Primary Site >> Colorectal Cancer
Gene >> CDAN1
| 1. | |||||||||||
| Journal: | J Clin Oncol. 1995 Sep;13(9):2230-7. | ||||||||||
| Title: | Phase I study of paclitaxel and topotecan in patients with advanced tumors: a cancer and leukemia group B study. | ||||||||||
| Author: | Lilenbaum, R C|Ratain, M J|Miller, A A|Hargis, J B|Hollis, D R|Rosner, G L|O'Brien, S M|Brewster, L|Green, M R|Schilsky, R L | ||||||||||
| PMID: | 7545219 | ||||||||||
| 2. | |||||||||||
| Journal: | Clin Cancer Res. 1997 Mar;3(3):409-17. | ||||||||||
| Title: | Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. | ||||||||||
| Author: | Atkins, M B|Robertson, M J|Gordon, M|Lotze, M T|DeCoste, M|DuBois, J S|Ritz, J|Sandler, A B|Edington, H D|Garzone, P D|Mier, J W|Canning, C M|Battiato, L|Tahara, H|Sherman, M L | ||||||||||
| PMID: | 9815699 | ||||||||||
| 3. | |||||||||||
| Journal: | Ann Oncol. 1998 Dec;9(12):1309-14. | ||||||||||
| Title: | 5-methyltetrahydrofolate for biochemical modulation of fluorouracil (FU) in patients with advanced colorectal cancer: a randomized phase I-II study of two different FU administration schedules. | ||||||||||
| Author: | Hejna, M|Kornek, G V|Raderer, M|Valencak, J|Weinlander, G|Fiebiger, W|Miholic, J|Scheithauer, W | ||||||||||
| PMID: | 9932161 | ||||||||||
| 4. | |||||||||||
| Journal: | J Clin Oncol. 1999 Feb;17(2):685-96. | ||||||||||
| Title: | Phase I and pharmacokinetic trial of oral irinotecan administered daily for 5 days every 3 weeks in patients with solid tumors. | ||||||||||
| Author: | Drengler, R L|Kuhn, J G|Schaaf, L J|Rodriguez, G I|Villalona-Calero, M A|Hammond, L A|Stephenson, J A Jr|Hodges, S|Kraynak, M A|Staton, B A|Elfring, G L|Locker, P K|Miller, L L|Von Hoff, D D|Rothenberg, M L | ||||||||||
| PMID: | 10080615 | ||||||||||
| 5. | |||||||||||
| Journal: | J Clin Oncol. 1999 Oct;17(10):3009-16. | ||||||||||
| Title: | Clinical and pharmacokinetic phase I study of multitargeted antifolate (LY231514) in combination with cisplatin. | ||||||||||
| Author: | Thodtmann, R|Depenbrock, H|Dumez, H|Blatter, J|Johnson, R D|van Oosterom, A|Hanauske, A R | ||||||||||
| PMID: | 10506594 | ||||||||||
| 6. | |||||||||||
| Journal: | Ann Oncol. 1999 Aug;10(8):915-21. | ||||||||||
| Title: | Concurrent irinotecan and 5-fluorouracil plus levo-folinic acid given every other week in the first-line management of advanced colorectal carcinoma: a phase I study of the Southern Italy Cooperative Oncology Group. | ||||||||||
| Author: | Comella, P|Casaretti, R|De Vita, F|Avallone, A|Orditura, M|Petrillo, A|Gravina, A|Faranda, A|Comis, S|Comella, G|Catalano, G | ||||||||||
| PMID: | 10509152 | ||||||||||
| 7. | |||||||||||
| Journal: | Curr Opin Investig Drugs. 2000 Sep;1(1):141-9. | ||||||||||
| Title: | ZD-9331 AstraZeneca. | ||||||||||
| Author: | Niculescu-Duvaz, I | ||||||||||
| PMID: | 11249590 | ||||||||||
| 8. | |||||||||||
| Journal: | J Clin Oncol. 2001 May 1;19(9):2433-8. | ||||||||||
