Primary Site >> Biliary tract Cancer

Gene >> CDH17

Journal: Hepatology. 1998 Apr;27(4):974-82.
Title: Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study.
Author: Ashida, K|Terada, T|Kitamura, Y|Kaibara, N
PMID: 9537436
Journal: Cancer Res. 2001 Apr 15;61(8):3406-9.
Title: Beta-catenin mutations in biliary tract cancers: a population-based study in China.
Author: Rashid, A|Gao, Y T|Bhakta, S|Shen, M C|Wang, B S|Deng, J|Fraumeni, J F Jr|Hsing, A W
PMID: 11309300
Journal: Mod Pathol. 2001 Sep;14(9):900-5.
Title: Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma.
Author: Sugimachi, K|Taguchi, K|Aishima, S|Tanaka, S|Shimada, M|Kajiyama, K|Sugimachi, K|Tsuneyoshi, M
PMID: 11557787
Journal: Liver. 2002 Feb;22(1):43-50.
Title: The mode of tumour progression in combined hepatocellular carcinoma and cholangiocarcinoma: an immunohistochemical analysis of E-cadherin, alpha-catenin and beta-catenin.
Author: Asayama, Yoshiki|Taguchi Ki, Ken-ichi|Aishima Si, Shin-ichi|Nishi, Hidehiro|Masuda, Kouji|Tsuneyoshi, Masazumi
PMID: 11906618
Journal: Br J Cancer. 2002 Jul 15;87(2):187-93.
Title: Establishment and characterisation of six human biliary tract cancer cell lines.
Author: Ku, J-L|Yoon, K-A|Kim, I-J|Kim, W-H|Jang, J-Y|Suh, K-S|Kim, S-W|Park, Y-H|Hwang, J-H|Yoon, Y-B|Park, J-G
PMID: 12107841
Journal: Ann Surg Oncol. 2005 May;12(5):354-63. Epub 2005 Mar 31.
Title: Tumor progression through epigenetic gene silencing of O(6)-methylguanine-DNA methyltransferase in human biliary tract cancers.
Author: Koga, Yasuo|Kitajima, Yoshihiko|Miyoshi, Atsushi|Sato, Ken|Kitahara, Kenji|Soejima, Hidenobu|Miyazaki, Kohji
PMID: 15915369
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4249-54.
Title: E-cadherin and beta-catenin expression in normal, inflamed and cancerous gallbladder tissue.
Author: Puhalla, Harald|Herberger, Beate|Soleiman, Afschin|Filipits, Martin|Laengle, Fritz|Gruenberger, Thomas|Wrba, Fritz
PMID: 16309224
Journal: J Clin Pathol. 2005 Dec;58(12):1249-54.
Title: FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma.
Author: Settakorn, J|Kaewpila, N|Burns, G F|Leong, A S-Y
PMID: 16311342
Journal: Hepatogastroenterology. 2006 Jan-Feb;53(67):28-32.
Title: Expression of E-cadherin and beta-catenin in the adenoma-carcinoma sequence of ampulla of Vater cancer.
Author: Park, Sunhoo|Kim, Sun Whe|Lee, Byung Lan|Jung, Eun Ji|Kim, Woo Ho
PMID: 16506371
Journal: Cancer Res. 2006 Jul 1;66(13):6622-7.
Title: Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice.
Author: Farazi, Paraskevi A|Zeisberg, Michael|Glickman, Jonathan|Zhang, Yan|Kalluri, Raghu|DePinho, Ronald A
PMID: 16818635
Journal: Virchows Arch. 2006 Nov;449(5):585-90.
Title: Intrahepatic sarcomatoid cholangiocarcinoma of round cell variant: a case report and immunohistochemical studies.
Author: Sato, Katsuaki|Murai, Hiroshi|Ueda, Yoshimichi|Katsuda, Shogo
PMID: 17033799
Journal: Liver Int. 2007 Nov;27(9):1174-84.
Title: Immunohistochemical analysis of the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis.
Author: Itatsu, Keita|Zen, Yoh|Ohira, Shusaku|Ishikawa, Akira|Sato, Yasunori|Harada, Kenichi|Ikeda, Hiroko|Sasaki, Motoko|Nimura, Yuji|Nakanuma, Yasuni
PMID: 17919228
Journal: Cancer Sci. 2008 Sep;99(9):1785-92.
Title: Bile acids repress E-cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma.
