|Vincenzi, Bruno|Santini, Daniele
PMID: 20001803
53.
Journal: Hum Pathol. 2010 Apr;41(4):485-92.
Title: Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder.
Author: Shafizadeh, Nafis|Grenert, James P|Sahai, Vaibhav|Kakar, Sanjay
PMID: 20040392
54.
Journal: Onkologie. 2010;33(1-2):45-7.
Title: Preliminary experience of cetuximab in the treatment of advanced-stage biliary tract cancer.
Author: Chang, Ping-Ying|Cheng, Ming-Fang|Lee, Herng-Sheng|Hsieh, Chung-Bao|Yao, Nai-Shun
PMID: 20164661
55.
Journal: Curr Drug Targets. 2010 Jul;11(7):834-50.
Title: Molecular targeted therapy of biliary tract cancer--results of the first clinical studies.
Author: Wiedmann, Marcus W|Mossner, Joachim
PMID: 20388063
56.
Journal: Eur Rev Med Pharmacol Sci. 2010 Apr;14(4):371-4.
Title: Chemotherapy in biliary tract cancer.
Author: Tonini, G|Frato, M E|Vincenzi, B|Santini, D
PMID: 20496551
57.
Journal: Hepatobiliary Pancreat Dis Int. 2010 Jun;9(3):325-8.
Title: Gallbladder cancer with tumor thrombus in the superior vena cava.
Author: Batra, Sandeep|Doval, Dinesh Chandra|Batra, Ullas|Suresh, Pandalanghat|Dhiman, Amit|Talwar, Vineet
PMID: 20525563
58.
Journal: J Clin Oncol. 2010 Jul 20;28(21):3491-7.
Title: Report of a multicenter phase II trial testing a combination of biweekly bevacizumab and daily erlotinib in patients with unresectable biliary cancer: a phase II Consortium study.
Author: Lubner, Sam J|Mahoney, Michelle R|Kolesar, Jill L|Loconte, Noelle K|Kim, George P|Pitot, Henry C|Philip, Philip A|Picus, Joel|Yong, Wei-Peng|Horvath, Lisa|Van Hazel, Guy|Erlichman, Charles E|Holen, Kyle D
PMID: 20530271
59.
Journal: BMC Cancer. 2010 Jun 18;10:302.
Title: Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines.
Author: Xu, Ling|Hausmann, Martin|Dietmaier, Wolfgang|Kellermeier, Silvia|Pesch, Theresa|Stieber-Gunckel, Manuela|Lippert, Elisabeth|Klebl, Frank|Rogler, Gerhard
PMID: 20565817
60.
Journal: Hepatology. 2010 Sep;52(3):975-86.
Title: Preclinical assessment of simultaneous targeting of epidermal growth factor receptor (ErbB1) and ErbB2 as a strategy for cholangiocarcinoma therapy.
Author: Zhang, Zichen|Oyesanya, Regina A|Campbell, Deanna J W|Almenara, Jorge A|Dewitt, Jennifer L|Sirica, Alphonse E
PMID: 20607690
61.
Journal: Ann Oncol. 2010 Oct;21 Suppl 7:vii345-8.
Title: Advances in the treatment of metastatic or unresectable biliary tract cancer.
Author: Valle, J W
PMID: 20943640
62.
Journal: BMC Cancer. 2010 Oct 20;10:570.
Title: Complete response in gallbladder cancer to erlotinib plus gemcitabine does not require mutation of the epidermal growth factor receptor gene: a case report.
Author: Mody, Kabir|Strauss, Edward|Lincer, Robert|Frank, Richard C
PMID: 20961434
63.
Journal: Eur J Surg Oncol. 2011 Jan;37(1):80-6.
Title: The prognostic relevance of tumor hypoxia markers in resected carcinoma of the gallbladder.
Author: Sergeant, G|Lerut, E|Ectors, N|Hendrickx, T|Aerts, R|Topal, B
PMID: 21109386
64.
