Primary Site >> Colorectal Cancer

Gene >> CD40

Journal: J Biol Chem. 1995 Sep 1;270(35):20824-31.
Title: Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).
Author: Schieven, G L|Wahl, A F|Myrdal, S|Grosmaire, L|Ledbetter, J A
PMID: 7657667
Journal: Hum Gene Ther. 1999 May 20;10(8):1375-87.
Title: Anti-tumor immunity induced by in vivo adenovirus vector-mediated expression of CD40 ligand in tumor cells.
Author: Kikuchi, T|Crystal, R G
PMID: 10365667
Journal: J Exp Med. 1999 Jul 5;190(1):125-33.
Title: Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte response.
Author: Chiodoni, C|Paglia, P|Stoppacciaro, A|Rodolfo, M|Parenza, M|Colombo, M P
PMID: 10429676
Journal: Eur J Immunol. 1999 Jul;29(7):2148-55.
Title: CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth.
Author: Esche, C|Gambotto, A|Satoh, Y|Gerein, V|Robbins, P D|Watkins, S C|Lotze, M T|Shurin, M R
PMID: 10427977
Journal: Blood. 2000 Jul 1;96(1):91-9.
Title: Dendritic cells modified to express CD40 ligand elicit therapeutic immunity against preexisting murine tumors.
Author: Kikuchi, T|Moore, M A|Crystal, R G
PMID: 10891436
Journal: Hum Gene Ther. 2000 Sep 1;11(13):1851-62.
Title: Combination of interleukin 12 and interferon alpha gene therapy induces a synergistic antitumor response against colon and renal cell carcinoma.
Author: Mendiratta, S K|Quezada, A|Matar, M|Thull, N M|Bishop, J S|Nordstrom, J L|Pericle, F
PMID: 10986558
Journal: Gene Ther. 2000 Sep;7(17):1467-76.
Title: In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity.
Author: Sun, Y|Peng, D|Lecanda, J|Schmitz, V|Barajas, M|Qian, C|Prieto, J
PMID: 11001366
Journal: J Immunother. 2001 Mar-Apr;24(2):130-7.
Title: Dendritic cell infiltration in colon cancer.
Author: Schwaab, T|Weiss, J E|Schned, A R|Barth, R J Jr
PMID: 11265770
Journal: Int J Cancer. 2001 Jul 1;93(1):6-11.
Title: Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens.
Author: Linnebacher, M|Gebert, J|Rudy, W|Woerner, S|Yuan, Y P|Bork, P|von Knebel Doeberitz, M
PMID: 11391614
Journal: J Immunother (1991). 2001 Mar;24(2):130-137.
Title: Dendritic Cell Infiltration in Colon Cancer.
Author: Schwaab, Thomas|Weiss, Julia E.|Schned, Alan R.|Barth, Richard J. Jr
PMID: 11449069
Journal: J Immunol. 2001 Oct 15;167(8):4560-5.
Title: A dual-function DNA vaccine encoding carcinoembryonic antigen and CD40 ligand trimer induces T cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice.
Author: Xiang, R|Primus, F J|Ruehlmann, J M|Niethammer, A G|Silletti, S|Lode, H N|Dolman, C S|Gillies, S D|Reisfeld, R A
PMID: 11591784
Journal: Int J Cancer. 2002 Sep 1;101(1):61-8.
Title: Inhibition of CD40 expression and CD40-mediated dendritic cell function by tumor-derived IL-10.
Author: Shurin, Michael R|Yurkovetsky, Zoya R|Tourkova, Irina L|Balkir, Levent|Shurin, Galina V
PMID: 12209589
Journal: Ai Zheng. 2002 Oct;21(10):1112-5.
Title: [Inhibition of human glioma cell growth by a soluble recombinant human CD40 ligand].
Author: Gao, Yi-lu|Shi, Hong-zhen|Liu, Mei|Gu, Xiao-song
PMID: 12508655
Journal: J Immunol Methods. 2002 Jun 1;264(1-2):19-28.
Title: Cell surface phenotyping and cytokine production of Epstein-Barr Virus (EBV)-transformed lymphoblastoid cell lines (LCLs).
Author: Wroblewski, Joanne M|Copple, Angela|Batson, Lydia P|Landers, Cheri D|Yannelli, John R
PMID: 12191505
Journal: J Immunol. 2002 May 15;168(10):4846-53.
Title: Modulation of dendritic cell differentiation and maturation by decoy receptor 3.
Author: Hsu, Tsui-Ling|Chang, Yung-Chi|Chen, Siu-Ju|Liu, Yong-Jun|Chiu, Allen W|Chio, Chung-Ching|Chen, Lieping|Hsieh, Shie-Liang
PMID: 11994433
Journal: Clin Cancer Res. 2002 Apr;8(4):1147-51.
