Primary Site >> Colorectal Cancer

Gene >> ALDH2

Journal: Alcohol Clin Exp Res. 1994 Oct;18(5):1256-60.
Title: Genetic polymorphism and activities of human colon alcohol and aldehyde dehydrogenases: no gender and age differences.
Author: Yin, S J|Liao, C S|Lee, Y C|Wu, C W|Jao, S W
PMID: 7847616
Journal: Jpn J Cancer Res. 1999 Jul;90(7):711-9.
Title: Genotype difference of aldehyde dehydrogenase 2 gene in alcohol drinkers influences the incidence of Japanese colorectal cancer patients.
Author: Murata, M|Tagawa, M|Watanabe, S|Kimura, H|Takeshita, T|Morimoto, K
PMID: 10470282
Journal: J Epidemiol. 2000 Sep;10(5):349-60.
Title: Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of colorectal cancer.
Author: Kiyohara, C
PMID: 11059519
Journal: Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):137S-143S.
Title: Alcohol and cancer.
Author: Seitz, H K|Matsuzaki, S|Yokoyama, A|Homann, N|Vakevainen, S|Wang, X D
PMID: 11391063
Journal: J Epidemiol. 2002 Mar;12(2):70-6.
Title: Aldehyde dehydrogenase 2 (ALDH2) genotype affects rectal cancer susceptibility due to alcohol consumption.
Author: Matsuo, Keitaro|Hamajima, Nobuyuki|Hirai, Takashi|Kato, Tomoyuki|Koike, Kouichi|Inoue, Manami|Takezaki, Toshiro|Tajima, Kazuo
PMID: 12033531
Journal: Cancer Epidemiol Biomarkers Prev. 2002 Nov;11(11):1332-52.
Title: Low-penetrance genes and their involvement in colorectal cancer susceptibility.
Author: de Jong, Mirjam M|Nolte, Ilja M|te Meerman, Gerard J|van der Graaf, Winette T A|de Vries, Elisabeth G E|Sijmons, Rolf H|Hofstra, Robert M W|Kleibeuker, Jan H
PMID: 12433710
Journal: J Nutr. 2004 Sep;134(9):2475S-2481S.
Title: Alcohol, one-carbon metabolism, and colorectal cancer: recent insights from molecular studies.
Author: Giovannucci, Edward
PMID: 15333745
Journal: Asian Pac J Cancer Prev. 2005 Jan-Mar;6(1):62-8.
Title: Relation of the CD36 gene A52C polymorphism to the risk of colorectal cancer among Japanese, with reference to with the aldehyde dehydrogenase 2 gene Glu487Lys polymorphism and drinking habit.
Author: Kuriki, Kiyonori|Hamajima, Nobuyuki|Chiba, Hitochi|Kanemitsu, Yukihide|Hirai, Takashi|Kato, Tomoyuki|Saito, Toshiko|Matsuo, Keitaro|Koike, Koichi|Tokudome, Shinkan|Tajima, Kazuo
PMID: 15780035
Journal: Pharmacogenet Genomics. 2005 Aug;15(8):535-46.
Title: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
Author: Landi, Stefano|Gemignani, Federica|Moreno, Victor|Gioia-Patricola, Lydie|Chabrier, Amelie|Guino, Elisabeth|Navarro, Matilde|de Oca, Javier|Capella, Gabriel|Canzian, Federico
PMID: 16006997
Journal: Nutr Cancer. 2005;53(1):42-50.
Title: Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan.
Author: Otani, Tetsuya|Iwasaki, Motoki|Hanaoka, Tomoyuki|Kobayashi, Minatsu|Ishihara, Junko|Natsukawa, Syusuke|Shaura, Kozo|Koizumi, Yoichi|Kasuga, Yoshio|Yoshimura, Kimio|Yoshida, Teruhiko|Tsugane, Shoichiro
PMID: 16351505
Journal: Carcinogenesis. 2006 May;27(5):1018-23. Epub 2005 Dec 6.
Title: A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan.
Author: Matsuo, Keitaro|Wakai, Kenji|Hirose, Kaoru|Ito, Hidemi|Saito, Toshiko|Suzuki, Takeshi|Kato, Tomoyuki|Hirai, Takashi|Kanemitsu, Yukihide|Hamajima, Hiroshi|Tajima, Kazuo
PMID: 16332725
Journal: Cancer Sci. 2007 Aug;98(8):1248-53. Epub 2007 May 22.
Title: Alcohol dehydrogenase and aldehyde dehydrogenase polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study.