| Title: | Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 phase I trial. | ||||||||||
| Author: | Freyer, G|Bossard, N|Romestaing, P|Mornex, F|Chapet, O|Trillet-Lenoir, V|Gerard, J P | ||||||||||
| PMID: | 11331322 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncology. 2002;63(1):42-7. | ||||||||||
| Title: | Multicenter phase I study of irinotecan plus raltitrexed in patients with 5-fluorouracil-refractory advanced colorectal cancer. | ||||||||||
| Author: | Aparicio, Jorge|de las Penas, Ramon|Vicent, Jose Maria|Garcera, Salvador|Llorca, Cristina|Maestu, Inmaculada|Yuste, Ana L|Farres, Jordi | ||||||||||
| PMID: | 12187070 | ||||||||||
| 10. | |||||||||||
| Journal: | Am J Clin Oncol. 2002 Oct;25(5):528-34. | ||||||||||
| Title: | Phase I clinical trial of irinotecan with oral capecitabine in patients with gastrointestinal and other solid malignancies. | ||||||||||
| Author: | Goel, Sanjay|Jhawer, Minaxi|Rajdev, Lakshmi|Hopkins, Una|Fehn, Karen|Baker, Cheryl|Chun, Hoo G|Makower, Della|Landau, Leon|Hoffman, Anthony|Wadler, Scott|Mani, Sridhar | ||||||||||
| PMID: | 12393999 | ||||||||||
| 11. | |||||||||||
| Journal: | Ann Oncol. 2002 Dec;13(12):1874-81. | ||||||||||
| Title: | Oxaliplatin plus irinotecan and leucovorin-modulated 5-fluorouracil triplet regimen every other week: a dose-finding study in patients with advanced gastrointestinal malignancies. | ||||||||||
| Author: | Comella, P|Casaretti, R|De Rosa, V|Avallone, A|Izzo, F|Fiore, F|Lapenta, L|Comella, G | ||||||||||
| PMID: | 12453855 | ||||||||||
| 12. | |||||||||||
| Journal: | Ann Oncol. 2003 Aug;14(8):1264-9. | ||||||||||
| Title: | A phase I/II study of oral uracil/tegafur (UFT), leucovorin and irinotecan in patients with advanced colorectal cancer. | ||||||||||
| Author: | Mackay, H J|Hill, M|Twelves, C|Glasspool, R|Price, T|Campbell, S|Massey, A|Macham, M A|Uzzel, M|Bailey, S M|Martin, C|Cunningham, D | ||||||||||
| PMID: | 12881390 | ||||||||||
| 13. | |||||||||||
| Journal: | J BUON. 2004 Jul-Sep;9(3):255-61. | ||||||||||
| Title: | Phase I study of postoperative radiotherapy with concomitant weekly irinotecan, 5- fluorouracil and folinic acid in locally advanced rectal cancer. | ||||||||||
| Author: | Ziras, N|Tsoutsou, P|Koliarakis, N|Magdalinos, N|Sarris, G|Potamianou, A|Paraskevaides, M|Synodinou, M|Chrysanthou, K|Karageorgis, P|Athanassiou, A E | ||||||||||
| PMID: | 17415823 | ||||||||||
| 14. | |||||||||||
| Journal: | J BUON. 2004 Oct-Dec;9(4):383-90. | ||||||||||
| Title: | The RACOX phase I study: radiation (RA), capecitabine (C) and oxaliplatin (OX) as adjuvant treatment of stage II and III rectal cancer. | ||||||||||
| Author: | Bountouroglou, N|Ziras, N|Sarris, G|Petrides, A|Potamianou, A|Synodinou, M|Karvounis, N|Angelides, A|Chrysanthou, K|Athanassiou, A E | ||||||||||
| PMID: | 17415843 | ||||||||||
| 15. | |||||||||||
| Journal: | Radiother Oncol. 2004 Feb;70(2):171-5. | ||||||||||
| Title: | Phase I study of UFT plus leucovorin with radiotherapy in patients with inextirpable non-rectal gastrointestinal cancer. | ||||||||||
