Primary Site >> Pancreatic Cancer

Gene >> ZG16B

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Ref: Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel up-regulated secretory protein in pancreatic ductal adenocarcinoma.
PMID: 19302292
 Ref: PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression.
PMID: 19784070
 Ref: Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of beta-catenin, leading to a rapid proliferation of pancreatic cells.
PMID: 21196815
Ref: An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells.
PMID: 21963224
 Ref: SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of beta-catenin.
PMID: 22640743
 Ref: Pancreatic adenocarcinoma upregulated factor, a novel endothelial activator, promotes angiogenesis and vascular permeability.
PMID: 22907431
 Ref: Pancreatic adenocarcinoma upregulated factor (PAUF) confers resistance to pancreatic cancer cells against oncolytic parvovirus H-1 infection through IFNA receptor-mediated signaling.
PMID: 25727013
Ref: Pancreatic adenocarcinoma upregulated factor serves as adjuvant by activating dendritic cells through stimulation of TLR4.
PMID: 26336989
 Ref: Silencing pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer cells to gemcitabine.
PMID: 26684804
Ref: Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer.
PMID: 27322081
 Ref: Pancreatic adenocarcinoma up-regulated factor has oncogenic functions in oral squamous cell carcinoma.
PMID: 27706833
Ref: DCPP1 is the mouse ortholog of human PAUF that possesses functional analogy in pancreatic cancer.
PMID: 28988106
Ref: Suppression of pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer to gemcitabine and 5FU, and inhibits the formation of pancreatic cancer stem like cells.
PMID: 29100320
 Ref: Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer.
PMID: 30111860