Author: Yin, Guang|Kono, Suminori|Toyomura, Kengo|Moore, Malcolm A|Nagano, June|Mizoue, Tetsuya|Mibu, Ryuichi|Tanaka, Masao|Kakeji, Yoshihiro|Maehara, Yoshihiko|Okamura, Takeshi|Ikejiri, Koji|Futami, Kitaroh|Yasunami, Yohichi|Maekawa, Takafumi|Takenaka, Kenji|Ich
PMID: 17517051
Journal: Cancer Lett. 2008 Aug 8;266(2):171-85.
Title: Prohibitin identified by proteomic analysis of prostate biopsies distinguishes hyperplasia and cancer.
Author: Ummanni, Ramesh|Junker, Heike|Zimmermann, Uwe|Venz, Simone|Teller, Steffen|Giebel, Jurgen|Scharf, Christian|Woenckhaus, Christian|Dombrowski, Frank|Walther, Reinhard
PMID: 18384941
Journal: World J Gastroenterol. 2008 Aug 28;14(32):5078-83.
Title: Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males.
Author: Gao, Chang-Ming|Takezaki, Toshiro|Wu, Jian-Zhong|Zhang, Xiao-Mei|Cao, Hai-Xia|Ding, Jian-Hua|Liu, Yan-Ting|Li, Su-Ping|Cao, Jia|Matsuo, Keitaro|Hamajima, Nobuyuki|Tajima, Kazuo
PMID: 18763293
Journal: Ann Hum Genet. 2009 May;73(Pt 3):335-45.
Title: Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant.
Author: Li, Hui|Borinskaya, Svetlana|Yoshimura, Kimio|Kal'ina, Nina|Marusin, Andrey|Stepanov, Vadim A|Qin, Zhendong|Khaliq, Shagufta|Lee, Mi-Young|Yang, Yajun|Mohyuddin, Aisha|Gurwitz, David|Mehdi, Syed Qasim|Rogaev, Evgeny|Jin, Li|Yankovsky, Nikolay K|Kidd, Judi
PMID: 19456322
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2522-7.
Title: A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a southwestern Chinese population.
Author: Yang, Huan|Zhou, Yanhong|Zhou, Ziyuan|Liu, Jinyi|Yuan, Xiaoyan|Matsuo, Ketaro|Takezaki, Toshiro|Tajima, Kazuo|Cao, Jia
PMID: 19706845
Journal: Genes Nutr. 2010 Jun;5(2):121-8.
Title: Acetaldehyde as an underestimated risk factor for cancer development: role of genetics in ethanol metabolism.
Author: Seitz, Helmut K|Stickel, Felix
PMID: 19847467
Journal: Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S120-6.
Title: Association of aldehyde dehydrogenase 2 gene polymorphism with pancreatic cancer but not colon cancer.
Author: Miyasaka, Kyoko|Hosoya, Hiroko|Tanaka, Yasuo|Uegaki, Satoko|Kino, Kenji|Shimokata, Hiroshi|Kawanami, Takako|Funakoshi, Akihiro
PMID: 20590827
Journal: J Public Health (Oxf). 2011 Mar;33(1):71-9.
Title: The effects of screening on health behaviour: a summary of the results of randomized controlled trials.
Author: Deutekom, Marije|Vansenne, Fleur|McCaffery, Kirsten|Essink-Bot, Marie-Louise|Stronks, Karien|Bossuyt, Patrick M M
PMID: 20667898
Journal: Colorectal Dis. 2011 May;13(5):e71-8.
Title: Alcohol ingestion and colorectal neoplasia: a meta-analysis based on a Mendelian randomization approach.
Author: Wang, J|Wang, H|Chen, Y|Hao, P|Zhang, Y
PMID: 21114754
Journal: Alcohol. 2012 Feb;46(1):37-49.
Title: Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human large bowel: association of the functional polymorphisms of ADH and ALDH genes with hemorrhoids and colorectal cancer.
Author: Chiang, Chien-Ping|Jao, Shu-Wen|Lee, Shiao-Pieng|Chen, Pei-Chi|Chung, Chia-Chi|Lee, Shou-Lun|Nieh, Shin|Yin, Shih-Jiun
PMID: 21940137
Journal: Eur J Clin Nutr. 2012 Dec;66(12):1303-8.
Title: Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study.
Author: Ferrari, P|McKay, J D|Jenab, M|Brennan, P|Canzian, F|Vogel, U|Tjonneland, A|Overvad, K|Tolstrup, J S|Boutron-Ruault, M-C|Clavel-Chapelon, F|Morois, S|Kaaks, R|Boeing, H|Bergmann, M|Trichopoulou, A|Katsoulis, M|Trichopoulos, D|Krogh, V|Panico, S|Sacerdote,
PMID: 23149980
Journal: PLoS One. 2013 Nov 25;8(11):e80158.
Title: Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.