Journal: PLoS One. 2011 Jan 6;6(1):e15640.
Title: Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma.
Author: Gu, Ting-Lei|Deng, Xiaxing|Huang, Feizhou|Tucker, Meghan|Crosby, Katherine|Rimkunas, Victoria|Wang, Yi|Deng, Gang|Zhu, Lei|Tan, Zhiping|Hu, Yerong|Wu, Chunlin|Nardone, Julie|MacNeill, Joan|Ren, Jianmin|Reeves, Cynthia|Innocenti, Gregory|Norris, Brett|Yuan
PMID: 21253578
65.
Journal: World J Gastroenterol. 2011 Mar 28;17(12):1631-41.
Title: Trefoil factors: tumor progression markers and mitogens via EGFR/MAPK activation in cholangiocarcinoma.
Author: Kosriwong, Kanuengnuch|Menheniott, Trevelyan R|Giraud, Andrew S|Jearanaikoon, Patcharee|Sripa, Banchob|Limpaiboon, Temduang
PMID: 21472131
66.
Journal: Semin Liver Dis. 2011 May;31(2):173-87.
Title: Genetics of hepatobiliary carcinogenesis.
Author: Nault, Jean-Charles|Zucman-Rossi, Jessica
PMID: 21538283
67.
Journal: Oncol Rep. 2011 Aug;26(2):315-20.
Title: Clinical relevance of epidermal growth factor receptor (EGFR) alterations in human pancreatic tumors.
Author: Lozano-Leon, Antonio|Perez-Quintela, Begona Vieites|Iglesias-Garcia, Julio|Urisarri-Ruiz, Adela|Larino-Noia, Jose|Abdulkader, Ihab|Varo, Evaristo|Forteza, Jeronimo|Dominguez-Munoz, J Enrique
PMID: 21573507
68.
Journal: Br J Cancer. 2011 Jun 28;105(1):131-8.
Title: Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma.
Author: Miyamoto, M|Ojima, H|Iwasaki, M|Shimizu, H|Kokubu, A|Hiraoka, N|Kosuge, T|Yoshikawa, D|Kono, T|Furukawa, H|Shibata, T
PMID: 21673683
69.
Journal: Ann Surg Oncol. 2012 Feb;19(2):443-54.
Title: EGFR nuclear import in gallbladder carcinoma: nuclear phosphorylated EGFR upregulates iNOS expression and confers independent prognostic impact.
Author: Li, Chien-Feng|Fang, Fu-Ming|Wang, Ju-Ming|Tzeng, Ching-Cherng|Tai, Hui-Chun|Wei, Yu-Ching|Li, Shau-Hsuan|Lee, Yuan-Ting|Wang, Yu-Hui|Yu, Shih-Chen|Shiue, Yow-Ling|Chu, Patrick Yu-Wei|Wang, Wen-Ling|Chen, Li-Tzong|Huang, Hsuan-Ying
PMID: 21761100
70.
Journal: Cancer Lett. 2012 Mar;316(1):70-6.
Title: L1 cell adhesion molecule and epidermal growth factor receptor activation confer cisplatin resistance in intrahepatic cholangiocarcinoma cells.
Author: Yoon, Hyunho|Min, Jeong-Ki|Lee, Dong Gwang|Kim, Dae-Ghon|Koh, Sang Seok|Hong, Hyo Jeong
PMID: 22088438
71.
Journal: Gastroenterology. 2012 Apr;142(4):1021-1031.e15.
Title: Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors.
Author: Andersen, Jesper B|Spee, Bart|Blechacz, Boris R|Avital, Itzhak|Komuta, Mina|Barbour, Andrew|Conner, Elizabeth A|Gillen, Matthew C|Roskams, Tania|Roberts, Lewis R|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 22178589
72.
Journal: Oncologist. 2012;17(1):13.
Title: Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101.
