Primary Site >> Pancreatic Cancer

Gene >> ABCB1

Journal: Int J Oncol. 1994 Dec;5(6):1285-92.
Title: Multidrug-resistance gene (mdr1) expression in human tumor xenografts.
Author: Abe, Y|Nakamura, M|Ohnishi, Y|Inaba, M|Ueyama, Y|Tamaoka, N
PMID: 21559711
Journal: Br J Cancer. 1994 Aug;70(2):239-43.
Title: Reversion of multidrug resistance in the P-glycoprotein-positive human pancreatic cell line (EPP85-181RDB) by introduction of a hammerhead ribozyme.
Author: Holm, P S|Scanlon, K J|Dietel, M
PMID: 7914421
Journal: Jpn J Cancer Res. 1996 Jun;87(6):641-9.
Title: Immunohistochemical localization of P-glycoprotein and expression of the multidrug resistance-1 gene in human pancreatic cancer: relevance to indicator of better prognosis.
Author: Suwa, H|Ohshio, G|Arao, S|Imamura, T|Yamaki, K|Manabe, T|Imamura, M|Hiai, H|Fukumoto, M
PMID: 8766529
Journal: Pancreas. 2000 Oct;21(3):240-7.
Title: Expression of the multidrug-resistance 1 (MDR1) gene and prognosis in human pancreatic cancer.
Author: Lu, Z|Kleeff, J|Shrikhande, S|Zimmermann, T|Korc, M|Friess, H|Buchler, M W
PMID: 11039467
Journal: J Surg Res. 2001 Aug;99(2):179-86.
Title: Mechanisms of taxotere-related drug resistance in pancreatic carcinoma.
Author: Liu, B|Staren, E D|Iwamura, T|Appert, H E|Howard, J M
PMID: 11469885
Journal: World J Gastroenterol. 2001 Dec;7(6):855-9.
Title: Taxotere resistance in SUIT Taxotere resistance in pancreatic carcinoma cell line SUIT 2 and its sublines.
Author: Liu, B|Staren, E|Iwamura, T|Appert, H|Howard, J
PMID: 11854916
Journal: FEBS Lett. 2003 Jun 19;545(2-3):144-50.
Title: Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi).
Author: Nieth, Christiane|Priebsch, Axel|Stege, Alexandra|Lage, Hermann
PMID: 12804765
Journal: Hepatobiliary Pancreat Dis Int. 2004 May;3(2):307-10.
Title: Detection of multidrug resistant gene 1 in pancreatic cancer.
Author: Zhao, Yu-Pei|Zhang, Li-Yang|Liao, Quan|Guo, Jun-Chao|Chen, Ge|Li, Jia-Yi
PMID: 15138133
Journal: Int J Cancer. 2005 Jun 20;115(3):359-67.
Title: Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma.
Author: Konig, Jorg|Hartel, Mark|Nies, Anne T|Martignoni, Marc E|Guo, Junchao|Buchler, Markus W|Friess, Helmut|Keppler, Dietrich
PMID: 15688370
Journal: Pathol Oncol Res. 2005;11(3):164-9.
Title: P-glycoprotein expression is induced in human pancreatic cancer xenografts during treatment with a cell cycle regulator, mimosine.
Author: Zalatnai, Attila
PMID: 16195770
Journal: J Gastroenterol Hepatol. 2007 Sep;22(9):1469-73. Epub 2007 Jul 20.
Title: Antineoplastic activity of 2-methoxyestradiol in human pancreatic and gastric cancer cells with different multidrug-resistant phenotypes.
Author: Schumacher, Guido|Hoffmann, Janine|Cramer, Thorsten|Spinelli, Antonino|Jacob, Dietmar|Bahra, Marcus|Pratschke, Johann|Pfitzmann, Robert|Schmidt, Sven|Lage, Hermann
PMID: 17645459
Journal: Anticancer Res. 2007 Jul-Aug;27(4B):2115-20.
Title: MDR1/P-glycoprotein and MRP-1 drug efflux pumps in pancreatic carcinoma.
Author: O'Driscoll, L|Walsh, N|Larkin, A|Ballot, J|Ooi, W S|Gullo, G|O'Connor, R|Clynes, M|Crown, J|Kennedy, S
PMID: 17695494
Journal: Zhonghua Wai Ke Za Zhi. 2007 Nov 1;45(21):1488-90.
