Primary Site >> Pancreatic Cancer

Gene >> AGER

Journal: Hepatogastroenterology. 2001 Nov-Dec;48(42):1577-8.
Title: Differential expression of RAGE in human pancreatic carcinoma cells.
Author: Takada, M|Koizumi, T|Toyama, H|Suzuki, Y|Kuroda, Y
PMID: 11813576
Journal: Hepatogastroenterology. 2004 Jul-Aug;51(58):928-30.
Title: Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells.
Author: Takada, Moriatsu|Hirata, Kenro|Ajiki, Tetsuo|Suzuki, Yasuyuki|Kuroda, Yoshikazu
PMID: 15239215
Journal: Med Hypotheses. 2005;64(6):1208-10.
Title: Possible participation of advanced glycation end products in the pathogenesis of colorectal cancer in diabetic patients.
Author: Yamagishi, S|Nakamura, K|Inoue, H|Kikuchi, S|Takeuchi, M
PMID: 15823719
Journal: Clin Cancer Res. 2005 Aug 1;11(15):5356-64.
Title: S100P promotes pancreatic cancer growth, survival, and invasion.
Author: Arumugam, Thiruvengadam|Simeone, Diane M|Van Golen, Kenneth|Logsdon, Craig D
PMID: 16061848
Journal: J Natl Cancer Inst. 2006 Dec 20;98(24):1806-18.
Title: Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models.
Author: Arumugam, Thiruvengadam|Ramachandran, Vijaya|Logsdon, Craig D
PMID: 17179482
Journal: Curr Mol Med. 2007 Dec;7(8):711-24.
Title: RAGE: a single receptor for several ligands and different cellular responses: the case of certain S100 proteins.
Author: Donato, Rosario
PMID: 18331229
Journal: Cell Death Differ. 2010 Apr;17(4):666-76.
Title: The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival.
Author: Kang, R|Tang, D|Schapiro, N E|Livesey, K M|Farkas, A|Loughran, P|Bierhaus, A|Lotze, M T|Zeh, H J
PMID: 19834494
Journal: Scand J Gastroenterol. 2010;45(1):93-9.
Title: Serum leptin, but not adiponectin and receptor for advanced glycation end products, is able to distinguish autoimmune pancreatitis from both chronic pancreatitis and pancreatic neoplasms.
Author: Pezzilli, Raffaele|Barassi, Alessandra|Corsi, Massimiliano M|Morselli-Labate, Antonio M|Campana, Davide|Casadei, Riccardo|Santini, Donatella|Corinaldesi, Roberto|D'Eril, Gianvico Melzi
PMID: 19883273
Journal: Clin Biochem. 2010 Jul;43(10-11):882-6.
Title: Soluble receptor for advanced glycation end-products (sRAGE) and polymorphisms of RAGE and glyoxalase I genes in patients with pancreas cancer.
Author: Krechler, Tomas|Jachymova, Marie|Mestek, Oto|Zak, Ales|Zima, Tomas|Kalousova, Marta
PMID: 20398646
Journal: Antioxid Redox Signal. 2011 Oct 15;15(8):2175-84.
Title: The Receptor for Advanced Glycation End-products (RAGE) protects pancreatic tumor cells against oxidative injury.
Author: Kang, Rui|Tang, Daolin|Livesey, Kristen M|Schapiro, Nicole E|Lotze, Michael T|Zeh, Herbert J 3rd
PMID: 21126167
Journal: Cancer Res. 2011 May 15;71(10):3582-9.
Title: Evidence that serum levels of the soluble receptor for advanced glycation end products are inversely associated with pancreatic cancer risk: a prospective study.
Author: Jiao, Li|Weinstein, Stephanie J|Albanes, Demetrius|Taylor, Philip R|Graubard, Barry I|Virtamo, Jarmo|Stolzenberg-Solomon, Rachael Z
PMID: 21540233
Journal: Autophagy. 2011 Apr;7(4):442-4. Epub 2011 Apr 1.
Title: RAGE regulates autophagy and apoptosis following oxidative injury.
Author: Kang, Rui|Tang, Daolin|Lotze, Michael T|Zeh, Herbert J 3rd
PMID: 21317562
Journal: Autophagy. 2011 Jan;7(1):91-3.
Title: Apoptosis to autophagy switch triggered by the MHC class III-encoded receptor for advanced glycation endproducts (RAGE).
Author: Kang, Rui|Tang, Daolin|Loze, Michael T|Zeh, Herbert J
PMID: 20978368
Journal: J Gastrointest Surg. 2012 Jan;16(1):104-12; discussion 112.
Title: RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer.
