Primary Site >> Pancreatic Cancer

Gene >> CSF2

Journal: J Biol Chem. 1979 Jul 25;254(14):6226-8.
Title: Purification of a colony-stimulating factor from cultured pancreatic carcinoma cells.
Author: Wu, M|Cini, J K|Yunis, A A
PMID: 312800
Journal: Blood Cells. 1980;6(4):679-88.
Title: Antibody to purified human colony-stimulating factor: use in the identification and isolation of granulocyte macrophage progenitor cells.
Author: Yunis, A A|Wu, M C|Miller, A M|Ingram, M|Files, N
PMID: 7008869
Journal: J Cell Physiol. 1982 Oct;113(1):67-72.
Title: Induced release and metabolism of arachidonic acid from myeloid cells by purified colony-stimulating factor.
Author: Ziboh, V A|Miller, A M|Wu, M C|Yunis, A A|Jimenez, J|Wong, G
PMID: 6813342
Journal: Exp Hematol. 1984 Dec;12(11):838-43.
Title: Further evidence supporting an in vivo role for colony-stimulating factor.
Author: Yunis, A A|Jimenez, J J|Wu, M C|Andreotti, P E
PMID: 6334613
Journal: Nervenarzt. 1985 Aug;56(8):410-6.
Title: [Metastases to the nervous system].
Author: Berlit, P|Ganshirt, H
PMID: 4058615
Journal: Eur J Haematol. 1987 Nov;39(5):462-6.
Title: Pancreatic carcinoma associated with marked eosinophilia: a case report.
Author: Hirata, J|Koga, T|Nishimura, J|Ibayashi, H
PMID: 3500871
Journal: Immunol Res. 1991;10(3-4):258-60.
Title: Proliferation of gastrointestinal carcinoma cells by T lymphocyte factors interleukin-3 and granulocyte-macrophage colony-stimulating factor.
Author: Dippold, W|Meyer zum Buschenfelde, K H
PMID: 1955751
Journal: Cancer. 1995 Oct 15;76(8):1356-62.
Title: Phase I/II trial of dexverapamil, epirubicin, and granulocyte-macrophage-colony stimulating factor in patients with advanced pancreatic adenocarcinoma.
Author: Kornek, G|Raderer, M|Schenk, T|Pidlich, J|Schulz, F|Globits, S|Tetzner, C|Scheithauer, W
PMID: 8620409
Journal: Adv Exp Med Biol. 1997;417:519-24.
Title: Immunotherapy of cancer. Generation of CEA specific CTL using CEA peptide pulsed dendritic cells.
Author: Alters, S E|Gadea, J R|Philip, R
PMID: 9286413
Journal: Hum Gene Ther. 1998 Sep 1;9(13):1951-71.
Title: A phase I clinical trial of lethally irradiated allogeneic pancreatic tumor cells transfected with the GM-CSF gene for the treatment of pancreatic adenocarcinoma.
Author: Jaffee, E M|Abrams, R|Cameron, J|Donehower, R|Duerr, M|Gossett, J|Greten, T F|Grochow, L|Hruban, R|Kern, S|Lillemoe, K D|O'Reilly, S|Pardoll, D|Pitt, H A|Sauter, P|Weber, C|Yeo, C
PMID: 9741433
Journal: Cancer J Sci Am. 1998 May-Jun;4(3):194-203.
Title: Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials.
Author: Jaffee, E M|Schutte, M|Gossett, J|Morsberger, L A|Adler, A J|Thomas, M|Greten, T F|Hruban, R H|Yeo, C J|Griffin, C A
PMID: 9612602
Journal: Anticancer Res. 1998 Jan-Feb;18(1A):165-70.
Title: Impaired in vivo tumor growth of human pancreatic carcinoma cells retrovirally transduced with GM-CSF gene.
Author: Kimura, M|Tagawa, M|Yoshida, Y|Takenouchi, T|Takenaga, K|Azuma, K|Yamaguchi, T|Saisho, H|Sakiyama, S
PMID: 9568072
Journal: Leukemia. 1999 Apr;13(4):585-9.
