Primary Site >> Pancreatic Cancer

Gene >> CFTR

Journal: Am J Physiol. 1992 Jul;263(1 Pt 1):C176-86.
Title: Altered sulfate transport via anion exchange in CFPAC is corrected by retrovirus-mediated CFTR gene transfer.
Author: Elgavish, A|Meezan, E
PMID: 1378996
Journal:
Title: Pancreatitis Overview
Author: LaRusch, Jessica|Solomon, Sheila|Whitcomb, David C
PMID: 24624459
Journal: Eur J Cell Biol. 1994 Oct;65(1):214-9.
Title: Abnormal subcellular localization of mutated CFTR protein in a cystic fibrosis epithelial cell line.
Author: Demolombe, S|Baro, I|Laurent, M|Hongre, A S|Pavirani, A|Escande, D
PMID: 7534234
Journal: Pflugers Arch. 2000;439(3 Suppl):R50-2.
Title: Evidence that hereditary pancreatitis is genetically heterogeneous disorder.
Author: Ravnik-Glavac, M|Dean, M|di Sant'Agnese, P|Chernick, M|Kozelj, M|Krizman, I|Glavac, D
PMID: 10653140
Journal: Pflugers Arch. 2000 Jan;439(Suppl 1):r050-r052.
Title: Evidence that hereditary pancreatitis is genetically heterogeneous disorder.
Author: Ravnik-Glavac, Metka|Dean, Michael|Sant'Agnese, Paul di|Chernick, Mila|Kozelj, Matjaz|Krizman, Igor|Glavac, Damjan
PMID: 28176071
Journal: Gut. 2001 Jan;48(1):70-4.
Title: Cystic fibrosis transmembrane regulator (CFTR) DeltaF508 mutation and 5T allele in patients with chronic pancreatitis and exocrine pancreatic cancer. PANKRAS II Study Group.
Author: Malats, N|Casals, T|Porta, M|Guarner, L|Estivill, X|Real, F X
PMID: 11115825
Journal: Pancreatology. 2001;1(5):472-6.
Title: Gene-environment interactions in pancreatic cancer.
Author: Malats, N
PMID: 12120227
Journal: Pancreas. 2003 Nov;27(4):332-6.
Title: Mutations of the CFTR gene in pancreatic disease.
Author: Pezzilli, Raffaele|Morselli-Labate, Antonio Maria|Mantovani, Vilma|Romboli, Elisabetta|Selva, Paola|Migliori, Marina|Corinaldesi, Roberto|Gullo, Lucio
PMID: 14576497
Journal: Cancer Biol Ther. 2003 Nov-Dec;2(6):652-5.
Title: Polymorphisms of SPINK1 N34S and CFTR in patients with sporadic and familial pancreatic cancer.
Author: Matsubayashi, Hiroyuki|Fukushima, Noriyoshi|Sato, Norihiro|Brune, Kieran|Canto, Marcia|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E|Goggins, Michael
PMID: 14688470
Journal: Dig Dis. 2003;21(4):346-50.
Title: Identification of patients with genetic risk factors of pancreatitis: impact on treatment and cancer prevention.
Author: Keim, Volker
PMID: 14752225
Journal: Med Sci Monit. 2004 Dec;10(12):RA325-8.
Title: Genetic aspects of chronic pancreatitis.
Author: Teich, Niels|Mossner, Joachim
PMID: 15567996
Journal: Nihon Rinsho. 2004 Nov;62(11):2122-7.
Title: [Pancreatitis-associated gene mutations].
Author: Nishimori, Isao|Onishi, Saburo
PMID: 15552898
Journal: Korean J Gastroenterol. 2005 Feb;45(2):143-7.
Title: [Hereditary pancreatitis].
Author: Kim, Yong-Tae
PMID: 15725720
Journal: Praxis (Bern 1994). 2005 May 18;94(20):811-7.
Title: [Chronic pancreatitis--pancreas cancer: influence of genetic factors].
Author: Keim, V
PMID: 15957615
Journal: Scand J Surg. 2005;94(2):103-7.
Title: Genetics of pancreatitis.
Author: Keim, V
PMID: 16111090
Journal: World J Gastroenterol. 2006 Oct 21;12(39):6343-8.
Title: Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients.
Author: Piepoli, Ada|Gentile, Annamaria|Valvano, Maria Rosa|Barana, Daniela|Oliani, Cristina|Cotugno, Rosa|Quitadamo, Michele|Andriulli, Angelo|Perri, Francesco
PMID: 17072959
Journal: Pancreas. 2006 Nov;33(4):364-70.
Title: Cigarette smoke-induced differential expression of the genes involved in exocrine function of the rat pancreas.
