Primary Site >> Liver Cancer
Gene >> AXL
| 1. | |||||||||||
| Journal: | Genomics. 1998 Jun 15;50(3):331-40. | ||||||||||
| Title: | Parallel hybridization analysis of multiple protein kinase genes: identification of gene expression patterns characteristic of human hepatocellular carcinoma. | ||||||||||
| Author: | Tsou, A P|Wu, K M|Tsen, T Y|Chi, C W|Chiu, J H|Lui, W Y|Hu, C P|Chang, C|Chou, C K|Tsai, S F | ||||||||||
| PMID: | 9676427 | ||||||||||
| 2. | |||||||||||
| Journal: | Mol Carcinog. 2010 Oct;49(10):882-91. | ||||||||||
| Title: | Differential expression of Axl in hepatocellular carcinoma and correlation with tumor lymphatic metastasis. | ||||||||||
| Author: | He, Ling|Zhang, Jianing|Jiang, Lili|Jin, Changgong|Zhao, Yongfu|Yang, Guang|Jia, Li | ||||||||||
| PMID: | 20635370 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2011 Mar 10;30(10):1229-40. | ||||||||||
| Title: | AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma. | ||||||||||
| Author: | Xu, M Z|Chan, S W|Liu, A M|Wong, K F|Fan, S T|Chen, J|Poon, R T|Zender, L|Lowe, S W|Hong, W|Luk, J M | ||||||||||
| PMID: | 21076472 | ||||||||||
| 4. | |||||||||||
| Journal: | Biomed Pharmacother. 2012 Sep;66(6):454-8. | ||||||||||
| Title: | Genes responsible for the characteristics of primary cultured invasive phenotype hepatocellular carcinoma cells. | ||||||||||
| Author: | Lin, Zu-Yau|Chuang, Wan-Long | ||||||||||
| PMID: | 22681909 | ||||||||||
| 5. | |||||||||||
| Journal: | World J Gastroenterol. 2012 Oct 14;18(38):5369-76. | ||||||||||
| Title: | Axl glycosylation mediates tumor cell proliferation, invasion and lymphatic metastasis in murine hepatocellular carcinoma. | ||||||||||
| Author: | Li, Ji|Jia, Li|Ma, Zhen-Hai|Ma, Qiu-Hong|Yang, Xiao-Hong|Zhao, Yong-Fu | ||||||||||
| PMID: | 23082053 | ||||||||||
| 6. | |||||||||||
| Journal: | Adv Exp Med Biol. 2013;986:143-70. | ||||||||||
| Title: | Receptor tyrosine kinases: principles and functions in glioma invasion. | ||||||||||
| Author: | Nakada, Mitsutoshi|Kita, Daisuke|Teng, Lei|Pyko, Ilya V|Watanabe, Takuya|Hayashi, Yutaka|Hamada, Jun-ichiro | ||||||||||
| PMID: | 22879068 | ||||||||||
| 7. | |||||||||||
| Journal: | Am J Pathol. 2013 Dec;183(6):1719-1730. | ||||||||||
| Title: | Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure. | ||||||||||
| Author: | Hsu, Shu-Hao|Wang, Bo|Kutay, Huban|Bid, Hemant|Shreve, Julia|Zhang, Xiaoli|Costinean, Stefan|Bratasz, Anna|Houghton, Peter|Ghoshal, Kalpana | ||||||||||
| PMID: | 24113455 | ||||||||||
| 8. | |||||||||||
| Journal: | Carcinogenesis. 2014 Apr;35(4):769-75. | ||||||||||
| Title: | Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma. | ||||||||||
| Author: | Lee, Hsin-Jung|Jeng, Yung-Ming|Chen, Yu-Ling|Chung, Ling|Yuan, Ray-Hwang | ||||||||||
| PMID: | 24233839 | ||||||||||
| 9. | |||||||||||
| Journal: | Tumour Biol. 2014 Apr;35(4):3809-17. | ||||||||||
| Title: | Axl gene knockdown inhibits the metastasis properties of hepatocellular carcinoma via PI3K/Akt-PAK1 signal pathway. | ||||||||||
| Author: | Xu, Jingchao|Jia, Li|Ma, Hongye|Li, Yanping|Ma, Zhenhai|Zhao, Yongfu | ||||||||||
| PMID: | 24347489 | ||||||||||
| 10. | |||||||||||
| Journal: | Exp Eye Res. 2014 Jul;124:67-73. | ||||||||||
| Title: | The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation. | ||||||||||
| Author: | Brodowska, Katarzyna|Al-Moujahed, Ahmad|Marmalidou, Anna|Meyer Zu Horste, Melissa|Cichy, Joanna|Miller, Joan W|Gragoudas, Evangelos|Vavvas, Demetrios G | ||||||||||
| PMID: | 24837142 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncol Lett. 2015 Nov;10(5):2691-2698. | ||||||||||
| Title: | MicroRNA-34a-5p enhances sensitivity to chemotherapy by targeting AXL in hepatocellular carcinoma MHCC-97L cells. | ||||||||||