Title: Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation.
Author: Iida, M|Towatari, M|Nakao, A|Iida, H|Kiyoi, H|Nakano, Y|Tanimoto, M|Saito, H|Naoe, T
PMID: 10214865
Journal: Ann N Y Acad Sci. 1999;886:67-72.
Title: Immunotherapy of cancer.
Author: Jaffee, E M
PMID: 10667204
Journal: J Hepatobiliary Pancreat Surg. 2000;7(3):306-11.
Title: GM-CSF gene therapy using adenoviral vector in hamster pancreatic cancer.
Author: Ogawa, T|Kusumoto, M|Mizumoto, K|Sato, N|Nagai, E|Ikubo, A|Aoki, Y|Tanaka, M
PMID: 10982631
Journal: Cancer Immunol Immunother. 2000 Dec;49(10):544-50.
Title: Generation and functional characterisation of dendritic cells from patients with pancreatic carcinoma with special regard to clinical applicability.
Author: Piemonti, L|Monti, P|Zerbi, A|Balzano, G|Allavena, P|Di Carlo, V
PMID: 11129325
Journal: J Clin Oncol. 2001 Jan 1;19(1):145-56.
Title: Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activation.
Author: Jaffee, E M|Hruban, R H|Biedrzycki, B|Laheru, D|Schepers, K|Sauter, P R|Goemann, M|Coleman, J|Grochow, L|Donehower, R C|Lillemoe, K D|O'Reilly, S|Abrams, R A|Pardoll, D M|Cameron, J L|Yeo, C J
PMID: 11134207
Journal: Tissue Antigens. 2001 Jan;57(1):39-45.
Title: Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines.
Author: Seliger, B|Schreiber, K|Delp, K|Meissner, M|Hammers, S|Reichert, T|Pawlischko, K|Tampe, R|Huber, C
PMID: 11169257
Journal: Int J Cancer. 2001 May 1;92(3):441-50.
Title: Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma.
Author: Gjertsen, M K|Buanes, T|Rosseland, A R|Bakka, A|Gladhaug, I|Soreide, O|Eriksen, J A|Moller, M|Baksaas, I|Lothe, R A|Saeterdal, I|Gaudernack, G
PMID: 11291084
Journal: Clin Endocrinol (Oxf). 2001 Aug;55(2):271-7.
Title: Dendritic cell immunotherapy in a neuroendocrine pancreas carcinoma.
Author: Schott, M|Feldkamp, J|Lettmann, M|Simon, D|Scherbaum, W A|Seissler, J
PMID: 11531937
Journal: Cancer Lett. 2002 Oct 8;184(1):37-47.
Title: Antitumor effects induced by dendritic cell-based immunotherapy against established pancreatic cancer in hamsters.
Author: Akiyama, Yasuto|Maruyama, Kouji|Nara, Noriko|Hojo, Takashi|Cheng, Jin Yan|Mori, Toshio|Wiltrout, Robert H|Yamaguchi, Ken
PMID: 12104046
Journal: Cancer Gene Ther. 2002 Dec;9(12):967-78.
Title: Oncolytic herpes simplex virus vectors for cancer virotherapy.
Author: Varghese, Susan|Rabkin, Samuel D
PMID: 12522436
Journal: J Exp Med. 2004 Aug 2;200(3):297-306.
Title: Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients.
Author: Thomas, Amy Morck|Santarsiero, Lynn M|Lutz, Eric R|Armstrong, Todd D|Chen, Yi-Cheng|Huang, Lan-Qing|Laheru, Daniel A|Goggins, Michael|Hruban, Ralph H|Jaffee, Elizabeth M
PMID: 15289501
Journal: Cancer Immun. 2004 Aug 25;4:8.
Title: Prevention and reversal of tumor cell-induced monocyte deactivation by cytokines, purified protein derivative (PPD), and anti-IL-10 antibody.
