Primary Site >> Liver Cancer

Gene >> CCL16

Journal: J Hered. 1987 Nov-Dec;78(6):361-5.
Title: New mutation causing hereditary hepatitis in the laboratory rat.
Author: Yoshida, M C|Masuda, R|Sasaki, M|Takeichi, N|Kobayashi, H|Dempo, K|Mori, M
PMID: 3429843
Journal: Jpn J Cancer Res. 1988 Jul;79(7):828-35.
Title: High susceptibility to hepatocellular carcinoma development in LEC rats with hereditary hepatitis.
Author: Masuda, R|Yoshida, M C|Sasaki, M|Dempo, K|Mori, M
PMID: 2459092
Journal: Jpn J Cancer Res. 1988 Feb;79(2):250-4.
Title: A transplantable cell line derived from spontaneous hepatocellular carcinoma of the hereditary hepatitis LEC rat.
Author: Masuda, R|Yoshida, M C|Sasaki, M|Dempo, K|Mori, M
PMID: 3130360
Journal: Carcinogenesis. 1988 Sep;9(9):1569-72.
Title: Metabolic predisposition of a novel mutant (LEC rats) to hereditary hepatitis and hepatoma: alterations of the drug metabolizing enzymes.
Author: Sugiyama, T|Takeichi, N|Kobayashi, H|Yoshida, M C|Sasaki, M|Taniguchi, N
PMID: 2900702
Journal: Int J Biochem. 1988;20(10):1171-6.
Title: Hepatoma-associated alterations of serum alpha 1-antitrypsin in hereditary hepatitis LEC rats as a new animal model of liver disease.
Author: Masuda, R|Sugiyama, T|Taniguchi, N|Yoshida, M C|Sasaki, M
PMID: 2854794
Journal: Jpn J Cancer Res. 1988 Jan;79(1):5-8.
Title: Spontaneous occurrence of placental glutathione S-transferase-positive foci in the livers of LEC rats.
Author: Oyamada, M|Dempo, K|Fujimoto, Y|Takahashi, H|Satoh, M I|Mori, M|Masuda, R|Yoshida, M C|Satoh, K|Sato, K
PMID: 2895758
Journal: Jpn J Cancer Res. 1989 Nov;80(11):1024-7.
Title: Gene expression of placental glutathione S-transferase in hereditary hepatitis and spontaneous hepatocarcinogenesis of LEC strain rats.
Author: Masuda, R|Yoshida, M C|Sasaki, M
PMID: 2481661
Journal: Hokkaido Igaku Zasshi. 1990 Mar;65(2):201-9.
Title: [A study on expression of various oncogenes and tumor-associated genes in LEC rats spontaneously developing hepatitis and hepatoma].
Author: Suzuki, H
PMID: 1694810
Journal: Carcinogenesis. 1990 Oct;11(10):1857-61.
Title: Phenotype of preneoplastic and neoplastic liver lesions during spontaneous liver carcinogenesis of LEC rats.
Author: Sawaki, M|Enomoto, K|Takahashi, H|Nakajima, Y|Mori, M
PMID: 1698569
Journal: Cancer Lett. 1990 Jun 15;51(3):247-50.
Title: High sensitivity of the LEC rat liver to the carcinogenic effect of diethylnitrosamine.
Author: Takahashi, H|Enomoto, K|Nakajima, Y|Mori, M
PMID: 2190688
Journal: Mutat Res. 1990 Aug;244(4):309-16.
Title: Cytochrome P-450 and chromosome damage by cyclophosphamide in LEC strain rats predisposed to hereditary hepatitis and liver cancer.
Author: Masuda, R|Abe, S|Yoshida, M C|Sasaki, M|Sugiyama, T|Taniguchi, N
PMID: 2385246
Journal: Jpn J Cancer Res. 1991 May;82(5):486-9.
Title: Hereditary low level of plasma ceruloplasmin in LEC rats associated with spontaneous development of hepatitis and liver cancer.
Author: Ono, T|Abe, S|Yoshida, M C
PMID: 1905693
Journal: Biochem Biophys Res Commun. 1992 May 15;184(3):1393-7.
Title: Unusual accumulation of copper related to induction of metallothionein in the liver of LEC rats.