Author: DiNorcia, Joseph|Lee, Minna K|Moroziewicz, Dorota N|Winner, Megan|Suman, Paritosh|Bao, Fei|Remotti, Helen E|Zou, Yu Shan|Yan, Shi Fang|Qiu, Wanglong|Su, Gloria H|Schmidt, Ann Marie|Allendorf, John D
PMID: 22052106
Journal: Cancer Epidemiol Biomarkers Prev. 2012 Apr;21(4):619-28.
Title: The associations of advanced glycation end products and its soluble receptor with pancreatic cancer risk: a case-control study within the prospective EPIC Cohort.
Author: Grote, Verena A|Nieters, Alexandra|Kaaks, Rudolf|Tjonneland, Anne|Roswall, Nina|Overvad, Kim|Nielsen, Michael R Skjelbo|Clavel-Chapelon, Francoise|Boutron-Ruault, Marie Christine|Racine, Antoine|Teucher, Birgit|Lukanova, Annekatrin|Boeing, Heiner|Drogan,
PMID: 22301828
Journal: Proc Natl Acad Sci U S A. 2012 May 1;109(18):7031-6.
Title: The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia.
Author: Kang, Rui|Loux, Tara|Tang, Daolin|Schapiro, Nicole E|Vernon, Philip|Livesey, Kristen M|Krasinskas, Alyssa|Lotze, Michael T|Zeh, Herbert J 3rd
PMID: 22509024
Journal: Clin Cancer Res. 2012 Aug 15;18(16):4356-64.
Title: S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis.
Author: Arumugam, Thiruvengadam|Ramachandran, Vijaya|Gomez, Sobeyda B|Schmidt, Ann M|Logsdon, Craig D
PMID: 22718861
Journal: Autophagy. 2012 Jun;8(6):989-91.
Title: AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway.
Author: Kang, Rui|Tang, Daolin|Lotze, Michael T|Zeh, Herbert J 3rd
PMID: 22722139
Journal: Am J Cancer Res. 2012;2(4):383-96. Epub 2012 Jun 28.
Title: Autophagy in pancreatic cancer pathogenesis and treatment.
Author: Kang, Rui|Tang, Daolin
PMID: 22860230
Journal: Horm Metab Res. 2013 May;45(5):387-90.
Title: Metformin inhibits advanced glycation end products (AGEs)-induced growth and VEGF expression in MCF-7 breast cancer cells by suppressing AGEs receptor expression via AMP-activated protein kinase.
Author: Ishibashi, Y|Matsui, T|Takeuchi, M|Yamagishi, S
PMID: 23225247
Journal: BMC Syst Biol. 2013 Oct 16;7 Suppl 3:S5.
Title: Analysis of intercellular signal transduction in the tumor microenvironment.
Author: Gong, Haijun
PMID: 24555417
Journal: Mol Cancer Ther. 2013 May;12(5):654-62.
Title: Designing and developing S100P inhibitor 5-methyl cromolyn for pancreatic cancer therapy.
Author: Arumugam, Thiruvengadam|Ramachandran, Vijaya|Sun, Duoli|Peng, Zhenghong|Pal, Ashutosh|Maxwell, David S|Bornmann, William G|Logsdon, Craig D
PMID: 23303403
Journal: PLoS One. 2013 Sep 4;8(9):e72480.
Title: Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody.
Author: Hernandez, Jose Luis|Padilla, Laura|Dakhel, Sheila|Coll, Toni|Hervas, Rosa|Adan, Jaume|Masa, Marc|Mitjans, Francesc|Martinez, Josep Maria|Coma, Silvia|Rodriguez, Laura|Noe, Veronique|Ciudad, Carlos J|Blasco, Francesc|Messeguer, Ramon
PMID: 24023743
Journal: Oncogene. 2014 Jan 30;33(5):567-77.
Title: The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics.
Author: Kang, R|Tang, D|Schapiro, N E|Loux, T|Livesey, K M|Billiar, T R|Wang, H|Van Houten, B|Lotze, M T|Zeh, H J
PMID: 23318458
Journal: Int J Mol Med. 2014 Apr;33(4):769-76.
Title: S100 family signaling network and related proteins in pancreatic cancer (Review).
Author: Ji, Yi-Fei|Huang, Hua|Jiang, Feng|Ni, Run-Zhou|Xiao, Ming-Bing
PMID: 24481067
Journal: Cell Death Dis. 2014 Oct 23;5:e1480.
Title: RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer.
Author: Kang, R|Hou, W|Zhang, Q|Chen, R|Lee, Y J|Bartlett, D L|Lotze, M T|Tang, D|Zeh, H J
PMID: 25341034
Journal: Int J Mol Epidemiol Genet. 2014 Oct 22;5(3):152-63. eCollection 2014.
Title: Determinants of concentrations of N(epsilon)-carboxymethyl-lysine and soluble receptor for advanced glycation end products and their associations with risk of pancreatic cancer.
