Primary Site >> Stomach Cancer

Gene >> BECN1

Journal: Exp Cell Res. 2005 Jul 1;307(1):26-40.
Title: Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity.
Author: Furuya, Daisuke|Tsuji, Naoki|Yagihashi, Atsuhito|Watanabe, Naoki
PMID: 15922724
Journal: APMIS. 2007 Jun;115(6):750-6.
Title: Somatic mutations of BECN1, an autophagy-related gene, in human cancers.
Author: Lee, Jong Woo|Jeong, Eun Goo|Lee, Sung Hak|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 17550384
Journal: APMIS. 2007 Dec;115(12):1344-9.
Title: Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers.
Author: Ahn, Chang Hyeok|Jeong, Eun Goo|Lee, Jong Woo|Kim, Min Sung|Kim, Sung Hee|Kim, Sung Soo|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 18184403
Journal: Hum Pathol. 2008 Jul;39(7):1059-63.
Title: Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability.
Author: Kim, Min Sung|Jeong, Eun Goo|Ahn, Chang Hyeok|Kim, Sung Soo|Lee, Sug Hyung|Yoo, Nam Jin
PMID: 18495205
Journal: Oncol Rep. 2011 Jul;26(1):115-24.
Title: Autophagy is involved in anticancer effects of matrine on SGC-7901 human gastric cancer cells.
Author: Zhang, Junqiang|Li, Yumin|Chen, Xiaohui|Liu, Tao|Chen, Yingtai|He, Wenting|Zhang, Quanbao|Liu, Shiyuan
PMID: 21519796
Journal: Autophagy. 2011 Sep;7(9):966-78. Epub 2011 Sep 1.
Title: Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1alpha-mediated signaling.
Author: Wang, Kui|Liu, Rui|Li, Jingyi|Mao, Jiali|Lei, Yunlong|Wu, Jinhua|Zeng, Jun|Zhang, Tao|Wu, Hong|Chen, Lijuan|Huang, Canhua|Wei, Yuquan
PMID: 21610320
Journal: Oncol Rep. 2012 May;27(5):1481-7.
Title: Cytotoxic effect of evodiamine in SGC-7901 human gastric adenocarcinoma cells via simultaneous induction of apoptosis and autophagy.
Author: Rasul, Azhar|Yu, Bo|Zhong, Lili|Khan, Muhammad|Yang, Hong|Ma, Tonghui
PMID: 22367117
Journal: PLoS One. 2012;7(9):e45968.
Title: Beclin-1 expression is a significant predictor of survival in patients with lymph node-positive gastric cancer.
Author: Geng, Qi-Rong|Xu, Da-Zhi|He, Long-Jun|Lu, Jia-Bing|Zhou, Zhi-Wei|Zhan, You-Qing|Lu, Yue
PMID: 23029344
Journal: Toxicol Lett. 2012 Apr 5;210(1):78-86.
Title: E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells.
Author: Hu, Chen|Zou, Mei-Juan|Zhao, Li|Lu, Na|Sun, Ya-Jing|Gou, Shao-Hua|Xi, Tao|Guo, Qing-Long
PMID: 22322152
Journal: Autophagy. 2012 Mar;8(3):389-400.
Title: Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer.
Author: Zhou, Wei-Hua|Tang, Fang|Xu, Jie|Wu, Xing|Yang, Shao-Bing|Feng, Zhi-Ying|Ding, Yun-Gang|Wan, Xiang-Bo|Guan, Zhong|Li, Hai-Gang|Lin, Dong-Jun|Shao, Chun-Kui|Liu, Quentin
PMID: 22240664
Journal: J Surg Oncol. 2012 May;105(6):542-7.
Title: Decreased expression of Beclin 1 correlates with a metastatic phenotypic feature and adverse prognosis of gastric carcinomas.
Author: Chen, Ying-Bo|Hou, Jing-Hui|Feng, Xing-Yu|Chen, Shi|Zhou, Zhi-Wei|Zhang, Xiao-Shi|Cai, Mu-Yan
PMID: 22095667
Journal: Tumour Biol. 2013 Apr;34(2):1071-83.
Title: Beclin 1 expression is an independent prognostic factor for gastric carcinomas.