| Author: | Bystrom, P|Frodin, J-E|Berglund, A|Wilking, N|Glimelius, B | ||||||||||
| PMID: | 15028404 | ||||||||||
| 16. | |||||||||||
| Journal: | Anticancer Drugs. 2004 Mar;15(3):219-27. | ||||||||||
| Title: | Phase I trial of sequential raltitrexed followed by bolus 5-fluorouracil in patients with advanced colorectal cancer. | ||||||||||
| Author: | Schwartz, Gary K|Bertino, Joseph|Kemeny, Nancy|Saltz, Leonard|Kelsen, David K|Tong, William|Welch, Mary|Endres, Sandra|Dimery, Isaiah | ||||||||||
| PMID: | 15014354 | ||||||||||
| 17. | |||||||||||
| Journal: | Eur J Cancer. 2005 Jan;41(1):93-7. | ||||||||||
| Title: | Phase I study of concomitant chemoradiation with raltitrexed in locally advanced head and neck cancer. | ||||||||||
| Author: | Planting, A|de Jong, M|Jansen, P|Kerrebijn, J|Smith, M|Verweij, J | ||||||||||
| PMID: | 15719490 | ||||||||||
| 18. | |||||||||||
| Journal: | Eur J Cancer. 2005 Jul;41(10):1431-8. | ||||||||||
| Title: | Weekly 24 h infusion of aviscumine (rViscumin): a phase I study in patients with solid tumours. | ||||||||||
| Author: | Schoffski, P|Breidenbach, I|Krauter, J|Bolte, O|Stadler, M|Ganser, A|Wilhelm-Ogunbiyi, K|Lentzen, H | ||||||||||
| PMID: | 15913988 | ||||||||||
| 19. | |||||||||||
| Journal: | J Clin Oncol. 2005 Dec 20;23(36):9120-9. | ||||||||||
| Title: | Phase I dose-finding study of weekly single-agent patupilone in patients with advanced solid tumors. | ||||||||||
| Author: | Rubin, Eric H|Rothermel, John|Tesfaye, Fisseha|Chen, Tianling|Hubert, Martine|Ho, Yu-Yun|Hsu, Chyi-Hung|Oza, Amit M | ||||||||||
| PMID: | 16301595 | ||||||||||
| 20. | |||||||||||
| Journal: | J Clin Oncol. 2006 Feb 1;24(4):656-62. | ||||||||||
| Title: | Increased toxicity with gefitinib, capecitabine, and radiation therapy in pancreatic and rectal cancer: phase I trial results. | ||||||||||
| Author: | Czito, Brian G|Willett, Christopher G|Bendell, Johanna C|Morse, Michael A|Tyler, Douglas S|Fernando, Nishan H|Mantyh, Christopher R|Blobe, Gerard C|Honeycutt, Wanda|Yu, Daohai|Clary, Bryan M|Pappas, Theodore N|Ludwig, Kirk A|Hurwitz, Herbert I | ||||||||||
| PMID: | 16446337 | ||||||||||
| 21. | |||||||||||
| Journal: | Ann Oncol. 2007 Apr;18(4):730-7. | ||||||||||
| Title: | Gefitinib and irinotecan in patients with fluoropyrimidine-refractory, irinotecan-naive advanced colorectal cancer: a phase I-II study. | ||||||||||
| Author: | Chau, I|Cunningham, D|Hickish, T|Massey, A|Higgins, L|Osborne, R|Botwood, N|Swaisland, A | ||||||||||
| PMID: | 17237473 | ||||||||||
| 22. | |||||||||||
| Journal: | J Clin Oncol. 2008 Apr 1;26(10):1603-10. | ||||||||||
| Title: | Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors. | ||||||||||
| Author: | Tabernero, Josep|Rojo, Federico|Calvo, Emiliano|Burris, Howard|Judson, Ian|Hazell, Katharine|Martinelli, Erika|Ramon y Cajal, Santiago|Jones, Suzanne|Vidal, Laura|Shand, Nicholas|Macarulla, Teresa|Ramos, Francisco Javier|Dimitrijevic, Sasa|Zoellner, Ulrik | ||||||||||