Title: [Significance and reversal of MDR1/P-gp in pancreatic cancer chemotherapy].
Author: Guo, Jun-chao|Zhao, Yu-pei|Liao, Quan|Zhu, Yu
PMID: 18275717
Journal: World J Gastroenterol. 2008 Feb 14;14(6):925-30.
Title: Persistence of side population cells with high drug efflux capacity in pancreatic cancer.
Author: Zhou, Jing|Wang, Chun-You|Liu, Tao|Wu, Bin|Zhou, Feng|Xiong, Jiong-Xin|Wu, He-Shui|Tao, Jing|Zhao, Gang|Yang, Ming|Gou, Shan-Miao
PMID: 18240351
Journal: J Surg Res. 2008 Mar;145(1):111-23. Epub 2007 Aug 22.
Title: Effects of the proteasome inhibitor bortezomib on gene expression profiles of pancreatic cancer cells.
Author: Tang, Zhi-Yu|Wu, Yu-Lian|Gao, Shun-Liang|Shen, Hong-Wei
PMID: 17714734
Journal: Pancreatology. 2009;9(1-2):136-44.
Title: ATP-binding cassette C transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells.
Author: Hagmann, Wolfgang|Jesnowski, Ralf|Faissner, Ralf|Guo, Changqing|Lohr, J Matthias
PMID: 19077464
Journal: Pharmacogenomics J. 2009 Apr;9(2):90-102.
Title: Identification of genes that confer tumor cell resistance to the aurora B kinase inhibitor, AZD1152.
Author: Guo, J|Anderson, M G|Tapang, P|Palma, J P|Rodriguez, L E|Niquette, A|Li, J|Bouska, J J|Wang, G|Semizarov, D|Albert, D H|Donawho, C K|Glaser, K B|Shah, O J
PMID: 19188929
Journal: Int J Cancer. 2009 Nov 15;125(10):2323-31.
Title: CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells.
Author: Hong, Sung Pil|Wen, Jing|Bang, Seungmin|Park, Seungwoo|Song, Si Young
PMID: 19598259
Journal: Mol Cancer Ther. 2009 Nov;8(11):3098-107.
Title: Positive selection of gene-modified cells increases the efficacy of pancreatic cancer suicide gene therapy.
Author: Martinez-Quintanilla, Jordi|Cascallo, Manel|Gros, Alena|Fillat, Cristina|Alemany, Ramon
PMID: 19887556
Journal: Cancer Chemother Pharmacol. 2010 Oct;66(5):973-80.
Title: The maximum tolerated dose and biologic effects of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) in combination with irinotecan for patients with refractory solid tumors.
Author: Choi, Brian S|Alberti, Dona B|Schelman, William R|Kolesar, Jill M|Thomas, James P|Marnocha, Rebecca|Eickhoff, Jens C|Ivy, S Percy|Wilding, George|Holen, Kyle D
PMID: 20127092
Journal: Molecules. 2010 Feb 9;15(2):857-70.
Title: Quercetin as a potential modulator of P-glycoprotein expression and function in cells of human pancreatic carcinoma line resistant to daunorubicin.
Author: Borska, Sylwia|Sopel, Miroslaw|Chmielewska, Magdalena|Zabel, Maciej|Dziegiel, Piotr
PMID: 20335952
Journal: Zhonghua Wai Ke Za Zhi. 2010 Jul 1;48(13):999-1003.
Title: [Establish a gemcitabine-resistant pancreatic cancer cell line SW1990/GZ and research the relationship between SW1990/GZ and pancreatic cancer stem cell].
Author: An, Yong|Yao, Jie|Wei, Ji-Shu|Lu, Zi-Peng|Cai, Hui-Hua|Dai, Cun-Cai|Qian, Zhu-Yin|Xu, Ze-Kuan|Miao, Yi
PMID: 21054984
Journal: Cancer. 2011 Feb 15;117(4):744-51.
Title: Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.
Author: Tanaka, Motofumi|Okazaki, Taro|Suzuki, Hideo|Abbruzzese, James L|Li, Donghui
PMID: 20922799
Journal: Drug Metab Dispos. 2011 May;39(5):729-35.
Title: Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics.