Author: Sakurai, H|Fukudome, A|Tawa, R|Kito, M|Takeshima, S|Kimura, M|Otaki, N|Nakajima, K|Hagino, T|Kawano, K
PMID: 1317172
Journal: Jpn J Cancer Res. 1992 Oct;83(10):inside front cover.
Title: The LEC rat--an animal model for human hepatitis and hepatocellular carcinoma.
Author: Thorgeirsson, S S
PMID: 1333464
Journal: Cancer Res. 1993 Sep 1;53(17):3899-902.
Title: N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.
Author: Miyoshi, E|Nishikawa, A|Ihara, Y|Gu, J|Sugiyama, T|Hayashi, N|Fusamoto, H|Kamada, T|Taniguchi, N
PMID: 8240532
Journal: Carcinogenesis. 1993 Apr;14(4):603-5.
Title: Expression of DNA methyltransferase in LEC rats during hepatocarcinogenesis.
Author: Miyoshi, E|Jain, S K|Sugiyama, T|Fujii, J|Hayashi, N|Fusamoto, H|Kamada, T|Taniguchi, N
PMID: 8472322
Journal: Jpn J Cancer Res. 1993 Mar;84(3):219-22.
Title: Abnormal hepatic iron accumulation in LEC rats.
Author: Kato, J|Kohgo, Y|Sugawara, N|Katsuki, S|Shintani, N|Fujikawa, K|Miyazaki, E|Kobune, M|Takeichi, N|Niitsu, Y
PMID: 8387476
Journal: Histochemistry. 1993 Oct;100(4):249-56.
Title: Histochemical demonstration of copper in LEC rat liver.
Author: Fujii, Y|Shimizu, K|Satoh, M|Fujita, M|Fujioka, Y|Li, Y|Togashi, Y|Takeichi, N|Nagashima, K
PMID: 8276638
Journal: Carcinogenesis. 1994 Sep;15(9):1833-7.
Title: Role of copper accumulation and metallothionein induction in spontaneous liver cancer development in LEC rats.
Author: Sawaki, M|Enomoto, K|Hattori, A|Tsuzuki, N|Sugawara, N|Mori, M
PMID: 7522980
Journal: Hum Exp Toxicol. 1994 Dec;13(12):910-2.
Title: Copper-overload causes cancer? The LEC rat: a model for human hepatitis, liver cancer, and much more.
Author: Powell, C J
PMID: 7718314
Journal: Biol Pharm Bull. 1994 May;17(5):591-5.
Title: Abnormal accumulation of copper-metallothionein in the liver and kidney of Long-Evans rats with a cinnamon-like coat color (LEC rats).
Author: Tsujikawa, K|Suzuki, N|Shimaoka, T|Iida, K|Kohama, Y|Otaki, N|Kimura, M|Sugiyama, T|Mimura, T
PMID: 7920414
Journal: Am J Pathol. 1994 Jan;144(1):200-4.
Title: The LEC rat: a model for human hepatitis, liver cancer, and much more.
Author: Mori, M|Hattori, A|Sawaki, M|Tsuzuki, N|Sawada, N|Oyamada, M|Sugawara, N|Enomoto, K
PMID: 8291609
Journal: J Gastroenterol. 1995 Oct;30(5):619-23.
Title: Changes in free radical-metabolizing enzymes and lipid peroxides in the liver of Long-Evans with cinnamon-like coat color rats.
Author: Ohhira, M|Ono, M|Ohhira, M|Sekiya, C|Namiki, M|Fujimoto, Y|Nagao, M|Mori, M
PMID: 8574334
Journal: Jpn J Cancer Res. 1995 Jan;86(1):5-9.
Title: Differing distribution of hepatocyte growth factor-positive cells in the liver of LEC rats with acute hepatitis, chronic hepatitis and hepatoma.
Author: Nakayama, N|Kashiwazaki, H|Kobayashi, N|Hamada, J|Matsumoto, K|Nakamura, T|Takeichi, N
PMID: 7737910
Journal: Carcinogenesis. 1995 Mar;16(3):491-4.
Title: The high hepatocarcinogen susceptibility of LEC rats is genetically independent of abnormal copper accumulation in the liver.
Author: Hattori, A|Sawaki, M|Enomoto, K|Tsuzuki, N|Isomura, H|Kojima, T|Kamibayashi, Y|Sugawara, N|Sugiyama, T|Mori, M
PMID: 7697803
Journal: Biochim Biophys Acta. 1995 Feb 9;1254(3):257-66.
