Primary Site >> Stomach Cancer

Gene >> ALDH2

Journal: Int J Cancer. 1996 Nov 4;68(3):313-6.
Title: Cancer screening of upper aerodigestive tract in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2 genotype.
Author: Yokoyama, A|Ohmori, T|Muramatsu, T|Higuchi, S|Yokoyama, T|Matsushita, S|Matsumoto, M|Maruyama, K|Hayashida, M|Ishii, H
PMID: 8903472
Journal: Carcinogenesis. 1998 Aug;19(8):1383-7.
Title: Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics.
Author: Yokoyama, A|Muramatsu, T|Ohmori, T|Yokoyama, T|Okuyama, K|Takahashi, H|Hasegawa, Y|Higuchi, S|Maruyama, K|Shirakura, K|Ishii, H
PMID: 9744533
Journal: Carcinogenesis. 2001 Mar;22(3):433-9.
Title: Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics.
Author: Yokoyama, A|Muramatsu, T|Omori, T|Yokoyama, T|Matsushita, S|Higuchi, S|Maruyama, K|Ishii, H
PMID: 11238183
Journal: World J Gastroenterol. 2005 Jun 7;11(21):3175-81.
Title: Kimchi and soybean pastes are risk factors of gastric cancer.
Author: Nan, Hong-Mei|Park, Jin-Woo|Song, Young-Jin|Yun, Hyo-Yung|Park, Joo-Seung|Hyun, Taisun|Youn, Sei-Jin|Kim, Yong-Dae|Kang, Jong-Won|Kim, Heon
PMID: 15929164
Journal: World J Gastroenterol. 2005 Jul 7;11(25):3834-41.
Title: Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer.
Author: Nan, Hong-Mei|Song, Young-Jin|Yun, Hyo-Yung|Park, Joo-Seung|Kim, Heon
PMID: 15991278
Journal: J Gastroenterol Hepatol. 2007 Feb;22(2):210-7.
Title: Helicobacter pylori, chronic atrophic gastritis, inactive aldehyde dehydrogenase-2, macrocytosis and multiple upper aerodigestive tract cancers and the risk for gastric cancer in alcoholic Japanese men.
Author: Yokoyama, Akira|Yokoyama, Tetsuji|Omori, Tai|Matsushita, Sachio|Mizukami, Takeshi|Takahashi, Hisao|Higuchi, Susumu|Maruyama, Katsuya|Ishii, Hiromasa|Hibi, Toshifumi
PMID: 17295873
Journal: Int J Cancer. 2007 Nov 1;121(9):2060-4.
Title: Genetic polymorphisms in alcohol metabolism, alcohol intake and the risk of stomach cancer in Warsaw, Poland.
Author: Zhang, Fang Fang|Hou, Lifang|Terry, Mary Beth|Lissowska, Jolanta|Morabia, Alfredo|Chen, Jinbo|Yeager, Meredith|Zatonski, Witold|Chanock, Stephen|Chow, Wong-Ho
PMID: 17631643
Journal: Helicobacter. 2008 Aug;13(4):245-55.
Title: Prevalence and risk factors of atrophic gastritis and intestinal metaplasia in a Korean population without significant gastroduodenal disease.
Author: Kim, Nayoung|Park, Young Soo|Cho, Sung-Il|Lee, Hye Seung|Choe, Gheeyoung|Kim, In Wook|Won, Yoo-Deok|Park, Ji Hyun|Kim, Joo Sung|Jung, Hyun Chae|Song, In Sung
PMID: 18665932
Journal: Mutat Res. 2009 Feb 19;673(1):74-7.
Title: Increased formation of gastric N(2)-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanol.
Author: Nagayoshi, Haruna|Matsumoto, Akiko|Nishi, Ryuhei|Kawamoto, Toshihiro|Ichiba, Masayoshi|Matsuda, Tomonari
PMID: 19101651
Journal: Curr Opin Genet Dev. 2010 Jun;20(3):210-7.
Title: Genetic predisposition to gastro-oesophageal cancer.
Author: Lao-Sirieix, Pierre|Caldas, Carlos|Fitzgerald, Rebecca C
PMID: 20347291
Journal: Asian Pac J Cancer Prev. 2010;11(4):1073-7.
Title: Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotypes, alcohol drinking and the risk for stomach cancer in Chinese males.
Author: Cao, Hai-Xia|Li, Su-Ping|Wu, Jian-Zhong|Gao, Chang-Ming|Su, Ping|Liu, Yan-Ting|Zhou, Jian-Nong|Ding, Jian-Hua
PMID: 21133627
Journal: J Dig Dis. 2011 Apr;12(2):51-9.
Title: Acetaldehyde and gastric cancer.
