Literatures

Primary Site >> Pancreatic Cancer

Gene >> BRAF

1.
Journal:	Am J Pathol. 2003 Oct;163(4):1255-60.
Title:	BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets.
Author:	Calhoun, Eric S\|Jones, Jessa B\|Ashfaq, Raheela\|Adsay, Volkan\|Baker, Suzanne J\|Valentine, Virginia\|Hempen, Paula M\|Hilgers, Werner\|Yeo, Charles J\|Hruban, Ralph H\|Kern, Scott E
PMID:	14507635

2.
Journal:	Cancer Lett. 2003 Sep 25;199(2):169-73.
Title:	BRAF and K-ras gene mutations in human pancreatic cancers.
Author:	Ishimura, Norihisa\|Yamasawa, Kunihiro\|Karim Rumi, Mohammad Azharul\|Kadowaki, Yasunori\|Ishihara, Shunji\|Amano, Yuji\|Nio, Yoshinori\|Higami, Tetsuya\|Kinoshita, Yoshikazu
PMID:	12969789

3.
Journal:	Pancreas. 2004 Oct;29(3):193-203.
Title:	Orthotopic transplantation models of pancreatic adenocarcinoma derived from cell lines and primary tumors and displaying varying metastatic activity.
Author:	Loukopoulos, Panayiotis\|Kanetaka, Kengo\|Takamura, Masaaki\|Shibata, Tatsuhiro\|Sakamoto, Michiie\|Hirohashi, Setsuo
PMID:	15367885

4.
Journal:	Endocr Relat Cancer. 2004 Dec;11(4):855-60.
Title:	BRAF and endocrine tumors: mutations are frequent in papillary thyroid carcinomas, rare in endocrine tumors of the gastrointestinal tract and not detected in other endocrine tumors.
Author:	Perren, A\|Schmid, S\|Locher, T\|Saremaslani, P\|Bonvin, C\|Heitz, P U\|Komminoth, P
PMID:	15613458

5.
Journal:	Drugs Today (Barc). 2005 Mar;41(3):193-203.
Title:	The genetics of susceptibility to cutaneous melanoma.
Author:	Newton Bishop, Julia A\|Bishop, D Timothy
PMID:	15883616

6.
Journal:	Best Pract Res Clin Gastroenterol. 2006 Apr;20(2):211-26.
Title:	Molecular pathogenesis of pancreatic cancer.
Author:	Maitra, Anirban\|Kern, Scott E\|Hruban, Ralph H
PMID:	16549325

7.
Journal:	Virchows Arch. 2006 Jun;448(6):788-96.
Title:	Molecular analysis of the EGFR-RAS-RAF pathway in pancreatic ductal adenocarcinomas: lack of mutations in the BRAF and EGFR genes.
Author:	Immervoll, Heike\|Hoem, Dag\|Kugarajh, Kalaiarasy\|Steine, Solrun J\|Molven, Anders
PMID:	16598499

8.
Journal:	Cancer Lett. 2007 May 8;249(2):242-8.
Title:	BRAF and KRAS gene mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/IPMC) of the pancreas.
Author:	Schonleben, Frank\|Qiu, Wanglong\|Bruckman, Karl C\|Ciau, Nancy T\|Li, Xiaojun\|Lauerman, Margaret H\|Frucht, Harold\|Chabot, John A\|Allendorf, John D\|Remotti, Helen E\|Su, Gloria H
PMID:	17097223

9.
Journal:	Diagn Cytopathol. 2007 Apr;35(4):218-24.
Title:	Molecular diagnostic testing as an adjunct to morphologic evaluation of pancreatic ductal system brushings: potential augmentation for diagnostic sensitivity.
Author:	Willmore-Payne, Carlynn\|Volmar, Keith E\|Huening, Michael A\|Holden, Joseph A\|Layfield, Lester J
PMID:	17351944

10.
Journal:	J Biol Chem. 2007 May 11;282(19):14048-55. Epub 2007 Mar 12.
Title:	Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.
Author:	Ji, Zhenyu\|Mei, Fang C\|Xie, Jingwu\|Cheng, Xiaodong
PMID:	17353198

11.
Journal:	Hum Mutat. 2008 Feb;29(2):284-8.
Title:	PIK3CA cancer mutations display gender and tissue specificity patterns.
Author:	Benvenuti, Silvia\|Frattini, Milo\|Arena, Sabrina\|Zanon, Carlo\|Cappelletti, Vera\|Coradini, Danila\|Daidone, Maria Grazia\|Pilotti, Silvana\|Pierotti, Marco A\|Bardelli, Alberto
PMID:	18022911