Author: Yu, Miao|Gou, Wen-feng|Zhao, Shuang|Xiao, Li-jun|Mao, Xiao-yun|Xing, Ya-nan|Takahashi, Hiroyuki|Takano, Yasuo|Zheng, Hua-chuan
PMID: 23334926
Journal: Tumour Biol. 2013 Dec;34(6):3303-7.
Title: The role of beclin-1 expression in patients with gastric cancer: a meta-analysis.
Author: Xia, Pu|Wang, Jin-Jin|Zhao, Bao-Bao|Song, Chang-Liang
PMID: 23943370
Journal: J Dairy Sci. 2013;96(12):7511-20.
Title: Bovine lactoferricin B induces apoptosis of human gastric cancer cell line AGS by inhibition of autophagy at a late stage.
Author: Pan, W-R|Chen, P-W|Chen, Y-L S|Hsu, H-C|Lin, C-C|Chen, W-J
PMID: 24140317
Journal: Oncol Rep. 2014 May;31(5):2321-7.
Title: Autophagy promotes the survival and development of tumors by participating in the formation of vasculogenic mimicry.
Author: Ding, Yun-Peng|Yang, Xiao-Dong|Wu, Yong|Xing, Chun-Gen
PMID: 24626574
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Jul;17(7):716-9.
Title: [Expression and significance of Beclin-1 in vasculogenic mimicry formation of gastric cancer].
Author: Ding, Yunpeng|Zhao, Kui|Wu, Yong|Xing, Chungen
PMID: 25070456
Journal: Cell Biol Int. 2014 Oct;38(10):1155-62.
Title: Bcl-2 down-regulation by small interfering RNA induces Beclin1-dependent autophagy in human SGC-7901 cells.
Author: Du, Yun|Ji, Xiaokun
PMID: 25044980
Journal: Oncol Lett. 2014 Aug;8(2):657-662.
Title: Effects of damage-regulated autophagy regulator gene on the SGC7901 human gastric cancer cell line.
Author: Zhu, Bao-Song|Zhao, Kui|Jia, Xin|Wu, Yong-You|Xing, Chun-Gen
PMID: 25013481
Journal: Tumour Biol. 2014 Aug;35(8):7317-26.
Title: The prognostic value of autophagy-related markers beclin-1 and microtubule-associated protein light chain 3B in cancers: a systematic review and meta-analysis.
Author: He, Yuyu|Zhao, Xianda|Subahan, Narishka Roz|Fan, Lifang|Gao, Jun|Chen, Honglei
PMID: 24838948
Journal: PLoS One. 2014 Apr 10;9(4):e94903.
Title: Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin.
Author: Zou, Jing|Yue, Fei|Li, Wenjiao|Song, Kun|Jiang, Xianhan|Yi, Jinglin|Liu, Leyuan
PMID: 24722279
Journal: Oncol Lett. 2014 Mar;7(3):635-640.
Title: Disturbance of autophagy-lysosome signaling molecule expression in human gastric adenocarcinoma.
Author: Wei, Shao-Hua|Li, Wei|Liu, Yang|Gao, DE-Kang|Pan, Jun|Gu, Chun-Wei|Wu, Hao-Rong
PMID: 24527069
Journal: PLoS One. 2014 Jan 9;9(1):e85116.
Title: The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway.
Author: Ji, Dongmei|Zhang, Zhe|Cheng, Lei|Chang, Jinjia|Wang, Shanshan|Zheng, Biqiang|Zheng, Rongliang|Sun, Zuojun|Wang, Chenchen|Zhang, Zhiqing|Liu, Rujiao|Zhang, Xiaowei|Liu, Xin|Wang, Xiaofeng|Li, Jin
PMID: 24416349
Journal: Pathol Res Pract. 2015 Apr;211(4):308-15.
Title: Autophagy is related to the hedgehog signaling pathway in human gastric adenocarcinoma: prognostic significance of Beclin-1 and Gli2 expression in human gastric adenocarcinoma.
Author: Won, Kyu Yeoun|Kim, Gou Young|Lim, Sung-Jig|Sung, Ji-Youn|Kim, Youn Wha|Park, Yong-Koo|Lee, Juhie|Choi, Hee Seung
PMID: 25512258
Journal: Cancer Lett. 2015 Mar 1;358(1):17-26.