Author: Baj-Krzyworzeka, Monika|Baran, Jaroslaw|Szatanek, Rafal|Stankiewicz, Danuta|Siedlar, Maciej|Zembala, Marek
PMID: 15327279
Journal: Cancer Gene Ther. 2005 Sep;12(9):725-36.
Title: The potential of oncolytic virus therapy for pancreatic cancer.
Author: Kasuya, Hideki|Takeda, Shin|Nomoto, Shuji|Nakao, Akimasa
PMID: 15818382
Journal: Clin Chem Lab Med. 2005;43(2):146-50.
Title: Hematopoietic cytokines in the sera of patients with pancreatic cancer.
Author: Mroczko, Barbara|Szmitkowski, Maciej|Wereszczynska-Siemiatkowska, Urszula|Jurkowska, Grazyna
PMID: 15843207
Journal: Br J Cancer. 2006 Dec 4;95(11):1474-82. Epub 2006 Oct 24.
Title: Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: A dose escalating phase I/II study.
Author: Bernhardt, S L|Gjertsen, M K|Trachsel, S|Moller, M|Eriksen, J A|Meo, M|Buanes, T|Gaudernack, G
PMID: 17060934
Journal: J Transl Med. 2007 Nov 26;5:60.
Title: Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer.
Author: Kaufman, Howard L|Kim-Schulze, Seunghee|Manson, Kelledy|DeRaffele, Gail|Mitcham, Josephine|Seo, Kang Seok|Kim, Dae Won|Marshall, John
PMID: 18039393
Journal: J Immunol. 2008 Nov 1;181(9):6595-603.
Title: Carcinoembryonic antigen-specific but not antiviral CD4+ T cell immunity is impaired in pancreatic carcinoma patients.
Author: Tassi, Elena|Gavazzi, Francesca|Albarello, Luca|Senyukov, Vladimir|Longhi, Renato|Dellabona, Paolo|Doglioni, Claudio|Braga, Marco|Di Carlo, Valerio|Protti, Maria Pia
PMID: 18941250
Journal: Anticancer Res. 2008 Jan-Feb;28(1B):379-87.
Title: Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes.
Author: Kondo, Hiroshi|Hazama, Shoichi|Kawaoka, Toru|Yoshino, Shigefumi|Yoshida, Shin|Tokuno, Kazuhisa|Takashima, Motonari|Ueno, Tomio|Hinoda, Yuji|Oka, Masaaki
PMID: 18383873
Journal: Clin Cancer Res. 2008 Mar 1;14(5):1455-63.
Title: Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation.
Author: Laheru, Dan|Lutz, Eric|Burke, James|Biedrzycki, Barbara|Solt, Sara|Onners, Beth|Tartakovsky, Irena|Nemunaitis, John|Le, Dung|Sugar, Elizabeth|Hege, Kristen|Jaffee, Elizabeth
PMID: 18316569
Journal: PLoS One. 2009 Oct 2;4(10):e7234.
Title: Non-redundant role for IL-12 and IL-27 in modulating Th2 polarization of carcinoembryonic antigen specific CD4 T cells from pancreatic cancer patients.
Author: Tassi, Elena|Braga, Marco|Longhi, Renato|Gavazzi, Francesca|Parmiani, Giorgio|Di Carlo, Valerio|Protti, Maria Pia
PMID: 19798410
Journal: Hepatobiliary Pancreat Dis Int. 2009 Oct;8(5):529-34.
Title: Effect of insulin on functional status of cord blood-derived dendritic cells and on dendritic cell-induced CTL cytotoxicity against pancreatic cancer cell lines.
Author: Liu, Qiu-Liang|Wang, Yi-Sheng|Wang, Jia-Xiang
PMID: 19822498
Journal: Expert Opin Investig Drugs. 2010 Feb;19(2):311-4.
Title: Combining low-dose cyclophosphamide with GM-CSF-secreting prostate cancer immunotherapy enhances antitumor immune effects.
Author: Antonarakis, Emmanuel S|Carducci, Michael A
PMID: 20047504
Journal: Cancer Immunol Immunother. 2010 Dec;59(12):1757-69.