Title: Increased expression of CD40 ligand on activated T cells of patients with colon cancer.
Author: Buning, Carsten|Kruger, Katrin|Sieber, Thomas|Schoeler, Dagmar|Schriever, Folke
PMID: 11948126
Journal: J Immunol. 2003 Jan 1;170(1):99-106.
Title: OX40 ligand-transduced tumor cell vaccine synergizes with GM-CSF and requires CD40-Apc signaling to boost the host T cell antitumor response.
Author: Gri, Giorgia|Gallo, Elena|Di Carlo, Emma|Musiani, Piero|Colombo, Mario P
PMID: 12496388
Journal: J Immunol. 2003 Dec 1;171(11):5842-52.
Title: Dendritic cell-induced activation of adaptive and innate antitumor immunity.
Author: van den Broeke, Leon T|Daschbach, Emily|Thomas, Elaine K|Andringa, Gerda|Berzofsky, Jay A
PMID: 14634094
Journal: J Cell Biochem. 2004 Feb 1;91(2):410-22.
Title: Transcriptional regulation of TNF family receptors and Bcl-2 family by chemotherapeutic agents in murine CT26 cells.
Author: Choi, Kyoung-Han|Choi, Hye Young|Ko, Jae-Kyun|Park, Sung-Shin|Kim, Yong-Nyun|Kim, Chul-Woo
PMID: 14743399
Journal: Novartis Found Symp. 2004;256:241-54; discussion 254-69.
Title: In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.
Author: Vicari, Alain P|Vanbervliet, Beatrice|Massacrier, Catherine|Chiodoni, Claudia|Vaure, Celine|Ait-Yahia, Smina|Dercamp, Christophe|Matsos, Fabien|Reynard, Olivier|Taverne, Catherine|Merle, Philippe|Colombo, Mario P|O'Garra, Anne|Trinchieri, Giorgio|Caux, Ch
PMID: 15027495
Journal: Cancer Res. 2004 Jul 15;64(14):4995-5003.
Title: Dendritic cells pulsed with an anti-idiotype antibody mimicking carcinoembryonic antigen (CEA) can reverse immunological tolerance to CEA and induce antitumor immunity in CEA transgenic mice.
Author: Saha, Asim|Chatterjee, Sunil K|Foon, Kenneth A|Primus, F James|Sreedharan, Sunil|Mohanty, Kartik|Bhattacharya-Chatterjee, Malaya
PMID: 15256474
Journal: Cancer Gene Ther. 2004 Dec;11(12):808-18.
Title: Immune properties of recombinant vaccinia virus encoding CD154 (CD40L) are determined by expression of virally encoded CD40L and the presence of CD40L protein in viral particles.
Author: Bereta, Michal|Bereta, Joanna|Park, Jonas|Medina, Freddy|Kwak, Heesun|Kaufman, Howard L
PMID: 15359290
Journal: Leuk Lymphoma. 2004 Jun;45(6):1239-45.
Title: Coexpression of CD40 and CD40L on B lymphoma and carcinoma cells: an autocrine anti-apoptotic role.
Author: Voorzanger-Rousselot, Nathalie|Blay, Jean-Yves
PMID: 15360007
Journal: Scand J Immunol. 2004 Nov;60(5):449-54.
Title: Expression of interleukin-22 in murine carcinoma cells did not influence tumour growth in vivo but did improve survival of the inoculated hosts.
Author: Nagakawa, H|Shimozato, O|Yu, L|Takiguchi, Y|Tatsumi, K|Kuriyama, T|Tagawa, M
PMID: 15541036
Journal: Int J Cancer. 2005 Nov 20;117(4):574-86.
Title: Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells.
Author: Shah, Sangeeta|Divekar, Anagha A|Hilchey, Shannon P|Cho, Hyun-Mi|Newman, Corliss L|Shin, Seung-Uon|Nechustan, Hovav|Challita-Eid, Pia M|Segal, Benjamin M|Yi, Kyung Hee|Rosenblatt, Joseph D
PMID: 15912532
Journal: Cancer Res. 2005 May 1;65(9):3942-9.
Title: Natural killer and NK-Like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96.
Author: Pilla, Lorenzo|Squarcina, Paola|Coppa, Jorgelina|Mazzaferro, Vincenzo|Huber, Veronica|Pende, Daniela|Maccalli, Cristina|Sovena, Gloria|Mariani, Luigi|Castelli, Chiara|Parmiani, Giorgio|Rivoltini, Licia
PMID: 15867395
Journal: Drugs. 2007;67(3):333-50.
Title: Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma.
Author: Fanale, Michelle A|Younes, Anas
PMID: 17335294
Journal: Int J Cancer. 2007 Sep 15;121(6):1373-81.