Title: Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: involvement of the Akt-mTOR signaling pathway.
Author: Zhao, Zhi|Han, Fanghai|Yang, Shibin|Wu, Jianhai|Zhan, Wenhua
PMID: 25524555
Journal: Asian Pac J Cancer Prev. 2015;16(9):3907-12.
Title: Antitumor activity of chloroquine in combination with Cisplatin in human gastric cancer xenografts.
Author: Zhang, Hui-Qing|Fang, Nian|Liu, Xiao-Mei|Xiong, Shu-Ping|Liao, Yu-Qian|Jin, Wen-Jian|Song, Rong-Feng|Wan, Yi-Ye
PMID: 25987058
Journal: Int J Oncol. 2015 Sep;47(3):1061-9.
Title: Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells.
Author: Raha, Suchismita|Yumnam, Silvia|Hong, Gyeong Eun|Lee, Ho Jeong|Saralamma, Venu Venkatarame Gowda|Park, Hyeon-Soo|Heo, Jeong Doo|Lee, Sang Joon|Kim, Eun Hee|Kim, Jin-A|Kim, Gon Sup
PMID: 26201693
Journal: Tumour Biol. 2015 Jul 25.
Title: Fluorouracil induces autophagy-related gastric carcinoma cell death through Beclin-1 upregulation by miR-30 suppression.
Author: Yang, Chun|Pan, Yong
PMID: 26209295
Journal: Oncol Rep. 2016 Feb;35(2):649-58.
Title: Reduction of apoptosis by proanthocyanidin-induced autophagy in the human gastric cancer cell line MGC-803.
Author: Nie, Chao|Zhou, Jie|Qin, Xiaokang|Shi, Xianming|Zeng, Qingqi|Liu, Jia|Yan, Shihai|Zhang, Lei
PMID: 26572257
Journal: Zhong Yao Cai. 2016 May;39(5):1134-8.
Title: [Study on Mulberry Anthocyanins Induced Autophagy and Apoptosis of Human Gastric Cancer SGC-7901 Cell Autophagy].
Author: Zhang, Lei|Zhou, Jie|Luo, Jun|Wang, Qiong|Liu, Jia|Zeng, Qing-qi
PMID: 30133211
Journal: Dis Markers. 2016;2016:6869415.
Title: The Prognostic Role of SIRT1-Autophagy Axis in Gastric Cancer.
Author: Qiu, Guanglin|Li, Xuqi|Wei, Chao|Che, Xiangming|He, Shicai|Lu, Jing|Wang, Shufeng|Pang, Ke|Fan, Lin
PMID: 28070138
Journal: Am J Transl Res. 2016 Sep 15;8(9):3831-3847. eCollection 2016.
Title: Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer.
Author: Cao, Qing-Hua|Liu, Fang|Yang, Zu-Li|Fu, Xin-Hui|Yang, Zi-Huan|Liu, Quentin|Wang, Lei|Wan, Xiang-Bo|Fan, Xin-Juan
PMID: 27725863
Journal: Tumour Biol. 2016 Nov;37(11):15007-15017.
Title: Low expression of MAP1LC3B, associated with low Beclin-1, predicts lymph node metastasis and poor prognosis of gastric cancer.
Author: Yu, Shuangjin|Li, Guanghua|Wang, Zhao|Wang, Zhixiong|Chen, Chuangqi|Cai, Shirong|He, Yulong
PMID: 27655288
Journal: Eur J Pharmacol. 2016 Jun 15;781:164-72.
Title: DT-13, a saponin monomer of dwarf lilyturf tuber, induces autophagy and potentiates anti-cancer effect of nutrient deprivation.
Author: Li, Hongyang|Sun, Li|de Carvalho, Evandro Lopes|Li, Xinxin|Lv, Xiaodan|Khan, Ghulam Jilany|Semukunzi, Herve|Yuan, Shengtao|Lin, Sensen
PMID: 27079642
Journal: Cell Biol Int. 2016 Jul;40(7):770-8.
Title: Oleanolic acid induces autophagic death in human gastric cancer cells in vitro and in vivo.
Author: Nie, Hao|Wang, Yu|Qin, Yong|Gong, Xing-Guo
PMID: 27079177
Journal: Oncol Lett. 2016 Mar;11(3):2271-2277.