Author: Fukase, Koji|Ohtsuka, Hideo|Onogawa, Tohru|Oshio, Hiroshi|Ii, Takayuki|Mutoh, Mitsuhisa|Katayose, Yu|Rikiyama, Toshiki|Oikawa, Masaya|Motoi, Fuyuhiko|Egawa, Shinichi|Abe, Takaaki|Unno, Michiaki
PMID: 18691339
Journal: FEBS Lett. 2009 Jan 22;583(2):430-6.
Title: Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancer.
Author: Adachi, Yoshihiro|Takeuchi, Tamotsu|Nagayama, Tomoko|Ohtsuki, Yuji|Furihata, Mutsuo
PMID: 19116147
Journal: FEBS Lett. 2009 Jan 22;583(2):430-6.
Title: Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancer.
Author: Adachi, Yoshihiro|Takeuchi, Tamotsu|Nagayama, Tomoko|Ohtsuki, Yuji|Furihata, Mutsuo
PMID: 20309424
Journal: Int J Oncol. 2010 Jan;36(1):49-58.
Title: Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition.
Author: Kiesslich, Tobias|Alinger, Beate|Wolkersdorfer, Gernot W|Ocker, Matthias|Neureiter, Daniel|Berr, Frieder
PMID: 19956832
Journal: Int J Oncol. 2010 Jan;36(1):245-54.
Title: Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma promotes angiogenesis by up-regulating metal-responsive transcription factor-1 and placental growth factor.
Author: Takamura, Masaaki|Yamagiwa, Satoshi|Wakai, Toshifumi|Tamura, Yasushi|Kamimura, Hiroteru|Kato, Takashi|Tsuchiya, Atsunori|Matsuda, Yasunobu|Shirai, Yoshio|Ichida, Takafumi|Ajioka, Yoichi|Aoyagi, Yutaka
PMID: 19956853
Journal: J Surg Oncol. 2010 Apr 1;101(5):356-62.
Title: Loss of E-cadherin and beta-catenin is correlated with poor prognosis of ampullary neoplasms.
Author: Hsu, Hui-Ping|Shan, Yan-Shen|Jin, Ying-Tai|Lai, Ming-Derg|Lin, Pin-Wen
PMID: 20119975
Journal: World J Gastroenterol. 2010 Feb 14;16(6):713-22.
Title: Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion.
Author: Menakongka, Apaporn|Suthiphongchai, Tuangporn
PMID: 20135719
Journal: Am J Pathol. 2010 Jul;177(1):141-52.
Title: Epithelial-mesenchymal transition induced by transforming growth factor-{beta}1/Snail activation aggravates invasive growth of cholangiocarcinoma.
Author: Sato, Yasunori|Harada, Kenichi|Itatsu, Keita|Ikeda, Hiroko|Kakuda, Yuko|Shimomura, Syuji|Shan Ren, Xiang|Yoneda, Norihide|Sasaki, Motoko|Nakanuma, Yasuni
PMID: 20489148
Journal: Anat Cell Biol. 2010 Jun;43(2):110-7.
Title: CDH3/P-Cadherin regulates migration of HuCCT1 cholangiocarcinoma cells.
Author: Baek, Sungmin|Lee, Yong-Whan|Yoon, Sik|Baek, Sun-Yong|Kim, Bong-Seon|Oh, Sae-Ock
PMID: 21189991
Journal: Hepatogastroenterology. 2011 Nov-Dec;58(112):2045-51.
Title: Liver-intestine cadherin in intraepithelial neoplasia of intrahepatic cholangiocarcinoma.
Author: Inoue, Makoto|Ajioka, Yoichi|Wakai, Toshifumi|Takamura, Masaaki|Korita, Pavel|Shirai, Yoshio|Hatakeyama, Katsuyoshi
PMID: 22024075
Journal: Br J Cancer. 2011 Dec 6;105(12):1885-93.
Title: E/N-cadherin switch mediates cancer progression via TGF-beta-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma.
Author: Araki, K|Shimura, T|Suzuki, H|Tsutsumi, S|Wada, W|Yajima, T|Kobayahi, T|Kubo, N|Kuwano, H
PMID: 22068819
Journal: Med Oncol. 2012 Dec;29(5):3083-91.
Title: Tumor necrosis factor-alpha (TNF-alpha) stimulates the epithelial-mesenchymal transition regulator Snail in cholangiocarcinoma.
Author: Techasen, Anchalee|Namwat, Nisana|Loilome, Watcharin|Bungkanjana, Pornpan|Khuntikeo, Narong|Puapairoj, Anucha|Jearanaikoon, Patcharee|Saya, Hideyuki|Yongvanit, Puangrat
PMID: 22903530
Journal: Int J Oncol. 2012 Aug;41(2):573-82.
