Primary Site >> Colorectal Cancer
Gene >> XAF1
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Ref: Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. PMID: 14583479 |
Ref: Low expression of XIAP-associated factor 1 in human colorectal cancers. PMID: 15667552 Ref: [Frequent epigenetic inactivation of XAF1 by promotor hypermethylation in human colon cancers]. PMID: 15843754 |
Ref: All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer. PMID: 16530516 Ref: Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. PMID: 17087954 |
Ref: Potent antitumor efficacy of XAF1 delivered by conditionally replicative adenovirus vector via caspase-independent apoptosis. PMID: 17008933 Ref: Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15. PMID: 17195906 Ref: XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer. PMID: 17385215 Ref: Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses. PMID: 17570219 Ref: [Expression of HSF1 and XAF1 in gastro-intestinal cancer]. PMID: 17884799 |
Ref: Regulation of XAF1 expression in human colon cancer cell by interferon beta: activation by the transcription regulator STAT1. PMID: 18035482 Ref: Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in colon cancer cells. PMID: 18362468 Ref: [Expression of heat-shock transcription factor 1 and X-linked inhibitor of apoptosis protein-associated factor-1 in gastrointestinal cancer]. PMID: 18546582 |
Ref: Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression. PMID: 20082449 |
Ref: The effect of combining interferon-alpha and gefitinib in human colon cancer cell lines. PMID: 21942111 |
Ref: XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification. PMID: 21678496 |
Ref: Combination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells. PMID: 24874286 Ref: X-linked inhibitor of apoptosis-associated factor l (XAFl) enhances the sensitivity of colorectal cancer cells to cisplatin. PMID: 25367849 |
Ref: Identification of XAF1-MT2A mutual antagonism as a molecular switch in cell-fate decisions under stressful conditions. PMID: 28507149 Ref: Ampelopsin-induced reactive oxygen species enhance the apoptosis of colon cancer cells by activating endoplasmic reticulum stress-mediated AMPK/MAPK/XAF1 signaling. PMID: 29250183 |
Ref: Sensitization of colorectal cancer cells to irinotecan by the Survivin inhibitor LLP3 depends on XAF1 proficiency in the context of mutated p53. PMID: 29947891 Ref: Replica to the Opinion Letter regarding the article "Sensitization of colorectal cancer cells to irinotecan by the Survivin inhibitor LLP3 depends on XAF1 proficiency in the context of mutated p53" (Arch Toxicol https://doi.org/10.1007/s00204-018-240-x). PMID: 30120489 |