Author: Chiorean, E Gabriela|Ramasubbaiah, Rashmi|Yu, Menggang|Picus, Joel|Bufill, Jose A|Tong, Yan|Coleman, Nicki|Johnston, Erica L|Currie, Colleen|Loehrer, Patrick J
PMID: 22210086
73.
Journal: J Gastrointest Surg. 2012 Apr;16(4):842-8.
Title: Expression of matrix metalloproteinase-7 is an unfavorable prognostic factor in intrahepatic cholangiocarcinoma.
Author: Hirashita, Teijiro|Iwashita, Yukio|Ohta, Masayuki|Komori, Yoko|Eguchi, Hidetoshi|Yada, Kazuhiro|Kitano, Seigo
PMID: 22246855
74.
Journal: Hepatogastroenterology. 2012 Jun;59(116):1241-4.
Title: Clinicopathological significance of E-cadherin, beta-catenin and epidermal growth factor receptor expression in intrahepatic cholangiocarcinoma.
Author: Gu, Mi Jin|Choi, Joon Hyuk
PMID: 22281980
75.
Journal: BMC Cancer. 2012 May 16;12:179.
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Title: Obstructive jaundice caused by intraductal metastasis of lung adenocarcinoma.
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Title: Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications.
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Title: Bile acid accelerates erbB2-induced pro-tumorigenic activities in biliary tract cancer.
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Title: Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy.
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Title: Molecular Subgroup Analysis of Clinical Outcomes in a Phase 3 Study of Gemcitabine and Oxaliplatin with or without Erlotinib in Advanced Biliary Tract Cancer.
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Title: MicroRNA-146b-5p inhibits the growth of gallbladder carcinoma by targeting epidermal growth factor receptor.
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Title: Breast tumor kinase/protein tyrosine kinase 6 (Brk/PTK6) activity in normal and neoplastic biliary epithelia.
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Title: Taurolithocholic acid promotes intrahepatic cholangiocarcinoma cell growth via muscarinic acetylcholine receptor and EGFR/ERK1/2 signaling pathway.
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Title: Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2).
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Title: Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats.
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Title: Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases.
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Title: Cholangiocarcinoma: Correlation between Molecular Profiling and Imaging Phenotypes.
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Title: Predictive and prognostic molecular markers for cholangiocarcinoma in Han Chinese population.
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Title: Complete Response to Erlotinib and Bevacizumab in a Patient With Biphenotypic (Hepatobiliary) Primary Liver Carcinoma.
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Journal: Cytotechnology. 2016 Jan;68(1):123-33.
Title: Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway.
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Title: Molecular Pathogenesis and Targeted Therapies for Intrahepatic Cholangiocarcinoma.
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Title: Panitumumab in combination with gemcitabine and oxaliplatin does not prolong survival in wild-type KRAS advanced biliary tract cancer: A randomized phase 2 trial (Vecti-BIL study).
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Title: Genomics of gallbladder cancer: the case for biomarker-driven clinical trial design.
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Title: Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation.
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Title: EGFR, COX2, p-AKT expression and PIK3CA mutation in distal extrahepatic bile duct carcinoma.
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Title: The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets.
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Title: Expression levels of ROS1/ALK/c-MET and therapeutic efficacy of cetuximab plus chemotherapy in advanced biliary tract cancer.
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Title: The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
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Title: TACTIC: a multicentre, open-label, single-arm phase II trial of panitumumab, cisplatin, and gemcitabine in biliary tract cancer.
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Title: Epidermal growth factor receptor expression in carcinoma gallbladder: A prospective study in Indian scenario.
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Title: Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line.
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Title: KRAS Mutation as a Potential Prognostic Biomarker of Biliary Tract Cancers.
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Title: Whole-genome sequencing reveals the mutational landscape of metastatic small-cell gallbladder neuroendocrine carcinoma (GB-SCNEC).
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Journal: Onco Targets Ther. 2017 Feb 22;10:1131-1142.