Title: Accumulation of isogloboside and ganglio-N-tetraosyl ceramide having blood group B determinant in the hepatomas of female LEC rats.
Author: Ariga, T|Kasai, N|Miyoshi, I|Yamawaki, M|Scarsdale, J N|Yu, R K|Kasama, T|Taki, T
PMID: 7532009
Journal: Hokkaido Igaku Zasshi. 1995 Jul;70(4):609-21.
Title: [Expression of hepatocyte growth factor (HGF) in LEC rats at various phases of hepatitis and hepatoma].
Author: Nakayama, N
PMID: 7590606
Journal: Jpn J Cancer Res. 1996 Jan;87(1):25-9.
Title: Hepatocellular carcinoma induction in LEC rats by a low dose of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Author: Sone, H|Wakabayashi, K|Kushida, H|Enomoto, K|Mori, M|Takeichi, N|Tsuda, H|Sugimura, T|Nagao, M
PMID: 8609044
Journal: Jpn J Cancer Res. 1996 Apr;87(4):337-41.
Title: Induction of aldose reductase gene expression in LEC rats during the development of the hereditary hepatitis and hepatoma.
Author: Takahashi, M|Hoshi, A|Fujii, J|Miyoshi, E|Kasahara, T|Suzuki, K|Aozasa, K|Taniguchi, N
PMID: 8641963
Journal: Carcinogenesis. 1996 Oct;17(10):2157-61.
Title: Abnormal accumulation of copper in LEC rat liver induces expression of p53 and nuclear matrix-bound p21(waf 1/cip 1).
Author: Obata, H|Sawada, N|Isomura, H|Mori, M
PMID: 8895483
Journal: Jpn J Vet Res. 1997 Nov;45(3):147-51.
Title: Magnetic resonance imaging of hepatocellular carcinoma in Long-Evans cinnamon rats under a magnetic field of 7.05 T.
Author: Asanuma, T|Hirano, Y|Ohkura, K|Kon, Y|Shimokawa, S|Kasai, N|Kuwabara, M
PMID: 9433015
Journal: Eur J Cancer Prev. 1997 Dec;6(6):529-34.
Title: Etheno-DNA base adducts as tools in human cancer aetiology and chemoprevention.
Author: Bartsch, H|Nair, J|Velic, I
PMID: 9496454
Journal: Int J Cancer. 1998 Jan 30;75(3):444-50.
Title: High expression of alpha-1-6 fucosyltransferase during rat hepatocarcinogenesis.
Author: Noda, K|Miyoshi, E|Uozumi, N|Gao, C X|Suzuki, K|Hayashi, N|Hori, M|Taniguchi, N
PMID: 9455807
Journal: Carcinogenesis. 1998 Feb;19(2):331-5.
Title: Chronic liver injury promotes hepatocarcinogenesis of the LEC rat.
Author: Sawaki, M|Hattori, A|Tsuzuki, N|Sugawara, N|Enomoto, K|Sawada, N|Mori, M
PMID: 9498285
Journal: Free Radic Res. 1998 Apr;28(4):383-91.
Title: A high expression of heme oxygenase-1 in the liver of LEC rats at the stage of hepatoma: the possible implication of induction in uninvolved tissue.
Author: Matsumoto, A|Hanayama, R|Nakamura, M|Suzuki, K|Fujii, J|Tatsumi, H|Taniguchi, N
PMID: 9684983
Journal: Free Radic Res. 1998 May;28(5):441-50.
Title: A marked increase in free copper levels in the plasma and liver of LEC rats: an animal model for Wilson disease and liver cancer.
Author: Koizumi, M|Fujii, J|Suzuki, K|Inoue, T|Inoue, T|Gutteridge, J M|Taniguchi, N
PMID: 9702524
Journal: Biochim Biophys Acta. 1999 Dec 6;1473(1):9-20.
Title: The alpha1-6-fucosyltransferase gene and its biological significance.
Author: Miyoshi, E|Noda, K|Yamaguchi, Y|Inoue, S|Ikeda, Y|Wang, W|Ko, J H|Uozumi, N|Li, W|Taniguchi, N
PMID: 10580126
Journal: Hokkaido Igaku Zasshi. 1999 May;74(3):173-88.
Title: [Analysis of transcript mutations due to transcriptional slippage in rat p53 tumor suppressor gene with the use of yeast functional assay].