Author: Poller, Birk|Iusuf, Dilek|Sparidans, Rolf W|Wagenaar, Els|Beijnen, Jos H|Schinkel, Alfred H
PMID: 21282407
Journal: PLoS One. 2011 Jan 31;6(1):e16530.
Title: Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition.
Author: Shankar, Sharmila|Nall, Dara|Tang, Su-Ni|Meeker, Daniel|Passarini, Jenna|Sharma, Jay|Srivastava, Rakesh K
PMID: 21304978
Journal: Mol Cancer Ther. 2011 Jul;10(7):1252-63.
Title: Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo.
Author: Yamazaki, Ryuta|Nishiyama, Yukiko|Furuta, Tomio|Hatano, Hiroshi|Igarashi, Yoshiaki|Asakawa, Naoyuki|Kodaira, Hiroshi|Takahashi, Hiroyuki|Aiyama, Ritsuo|Matsuzaki, Takeshi|Yagi, Nao|Sugimoto, Yoshikazu
PMID: 21566063
Journal: Hepatogastroenterology. 2012 Jan-Feb;59(113):272-5.
Title: Single nucleotide polymorphism of multidrug-resistance 1 and anti- multidrug-resistance 1 single chain antibody treatment for the pancreatic cancer cell line.
Author: Kasuya, Kazuhiko|Tsuchida, Akihiko|Suzuki, Minako|Nagakawa, Yuichi|Tanaka, Hiroaki|Ota, Hiroshi|Itoi, Takao|Aoki, Tatsuya
PMID: 21940367
Journal: BMC Mol Biol. 2012 Jul 30;13:25.
Title: Dual regulation of P-glycoprotein expression by trichostatin A in cancer cell lines.
Author: Balaguer, Trinidad Mata|Gomez-Martinez, Angeles|Garcia-Morales, Pilar|Lacueva, Javier|Calpena, Rafael|Reverte, Lourdes Rocamora|Riquelme, Natividad Lopez|Martinez-Lacaci, Isabel|Ferragut, Jose A|Saceda, Miguel
PMID: 22846052
Journal: Oncol Rep. 2012 May;27(5):1567-72.
Title: Inhibitory effects of epigallocatechin-3-gallate on cell proliferation and the expression of HIF-1alpha and P-gp in the human pancreatic carcinoma cell line PANC-1.
Author: Zhu, Zhenni|Wang, Yu|Liu, Zhiqing|Wang, Fan|Zhao, Qiu
PMID: 22367292
Journal: Oncol Rep. 2012 Jan;27(1):265-9.
Title: Expression and promoter methylation analysis of ATP-binding cassette genes in pancreatic cancer.
Author: Chen, Minyong|Xue, Xiaofeng|Wang, Feitong|An, Yong|Tang, Dong|Xu, Yue|Wang, Hui|Yuan, Zhongxu|Gao, Wentao|Wei, Jishu|Zhang, Jingjing|Miao, Yi
PMID: 21956451
Journal: Hepatogastroenterology. 2012 Jul-Aug;59(117):1609-13.
Title: Prediction of a side effect and efficacy of adjuvant chemotherapy with gemcitabine for post operative patient of pancreatic cancer by a genetic polymorphism analysis.
Author: Kasuya, Kazuhiko|Tsuchida, Akihiko|Nagakawa, Yuichi|Suzuki, Yoshiaki|Suzuki, Minako|Aoki, Tatsuya|Abe, Yuta|Shimazu, Motohide|Itoi, Takao|Sofuni, Atsushi
PMID: 22155850
Journal: Acta Histochem. 2013 May;115(4):349-56.
Title: CD133(+)/CD44(+)/Oct4(+)/Nestin(+) stem-like cells isolated from Panc-1 cell line may contribute to multi-resistance and metastasis of pancreatic cancer.
Author: Wang, Dongqing|Zhu, Haitao|Zhu, Ying|Liu, Yanfang|Shen, Huiling|Yin, Ruigen|Zhang, Zhijian|Su, Zhaoliang
PMID: 23036582
Journal: Mol Cancer Ther. 2013 Jan;12(1):58-68.
Title: Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer.
Author: Song, Bing|Liu, X Shawn|Rice, Steven J|Kuang, Shihuan|Elzey, Bennett D|Konieczny, Stephen F|Ratliff, Timothy L|Hazbun, Tony|Chiorean, Elena G|Liu, Xiaoqi
PMID: 23188630
Journal: Apoptosis. 2013 Jul;18(7):861-9.