| PMID: | 18332469 | ||||||||||
| 23. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2008 Oct;35(10):1697-701. | ||||||||||
| Title: | [Phase I study of CPT-11 and continuous 5-FU / l-leucovorin combination therapy(modified AIO regimen)in patients with metastatic colorectal cancer]. | ||||||||||
| Author: | Nakamura, Toshio|Kurachi, Kiyotaka|Fukazawa, Atsuko|Hayashi, Tadataka|Nakamura, Koichi|Nakajima, Akihito|Suzuki, Shohachi|Konno, Hiroyuki | ||||||||||
| PMID: | 18931571 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2009 Sep;64(4):665-72. | ||||||||||
| Title: | Vandetanib with FOLFIRI in patients with advanced colorectal adenocarcinoma: results from an open-label, multicentre Phase I study. | ||||||||||
| Author: | Saunders, Mark P|Wilson, Richard|Peeters, Marc|Smith, Robert|Godwood, Alex|Oliver, Stuart|Van Cutsem, Eric | ||||||||||
| PMID: | 19184020 | ||||||||||
| 25. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2010 Dec;9(5):297-304. | ||||||||||
| Title: | Phase I trial of oxaliplatin, infusional 5-fluorouracil, and leucovorin (FOLFOX4) with erlotinib and bevacizumab in colorectal cancer. | ||||||||||
| Author: | Messersmith, Wells A|Jimeno, Antonio|Jacene, Heather|Zhao, Ming|Kulesza, Piotr|Laheru, Daniel A|Kahn, Yasmin|Spira, Alexander|Dancey, Janet|Iacobuzio-Donahue, Christine|Donehower, Ross C|Carducci, Michael|Rudek, Michelle A|Hidalgo, Manuel | ||||||||||
| PMID: | 21208844 | ||||||||||
| 26. | |||||||||||
| Journal: | Clin Cancer Res. 2010 Jul 15;16(14):3786-94. | ||||||||||
| Title: | A phase I, pharmacokinetic, and pharmacodynamic study of two schedules of vorinostat in combination with 5-fluorouracil and leucovorin in patients with refractory solid tumors. | ||||||||||
| Author: | Fakih, Marwan G|Fetterly, Gerald|Egorin, Merrill J|Muindi, Josephia R|Espinoza-Delgado, Igor|Zwiebel, James A|Litwin, Alan|Holleran, Julianne L|Wang, Kangsheng|Diasio, Robert B | ||||||||||
| PMID: | 20463088 | ||||||||||
| 27. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2010 Oct;66(5):927-33. | ||||||||||
| Title: | Plasma and cerebrospinal fluid pharmacokinetics of topotecan in a phase I trial of topotecan, tamoxifen, and carboplatin, in the treatment of recurrent or refractory brain or spinal cord tumors. | ||||||||||
| Author: | Morgan, Robert J|Synold, Timothy|Mamelak, Adam|Lim, Dean|Al-Kadhimi, Zaid|Twardowski, Przemyslaw|Leong, Lucille|Chow, Warren|Margolin, Kim|Shibata, Stephen|Somlo, George|Yen, Yun|Frankel, Paul|Doroshow, James H | ||||||||||
| PMID: | 20107803 | ||||||||||
| 28. | |||||||||||
| Journal: | Phytomedicine. 2010 Mar;17(3-4):161-9. | ||||||||||
| Title: | Phase I study of the botanical formulation PHY906 with capecitabine in advanced pancreatic and other gastrointestinal malignancies. | ||||||||||
| Author: | Saif, M Wasif|Lansigan, F|Ruta, S|Lamb, L|Mezes, M|Elligers, K|Grant, N|Jiang, Z-L|Liu, S H|Cheng, Y-C | ||||||||||
