Primary Site >> Pancreatic Cancer

Gene >> ATRX

Journal: Mod Pathol. 2012 Jul;25(7):1033-9.
Title: Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors.
Author: de Wilde, Roeland F|Heaphy, Christopher M|Maitra, Anirban|Meeker, Alan K|Edil, Barish H|Wolfgang, Christopher L|Ellison, Trevor A|Schulick, Richard D|Molenaar, I Quintus|Valk, Gerlof D|Vriens, Menno R|Borel Rinkes, Inne H M|Offerhaus, G Johan A|Hruban, Ra
PMID: 22575867
Journal: Horm Cancer. 2013 Jun;4(3):165-75.
Title: Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors.
Author: Weisbrod, Allison B|Zhang, Lisa|Jain, Meenu|Barak, Stephanie|Quezado, Martha M|Kebebew, Electron
PMID: 23361940
Journal: Semin Oncol. 2013 Feb;40(1):37-44.
Title: The genetics of neuroendocrine tumors.
Author: Oberg, Kjell
PMID: 23391111
Journal: J Natl Cancer Inst. 2013 Jul 17;105(14):1005-17.
Title: Current understanding of the molecular biology of pancreatic neuroendocrine tumors.
Author: Zhang, Jianliang|Francois, Rony|Iyer, Renuka|Seshadri, Mukund|Zajac-Kaye, Maria|Hochwald, Steven N
PMID: 23840053
Journal: Gastroenterology. 2014 Feb;146(2):453-60.e5.
Title: Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors.
Author: Marinoni, Ilaria|Kurrer, Anja Schmitt|Vassella, Erik|Dettmer, Matthias|Rudolph, Thomas|Banz, Vanessa|Hunger, Fabio|Pasquinelli, Silvan|Speel, Ernst-Jan|Perren, Aurel
PMID: 24148618
Journal: Am J Clin Pathol. 2014 Feb;141(2):168-80.
Title: Molecular genetics of pancreatic neoplasms and their morphologic correlates: an update on recent advances and potential diagnostic applications.
Author: Reid, Michelle D|Saka, Burcu|Balci, Serdar|Goldblum, Andrew S|Adsay, N Volkan
PMID: 24436263
Journal: Oncol Rep. 2014 Dec;32(6):2753-9.
Title: Impact of the tumor microenvironment in predicting postoperative hepatic recurrence of pancreatic neuroendocrine tumors.
Author: Sato, Shoki|Tsuchikawa, Takahiro|Nakamura, Toru|Sato, Nagato|Tamoto, Eiji|Okamura, Keisuke|Shichinohe, Toshiaki|Hirano, Satoshi
PMID: 25310565
Journal: Am J Surg Pathol. 2015 Feb;39(2):236-44.
Title: Leiomyosarcoma with alternative lengthening of telomeres is associated with aggressive histologic features, loss of ATRX expression, and poor clinical outcome.
Author: Liau, Jau-Yu|Tsai, Jia-Huei|Jeng, Yung-Ming|Lee, Jen-Chieh|Hsu, Hung-Han|Yang, Ching-Yao
PMID: 25229770
Journal: J Mol Endocrinol. 2015 Apr;54(2):137-47.
Title: Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1.
Author: Vandamme, Timon|Peeters, Marc|Dogan, Fadime|Pauwels, Patrick|Van Assche, Elvire|Beyens, Matthias|Mortier, Geert|Vandeweyer, Geert|de Herder, Wouter|Van Camp, Guy|Hofland, Leo J|Op de Beeck, Ken
PMID: 25612765
Journal: J Hepatobiliary Pancreat Sci. 2015 Aug;22(8):594-601.
Title: Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendocrine tumors.
Author: Capurso, Gabriele|Archibugi, Livia|Delle Fave, Gianfranco
PMID: 25619712
Journal: Cancer Genet. 2015 Jul-Aug;208(7-8):374-81.
Title: Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.
Author: Boora, Ganesh K|Kanwar, Rahul|Kulkarni, Amit A|Pleticha, Josef|Ames, Matthew|Schroth, Gary|Beutler, Andreas S|Banck, Michaela S
PMID: 26087898
Journal: Scand J Gastroenterol. 2016 Aug;51(8):994-9.
Title: Study of clinicopathological features, hormone immunoexpression, and loss of ATRX and DAXX expression in pancreatic neuroendocrine tumors.
Author: Yadav, Rajni|Kakkar, Aanchal|Sharma, Atul|Malik, Prabhat Singh|Sharma, Mehar Chand
PMID: 27162024
Journal: Transl Gastroenterol Hepatol. 2016 Sep 23;1:73.
Title: Metastatic multiple endocrine neoplasia type 1: report of one case.
Author: Huang, Cheng|Zhu, Xiaodong|Han, Xu|Lou, Wenhui
PMID: 28138639
Journal: Endocr Pathol. 2016 Sep;27(3):200-4.
Title: New Genetics and Genomic Data on Pancreatic Neuroendocrine Tumors: Implications for Diagnosis, Treatment, and Targeted Therapies.
Author: Schmitt, Anja M|Marinoni, Ilaria|Blank, Annika|Perren, Aurel
PMID: 27456058
Journal: Am J Surg Pathol. 2016 Sep;40(9):1192-202.
Title: A Practical Approach to the Classification of WHO Grade 3 (G3) Well-differentiated Neuroendocrine Tumor (WD-NET) and Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) of the Pancreas.