Title: Identification and characterization of a tumor infiltrating CD56(+)/CD16 (-) NK cell subset with specificity for pancreatic and prostate cancer cell lines.
Author: Frankel, Timothy L|Burns, William|Riley, John|Morgan, Richard A|Davis, Jeremy L|Hanada, Kenichi|Quezado, Martha|Rosenberg, Steven A|Royal, Richard E
PMID: 20734041
Journal: J Cancer. 2010 Nov 3;1:209-22.
Title: The therapeutic value of monoclonal antibodies directed against immunogenic tumor glycoproteins.
Author: Arlen, Myron|Arlen, Philip|Tsang, Al|Wang, Xueping|Gupta, Rishab
PMID: 21060731
Journal: Ann Surg. 2011 Feb;253(2):328-35.
Title: A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation.
Author: Lutz, Eric|Yeo, Charles J|Lillemoe, Keith D|Biedrzycki, Barbara|Kobrin, Barry|Herman, Joseph|Sugar, Elizabeth|Piantadosi, Steven|Cameron, John L|Solt, Sara|Onners, Beth|Tartakovsky, Irena|Choi, Miri|Sharma, Rajni|Illei, Peter B|Hruban, Ralph H|Abrams, Ros
PMID: 21217520
Journal: Int J Biol Markers. 2012 Oct 8;27(3):e186-94.
Title: Role of the hematopoietic cytokines SCF, IL-3, GM-CSF and M-CSF in the diagnosis of pancreatic and ampullary cancer.
Author: Vasiliades, George|Kopanakis, Nikolaos|Vasiloglou, Michalis|Zografos, George|Margaris, Helias|Masselou, Kyriaki|Kokosi, Evniki|Liakakos, Theodore
PMID: 22865301
Journal: Nat Rev Gastroenterol Hepatol. 2012 Aug;9(8):426.
Title: Pancreatic cancer: The role of GM-CSF in pancreatic cancer unveiled.
Author: Greenhill, Claire
PMID: 22733349
Journal: Cancer Cell. 2012 Jun 12;21(6):836-47.
Title: Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia.
Author: Pylayeva-Gupta, Yuliya|Lee, Kyoung Eun|Hajdu, Cristina H|Miller, George|Bar-Sagi, Dafna
PMID: 22698407
Journal: Cancer Cell. 2012 Jun 12;21(6):715-6.
Title: Silencing the killers: paracrine immune suppression in pancreatic cancer.
Author: Cox, Adrienne D|Olive, Kenneth P
PMID: 22698396
Journal: Cancer Cell. 2012 Jun 12;21(6):822-35.
Title: Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.
Author: Bayne, Lauren J|Beatty, Gregory L|Jhala, Nirag|Clark, Carolyn E|Rhim, Andrew D|Stanger, Ben Z|Vonderheide, Robert H
PMID: 22698406
Journal: JOP. 2012 Mar 10;13(2):166-8.
Title: Novel agents in early phase clinical studies on refractory pancreatic cancer.
Author: Strimpakos, Alexios S|Syrigos, Kostas N|Saif, Muhammad Wasif
PMID: 22406592
Journal: Nucl Med Commun. 2013 Jan;34(1):64-70.
Title: Impact of cytokines on diffuse splenic 18F-fluorodeoxyglucose uptake during positron emission tomography/computed tomography.
Author: Pak, Kyoungjune|Kim, Seong-Jang|Kim, In Joo|Kim, Dong Uk|Kim, Keunyoung|Kim, Heeyoung
PMID: 23076270
Journal: J Control Release. 2013 May 10;167(3):238-47.
Title: Block/homo polyplex micelle-based GM-CSF gene therapy via intraperitoneal administration elicits antitumor immunity against peritoneal dissemination and exhibits safety potentials in mice and cynomolgus monkeys.
Author: Ohgidani, Masahiro|Furugaki, Koichi|Shinkai, Kentaro|Kunisawa, Yumi|Itaka, Keiji|Kataoka, Kazunori|Nakano, Kenji
PMID: 23422727
Journal: Curr Opin Immunol. 2013 Apr;25(2):200-5.
