Primary Site >> Colorectal Cancer

Gene >> CIP2A

Journal: Cell. 2007 Jul 13;130(1):51-62.
Title: CIP2A inhibits PP2A in human malignancies.
Author: Junttila, Melissa R|Puustinen, Pietri|Niemela, Minna|Ahola, Raija|Arnold, Hugh|Bottzauw, Trine|Ala-aho, Risto|Nielsen, Christina|Ivaska, Johanna|Taya, Yoichi|Lu, Shi-Long|Lin, Shujun|Chan, Edward K L|Wang, Xiao-Jing|Grenman, Reidar|Kast, Juergen|Kallunki,
PMID: 17632056
Journal: Cancer Biol Ther. 2012 Mar;13(5):289-95.
Title: CIP2A overexpression is associated with c-Myc expression in colorectal cancer.
Author: Bockelman, Camilla|Koskensalo, Selja|Hagstrom, Jaana|Lundin, Mikael|Ristimaki, Ari|Haglund, Caj
PMID: 22310977
Journal: J Gastrointest Surg. 2012 May;16(5):1037-47.
Title: CIP2A is a predictor of poor prognosis in colon cancer.
Author: Teng, Hao-Wei|Yang, Shung-Haur|Lin, Jen-Kou|Chen, Wei-Shone|Lin, Tzu-Chen|Jiang, Jeng-Kai|Yen, Chueh-Chuan|Li, Anna Fen-Yau|Chen, Paul Chih-Hsueh|Lan, Yuan-Tzu|Lin, Chun-Chi|Hsu, Yen-Ning|Wang, Hsei-Wei|Chen, Kuen-Feng
PMID: 22328001
Journal: PLoS One. 2013 Oct 1;8(10):e75292.
Title: CIP2A influences survival in colon cancer and is critical for maintaining Myc expression.
Author: Wiegering, Armin|Pfann, Christina|Uthe, Friedrich Wilhelm|Otto, Christoph|Rycak, Lukas|Mader, Uwe|Gasser, Martin|Waaga-Gasser, Anna-Maria|Eilers, Martin|Germer, Christoph-Thomas
PMID: 24098375
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Nov;16(11):1102-6.
Title: [Expression of cancerous inhibitor of protein phosphatase 2A in tissue microarray of colorectal cancer and its clinical significance].
Author: Peng, Xing-yu|Chen, Wei|Zhou, Kai|Fu, Jian-ping|Fu, Ping|Zeng, Qing-li
PMID: 24277410
Journal: Mol Cancer Ther. 2014 Apr;13(4):938-47.
Title: PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential.
Author: Cristobal, Ion|Manso, Rebeca|Rincon, Raul|Carames, Cristina|Senin, Clara|Borrero, Aurea|Martinez-Useros, Javier|Rodriguez, Maria|Zazo, Sandra|Aguilera, Oscar|Madoz-Gurpide, Juan|Rojo, Federico|Garcia-Foncillas, Jesus
PMID: 24448818
Journal: J Cancer Res Clin Oncol. 2014 Apr;140(4):561-71.
Title: Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism.
Author: Wang, Hsei-Wei|Yang, Shung-Haur|Huang, Guan-Da|Lin, Jen-Kou|Chen, Wei-Shone|Jiang, Jeng-Kai|Lan, Yuan-Tzu|Lin, Chun-Chi|Hwang, Wei-Lun|Tzeng, Cheng-Hwai|Li, Anna Fen-Yau|Yen, Chueh-Chuan|Teng, Hao-Wei
PMID: 24493623
Journal: Mol Med Rep. 2014 Jul;10(1):387-92.
Title: Role of CIP2A in the antitumor effect of bortezomib in colon cancer.
Author: Ding, Yayun|Wang, Yueguo|Ju, Shaoqing|Wu, Xinghua|Zhu, Wencai|Shi, Feng|Mao, Liping
PMID: 24789441
Journal: Oncotarget. 2014 Jul 15;5(13):4581-602.
Title: Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands.
Author: De, Pradip|Carlson, Jennifer|Leyland-Jones, Brian|Dey, Nandini
PMID: 25015035
Journal: BMC Cancer. 2015 Apr 17;15:301.
