Primary Site >> Colorectal Cancer

Gene >> CCL5

Journal: Inflamm Bowel Dis. 1996 Summer;2(2):88-96.
Title: Chemokines in Inflammatory Bowel Disease Mucosa: Expression of RANTES, Macrophage Inflammatory Protein (MIP)-1alpha, MIP-1beta, and gamma-Interferon-Inducible Protein-10 by Macrophages, Lymphocytes, Endothelial Cells, and Granulomas.
Author: Grimm, M C|Doe, W F
PMID: 23282513
Journal: J Immunother. 1997 Sep;20(5):372-6.
Title: Oncogene and cytokine expression of human colorectal tumors responding to immunotherapy.
Author: Doran, T|Stuhlmiller, H|Kim, J A|Martin, E W Jr|Triozzi, P L
PMID: 9336744
Journal: Int J Oncol. 1997 Mar;10(3):481-6.
Title: Effects of thymic peptides, in vitro, on the impaired immunocytotoxicity of peripheral blood mononuclear cells from tumor patients.
Author: Eckert, K|Mayer, G|Stange, R|Kalden, M|Krasagakis, K|Maurer, H
PMID: 21533400
Journal: Gene Ther. 2000 Sep;7(17):1467-76.
Title: In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity.
Author: Sun, Y|Peng, D|Lecanda, J|Schmitz, V|Barajas, M|Qian, C|Prieto, J
PMID: 11001366
Journal: Int J Oncol. 2002 Jul;21(1):85-93.
Title: Human tumor cell infection by Newcastle Disease Virus leads to upregulation of HLA and cell adhesion molecules and to induction of interferons, chemokines and finally apoptosis.
Author: Washburn, B|Schirrmacher, V
PMID: 12063554
Journal: Ann Surg. 2002 Sep;236(3):337-42; discussion 342-3.
Title: Efficacy of multiagent herpes simplex virus amplicon-mediated immunotherapy as adjuvant treatment for experimental hepatic cancer.
Author: Delman, Keith A|Zager, Jonathan S|Bennett, Joseph J|Malhotra, Sandeep|Ebright, Michael I|McAuliffe, Priscilla F|Halterman, Marc W|Federoff, Howard J|Fong, Yuman
PMID: 12192320
Journal: Int J Cancer. 2005 Oct 10;116(6):949-56.
Title: Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma.
Author: Musha, Hiroaki|Ohtani, Haruo|Mizoi, Takayuki|Kinouchi, Makoto|Nakayama, Takashi|Shiiba, Kennichi|Miyagawa, Kikuo|Nagura, Hiroshi|Yoshie, Osamu|Sasaki, Iwao
PMID: 15856455
Journal: J Gastroenterol Hepatol. 2006 Sep;21(9):1412-8.
Title: Secretion of RANTES (CCL5) and interleukin-10 from mesenteric adipose tissue and from creeping fat in Crohn's disease: regulation by steroid treatment.
Author: Schaffler, Andreas|Furst, Alois|Buchler, Christa|Paul, Gisela|Rogler, Gerhard|Scholmerich, Jurgen|Herfarth, Hans
PMID: 16911685
Journal: J Immunother. 2007 Sep;30(6):614-23.
Title: Rofecoxib has different effects on chemokine production in colorectal cancer cells and tumor immune splenocytes.
Author: Walmesley, Alice J|Zweiri, Jehad|Christmas, Stephen E|Watson, Alastair J M
PMID: 17667525
Journal: Methods Enzymol. 2009;460:105-21.
Title: Expression of chemokines and chemokine receptors in human colon cancer.
Author: Erreni, Marco|Bianchi, Paolo|Laghi, Luigi|Mirolo, Massimiliano|Fabbri, Marco|Locati, Massimo|Mantovani, Alberto|Allavena, Paola
PMID: 19446722
Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2009 Aug;32(4):223-30.
Title: [Discovery of a new type of human regulatory T cell lines, HOZOTs, and their clinical application]].
Author: Nakamura, Shuji
PMID: 19721342
Journal: J Immunol. 2010 Feb 1;184(3):1630-41.
Title: Tumor microenvironments direct the recruitment and expansion of human Th17 cells.
Author: Su, Xinming|Ye, Jian|Hsueh, Eddy C|Zhang, Yanping|Hoft, Daniel F|Peng, Guangyong
PMID: 20026736
Journal: PLoS One. 2011;6(12):e28842.