Title: CD40-mediated death and cytokine secretion in colorectal cancer: a potential target for inflammatory tumour cell killing.
Author: Georgopoulos, Nikolaos T|Merrick, Alison|Scott, Nigel|Selby, Peter J|Melcher, Alan|Trejdosiewicz, Ludwik K
PMID: 17534894
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2007 Apr;27(4):492-5.
Title: [Effects of two different antigen-loading methods on the activity of dendritic cell vaccine for colorectal carcinoma cell inhibition in vitro].
Author: Huang, Hao|Wang, Hang|Wu, Zi-qing|You, Chang-xuan|Luo, Rong-cheng|Yong, Liu|Hermonat, Paul L
PMID: 17545041
Journal: Int J Cancer. 2008 Jun 15;122(12):2842-50.
Title: Reverse transcriptase inhibitors induce cell differentiation and enhance the immunogenic phenotype in human renal clear-cell carcinoma.
Author: Landriscina, Matteo|Altamura, Settimia Anna|Roca, Leonarda|Gigante, Margherita|Piscazzi, Annamaria|Cavalcanti, Elisabetta|Costantino, Eleonora|Barone, Carlo|Cignarelli, Mauro|Gesualdo, Loreto|Ranieri, Elena
PMID: 18351578
Journal: Cell Immunol. 2008 May-Jun;253(1-2):102-9.
Title: Expression of CD40 and growth-inhibitory activity of CD40 ligand in colon cancer ex vivo.
Author: Wu, Yugang|Wang, Liang|He, Xiaozhou|Xu, Haiyan|Zhou, Lechang|Zhao, Fang|Zhang, Yanyun
PMID: 18603231
Journal: Proc Natl Acad Sci U S A. 2009 May 5;106(18):7513-8.
Title: Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer.
Author: Zhang, Meili|Yao, Zhengsheng|Dubois, Sigrid|Ju, Wei|Muller, Jurgen R|Waldmann, Thomas A
PMID: 19383782
Journal: J Immunol. 2009 Aug 1;183(3):1911-20.
Title: CD1d-based combination therapy eradicates established tumors in mice.
Author: Teng, Michele W L|Sharkey, Janelle|McLaughlin, Nicole M|Exley, Mark A|Smyth, Mark J
PMID: 19620318
Journal: Immunopharmacol Immunotoxicol. 2012 Jun;34(3):465-9.
Title: Induction of tolerogenic dendritic cells by IL-6-secreting CT26 colon carcinoma.
Author: Alshamsan, Aws
PMID: 21999714
Journal: Hepatogastroenterology. 2013 Jan-Feb;60(121):83-8.
Title: Infiltration of CD40-positive tumor-associated macrophages indicates a favorable prognosis in colorectal cancer patients.
Author: Kinouchi, Makoto|Miura, Koh|Mizoi, Takayuki|Ishida, Kazuyuki|Fujibuchi, Wataru|Sasaki, Hiroyuki|Ohnuma, Shinobu|Saito, Kazuya|Katayose, Yu|Naitoh, Takeshi|Motoi, Fuyuhiko|Shiiba, Ken-ichi|Egawa, Shinichi|Shibata, Chikashi|Unno, Michiaki
PMID: 22687258
Journal: Zhongguo Zhong Yao Za Zhi. 2013 Apr;38(7):1056-60.
Title: [Effect of Achyranthes bidentata polysaccharides stimulated dendritic cells co-cultured with cytokine induced killer cells against SW480 cells].
Author: Zhou, Zhi-Dong|Xia, Da-Jing
PMID: 23847957
Journal: Zhonghua Zhong Liu Za Zhi. 2014 Mar;36(3):177-82.
Title: [Anti-tumor effect of Sendai virus Tianjin strain defective interfering particles on tumor-bearing mice].
Author: Shi, Liying|Chen, Jun|Zhong, Qiping|Geng, Peng|He, Jianmin
PMID: 24785276
Journal: Leuk Res. 2014 Aug;38(8):948-54.
Title: Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers.
Author: Westwood, Jennifer A|Matthews, Geoffrey M|Shortt, Jake|Faulkner, David|Pegram, Hollie J|Duong, Connie P M|Chesi, Marta|Bergsagel, P Leif|Sharp, Leslie L|Huhn, Richard D|Darcy, Phillip K|Johnstone, Ricky W|Kershaw, Michael H
PMID: 24934848
Journal: Int J Biol Markers. 2014 Sep 30;29(3):e261-7.
Title: Potential role of soluble CD40 ligand as inflammatory biomarker in colorectal cancer patients.
Author: Dymicka-Piekarska, Violetta|Korniluk, Aleksandra|Gryko, Mariusz|Siergiejko, Elzbieta|Kemona, Halina
PMID: 24706377
Journal: Cancer Immunol Res. 2015 Jan;3(1):85-95.
