Primary Site >> Liver Cancer

Gene >> CDC25C

Journal: Hepatology. 2001 Feb;33(2):346-56.
Title: Interferon-alpha delays S-phase progression in human hepatocellular carcinoma cells via inhibition of specific cyclin-dependent kinases.
Author: Murphy, D|Detjen, K M|Welzel, M|Wiedenmann, B|Rosewicz, S
PMID: 11172336
Journal: Int J Cancer. 2002 Jul 10;100(2):158-65.
Title: Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells.
Author: Chen, Yan-Nian|Chen, Jung-Chou|Yin, Sui-Chu|Wang, Guang-Sheng|Tsauer, Wei|Hsu, Sheng-Feng|Hsu, Shih-Lan
PMID: 12115564
Journal: Biochem Pharmacol. 2004 Feb 15;67(4):717-26.
Title: Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.
Author: Chang, Kee-Lung|Kung, Mei-Lang|Chow, Nan-Haw|Su, Shu-Jem
PMID: 14757171
Journal: Cancer Lett. 2006 Jun 18;237(2):188-98.
Title: Elevated phosphorylation of Chk1 and decreased phosphorylation of Chk2 are associated with abrogation of G2/M checkpoint control during transformation of Syrian hamster embryo (SHE) cells by Malachite green.
Author: Ashra, Hima|Rao, K V K
PMID: 16085357
Journal: Biochem Biophys Res Commun. 2006 Feb 17;340(3):758-66.
Title: Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.
Author: Chen, Yongxin|Guo, Yingqiu|Ge, Xijin|Itoh, Hirotaka|Watanabe, Akira|Fujiwara, Takeshi|Kodama, Tatsuhiko|Aburatani, Hiroyuki
PMID: 16380080
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2006 Dec;374(3):223-33.
Title: Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
Author: Lu, Pin-Hsuan|Kung, Fan-Lu|Kuo, Sheng-Chu|Chueh, Shih-Chieh|Guh, Jih-Hwa
PMID: 17102938
Journal: Phytother Res. 2007 Jan;21(1):52-7.
Title: Methanol extract of the seaweed Gloiopeltis furcata induces G2/M arrest and inhibits cyclooxygenase-2 activity in human hepatocarcinoma HepG2 cells.
Author: Bae, Song Ja|Choi, Yung Hyun
PMID: 17078109
Journal: Biochem Pharmacol. 2007 Jun 30;74(1):10-9.
Title: Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
Author: Chen, Ying-Cheng|Lu, Pin-Hsuan|Pan, Shiow-Lin|Teng, Che-Ming|Kuo, Sheng-Chu|Lin, Tsung-Ping|Ho, Yunn-Fang|Huang, Yu-Chun|Guh, Jih-Hwa
PMID: 17475221
Journal: J Cell Biochem. 2008 Jul 1;104(4):1181-91.
Title: Involvement of the role of Chk1 in lithium-induced G2/M phase cell cycle arrest in hepatocellular carcinoma cells.
Author: Wang, Xiao-Ming|Li, Jiao|Feng, Xiao-Cheng|Wang, Qiong|Guan, Dong-Yin|Shen, Zong-Hou
PMID: 18247328
Journal: J Gastroenterol Hepatol. 2008 Jul;23(7 Pt 2):e290-9.
Title: Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo.
Author: Hsu, Ya-Ling|Kuo, Po-Lin|Tzeng, Tz-Fei|Sung, Shu-Chiao|Yen, Ming-Hong|Lin, Liang-Tzung|Lin, Chun-Ching
PMID: 18522681
Journal: J Agric Food Chem. 2009 Aug 26;57(16):7331-7.
Title: Magnolol inhibits human glioblastoma cell proliferation through upregulation of p21/Cip1.
Author: Chen, Li-Ching|Liu, Yu-Chi|Liang, Yu-Chih|Ho, Yuan-Soon|Lee, Wen-Sen
PMID: 19645506
Journal: Anticancer Drugs. 2009 Nov;20(10):926-31.
Title: Anticancer activity and mechanisms of diacetyldianhydrogalactitol on hepatoma QGY-7703 cells.
Author: Zhang, Xue Yan|Lian Yan, Xue|Guo, Wei|Xu, Bo|Li, Min|Zhou, Ying|Rong Cui, Jing
PMID: 19741503
Journal: Cancer Lett. 2010 Feb 28;288(2):204-13.
Title: Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation.
Author: Moon, Dong-Oh|Kim, Mun-Ock|Choi, Yung Hyun|Hyun, Jin Won|Chang, Weon Young|Kim, Gi-Young
PMID: 19643530
Journal: Hepatology. 2010 Jun;51(6):2008-19.
Title: Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro.
Author: Yu, Jun|Shen, Bo|Chu, Eagle S H|Teoh, Narci|Cheung, Kin-Fai|Wu, Chung-Wah|Wang, Shiyan|Lam, Cleo N Y|Feng, Hai|Zhao, Junhong|Cheng, Alfred S L|To, Ka-Fai|Chan, Henry L Y|Sung, Joseph J Y
PMID: 20512989
Journal: J Hematol Oncol. 2010 Oct 31;3:43.