Title: Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma.
Author: Okamoto, Koichi|Tajima, Hidehiro|Nakanuma, Shinichi|Sakai, Seisho|Makino, Isamu|Kinoshita, Jun|Hayashi, Hironori|Nakamura, Keishi|Oyama, Katsunobu|Nakagawara, Hisatoshi|Fujita, Hideto|Takamura, Hiroyuki|Ninomiya, Itasu|Kitagawa, Hirohisa|Fushida, Sachio|F
PMID: 22664794
Journal: FEBS J. 2012 Jul;279(13):2393-8.
Title: Down-regulation of miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist.
Author: Li, Bin|Han, Qingqi|Zhu, Yan|Yu, Yong|Wang, Jinghan|Jiang, Xiaoqing
PMID: 22540680
Journal: Hepatogastroenterology. 2012 Jun;59(116):1241-4.
Title: Clinicopathological significance of E-cadherin, beta-catenin and epidermal growth factor receptor expression in intrahepatic cholangiocarcinoma.
Author: Gu, Mi Jin|Choi, Joon Hyuk
PMID: 22281980
Journal: Oncol Rep. 2012 Mar;27(3):775-82.
Title: Establishment and characterization of a cell line, EH-GB2, derived from hepatic metastasis of gallbladder cancer.
Author: Wang, Jing-Han|Li, Lin-Fang|Yu, Yong|Li, Bin|Jin, Hua-Jun|Shen, Dong-Hao|Li, Jiang|Jiang, Xiao-Qing|Qian, Qi-Jun
PMID: 22134783
Journal: Cancer Sci. 2012 Jun;103(6):1165-71.
Title: Significance of epithelial growth factor in the epithelial-mesenchymal transition of human gallbladder cancer cells.
Author: Sasaki, Takamitsu|Kuniyasu, Hiroki|Luo, Yi|Kato, Daisuke|Shinya, Satoshi|Fujii, Kiyomu|Ohmori, Hitoshi|Yamashita, Yuichi
PMID: 22404757
Journal: J Clin Pathol. 2014 Mar;67(3):229-34.
Title: Epithelial-mesenchymal transition phenotypes are associated with patient survival in intrahepatic cholangiocarcinoma.
Author: Gu, Mi Jin|Choi, Joon Hyuk
PMID: 24062361
Journal: Tumour Biol. 2014 Apr;35(4):3103-12.
Title: Decorin-mediated inhibition of cholangiocarcinoma cell growth and migration and promotion of apoptosis are associated with E-cadherin in vitro.
Author: Yu, Xiang|Zou, Yanfen|Li, Quan|Mao, Yonghuan|Zhu, Hui|Huang, Guangming|Ji, Guozhong|Luo, Xiagang|Yu, Chunzhao|Zhang, Xiuhua
PMID: 24272200
Journal: Gut Liver. 2014 Jan;8(1):94-101.
Title: Differential expression of E-cadherin, beta-catenin, and S100A4 in intestinal type and nonintestinal type ampulla of Vater cancers.
Author: Sung, Rohyun|Kang, Li|Han, Joung-Ho|Choi, Jae-Woon|Lee, Sang Hwa|Lee, Tae Hoon|Park, Sang-Heum|Kim, Hong Ja|Lee, Eaum Seok|Kim, Young Suk|Choi, Young Woo|Park, Seon Mee
PMID: 24516707
Journal: J Hepatol. 2014 Aug;61(2):325-32.
Title: EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.
Author: Claperon, Audrey|Mergey, Martine|Nguyen Ho-Bouldoires, Thanh Huong|Vignjevic, Danijela|Wendum, Dominique|Chretien, Yves|Merabtene, Fatiha|Frazao, Alexandra|Paradis, Valerie|Housset, Chantal|Guedj, Nathalie|Fouassier, Laura
PMID: 24704591
Journal: PLoS One. 2014 May 9;9(5):e96860.
Title: Comprehensive multiple molecular profile of epithelial mesenchymal transition in intrahepatic cholangiocarcinoma patients.
Author: Huang, Xiao-Yong|Zhang, Chi|Cai, Jia-Bin|Shi, Guo-Ming|Ke, Ai-Wu|Dong, Zhao-Ru|Zhang, Peng-Fei|Fan, Jia|Peng, Bao-Gang|Zhou, Jian
PMID: 24816558
Journal: Tumour Biol. 2014 Sep;35(9):8645-52.
Title: Loss of E-cadherin promotes migration and invasion of cholangiocarcinoma cells and serves as a potential marker of metastasis.
