Primary Site >> Liver Cancer
Gene >> ALDH2
| 1. | |||||||||||
| Journal: | Alcohol Alcohol Suppl. 1994;29(1):39-43. | ||||||||||
| Title: | Point mutation of aldehyde dehydrogenase-2 gene in mutant strains of Long-Evans rats. | ||||||||||
| Author: | Nakajima, M|Kato, J|Kohgo, Y|Takeichi, N|Niitsu, T | ||||||||||
| PMID: | 9063817 | ||||||||||
| 2. | |||||||||||
| Journal: | Alcohol Clin Exp Res. 1995 Dec;19(6):1414-9. | ||||||||||
| Title: | Hormonal and chemical influences on the expression of class 2 aldehyde dehydrogenases in rat H4IIEC3 and human HuH7 hepatoma cells. | ||||||||||
| Author: | Crabb, D W|Stewart, M J|Xiao, Q | ||||||||||
| PMID: | 8749803 | ||||||||||
| 3. | |||||||||||
| Journal: | J Epidemiol. 1998 Mar;8(1):1-5. | ||||||||||
| Title: | A case-control study on male hepatocellular carcinoma based on hospital and community controls. | ||||||||||
| Author: | Shibata, A|Fukuda, K|Nishiyori, A|Ogimoto, I|Sakata, R|Tanikawa, K | ||||||||||
| PMID: | 9575688 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Lett. 2000 Feb 28;149(1-2):69-76. | ||||||||||
| Title: | Relationship between alcohol drinking, ADH2 and ALDH2 genotypes, and risk for hepatocellular carcinoma in Japanese. | ||||||||||
| Author: | Takeshita, T|Yang, X|Inoue, Y|Sato, S|Morimoto, K | ||||||||||
| PMID: | 10737710 | ||||||||||
| 5. | |||||||||||
| Journal: | Jpn J Cancer Res. 2002 Dec;93(12):1287-92. | ||||||||||
| Title: | Hepatitis B and C viruses infection, lifestyle and genetic polymorphisms as risk factors for hepatocellular carcinoma in Haimen, China. | ||||||||||
| Author: | Yu, Shun-Zhang|Huang, Xin-En|Koide, Tsuneo|Cheng, Gang|Chen, Gong-Chao|Harada, Ken-ichi|Ueno, Yoshio|Sueoka, Eisaburo|Oda, Hideaki|Tashiro, Fumio|Mizokami, Masashi|Ohno, Tomoyoshi|Xiang, Jin|Tokudome, Shinkan | ||||||||||
| PMID: | 12495467 | ||||||||||
| 6. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2003 Jun;129(6):355-60. | ||||||||||
| Title: | Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma. | ||||||||||
| Author: | Munaka, Masahiro|Kohshi, Kiyotaka|Kawamoto, Toshihiro|Takasawa, Shin|Nagata, Naoki|Itoh, Hideaki|Oda, Susumu|Katoh, Takahiko | ||||||||||
| PMID: | 12759747 | ||||||||||
| 7. | |||||||||||
| Journal: | Scand J Gastroenterol. 2003 Aug;38(8):886-93. | ||||||||||
| Title: | Genetic polymorphisms of aldehyde dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the liver due to its polymorphism. | ||||||||||
| Author: | Kato, S|Tajiri, T|Matsukura, N|Matsuda, N|Taniai, N|Mamada, H|Yoshida, H|Kiyam, T|Naito, Z | ||||||||||
| PMID: | 12940444 | ||||||||||
| 8. | |||||||||||
| Journal: | Hepatol Res. 2004 Apr;28(4):177-183. | ||||||||||
| Title: | Hepatocellular carcinoma in heavy drinkers with negative markers for viral hepatitis. | ||||||||||
| Author: | Yamagishi, Yoshiyuki|Horie, Yoshinori|Kajihara, Mikio|Konishi, Masahiro|Ebinuma, Hirotoshi|Saito, Hidetsugu|Kato, Shinzo|Yokoyama, Akira|Maruyama, Katsuya|Ishii, Hiromasa | ||||||||||
| PMID: | 15040957 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Cancer. 2006 Mar 15;118(6):1501-7. | ||||||||||
| Title: | Influence of alcohol consumption and gene polymorphisms of ADH2 and ALDH2 on hepatocellular carcinoma in a Japanese population. | ||||||||||
| Author: | Sakamoto, Tatsuhiko|Hara, Megumi|Higaki, Yasuki|Ichiba, Masayoshi|Horita, Mikako|Mizuta, Toshihiko|Eguchi, Yuichiro|Yasutake, Tsutomu|Ozaki, Iwata|Yamamoto, Kyosuke|Onohara, Shingo|Kawazoe, Seiji|Shigematsu, Hirohisa|Koizumi, Shunzo|Tanaka, Keitaro | ||||||||||