Author: Wittel, Uwe A|Singh, Ajay P|Henley, Brandon J|Andrianifahanana, Mahefatiana|Akhter, Mohammed P|Cullen, Diane M|Batra, Surinder K
PMID: 17079941
Journal: Praxis (Bern 1994). 2006 Oct 18;95(42):1623-6.
Title: [Hereditary pancreatitis].
Author: Simon, P|Weiss, F U|Mayerle, J|Kraft, M|Lerch, M M
PMID: 17111846
Journal: Oncogene. 2007 Jan 4;26(1):30-41. Epub 2006 Jun 26.
Title: MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms.
Author: Singh, A P|Chauhan, S C|Andrianifahanana, M|Moniaux, N|Meza, J L|Copin, M C|van Seuningen, I|Hollingsworth, M A|Aubert, J P|Batra, S K
PMID: 16799633
Journal: Orphanet J Rare Dis. 2007 Jan 4;2:1.
Title: Hereditary chronic pancreatitis.
Author: Rosendahl, Jonas|Bodeker, Hans|Mossner, Joachim|Teich, Niels
PMID: 17204147
Journal: J Pediatr Surg. 2009 Nov;44(11):2078-82.
Title: Hereditary pancreatitis in children: surgical implications with special regard to genetic background.
Author: Schmitt, Francoise|Le Henaff, Gaelle|Piloquet, Hugues|Leclair, Marc D|David, Albert|Heloury, Yves|Podevin, Guillaume
PMID: 19944211
Journal: Cancer. 2010 Jan 1;116(1):203-9.
Title: Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations and risk for pancreatic adenocarcinoma.
Author: McWilliams, Robert R|Petersen, Gloria M|Rabe, Kari G|Holtegaard, Leonard M|Lynch, Pamela J|Bishop, Michele D|Highsmith, W Edward Jr
PMID: 19885835
Journal: Am J Gastroenterol. 2010 Aug;105(8):1876-83.
Title: Genetic, epidemiological, and clinical aspects of hereditary pancreatitis: a population-based cohort study in Denmark.
Author: Joergensen, Maiken Thyregod|Brusgaard, Klaus|Cruger, Dorthe Gylling|Gerdes, Anne-Marie|Schaffalitzky de Muckadell, Ove B
PMID: 20502448
Journal: Gut. 2010 Mar;59(3):357-63.
Title: The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families.
Author: Grocock, Christopher J|Rebours, Vinciane|Delhaye, Myriam N|Andren-Sandberg, Ake|Weiss, Frank Ulrich|Mountford, Roger|Harcus, Matthew J|Niemczyck, Edyta|Vitone, Louis J|Dodd, Susanna|Jorgensen, Maiken Thyregod|Ammann, Rudolf W|Schaffalitzky de Muckadell, O
PMID: 19951905
Journal: Pancreas. 2011 Nov;40(8):1188-94.
Title: ABO blood group and chronic pancreatitis risk in the NAPS2 cohort.
Author: Greer, Julia B|LaRusch, Jessica|Brand, Randall E|O'Connell, Michael R|Yadav, Dhiraj|Whitcomb, David C
PMID: 21792085
Journal: Vnitr Lek. 2011 Nov;57(11):891-6.
Title: [Chronic pancreatitis in 2011].
Author: Dite, P|Trna, J|Novotny, I|Floreanova, K|Nechutova, H|Geryk, E
PMID: 22165691
Journal: Acta Chir Iugosl. 2011;58(3):43-7.
Title: [CFTR F508DEL mutation and 5T allele in patients with chronic pancreatitis and pancreatic adenocarcinoma].
Author: Nikolic, Aleksandra|Dinic, Jelena|Radojkovic, Dragica|Lukic, Snezana|Popovic, Dragan|Ugljesic, Milenko|Knezevic, Srboljub
PMID: 22369017
Journal: Mol Med Rep. 2012 Feb;5(2):449-51.
Title: PRSS1 intron mutations in patients with pancreatic cancer and chronic pancreatitis.
Author: Gao, Feng|Liu, Qi-Cai|Zhang, Sheng|Zhuang, Ze-Hao|Lin, Cai-Zhu|Lin, Xin-Hua
PMID: 22109105
Journal: Internist (Berl). 2012 Apr;53(4):384, 386-8, 390-1.
Title: [Genetically determined pancreatic diseases].
Author: Rosendahl, J|Mossner, J
PMID: 22410943
Journal: Digestion. 2013;87(4):229-39.
Title: Clinical and morphological characteristics of sporadic genetically determined pancreatitis as compared to idiopathic pancreatitis: higher risk of pancreatic cancer in CFTR variants.
Author: Hamoir, Coralie|Pepermans, Xavier|Piessevaux, Hubert|Jouret-Mourin, Anne|Weynand, Birgit|Habyalimana, Jean-Baptiste|Leal, Teresinha|Geubel, Andre|Gigot, Jean-Francois|Deprez, Pierre H
PMID: 23751316
Journal: Evid Based Complement Alternat Med. 2013;2013:471739.