Title: Inflammatory networks and immune surveillance of pancreatic carcinoma.
Author: Vonderheide, Robert H|Bayne, Lauren J
PMID: 23422836
Journal: Cancer Res. 2013 May 15;73(10):3007-18.
Title: Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner.
Author: Mace, Thomas A|Ameen, Zeenath|Collins, Amy|Wojcik, Sylwia|Mair, Markus|Young, Gregory S|Fuchs, James R|Eubank, Tim D|Frankel, Wendy L|Bekaii-Saab, Tanios|Bloomston, Mark|Lesinski, Gregory B
PMID: 23514705
Journal: J Immunol. 2013 Aug 1;191(3):1486-95.
Title: Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells.
Author: Husain, Zaheed|Huang, Yannu|Seth, Pankaj|Sukhatme, Vikas P
PMID: 23817426
Journal: J Immunother. 2013 Sep;36(7):382-9.
Title: Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer.
Author: Le, Dung T|Lutz, Eric|Uram, Jennifer N|Sugar, Elizabeth A|Onners, Beth|Solt, Sara|Zheng, Lei|Diaz, Luis A Jr|Donehower, Ross C|Jaffee, Elizabeth M|Laheru, Daniel A
PMID: 23924790
Journal: World J Gastroenterol. 2013 Aug 21;19(31):5138-43.
Title: Preclinical evaluation of herpes simplex virus armed with granulocyte-macrophage colony-stimulating factor in pancreatic carcinoma.
Author: Liu, Hao|Yuan, Shou-Jun|Chen, Ying-Tai|Xie, Yi-Bin|Cui, Liang|Yang, Wei-Zhi|Yang, De-Xuan|Tian, Yan-Tao
PMID: 23964149
Journal: Ann Surg Oncol. 2013 Dec;20 Suppl 3:S725-30.
Title: Low total lymphocyte count is associated with poor survival in patients with resected pancreatic adenocarcinoma receiving a GM-CSF secreting pancreatic tumor vaccine.
Author: Schueneman, Aaron J|Sugar, Elizabeth A|Uram, Jennifer|Bigelow, Elaine|Herman, Joseph M|Edil, Barish H|Jaffee, Elizabeth M|Zheng, Lei|Laheru, Daniel A
PMID: 24046118
Journal: J Immunother Cancer. 2013 Jun 27;1:8.
Title: A randomized pilot phase I study of modified carcinoembryonic antigen (CEA) peptide (CAP1-6D)/montanide/GM-CSF-vaccine in patients with pancreatic adenocarcinoma.
Author: Geynisman, Daniel M|Zha, Yuanyuan|Kunnavakkam, Rangesh|Aklilu, Mebea|Catenacci, Daniel Vt|Polite, Blase N|Rosenbaum, Cara|Namakydoust, Azadeh|Karrison, Theodore|Gajewski, Thomas F|Kindler, Hedy L
PMID: 24829746
Journal: Cancer Immunol Immunother. 2014 Feb;63(2):175-83.
Title: The effects of gemcitabine and capecitabine combination chemotherapy and of low-dose adjuvant GM-CSF on the levels of myeloid-derived suppressor cells in patients with advanced pancreatic cancer.
Author: Annels, Nicola E|Shaw, Victoria E|Gabitass, Rachel F|Billingham, Lucinda|Corrie, Pippa|Eatock, Martin|Valle, Juan|Smith, David|Wadsley, Jonathan|Cunningham, David|Pandha, Hardev|Neoptolemos, John P|Middleton, Gary
PMID: 24292263
Journal: Cancer Lett. 2014 Nov 28;354(2):407-16.
Title: Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells.
Author: Peng, Meiyu|Huang, Bingqing|Zhang, Qi|Fu, Shuyu|Wang, Dan|Cheng, Xixi|Wu, Xi|Xue, Zhenyi|Zhang, Lijuan|Zhang, Da|Da, Yurong|Dai, Yun|Yang, Qing|Yao, Zhi|Qiao, Liang|Zhang, Rongxin
PMID: 25128650
Journal: J Transl Med. 2014 Jul 9;12:191.