12.
Journal:	Digestion. 2008;78(1):60-5.
Title:	Histopathological features of patients with chronic pancreatitis due to mutations in the PRSS1 gene: evaluation of BRAF and KRAS2 mutations.
Author:	Felderbauer, Peter\|Stricker, Ingo\|Schnekenburger, Jurgen\|Bulut, Kerem\|Chromik, Ansgar M\|Belyaev, Orlin\|Muller, Christophe A\|Uhl, Waldemar\|Tannapfel, Andrea\|Schmidt, Wolfgang E
PMID:	18946221

13.
Journal:	Langenbecks Arch Surg. 2008 May;393(3):289-96.
Title:	PIK3CA, KRAS, and BRAF mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/C) of the pancreas.
Author:	Schonleben, Frank\|Qiu, Wanglong\|Remotti, Helen E\|Hohenberger, Werner\|Su, Gloria H
PMID:	18343945

14.
Journal:	Appl Immunohistochem Mol Morphol. 2009 Jan;17(1):31-9.
Title:	Histologic, immunohistochemical, and molecular classification of 52 IPMNs of the pancreas.
Author:	Chadwick, Barbara\|Willmore-Payne, Carlynn\|Tripp, Sheryl\|Layfield, Lester J\|Hirschowitz, Sharon\|Holden, Joseph
PMID:	18813127

15.
Journal:	Mol Cancer Ther. 2009 Apr;8(4):834-43.
Title:	KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer.
Author:	Yeh, Jen Jen\|Routh, Elizabeth D\|Rubinas, Tara\|Peacock, Janie\|Martin, Timothy D\|Shen, Xiang Jun\|Sandler, Robert S\|Kim, Hong Jin\|Keku, Temitope O\|Der, Channing J
PMID:	19372556

16.
Journal:	Am J Surg Pathol. 2009 Aug;33(8):1164-72.
Title:	Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms.
Author:	Yamaguchi, Hiroshi\|Shimizu, Michio\|Ban, Shinichi\|Koyama, Isamu\|Hatori, Takashi\|Fujita, Izumi\|Yamamoto, Masakazu\|Kawamura, Shunji\|Kobayashi, Makio\|Ishida, Kazuyuki\|Morikawa, Takanori\|Motoi, Fuyuhiko\|Unno, Michiaki\|Kanno, Atsushi\|Satoh, Kennichi\|Shimosegawa
PMID:	19440145

17.
Journal:	PLoS One. 2009 Oct 14;4(10):e7464.
Title:	Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.
Author:	Soh, Junichi\|Okumura, Naoki\|Lockwood, William W\|Yamamoto, Hiromasa\|Shigematsu, Hisayuki\|Zhang, Wei\|Chari, Raj\|Shames, David S\|Tang, Ximing\|MacAulay, Calum\|Varella-Garcia, Marileila\|Vooder, Tonu\|Wistuba, Ignacio I\|Lam, Stephen\|Brekken, Rolf\|Toyooka, Shinic
PMID:	19826477

18.
Journal:	Pancreas. 2009 Oct;38(7):e200-6.
Title:	Resequencing analysis of the human tyrosine kinase gene family in pancreatic cancer.
Author:	Kubo, Takashi\|Kuroda, Yukie\|Kokubu, Akiko\|Hosoda, Fumie\|Arai, Yasuhito\|Hiraoka, Nobuyoshi\|Hirohashi, Setsuo\|Shibata, Tatsuhiro
PMID:	19893451

19.
Journal:	Mol Cancer Ther. 2011 Dec;10(12):2426-36.
Title:	GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway.
Author:	Wallin, Jeffrey J\|Edgar, Kyle A\|Guan, Jane\|Berry, Megan\|Prior, Wei Wei\|Lee, Leslie\|Lesnick, John D\|Lewis, Cristina\|Nonomiya, Jim\|Pang, Jodie\|Salphati, Laurent\|Olivero, Alan G\|Sutherlin, Daniel P\|O'Brien, Carol\|Spoerke, Jill M\|Patel, Sonal\|Lensun, Letitia\|
PMID:	21998291

20.
Journal:	Oncology. 2011;81(3-4):259-72.
Title:	Molecular pathogenesis of pancreatic cancer and clinical perspectives.
Author:	Matthaios, D\|Zarogoulidis, P\|Balgouranidou, I\|Chatzaki, E\|Kakolyris, S
PMID:	22116519