Title: Expression and clinical significance of Beclin-1 in gastric cancer tissues of various clinical stages.
Author: Fei, Bingyuan|Ji, Fujian|Chen, Xuebo|Liu, Zhuo|Li, Shuo|Mo, Zhanhao|Fang, Xuedong
PMID: 26998161
Journal: Anticancer Res. 2016 Jan;36(1):129-36.
Title: Clinicopathological Correlations of Autophagy-related Proteins LC3, Beclin 1 and p62 in Gastric Cancer.
Author: Masuda, G O|Yashiro, Masakazu|Kitayama, Kishu|Miki, Yuichiro|Kasashima, Hiroaki|Kinoshita, Haruhito|Morisaki, Tamami|Fukuoka, Tatshunari|Hasegawa, Tsuyoshi|Sakurai, Katsunobu|Toyokawa, Takahiro|Kubo, Naoshi|Tanaka, Hiroaki|Muguruma, Kazuya|Masaichi, Ohira
PMID: 26722036
Journal: Oncotarget. 2016 Aug 2;7(31):49322-49333.
Title: Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients.
Author: Szasz, A Marcell|Lanczky, Andras|Nagy, Adam|Forster, Susann|Hark, Kim|Green, Jeffrey E|Boussioutas, Alex|Busuttil, Rita|Szabo, Andras|Gyorffy, Balazs
PMID: 27384994
Journal: Tumour Biol. 2017 Jun;39(6):1010428317711952.
Title: Mild hyperthermia enhances sensitivity of gastric cancer cells to chemotherapy through reactive oxygen species-induced autophagic death.
Author: Ba, Ming-Chen|Long, Hui|Cui, Shu-Zhong|Gong, Yuan-Feng|Yan, Zhao-Fei|Wang, Shuai|Wu, Yin-Bing
PMID: 28639902
Journal: Oncotarget. 2017 May 20;8(56):95075-95082.
Title: Traditional Chinese medicine Ka-Sai-Ping suppresses the growths of gastric cancers via induction of autophagy.
Author: Zhu, Mo-Li|Lu, Jun-Xiu|Pan, Guo-Pin|Ping, Song|Zhao, Fan-Rong|Qi, Heng-Tian|Yu, Hai-Ya|Jian, Xu|Wan, Guang-Rui|Li, Peng
PMID: 29221112
Journal: Int J Oncol. 2017 Nov;51(5):1383-1394.
Title: Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo.
Author: Wei, Feng|Jiang, Xin|Gao, Hao-Yue|Gao, Shuo-Hui
PMID: 29048624
Journal: Zhonghua Zhong Liu Za Zhi. 2017 Jul 23;39(7):490-496.
Title: [Curcumin induces apoptosis and protective autophagy in human gastric cancer cells with different degree of differentiation].
Author: Li, W|Zhou, Y|Yang, J|Zhang, H H|Zhao, S L|Zhang, T|Huo, J|Zheng, P
PMID: 28728293
Journal: Oncol Rep. 2017 Jul;38(1):31-42.
Title: Synthetic lethal interaction of CDK inhibition and autophagy inhibition in human solid cancer cell lines.
Author: Okada, Yoshinari|Kato, Shunsuke|Sakamoto, Yasuhiro|Oishi, Takayuki|Ishioka, Chikashi
PMID: 28560460
Journal: Gene. 2017 Aug 30;626:48-53.
Title: Beclin1 antagonizes LAPTM4B-mediated EGFR overactivation in gastric cancer cells.
Author: Tian, Miao|Chen, Yu|Tian, Dan|Qiao, Xiaofang|Ma, Zhiming|Li, Jinlong
PMID: 28479384
Journal: Eur Rev Med Pharmacol Sci. 2017 Mar;21(5):1013-1019.
Title: TGF-beta1 promotes human gastric carcinoma SGC7901 cells invasion by inducing autophagy.
Author: Shen, J|Zhao, D-S|Li, M-Z
PMID: 28338195
Journal: Mol Ther. 2017 Apr 5;25(4):1027-1037.
Title: The microRNA-423-3p-Bim Axis Promotes Cancer Progression and Activates Oncogenic Autophagy in Gastric Cancer.