Author: Techasen, Anchalee|Loilome, Watcharin|Namwat, Nisana|Khuntikeo, Narong|Puapairoj, Anucha|Jearanaikoon, Patcharee|Saya, Hideyuki|Yongvanit, Puangrat
PMID: 24867095
Journal: Tumour Biol. 2014 Oct;35(10):9667-76.
Title: BMP-7 blocks the effects of TGF-beta-induced EMT in cholangiocarcinoma.
Author: Duangkumpha, Kassaporn|Techasen, Anchalee|Loilome, Watcharin|Namwat, Nisana|Thanan, Raynoo|Khuntikeo, Narong|Yongvanit, Puangrat
PMID: 24969562
Journal: PLoS One. 2014 Jul 10;9(7):e102084.
Title: Forkhead box L1 is frequently downregulated in gallbladder cancer and inhibits cell growth through apoptosis induction by mitochondrial dysfunction.
Author: Qin, Yiyu|Gong, Wei|Zhang, Mingdi|Wang, Jiandong|Tang, Zhaohui|Quan, Zhiwei
PMID: 25010679
Journal: Br J Cancer. 2014 Sep 23;111(7):1363-72.
Title: Prognostic significance of epithelial-mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray.
Author: Nitta, T|Mitsuhashi, T|Hatanaka, Y|Miyamoto, M|Oba, K|Tsuchikawa, T|Suzuki, Y|Hatanaka, K C|Hirano, S|Matsuno, Y
PMID: 25077440
Journal: Oncol Lett. 2014 Oct;8(4):1687-1692. Epub 2014 Jul 11.
Title: Signet ring cell carcinoma of the ampulla of Vater: Immunophenotype and differentiation.
Author: Wen, Xue|Wu, Weiqiang|Wang, Bo|Yao, Hongtian|Teng, Xiaodong
PMID: 25202392
Journal: Asian Pac J Cancer Prev. 2015;16(7):3043-50.
Title: Quantitative changes in tumor-associated M2 macrophages characterize cholangiocarcinoma and their association with metastasis.
Author: Thanee, Malinee|Loilome, Watcharin|Techasen, Anchalee|Namwat, Nisana|Boonmars, Thidarut|Pairojkul, Chawalit|Yongvanit, Puangrat
PMID: 25854403
Journal: Biochim Biophys Acta. 2015 Sep;1852(9):1989-99.
Title: Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.
Author: Dutta, Suman|Reamtong, Onrapak|Panvongsa, Wittaya|Kitdumrongthum, Sarunya|Janpipatkul, Keatdamrong|Sangvanich, Polkit|Piyachaturawat, Pawinee|Chairoungdua, Arthit
PMID: 26148937
Journal: Oncol Rep. 2015 Aug;34(2):610-6.
Title: Adrenomedullin promotes intrahepatic cholangiocellular carcinoma metastasis and invasion by inducing epithelial-mesenchymal transition.
Author: Zhou, Chuang|Zheng, Yan|Li, Lin|Zhai, Wenlong|Li, Renfeng|Liang, Zhiwen|Zhao, Longshuan
PMID: 26043778
Journal: Stem Cells. 2015 Dec;33(12):3569-80.
Title: Osteopontin Promotes Hepatic Progenitor Cell Expansion and Tumorigenicity via Activation of beta-Catenin in Mice.
Author: Liu, Yingying|Cao, Lei|Chen, Rui|Zhou, Xuyu|Fan, Xiaoyu|Liang, Yingchao|Jia, Rongjie|Wang, Hao|Liu, Guoke|Guo, Yajun|Zhao, Jian
PMID: 26033745
Journal: Med Oncol. 2015 Apr;32(4):105.
Title: Enhanced expression of suppresser of cytokine signaling 3 inhibits the IL-6-induced epithelial-to-mesenchymal transition and cholangiocarcinoma cell metastasis.
Author: Zhou, Qing-Xin|Jiang, Xing-Ming|Wang, Zhi-Dong|Li, Chun-Long|Cui, Yun-Fu
PMID: 25744243
Journal: Technol Cancer Res Treat. 2016 Apr;15(2):322-33.
Title: Fascin Overexpression Promotes Cholangiocarcinoma RBE Cell Proliferation, Migration, and Invasion.
Author: Zhao, Haiying|Yang, Fuquan|Zhao, Wenyan|Zhang, Chunjv|Liu, Jingang
PMID: 25882880
Journal: Dig Dis Sci. 2016 Jul;61(7):1950-60.
