Primary Site >> Colorectal Cancer
Gene >> ZNRF3
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Ref: Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. PMID: 22895187 |
Ref: Oncogenic Wnt/beta-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research. PMID: 23155044 |
Ref: RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancer. PMID: 24476626 Ref: The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength. PMID: 24532711 |
Ref: RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. PMID: 27661107 Ref: Association between prognostic survival of human colorectal carcinoma and ZNRF3 expression. PMID: 27822070 |
Ref: RSPO2 suppresses colorectal cancer metastasis by counteracting the Wnt5a/Fzd7-driven noncanonical Wnt pathway. PMID: 28600110 Ref: Molecular genetics and targeted therapy of WNT-related human diseases (Review). PMID: 28731148 |
Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 |