| PMID: | 16187278 | ||||||||||
| 10. | |||||||||||
| Journal: | Toxicology. 2006 Mar 1;220(1):71-80. | ||||||||||
| Title: | Identification of human liver mitochondrial aldehyde dehydrogenase as a potential target for microcystin-LR. | ||||||||||
| Author: | Chen, Ting|Cui, Jun|Liang, Yan|Xin, Xiaoban|Owen Young, D|Chen, Chun|Shen, Pingping | ||||||||||
| PMID: | 16413648 | ||||||||||
| 11. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2008 Jan-Mar;9(1):31-5. | ||||||||||
| Title: | Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotypes, alcohol drinking and the risk of primary hepatocellular carcinoma in a Chinese population. | ||||||||||
| Author: | Ding, Jianhua|Li, Suping|Wu, Jianzhong|Gao, Changming|Zhou, Jiannong|Cao, Haixia|Su, Ping Su|Liu, Yanting|Zhou, Xuefu|Chang, Jun | ||||||||||
| PMID: | 18439068 | ||||||||||
| 12. | |||||||||||
| Journal: | Carcinogenesis. 2010 Apr;31(4):648-53. | ||||||||||
| Title: | Prevalence and persistence of chromosomal damage and susceptible genotypes of metabolic and DNA repair genes in Chinese vinyl chloride-exposed workers. | ||||||||||
| Author: | Ji, Fang|Wang, Wei|Xia, Zhao-Lin|Zheng, Ying-Jia|Qiu, Yu-Lan|Wu, Fen|Miao, Wen-Bin|Jin, Ru-Feng|Qian, Ji|Jin, Li|Zhu, Yi-Liang|Christiani, David C | ||||||||||
| PMID: | 20100738 | ||||||||||
| 13. | |||||||||||
| Journal: | Proteomics. 2010 Apr;10(8):1557-72. | ||||||||||
| Title: | The impact of miR-34a on protein output in hepatocellular carcinoma HepG2 cells. | ||||||||||
| Author: | Cheng, Jun|Zhou, Lin|Xie, Qin-Fen|Xie, Hai-Yang|Wei, Xu-Yong|Gao, Feng|Xing, Chun-Yang|Xu, Xiao|Li, Lan-Juan|Zheng, Shu-Sen | ||||||||||
| PMID: | 20186752 | ||||||||||
| 14. | |||||||||||
| Journal: | Wei Sheng Yan Jiu. 2010 Jan;39(1):42-5. | ||||||||||
| Title: | [Association between aldehyde dehydrogenase-2/cytochrome P450 2E1 genetic polymorphism and habit of alcohol drinking and the susceptibility of hepatocellular carcinoma]. | ||||||||||
| Author: | Ye, Xinping|Peng, Tao|Liu, Tangwei|Su, Zhixiong|Xiao, Kaiyin|Shang, Liming|Su, Ming|Li, Lequn | ||||||||||
| PMID: | 20364586 | ||||||||||
| 15. | |||||||||||
| Journal: | Chem Biol Interact. 2010 Dec 5;188(3):367-75. | ||||||||||
| Title: | Formation of acetaldehyde-derived DNA adducts due to alcohol exposure. | ||||||||||
| Author: | Yu, Hsu-Sheng|Oyama, Tsunehiro|Isse, Toyohi|Kitagawa, Kyoko|Pham, Thi-Thu-Phuong|Tanaka, Masayuki|Kawamoto, Toshihiro | ||||||||||
| PMID: | 20813101 | ||||||||||
| 16. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2012 Apr;27(4):797-804. | ||||||||||
| Title: | Genetic risk of hepatocellular carcinoma in patients with hepatitis C virus: a case control study. | ||||||||||
| Author: | Tomoda, Takeshi|Nouso, Kazuhiro|Sakai, Akiko|Ouchida, Mamoru|Kobayashi, Sayo|Miyahara, Koji|Onishi, Hideki|Nakamura, Shinichiro|Yamamoto, Kazuhide|Shimizu, Kenji | ||||||||||
| PMID: | 22004425 | ||||||||||
| 17. | |||||||||||
| Journal: | Free Radic Biol Med. 2012 Feb 15;52(4):735-46. | ||||||||||
| Title: | Aldehyde dehydrogenases and cell proliferation. | ||||||||||
| Author: | Muzio, G|Maggiora, M|Paiuzzi, E|Oraldi, M|Canuto, R A | ||||||||||
| PMID: | 22206977 | ||||||||||
| 18. | |||||||||||
| Journal: | Gastroenterol Nurs. 2014 Sep-Oct;37(5):327-36. | ||||||||||