| PMID: | 20092990 | ||||||||||
| 29. | |||||||||||
| Journal: | Onkologie. 2010;33(3):89-93. | ||||||||||
| Title: | Gefitinib in combination with capecitabine as second-line therapy in patients with advanced colorectal cancer (aCRC): a phase I/II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). | ||||||||||
| Author: | Trarbach, Tanja|Reinacher-Schick, Anke|Hegewisch-Becker, Susanne|Vanhoefer, Udo|Frieling, Thomas|Lehnert, Lasse|Schmiegel, Wolff|Graeven, Ullrich | ||||||||||
| PMID: | 20215798 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2011 Jul;68(1):247-53. | ||||||||||
| Title: | Phase I clinical trial of hepatic arterial infusion of paclitaxel in patients with advanced cancer and dominant liver involvement. | ||||||||||
| Author: | Tsimberidou, Apostolia M|Letourneau, Katherine|Fu, Siqing|Hong, David|Naing, Aung|Wheler, Jennifer|Uehara, Cynthia|McRae, Stephen E|Wen, Sijin|Kurzrock, Razelle | ||||||||||
| PMID: | 20941597 | ||||||||||
| 31. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Nov 15;17(22):7156-63. | ||||||||||
| Title: | Biologic and clinical activity of tivozanib (AV-951, KRN-951), a selective inhibitor of VEGF receptor-1, -2, and -3 tyrosine kinases, in a 4-week-on, 2-week-off schedule in patients with advanced solid tumors. | ||||||||||
| Author: | Eskens, Ferry A L M|de Jonge, Maja J A|Bhargava, Pankaj|Isoe, Toshiyuki|Cotreau, Monette M|Esteves, Brooke|Hayashi, Kunihiko|Burger, Herman|Thomeer, Maarten|van Doorn, Leni|Verweij, Jaap | ||||||||||
| PMID: | 21976547 | ||||||||||
| 32. | |||||||||||
| Journal: | Br J Cancer. 2011 Nov 22;105(11):1646-53. | ||||||||||
| Title: | Clinical activity of patupilone in patients with pretreated advanced/metastatic colon cancer: results of a phase I dose escalation trial. | ||||||||||
| Author: | Melichar, B|Casado, E|Bridgewater, J|Bennouna, J|Campone, M|Vitek, P|Delord, J-P|Cerman, J Jr|Salazar, R|Dvorak, J|Sguotti, C|Urban, P|Viraswami-Appanna, K|Tan, E|Tabernero, J | ||||||||||
| PMID: | 22027708 | ||||||||||
| 33. | |||||||||||
| Journal: | Invest New Drugs. 2012 Aug;30(4):1511-8. | ||||||||||
| Title: | Phase I results from a two-part Phase I/II study of cediranib in combination with mFOLFOX6 in Japanese patients with metastatic colorectal cancer. | ||||||||||
| Author: | Satoh, Taroh|Yamaguchi, Kensei|Boku, Narikazu|Okamoto, Wataru|Shimamura, Tomotaka|Yamazaki, Kentaro|Shi, Xiaojin|Mishima, Hideyuki | ||||||||||
| PMID: | 21611734 | ||||||||||
| 34. | |||||||||||
| Journal: | Invest New Drugs. 2012 Aug;30(4):1591-6. | ||||||||||
| Title: | A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy. | ||||||||||
| Author: | Ramanathan, Ramesh K|Stephenson, Joe J|Weiss, Glen J|Pestano, Linda A|Lowe, Ann|Hiscox, Alton|Leos, Rafael A|Martin, Julie C|Kirkpatrick, Lynn|Richards, Donald A | ||||||||||
| PMID: | 21863237 | ||||||||||
| 35. | |||||||||||
| Journal: | Cancer. 2012 Dec 15;118(24):6144-51. | ||||||||||
