Primary Site >> Biliary tract Cancer
Gene >> YAP1
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Ref: Deregulation of Hippo kinase signalling in human hepatic malignancies. PMID: 22098159 |
Ref: The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease. PMID: 24746211 Ref: Activation of beta-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice. PMID: 24837480 Ref: Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation. PMID: 24892809 Ref: Yes-associated protein 1 (YAP1) promotes human gallbladder tumor growth via activation of the AXL/MAPK pathway. PMID: 25218593 |
Ref: YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors. PMID: 26173433 |
Ref: Dysregulated YAP1/TAZ and TGF-beta signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. PMID: 26699479 Ref: Clinicopathological and prognostic significance of Yes-associated protein expression in hepatocellular carcinoma and hepatic cholangiocarcinoma. PMID: 27465555 |
Ref: Altered Expression of Hippo Signaling Pathway Molecules in Intrahepatic Cholangiocarcinoma. PMID: 28448997 Ref: The correlation between poor prognosis and increased yes-associated protein 1 expression in keratin 19 expressing hepatocellular carcinomas and cholangiocarcinomas. PMID: 28645247 Ref: Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice. PMID: 28733220 Ref: Molecular alterations of the NF2 gene in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. PMID: 29130106 |
Ref: Hippo Cascade Controls Lineage Commitment of Liver Tumors in Mice and Humans. PMID: 29378174 Ref: Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice. PMID: 29545603 |