| Author: | Li, Xiao-Yun|Wen, Jing-Yun|Jia, Chang-Chang|Wang, Tian-Tian|Li, Xing|Dong, Min|Lin, Q U|Chen, Zhan-Hong|Ma, Xiao-Kun|Wei, L I|Lin, Ze-Xiao|Ruan, Dan-Yun|Chen, Jie|Wu, Dong-Hao|Liu, Wei|Tai, Yan|Xiong, Zhi-Yong|Wu, Xiang-Yuan|Zhang, Q I | ||||||||||
| PMID: | 26722228 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncol Rep. 2015 Dec;34(6):2987-96. | ||||||||||
| Title: | Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies. | ||||||||||
| Author: | Fujimori, Takayuki|Kato, Kiyohito|Fujihara, Shintaro|Iwama, Hisakazu|Yamashita, Takuma|Kobayashi, Kiyoyuki|Kamada, Hideki|Morishita, Asahiro|Kobara, Hideki|Mori, Hirohito|Okano, Keiichi|Suzuki, Yasuyuki|Masaki, Tsutomu | ||||||||||
| PMID: | 26398221 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Cancer. 2015 Jul 15;137(2):385-394. | ||||||||||
| Title: | Multicenter analysis of soluble Axl reveals diagnostic value for very early stage hepatocellular carcinoma. | ||||||||||
| Author: | Reichl, Patrick|Fang, Meng|Starlinger, Patrick|Staufer, Katharina|Nenutil, Rudolf|Muller, Petr|Greplova, Kristina|Valik, Dalibor|Dooley, Steven|Brostjan, Christine|Gruenberger, Thomas|Shen, Jiayun|Man, Kwan|Trauner, Michael|Yu, Jun|Gao, Chun Fang|Mikulits | ||||||||||
| PMID: | 25529751 | ||||||||||
| 14. | |||||||||||
| Journal: | Hepatology. 2015 Mar;61(3):759-61. | ||||||||||
| Title: | When good transforming growth factor-beta turns bad in hepatocellular carcinoma: Axl takes the stage. | ||||||||||
| Author: | Calvisi, Diego F | ||||||||||
| PMID: | 25429775 | ||||||||||
| 15. | |||||||||||
| Journal: | Hepatology. 2015 Mar;61(3):930-41. | ||||||||||
| Title: | Axl activates autocrine transforming growth factor-beta signaling in hepatocellular carcinoma. | ||||||||||
| Author: | Reichl, Patrick|Dengler, Mirko|van Zijl, Franziska|Huber, Heidemarie|Fuhrlinger, Gerhard|Reichel, Christian|Sieghart, Wolfgang|Peck-Radosavljevic, Markus|Grubinger, Markus|Mikulits, Wolfgang | ||||||||||
| PMID: | 25251599 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Oncol. 2016 Jan;48(1):358-66. | ||||||||||
| Title: | Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression. | ||||||||||
| Author: | Duan, Yan|Wong, Winnie|Chua, Sonja Courtney|Wee, Hwee Lin|Lim, Seng Gee|Chua, Boon Tin|Ho, Han Kiat | ||||||||||
| PMID: | 26573872 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2016 May 16;11(5):e0154767. | ||||||||||
| Title: | Axl Expression Stratifies Patients with Poor Prognosis after Hepatectomy for Hepatocellular Carcinoma. | ||||||||||
| Author: | Liu, Jian|Wang, Kui|Yan, Zhenlin|Xia, Yong|Li, Jun|Shi, Lehua|Zou, Qifei|Wan, Xuying|Jiao, Binghua|Wang, Hongyang|Wu, Mengchao|Zhang, Yongjie|Shen, Feng | ||||||||||
| PMID: | 27182739 | ||||||||||
| 18. | |||||||||||
| Journal: | Clin Cancer Res. 2017 May 15;23(10):2405-2413. | ||||||||||
| Title: | A Phase I/II Multicenter Study of Single-Agent Foretinib as First-Line Therapy in Patients with Advanced Hepatocellular Carcinoma. | ||||||||||
| Author: | Yau, Thomas C C|Lencioni, Riccardo|Sukeepaisarnjaroen, Wattana|Chao, Yee|Yen, Chia-Jui|Lausoontornsiri, Wirote|Chen, Pei-Jer|Sanpajit, Theeranun|Camp, Aaron|Cox, Donna S|Gagnon, Robert C|Liu, Yuan|Raffensperger, Kristen E|Kulkarni, Diptee A|Kallender, How | ||||||||||
| PMID: | 27821605 | ||||||||||
| 19. | |||||||||||
| Journal: | Sci Rep. 2017 Apr 4;7(1):641. | ||||||||||
| Title: | Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. | ||||||||||
| Author: | Ohshima, Keiichi|Hatakeyama, Keiichi|Nagashima, Takeshi|Watanabe, Yuko|Kanto, Kaori|Doi, Yuki|Ide, Tomomi|Shimoda, Yuji|Tanabe, Tomoe|Ohnami, Sumiko|Ohnami, Shumpei|Serizawa, Masakuni|Maruyama, Koji|Akiyama, Yasuto|Urakami, Kenichi|Kusuhara, Masatoshi|Moc | ||||||||||