Title: Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomy.
Author: Chen, Kuen-Feng|Yen, Chueh-Chuan|Lin, Jen-Kou|Chen, Wei-Shone|Yang, Shung-Haur|Jiang, Jeng-Kai|Lan, Yuan-Tzu|Lin, Chun-Chi|Yu, Hui-Chuan|Hsu, Hui-Mei|Lin, Wen-Ling|Teng, Hao-Wei
PMID: 25896895
Journal: Oncol Rep. 2016 May;35(5):2833-42.
Title: FTY720-induced enhancement of autophagy protects cells from FTY720 cytotoxicity in colorectal cancer.
Author: Li, Juan|Wang, Shu-Wei|Zhang, Dong-Sheng|Sun, Ye|Zhu, Chun-Yan|Fei, Qiang|Hu, Jun|Zhang, Chuan|Sun, Yue-Ming
PMID: 26985637
Journal: Oncotarget. 2016 May 3;7(18):25862-71.
Title: HDAC1 controls CIP2A transcription in human colorectal cancer cells.
Author: Balliu, Manjola|Cellai, Cristina|Lulli, Matteo|Laurenzana, Anna|Torre, Eugenio|Vannucchi, Alessandro Maria|Paoletti, Francesco
PMID: 27029072
Journal: J Biol Chem. 2017 May 19;292(20):8331-8341.
Title: The DEAD-box RNA helicase DDX41 is a novel repressor of p21(WAF1/CIP1) mRNA translation.
Author: Peters, Dominik|Radine, Claudia|Reese, Alina|Budach, Wilfried|Sohn, Dennis|Janicke, Reiner U
PMID: 28348086
Journal: Cancer Med. 2018 Mar;7(3):698-706.
Title: Protein phosphatase 2A (PP2A) inhibitor CIP2A indicates resistance to radiotherapy in rectal cancer.
Author: Birkman, Eva-Maria|Elzagheid, Adam|Jokilehto, Terhi|Avoranta, Tuulia|Korkeila, Eija|Kulmala, Jarmo|Syrjanen, Kari|Westermarck, Jukka|Sundstrom, Jari
PMID: 29441695
Journal: Int J Oncol. 2018 Mar 16.
Title: Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting CIP2A.
Author: Jin, Lan|Si, Yuan|Hong, Xing|Liu, Pengfei|Zhu, Beibei|Yu, Huiliang|Zhao, Xinhua|Qin, Shanshan|Xiong, Mengyuan|Liu, Ying|Luo, Zhiguo|Guo, Yang
PMID: 29568959
Journal: Int J Clin Oncol. 2018 Oct;23(5):917-923.
Title: Multi-panel assay of serum autoantibodies in colorectal cancer.
Author: Ushigome, Mitsunori|Nabeya, Yoshihiro|Soda, Hiroaki|Takiguchi, Nobuhiro|Kuwajima, Akiko|Tagawa, Masatoshi|Matsushita, Kazuyuki|Koike, Junichi|Funahashi, Kimihiko|Shimada, Hideaki
PMID: 29691673
Journal: PLoS One. 2018 Jul 25;13(7):e0199675.
Title: Prognostic significance of CIP2A expression in solid tumors: A meta-analysis.
Author: Tang, Min|Shen, Jiao-Feng|Li, Ping|Zhou, Li-Na|Zeng, Ping|Cui, Xi-Xi|Chen, Min-Bin|Tian, Ye
PMID: 30044786
Journal: Mol Oncol. 2018 Oct;12(10):1706-1717.
Title: ER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer.
Author: Liu, Chun-Yu|Hsu, Chia-Chi|Huang, Tzu-Ting|Lee, Chia-Han|Chen, Ji-Lin|Yang, Shung-Haur|Jiang, Jeng-Kai|Chen, Wei-Shone|Lee, Kuan-Der|Teng, Hao-Wei
PMID: 30063110
Journal: Life Sci. 2018 Sep 15;209:498-506.
Title: Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway.
Author: Wang, Ning|Zhou, Fang|Guo, Jinhui|Zhu, Huaiyuan|Luo, Shanshui|Cao, Jingjing
PMID: 30144452