Author: Salaspuro, Mikko
PMID: 21401890
Journal: Int J Epidemiol. 2011 Aug;40(4):1047-55.
Title: Association between alcohol intake and risk for gastric cancer with regard to ALDH2 genotype in the Korean population.
Author: Shin, Cheol Min|Kim, Nayoung|Cho, Sung-Il|Kim, Joo Sung|Jung, Hyun Chae|Song, In Sung
PMID: 21507992
Journal: Cancer Lett. 2011 Dec 1;311(1):85-95.
Title: Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST).
Author: Balassiano, Karen|Lima, Sheila|Jenab, Mazda|Overvad, Kim|Tjonneland, Anne|Boutron-Ruault, Marie Christine|Clavel-Chapelon, Francoise|Canzian, Federico|Kaaks, Rudolf|Boeing, Heiner|Meidtner, Karina|Trichopoulou, Antonia|Laglou, Pagona|Vineis, Paolo|Panico,
PMID: 21831520
Journal: Carcinogenesis. 2012 Feb;33(2):361-7.
Title: Genetic variation in alcohol dehydrogenase (ADH1A, ADH1B, ADH1C, ADH7) and aldehyde dehydrogenase (ALDH2), alcohol consumption and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
Author: Duell, Eric J|Sala, Nuria|Travier, Noemie|Munoz, Xavier|Boutron-Ruault, Marie Christine|Clavel-Chapelon, Francoise|Barricarte, Aurelio|Arriola, Larraitz|Navarro, Carmen|Sanchez-Cantalejo, Emilio|Quiros, J Ramon|Krogh, Vittorio|Vineis, Paolo|Mattiello, Ama
PMID: 22144473
Journal: Gan To Kagaku Ryoho. 2012 Jan;39(1):8-12.
Title: [Present and future state of cancer screening for esophageal cancer and gastric cancer].
Author: Nakashima, Hirotaka|Nagahama, Ryuji|Yoshida, Misao
PMID: 22241346
Journal: Genet Mol Res. 2012 Sep 26;11(3):3497-504.
Title: Bioinformatics analysis with graph-based clustering to detect gastric cancer-related pathways.
Author: Liu, P|Wang, X|Hu, C H|Hu, T H
PMID: 23079843
Journal: Alcohol Alcohol. 2013 Mar-Apr;48(2):146-52.
Title: Trends in gastrectomy and ADH1B and ALDH2 genotypes in Japanese alcoholic men and their gene-gastrectomy, gene-gene and gene-age interactions for risk of alcoholism.
Author: Yokoyama, Akira|Yokoyama, Tetsuji|Matsui, Toshifumi|Mizukami, Takeshi|Kimura, Mitsuru|Matsushita, Sachio|Higuchi, Susumu|Maruyama, Katsuya
PMID: 23296215
Journal: Helicobacter. 2013 Sep;18 Suppl 1:34-8.
Title: Gastric cancer: epidemiologic aspects.
Author: Gonzalez, Carlos A|Sala, Nuria|Rokkas, Theodore
PMID: 24011243
Journal: Carcinogenesis. 2013 Jul;34(7):1510-5.
Title: The aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism interacts with alcohol drinking in the risk of stomach cancer.
Author: Matsuo, Keitaro|Oze, Isao|Hosono, Satoyo|Ito, Hidemi|Watanabe, Miki|Ishioka, Kuka|Ito, Seiji|Tajika, Masahiro|Yatabe, Yasushi|Niwa, Yasumasa|Yamao, Kenji|Nakamura, Shigeo|Tajima, Kazuo|Tanaka, Hideo
PMID: 23455379
Journal: PLoS One. 2014 Mar 14;9(3):e88779.
Title: ALDH2 and ADH1 genetic polymorphisms may contribute to the risk of gastric cancer: a meta-analysis.
Author: Wang, He-Ling|Zhou, Ping-Yi|Liu, Peng|Zhang, Yu
PMID: 24633362
Journal: Med Oncol. 2014 Oct;31(10):196.
Title: Screening of susceptibility genes and multi-gene risk analysis in gastric cancer.
Author: Shen, Xiao-bing|Wang, Jia|Li, Peng-fei|Ren, Xiao-feng|Yan, Xiao-luan|Wang, Fan
PMID: 25245011
Journal: PLoS One. 2014 Oct 22;9(10):e109235.
Title: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.
Author: Chang, Shen-Chih|Chang, Po-Yin|Butler, Brendan|Goldstein, Binh Y|Mu, Lina|Cai, Lin|You, Nai-Chieh Y|Baecker, Aileen|Yu, Shun-Zhang|Heber, David|Lu, Qing-Yi|Li, Liming|Greenland, Sander|Zhang, Zuo-Feng
PMID: 25337902
Journal: Cell Oncol (Dordr). 2014 Dec;37(6):455-61.