| Title: | Safety, pharmacokinetics, and activity of EZN-2208, a novel conjugate of polyethylene glycol and SN38, in patients with advanced malignancies. | ||||||||||
| Author: | Kurzrock, Razelle|Goel, Sanjay|Wheler, Jennifer|Hong, David|Fu, Siqing|Rezai, Keyvan|Morgan-Linnell, Sonia K|Urien, Saik|Mani, Sridhar|Chaudhary, Imran|Ghalib, Mohammed H|Buchbinder, Aby|Lokiec, Francois|Mulcahy, Mary | ||||||||||
| PMID: | 22674635 | ||||||||||
| 36. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2013 Sep;72(3):643-52. | ||||||||||
| Title: | Phase 1 pharmacokinetic study of MK-0646 (dalotuzumab), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in combination with cetuximab and irinotecan in Japanese patients with advanced colorectal cancer. | ||||||||||
| Author: | Doi, Toshihiko|Muro, Kei|Yoshino, Takayuki|Fuse, Nozomu|Ura, Takashi|Takahari, Daisuke|Feng, Hwa-Ping|Shimamoto, Takashi|Noguchi, Kazuo|Ohtsu, Atsushi | ||||||||||
| PMID: | 23921573 | ||||||||||
| 37. | |||||||||||
| Journal: | Br J Cancer. 2013 Oct 1;109(7):1725-34. | ||||||||||
| Title: | A phase 1 trial of imatinib, bevacizumab, and metronomic cyclophosphamide in advanced colorectal cancer. | ||||||||||
| Author: | Kelley, R K|Hwang, J|Magbanua, M J M|Watt, L|Beumer, J H|Christner, S M|Baruchel, S|Wu, B|Fong, L|Yeh, B M|Moore, A P|Ko, A H|Korn, W M|Rajpal, S|Park, J W|Tempero, M A|Venook, A P|Bergsland, E K | ||||||||||
| PMID: | 24022191 | ||||||||||
| 38. | |||||||||||
| Journal: | Invest New Drugs. 2014 Feb;32(1):113-22. | ||||||||||
| Title: | Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients. | ||||||||||
| Author: | Rubinson, Douglas A|Hochster, Howard S|Ryan, David P|Wolpin, Brian M|McCleary, Nadine Jackson|Abrams, Thomas A|Chan, Jennifer A|Iqbal, Syma|Lenz, Heinz J|Lim, Dean|Rose, Jeffrey|Bekaii-Saab, Tanios|Chen, Helen X|Fuchs, Charles S|Ng, Kimmie | ||||||||||
| PMID: | 23568716 | ||||||||||
| 39. | |||||||||||
| Journal: | Acta Radiol. 2014 Sep;55(7):793-801. | ||||||||||
| Title: | Negative-balance isolated pelvic perfusion in patients with incurable symptomatic rectal cancer: results and drug dose correlation to adverse events. | ||||||||||
| Author: | Murata, Satoru|Onozawa, Shiro|Kim, Chol|Tajima, Hiroyuki|Kimata, Ryoji|Uchida, Eiji|Kumita, Shin-Ichiro | ||||||||||
| PMID: | 24097815 | ||||||||||
| 40. | |||||||||||
| Journal: | J Gastrointest Cancer. 2014 Dec;45(4):460-5. | ||||||||||
| Title: | Neutropenia and relative dose intensity on adjuvant FOLFOX chemotherapy are not associated with survival for resected colon cancer. | ||||||||||
| Author: | Smoragiewicz, Martin|Javaheri, Khodadad R|Yin, Yaling|Gill, Sharlene | ||||||||||
| PMID: | 25012517 | ||||||||||
| 41. | |||||||||||
| Journal: | Int J Clin Oncol. 2015 Apr;20(2):338-44. | ||||||||||
| Title: | A phase I trial of preoperative S-1 in combination with oxaliplatin and pelvic radiation for lower rectal cancer with T4 and lateral pelvic lymph node metastasis. | ||||||||||