Title: CCL5 neutralization restricts cancer growth and potentiates the targeting of PDGFRbeta in colorectal carcinoma.
Author: Cambien, Beatrice|Richard-Fiardo, Peggy|Karimdjee, Babou F|Martini, Violette|Ferrua, Bernard|Pitard, Bruno|Schmid-Antomarchi, Heidy|Schmid-Alliana, Annie
PMID: 22205974
Journal: PLoS One. 2011 Jan 7;6(1):e15366.
Title: The inflammatory microenvironment in colorectal neoplasia.
Author: McLean, Mairi H|Murray, Graeme I|Stewart, Keith N|Norrie, Gillian|Mayer, Claus|Hold, Georgina L|Thomson, John|Fyfe, Nicky|Hope, Mairi|Mowat, N Ashley G|Drew, Janice E|El-Omar, Emad M
PMID: 21249124
Journal: Mol Cancer Res. 2011 Feb;9(2):133-48.
Title: S100A8/A9 activate key genes and pathways in colon tumor progression.
Author: Ichikawa, Mie|Williams, Roy|Wang, Ling|Vogl, Thomas|Srikrishna, Geetha
PMID: 21228116
Journal: Mol Carcinog. 2012 Nov;51(11):869-80.
Title: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice.
Author: Park, Heesook|Kim, Minhee|Kwon, Gyoo Taik|Lim, Do Young|Yu, Rina|Sung, Mi-Kyung|Lee, Ki Won|Daily, James W 3rd|Park, Jung Han Yoon
PMID: 21919080
Journal: Mol Biol Rep. 2012 May;39(5):5727-36.
Title: Novel multiplex method to assess insulin, leptin and adiponectin regulation of inflammatory cytokines associated with colon cancer.
Author: Farquharson, Andrew J|Steele, Robert J|Carey, Frank A|Drew, Janice E
PMID: 22193626
Journal: Cancer Res. 2012 Mar 1;72(5):1092-102.
Title: Tumor-derived chemokine CCL5 enhances TGF-beta-mediated killing of CD8(+) T cells in colon cancer by T-regulatory cells.
Author: Chang, Li-Yuan|Lin, Yung-Chang|Mahalingam, Jayashri|Huang, Ching-Tai|Chen, Ten-Wen|Kang, Chiao-Wen|Peng, Hui-Min|Chu, Yu-Yi|Chiang, Jy-Ming|Dutta, Avijit|Day, Yuan-Ji|Chen, Tse-Ching|Yeh, Chau-Ting|Lin, Chun-Yen
PMID: 22282655
Journal: J Nutr. 2012 May;142(5):859-65.
Title: Dietary cholecalciferol and calcium levels in a Western-style defined rodent diet alter energy metabolism and inflammatory responses in mice.
Author: Bastie, Claire C|Gaffney-Stomberg, Erin|Lee, Ting-Wen A|Dhima, Elena|Pessin, Jeffrey E|Augenlicht, Leonard H
PMID: 22437564
Journal: Cancer Res. 2012 Aug 1;72(15):3735-43.
Title: NF-kappaB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells.
Author: Muthuswamy, Ravikumar|Berk, Erik|Junecko, Beth Fallert|Zeh, Herbert J|Zureikat, Amer H|Normolle, Daniel|Luong, The Minh|Reinhart, Todd A|Bartlett, David L|Kalinski, Pawel
PMID: 22593190
Journal: Oncogene. 2013 Feb 14;32(7):849-60.
Title: Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.
Author: Arabzadeh, A|Chan, C|Nouvion, A-L|Breton, V|Benlolo, S|DeMarte, L|Turbide, C|Brodt, P|Ferri, L|Beauchemin, N
PMID: 22469976
Journal: Int J Cancer. 2013 Feb 1;132(3):591-604.
Title: Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
Author: Pickert, Geethanjali|Lim, Hee-Young|Weigert, Andreas|Haussler, Annett|Myrczek, Thekla|Waldner, Maximilian|Labocha, Sandra|Ferreiros, Nerea|Geisslinger, Gerd|Lotsch, Jorn|Becker, Christoph|Brune, Bernhard|Tegeder, Irmgard
PMID: 22753274
Journal: Int Immunol. 2013 Jan;25(1):35-44.
Title: Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Galphai2-deficient mouse.