21.
Journal:	Am J Surg Pathol. 2011 Dec;35(12):1812-7.
Title:	Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.
Author:	Yamaguchi, Hiroshi\|Kuboki, Yuko\|Hatori, Takashi\|Yamamoto, Masakazu\|Shiratori, Keiko\|Kawamura, Shunji\|Kobayashi, Makio\|Shimizu, Michio\|Ban, Shinichi\|Koyama, Isamu\|Higashi, Morihiro\|Shin, Nobuhiro\|Ishida, Kazuyuki\|Morikawa, Takanori\|Motoi, Fuyuhiko\|Unno, Mi
PMID:	21945955

22.
Journal:	Nature. 2011 Jul 6;475(7354):106-9.
Title:	Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Author:	DeNicola, Gina M\|Karreth, Florian A\|Humpton, Timothy J\|Gopinathan, Aarthi\|Wei, Cong\|Frese, Kristopher\|Mangal, Dipti\|Yu, Kenneth H\|Yeo, Charles J\|Calhoun, Eric S\|Scrimieri, Francesca\|Winter, Jordan M\|Hruban, Ralph H\|Iacobuzio-Donahue, Christine\|Kern, Scott
PMID:	21734707

23.
Journal:	PLoS One. 2011;6(6):e20919.
Title:	Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.
Author:	Al-Ghamdi, Saleh\|Albasri, Abdulkader\|Cachat, Julien\|Ibrahem, Salih\|Muhammad, Belal A\|Jackson, Darryl\|Nateri, Abdolrahman S\|Kindle, Karin B\|Ilyas, Mohammad
PMID:	21698197

24.
Journal:	J Gastroenterol. 2012 Feb;47(2):203-13.
Title:	Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression.
Author:	Mohri, Dai\|Asaoka, Yoshinari\|Ijichi, Hideaki\|Miyabayashi, Koji\|Kudo, Yotaro\|Seto, Motoko\|Ohta, Miki\|Tada, Motohisa\|Tanaka, Yasuo\|Ikenoue, Tsuneo\|Tateishi, Keisuke\|Isayama, Hiroyuki\|Kanai, Fumihiko\|Fukushima, Noriyoshi\|Tada, Minoru\|Kawabe, Takao\|Omata, Mas
PMID:	22041919

25.
Journal:	Mol Cancer Res. 2012 Dec;10(12):1607-19.
Title:	Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.
Author:	Gysin, Stephan\|Paquette, Jesse\|McMahon, Martin
PMID:	22833572

26.
Journal:	Mol Cancer Res. 2012 Sep;10(9):1228-39. Epub 2012 Aug 7.
Title:	KRAS(G12D)- and BRAF(V600E)-induced transformation of murine pancreatic epithelial cells requires MEK/ERK-stimulated IGF1R signaling.
Author:	Appleman, Victoria A\|Ahronian, Leanne G\|Cai, JiuFeng\|Klimstra, David S\|Lewis, Brian C
PMID:	22871572

27.
Journal:	Clin J Gastroenterol. 2012 Dec;5(6):413-20.
Title:	Intraductal tubulopapillary neoplasm of the pancreas with somatic BRAF mutation.
Author:	Urata, Takahiro\|Naito, Yoshiki\|Nagamine, Michiko\|Izumi, Yoshihiro\|Tonaki, Ginga\|Iwasaki, Hajime\|Sasaki, Akiko\|Yamasaki, Akira\|Minami, Nobuhiro\|Yoshioka, Rituko\|Kitada, Hideki\|Takekuma, Yoshi\|Yokomizo, Hiroshi\|Fukuda, Seiji\|Yamaguchi, Hiroshi\|Kuboki, Yuko\|
PMID:	26181322

28.
Journal:	Cancer Res. 2013 Feb 1;73(3):1046-9.
Title:	Twenty-fourth annual Pezcoller symposium: Molecular basis for resistance to targeted agents.
Author:	Marais, Richard\|Sellers, William\|Livingston, David\|Mihich, Enrico
PMID:	23222297

29.
Journal:	Drugs. 2013 Jul;73(11):1245-54.
Title:	Trametinib: first global approval.
Author:	Wright, Cameron J M\|McCormack, Paul L
PMID:	23846731