| Author: | Ohue, Masayuki|Hamaguchi, Tetsuya|Ito, Yoshinori|Sakai, Daisuke|Noura, Shingo|Kinugasa, Yusuke|Fujita, Shin|Shimada, Yasuhiro|Saito, Norio|Moriya, Yoshihiro | ||||||||||
| PMID: | 24839048 | ||||||||||
| 42. | |||||||||||
| Journal: | Invest New Drugs. 2015 Oct;33(5):1086-92. | ||||||||||
| Title: | Phase 1 study of APTO-253 HCl, an inducer of KLF4, in patients with advanced or metastatic solid tumors. | ||||||||||
| Author: | Cercek, Andrea|Wheler, Jennifer|Murray, Peter E|Zhou, Shawn|Saltz, Leonard | ||||||||||
| PMID: | 26268924 | ||||||||||
| 43. | |||||||||||
| Journal: | Invest New Drugs. 2015 Oct;33(5):1068-77. | ||||||||||
| Title: | Phase I study of TAS-102 and irinotecan combination therapy in Japanese patients with advanced colorectal cancer. | ||||||||||
| Author: | Doi, Toshihiko|Yoshino, Takayuki|Fuse, Nozomu|Boku, Narikazu|Yamazaki, Kentaro|Koizumi, Wasaburo|Shimada, Ken|Takinishi, Yasutaka|Ohtsu, Atsushi | ||||||||||
| PMID: | 26163340 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Res Treat. 2015 Oct;47(4):607-15. | ||||||||||
| Title: | Phase I Study of OPB-31121, an Oral STAT3 Inhibitor, in Patients with Advanced Solid Tumors. | ||||||||||
| Author: | Oh, Do-Youn|Lee, Se-Hoon|Han, Sae-Won|Kim, Mi-Jung|Kim, Tae-Min|Kim, Tae-You|Heo, Dae Seog|Yuasa, Miyuki|Yanagihara, Yasuo|Bang, Yung-Jue | ||||||||||
| PMID: | 25715763 | ||||||||||
| 45. | |||||||||||
| Journal: | J Clin Pharmacol. 2016 Aug;56(8):966-73. | ||||||||||
| Title: | Phase 1 Study of ABT-751 in Combination With CAPIRI (Capecitabine and Irinotecan) and Bevacizumab in Patients With Advanced Colorectal Cancer. | ||||||||||
| Author: | Rudek, Michelle A|Dasari, Arvind|Laheru, Daniel|He, Ping|Jin, Runyan|Walker, Rosalind|Taylor, Gretchen E|Jimeno, Antonio|Donehower, Ross C|Hidalgo, Manuel|Messersmith, Wells A|Purcell, W Thomas | ||||||||||
| PMID: | 26632033 | ||||||||||
| 46. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Jul 1;22(13):3209-17. | ||||||||||
| Title: | A Phase I Clinical, Pharmacokinetic, and Pharmacodynamic Study of Weekly or Every Three Week Ixabepilone and Daily Sunitinib in Patients with Advanced Solid Tumors. | ||||||||||
| Author: | Montero, Alberto J|Kwon, Deukwoo|Flores, Aurea|Kovacs, Krisztina|Trent, Jonathan C|Benedetto, Pasquale|Rocha-Lima, Caio|Merchan, Jaime R | ||||||||||
| PMID: | 26864210 | ||||||||||
| 47. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2016 May;77(5):1097-102. | ||||||||||
| Title: | Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer. | ||||||||||
| Author: | Said, Rabih|Kakadiaris, Eugenia|Piha-Paul, Sarina|Fu, Siqing|Falchook, Gerald|Janku, Filip|Wheler, Jennifer J|Zinner, Ralph|Hong, David S|Kurzrock, Razelle|Tsimberidou, Apostolia M | ||||||||||
| PMID: | 27085994 | ||||||||||
| 48. | |||||||||||
| Journal: | Clin Cancer Res. 2017 Aug 1;23(15):4146-4154. | ||||||||||
| Title: | Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer. | ||||||||||
