Primary Site >> Biliary tract Cancer

Gene >> CXCL12

Journal: Am J Pathol. 2006 Apr;168(4):1155-68.
Title: Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factor-alpha and stromal-derived factor-1 released in stroma.
Author: Ohira, Shusaku|Sasaki, Motoko|Harada, Kenichi|Sato, Yasunori|Zen, Yoh|Isse, Kumiko|Kozaka, Kazuto|Ishikawa, Akira|Oda, Koji|Nimura, Yuji|Nakanuma, Yasuni
PMID: 16565491
Journal: World J Gastroenterol. 2007 Mar 14;13(10):1561-8.
Title: Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
Author: Leelawat, Kawin|Leelawat, Surang|Narong, Siriluck|Hongeng, Suradej
PMID: 17461449
Journal: Clin Cancer Res. 2012 Jun 15;18(12):3270-80.
Title: Chemokine (C-X-C motif) ligand 12 is associated with gallbladder carcinoma progression and is a novel independent poor prognostic factor.
Author: Lee, Hyun Jung|Lee, Kyungmin|Lee, Dong Gwang|Bae, Kwang-Hee|Kim, Jang-Seong|Liang, Zhe Long|Huang, Song Mei|Suk Oh, Yoon|Kim, Ha Yon|Jo, Deog Yeon|Min, Jeong-Ki|Kim, Jin-Man|Lee, Hyo Jin
PMID: 22553346
Journal: Int J Oncol. 2012 Aug;41(2):573-82.
Title: Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma.
Author: Okamoto, Koichi|Tajima, Hidehiro|Nakanuma, Shinichi|Sakai, Seisho|Makino, Isamu|Kinoshita, Jun|Hayashi, Hironori|Nakamura, Keishi|Oyama, Katsunobu|Nakagawara, Hisatoshi|Fujita, Hideto|Takamura, Hiroyuki|Ninomiya, Itasu|Kitagawa, Hirohisa|Fushida, Sachio|F
PMID: 22664794
Journal: J Hepatol. 2012 Oct;57(4):813-20.
Title: Role of the stromal-derived factor-1 (SDF-1)-CXCR4 axis in the interaction between hepatic stellate cells and cholangiocarcinoma.
Author: Gentilini, Alessandra|Rombouts, Krista|Galastri, Sara|Caligiuri, Alessandra|Mingarelli, Eleonora|Mello, Tommaso|Marra, Fabio|Mantero, Stefano|Roncalli, Massimo|Invernizzi, Pietro|Pinzani, Massimo
PMID: 22727731
Journal: Gastroenterology. 2013 Nov;145(5):1121-32.
Title: Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma.
Author: Ene-Obong, Abasi|Clear, Andrew J|Watt, Jennifer|Wang, Jun|Fatah, Rewas|Riches, John C|Marshall, John F|Chin-Aleong, Joanne|Chelala, Claude|Gribben, John G|Ramsay, Alan G|Kocher, Hemant M
PMID: 23891972
Journal: Eur J Cancer. 2014 Dec;50(18):3125-35.
Title: Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme.
Author: Moehler, M|Maderer, A|Schimanski, C|Kanzler, S|Denzer, U|Kolligs, F T|Ebert, M P|Distelrath, A|Geissler, M|Trojan, J|Schutz, M|Berie, L|Sauvigny, C|Lammert, F|Lohse, A|Dollinger, M M|Lindig, U|Duerr, E M|Lubomierski, N|Zimmermann, S|Wachtlin, D|Kaiser, A-
PMID: 25446376
Journal: J Exp Clin Cancer Res. 2014 Dec 4;33:103.
Title: Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway.
Author: Zhao, Shengqiang|Wang, Jing|Qin, Chengyong
PMID: 25471741
Journal: Transl Oncol. 2018 Apr;11(2):353-357.
Title: The Correlation Between Serum Chemokines and Clinical Outcome in Patients with Advanced Biliary Tract Cancer.
Author: Lee, Su Jin|Kim, Jung Eun|Kim, Seung Tae|Lee, Jeeyun|Park, Se Hoon|Park, Joon Oh|Kang, Won Ki|Park, Young Suk|Lim, Ho Yeong
PMID: 29448202