Title: In Vitro Global Gene Expression Analyses Support the Ethnopharmacological Use of Achyranthes aspera.
Author: Subbarayan, Pochi R|Sarkar, Malancha|Nathanson, Lubov|Doshi, Nikesh|Lokeshwar, Balakrishna L|Ardalan, Bach
PMID: 24454496
Journal: World J Gastroenterol. 2013 Jun 7;19(21):3332-8.
Title: PRSS1_p.Leu81Met mutation results in autoimmune pancreatitis.
Author: Gao, Feng|Li, Yue-Ming|Hong, Guo-Lin|Xu, Zhi-Feng|Liu, Qi-Cai|He, Qing-Liang|Lin, Li-Qing|Weng, Shao-Huang
PMID: 23745036
Journal: Mol Genet Metab. 2013 Jul;109(3):296-300.
Title: Characterization of two deletions of the CTRC locus.
Author: Masson, Emmanuelle|Hammel, Pascal|Garceau, Cecile|Benech, Caroline|Quemener-Redon, Sylvia|Chen, Jian-Min|Ferec, Claude
PMID: 23721890
Journal: Therap Adv Gastroenterol. 2013 Mar;6(2):169-79.
Title: Hereditary pancreatitis for the endoscopist.
Author: Patel, Milan R|Eppolito, Amanda L|Willingham, Field F
PMID: 23503650
Journal: Pancreas. 2014 Oct;43(7):1078-82.
Title: CFTR, SPINK1, PRSS1, and CTRC mutations are not associated with pancreatic cancer in German patients.
Author: Schubert, Stephanie|Traub, Frank|Brakensiek, Kai|von Kopylow, Kathrein|Marohn, Britta|Maelzer, Madeleine|Gaedcke, Jochen|Kreipe, Hans|Stuhrmann, Manfred
PMID: 25003218
Journal: Cent Eur J Immunol. 2014;39(1):77-82.
Title: Multiple gene mutations in patients with type 2 autoimmune pancreatitis and its clinical features.
Author: Dong, Feng|Chen, Qing-Quan|Zhuang, Ze-Hao|He, Qing-Liang|Wang, Feng-Qing|Liu, Qi-Cai|Liu, He-Kun|Wang, Yu
PMID: 26155104
Journal: World J Gastrointest Oncol. 2016 Mar 15;8(3):282-8.
Title: Emerging role of cystic fibrosis transmembrane conductance regulator - an epithelial chloride channel in gastrointestinal cancers.
Author: Hou, Yuning|Guan, Xiaoqing|Yang, Zhe|Li, Chunying
PMID: 26989463
Journal: Tumour Biol. 2017 May;39(5):1010428317699800.
Title: ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer.
Author: Dvorak, Pavel|Pesta, Martin|Soucek, Pavel
PMID: 28468577
Journal: Pol Przegl Chir. 2017 Oct 31;89(5):48-53.
Title: CTRC gene polymorphism may increase pancreatic cancer risk - preliminary study.
Author: Gluszek, Stanislaw|Kowalik, Artur|Koziel, Dorota|Wawrzycka, Iwona|Gluszek-Osuch, Martyna|Matykiewicz, Jaroslaw
PMID: 29154238
Journal: Biochem Biophys Res Commun. 2018 Apr 30;499(1):37-43.
Title: Detection and proteomic characterization of extracellular vesicles in human pancreatic juice.
Author: Osteikoetxea, Xabier|Benke, Marton|Rodriguez, Marta|Paloczi, Krisztina|Sodar, Barbara W|Szvicsek, Zsuzsanna|Szabo-Taylor, Katalin|Vukman, Krisztina V|Kittel, Agnes|Wiener, Zoltan|Vekey, Karoly|Harsanyi, Laszlo|Szucs, Akos|Turiak, Lilla|Buzas, Edit I
PMID: 29550476
Journal: Pancreas. 2018 Sep;47(8):924-936.
Title: Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts.
Author: Zhan, Wei|Shelton, Celeste A|Greer, Phil J|Brand, Randall E|Whitcomb, David C
PMID: 30113427
Journal: Pancreas. 2018 Oct;47(9):1078-1086.
Title: Pancreatitis-Associated Genes and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis.
Author: Cazacu, Irina Mihaela|Farkas, Nelli|Garami, Andras|Balasko, Marta|Mosdosi, Bernadett|Alizadeh, Hussain|Gyongyi, Zoltan|Rakonczay, Zoltan Jr|Vigh, Eva|Habon, Tamas|Czopf, Laszlo|Lazarescu, Marilena Alina|Eross, Balint|Sahin-Toth, Miklos|Hegyi, Peter
PMID: 30134356