Primary Site >> Liver Cancer

Gene >> AKR1C2

Journal: Cancer Res. 1999 Feb 1;59(3):607-14.
Title: Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
Author: Burczynski, M E|Lin, H K|Penning, T M
PMID: 9973208
Journal: Oncol Rep. 2003 Mar-Apr;10(2):271-6.
Title: Reduction of dihydrodiol dehydrogenase expression in resected hepatocellular carcinoma.
Author: Yang, Mei-Due|Wu, Cheng-Chung|Chiou, Shiow-Her|Chiu, Chang-Fang|Lin, Tze-Yi|Chiang, I-Ping|Chow, Kuan-Chih
PMID: 12579257
Journal: Hepatogastroenterology. 2005 Mar-Apr;52(62):567-70.
Title: Growth factor NUN increased AKR1C2 expression by activated CDK2 related RB signal transduction pathway in human liver cancer cell line.
Author: Lu, Dong-Dong
PMID: 15816479
Journal: Hepatogastroenterology. 2007 Sep;54(78):1731-5.
Title: Small interfering RNA (siRNA) inhibited human liver cancer cell line SMMC7721 proliferation and tumorigenesis.
Author: Dong-Dong, Lu
PMID: 18019706
Journal: Hepatogastroenterology. 2007 Oct-Nov;54(79):2088-91.
Title: AKR1C2 small interfering RNA (siRNA) inhibited beta-catenin expression and transcriptional activation in human liver cancer cell line QGY7701.
Author: Lu, Dong-Dong
PMID: 18251165
Journal: J Clin Pharmacol. 2008 Dec;48(12):1430-7.
Title: Bioequivalence studies of tibolone in premenopausal women and effects on expression of the tibolone-metabolizing enzyme AKR1C (aldo-keto reductase) family caused by estradiol.
Author: Kang, Keon W|Kim, Yoon G
PMID: 18832293
Journal: Oncol Res. 2014;22(4):203-11.
Title: AEG-1 Promotes Metastasis Through Downstream AKR1C2 and NF1 in Liver Cancer.
Author: Li, Cong|Wu, Xia|Zhang, Wei|Li, Jia|Liu, Huawei|Hao, Ming|Wang, Junsong|Zhang, Honghai|Yang, Gengxia|Hao, Meijun|Sheng, Shoupeng|Sun, Yu|Long, Jiang|Hu, Xiongbing|Zhang, Hanshuo|Hu, Caixia|Li, Li|Zheng, Jiasheng
PMID: 26351209
Journal: J Biomol Screen. 2016 Jan;21(1):101-7.
Title: High-Content Functional Screening of AEG-1 and AKR1C2 for the Promotion of Metastasis in Liver Cancer.
Author: Li, Cong|Wu, Xia|Zhang, Wei|Li, Jia|Liu, Huawei|Hao, Ming|Wang, Junsong|Zhang, Honghai|Yang, Gengxia|Hao, Meijun|Sheng, Shoupeng|Sun, Yu|Long, Jiang|Li, Juan|Zhuang, Fengfeng|Hu, Caixia|Li, Li|Zheng, Jiasheng
PMID: 26318406