Title: Somatic mutations of amino acid metabolism-related genes in gastric and colorectal cancers and their regional heterogeneity--a short report.
Author: Oh, Hye Rim|An, Chang Hyeok|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 25450519
Journal: Adv Exp Med Biol. 2015;815:265-79.
Title: Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers.
Author: Yokoyama, Akira|Mizukami, Takeshi|Yokoyama, Tetsuji
PMID: 25427912
Journal: Carcinogenesis. 2015 Feb;36(2):223-31.
Title: Genetic polymorphisms of ADH1B, ADH1C and ALDH2, alcohol consumption, and the risk of gastric cancer: the Japan Public Health Center-based prospective study.
Author: Hidaka, Akihisa|Sasazuki, Shizuka|Matsuo, Keitaro|Ito, Hidemi|Sawada, Norie|Shimazu, Taichi|Yamaji, Taiki|Iwasaki, Motoki|Inoue, Manami|Tsugane, Shoichiro
PMID: 25524923
Journal: PLoS One. 2015 Apr 1;10(4):e0120397.
Title: Effects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration.
Author: Maejima, Ryuhei|Iijima, Katsunori|Kaihovaara, Pertti|Hatta, Waku|Koike, Tomoyuki|Imatani, Akira|Shimosegawa, Tooru|Salaspuro, Mikko
PMID: 25831092
Journal: Neoplasma. 2016;63(2):239-45.
Title: Discovery of signature genes in gastric cancer associated with prognosis.
Author: Zhao, X|Cai, H|Wang, X|Ma, L
PMID: 26774142
Journal: Genet Mol Res. 2016 Dec 19;15(4). pii: gmr-15-04-gmr.15048904.
Title: Analysis of ADH1B Arg47His, ALDH2 Glu487Lys, and CYP4502E1 polymorphisms in gastric cancer risk and interaction with environmental factors.
Author: Chen, Z H|Xian, J F|Luo, L P
PMID: 28002588
Journal: Oncotarget. 2017 Jan 24;8(4):6630-6641.
Title: Effects of alcohol consumption, ALDH2 rs671 polymorphism, and Helicobacter pylori infection on the gastric cancer risk in a Korean population.
Author: Yang, Sarah|Lee, Jeonghee|Choi, Il Ju|Kim, Young Woo|Ryu, Keun Won|Sung, Joohon|Kim, Jeongseon
PMID: 28036260
Journal: BMC Cancer. 2017 Nov 22;17(1):782.
Title: Polymorphisms in ADH1B and ALDH2 genes associated with the increased risk of gastric cancer in West Bengal, India.
Author: Ghosh, Sudakshina|Bankura, Biswabandhu|Ghosh, Soumee|Saha, Makhan Lal|Pattanayak, Arup Kumar|Ghatak, Souvik|Guha, Manalee|Nachimuthu, Senthil Kumar|Panda, Chinmoy Kumar|Maji, Suvendu|Chakraborty, Subrata|Maity, Biswanath|Das, Madhusudan
PMID: 29166882
Journal: Oncotarget. 2017 Oct 19;8(60):102401-102412.
Title: Association between ALDH2 rs671 G>A polymorphism and gastric cancer susceptibility in Eastern Asia.
Author: Jiang, You|Zhang, Jun|Wu, Yuee|Wang, Jian|Li, Liang
PMID: 29254255
Journal: Am J Ther. 2018 Feb 21.
Title: Effects of "Essential AD2" Supplement on Blood Acetaldehyde Levels in Individuals Who Have Aldehyde Dehydrogenase (ALDH2) Deficiency.
Author: Fujioka, Ken|Gordon, Spencer
PMID: 29509552
Journal: Gastric Cancer. 2018 Apr 3. pii: 10.1007/s10120-018-0823-0.
Title: Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replication and mediation analysis.
Author: Ishioka, Kuka|Masaoka, Hiroyuki|Ito, Hidemi|Oze, Isao|Ito, Seiji|Tajika, Masahiro|Shimizu, Yasuhiro|Niwa, Yasumasa|Nakamura, Shigeo|Matsuo, Keitaro
PMID: 29616362
Journal: J Hum Genet. 2018 Sep 10. pii: 10.1038/s10038-018-0501-4.
Title: Gastric cancer may share genetic predisposition with esophageal squamous cell carcinoma in Chinese populations.
Author: Yao, Linhua|Yu, Fei|Mao, Yingying|Wang, Tianpei|Qi, Qi|Ding, Hui|Wang, Jinchen|Ma, Hongxia|Dai, Juncheng|Zhang, Guoxin|Jin, Guangfu
PMID: 30202044