Author: Gotlind, Yu-Yuan|Fritsch Fredin, Maria|Kumawat, Ashok Kumar|Strid, Hilja|Willen, Roger|Rangel, Ignacio|Bland, Paul W|Hornquist, Elisabeth Hultgren
PMID: 22962436
Journal: J Transl Med. 2013 Mar 26;11:79.
Title: Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68.
Author: Ehrig, Klaas|Kilinc, Mehmet O|Chen, Nanhai G|Stritzker, Jochen|Buckel, Lisa|Zhang, Qian|Szalay, Aladar A
PMID: 23531320
Journal: Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9862-7.
Title: Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer.
Author: Hu, Bo|Elinav, Eran|Huber, Samuel|Strowig, Till|Hao, Liming|Hafemann, Anja|Jin, Chengcheng|Wunderlich, Claudia|Wunderlich, Thomas|Eisenbarth, Stephanie C|Flavell, Richard A
PMID: 23696660
Journal: Neoplasia. 2013 Sep;15(9):998-1008.
Title: STAT3 in epithelial cells regulates inflammation and tumor progression to malignant state in colon.
Author: Nguyen, Andrew V|Wu, Yuan-Yuan|Liu, Qiang|Wang, Donghai|Nguyen, Stephanie|Loh, Ricky|Pang, Joey|Friedman, Kenneth|Orlofsky, Amos|Augenlicht, Leonard|Pollard, Jeffrey W|Lin, Elaine Y
PMID: 24027425
Journal: Oncoimmunology. 2014 Jun 25;3:e29256.
Title: Characterization of an adaptive immune response in microsatellite-instable colorectal cancer.
Author: Boissiere-Michot, Florence|Lazennec, Gwendal|Frugier, Helene|Jarlier, Marta|Roca, Lise|Duffour, Jacqueline|Du Paty, Emilie|Laune, Daniel|Blanchard, France|Le Pessot, Florence|Sabourin, Jean-Christophe|Bibeau, Frederic
PMID: 25101223
Journal: Cell Mol Immunol. 2014 Mar;11(2):150-9.
Title: TLR4 is essential for dendritic cell activation and anti-tumor T-cell response enhancement by DAMPs released from chemically stressed cancer cells.
Author: Fang, Hongliang|Ang, Bing|Xu, Xinyun|Huang, Xiaohui|Wu, Yanfeng|Sun, Yanping|Wang, Wenying|Li, Nan|Cao, Xuetao|Wan, Tao
PMID: 24362470
Journal: Oncogene. 2015 Jan 22;34(4):424-35.
Title: A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.
Author: Hansen, M T|Forst, B|Cremers, N|Quagliata, L|Ambartsumian, N|Grum-Schwensen, B|Klingelhofer, J|Abdul-Al, A|Herrmann, P|Osterland, M|Stein, U|Nielsen, G H|Scherer, P E|Lukanidin, E|Sleeman, J P|Grigorian, M
PMID: 24469032
Journal: J Cell Physiol. 2015 Aug;230(8):1883-94.
Title: Chemokine (C-C Motif) Ligand 5 is Involved in Tumor-Associated Dendritic Cell-Mediated Colon Cancer Progression Through Non-Coding RNA MALAT-1.
Author: Kan, Jung-Yu|Wu, Deng-Chyang|Yu, Fang-Jung|Wu, Cheng-Ying|Ho, Ya-Wen|Chiu, Yen-Jung|Jian, Shu-Fang|Hung, Jen-Yu|Wang, Jaw-Yuan|Kuo, Po-Lin
PMID: 25546229
Journal: Oncotarget. 2015 Feb 20;6(5):2981-91.
Title: Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration.
Author: Zumwalt, Timothy J|Arnold, Mildred|Goel, Ajay|Boland, C Richard
PMID: 25671296
Journal: J Nucl Med. 2015 Apr;56(4):600-6.
Title: Mesenchymal stem cell-mediated, tumor stroma-targeted radioiodine therapy of metastatic colon cancer using the sodium iodide symporter as theranostic gene.
Author: Knoop, Kerstin|Schwenk, Nathalie|Schmohl, Kathrin|Muller, Andrea|Zach, Christian|Cyran, Clemens|Carlsen, Janette|Boning, Guido|Bartenstein, Peter|Goke, Burkhard|Wagner, Ernst|Nelson, Peter J|Spitzweg, Christine
PMID: 25745085
Journal: Cancer Biol Ther. 2015;16(5):671-7.
Title: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors.