30.
Journal:	Dig Liver Dis. 2014 Feb;46(2):182-6.
Title:	Sorafenib does not improve efficacy of chemotherapy in advanced pancreatic cancer: A GISCAD randomized phase II study.
Author:	Cascinu, Stefano\|Berardi, Rossana\|Sobrero, Alberto\|Bidoli, Paolo\|Labianca, Roberto\|Siena, Salvatore\|Ferrari, Daris\|Barni, Sandro\|Aitini, Enrico\|Zagonel, Vittorina\|Caprioni, Francesco\|Villa, Federica\|Mosconi, Stefania\|Faloppi, Luca\|Tonini, Giuseppe\|Boni, C
PMID:	24189171

31.
Journal:	Cancer Discov. 2014 Dec;4(12):1398-405.
Title:	Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes.
Author:	Chmielecki, Juliann\|Hutchinson, Katherine E\|Frampton, Garrett M\|Chalmers, Zachary R\|Johnson, Adrienne\|Shi, Chanjuan\|Elvin, Julia\|Ali, Siraj M\|Ross, Jeffrey S\|Basturk, Olca\|Balasubramanian, Sohail\|Lipson, Doron\|Yelensky, Roman\|Pao, William\|Miller, Vincent
PMID:	25266736

32.
Journal:	PLoS One. 2014 Jun 30;9(6):e100880.
Title:	Discovery of novel AKT inhibitors with enhanced anti-tumor effects in combination with the MEK inhibitor.
Author:	Dumble, Melissa\|Crouthamel, Ming-Chih\|Zhang, Shu-Yun\|Schaber, Michael\|Levy, Dana\|Robell, Kimberly\|Liu, Qi\|Figueroa, David J\|Minthorn, Elisabeth A\|Seefeld, Mark A\|Rouse, Meagan B\|Rabindran, Sridhar K\|Heerding, Dirk A\|Kumar, Rakesh
PMID:	24978597

33.
Journal:	J Pathol. 2014 Jul;233(3):217-27.
Title:	Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.
Author:	Amato, Eliana\|Molin, Marco Dal\|Mafficini, Andrea\|Yu, Jun\|Malleo, Giuseppe\|Rusev, Borislav\|Fassan, Matteo\|Antonello, Davide\|Sadakari, Yoshihiko\|Castelli, Paola\|Zamboni, Giuseppe\|Maitra, Anirban\|Salvia, Roberto\|Hruban, Ralph H\|Bassi, Claudio\|Capelli, Paola\|
PMID:	24604757

34.
Journal:	Biochem Biophys Res Commun. 2014 Feb 14;444(3):360-4.
Title:	IQGAP1 selectively interacts with K-Ras but not with H-Ras and modulates K-Ras function.
Author:	Matsunaga, Hironori\|Kubota, Kazuishi\|Inoue, Tatsuya\|Isono, Fujio\|Ando, Osamu
PMID:	24462863

35.
Journal:	Diagn Pathol. 2014 Jan 20;9:11.
Title:	Case report: Intraductal tubulopapillary neoplasm of the pancreas with unique clear cell phenotype.
Author:	Ahls, Maria Gabriele\|Niedergethmann, Marco\|Dinter, Dietmar\|Sauer, Christian\|Luttges, Jutta\|Post, Stefan\|Marx, Alexander\|Gaiser, Timo
PMID:	24443801

36.
Journal:	J Pathol. 2014 Mar;232(4):428-35.
Title:	Whole-exome sequencing of pancreatic neoplasms with acinar differentiation.
Author:	Jiao, Yuchen\|Yonescu, Raluca\|Offerhaus, G Johan A\|Klimstra, David S\|Maitra, Anirban\|Eshleman, James R\|Herman, James G\|Poh, Weijie\|Pelosof, Lorraine\|Wolfgang, Christopher L\|Vogelstein, Bert\|Kinzler, Kenneth W\|Hruban, Ralph H\|Papadopoulos, Nickolas\|Wood, La
PMID:	24293293

37.
Journal:	Cancer Genet. 2015 Sep;208(9):441-7.
Title:	Diagnostic yield of targeted next generation sequencing in various cancer types: an information-theoretic approach.
Author:	Hagemann, Ian S\|O'Neill, Patrick K\|Erill, Ivan\|Pfeifer, John D
PMID:	26227479

38.
Journal:	Nat Commun. 2015 Apr 9;6:6744.
Title:	Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.
Author:	Witkiewicz, Agnieszka K\|McMillan, Elizabeth A\|Balaji, Uthra\|Baek, GuemHee\|Lin, Wan-Chi\|Mansour, John\|Mollaee, Mehri\|Wagner, Kay-Uwe\|Koduru, Prasad\|Yopp, Adam\|Choti, Michael A\|Yeo, Charles J\|McCue, Peter\|White, Michael A\|Knudsen, Erik S
PMID:	25855536