Title: CacyBP/SIP enhances multidrug resistance of pancreatic cancer cells by regulation of P-gp and Bcl-2.
Author: Chen, Xiong|Zheng, Peichan|Xue, Zengfu|Li, Jie|Wang, Wenwu|Chen, Xi|Xie, Fangwei|Yu, Zongyang|Ouyang, Xuenong
PMID: 23463283
Journal: Anticancer Drugs. 2013 Jul;24(6):566-76.
Title: Induction of pancreatic cancer cell apoptosis, invasion, migration, and enhancement of chemotherapy sensitivity of gemcitabine, 5-FU, and oxaliplatin by hnRNP A2/B1 siRNA.
Author: Gu, Wen-Jun|Liu, Hai-Lin
PMID: 23525071
Journal: Oncogenesis. 2013 Jun 17;2:e51.
Title: MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes.
Author: Nath, S|Daneshvar, K|Roy, L D|Grover, P|Kidiyoor, A|Mosley, L|Sahraei, M|Mukherjee, P
PMID: 23774063
Journal: PLoS One. 2013 Sep 17;8(9):e73968.
Title: Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes.
Author: Van den Broeck, Anke|Vankelecom, Hugo|Van Delm, Wouter|Gremeaux, Lies|Wouters, Jasper|Allemeersch, Joke|Govaere, Olivier|Roskams, Tania|Topal, Baki
PMID: 24069258
Journal: Nucl Med Commun. 2014 Oct;35(10):1067-70.
Title: Interrogation of multidrug resistance (MDR1) P-glycoprotein (ABCB1) expression in human pancreatic carcinoma cells: correlation of 99mTc-Sestamibi uptake with western blot analysis.
Author: Harpstrite, Scott E|Gu, Hannah|Natarajan, Radhika|Sharma, Vijay
PMID: 25036383
Journal: Hepatogastroenterology. 2014 Nov-Dec;61(136):2395-401.
Title: Effects of hypoxia-inducible factor-1alpha silencing on drug resistance of human pancreatic cancer cell line Patu8988/5-Fu.
Author: Yang, Shi-Yong|Song, Bi-qing|Dai, Shu-Long|Yang, Kun-Xing|Jin-Zhou|Shi, Kai-Wang
PMID: 25699390
Journal: Oncol Rep. 2014 Nov;32(5):2015-22.
Title: Reversion of trichostatin A resistance via inhibition of the Wnt signaling pathway in human pancreatic cancer cells.
Author: Wang, Benquan|Zou, Qian|Sun, Meng|Chen, Jingfeng|Wang, Tianyang|Bai, Yongheng|Chen, Zongjing|Chen, Bicheng|Zhou, Mengtao
PMID: 25224651
Journal: Gastroenterol Res Pract. 2014;2014:414931.
Title: ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?
Author: Pang, Li|Word, Beverly|Xu, Joshua|Wang, Honggang|Hammons, George|Huang, Shiew-Mei|Lyn-Cook, Beverly
PMID: 24883056
Journal: Molecules. 2014 Apr 30;19(5):5611-23.
Title: miRNAs for the detection of multidrug resistance: overview and perspectives.
Author: Gisel, Andreas|Valvano, Mirna|El Idrissi, Imane Ghafir|Nardulli, Patrizia|Azzariti, Amalia|Carrieri, Antonio|Contino, Marialessandra|Colabufo, Nicola Antonio
PMID: 24786846
Journal: Clin Lymphoma Myeloma Leuk. 2014 Jun;14(3):215-22.
Title: Cyclin D1 amplification in multiple myeloma is associated with multidrug resistance expression.
Author: Sewify, Eman M|Afifi, Ola A|Mosad, Eman|Zaki, Amen H|El Gammal, Sahar A
PMID: 24468132
Journal: Int J Cancer. 2014 Jun 1;134(11):2656-62.
Title: Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer.
Author: Melson, Joshua|Li, Yan|Cassinotti, Elisa|Melnikov, Anatoliy|Boni, Luigi|Ai, Junmei|Greenspan, Michael|Mobarhan, Sohrab|Levenson, Victor|Deng, Youping
PMID: 24288256
Journal: Exp Mol Pathol. 2015 Feb;98(1):41-6.
Title: Pancreatic cancer cells express CD44 variant 9 and multidrug resistance protein 1 during mitosis.