Author: Crucitti, Antonio|Corbi, Maddalena|Tomaiuolo, Pasquina Mc|Fanali, Caterina|Mazzari, Andrea|Lucchetti, Donatella|Migaldi, Mario|Sgambato, Alessandro
PMID: 25875151
Journal: BMC Cancer. 2015 Mar 14;15:123.
Title: Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma.
Author: Henry, Curtis J|Sedjo, Rebecca L|Rozhok, Andrii|Salstrom, Jennifer|Ahnen, Dennis|Levin, Theodore R|D'Agostino, Ralph Jr|Haffner, Steven|DeGregori, James|Byers, Tim
PMID: 25884547
Journal: Pol Arch Med Wewn. 2015;125(6):443-51. Epub 2015 May 28.
Title: Preoperative serum chemokine (C-C motif) ligand 2 levels and prognosis in colorectal cancer.
Author: Szczepanik, Antoni M|Siedlar, Maciej|Szura, Miroslaw|Kibil, Wojciech|Brzuszkiewicz, Karolina|Brandt, Philip|Kulig, Jan
PMID: 26020569
Journal: J Immunother Cancer. 2016 Dec 20;4:93.
Title: Advances in immunotherapeutic strategies for colorectal cancer commentary on: tumoral immune cell exploitation in colorectal cancer metastases can be targeted effectively by anti-CCR5 therapy in cancer patients by Halama et al.
Author: Deming, Dustin A
PMID: 28031821
Journal: Cancer Cell. 2016 Apr 11;29(4):587-601.
Title: Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients.
Author: Halama, Niels|Zoernig, Inka|Berthel, Anna|Kahlert, Christoph|Klupp, Fee|Suarez-Carmona, Meggy|Suetterlin, Thomas|Brand, Karsten|Krauss, Juergen|Lasitschka, Felix|Lerchl, Tina|Luckner-Minden, Claudia|Ulrich, Alexis|Koch, Moritz|Weitz, Juergen|Schneider, Ma
PMID: 27070705
Journal: BMC Cancer. 2016 Mar 7;16:189.
Title: Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation.
Author: Shukla, Pradeep K|Chaudhry, Kamaljit K|Mir, Hina|Gangwar, Ruchika|Yadav, Nikki|Manda, Bhargavi|Meena, Avtar S|Rao, RadhaKrishna
PMID: 26951793
Journal: Biochem Biophys Res Commun. 2016 Jan 22;469(4):878-83.
Title: Heparanase augments inflammatory chemokine production from colorectal carcinoma cell lines.
Author: Tsunekawa, Naoki|Higashi, Nobuaki|Kogane, Yusuke|Waki, Michihiko|Shida, Hiroaki|Nishimura, Yoshio|Adachi, Hayamitsu|Nakajima, Motowo|Irimura, Tatsuro
PMID: 26713365
Journal: Oncogene. 2016 May 19;35(20):2634-44.
Title: Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.
Author: Sanchez-Lopez, E|Flashner-Abramson, E|Shalapour, S|Zhong, Z|Taniguchi, K|Levitzki, A|Karin, M
PMID: 26364612
Journal: Ann Surg Oncol. 2016 Feb;23(2):655-62.
Title: Complement Inhibition: A Novel Form of Immunotherapy for Colon Cancer.
Author: Downs-Canner, Stephanie|Magge, Deepa|Ravindranathan, Roshni|O'Malley, Mark E|Francis, Lily|Liu, Zuqiang|Sheng Guo, Z|Obermajer, Natasa|Bartlett, David L
PMID: 26289805
Journal: Gut. 2017 Apr;66(4):692-704.
Title: Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer.
Author: Amicarella, F|Muraro, M G|Hirt, C|Cremonesi, E|Padovan, E|Mele, V|Governa, V|Han, J|Huber, X|Droeser, R A|Zuber, M|Adamina, M|Bolli, M|Rosso, R|Lugli, A|Zlobec, I|Terracciano, L|Tornillo, L|Zajac, P|Eppenberger-Castori, S|Trapani, F|Oertli, D|Iezzi, G
PMID: 26719303
Journal: Cell Death Dis. 2017 May 25;8(5):e2819.
Title: Human MSCs promotes colorectal cancer epithelial-mesenchymal transition and progression via CCL5/beta-catenin/Slug pathway.
Author: Chen, Ke|Liu, Qianqian|Tsang, Lai Ling|Ye, Qiao|Chan, Hsiao Chang|Sun, Yunwei|Jiang, Xiaohua
PMID: 28542126
Journal: Cytokine. 2017 Nov;99:35-42.