Title: Ipilimumab augments antitumor activity of bispecific antibody-armed T cells.
Author: Yano, Hiroshi|Thakur, Archana|Tomaszewski, Elyse N|Choi, Minsig|Deol, Abhinav|Lum, Lawrence G
PMID: 25008236
Journal: Cancer Control. 2014 Jul;21(3):242-6.
Title: Novel pancreatic cancer vaccines could unleash the army within.
Author: Springett, Gregory M
PMID: 24955709
Journal: J Transl Med. 2014 Jun 19;12:175.
Title: Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer.
Author: Shindo, Yoshitaro|Hazama, Shoichi|Maeda, Yoshinari|Matsui, Hiroto|Iida, Michihisa|Suzuki, Nobuaki|Yoshimura, Kiyoshi|Ueno, Tomio|Yoshino, Shigefumi|Sakai, Kohei|Suehiro, Yutaka|Yamasaki, Takahiro|Hinoda, Yuji|Oka, Masaaki
PMID: 24947606
Journal: Cancer Immunol Res. 2014 Jul;2(7):616-31.
Title: Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation.
Author: Lutz, Eric R|Wu, Annie A|Bigelow, Elaine|Sharma, Rajni|Mo, Guanglan|Soares, Kevin|Solt, Sara|Dorman, Alvin|Wamwea, Anthony|Yager, Allison|Laheru, Daniel|Wolfgang, Christopher L|Wang, Jiang|Hruban, Ralph H|Anders, Robert A|Jaffee, Elizabeth M|Zheng, Lei
PMID: 24942756
Journal: Int J Oncol. 2014 Sep;45(3):1293-303.
Title: Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.
Author: Staff, Caroline|Mozaffari, Fariba|Frodin, Jan-Erik|Mellstedt, Hakan|Liljefors, Maria
PMID: 24919654
Journal: Oncotarget. 2015 Dec 15;6(40):43005-15.
Title: TGF-beta blockade depletes T regulatory cells from metastatic pancreatic tumors in a vaccine dependent manner.
Author: Soares, Kevin C|Rucki, Agnieszka A|Kim, Victoria|Foley, Kelly|Solt, Sara|Wolfgang, Christopher L|Jaffee, Elizabeth M|Zheng, Lei
PMID: 26515728
Journal: Cancer Res. 2015 Jul 1;75(13):2629-40.
Title: Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer.
Author: Takeuchi, Shintaro|Baghdadi, Muhammad|Tsuchikawa, Takahiro|Wada, Haruka|Nakamura, Toru|Abe, Hirotake|Nakanishi, Sayaka|Usui, Yuu|Higuchi, Kohtaro|Takahashi, Mizuna|Inoko, Kazuho|Sato, Syoki|Takano, Hironobu|Shichinohe, Toshiaki|Seino, Ken-ichiro|Hirano, S
PMID: 25952647
Journal: PLoS One. 2015 May 6;10(5):e0125273.
Title: Association between Variants in Atopy-Related Immunologic Candidate Genes and Pancreatic Cancer Risk.
Author: Cotterchio, Michelle|Lowcock, Elizabeth|Bider-Canfield, Zoe|Lemire, Mathieu|Greenwood, Celia|Gallinger, Steven|Hudson, Thomas
PMID: 25945796
Journal: Int J Cancer. 2015 Jan 1;136(1):127-37.
Title: Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival.
Author: De Remigis, Alessandra|de Gruijl, Tanja D|Uram, Jennifer N|Tzou, Schey-Cherng|Iwama, Shintaro|Talor, Monica V|Armstrong, Todd D|Santegoets, Saskia J A M|Slovin, Susan F|Zheng, Lei|Laheru, Daniel A|Jaffee, Elizabeth M|Gerritsen, Winald R|van den Eertwegh,
PMID: 24832153
Journal: Int J Cancer. 2015 Mar 1;136(5):1065-72.