Author: Ba, Y
PMID: 10422562
Journal: J Hepatol. 2000 Jan;32(1):92-9.
Title: A possible novel src-related tyrosine kinase in cancer cells of LEC rats that develop hepatocellular carcinoma.
Author: Masaki, T|Tokuda, M|Shiratori, Y|Shirai, M|Matsumoto, K|Nishioka, M|Omata, M
PMID: 10673072
Journal: Anat Rec. 2000 Apr 1;258(4):338-48.
Title: Storage of lipid droplets in and production of extracellular matrix by hepatic stellate cells (vitamin A-storing cells) in Long-Evans cinnamon-like colored (LEC) rats.
Author: Imai, K|Sato, M|Kojima, N|Miura, M|Sato, T|Sugiyama, T|Enomoto, K|Senoo, H
PMID: 10737852
Journal: Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2000 Jun;17(2):133-8.
Title: [Invasion behavior of hepatocellular carcinoma cells correlates with their rheological properties].
Author: Wu, Z|Luo, X|Wang, X|Zhang, G|Long, M|Cai, S
PMID: 12557764
Journal: Hepatol Res. 2001 Sep;21(1):27-39.
Title: Overexpression of cyclin E and cyclin-dependent kinase 2 is correlated with development of hepatocellular carcinomas.
Author: Kohzato, N|Dong, Y|Sui, L|Masaki, T|Nagahata, S|Nishioka, M|Konishi, R|Tokuda, M
PMID: 11470626
Journal: Cancer Detect Prev. 2004;28(6):385-91.
Title: Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis.
Author: Bartsch, Helmut|Nair, Jagadeesan
PMID: 15582261
Journal: Redox Rep. 2007;12(1):35-9.
Title: The LEC rat: a useful model for studying liver carcinogenesis related to oxidative stress and inflammation.
Author: Marquez, Adriana|Villa-Trevino, Saul|Gueraud, Francoise
PMID: 17263906
Journal: J Proteome Res. 2010 Oct 1;9(10):4888-96.
Title: Glycomic analyses of glycoproteins in bile and serum during rat hepatocarcinogenesis.
Author: Nakagawa, Tsutomu|Takeishi, Shunsaku|Kameyama, Akihiko|Yagi, Hirokazu|Yoshioka, Tomoko|Moriwaki, Kenta|Masuda, Tomomi|Matsumoto, Hitoshi|Kato, Koichi|Narimatsu, Hisashi|Taniguchi, Naoyuki|Miyoshi, Eiji
PMID: 20731380
Journal: Biomed Res. 2011 Apr;32(2):111-7.
Title: Sexual dimorphism in LEC rat liver: suppression of carbonic anhydrase III by copper accumulation during hepatocarcinogenesis.
Author: Kuhara, Makihiko|Wang, Jingshu|Flores, Maria Jolina|Qiao, Zhiwei|Koizumi, Yukio|Koyota, Souichi|Taniguchi, Naoyuki|Sugiyama, Toshihiro
PMID: 21551946
Journal: Mitochondrial DNA A DNA Mapp Seq Anal. 2016 May;27(3):1928-9.
Title: The complete mitochondrial genome of a chronic hepatitis associated liver cancer LEC rat strain.
Author: Zhang, Sihao|Jiang, Zhaoming|Zhang, Shuai|Xia, Mingfeng|Tian, Fang|Tian, Hu
PMID: 25329295
Journal: Cureus. 2017 Feb 23;9(2):e1049.
Title: Comparison of Knowledge and Attitudes Regarding Hepatitis B Among Healthcare Professionals in Pakistan.
Author: Ali, Asad|Khan, Sara|Malik, Saad M|Haris Iqbal, Muhammad|Aadil, Muhammad
PMID: 28367387
Journal: Ann Surg. 2017 Nov;266(5):765-771.
Title: Lymphangiogenic Gene Expression Is Associated With Lymph Node Recurrence and Poor Prognosis After Partial Hepatectomy for Colorectal Liver Metastasis.
Author: Vellinga, Thomas T|Kranenburg, Onno|Frenkel, Nicola|Ubink, Inge|Marvin, Dieuwke|Govaert, Klaas|van Schelven, Susanne|Hagendoorn, Jeroen|Borel Rinkes, Inne H
PMID: 28742689