Primary Site >> Biliary tract Cancer

Gene >> CXCR4

Journal: Am J Pathol. 2006 Apr;168(4):1155-68.
Title: Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factor-alpha and stromal-derived factor-1 released in stroma.
Author: Ohira, Shusaku|Sasaki, Motoko|Harada, Kenichi|Sato, Yasunori|Zen, Yoh|Isse, Kumiko|Kozaka, Kazuto|Ishikawa, Akira|Oda, Koji|Nimura, Yuji|Nakanuma, Yasuni
PMID: 16565491
Journal: World J Gastroenterol. 2007 Mar 14;13(10):1561-8.
Title: Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
Author: Leelawat, Kawin|Leelawat, Surang|Narong, Siriluck|Hongeng, Suradej
PMID: 17461449
Journal: J Int Med Res. 2011;39(4):1253-64.
Title: High expression of CXCR4 and CXCR7 predicts poor survival in gallbladder cancer.
Author: Yao, X|Zhou, L|Han, S|Chen, Y
PMID: 21986127
Journal: Clin Cancer Res. 2012 Jun 15;18(12):3270-80.
Title: Chemokine (C-X-C motif) ligand 12 is associated with gallbladder carcinoma progression and is a novel independent poor prognostic factor.
Author: Lee, Hyun Jung|Lee, Kyungmin|Lee, Dong Gwang|Bae, Kwang-Hee|Kim, Jang-Seong|Liang, Zhe Long|Huang, Song Mei|Suk Oh, Yoon|Kim, Ha Yon|Jo, Deog Yeon|Min, Jeong-Ki|Kim, Jin-Man|Lee, Hyo Jin
PMID: 22553346
Journal: Int J Oncol. 2012 Aug;41(2):573-82.
Title: Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma.
Author: Okamoto, Koichi|Tajima, Hidehiro|Nakanuma, Shinichi|Sakai, Seisho|Makino, Isamu|Kinoshita, Jun|Hayashi, Hironori|Nakamura, Keishi|Oyama, Katsunobu|Nakagawara, Hisatoshi|Fujita, Hideto|Takamura, Hiroyuki|Ninomiya, Itasu|Kitagawa, Hirohisa|Fushida, Sachio|F
PMID: 22664794
Journal: J Hepatol. 2012 Oct;57(4):813-20.
Title: Role of the stromal-derived factor-1 (SDF-1)-CXCR4 axis in the interaction between hepatic stellate cells and cholangiocarcinoma.
Author: Gentilini, Alessandra|Rombouts, Krista|Galastri, Sara|Caligiuri, Alessandra|Mingarelli, Eleonora|Mello, Tommaso|Marra, Fabio|Mantero, Stefano|Roncalli, Massimo|Invernizzi, Pietro|Pinzani, Massimo
PMID: 22727731
Journal: Oncol Lett. 2013 Nov;6(5):1439-1446.
Title: CD24 induces the invasion of cholangiocarcinoma cells by upregulating CXCR4 and increasing the phosphorylation of ERK1/2.
Author: Leelawat, Kawin|Keeratichamroen, Siriporn|Leelawat, Surang|Tohtong, Rutaiwan
PMID: 24179538
Journal: Gut Liver. 2014 Mar;8(2):196-204.
Title: Silencing of CXCR4 inhibits tumor cell proliferation and neural invasion in human hilar cholangiocarcinoma.
Author: Tan, Xin-Yu|Chang, Shi|Liu, Wei|Tang, Hui-Huan
PMID: 24672662
Journal: J Exp Clin Cancer Res. 2014 Dec 4;33:103.
Title: Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway.
Author: Zhao, Shengqiang|Wang, Jing|Qin, Chengyong
PMID: 25471741
Journal: Oncotarget. 2015 Mar 10;6(7):5022-40.
Title: CXCR4 over-expression and survival in cancer: a system review and meta-analysis.
Author: Zhao, Hongli|Guo, Liyuan|Zhao, Hong|Zhao, Jiaxin|Weng, Hao|Zhao, Bin
PMID: 25669980
Journal: Mol Med Rep. 2015 Aug;12(2):2247-52.
Title: Cytotoxic effects of chemokine receptor 4 inhibition by AMD3100 in biliary tract cancer cells: Potential drug synergism with gemcitabine.
Author: Mayr, Christian|Neureiter, Daniel|Pichler, Martin|Berr, Frieder|Wagner, Andrej|Kiesslich, Tobias|Namberger, Konrad
PMID: 25846744
Journal: Mol Pharm. 2016 Mar 7;13(3):1073-80.
Title: Delivery of miR-200c Mimic with Poly(amido amine) CXCR4 Antagonists for Combined Inhibition of Cholangiocarcinoma Cell Invasiveness.
Author: Xie, Ying|Wehrkamp, Cody J|Li, Jing|Wang, Yan|Wang, Yazhe|Mott, Justin L|Oupicky, David
PMID: 26855082
Journal: J Cell Biochem. 2017 Nov;118(11):3643-3653.
Title: Long Non-Coding RNA MALAT1 Interacts With miR-204 to Modulate Human Hilar Cholangiocarcinoma Proliferation, Migration, and Invasion by Targeting CXCR4.
Author: Tan, Xinyu|Huang, Zhiguo|Li, Xiaogang
PMID: 28059437
Journal: Oncol Lett. 2017 Dec;14(6):7111-7120.
Title: Isolation and identification of tumor-initiating cell properties in human gallbladder cancer cell lines using the marker cluster of differentiation 133.
Author: Yu, Jiwei|Tang, Zhaohui|Gong, Wei|Zhang, Mingdi|Quan, Zhiwei
PMID: 29344142
Journal: J Surg Oncol. 2018 Sep 9.
Title: CD90 expression in human intrahepatic cholangiocarcinoma is associated with lymph node metastasis and poor prognosis.
Author: Yamaoka, Ryoya|Ishii, Takamichi|Kawai, Takayuki|Yasuchika, Kentaro|Miyauchi, Yuya|Kojima, Hidenobu|Katayama, Hokahiro|Ogiso, Satoshi|Fukumitsu, Ken|Uemoto, Shinji
PMID: 30196535