Title: Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells.
Author: Wu, Qiong|Qin, Shu-Kui|Teng, Feng-Meng|Chen, Chang-Jie|Wang, Rui
PMID: 21034513
Journal: J Sci Food Agric. 2011 Jan 15;91(1):178-85.
Title: Solanum nigrum L. polyphenolic extract inhibits hepatocarcinoma cell growth by inducing G2/M phase arrest and apoptosis.
Author: Wang, Hsueh-Chun|Chung, Pei-Jun|Wu, Cheng-Hsun|Lan, Kuang-Ping|Yang, Mon-Yuan|Wang, Chau-Jong
PMID: 20853273
Journal: Radiat Oncol. 2011 May 30;6:56.
Title: Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells.
Author: Liu, Chia-Yuan|Chang, Hsun-Shuo|Chen, Ih-Sheng|Chen, Chih-Jen|Hsu, Ming-Ling|Fu, Shu-Ling|Chen, Yu-Jen
PMID: 21624128
Journal: Int J Oncol. 2012 Oct;41(4):1431-42.
Title: Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells.
Author: Tsai, Shih-Chang|Yang, Jai-Sing|Peng, Shu-Fen|Lu, Chi-Cheng|Chiang, Jo-Hua|Chung, Jing-Gung|Lin, Meng-Wei|Lin, Jen-Kun|Amagaya, Sakae|Wai-Shan Chung, Cinderella|Tung, Theng-Thang|Huang, Wen-Wen|Tseng, Michael T
PMID: 22858649
Journal: PLoS One. 2012;7(5):e36808.
Title: Isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/m cell cycle arrest and apoptosis.
Author: Sun, Hefen|Hou, Helei|Lu, Ping|Zhang, Lixing|Zhao, Fangyu|Ge, Chao|Wang, Tingpu|Yao, Ming|Li, Jinjun
PMID: 22623962
Journal: Biochem Pharmacol. 2012 May 1;83(9):1278-89.
Title: Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo.
Author: Zhang, Chris Zhiyi|Zhang, Haitao|Yun, Jingping|Chen, George Gong|Lai, Paul Bo San
PMID: 22342732
Journal: Hepatology. 2012 Feb;55(2):491-505.
Title: Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development.
Author: Chan, Tim Hon Man|Chen, Leilei|Liu, Ming|Hu, Liang|Zheng, Bo-jian|Poon, Vincent Kwok-Man|Huang, Pinzhu|Yuan, Yun-Fei|Huang, Jian-dong|Yang, Jie|Tsao, George Sai-wah|Guan, Xin-Yuan
PMID: 21953552
Journal: PLoS One. 2012;7(2):e31655.
Title: A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma.
Author: Ng, Kevin T P|Guo, Dong Yong|Cheng, Qiao|Geng, Wei|Ling, Chang Chun|Li, Chang Xian|Liu, Xiao Bing|Ma, Yuen Yuen|Lo, Chung Mau|Poon, Ronnie T P|Fan, Sheung Tat|Man, Kwan
PMID: 22389672
Journal: BMC Cancer. 2013 Mar 28;13:167.
Title: UCN-01 induces S and G2/M cell cycle arrest through the p53/p21(waf1) or CHK2/CDC25C pathways and can suppress invasion in human hepatoma cell lines.
Author: Wu, Guoyi|Lin, Nan|Xu, Linan|Liu, Bo|Feitelson, Mark A
PMID: 23537372
Journal: Phytomedicine. 2013 May 15;20(7):640-7.
Title: Lignans extracted from Vitex negundo possess cytotoxic activity by G2/M phase cell cycle arrest and apoptosis induction.
Author: Xin, Hong|Kong, Ying|Wang, Yong|Zhou, Yingjun|Zhu, Yizhun|Li, Dapeng|Tan, Wenfu
PMID: 23562365
Journal: J Biol Chem. 2013 Jul 12;288(28):20532-46.
Title: 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.
Author: Chaudhary, Pankaj|Sharma, Rajendra|Sahu, Mukesh|Vishwanatha, Jamboor K|Awasthi, Sanjay|Awasthi, Yogesh C
PMID: 23733185
Journal: Oncol Rep. 2013 Nov;30(5):2467-75.
Title: Dihydromyricetin suppresses the proliferation of hepatocellular carcinoma cells by inducing G2/M arrest through the Chk1/Chk2/Cdc25C pathway.
Author: Huang, Haili|Hu, Min|Zhao, Rui|Li, Peng|Li, Mingyi
PMID: 24002546
Journal: BioData Min. 2013 Oct 15;6(1):17.
Title: Using random walks to identify cancer-associated modules in expression data.
Author: Petrochilos, Deanna|Shojaie, Ali|Gennari, John|Abernethy, Neil
PMID: 24128261
Journal: Chem Biol Interact. 2014 Aug 5;219:184-94.
Title: Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.