Title: Intrahepatic cholangiocarcinoma: current perspectives.
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Title: The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer.
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Title: Efficacy and safety of chemotherapy with or without targeted therapy in biliary tract cancer: A meta-analysis of 7 randomized controlled trials.
Author: Zhuang, Xin|Xiao, Ya-Ping|Tan, Ling-Hua|Wang, Lu-Ting|Cao, Qian|Qu, Gui-Fang|Xiao, Shuang|Duan, Hua-Xin
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Journal: Am J Cancer Res. 2017 Mar 1;7(3):688-699. eCollection 2017.
Title: Integrated mRNA and lncRNA expression profiling for exploring metastatic biomarkers of human intrahepatic cholangiocarcinoma.
Author: Lv, Lisheng|Wei, Miaoyan|Lin, Peiyi|Chen, Zhisheng|Gong, Peng|Quan, Zhiwei|Tang, Zhaohui
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Journal: Oncotarget. 2017 Apr 18;8(16):26169-26184.
Title: Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
Author: Weber, Helga|Valbuena, Jose R|Barbhuiya, Mustafa A|Stein, Stefan|Kunkel, Hana|Garcia, Patricia|Bizama, Carolina|Riquelme, Ismael|Espinoza, Jaime A|Kurtz, Stephen E|Tyner, Jeffrey W|Calderon, Juan Francisco|Corvalan, Alejandro H|Grez, Manuel|Pandey, Akhile
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Journal: Tumour Biol. 2017 May;39(5):1010428317698359.
Title: Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway.
Author: Zhang, Mingdi|Cai, Shizhong|Zuo, Bin|Gong, Wei|Tang, Zhaohui|Zhou, Di|Weng, Mingzhe|Qin, Yiyu|Wang, Shouhua|Liu, Jun|Ma, Fei|Quan, Zhiwei
PMID: 28459363
147.
Journal: Cancer Lett. 2017 Sep 10;403:66-73.
Title: Claudin-18 coupled with EGFR/ERK signaling contributes to the malignant potentials of bile duct cancer.
Author: Takasawa, Kumi|Takasawa, Akira|Osanai, Makoto|Aoyama, Tomoyuki|Ono, Yusuke|Kono, Tsuyoshi|Hirohashi, Yoshihiko|Murata, Masaki|Sawada, Norimasa
PMID: 28624624
148.
Journal: Hepatology. 2017 Jul 3.
Title: Role of ErbB/HER family of receptor tyrosine kinases in cholangiocyte biology.
Author: Pellat, Anna|Vaquero, Javier|Fouassier, Laura
PMID: 28671339
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Journal: Sci Rep. 2017 Jul 20;7(1):5982.
Title: Therapeutic effects of long-circulating miR-135a-containing cationic immunoliposomes against gallbladder carcinoma.
Author: Yang, Guanghua|Yin, Baobing
PMID: 28729631
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Journal: J Gastrointest Oncol. 2017 Jun;8(3):430-440.
Title: Current biologics for treatment of biliary tract cancers.
Author: Zhao, Diana Y|Lim, Kian-Huat
PMID: 28736630
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Journal: J Virol. 2017 Sep 27;91(20). pii: JVI.00467-17.
Title: HRAS, EGFR, MET, and RON Genes Are Recurrently Activated by Provirus Insertion in Liver Tumors Induced by the Retrovirus Myeloblastosis-Associated Virus 2.
Author: Pecenka, Vladimir|Pajer, Petr|Karafiat, Vit|Kasparova, Petra|Dudlova, Jana|Dvorak, Michal
PMID: 28768863
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Journal: Cancer Med. 2017 Sep;6(9):2042-2051.
Title: INST OX-05-024: first line gemcitabine, oxaliplatin, and erlotinib for primary hepatocellular carcinoma and bile duct cancers: a multicenter Phase II trial.