Title: GMCSF-armed vaccinia virus induces an antitumor immune response.
Author: Parviainen, Suvi|Ahonen, Marko|Diaconu, Iulia|Kipar, Anja|Siurala, Mikko|Vaha-Koskela, Markus|Kanerva, Anna|Cerullo, Vincenzo|Hemminki, Akseli
PMID: 25042001
Journal: Clin Transl Immunology. 2016 Dec 23;5(12):e119.
Title: GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro.
Author: Gargett, Tessa|Christo, Susan N|Hercus, Timothy R|Abbas, Nazim|Singhal, Nimit|Lopez, Angel F|Brown, Michael P
PMID: 28090321
Journal: Cancer Discov. 2016 Aug;6(8):886-99.
Title: GM-CSF Mediates Mesenchymal-Epithelial Cross-talk in Pancreatic Cancer.
Author: Waghray, Meghna|Yalamanchili, Malica|Dziubinski, Michele|Zeinali, Mina|Erkkinen, Marguerite|Yang, Huibin|Schradle, Kara A|Urs, Sumithra|Pasca Di Magliano, Marina|Welling, Theodore H|Palmbos, Phillip L|Abel, Ethan V|Sahai, Vaibhav|Nagrath, Sunitha|Wang, Li
PMID: 27184426
Journal: Br J Cancer. 2016 Mar 1;114(5):510-8.
Title: Immunobiological effects of gemcitabine and capecitabine combination chemotherapy in advanced pancreatic ductal adenocarcinoma.
Author: Middleton, Gary|Greenhalf, William|Costello, Eithne|Shaw, Victoria|Cox, Trevor|Ghaneh, Paula|Palmer, Daniel H|Neoptolemos, John P
PMID: 26931369
Journal: Cancer Immunol Res. 2016 Mar;4(3):225-33.
Title: Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer.
Author: Jhaveri, Darshil T|Kim, Min-Sik|Thompson, Elizabeth D|Huang, Lanqing|Sharma, Rajni|Klein, Alison P|Zheng, Lei|Le, Dung T|Laheru, Daniel A|Pandey, Akhilesh|Jaffee, Elizabeth M|Anders, Robert A
PMID: 26842750
Journal: Hepatobiliary Pancreat Dis Int. 2016 Feb;15(1):99-105.
Title: Circulating myeloid-derived suppressor cells in patients with pancreatic cancer.
Author: Xu, Xiao-Dong|Hu, Jun|Wang, Min|Peng, Feng|Tian, Rui|Guo, Xing-Jun|Xie, Yu|Qin, Ren-Yi
PMID: 26818550
Journal: J Cancer. 2016 Jan 1;7(1):42-9.
Title: Increasing the Inflammatory Competence of Macrophages with IL-6 or with Combination of IL-4 and LPS Restrains the Invasiveness of Pancreatic Cancer Cells.
Author: Salmiheimo, Aino N E|Mustonen, Harri K|Vainionpaa, Sanna A A|Shen, Zhanlong|Kemppainen, Esko A J|Seppanen, Hanna E|Puolakkainen, Pauli A
PMID: 26722359
Journal: Clin Cancer Res. 2016 Mar 1;22(5):1048-54.
Title: Molecular Pathways: Mechanism of Action for Talimogene Laherparepvec, a New Oncolytic Virus Immunotherapy.
Author: Kohlhapp, Frederick J|Kaufman, Howard L
PMID: 26719429
Journal: Proteomics. 2016 Feb;16(3):516-31.
Title: Surveying the serologic proteome in a tissue-specific kras(G12D) knockin mouse model of pancreatic cancer.
Author: Ludwig, Michael R|Kojima, Kyoko|Bowersock, Gregory J|Chen, Dongquan|Jhala, Nirag C|Buchsbaum, Donald J|Grizzle, William E|Klug, Christopher A|Mobley, James A
PMID: 26572242
Journal: Immunotherapy. 2016 Feb;8(2):223-34.