Author: Duan, Zhigang|Chen, Guoqing|Chen, Liang|Stolzenberg-Solomon, Rachael|Weinstein, Stephanie J|Mannisto, Satu|White, Donna L|Albanes, Demetrius|Jiao, Li
PMID: 25379135
Journal: Biochim Biophys Acta. 2015 Dec;1852(12):2706-11.
Title: The role of S100 proteins and their receptor RAGE in pancreatic cancer.
Author: Leclerc, Estelle|Vetter, Stefan W
PMID: 26435083
Journal: Cancer Gene Ther. 2015 Jun;22(6):326-34.
Title: The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.
Author: Boone, B A|Orlichenko, L|Schapiro, N E|Loughran, P|Gianfrate, G C|Ellis, J T|Singhi, A D|Kang, R|Tang, D|Lotze, M T|Zeh, H J
PMID: 25908451
Journal: J Biomed Sci. 2015 Apr 17;22:28.
Title: Novel adjuvants from seaweed impede autophagy signaling in therapy-resistant residual pancreatic cancer.
Author: Aravindan, Sheeja|Ramraj, Satish Kumar|Somasundaram, Somasundaram T|Aravindan, Natarajan
PMID: 25898131
Journal: Cancer Lett. 2015 Jan 28;356(2 Pt A):281-8.
Title: Epidemiological-molecular evidence of metabolic reprogramming on proliferation, autophagy and cell signaling in pancreas cancer.
Author: Soreide, Kjetil|Sund, Malin
PMID: 24704294
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2017 Jan;48(1):46-51.
Title: [Effects of RAGE on Cell Proliferation and Tumor Growth in Pancreatic Cancer].
Author: Chen, Wei-Wei|Guo, Qiang|Zhang, Zhao-da|Hu, Wei-Ming
PMID: 28612557
Journal: Biochem Biophys Res Commun. 2017 Nov 4;493(1):592-597.
Title: RAGE maintains high levels of NFkappaB and oncogenic Kras activity in pancreatic cancer.
Author: Azizan, Nancy|Suter, Melissa A|Liu, Yan|Logsdon, Craig D
PMID: 28867179
Journal: Semin Cancer Biol. 2018 Apr;49:37-43.
Title: The receptor for advanced glycation end products: A fuel to pancreatic cancer.
Author: Shahab, Uzma|Ahmad, Mohd Kaleem|Mahdi, Abbas Ali|Waseem, Mohd|Arif, Binish|Moinuddin|Ahmad, Saheem
PMID: 28811077
Journal: PLoS One. 2018 Mar 12;13(3):e0192821.
Title: RAGE-specific single chain Fv for PET imaging of pancreatic cancer.
Author: Kim, Hye-Yeong|Wang, Xiaolei|Kang, Rui|Tang, Daolin|Boone, Brian A|Zeh, Herbert J 3rd|Lotze, Michael T|Edwards, W Barry
PMID: 29529089
Journal: J Pathol. 2018 Jun;245(2):197-208.
Title: The advanced glycation end-product N() -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention.
Author: Menini, Stefano|Iacobini, Carla|de Latouliere, Luisa|Manni, Isabella|Ionta, Vittoria|Blasetti Fantauzzi, Claudia|Pesce, Carlo|Cappello, Paola|Novelli, Francesco|Piaggio, Giulia|Pugliese, Giuseppe
PMID: 29533466
Journal: Cancer Med. 2018 May;7(5):2180-2191.
Title: A prospective study of soluble receptor for advanced glycation end products and adipokines in association with pancreatic cancer in postmenopausal women.
Author: White, Donna L|Hoogeveen, Ron C|Chen, Liang|Richardson, Peter|Ravishankar, Milan|Shah, Preksha|Tinker, Lesley|Rohan, Thomas|Whitsel, Eric A|El-Serag, Hashem B|Jiao, Li
PMID: 29573228
Journal: BMC Cancer. 2018 Jun 22;18(1):678.
Title: Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps.
Author: Boone, Brian A|Murthy, Pranav|Miller-Ocuin, Jennifer|Doerfler, W Reed|Ellis, Jarrod T|Liang, Xiaoyan|Ross, Mark A|Wallace, Callen T|Sperry, Jason L|Lotze, Michael T|Neal, Matthew D|Zeh, Herbert J 3rd
PMID: 29929491
Journal: Invest New Drugs. 2018 Jul 12. pii: 10.1007/s10637-018-0635-4.
Title: The marine natural product Scalarin inhibits the receptor for advanced glycation end products (RAGE) and autophagy in the PANC-1 and MIA PaCa-2 pancreatic cancer cell lines.
Author: Guzman, Esther Amalia|Pitts, Tara Peterson|Diaz, Maria Cristina|Wright, Amy Elizabeth
PMID: 29998364