Author: Kiuchi, Shizuka|Ikeshita, Shunji|Miyatake, Yukiko|Kasahara, Masanori
PMID: 25481101
Journal: PLoS One. 2015 Dec 28;10(12):e0144969.
Title: TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo.
Author: Cao, Jia|Yang, Jiachun|Ramachandran, Vijaya|Arumugam, Thiruvengadam|Deng, Defeng|Li, Zhaoshen|Xu, Leiming|Logsdon, Craig D
PMID: 26709920
Journal: Tumour Biol. 2016 Jun;37(6):7555-64.
Title: Silencing pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer cells to gemcitabine.
Author: Gao, Chong-Chong|Xu, Xiao-Lan|Li, Fei|Gong, Ben-Gang|Liu, Shuang|Cui, Ye-Qing|Sun, Hai-Chen|Xu, Ping-Yong|Zheng, Ya-Min|Jiang, Hua
PMID: 26684804
Journal: Oncotarget. 2016 Mar 15;7(11):12623-32.
Title: Expression of the bitter receptor T2R38 in pancreatic cancer: localization in lipid droplets and activation by a bacteria-derived quorum-sensing molecule.
Author: Gaida, Matthias M|Mayer, Christine|Dapunt, Ulrike|Stegmaier, Sabine|Schirmacher, Peter|Wabnitz, Guido H|Hansch, G Maria
PMID: 26862855
Journal: EJNMMI Res. 2016 Apr;6(Suppl 1):32.
Title: 32nd International Austrian Winter Symposium : Zell am See, the Netherlands. 20-23 January 2016.
Author: Langsteger, W|Rezaee, A|Loidl, W|Geinitz, H S|Fitz, F|Steinmair, M|Broinger, G|Pallwien-Prettner, L|Beheshti, M|Imamovic, L|Beheshti, M|Rendl, G|Hackl, D|Tsybrovsky, O|Steinmair, M|Emmanuel, K|Moinfar, F|Pirich, C|Langsteger, W|Bytyqi, A|Karanikas, G|Maye
PMID: 27090254
Journal: Oncotarget. 2017 Jan 31;8(5):7740-7752.
Title: Leptin-Notch signaling axis is involved in pancreatic cancer progression.
Author: Harbuzariu, Adriana|Rampoldi, Antonio|Daley-Brown, Danielle S|Candelaria, Pierre|Harmon, Tia L|Lipsey, Crystal C|Beech, Derrick J|Quarshie, Alexander|Ilies, Gabriela Oprea|Gonzalez-Perez, Ruben R
PMID: 27999190
Journal: Oncotarget. 2017 Feb 28;8(9):14620-14635.
Title: Genomic characteristics of pancreatic squamous cell carcinoma, an investigation by using high throughput sequencing after in-solution hybrid capture.
Author: Xu, Meng-Dan|Liu, Shu-Ling|Feng, Yi-Zhong|Liu, Qiang|Shen, Meng|Zhi, Qiaoming|Liu, Zeyi|Gu, Dong-Mei|Yu, Jie|Shou, Liu-Mei|Gong, Fei-Ran|Zhu, Qi|Duan, Weiming|Chen, Kai|Zhang, Junning|Wu, Meng-Yao|Tao, Min|Li, Wei
PMID: 28099906
Journal: Int J Cancer. 2017 Nov 15;141(10):2131-2142.
Title: GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts.
Author: Bernier, Michel|Catazaro, Jonathan|Singh, Nagendra S|Wnorowski, Artur|Boguszewska-Czubara, Anna|Jozwiak, Krzysztof|Powers, Robert|Wainer, Irving W
PMID: 28741686
Journal: Biochem Biophys Res Commun. 2018 Apr 30;499(1):37-43.
Title: Detection and proteomic characterization of extracellular vesicles in human pancreatic juice.
Author: Osteikoetxea, Xabier|Benke, Marton|Rodriguez, Marta|Paloczi, Krisztina|Sodar, Barbara W|Szvicsek, Zsuzsanna|Szabo-Taylor, Katalin|Vukman, Krisztina V|Kittel, Agnes|Wiener, Zoltan|Vekey, Karoly|Harsanyi, Laszlo|Szucs, Akos|Turiak, Lilla|Buzas, Edit I
PMID: 29550476