Primary Site >> Colorectal Cancer

Gene >> CYP2C8

Journal: Cancer Chemother Pharmacol. 2005 Sep;56(3):248-54. Epub 2005 Apr 27.
Title: P450 induction alters paclitaxel pharmacokinetics and tissue distribution with multiple dosing.
Author: Gustafson, Daniel L|Long, Michael E|Bradshaw, Erica L|Merz, Andrea L|Kerzic, Patrick J
PMID: 15856231
Journal: Pharmacogenet Genomics. 2005 Oct;15(10):713-21.
Title: No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARdelta and PPARgamma act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma.
Author: McGreavey, Louise E|Turner, Faye|Smith, Gillian|Boylan, Katherine|Timothy Bishop, D|Forman, David|Roland Wolf, C|Barrett, Jennifer H
PMID: 16141797
Journal: Pharmacogenomics. 2006 Jun;7(4):575-85.
Title: Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8.
Author: Garcia-Martin, Elena|Pizarro, Rosa M|Martinez, Carmen|Gutierrez-Martin, Yolanda|Perez, Gabriela|Jover, Ramiro|Agundez, Jose Ag
PMID: 16753005
Journal: Front Genet. 2012 Dec 3;3:278.
Title: Analysis of the Functional Polymorphism in the Cytochrome P450 CYP2C8 Gene rs11572080 with Regard to Colorectal Cancer Risk.
Author: Ladero, Jose M|Agundez, Jose A G|Martinez, Carmen|Amo, Gemma|Ayuso, Pedro|Garcia-Martin, Elena
PMID: 23420707
Journal: Oncotarget. 2018 Jan 10;9(10):9043-9060.
Title: Analysis of a gene panel for targeted sequencing of colorectal cancer samples.
Author: Jensen, Klaus Hojgaard|Izarzugaza, Jose M G|Juncker, Agnieszka Sierakowska|Hansen, Rasmus Borup|Hansen, Torben Frostrup|Timshel, Pascal|Blondal, Thorarinn|Jensen, Thomas Skot|Rygaard-Hjalsted, Eske|Mouritzen, Peter|Thorsen, Michael|Wernersson, Rasmus|Niel
PMID: 29507673