Title: Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps.
Author: Johdi, Nor Adzimah|Mazlan, Luqman|Sagap, Ismail|Jamal, Rahman
PMID: 28689023
Journal: Oncotarget. 2017 Aug 2;8(59):99451-99469.
Title: Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species.
Author: Roberts, Jane L|Poklepovic, Andrew|Booth, Laurence
PMID: 29245915
Journal: Gut. 2018 Feb 6. pii: gutjnl-2016-313498.
Title: Gut microbiota modulate T cell trafficking into human colorectal cancer.
Author: Cremonesi, Eleonora|Governa, Valeria|Garzon, Jesus Francisco Glaus|Mele, Valentina|Amicarella, Francesca|Muraro, Manuele Giuseppe|Trella, Emanuele|Galati-Fournier, Virginie|Oertli, Daniel|Daster, Silvio Raffael|Droeser, Raoul A|Weixler, Benjamin|Bolli, Ma
PMID: 29437871
Journal: Oncotarget. 2018 Feb 28;9(21):15691-15704.
Title: Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency.
Author: Rayes, Roni F|Milette, Simon|Fernandez, Maria Celia|Ham, Boram|Wang, Ni|Bourdeau, France|Perrino, Stephanie|Yakar, Shoshana|Brodt, Pnina
PMID: 29644002
Journal: Oncogene. 2018 Jul;37(28):3790-3805.
Title: Collagen IV-conveyed signals can regulate chemokine production and promote liver metastasis.
Author: Vaniotis, George|Rayes, Roni F|Qi, Shu|Milette, Simon|Wang, Ni|Perrino, Stephanie|Bourdeau, France|Nystrom, Hanna|He, Yi|Lamarche-Vane, Nathalie|Brodt, Pnina
PMID: 29651051
Journal: World J Gastroenterol. 2018 May 14;24(18):1995-2008.
Title: Microbiota modification by probiotic supplementation reduces colitis associated colon cancer in mice.
Author: Mendes, Maria Carolina S|Paulino, Daiane Sm|Brambilla, Sandra R|Camargo, Juliana A|Persinoti, Gabriela F|Carvalheira, Jose Barreto C
PMID: 29760543
Journal: Cytokine. 2018 Oct;110:435-441.
Title: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer.
Author: Krzystek-Korpacka, Malgorzata|Zawadzki, Marek|Kapturkiewicz, Bartosz|Lewandowska, Paulina|Bednarz-Misa, Iwona|Gorska, Sabina|Witkiewicz, Wojciech|Gamian, Andrzej
PMID: 29801973
Journal: Front Nutr. 2018 May 31;5:37.
Title: Dietary Walnuts Protect Against Obesity-Driven Intestinal Stem Cell Decline and Tumorigenesis.
Author: Guan, Fangxia|Tabrizian, Tahmineh|Novaj, Ardijana|Nakanishi, Masako|Rosenberg, Daniel W|Huffman, Derek M
PMID: 29904634
Journal: Cell Death Dis. 2018 Jul 10;9(7):766.
Title: CCL5-deficiency enhances intratumoral infiltration of CD8(+) T cells in colorectal cancer.
Author: Zhang, Shengbo|Zhong, Ming|Wang, Chao|Xu, Yanjie|Gao, Wei-Qiang|Zhang, Yan
PMID: 29991744
Journal: Cell Physiol Biochem. 2018;48(2):475-490.
Title: Distinguishable Prognostic Signatures of Left- and Right-Sided Colon Cancer: a Study Based on Sequencing Data.
Author: Liang, Liang|Zeng, Jiang-Hui|Qin, Xin-Gan|Chen, Jun-Qiang|Luo, Dian-Zhong|Chen, Gang
PMID: 30016783
Journal: J Cachexia Sarcopenia Muscle. 2018 Oct 3.
Title: Peritumoural adipose tissue pro-inflammatory cytokines are associated with tumoural growth factors in cancer cachexia patients.
Author: Neto, Nelson Inacio Pinto|Murari, Ariene Soares de Pinho|Oyama, Lila Missae|Otoch, Jose Pinhata|Alcantara, Paulo Sergio Martins|Tokeshi, Flavio|Figueredo, Raquel Galvao|Alves, Michele Joana|Lima, Joanna Darck Carola Correia|Matos-Neto, Emidio Marques de|S
PMID: 30284380