39.
Journal:	Gastroenterology. 2015 Nov;149(6):1501-10.
Title:	A combination of molecular markers and clinical features improve the classification of pancreatic cysts.
Author:	Springer, Simeon\|Wang, Yuxuan\|Dal Molin, Marco\|Masica, David L\|Jiao, Yuchen\|Kinde, Isaac\|Blackford, Amanda\|Raman, Siva P\|Wolfgang, Christopher L\|Tomita, Tyler\|Niknafs, Noushin\|Douville, Christopher\|Ptak, Janine\|Dobbyn, Lisa\|Allen, Peter J\|Klimstra, David
PMID:	26253305

40.
Journal:	Int J Clin Exp Pathol. 2015 Aug 1;8(8):9672-80. eCollection 2015.
Title:	Multifocal intraductal tubulopapillary neoplasm of the pancreas with total pancreatectomy: report of a case and review of literature.
Author:	Kolby, David\|Thilen, Johan\|Andersson, Roland\|Sasor, Agata\|Ansari, Daniel
PMID:	26464736

41.
Journal:	Pathol Res Pract. 2015 Dec;211(12):1034-9.
Title:	A case of MUC5AC-positive intraductal neoplasm of the pancreas classified as an intraductal tubulopapillary neoplasm?
Author:	Muraki, Takashi\|Uehara, Takeshi\|Sano, Kenji\|Oota, Hiroyoshi\|Yoshizawa, Akihiko\|Asaka, Shiho\|Tateishi, Ayako\|Otsuki, Toshiaki\|Shingu, Kunihiko\|Matoba, Hisanori\|Kobayashi, Shota\|Ichimata, Shojiro\|Watanabe, Takayuki\|Itou, Tetsuya\|Tanaka, Eiji
PMID:	26586167

42.
Journal:	Mol Med Rep. 2015 Jan;11(1):277-82.
Title:	Identification of dysregulated pathways associated with pancreatic cancer by survival analysis.
Author:	Yuan, Qiong-Ying\|Gu, Yan-Ping\|Wang, Cong-Jun\|Zhang, Hui\|Wang, Xing-Peng
PMID:	25333741

43.
Journal:	Oncotarget. 2015 Mar 10;6(7):4553-61.
Title:	Molecular landscape of pancreatic cancer: implications for current clinical trials.
Author:	Heestand, Gregory M\|Kurzrock, Razelle
PMID:	25714017

44.
Journal:	Front Oncol. 2015 Feb 4;5:23.
Title:	Impacts of activation of the mitogen-activated protein kinase pathway in pancreatic cancer.
Author:	Furukawa, Toru
PMID:	25699241

45.
Journal:	Clin Cancer Res. 2015 Feb 15;21(4):730-8.
Title:	A phase Ib dose-escalation study of the oral pan-PI3K inhibitor buparlisib (BKM120) in combination with the oral MEK1/2 inhibitor trametinib (GSK1120212) in patients with selected advanced solid tumors.
Author:	Bedard, Philippe L\|Tabernero, Josep\|Janku, Filip\|Wainberg, Zev A\|Paz-Ares, Luis\|Vansteenkiste, Johan\|Van Cutsem, Eric\|Perez-Garcia, Jose\|Stathis, Anastasios\|Britten, Carolyn D\|Le, Ngocdiep\|Carter, Kirsten\|Demanse, David\|Csonka, Denes\|Peters, Malte\|Zubel,
PMID:	25500057

46.
Journal:	Oncotarget. 2015 Mar 10;6(7):4553-61.
Title:	Molecular landscape of pancreatic cancer: implications for current clinical trials.
Author:	Heestand, Gregory M\|Kurzrock, Razelle
PMID:	11051691

47.
Journal:	Oncotarget. 2015 Mar 30;6(9):7209-20.
Title:	Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.
Author:	Mitsuhashi, Kei\|Nosho, Katsuhiko\|Sukawa, Yasutaka\|Matsunaga, Yasutaka\|Ito, Miki\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Igarashi, Hisayoshi\|Naito, Takafumi\|Adachi, Yasushi\|Tachibana, Mami\|Tanuma, Tokuma\|Maguchi, Hiroyuki\|Shinohara, Toshiya\|Hasegawa, Tadashi\|I
PMID:	25797243