Author: Patt, Yehuda Z|Murad, Waheed|Fekrazad, Mohammed H|Baron, Ari D|Bansal, Pranshu|Boumber, Yanis|Steinberg, Kim|Lee, Sang-Joon|Bedrick, Ed|Du, Ruofei|Lee, Fa Chyi
PMID: 28801995
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Journal: Pathology. 2017 Oct;49(6):582-588.
Title: Gene copy number variation and protein overexpression of EGFR and HER2 in distal extrahepatic cholangiocarcinoma.
Author: Jung, Min Jung|Woo, Chang Gok|Lee, Saetbyeol|Chin, Susie|Kim, Hee Kyung|Kwak, Jeong Ja|Koh, Eun Suk|Lee, Bora|Jang, Kee-Taek|Moon, Ahrim
PMID: 28843919
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Journal: Ecancermedicalscience. 2017 Aug 7;11:757.
Title: Mutational frequency of KRAS, NRAS, IDH2, PIK3CA, and EGFR in North Indian gallbladder cancer patients.
Author: Sharma, Aarti|Kumar, Ashok|Kumari, Niraj|Krishnani, Narendra|Rastogi, Neeraj
PMID: 28900470
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Journal: Cancer Control. 2017 Jul-Sep;24(3):1073274817729241.
Title: Systemic and Adjuvant Therapies for Intrahepatic Cholangiocarcinoma.
Author: Chun, Yun Shin|Javle, Milind
PMID: 28975832
156.
Journal: Clin Cancer Res. 2018 Mar 15;24(6):1277-1286.
Title: Phase I Study of Chimeric Antigen Receptor-Modified T Cells in Patients with EGFR-Positive Advanced Biliary Tract Cancers.
Author: Guo, Yelei|Feng, Kaichao|Liu, Yang|Wu, Zhiqiang|Dai, Hanren|Yang, Qingming|Wang, Yao|Jia, Hejin|Han, Weidong
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157.
Journal: PLoS One. 2018 Jan 19;13(1):e0191593.
Title: Prognostic and predictive role of EGFR pathway alterations in biliary cancer patients treated with chemotherapy and anti-EGFR.
Author: Peraldo-Neia, Caterina|Cavalloni, Giuliana|Fenocchio, Elisabetta|Cagnazzo, Celeste|Gammaitoni, Loretta|Cereda, Stefano|Nasti, Guglielmo|Satolli, Maria Antonietta|Aprile, Giuseppe|Reni, Michele|Avallone, Antonio|Spadi, Rosella|Venesio, Tiziana|Martin, Vitt
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Journal: Eur J Cancer. 2018 Mar;92:11-19.
Title: PICCA study: panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer-a randomised biomarker-driven clinical phase II AIO study.
Author: Vogel, Arndt|Kasper, Stefan|Bitzer, Michael|Block, Andreas|Sinn, Marianne|Schulze-Bergkamen, Henning|Moehler, Markus|Pfarr, Nicole|Endris, Volker|Goeppert, Benjamin|Merx, Kirsten|Schnoy, Elisabeth|Siveke, Jens T|Michl, Patrick|Waldschmidt, Dirk|Kuhlmann,
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Journal: Am J Cancer Res. 2018 Jan 1;8(1):2-15. eCollection 2018.
Title: Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers.
Author: Papadopoulou, Kyriaki|Murray, Samuel|Manousou, Kyriaki|Tikas, Ioannis|Dervenis, Christos|Sgouros, Joseph|Rontogianni, Dimitra|Lakis, Sotirios|Bobos, Mattheos|Poulios, Christos|Pervana, Stavroula|Lazaridis, Georgios|Fountzilas, George|Kotoula, Vassiliki
PMID: 29416916
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Journal: J Hepatol. 2018 Jul;69(1):89-98.
Title: Spatial and temporal clonal evolution of intrahepatic cholangiocarcinoma.
