Primary Site >> Liver Cancer

Gene >> CD69

Journal: Scand J Clin Lab Invest. 2001;61(5):363-70.
Title: CD4+ T-lymphocytopenia and systemic immune activation in patients with primary and secondary liver tumours.
Author: Melichar, B|Touskova, M|Solichova, D|Kralickova, P|Kopecky, G
PMID: 11569483
Journal: J Immunol. 2003 Feb 1;170(3):1183-90.
Title: Tumor eradication by hepatitis B virus X antigen-specific CD8+ T cells in xenografted nude mice.
Author: Chun, Eunyoung|Lee, Jihyun|Cheong, Hong Seok|Lee, Ki-Young
PMID: 12538674
Journal: J Immunol. 2003 Aug 15;171(4):1775-9.
Title: NKT cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine NKT cells.
Author: Kenna, Tony|Golden-Mason, Lucy|Porcelli, Steven A|Koezuka, Yasuhiko|Hegarty, John E|O'Farrelly, Cliona|Doherty, Derek G
PMID: 12902477
Journal: Clin Immunol. 2005 Feb;114(2):174-82.
Title: Chemokine receptors support infiltration of lymphocyte subpopulations in human hepatocellular carcinoma.
Author: Liu, Yuqing|Poon, Ronnie T|Hughes, Jeremy|Feng, Xiaoqin|Yu, Wan Ching|Fan, Sheung Tat
PMID: 15639651
Journal: Cancer Immunol Immunother. 2006 Dec;55(12):1459-69.
Title: Increased liver temperature efficiently augments human cellular immune response: T-cell activation and possible monocyte translocation.
Author: Kida, Yohei|Tsuji-Kawahara, Sachiyo|Ostapenko, Valentina|Kinoshita, Saori|Kajiwara, Eiji|Kawabata, Hiroyuki|Yuasa, Takae|Nishide, Iwao|Yukawa, Susumu|Ichinose, Masakazu|Miyazawa, Masaaki
PMID: 16491400
Journal: Transplantation. 2006 Dec 27;82(12):1712-9.
Title: Adoptive transfer of TRAIL-expressing natural killer cells prevents recurrence of hepatocellular carcinoma after partial hepatectomy.
Author: Ohira, Masahiro|Ohdan, Hideki|Mitsuta, Hiroshi|Ishiyama, Kohei|Tanaka, Yuka|Igarashi, Yuka|Asahara, Toshimasa
PMID: 17198265
Journal: J Virol. 2007 Sep;81(17):9502-11.
Title: Local expression of secondary lymphoid tissue chemokine delivered by adeno-associated virus within the tumor bed stimulates strong anti-liver tumor immunity.
Author: Liang, Chun-min|Zhong, Cui-ping|Sun, Rui-xia|Liu, Bin-bin|Huang, Cheng|Qin, Jie|Zhou, Shuang|Shan, Junling|Liu, Yin-kun|Ye, Sheng-long
PMID: 17567706
Journal: Hepatogastroenterology. 2007 Jul-Aug;54(77):1529-33.
Title: Phenotypic analysis of tumor-infiltrating lymphocytes in hepatocellular carcinoma.
Author: Chen, Chien-Hung|Lee, Hsuan-Shu|Huang, Guan-Tarn|Yang, Pei-Ming|Yu, Wei-Yuan|Cheng, Kuang-Chun|Lee, Po-Huang|Jeng, Yung-Ming|Chen, Ding-Shinn|Sheu, Jin-Chuan
PMID: 17708291
Journal: Hepatology. 2007 Jun;45(6):1400-12.
Title: Impairment of liver regeneration correlates with activated hepatic NKT cells in HBV transgenic mice.
Author: Dong, Zhongjun|Zhang, Jianhong|Sun, Rui|Wei, Haiming|Tian, Zhigang
PMID: 17523147
Journal: Lab Invest. 2007 Jun;87(6):582-90.
Title: Hepatocellular carcinoma cell supernatants increase expansion and function of CD4(+)CD25(+) regulatory T cells.