48.
Journal:	Med Oncol. 2016 Apr;33(4):32.
Title:	KRAS, BRAF, and PIK3CA mutations, and patient prognosis in 126 pancreatic cancers: pyrosequencing technology and literature review.
Author:	Zhou, Lei\|Baba, Yoshifumi\|Kitano, Yuki\|Miyake, Keisuke\|Zhang, Xiaobo\|Yamamura, Kensuke\|Kosumi, Keisuke\|Kaida, Takayoshi\|Arima, Kota\|Taki, Katsunobu\|Higashi, Takaaki\|Imai, Katsunori\|Hashimoto, Daisuke\|Yamashita, Yoichi\|Chikamoto, Akira\|Beppu, Toru\|Tan, Xia
PMID:	26927447

49.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2016 May;19(5):495-8.
Title:	[Clinicopathological characteristics of colorectal carcinoma in the elderly].
Author:	Tao, Kaixiong\|Gao, Jinbo\|Wang, Guobin
PMID:	27215512

50.
Journal:	Clin Ther. 2016 Jul;38(7):1622-35.
Title:	Genetic Testing in Pancreatic Ductal Adenocarcinoma: Implications for Prevention and Treatment.
Author:	Peters, Mary Linton B\|Tseng, Jennifer F\|Miksad, Rebecca A
PMID:	27041411

51.
Journal:	Cancer Discov. 2016 Mar;6(3):300-15.
Title:	Oncogenic BRAF Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120.
Author:	Chen, Shih-Hsun\|Zhang, Youyan\|Van Horn, Robert D\|Yin, Tinggui\|Buchanan, Sean\|Yadav, Vipin\|Mochalkin, Igor\|Wong, Swee Seong\|Yue, Yong Gang\|Huber, Lysiane\|Conti, Ilaria\|Henry, James R\|Starling, James J\|Plowman, Gregory D\|Peng, Sheng-Bin
PMID:	26732095

52.
Journal:	Hum Pathol. 2016 Feb;48:117-21.
Title:	Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia.
Author:	Ma, Changqing\|Gocke, Christopher D\|Hruban, Ralph H\|Belchis, Deborah A
PMID:	26626780

53.
Journal:	Hepatol Res. 2016 Jun;46(7):713-8.
Title:	Intraductal tubulopapillary neoplasm of the bile duct: A case report and review of the published work.
Author:	Nakagawa, Takashi\|Arisaka, Yoshifumi\|Ajiki, Tetsuo\|Fujikura, Kohei\|Masuda, Atsuhiro\|Takenaka, Mamoru\|Shiomi, Hideyuki\|Okabe, Yoshihiro\|Fukumoto, Takumi\|Ku, Yonson\|Azuma, Takeshi\|Zen, Yoh
PMID:	26459784

54.
Journal:	Int J Cancer. 2016 Feb 15;138(4):881-90.
Title:	The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
Author:	Ross, Jeffrey S\|Wang, Kai\|Chmielecki, Juliann\|Gay, Laurie\|Johnson, Adrienne\|Chudnovsky, Jacob\|Yelensky, Roman\|Lipson, Doron\|Ali, Siraj M\|Elvin, Julia A\|Vergilio, Jo-Anne\|Roels, Steven\|Miller, Vincent A\|Nakamura, Brooke N\|Gray, Adam\|Wong, Michael K\|Stephen
PMID:	26314551

55.
Journal:	Mol Clin Oncol. 2017 May;6(5):676-682.
Title:	Intraductal tubulopapillary neoplasm accompanied by invasive carcinoma of the pancreas: A case report and review of the literature.
Author:	Niu, Li\|Xu, Zhigao\|Liu, Huan\|Cao, Hong\|Yang, Guifang
PMID:	28529742

56.
Journal:	Postepy Dermatol Alergol. 2017 Oct;34(5):418-428.
Title:	The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors.
Author:	Owczarek, Witold\|Slowinska, Monika\|Lesiak, Aleksandra\|Ciazynska, Magdalena\|Maciag, Aldona\|Paluchowska, Elwira\|Marek-Jozefowicz, Luiza\|Czajkowski, Rafal
PMID:	29507555

57.
Journal:	Drug Des. 2017 Mar;6(1).
Title:	Synthesis, Biological Evaluation and Modeling Studies of New Pyrido[3,4-b]indole Derivatives as Broad-Spectrum Potent Anticancer Agents.
Author:	Patil, Shivaputra A\|Addo, James K\|Deokar, Hemantkumar\|Sun, Shan\|Wang, Jin\|Li, Wei\|Suttle, D Parker\|Wang, Wei\|Zhang, Ruiwen\|Buolamwini, John K
PMID:	29354330