Title: Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment.
Author: Danelli, Luca|Frossi, Barbara|Gri, Giorgia|Mion, Francesca|Guarnotta, Carla|Bongiovanni, Lucia|Tripodo, Claudio|Mariuzzi, Laura|Marzinotto, Stefania|Rigoni, Alice|Blank, Ulrich|Colombo, Mario P|Pucillo, Carlo E
PMID: 25351848
Journal: Biomaterials. 2015 Aug;61:33-40.
Title: Polymeric microparticles for sustained and local delivery of antiCD40 and antiCTLA-4 in immunotherapy of cancer.
Author: Rahimian, Sima|Fransen, Marieke F|Kleinovink, Jan Willem|Amidi, Maryam|Ossendorp, Ferry|Hennink, Wim E
PMID: 25993015
Journal: Tumour Biol. 2016 Aug;37(8):11359-64.
Title: Body composition of the host influences dendritic cell phenotype in patients treated for colorectal cancer.
Author: Malietzis, George|Lee, Gui Han|Al-Hassi, Hafid O|Bernardo, David|Blakemore, Alexandra I F|Kennedy, Robin H|Moorghen, Morgan|Jenkins, John T|Knight, Stella C
PMID: 26960692
Journal: Eur J Cell Biol. 2016 Jun-Jul;95(6-7):219-27.
Title: Induction of immunogenic cell death by radiation-upregulated karyopherin alpha 2 in vitro.
Author: Song, Kyung-Hee|Jung, Seung-Youn|Kang, Seong-Mook|Kim, Mi-Hyoung|Ahn, Jiyeon|Hwang, Sang-Gu|Lee, Jun-Ho|Lim, Dae-Seog|Nam, Seon Young|Song, Jie-Young
PMID: 27107455
Journal: Oncol Res Treat. 2016;39(6):346-50.
Title: Immunotherapy of Colorectal Cancer.
Author: Jager, Dirk|Halama, Niels|Zornig, Inka|Klug, Paula|Krauss, Jurgen|Haag, Georg-Martin
PMID: 27259331
Journal: Cancer Immunol Immunother. 2016 Aug;65(8):919-29.
Title: Regulation of CD40 signaling in colon cancer cells and its implications in clinical tissues.
Author: Zhou, Yan|Zhou, Shu-Xian|Gao, Long|Li, Xiao-An
PMID: 27262846
Journal: Cancer Cell. 2016 Sep 12;30(3):377-390.
Title: T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.
Author: Marigo, Ilaria|Zilio, Serena|Desantis, Giacomo|Mlecnik, Bernhard|Agnellini, Andrielly H R|Ugel, Stefano|Sasso, Maria Stella|Qualls, Joseph E|Kratochvill, Franz|Zanovello, Paola|Molon, Barbara|Ries, Carola H|Runza, Valeria|Hoves, Sabine|Bilocq, Amelie M|Bi
PMID: 27622331
Journal: Acta Biomater. 2017 Nov;63:96-109.
Title: Pro-inflammatory chitosan/poly(gamma-glutamic acid) nanoparticles modulate human antigen-presenting cells phenotype and revert their pro-invasive capacity.
Author: Castro, Flavia|Pinto, Marta L|Silva, Andreia M|Pereira, Catarina L|Teixeira, Graciosa Q|Gomez-Lazaro, Maria|Santos, Susana G|Barbosa, Mario A|Goncalves, Raquel M|Oliveira, Maria J
PMID: 28919508
Journal: J BUON. 2017 Jul-Aug;22(4):894-899.
Title: Expression of CD40/CD40L in colon cancer, and its effect on proliferation and apoptosis of SW48 colon cancer cells.
Author: Pang, Xueqin|Zhang, Lifeng|Wu, Jiaming|Ma, Chen|Mu, Chuanyong|Zhang, Guangbo|Chen, Weichang
PMID: 29155517
Journal: Drug Des Devel Ther. 2018 Mar 29;12:657-671.
Title: The apoptotic effects of Brucea javanica fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-kappaB translocation.
Author: Bagheri, Elham|Hajiaghaalipour, Fatemeh|Nyamathulla, Shaik|Salehen, Nur'Ain
PMID: 29636600
Journal: J Immunother. 2018 Nov/Dec;41(9):385-398.
Title: The Hexavalent CD40 Agonist HERA-CD40L Induces T-Cell-mediated Antitumor Immune Response Through Activation of Antigen-presenting Cells.
Author: Merz, Christian|Sykora, Jaromir|Marschall, Viola|Richards, David M|Heinonen, Karl|Redondo Muller, Mauricio|Thiemann, Meinolf|Schnyder, Tim|Fricke, Harald|Hill, Oliver|Gieffers, Christian
PMID: 30273198