Author: Cao, Mengde|Cabrera, Roniel|Xu, Yiling|Firpi, Roberto|Zhu, Haizhen|Liu, Chen|Nelson, David R
PMID: 17372588
Journal: Invest Clin. 2008 Sep;49(3):353-67.
Title: [Impaired activation and costimulation of T CD4+ lymphocytes during chronic hepatitis C infection].
Author: Barboza, Luisa|Martens, Maria Luisa|Salmen, Siham|Peterson, Darrell L|Montes, Henry|Berrueta, Lisbeth
PMID: 18846776
Journal: Liver Int. 2010 Oct;30(9):1379-86.
Title: Increased PD-1 and decreased CD28 expression in chronic hepatitis B patients with advanced hepatocellular carcinoma.
Author: Hsu, Ping-Ning|Yang, Tsuey-Ching|Kao, Jung-Ta|Cheng, Ken-Sheng|Lee, Yi-Ju|Wang, Yuan-Min|Hsieh, Chin-Tung|Lin, Cheng-Wen|Wu, Yi-Ying
PMID: 20738778
Journal: J Gastroenterol Hepatol. 2011 Oct;26(10):1519-26.
Title: Increased CD4(+) CD69(+) CD25(-) T cells in patients with hepatocellular carcinoma are associated with tumor progression.
Author: Zhu, Jiankang|Feng, Alei|Sun, Jintang|Jiang, Zhenzhong|Zhang, Guangyong|Wang, Kexin|Hu, Sanyuan|Qu, Xun
PMID: 21557772
Journal: PLoS One. 2011;6(9):e24671.
Title: Selective recruitment of regulatory T cell through CCR6-CCL20 in hepatocellular carcinoma fosters tumor progression and predicts poor prognosis.
Author: Chen, Kang-Jie|Lin, Sheng-Zhang|Zhou, Lin|Xie, Hai-Yang|Zhou, Wu-Hua|Taki-Eldin, Ahmed|Zheng, Shu-Sen
PMID: 21935436
Journal: J Gastroenterol Hepatol. 2011 Oct;26(10):1469-70.
Title: Are non-traditional CD4(+) CD69(+) CD25(-) regulatory T cells involved in disease progression of human hepatocellular carcinoma?
Author: Xu, Dongping|Wang, Fu-Sheng
PMID: 21950742
Journal: Onco Targets Ther. 2012;5:103-9.
Title: Treatment with transcatheter arterial chemoembolization induces an increase of the L-selectin(low) CXCR3+ CD8+ T cell subset in patients with hepatocellular carcinoma.
Author: Zheng, Jiasheng|Sun, Bin|Liu, Daojie|Yan, Li|Wang, Yanjun
PMID: 22719212
Journal: Cell Transplant. 2012;21(7):1397-406.
Title: Clinical-scale isolation of interleukin-2-stimulated liver natural killer cells for treatment of liver transplantation with hepatocellular carcinoma.
Author: Ohira, Masahiro|Nishida, Seigo|Tryphonopoulos, Panagiotis|Tekin, Akin|Selvaggi, Gennaro|Moon, Jang|Levi, David|Ricordi, Camillo|Ishiyama, Kohei|Tanaka, Yuka|Ohdan, Hideki|Tzakis, Andreas G
PMID: 22469170
Journal: J Immunol. 2012 Feb 1;188(3):1117-24.
Title: Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-associated macrophages.
Author: Zhao, Qiyi|Kuang, Dong-Ming|Wu, Yan|Xiao, Xiao|Li, Xue-Feng|Li, Tuan-Jie|Zheng, Limin
PMID: 22184722
Journal: J Biol Chem. 2012 May 4;287(19):15874-85.
Title: Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro.
Author: Lv, Li-Hong|Wan, Yun-Le|Lin, Yan|Zhang, Wei|Yang, Mei|Li, Guo-Lin|Lin, Hao-Ming|Shang, Chang-Zhen|Chen, Ya-Jin|Min, Jun
PMID: 22396543
Journal: PLoS One. 2013;8(2):e55945.
Title: Suppression of natural killer cells by sorafenib contributes to prometastatic effects in hepatocellular carcinoma.