Author: Tang, Laura H|Basturk, Olca|Sue, Jillian J|Klimstra, David S
PMID: 27259015
Journal: Pancreatology. 2016 May-Jun;16(3):411-5.
Title: Molecular alterations in sporadic pancreatic neuroendocrine microadenomas.
Author: Hadano, Atsuko|Hirabayashi, Kenichi|Yamada, Misuzu|Kawanishi, Aya|Takanashi, Yumi|Kawaguchi, Yoshiaki|Nakagohri, Toshio|Nakamura, Naoya|Mine, Tetsuya
PMID: 26905832
Journal: J Clin Endocrinol Metab. 2016 Feb;101(2):353-8.
Title: Neuroendocrine Tumor of the Pancreas as a Manifestation of Cowden Syndrome: A Case Report.
Author: Neychev, V|Sadowski, S M|Zhu, J|Allgaeuer, M|Kilian, K|Meltzer, P|Kebebew, E
PMID: 26678657
Journal: Int J Mol Sci. 2017 Jan 13;18(1). pii: ijms18010143.
Title: Pancreatic Neuroendocrine Neoplasms: Basic Biology, Current Treatment Strategies and Prospects for the Future.
Author: Ohmoto, Akihiro|Rokutan, Hirofumi|Yachida, Shinichi
PMID: 28098761
Journal: Endocr Relat Cancer. 2017 Mar;24(3):137-146.
Title: Hypo-methylation mediates chromosomal instability in pancreatic NET.
Author: Marinoni, I|Wiederkeher, A|Wiedmer, T|Pantasis, S|Di Domenico, A|Frank, R|Vassella, E|Schmitt, A|Perren, A
PMID: 28115389
Journal: Cancer Cytopathol. 2017 Jul;125(7):544-551.
Title: Alternative lengthening of telomeres and ATRX/DAXX loss can be reliably detected in FNAs of pancreatic neuroendocrine tumors.
Author: VandenBussche, Christopher J|Allison, Derek B|Graham, Mindy K|Charu, Vivek|Lennon, Anne Marie|Wolfgang, Christopher L|Hruban, Ralph H|Heaphy, Christopher M
PMID: 28371511
Journal: J Pathol Transl Med. 2017 Jul;51(4):388-395.
Title: Loss of Progesterone Receptor Expression Is an Early Tumorigenesis Event Associated with Tumor Progression and Shorter Survival in Pancreatic Neuroendocrine Tumor Patients.
Author: Kim, Sung Joo|An, Soyeon|Lee, Jae Hoon|Kim, Joo Young|Song, Ki-Byung|Hwang, Dae Wook|Kim, Song Cheol|Yu, Eunsil|Hong, Seung-Mo
PMID: 28597868
Journal: Oncotarget. 2017 Jun 28;8(55):93464-93475.
Title: Assessment of pancreatic neuroendocrine tumor cytologic genotype diversity to guide personalized medicine using a custom gastroenteropancreatic next-generation sequencing panel.
Author: Gleeson, Ferga C|Voss, Jesse S|Kipp, Benjamin R|Kerr, Sarah E|Van Arnam, John S|Mills, John R|Marcou, Cherisse A|Schneider, Amber R|Tu, Zheng Jin|Henry, Michael R|Levy, Michael J
PMID: 29212165
Journal: J Endocrinol. 2018 Mar;236(3):R161-R167.
Title: Genomic landscape of pancreatic neuroendocrine tumours: the International Cancer Genome Consortium.
Author: Mafficini, Andrea|Scarpa, Aldo
PMID: 29321190
Journal: Pancreas. 2018 Apr;47(4):502-510.
Title: Site-Specific Genomic Alterations in a Well-Differentiated Pancreatic Neuroendocrine Tumor With High-Grade Progression.
Author: Martin, David R|LaBauve, Elisa|Pomo, Joseph M|Chiu, Vi K|Hanson, Joshua A|Gullapalli, Rama R
PMID: 29521944
Journal: Hum Pathol. 2018 Jul;77:70-79.
Title: Pancreatic neuroendocrine carcinomas reveal a closer relationship to ductal adenocarcinomas than to neuroendocrine tumors G3.
Author: Konukiewitz, Bjorn|Jesinghaus, Moritz|Steiger, Katja|Schlitter, Anna Melissa|Kasajima, Atsuko|Sipos, Bence|Zamboni, Giuseppe|Weichert, Wilko|Pfarr, Nicole|Kloppel, Gunter
PMID: 29596894
Journal: Mol Cancer Res. 2018 Jun 14. pii: 1541-7786.MCR-18-0281.
Title: Daxx Functions Are p53-Independent In Vivo.
Author: Wasylishen, Amanda R|Estrella, Jeannelyn S|Pant, Vinod|Chau, Gilda P|Lozano, Guillermina
PMID: 29903771
Journal: Endocr Relat Cancer. 2018 Jul 18. pii: ERC-18-0120.
Title: Hotspot DAXX, PTCH2 and CYFIP2 mutations in pancreatic neuroendocrine neoplasms.
Author: Vandamme, Timon|Beyens, Matthias|Boons, Gitta|Schepers, Anne|Kamp, Kimberly|Biermann, Katharina|Pauwels, Patrick|de Herder, Wouter W|Hofland, Leo|Peeters, Marc|Van Camp, Guy|Op de Beeck, Ken
PMID: 30021865