Author: Deng, Li-Juan|Hu, Li-Ping|Peng, Qun-Long|Yang, Xiao-Lin|Bai, Liang-Liang|Yiu, Anita|Li, Yong|Tian, Hai-Yan|Ye, Wen-Cai|Zhang, Dong-Mei
PMID: 24954031
Journal: Asian Pac J Cancer Prev. 2014;15(7):3293-7.
Title: Inhibitory effects of alpha-pinene on hepatoma carcinoma cell proliferation.
Author: Chen, Wei-Qiang|Xu, Bin|Mao, Jian-Wen|Wei, Feng-Xiang|Li, Ming|Liu, Tao|Jin, Xiao-Bao|Zhang, Li-Rong
PMID: 24815485
Journal: FEBS J. 2014 Feb;281(3):851-61.
Title: Oncogenic potential of CK2alpha and its regulatory role in EGF-induced HDAC2 expression in human liver cancer.
Author: Kim, Hyung S|Chang, Young G|Bae, Hyun J|Eun, Jung W|Shen, Qingyu|Park, Se J|Shin, Woo C|Lee, Eun K|Park, Soha|Ahn, Young M|Park, Won S|Lee, Jung Y|Nam, Suk W
PMID: 24616922
Journal: Oncol Rep. 2015 Aug;34(2):823-32.
Title: USP39 promotes the growth of human hepatocellular carcinoma in vitro and in vivo.
Author: Yuan, Xianwen|Sun, Xitai|Shi, Xiaolei|Jiang, Chunping|Yu, Decai|Zhang, Weiwei|Guan, Wenxian|Zhou, Jianxin|Wu, Yafu|Qiu, Yudong|Ding, Yitao
PMID: 26081192
Journal: Biomed Pharmacother. 2015 Dec;76:141-6.
Title: The tumor-suppressor gene LZTS1 suppresses hepatocellular carcinoma proliferation by impairing PI3K/Akt pathway.
Author: He, Yonghong|Liu, Xia
PMID: 26653561
Journal: Zhongguo Zhong Yao Za Zhi. 2015 Dec;40(24):4897-902.
Title: [Oleanolic acid induces G(2)/M phase arrest and apoptosis in human hepatocellular carcinoma Bel-7402 cells].
Author: Liu, Ling|Zhao, Jian-long|Wang, Jian-gang
PMID: 27245040
Journal: J BUON. 2016 Jul-Aug;21(4):917-924.
Title: Inhibitory effects of Silibinin combined with doxorubicin in hepatocellular carcinoma; an in vivo study.
Author: Li, Wei-Guo|Wang, He-Qun
PMID: 27685914
Journal: Sci Rep. 2016 Dec 2;6:38072.
Title: Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition.
Author: Huang, Zhizhou|Zhou, Xueqiong|He, Yangfan|Ke, Xiangyu|Wen, Ying|Zou, Fei|Chen, Xuemei
PMID: 27909289
Journal: Biochem Pharmacol. 2017 Mar 1;127:90-100.
Title: Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells.
Author: Sun, Wei-Jian|Huang, He|He, Bin|Hu, Dan-Hong|Li, Pi-Hong|Yu, Yao-Jun|Zhou, Xiao-Hu|Lv, Zhen|Zhou, Lei|Hu, Tian-Ye|Yao, Zhi-Chao|Lu, Ming-Dong|Shen, Xian|Zheng, Zhi-Qiang
PMID: 28012958
Journal: Int J Oncol. 2017 Feb;50(2):575-586.
Title: Korean Byungkyul - Citrus platymamma Hort.et Tanaka flavonoids induces cell cycle arrest and apoptosis, regulating MMP protein expression in Hep3B hepatocellular carcinoma cells.
Author: Hong, Gyeong Eun|Lee, Ho Jeong|Kim, Jin A|Yumnam, Silvia|Raha, Suchismita|Venkatarame Gowda Saralamma, Venu|Heo, Jeong Doo|Lee, Sang Joon|Kim, Eun Hee|Won, Chun Kil|Kim, Gon Sup
PMID: 28035361
Journal: Evid Based Complement Alternat Med. 2017;2017:8231936.
Title: Ethanol Extract of Root of Prunus persica Inhibited the Growth of Liver Cancer Cell HepG2 by Inducing Cell Cycle Arrest and Migration Suppression.
Author: Shen, Hongchun|Wang, Honglian|Wang, Li|Wang, Lu|Zhu, Menglian|Ming, Yao|Zhao, Sha|Fan, Junming|Lai, En Yin
PMID: 29234432
Journal: Onco Targets Ther. 2018 Feb 2;11:689-702.
Title: Overexpression of Zwint predicts poor prognosis and promotes the proliferation of hepatocellular carcinoma by regulating cell-cycle-related proteins.
Author: Ying, Hanning|Xu, Zhiyao|Chen, Mingming|Zhou, Senjun|Liang, Xiao|Cai, Xiujun
PMID: 29440916
Journal: Onco Targets Ther. 2018 Feb 26;11:983-996.
Title: Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway.
Author: Yang, Chendong|Hou, Aihua|Yu, Chunfeng|Dai, Lingling|Wang, Wen|Zhang, Kangle|Shao, Hongmin|Ma, Jinghua|Xu, Wenjuan
PMID: 29520149