Author: Zhang, Qiang-Bo|Sun, Hui-Chuan|Zhang, Ke-Zhi|Jia, Qing-An|Bu, Yang|Wang, Miao|Chai, Zong-Tao|Zhang, Quan-Bao|Wang, Wen-Quan|Kong, Ling-Qun|Zhu, Xiao-dong|Lu, Lu|Wu, Wei-Zhong|Wang, Lu|Tang, Zhao-You
PMID: 23409093
Journal: J Transl Med. 2013 Mar 20;11:70.
Title: Shedding LIGHT (TNFSF14) on the tumor microenvironment of colorectal cancer liver metastases.
Author: Qin, Jian Zhong|Upadhyay, Vivek|Prabhakar, Bellur|Maker, Ajay V
PMID: 23514280
Journal: Int J Cancer. 2013 Dec 15;133(12):2895-902.
Title: Serum interferon gamma level predicts recurrence in hepatocellular carcinoma patients after curative treatments.
Author: Lee, I-Cheng|Huang, Yi-Hsiang|Chau, Gar-Yang|Huo, Teh-Ia|Su, Chien-Wei|Wu, Jaw-Ching|Lin, Han-Chieh
PMID: 23749461
Journal: J Mol Med (Berl). 2014 May;92(5):539-50.
Title: Human hepatocellular carcinoma-infiltrating CD4(+)CD69(+)Foxp3(-) regulatory T cell suppresses T cell response via membrane-bound TGF-beta1.
Author: Han, Yanmei|Yang, Yuan|Chen, Zhubo|Jiang, Zhengping|Gu, Yan|Liu, Yanfang|Xu, Sheng|Lin, Chuan|Pan, Zeya|Zhou, Weiping|Cao, Xuetao
PMID: 24668348
Journal: Oncoimmunology. 2015 Apr 1;4(7):e1016706.
Title: Restoration of natural killer activity in hepatocellular carcinoma by treatment with antibody against granulin-epithelin precursor.
Author: Cheung, Phyllis Fy|Yip, Chi Wai|Ng, Linda Wc|Wong, Chun Kwok|Cheung, Tan To|Lo, Chung Mau|Fan, Sheung Tat|Cheung, Siu Tim
PMID: 26140244
Journal: Cancer Discov. 2016 Oct;6(10):1182-1195.
Title: Polarization of Tissue-Resident TFH-Like Cells in Human Hepatoma Bridges Innate Monocyte Inflammation and M2b Macrophage Polarization.
Author: Chen, Min-Min|Xiao, Xiao|Lao, Xiang-Ming|Wei, Yuan|Liu, Rui-Xian|Zeng, Qiu-Hui|Wang, Jun-Cheng|Ouyang, Fang-Zhu|Chen, Dong-Ping|Chan, Ka-Wo|Shi, Dai-Chao|Zheng, Limin|Kuang, Dong-Ming
PMID: 27531854
Journal: Am J Physiol Gastrointest Liver Physiol. 2016 Oct 1;311(4):G699-G712.
Title: Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model.
Author: Velazquez, Kandy T|Enos, Reilly T|Carson, Meredith S|Cranford, Taryn L|Bader, Jackie E|Chatzistamou, Ioulia|Singh, Udai P|Nagarkatti, Prakash S|Nagarkatti, Mitzi|Davis, J Mark|Carson, James A|Murphy, E Angela
PMID: 27609769
Journal: Inflammation. 2016 Oct;39(5):1729-36.
Title: Parallel Profiles of Inflammatory and Effector Memory T Cells in Visceral Fat and Liver of Obesity-Associated Cancer Patients.
Author: Conroy, Melissa J|Galvin, Karen C|Doyle, Suzanne L|Kavanagh, Maria E|Mongan, Ann-Marie|Cannon, Aoife|Moore, Gillian Y|Reynolds, John V|Lysaght, Joanne
PMID: 27423204
Journal: Virol J. 2016 Apr 18;13:67.
Title: Increased CD56(bright) NK cells in HIV-HCV co-infection and HCV mono-infection are associated with distinctive alterations of their phenotype.
Author: Bhardwaj, Suvercha|Ahmad, Fareed|Wedemeyer, Heiner|Cornberg, Marcus|Schulze Zur Wiesch, Julian|van Lunzen, Jan|Sarin, Shiv K|Schmidt, Reinhold E|Meyer-Olson, Dirk
PMID: 27091211
Journal: Mol Med Rep. 2016 Apr;13(4):3197-205.