Author: Kong, Pengfei|Zhu, Xiaofeng|Geng, Qirong|Xia, Liangping|Sun, Xiaowei|Chen, Yingbo|Li, Wei|Zhou, Zhiwei|Zhan, Youqing|Xu, Dazhi
PMID: 28254439
Journal: Oncol Res. 2017 Sep 21;25(8):1399-1407.
Title: Gastrin Enhances Autophagy and Promotes Gastric Carcinoma Proliferation via Inducing AMPKalpha.
Author: Kun, Zhuang|Hanqing, Guo|Hailing, Tang|Yuan, Yan|Jun, Zhang|Lingxia, Zhang|Kun, Han|Xin, Zhang
PMID: 28059052
Journal: Mol Cell Biochem. 2017 Jan;424(1-2):173-183.
Title: Akt/AMPK/mTOR pathway was involved in the autophagy induced by vitamin E succinate in human gastric cancer SGC-7901 cells.
Author: Yu, Yang|Hou, Liying|Song, Huacui|Xu, Peixiang|Sun, Yue|Wu, Kun
PMID: 27796683
Journal: Biomed Pharmacother. 2018 Feb;98:709-718.
Title: Alpha, 2'-dihydroxy-4,4'-dimethoxydihydrochalcone inhibits cell proliferation, invasion, and migration in gastric cancer in part via autophagy.
Author: Wan, Boshun|Zhu, Junqiu|Chang, Qing|Zhou, Haihua|Shi, Zhan|Min, Li|Cai, YueJiao|Guan, Honggeng
PMID: 29306208
Journal: Oncol Lett. 2018 Jan;15(1):947-955.
Title: Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis.
Author: Huang, Xiaojun|Wang, Chaoqun|Sun, Jinmin|Luo, Jun|You, Jiangzhou|Liao, Linchuan|Li, Mingyuan
PMID: 29422968
Journal: Oncotarget. 2017 Dec 20;9(4):4886-4896.
Title: MiR-361-5p suppresses chemoresistance of gastric cancer cells by targeting FOXM1 via the PI3K/Akt/mTOR pathway.
Author: Tian, Lei|Zhao, Zhifeng|Xie, Ling|Zhu, JinPeng
PMID: 29435149
Journal: Mol Med Rep. 2018 May;17(5):6768-6776.
Title: Autophagy inhibition enhanced 5FUinduced cell death in human gastric carcinoma BGC823 cells.
Author: He, Xing-Xing|Huang, Chen-Kai|Xie, Bu-Shan
PMID: 29512733
Journal: Biomed Pharmacother. 2018 Aug;104:291-299.
Title: The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Author: Cai, Tiantian|Zhang, Chengzhe|Zhao, Ziming|Li, Siyi|Cai, Haobin|Chen, Xiaodong|Cai, Dake|Liu, Wei|Yan, Yan|Xie, Kaifeng|Pan, Huafeng|Zeng, Xiaohui
PMID: 29775897
Journal: Cell Death Dis. 2018 May 29;9(6):649.
Title: DSGOST regulates resistance via activation of autophagy in gastric cancer.
Author: Kim, Tae Woo|Lee, Seon Young|Kim, Mia|Cheon, Chunhoo|Jang, Bo-Hyoung|Shin, Yong Cheol|Ko, Seong-Gyu
PMID: 29844404
Journal: Cell Physiol Biochem. 2018;49(1):335-348.
Title: FOXO3 Inhibits Human Gastric Adenocarcinoma (AGS) Cell Growth by Promoting Autophagy in an Acidic Microenvironment.
Author: Gao, Yuan|Qi, Weiwei|Sun, Libin|Lv, Jing|Qiu, Wensheng|Liu, Shihai
PMID: 30138933
Journal: Int J Mol Sci. 2018 Sep 30;19(10). pii: ijms19102986.
Title: LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Author: Batool, Samana|Joseph, Thomson Patrick|Hussain, Mushraf|Vuai, Miza S|Khinsar, Kavish H|Din, Syed Riaz Ud|Padhiar, Arshad Ahmed|Zhong, Mintao|Ning, Anhong|Zhang, Wei|Cao, Jing|Huang, Min
PMID: 30274346