Title: WAVE3 Induces EMT and Promotes Migration and Invasion in Intrahepatic Cholangiocarcinoma.
Author: Zhu, Zebin|Chen, Wei|Yin, Xiaoyu|Lai, Jiaming|Wang, Qian|Liang, Lijian|Wang, Wei|Wang, Anxun|Zheng, Chaoxu
PMID: 26971088
Journal: Am J Cancer Res. 2015 Dec 15;6(1):15-26. eCollection 2016.
Title: Upregulation of H19 indicates a poor prognosis in gallbladder carcinoma and promotes epithelial-mesenchymal transition.
Author: Wang, Shou-Hua|Wu, Xiao-Cai|Zhang, Ming-Di|Weng, Ming-Zhe|Zhou, Di|Quan, Zhi-Wei
PMID: 27073719
Journal: J Clin Pathol. 2017 Aug;70(8):677-683.
Title: Mortalin promotes cell proliferation and epithelial mesenchymal transition of intrahepatic cholangiocarcinoma cells in vitro.
Author: Kang, Qiang|Cai, Jia-Bin|Dong, Rui-Zhao|Liu, Li-Xin|Zhang, Chi|Zhang, Peng-Fei|Zou, Hao|Xie, Nan|Zhang, Lu|Zhang, Xin-Yu|Song, Zheng-Ji|Dong, Zhao-Ru|Hu, Mei-Yu|Huang, Xiao-Yong|Zhang, Xiao-Wen|Ke, Ai-Wu|Shi, Guo-Ming
PMID: 28096273
Journal: Oncotarget. 2017 Jul 18;8(29):47052-47063.
Title: TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT.
Author: Li, Xinxing|Teng, Shifeng|Zhang, Yanyan|Zhang, Weigang|Zhang, Xianwen|Xu, Kai|Yao, Houshan|Yao, Jun|Wang, Haolu|Liang, Xiaowen|Hu, Zhiqian
PMID: 28423362
Journal: Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3806-E3815.
Title: Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands.
Author: Nakagawa, Hayato|Suzuki, Nobumi|Hirata, Yoshihiro|Hikiba, Yohko|Hayakawa, Yoku|Kinoshita, Hiroto|Ihara, Sozaburo|Uchino, Koji|Nishikawa, Yuji|Ijichi, Hideaki|Otsuka, Motoyuki|Arita, Junichi|Sakamoto, Yoshihiro|Hasegawa, Kiyoshi|Kokudo, Norihiro|Tateishi,
PMID: 28439013
Journal: Oncotarget. 2017 Jul 25;8(30):49897-49914.
Title: Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- beta1-SMAD3-ID1 signaling pathway.
Author: Liu, Zhong-Yan|Cao, Jin|Zhang, Jing-Tao|Xu, Guo-Li|Li, Xin-Ping|Wang, Fang-Tao|Ansari, Kamar Hasan|Mohamed, Hassan|Fan, Yue-Zu
PMID: 28611292
Journal: Cancer Cell Int. 2017 Sep 26;17:85.
Title: Blocking ERK1/2 signaling impairs TGF-beta1 tumor promoting function but enhances its tumor suppressing role in intrahepatic cholangiocarcinoma cells.
Author: Sritananuwat, Phaijit|Sueangoen, Natthaporn|Thummarati, Parichut|Islam, Kittiya|Suthiphongchai, Tuangporn
PMID: 28959141
Journal: J Transl Med. 2018 Mar 6;16(1):50.
Title: CD133 expression in cancer cells predicts poor prognosis of non-mucin producing intrahepatic cholangiocarcinoma.
Author: Cai, Xiaobo|Li, Jun|Yuan, Xiaodong|Xiao, Jingbo|Dooley, Steven|Wan, Xinjian|Weng, Honglei|Lu, Lungen
PMID: 29510695
Journal: Future Oncol. 2018 Apr;14(9):837-847.
Title: S100A11 promotes TGF-beta1-induced epithelial-mesenchymal transition through SMAD2/3 signaling pathway in intrahepatic cholangiocarcinoma.
Author: Zhang, Meixia|Zheng, Susu|Jing, Chuyu|Zhang, Juan|Shen, Hujia|Xu, Xin|Lin, Jiajia|Zhang, Boheng
PMID: 29569474
Journal: Zhonghua Wai Ke Za Zhi. 2018 Aug 1;56(8):617-622.
Title: [Kindlin-2 promotes gallbladder cancer metastasis and invasion by inducing epithelial-mesenchymal transition].
Author: Lu, X|Zhou, C|Li, R F|Ye, J W|Zhai, W L
PMID: 30107706