Title: Primary analysis for clinical efficacy of immunotherapy in patients with pancreatic cancer.
Author: Chen, Linghua|Zhang, Xiaoyan
PMID: 26565954
Journal: Oncotarget. 2017 Feb 14;8(7):10785-10808.
Title: Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens.
Author: Pathangey, Latha B|McCurry, Dustin B|Gendler, Sandra J|Dominguez, Ana L|Gorman, Jessica E|Pathangey, Girish|Mihalik, Laurie A|Dang, Yushe|Disis, Mary L|Cohen, Peter A
PMID: 27974697
Journal: Anticancer Res. 2017 Jan;37(1):223-228.
Title: Granulocyte Colony-stimulating Factor Producing Anaplastic Carcinoma of the Pancreas: Case Report and Review of the Literature.
Author: Vinzens, Sarah|Zindel, Joel|Zweifel, Martin|Rau, Tilman|Gloor, Beat|Wochner, Annette
PMID: 28011495
Journal: Cancer Lett. 2017 May 28;394:76-87.
Title: Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer.
Author: Leal, Ana S|Williams, Charlotte R|Royce, Darlene B|Pioli, Patricia A|Sporn, Michael B|Liby, Karen T
PMID: 28254412
Journal: Cancer Biol Ther. 2017 Mar 4;18(3):137-141.
Title: Abscopal effect of metastatic pancreatic cancer after local radiotherapy and granulocyte-macrophage colony-stimulating factor therapy.
Author: Shi, Fang|Wang, Xin|Teng, Feifei|Kong, Li|Yu, Jinming
PMID: 28267380
Journal: J Hematol Oncol. 2017 Mar 28;10(1):76.
Title: The role of stromal cancer-associated fibroblasts in pancreatic cancer.
Author: von Ahrens, Dagny|Bhagat, Tushar D|Nagrath, Deepak|Maitra, Anirban|Verma, Amit
PMID: 28351381
Journal: Oncotarget. 2016 Jul 20;8(33):54054-54067.
Title: The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma.
Author: Han, Song|Gonzalo, David H|Feely, Michael|Delitto, Daniel|Behrns, Kevin E|Beveridge, Mark|Zhang, DongYu|Thomas, Ryan|Trevino, Jose G|Schmittgen, Thomas D|Hughes, Steven J
PMID: 28903323
Journal: Oncotarget. 2017 Sep 22;8(59):99693-99706.
Title: Apolipoprotein A-I mimetic peptide 4F suppresses tumor-associated macrophages and pancreatic cancer progression.
Author: Peng, Meiyu|Zhang, Qi|Cheng, Yingnan|Fu, Shuyu|Yang, Huipeng|Guo, Xiangdong|Zhang, Jieyou|Wang, Lina|Zhang, Lijuan|Xue, Zhenyi|Li, Yan|Da, Yurong|Yao, Zhi|Qiao, Liang|Zhang, Rongxin
PMID: 29245934
Journal: J Cachexia Sarcopenia Muscle. 2018 Apr;9(2):358-368.
Title: Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naive pancreatic cancer patients.
Author: Talbert, Erin E|Lewis, Heather L|Farren, Matthew R|Ramsey, Mitchell L|Chakedis, Jeffery M|Rajasekera, Priyani|Haverick, Ericka|Sarna, Angela|Bloomston, Mark|Pawlik, Timothy M|Zimmers, Teresa A|Lesinski, Gregory B|Hart, Phil A|Dillhoff, Mary E|Schmidt, Car
PMID: 29316343
Journal: Cancer Res. 2018 Sep 19. pii: 0008-5472.CAN-18-0579.
Title: Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer.
Author: Srinivasan, Supriya|Totiger, Tulasigeri|Shi, Chanjuan|Castellanos, Jason|Lamichhane, Purushottam|Dosch, Austin R|Messaggio, Fanuel|Kashikar, Nilesh|Honnenahally, Kumaraswamy|Ban, Yuguang|Merchant, Nipun B|VanSaun, Michael N|Nagathihalli, Nagaraj S
PMID: 30232221