| Title: | Asian flushing: genetic and sociocultural factors of alcoholism among East asians. | ||||||||||
| Author: | Lee, Haeok|Kim, Sun S|You, Kwang Soo|Park, Wanju|Yang, Jin Hyang|Kim, Minjin|Hayman, Laura L | ||||||||||
| PMID: | 25271825 | ||||||||||
| 19. | |||||||||||
| Journal: | PLoS One. 2014 Oct 22;9(10):e109235. | ||||||||||
| Title: | Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population. | ||||||||||
| Author: | Chang, Shen-Chih|Chang, Po-Yin|Butler, Brendan|Goldstein, Binh Y|Mu, Lina|Cai, Lin|You, Nai-Chieh Y|Baecker, Aileen|Yu, Shun-Zhang|Heber, David|Lu, Qing-Yi|Li, Liming|Greenland, Sander|Zhang, Zuo-Feng | ||||||||||
| PMID: | 25337902 | ||||||||||
| 20. | |||||||||||
| Journal: | Adv Exp Med Biol. 2015;815:41-58. | ||||||||||
| Title: | Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking. | ||||||||||
| Author: | Eriksson, C J Peter | ||||||||||
| PMID: | 25427900 | ||||||||||
| 21. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2015 Sep;30(9):1376-83. | ||||||||||
| Title: | Aldehyde dehydrogenase 2 polymorphism for development to hepatocellular carcinoma in East Asian alcoholic liver cirrhosis. | ||||||||||
| Author: | Abe, Hiroshi|Aida, Yuta|Seki, Nobuyoshi|Sugita, Tomonori|Tomita, Yoichi|Nagano, Tomohisa|Itagaki, Munenori|Sutoh, Satoshi|Nagatsuma, Keisuke|Itoh, Kyoko|Matsuura, Tomokazu|Aizawa, Yoshio | ||||||||||
| PMID: | 25778454 | ||||||||||
| 22. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9088-93. | ||||||||||
| Title: | ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis. | ||||||||||
| Author: | Jin, Shengfang|Chen, Jiang|Chen, Lizao|Histen, Gavin|Lin, Zhizhong|Gross, Stefan|Hixon, Jeffrey|Chen, Yue|Kung, Charles|Chen, Yiwei|Fu, Yufei|Lu, Yuxuan|Lin, Hui|Cai, Xiujun|Yang, Hua|Cairns, Rob A|Dorsch, Marion|Su, Shinsan M|Biller, Scott|Mak, Tak W|Can | ||||||||||
| PMID: | 26150517 | ||||||||||
| 23. | |||||||||||
| Journal: | Proteome Sci. 2017 Apr 20;15:7. | ||||||||||
| Title: | Proteomic profiling of HBV infected liver biopsies with different fibrotic stages. | ||||||||||
| Author: | Katrinli, Seyma|Ozdil, Kamil|Sahin, Abdurrahman|Ozturk, Oguzhan|Kir, Gozde|Baykal, Ahmet Tarik|Akgun, Emel|Sarac, Omer Sinan|Sokmen, Mehmet|Doganay, H Levent|Dinler Doganay, Gizem | ||||||||||
| PMID: | 28439208 | ||||||||||
| 24. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2016 Dec;31(12):1971-1977. | ||||||||||
| Title: | Risk and predictors of hepatocellular carcinoma for chronic hepatitis B patients with newly developed cirrhosis. | ||||||||||
| Author: | Chien, Justin|Liu, Jessica|Lee, Mei-Hsuan|Jen, Chin-Lan|Batrla-Utermann, Richard|Lu, Sheng-Nan|Wang, Li-Yu|You, San-Lin|Yang, Hwai-I|Chen, Chien-Jen | ||||||||||
| PMID: | 27118149 | ||||||||||
| 25. | |||||||||||
| Journal: | Sci Rep. 2016 Mar 17;6:23340. | ||||||||||
| Title: | Comparative Proteomics Analysis Reveals L-Arginine Activates Ethanol Degradation Pathways in HepG2 Cells. | ||||||||||
| Author: | Yan, Guokai|Lestari, Retno|Long, Baisheng|Fan, Qiwen|Wang, Zhichang|Guo, Xiaozhen|Yu, Jie|Hu, Jun|Yang, Xingya|Chen, Changqing|Liu, Lu|Li, Xiuzhi|Purnomoadi, Agung|Achmadi, Joelal|Yan, Xianghua | ||||||||||
| PMID: | 26983598 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2016 Apr;25(4):693-9. | ||||||||||
| Title: | Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma. | ||||||||||
