Primary Site >> Colorectal Cancer

Gene >> CERS6

Journal: Oncogene. 2009 Feb 26;28(8):1132-41.
Title: Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.
Author: White-Gilbertson, S|Mullen, T|Senkal, C|Lu, P|Ogretmen, B|Obeid, L|Voelkel-Johnson, C
PMID: 19137010
Journal: Mol Pharmacol. 2009 Aug;76(2):342-55.
Title: Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
Author: Walker, Teneille|Mitchell, Clint|Park, Margaret A|Yacoub, Adly|Graf, Martin|Rahmani, Mohamed|Houghton, Peter J|Voelkel-Johnson, Christina|Grant, Steven|Dent, Paul
PMID: 19483104
Journal: Biochem Pharmacol. 2010 Dec 1;80(11):1632-40.
Title: Activation of ceramide synthase 6 by celecoxib leads to a selective induction of C16:0-ceramide.
Author: Schiffmann, Susanne|Ziebell, Simone|Sandner, Jessica|Birod, Kerstin|Deckmann, Klaus|Hartmann, Daniela|Rode, Sina|Schmidt, Helmut|Angioni, Carlo|Geisslinger, Gerd|Grosch, Sabine
PMID: 20735991
Journal: J Biol Chem. 2015 May 22;290(21):13157-67.
Title: Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
Author: Tirodkar, Tejas S|Lu, Ping|Bai, Aiping|Scheffel, Matthew J|Gencer, Salih|Garrett-Mayer, Elizabeth|Bielawska, Alicja|Ogretmen, Besim|Voelkel-Johnson, Christina
PMID: 25839235
Journal: Oncol Rep. 2015 Jul;34(1):447-54.
Title: Endocannabinoid and ceramide levels are altered in patients with colorectal cancer.
Author: Chen, Ling|Chen, Huixia|Li, Yanting|Li, Lei|Qiu, Yan|Ren, Jie
PMID: 25975960
Journal: BMC Med Genomics. 2016 Sep 8;9(1):58.
Title: A 19-Gene expression signature as a predictor of survival in colorectal cancer.
Author: Abdul Aziz, Nurul Ainin|Mokhtar, Norfilza M|Harun, Roslan|Mollah, Md Manir Hossain|Mohamed Rose, Isa|Sagap, Ismail|Mohd Tamil, Azmi|Wan Ngah, Wan Zurinah|Jamal, Rahman
PMID: 27609023
Journal: Oncol Rep. 2018 Sep 18.
Title: Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer.
Author: Jang, Sung Won|Park, Woo-Jae|Min, Hyeonji|Kwon, Taeg Kyu|Baek, Seong Kyu|Hwang, Ilseon|Kim, Shin|Park, Jong-Wook
PMID: 30272337