| PMID: | 28377632 | ||||||||||
| 20. | |||||||||||
| Journal: | Ann Oncol. 2017 Mar 1;28(3):528-534. | ||||||||||
| Title: | Cabozantinib in hepatocellular carcinoma: results of a phase 2 placebo-controlled randomized discontinuation study. | ||||||||||
| Author: | Kelley, R K|Verslype, C|Cohn, A L|Yang, T-S|Su, W-C|Burris, H|Braiteh, F|Vogelzang, N|Spira, A|Foster, P|Lee, Y|Van Cutsem, E | ||||||||||
| PMID: | 28426123 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 18;8(16):26434-26447. | ||||||||||
| Title: | RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Wei|Jia, Wei-Dong|Hu, Bing|Pan, Yue-Yin | ||||||||||
| PMID: | 28460436 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2017 Jul 11;8(28):46234-46248. | ||||||||||
| Title: | Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis. | ||||||||||
| Author: | Dengler, Mirko|Staufer, Katharina|Huber, Heidemarie|Stauber, Rudolf|Bantel, Heike|Weiss, Karl Heinz|Starlinger, Patrick|Pock, Hannelore|Kloters-Plachky, Petra|Gotthardt, Daniel N|Rauch, Peter|Lackner, Carolin|Stift, Judith|Brostjan, Christine|Gruenberger, | ||||||||||
| PMID: | 28526812 | ||||||||||
| 23. | |||||||||||
| Journal: | Future Oncol. 2017 Jul 13. | ||||||||||
| Title: | Cabozantinib in the treatment of hepatocellular carcinoma. | ||||||||||
| Author: | B Peters, Mary Linton|Miksad, Rebecca A | ||||||||||
| PMID: | 28703624 | ||||||||||
| 24. | |||||||||||
| Journal: | Eur J Cancer. 2017 Nov;86:296-304. | ||||||||||
| Title: | Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours. | ||||||||||
| Author: | Schoffski, Patrick|Gordon, Michael|Smith, David C|Kurzrock, Razelle|Daud, Adil|Vogelzang, Nicholas J|Lee, Yihua|Scheffold, Christian|Shapiro, Geoffrey I | ||||||||||
| PMID: | 29059635 | ||||||||||
| 25. | |||||||||||
| Journal: | Cell Death Dis. 2017 Oct 26;8(10):e3135. | ||||||||||
| Title: | The non-invasive serum biomarker soluble Axl accurately detects advanced liver fibrosis and cirrhosis. | ||||||||||
| Author: | Staufer, Katharina|Dengler, Mirko|Huber, Heidemarie|Marculescu, Rodrig|Stauber, Rudolf|Lackner, Carolin|Dienes, Hans-Peter|Kivaranovic, Danijel|Schachner, Christian|Zeitlinger, Markus|Wulkersdorfer, Beatrix|Rauch, Peter|Prager, Gerhard|Trauner, Michael|Mi | ||||||||||
| PMID: | 29072690 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncol Lett. 2018 Feb;15(2):2441-2450. | ||||||||||
| Title: | Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells. | ||||||||||
| Author: | Scharf, Irene|Bierbaumer, Lisa|Huber, Heidemarie|Wittmann, Philipp|Haider, Christine|Pirker, Christine|Berger, Walter|Mikulits, Wolfgang | ||||||||||
| PMID: | 29434956 | ||||||||||
| 27. | |||||||||||
| Journal: | N Engl J Med. 2018 Jul 5;379(1):54-63. | ||||||||||
| Title: | Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma. | ||||||||||
| Author: | Abou-Alfa, Ghassan K|Meyer, Tim|Cheng, Ann-Lii|El-Khoueiry, Anthony B|Rimassa, Lorenza|Ryoo, Baek-Yeol|Cicin, Irfan|Merle, Philippe|Chen, YenHsun|Park, Joong-Won|Blanc, Jean-Frederic|Bolondi, Luigi|Klumpen, Heinz-Josef|Chan, Stephen L|Zagonel, Vittorina|P | ||||||||||
| PMID: | 29972759 | ||||||||||
| 28. | |||||||||||
| Journal: | Hepatology. 2018 Jul 16. | ||||||||||
| Title: | Transforming Growth Factor-beta and Axl Induce CXCL5 and Neutrophil Recruitment in Hepatocellular Carcinoma. | ||||||||||
| Author: | Haider, Christine|Hnat, Julia|Wagner, Roland|Huber, Heidemarie|Timelthaler, Gerald|Grubinger, Markus|Coulouarn, Cedric|Schreiner, Wolfgang|Schlangen, Karin|Sieghart, Wolfgang|Peck-Radosavljevic, Markus|Mikulits, Wolfgang | ||||||||||
| PMID: | 30014484 | ||||||||||