| Author: | Parseghian, Christine M|Parikh, Nila U|Wu, Ji Yuan|Jiang, Zhi-Qin|Henderson, Laura|Tian, Feng|Pastor, Brice|Ychou, Marc|Raghav, Kanwal|Dasari, Arvind|Fogelman, David R|Katsiampoura, Anastasia D|Menter, David G|Wolff, Robert A|Eng, Cathy|Overman, Michael J | ||||||||||
| PMID: | 28280091 | ||||||||||
| 49. | |||||||||||
| Journal: | Int J Radiat Oncol Biol Phys. 2017 Jul 15;98(4):908-917. | ||||||||||
| Title: | Endorectal Brachytherapy Boost After External Beam Radiation Therapy in Elderly or Medically Inoperable Patients With Rectal Cancer: Primary Outcomes of the Phase 1 HERBERT Study. | ||||||||||
| Author: | Rijkmans, Eva C|Cats, Annemieke|Nout, Remi A|van den Bongard, Desiree H J G|Ketelaars, Martijn|Buijsen, Jeroen|Rozema, Tom|Franssen, Jan-Huib|Velema, Laura A|van Triest, Baukelien|Marijnen, Corrie A M | ||||||||||
| PMID: | 28366579 | ||||||||||
| 50. | |||||||||||
| Journal: | JCI Insight. 2017 Apr 20;2(8). pii: 90380. | ||||||||||
| Title: | First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients. | ||||||||||
| Author: | Subbiah, Vivek|Khawaja, Muhammad Rizwan|Hong, David S|Amini, Behrang|Yungfang, Jiang|Liu, Hui|Johnson, Adrienne|Schrock, Alexa B|Ali, Siraj M|Sun, James X|Fabrizio, David|Piha-Paul, Sarina|Fu, Siqing|Tsimberidou, Apostolia M|Naing, Aung|Janku, Filip|Karp, | ||||||||||
| PMID: | 28422758 | ||||||||||
| 51. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2017 May 23;39(5):380-383. | ||||||||||
| Title: | [Safety and efficacy of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) in Chinese patients with advanced colorectal cancer]. | ||||||||||
| Author: | Song, Y|Li, W W|Huang, J | ||||||||||
| PMID: | 28535657 | ||||||||||
| 52. | |||||||||||
| Journal: | Radiother Oncol. 2017 Dec 19. pii: S0167-8140(17)32749-4. | ||||||||||
| Title: | Genotype-driven phase I study of weekly irinotecan in combination with capecitabine-based neoadjuvant chemoradiation for locally advanced rectal cancer. | ||||||||||
| Author: | Zhu, Ji|Li, Xinxiang|Shen, Yunzhu|Guan, Yun|Gu, Weilie|Lian, Peng|Sheng, Weiqi|Cai, Sanjun|Zhang, Zhen | ||||||||||
| PMID: | 29273261 | ||||||||||
| 53. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2018 Jun;17(2):156-163. | ||||||||||
| Title: | Survival Impact of CAPOX Versus FOLFOX in the Adjuvant Treatment of Stage III Colon Cancer. | ||||||||||
| Author: | Loree, Jonathan M|Sha, Aaron|Soleimani, Maryam|Kennecke, Hagen F|Ho, Maria Y|Cheung, Winson Y|Mulder, Karen E|Abadi, Shirin|Spratlin, Jennifer L|Gill, Sharlene | ||||||||||
| PMID: | 29486916 | ||||||||||
| 54. | |||||||||||
| Journal: | Invest New Drugs. 2018 Sep 6. pii: 10.1007/s10637-018-0663-0. | ||||||||||
| Title: | Phase I study combining the aurora kinase a inhibitor alisertib with mFOLFOX in gastrointestinal cancer. | ||||||||||
| Author: | Goff, Laura W|Azad, Nilo|Stein, Stacey|Whisenant, Jennifer G|Koyama, Tatsuki|Vaishampayan, Ulka|Hochster, Howard|Connolly, Roisin|Weise, Amy|LoRusso, Patricia M|Salaria, Safia N|El-Rifai, Wael|Berlin, Jordan D | ||||||||||
| PMID: | 30191522 | ||||||||||