Author: Crous-Bou, Marta|Rennert, Gad|Cuadras, Daniel|Salazar, Ramon|Cordero, David|Saltz Rennert, Hedy|Lejbkowicz, Flavio|Kopelovich, Levy|Monroe Lipkin, Steven|Bernard Gruber, Stephen|Moreno, Victor
PMID: 24282520
Journal: Intern Med. 2013;52(24):2693-9.
Title: Meta-analysis of the ADH1B and ALDH2 polymorphisms and the risk of colorectal cancer in East Asians.
Author: Guo, Xu-Feng|Wang, Jun|Yu, Shi-Jie|Song, Jia|Ji, Meng-Yao|Zhang, Ji-Xiang|Cao, Zhuo|Wang, Jing|Dong, Wei-Guo
PMID: 24334570
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Oct;34(10):1013-7.
Title: [Role of alcohol-metabolizing enzymes gene polymorphisms and environmental exposure on colorectal cancer: a case-only study].
Author: Zhao, Hao|Li, Ting-ting|Yin, Jie-yun|Qin, Qin|Shi, Yun|Tian, Li-hong|Nie, Shao-fa|Wang, Xin|Liu, Li
PMID: 24377999
Journal: PLoS One. 2014 Feb 18;9(2):e88656.
Title: Meta-analysis of the aldehyde dehydrogenases-2 (ALDH2) Glu487Lys polymorphism and colorectal cancer risk.
Author: Zhao, Hua|Liu, Kui-Jie|Lei, Zhen-Dong|Lei, San-Lin|Tian, Yong-Quan
PMID: 24558407
Journal: Cell Oncol (Dordr). 2014 Dec;37(6):455-61.
Title: Somatic mutations of amino acid metabolism-related genes in gastric and colorectal cancers and their regional heterogeneity--a short report.
Author: Oh, Hye Rim|An, Chang Hyeok|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 25450519
Journal: Adv Exp Med Biol. 2015;815:281-94.
Title: Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers.
Author: Singh, S|Arcaroli, J|Thompson, D C|Messersmith, W|Vasiliou, V
PMID: 25427913
Journal: Pathol Oncol Res. 2015 Jul;21(3):727-33.
Title: A critical analysis of the relationship between aldehyde dehydrogenases-2 Glu487Lys polymorphism and colorectal cancer susceptibility.
Author: Chen, Bo|Hu, Kong-Wang|Zhang, Jia-Wei|Wei, Zhi-Jian|Meng, Xiang-Ling|Xiong, Mao-Ming
PMID: 25573590
Journal: Adv Exp Med Biol. 2015;815:265-79.
Title: Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers.
Author: Yokoyama, Akira|Mizukami, Takeshi|Yokoyama, Tetsuji
PMID: 25427912
Journal: Life Sci. 2016 Feb 15;147:59-66.
Title: ALDH2 gene polymorphism in different types of cancers and its clinical significance.
Author: Li, Rui|Zhao, Zihan|Sun, Mingyang|Luo, Jiachi|Xiao, Yechen
PMID: 26804999
Journal: Genet Mol Res. 2016 Aug 19;15(3). pii: gmr7872.
Title: Association between aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism and susceptibility to colorectal cancer: a meta-analysis.
Author: Zhao, S|Du, X M|Ma, S S|Wang, L M
PMID: 27706553
Journal: Genet Mol Res. 2016 Sep 23;15(3). pii: gmr8682.
Title: Association of ADH1B Arg47His and ALDH2 Glu487Lys polymorphisms with risk of colorectal cancer and their interaction with environmental factors in a Chinese population.
Author: Zhong, Q|Wu, R R|Zeng, Z M
PMID: 27706775
Journal: J Biomed Sci. 2017 Mar 3;24(1):19.
Title: ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective.
Author: Chang, Jeffrey S|Hsiao, Jenn-Ren|Chen, Che-Hong
PMID: 28253921
Journal: Int J Mol Sci. 2017 May 24;18(6). pii: ijms18061116.
Title: Molecular Basis of Alcohol-Related Gastric and Colon Cancer.
Author: Na, Hye-Kyung|Lee, Ja Young
PMID: 28538665
Journal: Br J Cancer. 2017 Nov 7;117(10):1537-1543.
Title: Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer.
Author: Matsumoto, Akiko|Arcaroli, John|Chen, Ying|Gasparetto, Maura|Neumeister, Veronique|Thompson, David C|Singh, Surendra|Smith, Clayton|Messersmith, Wells|Vasiliou, Vasilis
PMID: 28881356
Journal: Afr Health Sci. 2017 Mar;17(1):108-115.
Title: Association between ALDH2 Glu504Lys polymorphism and colorectal cancer risk: a meta-analysis.
Author: Xinhua, Jiang|Yanfei, Zhao
PMID: 29026383