Title: Improvement of the cytotoxic T lymphocyte response against hepatocellular carcinoma by transduction of cancer cells with an adeno-associated virus carrying the interferon-gamma gene.
Author: Zhou, Jun|Ma, Ping|Li, Jun|Cui, Xiaonan|Song, Wei
PMID: 26936017
Journal: Integr Cancer Ther. 2017 Sep;16(3):329-338.
Title: Fuzheng Qingjie Granules Inhibit Growth of Hepatoma Cells via Inducing Mitochondria-Mediated Apoptosis and Enhancing Immune Function.
Author: Chen, Xuzheng|Cao, Zhiyun|Zhang, Youquan|Li, Jinnong|Wang, Suqing|Du, Jian|Liao, Lianming
PMID: 27335087
Journal: Cancer Immunol Res. 2017 Jun;5(6):493-502.
Title: Tumor-Derived alpha-Fetoprotein Directly Drives Human Natural Killer-Cell Activation and Subsequent Cell Death.
Author: Vujanovic, Lazar|Stahl, Elizabeth C|Pardee, Angela D|Geller, David A|Tsung, Allan|Watkins, Simon C|Gibson, Gregory A|Storkus, Walter J|Butterfield, Lisa H
PMID: 28468916
Journal: Innate Immun. 2017 Jul;23(5):459-467.
Title: Decrease of CD69 levels on TCR Valpha7.2(+)CD4(+) innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients.
Author: Yong, Yean K|Tan, Hong Y|Saeidi, Alireza|Rosmawati, Mohamed|Atiya, Nadia|Ansari, Abdul W|Rajarajeswaran, Jayakumar|Vadivelu, Jamuna|Velu, Vijayakumar|Larsson, Marie|Shankar, Esaki M
PMID: 28606013
Journal: Folia Parasitol (Praha). 2017 Aug 25;64.
Title: Echinococcus multilocularis vesicular fluid inhibits activation and proliferation of natural killer cells.
Author: Bellanger, Anne-Pauline|Mougey, Valentine|Pallandre, Jean-Rene|Gbaguidi-Haore, Houssein|Godet, Yann|Millon, Laurence
PMID: 28906255
Journal: Cell Death Dis. 2018 Feb 7;9(2):159.
Title: 14-3-3zeta delivered by hepatocellular carcinoma-derived exosomes impaired anti-tumor function of tumor-infiltrating T lymphocytes.
Author: Wang, Xiaochen|Shen, Haiyuan|Zhangyuan, Guangyan|Huang, Ruyi|Zhang, Wenjie|He, Qifeng|Jin, Kangpeng|Zhuo, Han|Zhang, Zechuan|Wang, Jincheng|Sun, Beicheng|Lu, Xiaojie
PMID: 29415983
Journal: J Med Genet. 2018 Apr 17. pii: jmedgenet-2018-105267.
Title: Genetic and phenotypic difference in CD8(+) T cell exhaustion between chronic hepatitis B infection and hepatocellular carcinoma.
Author: Wang, Xiaochen|He, Qifeng|Shen, Haiyuan|Lu, Xiao-Jie|Sun, Beicheng
PMID: 29666149
Journal: J Hepatol. 2018 Sep;69(3):654-665.
Title: Human liver infiltrating gammadelta T cells are composed of clonally expanded circulating and tissue-resident populations.
Author: Hunter, Stuart|Willcox, Carrie R|Davey, Martin S|Kasatskaya, Sofya A|Jeffery, Hannah C|Chudakov, Dmitriy M|Oo, Ye H|Willcox, Benjamin E
PMID: 29758330
Journal: Front Immunol. 2018 May 9;9:1009.
Title: IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.
Author: Easom, Nicholas J W|Stegmann, Kerstin A|Swadling, Leo|Pallett, Laura J|Burton, Alice R|Odera, Dennis|Schmidt, Nathalie|Huang, Wei-Chen|Fusai, Giuseppe|Davidson, Brian|Maini, Mala K
PMID: 29867983