| Author: | Liu, Jessica|Yang, Hwai-I|Lee, Mei-Hsuan|Jen, Chin-Lan|Hu, Hui-Han|Lu, Sheng-Nan|Wang, Li-Yu|You, San-Lin|Huang, Yen-Tsung|Chen, Chien-Jen | ||||||||||
| PMID: | 26827895 | ||||||||||
| 27. | |||||||||||
| Journal: | Life Sci. 2016 Feb 15;147:59-66. | ||||||||||
| Title: | ALDH2 gene polymorphism in different types of cancers and its clinical significance. | ||||||||||
| Author: | Li, Rui|Zhao, Zihan|Sun, Mingyang|Luo, Jiachi|Xiao, Yechen | ||||||||||
| PMID: | 26804999 | ||||||||||
| 28. | |||||||||||
| Journal: | Hepatology. 2017 May;65(5):1628-1644. | ||||||||||
| Title: | Aldehyde dehydrogenase-2 (ALDH2) opposes hepatocellular carcinoma progression by regulating AMP-activated protein kinase signaling in mice. | ||||||||||
| Author: | Hou, Guojun|Chen, Lei|Liu, Gang|Li, Liang|Yang, Yuan|Yan, He-Xin|Zhang, Hui-Lu|Tang, Jing|Yang, Ying Cheng|Lin, Ximeng|Chen, Xin|Luo, Gui Juan|Zhu, Yanjing|Tang, Shanhua|Zhang, Jin|Liu, Hui|Gu, Qingyang|Zhao, Ling-Hao|Li, Yixue|Liu, Lei|Zhou, Weiping|Wang | ||||||||||
| PMID: | 28027570 | ||||||||||
| 29. | |||||||||||
| Journal: | Pathol Res Pract. 2017 Apr;213(4):316-321. | ||||||||||
| Title: | Aberrant expression of cell cycle and material metabolism related genes contributes to hepatocellular carcinoma occurrence. | ||||||||||
| Author: | Yan, Hongxian|Li, Zhaohui|Shen, Quan|Wang, Qian|Tian, Jianguo|Jiang, Qingfeng|Gao, Linbo | ||||||||||
| PMID: | 28238542 | ||||||||||
| 30. | |||||||||||
| Journal: | J Biomed Sci. 2017 Mar 3;24(1):19. | ||||||||||
| Title: | ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective. | ||||||||||
| Author: | Chang, Jeffrey S|Hsiao, Jenn-Ren|Chen, Che-Hong | ||||||||||
| PMID: | 28253921 | ||||||||||
| 31. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2018 Mar 27;19(3):725-731. | ||||||||||
| Title: | ADH1B, ALDH2, GSTM1 and GSTT1 Gene Polymorphic Frequencies among Alcoholics and Controls in the Arcadian Population of Central India | ||||||||||
| Author: | Mansoori, Abdul Anvesh|Jain, Subodh Kumar | ||||||||||
| PMID: | 29582627 | ||||||||||
| 32. | |||||||||||
| Journal: | Genet Epidemiol. 2018 Jun;42(4):394-404. | ||||||||||
| Title: | A multiple mediator analysis approach to quantify the effects of the ADH1B and ALDH2 genes on hepatocellular carcinoma risk. | ||||||||||
| Author: | Shih, Stephannie|Huang, Yen-Tsung|Yang, Hwai-I | ||||||||||
| PMID: | 29600553 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Manag Res. 2018 May 4;10:1037-1050. | ||||||||||
| Title: | Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population. | ||||||||||
| Author: | Ye, Xinping|Wang, Xiangkun|Shang, Liming|Zhu, Guangzhi|Su, Hao|Han, Chuangye|Qin, Wei|Li, Guanghui|Peng, Tao | ||||||||||
| PMID: | 29765251 | ||||||||||
| 34. | |||||||||||
| Journal: | Exp Mol Pathol. 2018 Aug;105(1):63-70. | ||||||||||
| Title: | The murine hepatic sequelae of long-term ethanol consumption are sex-specific and exacerbated by Aldh1b1 loss. | ||||||||||
| Author: | Muller, Mike Freya|Kendall, Timothy James|Adams, David James|Zhou, Ying|Arends, Mark Johan | ||||||||||
| PMID: | 29859945 | ||||||||||
| 35. | |||||||||||
| Journal: | Cell Oncol (Dordr). 2018 Oct;41(5):527-539. | ||||||||||
| Title: | Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients. | ||||||||||
| Author: | Chen, Xin|Legrand, Arnaud J|Cunniffe, Siobhan|Hume, Samuel|Poletto, Mattia|Vaz, Bruno|Ramadan, Kristijan|Yao, Dengfu|Dianov, Grigory L | ||||||||||
| PMID: | 30088263 | ||||||||||