Author: Dong, Liang-Qing|Shi, Yang|Ma, Li-Jie|Yang, Liu-Xiao|Wang, Xiao-Ying|Zhang, Shu|Wang, Zhi-Chao|Duan, Meng|Zhang, Zhao|Liu, Long-Zi|Zheng, Bo-Hao|Ding, Zhen-Bin|Ke, Ai-Wu|Gao, Da-Ming|Yuan, Ke|Zhou, Jian|Fan, Jia|Xi, Ruibin|Gao, Qiang
PMID: 29551704
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Journal: J Gastrointest Oncol. 2018 Feb;9(1):111-125.
Title: Investigation of targetable predictive and prognostic markers in gallbladder carcinoma.
Author: Neyaz, Azfar|Husain, Nuzhat|Gupta, Sameer|Kumari, Swati|Arora, Aditi|Awasthi, Namrata Puneet|Malhotra, Kiran Preet|Misra, Sanjeev
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Journal: J Cancer Res Ther. 2018;14(Supplement):S28-S35.
Title: Human epidermal growth factor receptor 2, epidermal growth factor receptor, and c-MET overexpression and survival in biliary tract cancer: A meta-analysis.
Author: Zhou, Wei|Jiang, Congqing|Zhan, Nan|Lv, Xiaoguang|Fan, Lifang|Ninu, Maskey
PMID: 29578146
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Journal: Hum Pathol. 2018 Aug;78:131-137.
Title: Mucinous intrahepatic cholangiocarcinoma: a distinct variant.
Author: Chi, Zhikai|Bhalla, Amarpreet|Saeed, Omer|Cheng, Liang|Curless, Kendra|Wang, Hanlin L|Patil, Deepa T|Lin, Jingmei
PMID: 29698701
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Journal: J Cancer. 2018 Apr 6;9(8):1476-1485.
Title: EGFR Target Therapy Combined with Gemox for Advanced Biliary Tract Cancers: a Meta-analysis based on RCTs.
Author: Cai, Wen|Yuan, Ying|Ge, Weiting|Fan, Yu|Liu, Xue|Wu, Dehao|Hu, Hanguang
PMID: 29721058
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Journal: Exp Ther Med. 2018 Jun;15(6):4995-5000.
Title: Blocking of the EGFR-STAT3 signaling pathway through afatinib treatment inhibited the intrahepatic cholangiocarcinoma.
Author: Zhang, Changhe|Xu, Hong|Zhou, Zhenping|Tian, Ye|Cao, Xiaofei|Cheng, Guochang|Liu, Qinghong
PMID: 29805522
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Journal: Gut. 2018 Jun 28. pii: gutjnl-2018-316039.
Title: Genomic ERBB2/ERBB3 mutations promote PD-L1-mediated immune escape in gallbladder cancer: a whole-exome sequencing analysis.
Author: Li, Maolan|Liu, Fatao|Zhang, Fei|Zhou, Weiping|Jiang, Xiaoqing|Yang, Yuan|Qu, Kai|Wang, Yueqi|Ma, Qiang|Wang, Ting|Bai, Lu|Wang, Zheng|Song, Xiaoling|Zhu, Yidi|Yuan, Ruiyan|Gao, Yuan|Liu, Yongchen|Jin, Yunpeng|Li, Huaifeng|Xiang, Shanshan|Ye, Yuanyuan|Zha
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Journal: Int J Cancer. 2018 Oct 10.
Title: ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in Early Stage Gallbladder Cancer.
Author: Iyer, Prajish|Shrikhande, Shailesh V|Ranjan, Malika|Joshi, Asim|Gardi, Nilesh|Prasad, Ratnam|Dharavath, Bhasker|Thorat, Rahul|Salunkhe, Sameer|Sahoo, Bikram|Chandrani, Pratik|Kore, Hitesh|Mohanty, Bhabani|Chaudhari, Vikram|Choughule, Anuradha|Kawle, Dhana
PMID: 30304546