58.
Journal:	Cell Biosci. 2017 Dec 16;7:71.
Title:	Hypoxic 3D in vitro culture models reveal distinct resistance processes to TKIs in renal cancer cells.
Author:	Bielecka, Zofia F\|Malinowska, Agata\|Brodaczewska, Klaudia K\|Klemba, Aleksandra\|Kieda, Claudine\|Krasowski, Pawel\|Grzesiuk, Elzbieta\|Piwowarski, Jan\|Czarnecka, Anna M\|Szczylik, Cezary
PMID:	29270287

59.
Journal:	World J Gastroenterol. 2017 Dec 7;23(45):7945-7951.
Title:	Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors.
Author:	Al-Hader, Ahmad\|Al-Rohil, Rami N\|Han, Haiyong\|Von Hoff, Daniel
PMID:	29259370

60.
Journal:	Oncol Lett. 2017 Nov;14(5):5980-5988.
Title:	Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome.
Author:	Lemstrova, Radmila\|Brynychova, Veronika\|Hughes, David J\|Hlavac, Viktor\|Dvorak, Pavel\|Doherty, Joanne E\|Murray, Helena A\|Crockard, Martin\|Oliverius, Martin\|Hlavsa, Jan\|Honsova, Eva\|Mazanec, Jan\|Kala, Zdenek\|Lovecek, Martin\|Havlik, Roman\|Ehrmann, Jiri\|Strou
PMID:	29113235

61.
Journal:	Cancer Lett. 2017 Aug 28;402:61-70.
Title:	A combinatorial strategy using YAP and pan-RAF inhibitors for treating KRAS-mutant pancreatic cancer.
Author:	Zhao, Xiao\|Wang, Xiuchao\|Fang, Lijun\|Lan, Chungen\|Zheng, Xiaowei\|Wang, Yongwei\|Zhang, Yinlong\|Han, Xuexiang\|Liu, Shaoli\|Cheng, Keman\|Zhao, Ying\|Shi, Jian\|Guo, Jiayi\|Hao, Jihui\|Ren, He\|Nie, Guangjun
PMID:	28576749

62.
Journal:	Mol Cancer Ther. 2017 Aug;16(8):1596-1609.
Title:	Identification of the Serine Biosynthesis Pathway as a Critical Component of BRAF Inhibitor Resistance of Melanoma, Pancreatic, and Non-Small Cell Lung Cancer Cells.
Author:	Ross, Kayleigh C\|Andrews, Andrew J\|Marion, Christopher D\|Yen, Timothy J\|Bhattacharjee, Vikram
PMID:	28500236

63.
Journal:	Cancer Treat Rev. 2017 May;56:28-35.
Title:	Unraveling molecular pathways of poorly differentiated neuroendocrine carcinomas of the gastroenteropancreatic system: A systematic review.
Author:	Girardi, Daniel M\|Silva, Andrea C B\|Rego, Juliana Florinda M\|Coudry, Renata A\|Riechelmann, Rachel P
PMID:	28456055

64.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

65.
Journal:	Cancer Lett. 2017 Jan 1;384:86-93.
Title:	Mutant allele specific imbalance in oncogenes with copy number alterations: Occurrence, mechanisms, and potential clinical implications.
Author:	Yu, Chih-Chieh\|Qiu, Wanglong\|Juang, Caroline S\|Mansukhani, Mahesh M\|Halmos, Balazs\|Su, Gloria H
PMID:	27725226

66.
Journal:	Mod Pathol. 2018 Jan;31(1):132-140.
Title:	A FISH assay efficiently screens for BRAF gene rearrangements in pancreatic acinar-type neoplasms.
Author:	Wang, Lu\|Basturk, Olca\|Wang, Jiajing\|Benayed, Ryma\|Middha, Sumit\|Zehir, Ahmet\|Linkov, Irina\|Rao, Mamta\|Aryeequaye, Ruth\|Cao, Long\|Chmielecki, Juliann\|Ross, Jeffrey\|Stephens, Philip J\|Adsay, Volkan\|Askan, Gokce\|Balci, Serdar\|Klimstra, David S
PMID:	28884748

67.
Journal:	Oncogene. 2018 Feb 8;37(6):821-832.
Title:	RAF inhibitor LY3009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and suppression of cyclin D1.
Author:	Chen, S-H\|Gong, X\|Zhang, Y\|Van Horn, R D\|Yin, T\|Huber, L\|Burke, T F\|Manro, J\|Iversen, P W\|Wu, W\|Bhagwat, S V\|Beckmann, R P\|Tiu, R V\|Buchanan, S G\|Peng, S-B
PMID:	29059158

68.
Journal:	Cancer Biomark. 2018 Feb 6;21(2):323-334.
Title:	Long-term survivors of pancreatic adenocarcinoma show low rates of genetic alterations in KRAS, TP53 and SMAD4.
Author:	Masetti, Michele\|Acquaviva, Giorgia\|Visani, Michela\|Tallini, Giovanni\|Fornelli, Adele\|Ragazzi, Moira\|Vasuri, Francesco\|Grifoni, Daniela\|Di Giacomo, Simone\|Fiorino, Sirio\|Lombardi, Raffaele\|Tuminati, David\|Ravaioli, Matteo\|Fabbri, Carlo\|Bacchi-Reggiani, Ma
PMID:	29103024

69.
Journal:	Arch Pathol Lab Med. 2018 Mar;142(3):420-423.
Title:	Intraductal Tubulopapillary Neoplasm of the Pancreas: An Overview.
Author:	Kim, Hyunsung\|Ro, Jae Y
PMID:	29494224

70.
Journal:	Z Gastroenterol. 2018 Apr;56(4):384-397.
Title:	[ASCO- and ESMO-update 2017 - highlights of the 53. meeting of the American Society of Clinical Oncology/ASCO 2017 and European Society for Medical Oncology/ESMO congress 2017].
Author:	Ettrich, Thomas J\|Ebert, Matthias\|Lorenzen, Sylvie\|Moehler, Markus\|Vogel, Arndt\|Witkowski, Lukas\|Seufferlein, Thomas\|Reinacher-Schick, Anke
PMID:	29642252

71.
Journal:	Oncotarget. 2018 Mar 27;9(23):16489-16500.
Title:	Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL.
Author:	Schorch, Bjorn\|Heni, Hannah\|Zahaf, Nour-Imene\|Brummer, Tilman\|Mione, Marina\|Schmidt, Gudula\|Papatheodorou, Panagiotis\|Aktories, Klaus
PMID:	29662661

72.
Journal:	Cancer Discov. 2018 Sep;8(9):1096-1111.
Title:	Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine.
Author:	Aguirre, Andrew J\|Nowak, Jonathan A\|Camarda, Nicholas D\|Moffitt, Richard A\|Ghazani, Arezou A\|Hazar-Rethinam, Mehlika\|Raghavan, Srivatsan\|Kim, Jaegil\|Brais, Lauren K\|Ragon, Dorisanne\|Welch, Marisa W\|Reilly, Emma\|McCabe, Devin\|Marini, Lori\|Anderka, Kristin\|
PMID:	29903880

73.
Journal:	Mol Cancer Ther. 2018 Jul 31. pii: 1535-7163.MCT-17-1142.
Title:	Concurrent HER or PI3K Inhibition Potentiates the Antitumor Effect of the ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models.
Author:	Jiang, Hongmei\|Xu, Mai\|Li, Lin\|Grierson, Patrick\|Dodhiawala, Paarth\|Highkin, Maureen\|Zhang, Daoxiang\|Li, Qiong\|Wang-Gillam, Andrea\|Lim, Kian-Huat
PMID:	30065098

74.
Journal:	Surg Case Rep. 2018 Aug 16;4(1):96.
Title:	Intrapancreatic recurrence of intraductal tubulopapillary neoplasm (ITPN) 16 years after the initial surgery for noninvasive ITPN: a case report.
Author:	Saeki, Kiyoshi\|Miyasaka, Yoshihiro\|Ohishi, Yoshihiro\|Yamamoto, Takeo\|Matsuda, Ryota\|Mochidome, Naoki\|Mori, Yasuhisa\|Nakata, Kohei\|Ohtsuka, Takao\|Ishigami, Kousei\|Minoda, Yosuke\|Koga, Yutaka\|Oda, Yoshinao\|Nakamura, Masafumi
PMID:	30116990

75.
Journal:	Medicine (Baltimore). 2018 Nov;97(44):e12940.
Title:	Laparoscopic pancreaticoduodenectomy for metastatic pancreatic melanoma: A case report.
Author:	Liu, Xueqing\|Feng, Feng\|Wang, Tianyang\|Qin, Jianzhang\|Yin, Xiangyan\|Meng, Guiqing\|Yan, Changqing\|Xing, Zhongqiang\|Duan, Jiayue\|Liu, Chen\|Liu, Jianhua
PMID:	30383642